Evolution, Autism and Social Change
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How Morphological Development Can Guide Evolution Sam Kriegman1,*, Nick Cheney1, and Josh Bongard1
How morphological development can guide evolution Sam Kriegman1,*, Nick Cheney1, and Josh Bongard1 1University of Vermont, Department of Computer Science, Burlington, VT, USA *[email protected] ABSTRACT Organisms result from adaptive processes interacting across different time scales. One such interaction is that between development and evolution. Models have shown that development sweeps over several traits in a single agent, sometimes exposing promising static traits. Subsequent evolution can then canalize these rare traits. Thus, development can, under the right conditions, increase evolvability. Here, we report on a previously unknown phenomenon when embodied agents are allowed to develop and evolve: Evolution discovers body plans robust to control changes, these body plans become genetically assimilated, yet controllers for these agents are not assimilated. This allows evolution to continue climbing fitness gradients by tinkering with the developmental programs for controllers within these permissive body plans. This exposes a previously unknown detail about the Baldwin effect: instead of all useful traits becoming genetically assimilated, only traits that render the agent robust to changes in other traits become assimilated. We refer to this as differential canalization. This finding also has implications for the evolutionary design of artificial and embodied agents such as robots: robots robust to internal changes in their controllers may also be robust to external changes in their environment, such as transferal from simulation to reality or deployment in novel environments. Introduction The shape of life changes on many different time scales. From generation to generation, populations gradually increase in complexity and relative competency. At the individual level, organisms grow from a single-celled egg and exhibit extreme postnatal change as they interact with the outside world during their lifetimes. -
Transformations of Lamarckism Vienna Series in Theoretical Biology Gerd B
Transformations of Lamarckism Vienna Series in Theoretical Biology Gerd B. M ü ller, G ü nter P. Wagner, and Werner Callebaut, editors The Evolution of Cognition , edited by Cecilia Heyes and Ludwig Huber, 2000 Origination of Organismal Form: Beyond the Gene in Development and Evolutionary Biology , edited by Gerd B. M ü ller and Stuart A. Newman, 2003 Environment, Development, and Evolution: Toward a Synthesis , edited by Brian K. Hall, Roy D. Pearson, and Gerd B. M ü ller, 2004 Evolution of Communication Systems: A Comparative Approach , edited by D. Kimbrough Oller and Ulrike Griebel, 2004 Modularity: Understanding the Development and Evolution of Natural Complex Systems , edited by Werner Callebaut and Diego Rasskin-Gutman, 2005 Compositional Evolution: The Impact of Sex, Symbiosis, and Modularity on the Gradualist Framework of Evolution , by Richard A. Watson, 2006 Biological Emergences: Evolution by Natural Experiment , by Robert G. B. Reid, 2007 Modeling Biology: Structure, Behaviors, Evolution , edited by Manfred D. Laubichler and Gerd B. M ü ller, 2007 Evolution of Communicative Flexibility: Complexity, Creativity, and Adaptability in Human and Animal Communication , edited by Kimbrough D. Oller and Ulrike Griebel, 2008 Functions in Biological and Artifi cial Worlds: Comparative Philosophical Perspectives , edited by Ulrich Krohs and Peter Kroes, 2009 Cognitive Biology: Evolutionary and Developmental Perspectives on Mind, Brain, and Behavior , edited by Luca Tommasi, Mary A. Peterson, and Lynn Nadel, 2009 Innovation in Cultural Systems: Contributions from Evolutionary Anthropology , edited by Michael J. O ’ Brien and Stephen J. Shennan, 2010 The Major Transitions in Evolution Revisited , edited by Brett Calcott and Kim Sterelny, 2011 Transformations of Lamarckism: From Subtle Fluids to Molecular Biology , edited by Snait B. -
Study of Natural Longlife Juvenility and Tissue Regeneration in Caudate Amphibians and Potential Application of Resulting Data in Biomedicine
