Ralph Merkle
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The Effect of Birthday on the Fluctuation of Suicides in Hungary
REVIEW OF SOCIOLOGY 20(2): 96–105. The Effect of Birthday on the Fluctuation of Suicides STUDIES in Hungary (1970–2002) Tamás ZONDA – Károly BOZSONYI – Előd VERES – Zoltán KMEttY email: [email protected], [email protected], [email protected], [email protected] ABSTRACT: The authors have not found any studies that show an unambiguous and close relation between the date of suicide and the birthday of the victims. They made an analysis on the Hungarian suicides between 1970 and 2002 with a method known from the literature and also with a modern, more sophisticated one. It was found that Hungarian men show explicit sensitivity to their birthday’s date: significantly more men commit suicide on their birthday in all age groups than on any other day of the year. Among women, a relation of weak significance appeared only in the older age group. The authors suggest the special sensitivity of Hungarian men which they interpret in the framework of Gabennesch’s ”broken promise effect”, but they think it necessary to do further research on this theme in Hungary. Introduction Researches in the past decades have revealed several circumstances in the back- ground of a particular suicide that are generally typical and almost identical in every fatal action, but many circumstances and relationships that are inter- pretable or understandable with difficulty are discovered during the precise reconstruction of a tragic action. The decision of self-destruction is composed of a complicated mesh of numerous life events, injuries and constellations of personality development. It is known that certain biographical dates affect the personality to a greater or lesser extent. -
Diamondoid Mechanosynthesis Prepared for the International Technology Roadmap for Productive Nanosystems
IMM White Paper Scanning Probe Diamondoid Mechanosynthesis Prepared for the International Technology Roadmap for Productive Nanosystems 1 August 2007 D.R. Forrest, R. A. Freitas, N. Jacobstein One proposed pathway to atomically precise manufacturing is scanning probe diamondoid mechanosynthesis (DMS): employing scanning probe technology for positional control in combination with novel reactive tips to fabricate atomically-precise diamondoid components under positional control. This pathway has its roots in the 1986 book Engines of Creation, in which the manufacture of diamondoid parts was proposed as a long-term objective by Drexler [1], and in the 1989 demonstration by Donald Eigler at IBM that individual atoms could be manipulated by a scanning tunelling microscope [2]. The proposed DMS-based pathway would skip the intermediate enabling technologies proposed by Drexler [1a, 1b, 1c] (these begin with polymeric structures and solution-phase synthesis) and would instead move toward advanced DMS in a more direct way. Although DMS has not yet been realized experimentally, there is a strong base of experimental results and theory that indicate it can be achieved in the near term. • Scanning probe positional assembly with single atoms has been successfully demonstrated in by different research groups for Fe and CO on Ag, Si on Si, and H on Si and CNHCH3. • Theoretical treatments of tip reactions show that carbon dimers1 can be transferred to diamond surfaces with high fidelity. • A study on tip design showed that many variations on a design turn out to be suitable for accurate carbon dimer placement. Therefore, efforts can be focused on the variations of tooltips of many kinds that are easier to synthesize. -
Classification of Cell Death
Cell Death and Differentiation (2005) 12, 1463–1467 & 2005 Nature Publishing Group All rights reserved 1350-9047/05 $30.00 www.nature.com/cdd News and Commentary Classification of cell death: recommendations of the Nomenclature Committee on Cell Death G Kroemer*,1, WS El-Deiry2, P Golstein3, ME Peter4, D Vaux5, with or without, caspase activation and that ‘autophagic cell P Vandenabeele6, B Zhivotovsky7, MV Blagosklonny8, death’ represents a type of cell death with (but not necessarily W Malorni9, RA Knight10, M Piacentini11, S Nagata12 and through) autophagic vacuolization. This article details the G Melino10,13 2005 recommendations of NCCD. Over