The Extra-Oral Approach to the Ascending Ramus Is Difficult Owing to the Proximity of the Facial Nerve
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Pancreatic Organotherapy for Diabetes, 1889-1921
Medical History, 1995, 39: 288-316 Pancreatic Organotherapy for Diabetes, 1889-1921 ROBERT TATTERSALL* Introduction The isolation of insulin by Banting and Best in 1921 and its rapid commercial exploitation revolutionized the treatment of diabetes. The story, frequently told as a romance of medicine, is that a young orthopaedic surgeon, Frederick Banting, went to the local Professor of Physiology, J J R Macleod, asking for facilities to try to isolate the internal secretion of the pancreas. Macleod was sceptical but provided a lab, dogs and a student assistant to measure blood sugar. After only three months, Banting and Charles Best isolated a potent anti-diabetic substance which was first used on a human diabetic in January 1922. Controversy followed when Banting and Macleod, not Banting and Best, were awarded the 1923 Nobel Prize. Much has been written about the events in Toronto in 1921-1922l as well as about the priority disputes which followed.2 Two editorials in the Lancet in 1923 questioned why this discovery had taken so long.3 The seductively simple critique ran as follows: in 1869, Paul Langerhans described his eponymous islands, in 1889 Oskar Minkowski produced severe diabetes in dogs by pancreatectomy, in 1891 George Murray cured myxoedema by injections of thyroid extract and in 1893 Gustave-Edouard Laguesse suggested that the islands of Langerhans produced "an endocrine secretion" which controlled carbohydrate metabolism. How could it have taken thirty years for therapeutics to exploit the physiological suggestion? The origins of the hormone concept and the history of organotherapy in general have been explored in detail by Merriley Borell.4 Her work focuses on the role of physiologists, *Professor Robert Tattersall, Diabetes Unit, 1954, 9: 281-9, and W R Feasby, 'The discovery of University Hospital, Nottingham NG7 2UH. -
College News Sir Victor Ewings Negus
College news 201 IN MEMORIAM Sir Victor Ewings Negus at an early stage in his career, but at that time >,rm~s only intense personal drive could create the neces- sary conditions to make this possible. The Mechan- ism of the Larynx is a classic piece of research and is still the standard reference book of the world. In 1937 he assisted St Clair Thomson in the preparation of the fourth edition of Diseases of the Nose and Throat, which has been for many years the standard textbook in English on this sub- ject. The fifth and sixth editions were entirely his, and he brought them completely up to date. The language was lucid and concise and very readable. This textbook was his only major publication in clinical otolaryngology, but he had many publica- tions outside the field of clinical surgery. In the basic sciences he published books on The Compara- tive Anatomy and Physiology of the Larynx in 1949, The Comparative Anatomy of the Nose and Accessory Sinuses in 1958, and The Biology of Respiration in I965. The theories expounded in these books were developed and supported by his own laboratory investigations carried out in the Ferens Institute at the Middlesex Hospital and in the Royal College of Surgeons after he had retired from clinical practice at King's College Hospital. When the Council of the Royal College of Sur- geons, under the presidency of Lord Webb-Johnson, decided to co-opt to Council representatives of specialist branches of surgery Victor Negus was the first co-opted member for otolaryngology. -
Annals of the Royal College of Surgeons Ofengland
