Conf. Dr. Ing. Daniel-Ioan HĂDĂRUGĂ

Lista de lucrări

Lista celor mai relevante 10 lucrări ştiinţifice publicate

1. Hădărugă, N.G.; Bandur, G.N.; David, I.; Hădărugă, D.I.*, A review on thermal analyses of cyclodextrins and cyclodextrin complexes, Environmental Chemistry Letters 2019, 17, 349-373, ISSN 1610-3653, https://doi.org/10.1007/s10311-018-0806-8 (ISI 4.617 (2018) / Q1) 2. Hădărugă, N.G.; Szakal, R.N.; Chirilă, C.A.; Lukinich-Gruia, A.T.; Păunescu, V.; Muntean, C.; Rusu, G.; Bujancă, G.; Hădărugă, D.I., Complexation of Danube common nase (Chondrostoma nasus L.) oil by β-cyclodextrin and 2-hydroxypropyl-β-cyclodextrin, Food Chemistry 2020, 303, art. 125419, ISSN 0308-8146, https://doi.org/10.1016/j.foodchem.2019.125419 (ISI 5.399 / Q1) 3. Hădărugă, D.I.; Birău (Mitroi), C.L.; Gruia, A.T.; Păunescu, V.; Bandur, G.N.; Hădărugă, N.G., Moisture evaluation of β-cyclodextrin/fish oils complexes by thermal analyses: A data review on common barbel (Barbus barbus L.), Pontic shad (Alosa immaculata Bennett), European wels catfish (Silurus glanis L.), and common bleak (Alburnus alburnus L.) living in Danube river, Food Chemistry 2017, 236, 49-58, ISSN 0308-8146, https://doi.org/10.1016/j.foodchem.2017.03.093 (ISI 4.946/ ISI(2018) = 5.399/Q1) 4. Hădărugă, D.I.*; Costescu, C.I.; Corpaş, L.; Hădărugă, N.G.; Isengard, H.-D., Differentiation of rye and wheat flour as well as mixtures by using the kinetics of Karl Fischer water titration, Food Chemistry 2016, 195, 49-55, ISSN 0308-8146, https://doi.org/10.1016/j.foodchem.2015.08.124 (ISI 4.529/ ISI(2018) = 5.399/Q1). 5. Ünlüsayin, M.; Hădărugă, N.G.; Rusu, G.; Gruia, A.T.; Păunescu, V.; Hădărugă, D.I.*, Nano- encapsulation competitiveness of omega-3 fatty acids and correlations of thermal analysis and Karl Fischer water titration for European anchovy (Engraulis encrasicolus L.) oil / β-cyclodextrin complexes, LWT – Food Science and Technology 2016, 68, 135-144, ISSN 0023-6438, https://doi.org/10.1016/j.lwt.2015.12.017, (ISI 2.329/ ISI(2018) = 3.714/Q1) 6. Hădărugă, D.I.*; Ünlüsayin, M.; Gruia, A.T.; Birău (Mitroi), C.; Rusu, G.; Hădărugă, N.G., Thermal and oxidative stability of Atlantic salmon oil (Salmo salar L.) and complexation with β-cyclodextrin, Beilstein Journal of Organic Chemistry 2016, 12, 179-191, ISSN 1860-5397, https://doi.org/10.3762/bjoc.12.20 (ISI 2.337/ ISI(2018) = 2.595/Q2). 7. Hădărugă, D.I.*; Hădărugă, N.G.; Costescu, C.I.; David, I.; Gruia, A.T., Thermal and oxidative stability of the Ocimum basilicum L. essential oil/β-cyclodextrin supramolecular system, Beilstein Journal of Organic Chemistry 2014, 10, 2809-2820, ISSN 1860-5397, https://doi.org/10.3762/bjoc.10.298 (ISI 2.757/ ISI(2018) = 2.595/Q2) 8. Corpaş, L.; Hădărugă, N.G.; David, I.; Pîrşan, P.; Hădărugă, D.I.*; Isengard, H.-D., Karl Fischer water titration – Principal component analysis approach on wheat flour, Food Analytical Methods 2014, 7(6), 1353-1358, ISSN 1936-9751, https://doi.org/10.1007/s12161-013-9757-7 (ISI 1.956/ ISI(2018) = 2.413/Q2) 9. Menezes, P.P.; Serafini, M.R.; Quintans-Júnior, L.J.; Silva, G.F.; Oliveira, J.F.; Carvalho, F.M.S.; Souza, J.C.C.; Matos, J.R.; Alves, P.B.; Matos, I.L.; Hădărugă, D.I.; Araújo, A.A.S., Inclusion complex of (-)-linalool and β-cyclodextrin, Journal of Thermal Analysis and Calorimetry 2014, 115(3), 2429-2437, ISSN 1388-6150, https://doi.org/10.1007/s10973-013-3367-x (ISI2014 2.042/ ISI(2018) = 2.471/Q2) 10. Hegheş, A.; Hădărugă, N.G.; Fuliaş, A.-V.; Bandur, G.N.; Hădărugă, D.I.*; Dehelean. C.-A., Capsicum annuum extracts/β-cyclodextrin complexes: Thermal analyses – Karl Fischer water titration correlations and antioxidant activity, Journal of Thermal Analysis and Calorimetry 2015, 120, 603-615, ISSN 1388-6150, https://doi.org/10.1007/s10973-014-4229-x (ISI 1.781/ ISI(2018) = 2.471/Q2)

