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HOSPITALITY RX OPEN FORMULARY Prior Quantity Step Drug Class Drug Description Drug Name Tier Authorization Limit Therapy ADHD/ANTI‐NARCOLEPSY/ANTI‐OBESITY/ANOREXIANTS Amphetamine‐Dextroamphetamine Adderall Oral Tablet 10 MG Tier 3 MEDICAL DEVICES AND SUPPLIES Lancets 1st Choice Lancets Super Thin Miscellaneous Tier 2 MEDICAL DEVICES AND SUPPLIES Lancets 1st Choice Lancets Thin Miscellaneous Tier 2 MEDICAL DEVICES AND SUPPLIES Lancets 1st Choice Lancets Ultra Thin Miscellaneous Tier 2 MEDICAL DEVICES AND SUPPLIES Insulin Pen Needle 1st Tier Unifine Pentips Miscellaneous 29G X 12MM Tier 2 MEDICAL DEVICES AND SUPPLIES Insulin Pen Needle 1st Tier Unifine Pentips Miscellaneous 31G X 5 MM Tier 2 MEDICAL DEVICES AND SUPPLIES Insulin Pen Needle 1st Tier Unifine Pentips Miscellaneous 31G X 6 MM Tier 2 MEDICAL DEVICES AND SUPPLIES Insulin Pen Needle 1st Tier Unifine Pentips Miscellaneous 31G X 8 MM Tier 2 MEDICAL DEVICES AND SUPPLIES Insulin Pen Needle 1st Tier Unifine Pentips Miscellaneous 32G X 4 MM Tier 2 MEDICAL DEVICES AND SUPPLIES Insulin Pen Needle 1st Tier Unifine Pentips Plus Miscellaneous 29G X 12MM Tier 2 MEDICAL DEVICES AND SUPPLIES Insulin Pen Needle 1st Tier Unifine Pentips Plus Miscellaneous 31G X 5 MM Tier 2 MEDICAL DEVICES AND SUPPLIES Insulin Pen Needle 1st Tier Unifine Pentips Plus Miscellaneous 31G X 6 MM Tier 2 MEDICAL DEVICES AND SUPPLIES Insulin Pen Needle 1st Tier Unifine Pentips Plus Miscellaneous 31G X 8 MM Tier 2 MEDICAL DEVICES AND SUPPLIES Insulin Pen Needle 1st Tier Unifine Pentips Plus Miscellaneous 32G X 4 MM Tier 2 MEDICAL DEVICES AND SUPPLIES Lancets 1st Tier Unilet ComforTouch Miscellaneous Tier 2 CHEMICALS 2‐Deoxy‐D‐Glucose 2‐Deoxy‐D‐Glucose Powder Tier 3 CHEMICALS Hydroxytryptophan 5‐HTP Powder Tier 3 CHEMICALS Hydroxytryptophan 5‐Hydroxy‐L‐Tryptophan Powder Tier 3 CHEMICALS 5‐Methyltetrahydrofolate Calcium 5‐Methyltetrahydrofolate Calc Powder Tier 3 CHEMICALS 7‐Ketodehydroepiandrosterone (7‐Keto DHEA) 7‐Keto DHEA Powder Tier 3 DERMATOLOGICALS Methoxsalen 8‐Mop Oral Capsule 10 MG Tier 3 DERMATOLOGICALS Amantadine‐Amitriptyline‐Gabapentin‐Cyclobenzaprine A.A.G.C. Kit in TeroDerm External Cream 8‐4‐10‐4 % Tier 3 ANTIVIRALS Abacavir Sulfate Abacavir Sulfate Oral Tablet 300 MG Tier 1 x ANTIVIRALS Abacavir Sulfate‐Lamivudine‐Zidovudine Abacavir‐Lamivudine‐Zidovudine Oral Tablet 300‐150‐300 MG Tier 1 x HEMATOPOIETIC AGENTS Cyanocobalamin‐Methylcobalamin Abaneu‐SL Sublingual Tablet Sublingual 600‐600 MCG Tier 3 ANTIPSYCHOTICS/ANTIMANIC AGENTS Aripiprazole Abilify Maintena Intramuscular Suspension Reconstituted 300 MG Tier 3 xx ANTIPSYCHOTICS/ANTIMANIC AGENTS Aripiprazole Abilify Maintena Intramuscular Suspension Reconstituted 400 MG Tier 3 xx