Annals ofthe Royal College of Surgeons ofEngland ,Editor A J Harding Rains MS FRCS Assistant Editor R M Kirk MS FRCS Associate Editors J E Riding MD FFARCS representing the Faculty of Anaesthetists, and K P Liddelow FDSRCS FDSRCSEd representing the Faculty of Dental Surgery Executive Editor (British Medical Association) D I Crowther BM Bch MRCS LRCP Published by the Royal College of Surgeons of England in conjunction with the Journal Department of' the British Medical Association B.M.A. House Tavistock Square, London WC iH 9JR Copyright ©) 1975 by the Annals of the Royal College of Surgeons of England. All rights of reproduction are reserved in respect of all papers, articles, tables and illustrationis, etc., published in this journal in all countries of the world. Printed by Dorriston Ltd., 21/25 Earl Street, London EC2A 2HY Subscription rates, United Kingdom and Ireland £1o per annum post free. Overseas ixi (US $28.25) per annum post free. Back numbers Li.25 per copy post free. All enquiries concerning subscriptions and sales should be addressed to the Subscription Manager, Annals of the Royal College of Surgeons, BMA House, Tavistock Square, London WCiH 9JR. Authors wishing to submit original scientific papers for publication, other thani those giving statutory and postgraduate lectures, are requested to write in the first instance to the Editor at the College. College address for correspondence College facilities Royal College of Surgeons of England, Lincoln's Users of College facilities: Those eligible in- Inn Fields, 'London WC2A 3PN. Telephone oi- clude Fellows, Members, aivid other Diplomates, 405 3474. Telegrams: Collsurg, Holb, London. -
Sam Goldstein Dana Princiotta Jack A. Naglieri Editors Evolutionary
Sam Goldstein Dana Princiotta Jack A. Naglieri Editors Handbook of Intelligence Evolutionary Theory, Historical Perspective, and Current Concepts Sam Goldstein • Dana Princiotta Jack A. Naglieri Editors Handbook of Intelligence Evolutionary Theory, Historical Perspective, and Current Concepts 2015 This volume is dedicated to the thousands of children to whom I have administered IQ tests and from whom I have learned that life is far more complex than a set of scores. To the researchers and clinicians who have come before and will follow me in the future. Science is never easy and not always popular but all we have to manage and temper our extraordinary and frequently expansive beliefs; and to Sherrie, my wonderful wife and partner. Sam Goldstein I am eternally grateful to my mother, Alison Helen Princiotta , for her extraordinary combination of love and wisdom; to my partner, Paul Alexander Brighton , for his unrelenting optimism and devotion; and to my nephews, Tyler James and Hunter James , for their collective enrichment of my life, coursing from New York all the way to “Oootah” (Utah). Dana Princiotta This book is dedicated to my wife, Kathleen Kryza, with love and admiration. Jack A. Naglieri “I believe in intuition and inspiration. Imagination is more important than knowl- edge. For knowledge is limited, whereas imagination embraces the entire world, stimulating progress, giving birth to evolution. It is, strictly speaking, a real factor in scientifi c research.” Albert Einstein “Man’s mind, once stretched by a new idea, never regains its original dimensions.” Oliver Wendell Holmes, Sr. “It is not the strongest or the most intelligent who will survive but those who can best manage change.” Charles Darwin vii Editor Biographies Sam Goldstein, Ph.D. -
Passchendaele Remembered
1917-2017 PASSCHENDAELE REMEMBERED CE AR NT W E T N A A E R R Y G THE JOURNAL OF THE WESTERN FRONT ASSOCIATION FOUNDED 1980 JUNE/JULY 2017 NUMBER 109 2 014-2018 www.westernfrontassociation.com With one of the UK’s most established and highly-regarded departments of War Studies, the University of Wolverhampton is recruiting for its part-time, campus based MA in the History of Britain and the First World War. With an emphasis on high-quality teaching in a friendly and supportive environment, the course is taught by an international team of critically-acclaimed historians, led by WFA Vice-President Professor Gary Sheffield and including WFA President Professor Peter Simkins; WFA Vice-President Professor John Bourne; Professor Stephen Badsey; Dr Spencer Jones; and Professor John Buckley. This is the strongest cluster of scholars specialising in the military history of the First World War to be found in any conventional UK university. The MA is broadly-based with study of the Western Front its core. Other theatres such as Gallipoli and Palestine are also covered, as is strategy, the War at Sea, the War in the Air and the Home Front. We also offer the following part-time MAs in: • Second World War Studies: Conflict, Societies, Holocaust (campus based) • Military History by distance learning (fully-online) For more information, please visit: www.wlv.ac.uk/pghistory Call +44 (0)1902 321 081 Email: [email protected] Postgraduate loans and loyalty discounts may also be available. If you would like to arrange an informal discussion about the MA in the History of Britain and the First World War, please email the Course Leader, Professor Gary Sheffield: [email protected] Do you collect WW1 Crested China? The Western Front Association (Durham Branch) 1917-2017 First World War Centenary Conference & Exhibition Saturday 14 October 2017 Cornerstones, Chester-le-Street Methodist Church, North Burns, Chester-le-Street DH3 3TF 09:30-16:30 (doors open 09:00) Tickets £25 (includes tea/coffee, buffet lunch) Tel No. -