Teză de doctorat Relaţii structură-proprietăţi în clasa substanţelor odorante (Coordonator Ştiinţific Acad. Prof. Dr. Zeno SIMON), Universitatea de Vest din Timişioara (IOD), domeniul “Chimie”, 2003 (Diplomă de Doctor seria C, nr. 0005779)

Conf. Dr. Ing. Daniel-Ioan HĂDĂRUGĂ

Cărţi şi capitole de carte publicate în străinătate

1. Margolis, S.A.; Huang, P.H.; Hădărugă, N.G.; Hădărugă, D.I.*, Water determination. In: Worsfold, P.; Poole, C.; Townshend, A.; Miro, M. (Eds.), Encyclopedia of Analytical Science. Chemistry, Molecular Sciences and Chemical Engineering Reference Module, 3rd ed., Elsevier Ltd, Oxford, 2019, pp. 382-390, ISBN 978-0-12-409547-2.14505-6, https://doi.org/10.1016/B978-0-12-409547- 2.14505-6 2. Hădărugă, N.G.; Bandur, G.N.; Hădărugă, D.I.*, Thermal analyses of cyclodextrin complexes. In: Cyclodextrin Fundamentals, Reactivity and Analysis, Fourmentin, S.; Crini, G.; Lichtfouse, E. (Eds.), in series: “Environmental Chemistry for a Sustainable World”, vol. 16, Springer International Publishing AG (part of Springer Nature), Cham, 2018, ISBN (print): 978-3-319-76158-9, eISBN: 978- 3-319-76159-6, series ISSN: 2213-7114, pp. 155-221, https://doi.org/10.1007/978-3-319-76159-6_4 3. Kfoury, M.; Hădărugă, N.G.; Hădărugă, D.I.; Fourmentin, S., Cyclodextrins as encapsulation material for flavors and aroma. In: Encapsulations. Nanotechnology in Agri-Food Industry, vol. 2, Grumezescu, A.M. (ed.), Elsevier, Amsterdam, 2016, pp. 127-192, ISBN: 978-0-12-804307-3, https://doi.org/10.1016/B978-0-12-804307-3.00004-1, 4. Olah, M.; Rad, R.; Ostopovici, L.; Bora, A.; Hădărugă, N.G.; Hădărugă, D.; Moldovan, R.; Fulias, A.; Mracec, M.; Oprea, T.I., WOMBAT and WOMBAT-PK: Bioactivity databases for lead and drug discovery (Expanding the genetic code. Chemical informatics); In: Chemical Biology: From Small Molecules to Systems Biology and Drug Design, Wiley-VCH, New York, 2007, pp. 760-786, ISBN- 10: 352-731-150-5, ISBN-13: 978-352-731-150-7, doi: https://doi.org/10.1002/9783527619375.ch13b, URL: http://onlinelibrary.wiley.com/book/10.1002/9783527619375

Cărţi publicate în ţară

1. Hădărugă, D.I., Ciclodextrine şi complecşi ai ciclodextrinelor cu aplicaţii alimentare - analize specifice moderne, Editura Eurostampa, Timişoara, 2019, 257 pp., ISBN 978-606-32-0772-3. 2. Hădărugă, D.I., CICLODEXTRINE. Fundamente, aplicaţii farmaceutice şi alimentare (I), Editura Eurostampa, Timişoara, 2014, 111 pp., ISBN 978-606-569-945-8. 3. Hădărugă, D.I.; Hădărugă, N.G., Compuşi odoranţi şi aromatizanţi, Ed. Politehnica, Timişoara, 2003, 254 p, ISBN 973-625-038-5.