Journal of Developmental Biology Review Study of Natural Longlife Juvenility and Tissue Regeneration in Caudate Amphibians and Potential Application of Resulting Data in Biomedicine Eleonora N. Grigoryan Kol’tsov Institute of Developmental Biology, Russian Academy of Sciences, 119334 Moscow, Russia; [email protected]; Tel.: +7-(499)-1350052 Abstract: The review considers the molecular, cellular, organismal, and ontogenetic properties of Urodela that exhibit the highest regenerative abilities among tetrapods. The genome specifics and the expression of genes associated with cell plasticity are analyzed. The simplification of tissue structure is shown using the examples of the sensory retina and brain in mature Urodela. Cells of these and some other tissues are ready to initiate proliferation and manifest the plasticity of their phenotype as well as the correct integration into the pre-existing or de novo forming tissue structure. Without excluding other factors that determine regeneration, the pedomorphosis and juvenile properties, identified on different levels of Urodele amphibians, are assumed to be the main explanation for their high regenerative abilities. These properties, being fundamental for tissue regeneration, have been lost by amniotes. Experiments aimed at mammalian cell rejuvenation currently use various approaches. They include, in particular, methods that use secretomes from regenerating tissues of caudate amphibians and fish for inducing regenerative responses of cells. Such an approach, along with those developed on the basis of knowledge about the molecular and genetic nature and age dependence of regeneration, may become one more step in the development of regenerative medicine Citation: Grigoryan, E.N. Study of Keywords: salamanders; juvenile state; tissue regeneration; extracts; microvesicles; cell rejuvenation Natural Longlife Juvenility and Tissue Regeneration in Caudate Amphibians and Potential Application of Resulting Data in 1. -
Eugenics, Biopolitics, and the Challenge of the Techno-Human Condition
Nathan VAN CAMP Redesigning Life The emerging development of genetic enhancement technologies has recently become the focus of a public and philosophical debate between proponents and opponents of a liberal eugenics – that is, the use of Eugenics, Biopolitics, and the Challenge these technologies without any overall direction or governmental control. Inspired by Foucault’s, Agamben’s of the Techno-Human Condition and Esposito’s writings about biopower and biopolitics, Life Redesigning the author sees both positions as equally problematic, as both presuppose the existence of a stable, autonomous subject capable of making decisions concerning the future of human nature, while in the age of genetic technology the nature of this subjectivity shall be less an origin than an effect of such decisions. Bringing together a biopolitical critique of the way this controversial issue has been dealt with in liberal moral and political philosophy with a philosophical analysis of the nature of and the relation between life, politics, and technology, the author sets out to outline the contours of a more responsible engagement with genetic technologies based on the idea that technology is an intrinsic condition of humanity. Nathan VAN CAMP Nathan VAN Philosophy Philosophy Nathan Van Camp is postdoctoral researcher at the University of Antwerp, Belgium. He focuses on continental philosophy, political theory, biopolitics, and critical theory. & Politics ISBN 978-2-87574-281-0 Philosophie & Politique 27 www.peterlang.com P.I.E. Peter Lang Nathan VAN CAMP Redesigning Life The emerging development of genetic enhancement technologies has recently become the focus of a public and philosophical debate between proponents and opponents of a liberal eugenics – that is, the use of Eugenics, Biopolitics, and the Challenge these technologies without any overall direction or governmental control. -
Evolution, Politics and Law
Valparaiso University Law Review Volume 38 Number 4 Summer 2004 pp.1129-1248 Summer 2004 Evolution, Politics and Law Bailey Kuklin Follow this and additional works at: https://scholar.valpo.edu/vulr Part of the Law Commons Recommended Citation Bailey Kuklin, Evolution, Politics and Law, 38 Val. U. L. Rev. 1129 (2004). Available at: https://scholar.valpo.edu/vulr/vol38/iss4/1 This Article is brought to you for free and open access by the Valparaiso University Law School at ValpoScholar. It has been accepted for inclusion in Valparaiso University Law Review by an authorized administrator of ValpoScholar. For more information, please contact a ValpoScholar staff member at [email protected]. Kuklin: Evolution, Politics and Law VALPARAISO UNIVERSITY LAW REVIEW VOLUME 38 SUMMER 2004 NUMBER 4 Article EVOLUTION, POLITICS AND LAW Bailey Kuklin* I. Introduction ............................................... 1129 II. Evolutionary Theory ................................. 1134 III. The Normative Implications of Biological Dispositions ......................... 1140 A . Fact and Value .................................... 1141 B. Biological Determinism ..................... 1163 C. Future Fitness ..................................... 1183 D. Cultural N orm s .................................. 1188 IV. The Politics of Sociobiology ..................... 1196 A. Political Orientations ......................... 1205 B. Political Tactics ................................... 1232 V . C onclusion ................................................. 1248 I. INTRODUCTION -