Anaesthesia for Minimally Invasive Surgery
ANAESTHESIA FOR MINIMALLY INVASIVE SURGERY ANAESTHESIA FOR MINIMALLY INVASIVE SURGERY By Thomas Allen Crozier PUBLISHED BY THE PRESS SYNDICATE OF THE UNIVERSITY OF CAMBRIDGE The Pitt Building, Trumpington Street, Cambridge, United Kingdom CAMBRIDGE UNIVERSITY PRESS The Edinburgh Building, Cambridge CB2 2RU, UK 40 West 20th Street, New York, NY 10011-4211, USA 477 Williamstown Road, Port Melbourne, VIC 3207, Australia Ruiz de Alarcón 13, 28014 Madrid, Spain Dock House, The Waterfront, Cape Town 8001, South Africa http://www.cambridge.org © Cambridge University Press 2004 This book is in copyright. Subject to statutory exception and to the provisions of relevant collective licensing agreements, no reproduction of any part may take place without the written permission of Cambridge University Press. First published 2004 Printed in the United Kingdom at the University Press, Cambridge Typeface: Ehrhardt 10/11pt System: QuarkXpress® A catalog record for this book is available from the British Library Library of Congress Cataloging in Publication data ISBN 1 841 10191 5 The publisher has used its best endeavors to ensure that the URLs for external websites referred to in this book are correct and active at the time of going to press. However, the publisher has no responsibility for the websites and can make no guarantee that a site will remain live or that the content is or will remain appropriate. Every effort has been made in preparing this book to provide accurate and up-to-date information that is in accord with accepted standards and practice at the time of publication. Nevertheless, the authors, editors and publisher can make no warranties that the information contained herein is totally free from error, not least because clinical standards are constantly changing through research and regulation. -
Explore the Index
Index Compiled by the author A Frenchman in Khaki (Paul Maze): Churchill's Adenauer, Dr Konrad-continued introduction to, 1288 n.1 near', 844; and 'friendly messages', 849, 856; A Gunfor Sale (Graham Greene): 1310 and a proposed Four-Power conference (at A History ofthe English-Speaking Peoples (Winston Berlin), 92g-30; to be supported, 1003; and S. Churchill, 4 volumes, 1956-8): Churchill's Churchill's desire for a Summit with the work on, 177, 180, 255, 274, 847 n.2, 876-7, Soviets, IOI 3; 'desultory discussion' about, 883-4,887,891,915,958,1044,1066,1077-8; 104 7; and the French rejection of the Euro Churchill renews work on, I 126, I 132, I 136, pean Defence Community, 1055-6; French 1141,1144,1145-6,1148-g,1161,1162,1163, 'harshness' to, 105 7; Churchill 'high on the 1165, 1166, 1173, 1174, 1175, 1176, 1177-8, list' of admirers of, 1075; and a possible 1179; the first v9lume published, 1183-4, Paris meeting, 1103; unwell, 1168; Churchill 1193, I 196-7; continuing work on, I 187, meets (in Bonn), 1197; Churchill meets (in 1188, 118g-go, 1190, 1200, 1201, 1205, London), 1306; a gift from, 1307 1212-13, 1214; the second volume published, Adler, Generaljulius Ochs: 327, 684, 685 1223, 1225; 'rapidly nearing completion', Admiralty House (Whitehall): 1330 1228, 122g-30, 1233, 1241; the third Adrian, Baron: 1263 n.2 volume published, 1249-50, 1254; the Adriatic Sea: 6, 16, 200, 238, 239 fourth volume published, 1267 Aegean Sea: 91, 332 A Passage to India (E. -
Belly-Rippers, Surgical Innovation and the Ovariotomy Controversy Sally Frampton Faculty of English University of Oxford Oxford, UK