ANTIPSYCHOTICS/ANTIMANIC AGENTS Aripiprazole Abilify Oral Tablet 10 MG Tier 3 xx ANTIPSYCHOTICS/ANTIMANIC AGENTS Aripiprazole Abilify Oral Tablet 15 MG Tier 3 xx ANTIPSYCHOTICS/ANTIMANIC AGENTS Aripiprazole Abilify Oral Tablet 2 MG Tier 3 xx ANTIPSYCHOTICS/ANTIMANIC AGENTS Aripiprazole Abilify Oral Tablet 20 MG Tier 3 xx ANTIPSYCHOTICS/ANTIMANIC AGENTS Aripiprazole Abilify Oral Tablet 30 MG Tier 3 xx ANTIPSYCHOTICS/ANTIMANIC AGENTS Aripiprazole Abilify Oral Tablet 5 MG Tier 3 xx DIAGNOSTIC PRODUCTS Gadofosveset Trisodium Ablavar Intravenous Solution 244 MG/ML Tier 3 x ANALGESICS ‐ OPIOID Fentanyl Citrate Abstral Sublingual Tablet Sublingual 100 MCG Tier 3 x x ANALGESICS ‐ OPIOID Fentanyl Citrate Abstral Sublingual Tablet Sublingual 200 MCG Tier 3 x x ANALGESICS ‐ OPIOID Fentanyl Citrate Abstral Sublingual Tablet Sublingual 300 MCG Tier 3 x x ANALGESICS ‐ OPIOID Fentanyl Citrate Abstral Sublingual Tablet Sublingual 400 MCG Tier 3 x x ANALGESICS ‐ OPIOID Fentanyl Citrate Abstral Sublingual Tablet Sublingual 600 MCG Tier 3 x x ANALGESICS ‐ OPIOID Fentanyl Citrate Abstral Sublingual Tablet Sublingual 800 MCG Tier 3 x x CHEMICALS Saccharomyces Cerevisiae Extract AC Dermapeptide Liquid Tier 3 PSYCHOTHERAPEUTIC AND NEUROLOGICAL AGENTS ‐ MISC. Acamprosate Calcium Acamprosate Calcium Oral Tablet Delayed Release 333 MG Tier 1 x DERMATOLOGICALS Clindamycin Phosphate‐Benzoyl Peroxide Acanya External Gel 1.2‐2.5 % Tier 3 x ANTIDIABETICS Acarbose Acarbose Oral Tablet 100 MG Tier 1 ANTIDIABETICS Acarbose Acarbose Oral Tablet 25 MG Tier 1 ANTIDIABETICS Acarbose Acarbose Oral Tablet 50 MG Tier 1 ANTIASTHMATIC AND BRONCHODILATOR AGENTS Zafirlukast Accolate Oral Tablet 10 MG Tier 3 x ANTIASTHMATIC AND BRONCHODILATOR AGENTS Zafirlukast Accolate Oral Tablet 20 MG Tier 3 x DIAGNOSTIC PRODUCTS Glucose Blood Accu‐Chek Active In Vitro Strip Tier 2 DIAGNOSTIC PRODUCTS Glucose Blood Accu‐Chek Aviva In Vitro Strip Tier 2 DIAGNOSTIC PRODUCTS Glucose Blood Accu‐Chek Aviva Plus In Vitro Strip Tier 2 DIAGNOSTIC PRODUCTS Glucose Blood Accu‐Chek Compact Plus In Vitro Strip Tier 2 MEDICAL DEVICES AND SUPPLIES Lancets Accu‐Chek FastClix Lancets Miscellaneous Tier 2 MEDICAL DEVICES AND SUPPLIES Lancets Accu‐Chek Multiclix Lancets Miscellaneous Tier 2 MEDICAL DEVICES AND SUPPLIES Blood Glucose Monitoring Supplies Accu‐Chek Nano SmartView Kit w/Device Tier 2 MEDICAL DEVICES AND SUPPLIES Lancets Accu‐Chek Safe‐T Pro Lancets Miscellaneous Tier 2 DIAGNOSTIC PRODUCTS Glucose Blood Accu‐Chek SmartView In Vitro Strip Tier 2 MEDICAL DEVICES AND SUPPLIES Lancets Accu‐Chek Soft Touch Lancets Miscellaneous Tier 2 MEDICAL DEVICES AND SUPPLIES Lancets Accu‐Chek Softclix Lancets Miscellaneous Tier 2 MEDICAL DEVICES AND SUPPLIES Blood Glucose Monitoring Supplies Accu‐Chek