time, molecular definitions are expected to emerge for those forms of cell 1 CNRS-UMR8125, Institut Gustave Roussy, 39 rue Camille-Desmoulins, death that remain descriptive. F-94805 Villejuif, France 2 University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA Preface 3 Centre d’Immunologie INSERM/CNRS/Universite de la Mediterranee de Marseille-Luminy, Case 906, Avenue de Luminy, 13288 Marseille Cedex 9, It is obvious that clear definitions of objects that are only France shadows in Plato’s cage are difficult to be achieved. Cell death 4 The Ben May Institute for Cancer Research, University of Chicago, 924 E 57th and the different subroutines leading to cell death do not Street, Chicago, IL 60637, USA 5 escape this rule. Even worse, the notion of death is strongly Sir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, influenced by religious and cultural beliefs, which may UK 6 Molecular Signalling and Cell Death Unit, Department for Molecular Biomedical subliminally influence the scientific view of cell death. -
Medical-Legal Aspects of Cryonics: Prospects for Immortality Ethical - Legal and Social Challenges to a Brave New World Genetics - Ethics and the Law
Journal of Contemporary Health Law & Policy (1985-2015) Volume 2 Issue 1 Article 13 1986 Medical-Legal Aspects of Cryonics: Prospects for Immortality Ethical - Legal and Social Challenges to a Brave New World Genetics - Ethics and the Law Harold A. Buetow Follow this and additional works at: https://scholarship.law.edu/jchlp Recommended Citation Harold A. Buetow, Medical-Legal Aspects of Cryonics: Prospects for Immortality Ethical - Legal and Social Challenges to a Brave New World Genetics - Ethics and the Law, 2 J. Contemp. Health L. & Pol'y 173 (1986). Available at: https://scholarship.law.edu/jchlp/vol2/iss1/13 This Book Review is brought to you for free and open access by CUA Law Scholarship Repository. It has been accepted for inclusion in Journal of Contemporary Health Law & Policy (1985-2015) by an authorized editor of CUA Law Scholarship Repository. For more information, please contact [email protected]. BOOK REVIEWS MEDICAL-LEGAL ASPECTS OF CRYONICS: PROSPECTS FOR IMMORTALITY. New York City: Associated Faculty Press 1983. Pp. 81. $12.00. ETHICAL, LEGAL AND SOCIAL CHALLENGES TO A BRAVE NEW WORLD. New York City: Associated Faculty Press 2 Vols. 1982. 1 Vol. Pp. 286, $32.00. 2 Vol. Pp. 264, $28.50. GENETICS, ETHICS AND THE LAW. By George P. Smith, II. New York City: Associated Faculty Press, 1981. Pp. 241. $28.50, cloth; $18.50, paper. Reviewed by Harold A. Buetow, M.A., Ph.D., J.D. In 1968, the University of Michigan Law Review published an article enti- tled, "Through A Test Tube Darkly: Artificial Insemination and The Law."' Its author was George P. -
Looking Back Featured Stories from the Past
ISSN-1079-7832 A Publication of the Immortalist Society Longevity Through Technology Volume 49 - Number 01 Looking Back Featured stories from the past www.immortalistsociety.org www.cryonics.org www.americancryonics.org Who will be there for YOU? Don’t wait to make your plans. Your life may depend on it. Suspended Animation fields teams of specially trained cardio-thoracic surgeons, cardiac perfusionists and other medical professionals with state-of-the-art equipment to provide stabilization care for Cryonics Institute members in the continental U.S. Cryonics Institute members can contract with Suspended Animation for comprehensive standby, stabilization and transport services using life insurance or other payment options. Speak to a nurse today about how to sign up. Call 1-949-482-2150 or email [email protected] MKMCAD160206 216 605.83A SuspendAnim_Ad_1115.indd 1 11/12/15 4:42 PM Why should You join the Cryonics Institute? The Cryonics Institute is the world’s leading non-profit cryonics organization bringing state of the art cryonic suspensions to the public at the most affordable price. CI was founded by the “father of cryonics,” Robert C.W. Ettinger in 1976 as a means to preserve life at liquid nitrogen temperatures. It is hoped that as the future unveils newer and more sophisticated medical nanotechnology, people preserved by CI may be restored to youth and health. 1) Cryonic Preservation 7) Funding Programs Membership qualifies you to arrange and fund a vitrification Cryopreservation with CI can be funded through approved (anti-crystallization) perfusion and cooling upon legal death, life insurance policies issued in the USA or other countries. -