medicine and biomedical sciences in modern history sciences modern in biomedical and medicine BELLY-RIPPERS, SURGICAL INNOVATION AND THE OVARIOTOMY CONTROVERSY SALLY FRAMPTON Medicine and Biomedical Sciences in Modern History Series Editors Carsten Timmermann University of Manchester Manchester, UK Michael Worboys University of Manchester Manchester, UK The aim of this series is to illuminate the development and impact of medicine and the biomedical sciences in the modern era. The series was founded by the late Professor John Pickstone, and its ambitions refect his commitment to the integrated study of medicine, science and tech- nology in their contexts. He repeatedly commented that it was a pity that the foundation discipline of the feld, for which he popularized the acronym ‘HSTM’ (History of Science, Technology and Medicine) had been the history of science rather than the history of medicine. His point was that historians of science had too often focused just on scientifc ideas and institutions, while historians of medicine always had to consider the understanding, management and meanings of diseases in their socio-economic, cultural, technological and political contexts. In the event, most of the books in the series dealt with medicine and the biomedical sciences, and the changed series title refects this. However, as the new editors we share Professor Pickstone’s enthusiasm for the inte- grated study of medicine, science and technology, encouraging studies on biomedical science, translational medicine, clinical practice, disease histories, medical technologies, medical specialisms and health policies. The books in this series will present medicine and biomedical science as crucial features of modern culture, analysing their economic, social and political aspects, while not neglecting their expert content and con- text. -
Frazer's Anatomy Criticism but Is Intended to Enhance the Value and Biology
1536 25 December 1965 Book Reviews JOURNAL for ever of the opportunity to study selective general application as part of the subject corned by teachers and students alike. The processes which are likely to be similar to matter of human population genetics. We are rewriting of the first chapter has greatly those which affected our own ancestors at thus enabled to form a picture of the two improved the book, as has the inclusion of one of the most important stages of their and interacting processes: the elaboration of new references to recent work on the development, our physical revolution. proteins at the molecular level, and their structure, and blood supply of bone. It is The papers on cell genetics probe deeply spread through or elimination from the appreciated that the author has endeavoured into the biochemistry of cells undergoing population by natural selection. to preserve the essential character of the book reproduction, and are individually excellent, as set out by Frazer. Nevertheless the time but they stand somewhat apart from the rest A. E. MOURANT. has come when some of the more sketchy of the symposium. Perhaps for that reason illustrations-for example, Figs. 28, 32, 106, it was good that the collection should have 149, 155, and 171-could with profit be included them and so helped towards replaced by more realistic ones. This sug- integrating this fundamental work with the gestion should not be taken as a carping main streams of research in human genetics Frazer's Anatomy criticism but is intended to enhance the value and biology. -
Surgical Spirit a Newsletter for and by Volunteers at the Royal College of Surgeons
Surgical Spirit A newsletter for and by Volunteers at the Royal College of Surgeons Issue 18, Summer 2013 1 Front Cover : A photograph of David Tompsett at work (RCSSC/ph 00180). In the 1960s conservator David Tompsett made a large series of corrosion casts of mammalian organs. These casts are made when resin is injected into the soft tissues of an organ and left to set. The body part is then bathed in acid to disintegrate the surrounding tissues. The result is an intricate resin cast. The cast on the front cover shows a pair of lungs. 