Life and Mind: from Autopoiesis to Neurophenomenology. a Tribute to Francisco Varela1
Phenomenology and the Cognitive Sciences 3: 381–398, 2004. C 2004 Kluwer Academic Publishers. Printed in the Netherlands. Life and mind: From autopoiesis to neurophenomenology. A tribute to Francisco Varela1 EVAN THOMPSON Canada Research Chair in Cognitive Science and the Embodied Mind, Department of Philosophy, York University (E-mail: [email protected]) Abstract. This talk, delivered at “De l’autopoi`eseal ` aneuroph´enom´enologie: un hommagea ` Francisco Varela;from autopoiesis to neurophenomenology: a tribute to Francisco Varela,” June 18–20, at the Sorbonne in Paris, explicates several links between Varela’sneurophenomenology and his biological concept of autopoiesis. Key words: autopoiesis, lived body, neurophenomenology, teleology, Varela Allow me to begin on a personal note. I first met Francisco Varela in the summer of 1977 at a conference called “Mind in Nature.” The conference wasorganized by my father, William Irwin Thompson, and Gregory Bateson. It took place in Southampton, New York, at the Lindisfarne Association, an institute founded by my father, and was chaired by Bateson, who was then serving as Lindisfarne’s Scholar-in-Residence.2 Iwas not quite 15-years old; Francisco was almost 32. At that time Francisco was known within the cir- cle of second-generation cybernetics and systems theory for his work with Maturana on autopoiesis and for his “calculus of self-reference” (Varela et al., 1974; Maturana and Varela, 1975; Varela 1975). But outside this circle he was known for an interview and a paper that had appeared about a year earlier in Coevolution Quarterly,awidely read intellectual journal of the American counterculture in the 1970s (Varela 1976a,b). -
A Metaphysical Approach to Environmental Sustainability- Alfred
A METAPHYSICAL APPROACH TO ENVIRONMENTAL SUSTAINABILITY: ALFRED NORTH WHITEHEAD’S PROCESS PHILOSOPHY By DYNESIUS NYANGAU C50/79646/2015 A Research Project Submitted in Partial Fulfillment of the Requirements for the Award of the Degree of Master of Arts in Philosophy, University of Nairobi 2016 DECLARATION I declare that this research project is my original work and has not been presented for examination in any other university. __________________________ _______________________________ Sign Date Dynesius Nyangau C50/79646/2015 This research project has been submitted for examination with my approval as the university supervisor. ____________________________ _______________________________ Sign Date Dr. Patrick O. Nyabul Department of Philosophy and Religious Studies University of Nairobi ii DEDICATION To the late Professor Joseph Nyasani, in whose sense of duty I will ever remain, for his acerbic academic discernment, resolute inspiration and unflagging demonstration of the most philosophical audacity, charity and bounteousness in the face of great hardship. iii ACKNOWLEDGEMENT I hold with esteem the input of Prof. Stephen Ifedha Akaranga, the Head of Department of Philosophy and Religious Studies for his specific contribution on methodology while working on this document. I remain indebted to my supervisor Dr. Patrick O. Nyabul for his dedication, continuous review and guidance throughout the study. I acknowledge with gratitude the input of Prof. Karori Mbugua and Prof. Solomon Monyenye who listened, critiqued, and helped me organize my thoughts before beginning to put down the proposal for this project. I thank my educators Dr. Francis Owakah and Dr. Oriare Nyarwath, whose constructive criticism and input helped shape up this work. I express gratitude to Dr. -
Personality Traits in Competition Dogs – a Quantitative Genetic Study on Competition Dogs