5 Ways to Deal with Anniversary Reactions What Do You Do When Anniversary Memories Are Anything but Silver Or Gold? Posted Sep 22, 2016
Psychology Today Ellen Hendriksen, Ph.D. Reprinted from Psychology Today September 22, 2016 5 Ways to Deal with Anniversary Reactions What do you do when anniversary memories are anything but silver or gold? Posted Sep 22, 2016 Anniversaries aren’t just for couples, and some aren’t so happy. The anniversary reaction: it’s the annual echo of a trauma or loss such as the death of a beloved, a nightmarish experience like sexual assault, a near-fatal accident, or military combat. Regardless of what happened, the anniversary reaction is specifically timed (hence the name), emotionally invested, and truly distressing. Moreover, it’s common; some researchers think the anniversary reaction should even be an official symptom of post-traumatic stress disorder. But despite the patterns being predictable, the reactions themselves are as varied as the individuals experiencing them. Sometimes, the mind remembers, even unconsciously, and a psychological reaction—like a spike in depression or PTSD—can be triggered by the weather, the light, or other seasonal reminders like back to school or the first signs of spring. For example, a study conducted by the Yale University School of Medicine looked at anniversary reactions in veterans of the early 1990s Gulf War. Several years after the war ended, each veteran, along with his or her spouse, was asked how well the veteran functioned over each of the previous 12 months. Each person identified the veteran’s worst month, best month, the month with the most PTSD symptoms, and the month with the fewest. Then, the researchers compared the veterans’ functioning to documented dates of their traumatic war experiences. -
The Transhumanist Reader Is an Important, Provocative Compendium Critically Exploring the History, Philosophy, and Ethics of Transhumanism
TH “We are in the process of upgrading the human species, so we might as well do it E Classical and Contemporary with deliberation and foresight. A good first step is this book, which collects the smartest thinking available concerning the inevitable conflicts, challenges and opportunities arising as we re-invent ourselves. It’s a core text for anyone making TRA Essays on the Science, the future.” —Kevin Kelly, Senior Maverick for Wired Technology, and Philosophy “Transhumanism has moved from a fringe concern to a mainstream academic movement with real intellectual credibility. This is a great taster of some of the best N of the Human Future emerging work. In the last 10 years, transhumanism has spread not as a religion but as a creative rational endeavor.” SHU —Julian Savulescu, Uehiro Chair in Practical Ethics, University of Oxford “The Transhumanist Reader is an important, provocative compendium critically exploring the history, philosophy, and ethics of transhumanism. The contributors anticipate crucial biopolitical, ecological and planetary implications of a radically technologically enhanced population.” M —Edward Keller, Director, Center for Transformative Media, Parsons The New School for Design A “This important book contains essays by many of the top thinkers in the field of transhumanism. It’s a must-read for anyone interested in the future of humankind.” N —Sonia Arrison, Best-selling author of 100 Plus: How The Coming Age of Longevity Will Change Everything IS The rapid pace of emerging technologies is playing an increasingly important role in T overcoming fundamental human limitations. The Transhumanist Reader presents the first authoritative and comprehensive survey of the origins and current state of transhumanist Re thinking regarding technology’s impact on the future of humanity. -
Nanorobot Construction Crews