2 Welcome to this summer edition of Surgical Spirit , which mainly revolves around a series of successes for our Museums and Archives department, such as designation status for our collections; the staging of an event with a difference; funding for our ‘War, Art and Surgery’ programme in 2014. Many snippets also include the news about the Hunterian Museum featuring in The Times and the FT Weekend Magazine ; The Hunterian Bicentenary Fellowship award; and catering discounts available for our helpers. Our own volunteers’ contributions in this issue make us re-live our recent day out and the experience of visiting the College and the Hunterian Museum from an artist’s point of view; while the curatorial focus is on a recently re-displayed museum case and the completion of the latest Wellcome Museum of Anatomy and Pathology project. Once again in this edition there are plenty of team changes relating to both staff and volunteers. Last but not least an exciting series of events lies ahead throughout the summer and autumn (please note that events which already happened in July and August are not listed). -
Cruise Med Norwegian Sun – September 2012
Cruise med Norwegian Sun – september 2012 Dagbog fra en dejlig cruiseferie i Nordsøen og Atlanterhavet Søndag d. 16. september: Vi fik pakket kufferterne færdig om formiddagen, sat urtepotterne i vand og var klar til afgang kl. 12. Forinden var vi begge på vægten, så vi kan se hvordan 2 ugers cruise indvirker. Der kom mail fra Rikke med link til en dejlig video fra vores familiecruise i Middelhavet i sommer. Der var telefon fra Thomas, Rikke og Lissa med gode ønsker for rejsen, og Steen & Karin og Lissy & Gert sendte mail og ønskede god tur. Michael kørte os til Frihavnen, og indchekningen på Norwegian Sun gik meget hurtigt og enkelt. Vi fik vores ”stateroom”, og gik derefter op på 11. sal og fik BBQ frokost ved poolside. Det var salat og grillet kylling, og kun Karin fik is til dessert. Vi var derefter på rundtur og se alle skibets faciliteter. Der var redningsøvelse på dæk 6 en halv time før afsejling, og kl. 17 afgik skibet, og vi var tilskuere til noget underholdning med musik og dans på dæk. 9. KL. 18 gik vi til restaurant Seven Seas og fik et bord til 2. Vi syntes godt om lokalet, den høflige betjening og maden. Karin fik laksetartar, svinemedaljon og norsk cheesecake, og jeg valgte caesar salad og grillet kyllingebryst og ingen dessert. Der blev serveret isvand, og vi holdt os fra vin. Vi slentrede derefter igen lidt rundt, og jeg skrev lidt på dagbogen, inden vi kl. 21 gik til Stardust teatret og så dagens show. Den kvindelige canadiske cruise director Jamie var meget veltalende og underholdende, et par der fejrede 60 års bryllupsdag fik en flaske champagne, en række senior officerer blev præsenteret, et ensemble på 14 unge personer dansede og sang, og en herrekvartet fremførte med succes en række sange på italiensk og engelsk bl.a. -
Mr. Keats, Are to Be Congratulated Upon the Complete After
1060 Messrs. Le Brasseur and Oakley for the London and and dissertations must be delivered at the College not later than 4 o’clock P.M. on Dec. 1914. Counties Medical Protection Society, on Thursday, 31st, appeared The first award of the Sir Gilbert Blane medal under the behalf of the plaintiff, and the society, as well as revised regulations was made to Surgeon G. F. Syms, R.N. Mr. are to be the Keats, congratulated upon complete The financial statement shows that the gross income of the vindication of the latter’s character thus achieved College, exclusive of the income from trust funds, amounted after prolonged litigation. to .626,833, an increase of Z819 on the amount for the previous year, while the expenditure in respect of revenue amounted to .621,425, a decrease of .6836 on the previous in connexion with ROYAL COLLEGE OF SURGEONS OF year. The receipts and expenses the trust funds are placed this year in a separate account. ENGLAND. While it is evident that the College is in a good financial position at the present time the Council consider that ANNUAL REPORT OF THE COUNCIL. it is most important to add to its invested funds for THE annual report of the Council of the College, which is several reasons. Among these may be mentioned: (1) the to be presented to the annual meeting of Fellows and insecurity of the income derived from examination and the continued increase in rates and Members on Thursday, Nov. 19th, has now been published, diploma fees ; (2) taxes; the of the museum and and and contains a record of the work accomplished by the (3) growth library consequent increase in cost of the in College in its various departments during the year ending upkeep ; (4) probability that, course of it will become to make extensive August lst, 1914.