International Journal of Molecular Sciences Article Overexpression of Adiponectin Receptor 1 Inhibits Brown and Beige Adipose Tissue Activity in Mice Yu-Jen Chen 1,2,*, Chiao-Wei Lin 1,2, Yu-Ju Peng 2, Chao-Wei Huang 2 , Yi-Shan Chien 2, Tzu-Hsuan Huang 2, Pei-Xin Liao 2, Wen-Yuan Yang 2, Mei-Hui Wang 3, Harry J. Mersmann 2, Shinn-Chih Wu 1,2, Tai-Yuan Chuang 4, Yuan-Yu Lin 2,* , Wen-Hung Kuo 5,* and Shih-Torng Ding 1,2,* 1 Institute of Biotechnology, National Taiwan University, Taipei 10617, Taiwan;
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[email protected] (S.-T.D.); Tel.: +886-2-3366-4175 (S.-T.D.) Abstract: Adult humans and mice possess significant classical brown adipose tissues (BAT) and, upon cold-induction, acquire brown-like adipocytes in certain depots of white adipose tissues (WAT), known as beige adipose tissues or WAT browning/beiging.