Faculty of Veterinary Medicine and Animal Science Personality traits in competition dogs – A quantitative genetic study on competition dogs Evelina Kess Master´s thesis • 30 credits Animal Science Uppsala 2019 Personality traits in competition dogs – A quantitative genetic study on competition dogs Personlighet hos tävlingshundar – En kvantitativ genetisk studie på tävlingshundar Evelina Kess Supervisor: Katja Nilsson, Swedish University of Agricultural Sciences, Department of Animal Breeding and Genetics Examiner: Erling Strandberg, Swedish University of Agricultural Sciences, Department of Animal Breeding and Genetics Credits: 30 credits Level: Second cycle, A2E Course title: Independent project in Animal Science Course code: EX0870 Programme/education: Animal Science Course coordinating department: Department of Animal Breeding and Genetics Place of publication: Uppsala Year of publication: 2019 Online publication: https://stud.epsilon.slu.se Cover photo: Carla Schmeyer Keywords: dog, personality, competition, heritability, dog mentality assessment, IPO, IGP, German shepherd, Belgian shepherd Malinois, Dutch Shepherd Swedish University of Agricultural Sciences Faculty of Veterinary Medicine and Animal Science Department of Animal Breeding and Genetics Abstract The purpose of this study was to investigate the relationship between per- formance and personality in three working dog breeds. The breeds that were chosen were the German Shepherd, the Belgian Shepherd Malinois and the Dutch Shepherd (Short haired). Pedigree data included pedigrees from 28536 dogs, out of those dogs 26 572 dogs also had personality test data and 1714 of those dogs had IPO results. The relationship between success in IPO and the five personality traits Playfulness, Curiosity/Fearlessness, Chase-prone- ness, Sociability and Aggressiveness was analysed using a linear model. Questionnaire data from a modified C-BARQ about everyday behaviour was also collected for analysis. -
Differences in Neural Stem Cell Identity and Differentiation Capacity Drive Divergent Regenerative Outcomes in Lizards and Salamanders
Differences in neural stem cell identity and differentiation capacity drive divergent regenerative outcomes in lizards and salamanders Aaron X. Suna,b,c, Ricardo Londonoa, Megan L. Hudnalla, Rocky S. Tuana,c, and Thomas P. Lozitoa,1 aCenter for Cellular and Molecular Engineering, Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219; bMedical Scientist Training Program, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213; and cDepartment of Bioengineering, University of Pittsburgh Swanson School of Engineering, Pittsburgh, PA 15213 Edited by Robb Krumlauf, Stowers Institute for Medical Research, Kansas City, MO, and approved July 24, 2018 (received for review March 2, 2018) While lizards and salamanders both exhibit the ability to re- lizard tail regenerate (20), and the key to understanding this generate amputated tails, the outcomes achieved by each are unique arrangement of tissues is in identifying the patterning markedly different. Salamanders, such as Ambystoma mexicanum, signals involved. regenerate nearly identical copies of original tails. Regenerated lizard Both lizards and salamanders follow similar mechanisms of tails, however, exhibit important morphological differences compared tail development during embryonic development. The embryonic with originals. Some of these differences concern dorsoventral pat- spinal cord and surrounding structures are formed and patterned terning of regenerated skeletal and spinal cord tissues; regenerated by the neural tube (21, 22). The neural tube exhibits distinct + salamander tail tissues exhibit dorsoventral patterning, while re- domains: roof plate (characterized by expression of Pax7 , BMP- + + + grown lizard tissues do not. Additionally, regenerated lizard tails lack 2 , and Sox10 among others), lateral domain (Pax6 ), and floor + + characteristically roof plate-associated structures, such as dorsal root plate (Shh , FoxA2 ). -
Of Syntheses and Surprises: Toward a Critical Integral Theory
Of Syntheses and Surprises: Toward a Critical Integral Theory Daniel Gustav Anderson Abstract: The central concern of this article is how the search for formal structures with universal values functions ideologically, addressing Zizek’s claim that East-West syntheses may represent the dominant ideology par excellance of global capitalism. To this end, the article offers a Foucaultian genealogy of Integral theory, tracing its origins to the cultural and subjective contingencies of the British Empire, primarily in the work of Integral theory’s foundational thinker, Aurobindo Ghose. The article poses a primary critique of synthesis and evolution as mythological keys to Ultimate Reality which suggests that Zizek’s critique may have some validity, and offers the potential for