Voicemate Kit Tier 2 ANTIHYPERTENSIVES Quinapril HCl Accupril Oral Tablet 10 MG Tier 3 ANTIHYPERTENSIVES Quinapril HCl Accupril Oral Tablet 20 MG Tier 3 ANTIHYPERTENSIVES Quinapril HCl Accupril Oral Tablet 40 MG Tier 3 ANTIHYPERTENSIVES Quinapril HCl Accupril Oral Tablet 5 MG Tier 3 ANTIHYPERTENSIVES Quinapril‐Hydrochlorothiazide Accuretic Oral Tablet 10‐12.5 MG Tier 3 ANTIHYPERTENSIVES Quinapril‐Hydrochlorothiazide Accuretic Oral Tablet 20‐12.5 MG Tier 3 ANTIHYPERTENSIVES Quinapril‐Hydrochlorothiazide Accuretic Oral Tablet 20‐25 MG Tier 3 DIAGNOSTIC PRODUCTS Glucose Blood Accutrend Glucose In Vitro Strip Tier 2 BETA BLOCKERS Acebutolol HCl Acebutolol HCl Oral Capsule 200 MG Tier 1 BETA BLOCKERS Acebutolol HCl Acebutolol HCl Oral Capsule 400 MG Tier 1 ANTIHYPERTENSIVES Perindopril Erbumine Aceon Oral Tablet 4 MG Tier 3 ANTIHYPERTENSIVES Perindopril Erbumine Aceon Oral Tablet 8 MG Tier 3 ANTIDOTES Acetylcysteine (Antidote) Acetadote Intravenous Solution 200 MG/ML Tier 3 x ANALGESICS ‐ OPIOID Acetaminophen w/ Codeine Acetaminophen‐Codeine #2 Oral Tablet 300‐15 MG Tier 1 ANALGESICS ‐ OPIOID Acetaminophen w/ Codeine Acetaminophen‐Codeine #3 Oral Tablet 300‐30 MG Tier 1 ANALGESICS ‐ OPIOID Acetaminophen w/ Codeine Acetaminophen‐Codeine #4 Oral Tablet 300‐60 MG Tier 1 ANALGESICS ‐ OPIOID Acetaminophen w/ Codeine Acetaminophen‐Codeine Oral Solution 120‐12 MG/5ML Tier 1 ANALGESICS ‐ OPIOID Acetaminophen w/ Codeine Acetaminophen‐Codeine Oral Tablet 300‐15 MG Tier 1 ANALGESICS ‐ OPIOID Acetaminophen w/ Codeine Acetaminophen‐Codeine Oral Tablet 300‐30 MG Tier 1 ANALGESICS ‐ OPIOID Acetaminophen w/ Codeine Acetaminophen‐Codeine Oral Tablet 300‐60 MG Tier 1 OTIC AGENTS Hydrocortisone w/Acetic Acid Acetasol HC Otic Solution 2‐1 % Tier 1 DIURETICS Acetazolamide AcetaZOLAMIDE ER Oral Capsule Extended Release 12 Hour 500 MG Tier 1 DIURETICS Acetazolamide AcetaZOLAMIDE Oral Tablet 125 MG Tier 2 DIURETICS Acetazolamide AcetaZOLAMIDE Oral Tablet 250 MG Tier 1 DIURETICS Acetazolamide Sodium AcetaZOLAMIDE Sodium Injection Solution Reconstituted 500 MG Tier 1 x GENITOURINARY AGENTS ‐ MISCELLANEOUS Acetic Acid Acetic Acid Irrigation Solution 0.25 % Tier 1 OTIC AGENTS Acetic Acid (Otic) Acetic Acid Otic Solution 2 % Tier 1 OTIC AGENTS Acetic Acid‐Aluminum Acetate Acetic Acid‐Aluminum Acetate Otic Solution 2 % Tier 2 CHEMICALS Acetone Acetone Solution Tier 3 ANALGESICS ‐ NonNarcotic Aspirin Acetyl Salicylic Acid Powder Tier 3 COUGH/COLD/ALLERGY Acetylcysteine Acetylcysteine Inhalation Solution 10 % Tier 1 COUGH/COLD/ALLERGY Acetylcysteine Acetylcysteine Inhalation Solution 20 % Tier 1 ANTIDOTES Acetylcysteine (Antidote) Acetylcysteine Intravenous Solution 200 MG/ML Tier 1 x COUGH/COLD/ALLERGY Acetylcysteine Acetylcysteine Powder Tier 3 CHEMICALS