Nanorobot Construction Crews Jaeseung Jeong, Ph.D Department of Bio and Brain engineering, KAIST Nanorobotics • Nanorobotics is the technology of creating machines or robots atltthit or close to the microscopi c scal lfe of a nanomet res (10-9 metres). More specifically, nanorobotics refers to the still largely ‘hypothetical’ nanotechnology engineering discipline of designing and building nanorobots. • Nanorobots ((,,nanobots, nanoids, nanites or nanonites ) would be typically devices ranging in size from 0.1-10 micrometers and constructed of nanoscale or molecular components. As no artificial non-biological nanorobots have yet been created, they remain a ‘hypothetical’ concept. • Another definition sometimes used is a robot which allows precision interactions with nanoscale objects , or can manipulate with nanoscale resolution. • Followingggpp this definition even a large apparatus such as an atomic force microscope can be considered a nanorobotic instrument when configured to perform nanomanipulation. • Also, macroscalble robots or mi crorob ots which can move wi th nanoscale precision can also be considered nanorobots. The T-1000 in Terminator 2: Judggyment Day • Since nanorobots would be microscopic in size , it would probably be necessary for very large numbers of them to work together to perform microscopic and macroscopic tasks. • These nanorobot swarms are fdifound in many sci ence fi fitiction stories, such as The T-1000 in Terminator 2: Judgment Day, nanomachine i n Meta l G ear So lid. • The word "nanobot" (also "nanite",,g, "nanogene", or "nanoant") is often used to indicate this fictional context and is a n info rma l o r eve n pejo rat ive term to refer to the engineering concept of nanorobots. -
Cryonics Magazine, Q1 1999
Mark Your Calendars Today! BioStasis 2000 June of the Year 2000 ave you ever considered Asilomar Conference Center Hwriting for publication? If not, let me warn you that it Northern California can be a masochistic pursuit. The simultaneous advent of the word processor and the onset of the Initial List Post-Literate Era have flooded every market with manuscripts, of Speakers: while severely diluting the aver- age quality of work. Most editors can’t keep up with the tsunami of amateurish submissions washing Eric Drexler, over their desks every day. They don’t have time to strain out the Ph.D. writers with potential, offer them personal advice, and help them to Ralph Merkle, develop their talents. The typical response is to search for familiar Ph.D. names and check cover letters for impressive credits, but shove ev- Robert Newport, ery other manuscript right back into its accompanying SASE. M.D. Despite these depressing ob- servations, please don’t give up hope! There are still venues where Watch the Alcor Phoenix as the beginning writer can go for details unfold! editorial attention and reader rec- Artwork by Tim Hubley ognition. Look to the small press — it won’t catapult you to the wealth and celebrity you wish, but it will give you a reason to practice, and it may even intro- duce you to an editor who will chat about your submissions. Where do you find this “small press?” The latest edition of Writ- ers’ Market will give you several possibilities, but let me suggest a more obvious and immediate place to start sending your work: Cryonics Magazine! 2 Cryonics • 1st Qtr, 1999 Letters to the Editor RE: “Hamburger Helpers” by Charles Platt, in his/her interest to go this route if the “Cryonics” magazine, 4th Quarter greater cost of insurance is more than offset Sincerely, 1998 by lower dues. -
Great Mambo Chicken and the Transhuman Condition
Tf Freewheel simply a tour « // o é Z oon" ‘ , c AUS Figas - 3 8 tion = ~ Conds : 8O man | S. | —§R Transhu : QO the Great Mambo Chicken and the Transhuman Condition Science Slightly Over the Edge ED REGIS A VV Addison-Wesley Publishing Company, Inc. - Reading, Massachusetts Menlo Park, California New York Don Mills, Ontario Wokingham, England Amsterdam Bonn Sydney Singapore Tokyo Madrid San Juan Paris Seoul Milan Mexico City Taipei Acknowledgmentof permissions granted to reprint previously published material appears on page 301. Manyofthe designations used by manufacturers andsellers to distinguish their products are claimed as trademarks. Where those designations appear in this book and Addison-Wesley was aware of a trademark claim, the designations have been printed in initial capital letters (e.g., Silly Putty). .Library of Congress Cataloging-in-Publication Data Regis, Edward, 1944— Great mambo chicken and the transhuman condition : science slightly over the edge / Ed Regis. p- cm. Includes bibliographical references. ISBN 0-201-09258-1 ISBN 0-201-56751-2 (pbk.) 1. Science—Miscellanea. 2. Engineering—Miscellanea. 3. Forecasting—Miscellanea. I. Title. Q173.R44 1990 500—dc20 90-382 CIP Copyright © 1990 by Ed Regis All rights reserved. No part ofthis publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording, or otherwise, without the prior written permission of the publisher. Printed in the United States of America. Text design by Joyce C. Weston Set in 11-point Galliard by DEKR Corporation, Woburn, MA - 12345678 9-MW-9594939291 Second printing, October 1990 First paperback printing, August 1991 For William Patrick Contents The Mania.. -