a “critical integral theory” as an alternative. Situated in Deleuze and Guattari’s concept of becoming, and represented in the ideas and practices of a constellation of thinkers inclusive of Gurdjieff, Benjamin, and Trungpa, the article’s view of integration supports radical democracy as presented in the writings of Laclau and Mouffe as a model outcome for social and personal transformational practices. Keywords: ideology, integral, critical, becoming-other, transformational practice, Aurobindo, Deleuze, Guattari, Ziporyn, Tarthang, Trungpa, Benjamin, Gurdjieff, Laclau, Mouffe, Zizek Introduction In On Belief, Slavoj Zizek (2001) argues that the onslaught of the New Age ‘Asiatic’ thought, which, in its different guises, from the ‘Western Buddhism’ (today’s counterpoint to Western Marxism, as opposed to the ‘Asiatic’ Marxism-Leninism) to different ‘Taos,’ is establishing itself as the hegemonic1 ideology of global capitalism (p. 12). 1 A detailed examination of hegemony as a critical concept is beyond the scope of this paper. -
Genetics of Canine Behavior
ACTA VET. BRNO 2007, 76: 431-444; doi:10.2754/avb200776030431 Review article Genetics of Canine Behavior K.A. HOUPT American College of Veterinary Behaviorists, Animal Behavior Clinic, Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA Received February 6, 2007 Accepted June 5, 2007 Abstract Houpt K.A.: Genetics of Canine Behavior. Acta Vet. Brno 2007, 76: 431-444. Canine behavioral genetics is a rapidly moving area of research. In this review, breed differences in behavior are emphasized. Dog professionals’ opinions of the various breeds on many behavior traits reveal factors such as reactivity, aggression, ease of training and immaturity. Heritability of various behaviors – hunting ability, playfulness, and aggression to people and other dogs – has been calculated. The neurotransmitters believed to be involved in aggression are discussed. The gene for aggression remains elusive, but identifi cation of single nucleotide polymorphisms associated with breed-specifi c behavior traits are leading us in the right direction. The unique syndrome of aggression found in English Springer Spaniels may be a model for detecting the gene involved. Dog aggression, heritability, temperament Behavior is a result of nature (genetics) and nurture (learning or experience). We shall review the history of canine behavioral genetics and explore the latest fi ndings. The publication of the canine genome allows us to make some inferences (Kirkness et al. 2003). Foxes One of the most thorough studies of canid behavioral genetics deals with foxes, not dogs. Selection for a tame and for an aggressive strain of silver foxes over 30 years by Dmitry Belyaev and Lyudmila Trut resulted in large differences in behavior and in morphology (Trut et al. -
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LivingLit 04 8/30/04 5:45 PM Page 158 158 The Cultural Phenomenology of Literature by William Irwin Thompson Introduction First of all, I would like to thank you for inviting me back to York for this conference, for this is a particularly appropriate time for me to return. If I were still on the faculty at York, this would be the year of my compul- sory retirement, so I look upon this as my Last Lecture or Swan Song. It is doubly appropriate for me to give this lecture here, for it was in this very room in 1971 when I was an Associate Professor of Humanities that I organized a conference entitled “Thinking on a Planetary Scale,” to which I invited the global theorist Bucky Fuller, the ecological archi- tect Paolo Soleri, and Richard Falk, Professor of International Law at the Woodrow Wilson School at Princeton. The conference was my eVort to express to my colleagues that business as usual was not enough and that we were living through a radical juncture in history in which a new planetary culture was emerging, a culture that was distinct from the internationalism that had characterized the world-system since the end of World War II.1 Wissenschaft und Wissenskunst Since B. W. Powe has asked us in this conference to think about the meaning of literacy in an electronic age, let me take a moment to address myself to this, the central question of our gathering. In my own writings of the time when I was here at York – in works such as At the Edge of History and Passages about Earth – I tried to use the structure of Romantic “Poems of Description and Meditation,” as the internal structure for non-fiction essays.2 In this work, I was also trying to respond to the challenge of Marshall McLuhan’s work.