Acetyl‐D‐Glucosamine Acetyl‐D‐Glucosamine Powder Tier 3 CHEMICALS Lactobacillus Acidophilus Acidophilus Lactobacillus Powder Tier 3 ULCER DRUGS Rabeprazole Sodium Aciphex Oral Tablet Delayed Release 20 MG Tier 3 x x ULCER DRUGS Rabeprazole Sodium AcipHex Sprinkle Oral Capsule Sprinkle 10 MG Tier 3 x x ULCER DRUGS Rabeprazole Sodium AcipHex Sprinkle Oral Capsule Sprinkle 5 MG Tier 3 x x DERMATOLOGICALS Acitretin Acitretin Oral Capsule 10 MG Tier 1 DERMATOLOGICALS Acitretin Acitretin Oral Capsule 17.5 MG Tier 1 DERMATOLOGICALS Acitretin Acitretin Oral Capsule 25 MG Tier 1 DERMATOLOGICALS Alclometasone Dipropionate Aclovate External Cream 0.05 % Tier 3 DERMATOLOGICALS Benzoyl Peroxide Acne Medication 5 External Gel 5 % Tier 1 BIOLOGICALS MISC Acremonium Acremonium Subcutaneous Solution 20000 PNU/ML Tier 3 x ANALGESICS ‐ ANTI‐INFLAMMATORY Tocilizumab Actemra Subcutaneous Solution Prefilled Syringe 162 MG/0.9ML Tier 2 x ENDOCRINE AND METABOLIC AGENTS ‐ MISC. Corticotropin Acthar HP Injection Gel 80 UNIT/ML Tier 2 x VACCINES Haemophilus B Polysac Conj Vac ActHIB Intramuscular Solution Reconstituted Tier 3 x DERMATOLOGICALS Permethrin Acticin External Cream 5 % Tier 1 TETRACYCLINES Doxycycline Hyclate Acticlate Oral Tablet 150 MG Tier 3 x TETRACYCLINES Doxycycline Hyclate Acticlate Oral Tablet 75 MG Tier 3 x DERMATOLOGICALS Silver Acticoat
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  • Amino Acid Catalyzed Direct Asymmetric Aldol Reactions: a Bioorganic Approach to Catalytic Asymmetric Carbon-Carbon Bond-Forming Reactions

    Amino Acid Catalyzed Direct Asymmetric Aldol Reactions: a Bioorganic Approach to Catalytic Asymmetric Carbon-Carbon Bond-Forming Reactions

    5260 J. Am. Chem. Soc. 2001, 123, 5260-5267 Amino Acid Catalyzed Direct Asymmetric Aldol Reactions: A Bioorganic Approach to Catalytic Asymmetric Carbon-Carbon Bond-Forming Reactions Kandasamy Sakthivel, Wolfgang Notz, Tommy Bui, and Carlos F. Barbas III* Contribution from The Skaggs Institute for Chemical Biology and the Department of Molecular Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037 ReceiVed January 3, 2001 Abstract: Direct asymmetric catalytic aldol reactions have been successfully performed using aldehydes and unmodified ketones together with commercially available chiral cyclic secondary amines as catalysts. Structure- based catalyst screening identified L-proline and 5,5-dimethyl thiazolidinium-4-carboxylate (DMTC) as the most powerful amino acid catalysts for the reaction of both acyclic and cyclic ketones as aldol donors with aromatic and aliphatic aldehydes to afford the corresponding aldol products with high regio-, diastereo-, and enantioselectivities. Reactions employing hydroxyacetone as an aldol donor provide anti-1,2-diols