The Biochemistry of Cell Death Cell Death: Apoptosis and Other Means to an End, Second Edition by Douglas R
Zampieri et al. Cell Death and Disease (2020) 11:259 https://doi.org/10.1038/s41419-020-2465-5 Cell Death & Disease BOOK REVIEW Open Access The biochemistry of cell death Cell Death: Apoptosis and Other Means to an End, Second Edition by Douglas R. Green, St. Jude Children’s Research Hospital, Cold Spring Harbor Laboratory Press, New York, 2018 Carlotta Zampieri 1, Carlo Ganini 1 and Gerry Melino 1 Can we impress you with a mind-blowing revelation? Douglas Green is one of the worldwide leading experts “Cells are not eternal in our bodies, but rather they on apoptosis and cell death. He has dealt with the role of encounter death!”1. cell death in the regulation of cancer and immune If someone pronounces this sentence at a biology class, response, studying the molecular events that drive the students will laugh. Why? Because cell death has been process, focusing on the induction-activation of apoptosis studied since the 60s of the last century. When we speak in T cells and the role of Myc, death receptors and Bcl-2 about apoptosis nowadays, we regard it as a well-known in this context. His deep understanding of the field truth. Anyway, this truth did not catch the attention of allowed him to write the first edition of this book in a scientists until the 1980s, where the interest in the field clear and straightforward manner, enriched by extremely exploded, leading to a dramatic increase of publications. informative figures. His talent as a biologist, as well as a Cell death passed “from neglect to hysteria” in only a few communicator, has been condensed in this second edi- years, citing Martin Raff2, one of the founders of the field. -
Diffie and Hellman Receive 2015 Turing Award Rod Searcey/Stanford University
Diffie and Hellman Receive 2015 Turing Award Rod Searcey/Stanford University. Linda A. Cicero/Stanford News Service. Whitfield Diffie Martin E. Hellman ernment–private sector relations, and attracts billions of Whitfield Diffie, former chief security officer of Sun Mi- dollars in research and development,” said ACM President crosystems, and Martin E. Hellman, professor emeritus Alexander L. Wolf. “In 1976, Diffie and Hellman imagined of electrical engineering at Stanford University, have been a future where people would regularly communicate awarded the 2015 A. M. Turing Award of the Association through electronic networks and be vulnerable to having for Computing Machinery for their critical contributions their communications stolen or altered. Now, after nearly to modern cryptography. forty years, we see that their forecasts were remarkably Citation prescient.” The ability for two parties to use encryption to commu- “Public-key cryptography is fundamental for our indus- nicate privately over an otherwise insecure channel is try,” said Andrei Broder, Google Distinguished Scientist. fundamental for billions of people around the world. On “The ability to protect private data rests on protocols for a daily basis, individuals establish secure online connec- confirming an owner’s identity and for ensuring the integ- tions with banks, e-commerce sites, email servers, and the rity and confidentiality of communications. These widely cloud. Diffie and Hellman’s groundbreaking 1976 paper, used protocols were made possible through the ideas and “New Directions in Cryptography,” introduced the ideas of methods pioneered by Diffie and Hellman.” public-key cryptography and digital signatures, which are Cryptography is a practice that facilitates communi- the foundation for most regularly used security protocols cation between two parties so that the communication on the Internet today.