as the major product with ee values up to >99%. The reactions are assumed to proceed via a metal-free Zimmerman- Traxler-type transition state and involve an enamine intermediate. The observed stereochemistry of the products is in accordance with the proposed transition state. Further supporting evidence is provided by the lack of nonlinear effects. The reactions tolerate a small amount of water (<4 vol %), do not require inert reaction conditions and preformed enolate equivalents, and can be conveniently performed at room temperature in various solvents. In addition, reaction conditions that facilitate catalyst recovery as well as immobilization are described. Finally, mechanistically related addition reactions such as ketone additions to imines (Mannich- type reactions) and to nitro-olefins and R,â-unsaturated diesters (Michael-type reactions) have also been developed.
  • Proline- and Alanine-Rich N-Terminal Extension of the Basic Bovine P-Crystallin B1 Chains

    Proline- and Alanine-Rich N-Terminal Extension of the Basic Bovine P-Crystallin B1 Chains

    CORE Metadata, citation and similar papers at core.ac.uk Provided by Elsevier - Publisher Connector Volume 161, number 2 FEBS 0790 September 1983 Proline- and alanine-rich N-terminal extension of the basic bovine P-crystallin B1 chains G.A.M. Berbers, W.A. Hoekman, H. Bloemendal, W.W. de Jong, T. Kleinschmidt* and G. Braunitzer* Laboratorium voor Biochemie, Universiteit van Nijmegen, Geert Grooteplein Noord 21, 6525 EZ Nijmegen, The Netherlands and *Max-Planck-Institut ft’ir Biochemie, Abteilung Proteinchemie, D-8033 Martinsried bei Miinchen, FRG Received 22 June 1983 The amino acid sequence of the N-terminal region of the two basic bovine &crystallin B1 chains has been analyzed. The results reveal that @Bibis derived in vivo from the primary gene product @la by removal of a short N-terminal sequence. It appears that them1 chains have the same domain structure as observed in other /3- and y-crystallin chains. They have, however, a very long N-terminal extension in comparison with other &chains. This extension is mainly composed of a remarkable Pro- and Ala-rich sequence, which suggests an interaction of these structural proteins with the cytoskeleton and/or the plasma membranes of the lens cells. Protein sequence Bovine &crystallin N-terminal extension Proline- and aianine-rich Domain structure 1. INTRODUCTION 33 000 and 31000, respectively, are characteristic for fltikt, [ 111. ,8Fha is a primary gene product, from The crystallins are evolutionary highly conserv- which ,8&b arises by post-translational modifica- ed structural eye lens proteins, which can be divid; tion [lo-121, most probably a proteolytic step ed into 4 classes: (Y-,,&, y- and t-crystallin [ 11.