Brevete de invenţie

1. Poşta, D.S.; Hădărugă, N.G.; Peţ, E.; Poşta, G.M.; Peţ, I.; Camen, D.D.; Hădărugă, D.I., Procedeu de obţinere a unui produs de înrădăcinare pe bază de extract de salcie (genul Salix L.) (Manufacturing process and rooting product based on willow (genus Salix) extract), Brevet de invenţie OSIM RO131178 (A0) din 30.06.2016 (nr. cerere a 2015 00786 / 03.11.2015, cf. Hotărâre OSIM nr. 3 / 123 / 30.08.2018), Derwent Primary Accession Number: 2016-396448, https://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true &locale=en_EP&FT=D&date=20160630&CC=RO&NR=131178A0&KC=A0#

Articole in extenso, publicate în reviste cotate ISI cu factor de impact – quartila Q1 (zona roşie) 1. Hădărugă, N.G.; Szakal, R.N.; Chirilă, C.A.; Lukinich-Gruia, A.T.; Păunescu, V.; Muntean, C.; Rusu, G.; Bujancă, G.; Hădărugă, D.I., Complexation of Danube common nase (Chondrostoma nasus L.) oil by β-cyclodextrin and 2-hydroxypropyl-β-cyclodextrin, Food Chemistry 2020, 303, art. 125419, ISSN 0308-8146, https://doi.org/10.1016/j.foodchem.2019.125419 (ISI 5.399 / Q1) 2. Hădărugă, N.G.; Bandur, G.N.; David, I.; Hădărugă, D.I.*, A review on thermal analyses of cyclodextrins and cyclodextrin complexes, Environmental Chemistry Letters 2019, 17, 349-373, ISSN 1610-3653, https://doi.org/10.1007/s10311-018-0806-8 (ISI 4.617 (2018) / Q1) 3. Hădărugă, D.I.; Birău (Mitroi), C.L.; Gruia, A.T.; Păunescu, V.; Bandur, G.N.; Hădărugă, N.G., Moisture evaluation of β-cyclodextrin/fish oils complexes by thermal analyses: A data review on common barbel (Barbus barbus L.), Pontic shad (Alosa immaculata Bennett), European wels catfish (Silurus glanis L.), and common bleak (Alburnus alburnus L.) living in Danube river, Food Chemistry 2017, 236, 49-58, ISSN 0308-8146, https://doi.org/10.1016/j.foodchem.2017.03.093 (ISI 4.946/ ISI(2018) = 5.399/Q1) 4. Ünlüsayin, M.; Hădărugă, N.G.; Rusu, G.; Gruia, A.T.; Păunescu, V.; Hădărugă, D.I.*, Nano- encapsulation competitiveness of omega-3 fatty acids and correlations of thermal analysis and Karl

Conf. Dr. Ing. Daniel-Ioan HĂDĂRUGĂ

Fischer water titration for European anchovy (Engraulis encrasicolus L.) oil / β-cyclodextrin complexes, LWT – Food Science and Technology 2016, 68, 135-144, ISSN 0023-6438, https://doi.org/10.1016/j.lwt.2015.12.017, (ISI 2.329/ ISI(2018) = 3.714/Q1) 5. Hădărugă, D.I.*; Costescu, C.I.; Corpaş, L.; Hădărugă, N.G.; Isengard, H.-D., Differentiation of rye and wheat flour as well as mixtures by using the kinetics of Karl Fischer water titration, Food Chemistry 2016, 195, 49-55, ISSN 0308-8146, https://doi.org/10.1016/j.foodchem.2015.08.124 (ISI 4.529/ ISI(2018) = 5.399/Q1). 6. Hădărugă, N.G.; Hădărugă, D.I.; Isengard, H.-D., Water content of natural cyclodextrins and their essential oil complexes: a comparative study between Karl Fischer titration and thermal methods, Food Chemistry 2012, 132(4), 1741-1748, ISSN 0308-8146, https://doi.org/10.1016/j.foodchem.2011.11.003, ISSN: 0308-8146 (ISI 3.334/ ISI(2018) = 5.399/Q1). 7. Hădărugă, D.I.*; Hădărugă, N.G.; Bandur, G.; Isengard, H.-D., Water content of flavonoid/cyclodextrin nanoparticles: relationship with the structural descriptors of biologically active compounds, Food Chemistry 2012, 132(4), 1651-1659, ISSN 0308-8146, https://doi.org/10.1016/j.foodchem.2011.06.004, ISSN (print): 0308-8146 (ISI 3.334 / ISI(2018) = 5.399/Q1). 8. Hădărugă, N.G.; Hădărugă, D.I.*; Păunescu, V.; Tatu, C.; Ordodi, V.L.; Bandur, G.; Lupea, A.X., Thermal Stability of Linoleic Acid / α- and β-Cyclodextrin Complexes, Food Chemistry 2006, 99(3), 500-508, ISSN 0308-8146, https://doi.org/10.1016/j.foodchem.2005.08.012, (ISI2006 2.433 / ISI(2018) = 5.399/Q1). 9. Hădărugă, D.I.*; Mureşan, S.; Bologa, C.; Chiriac, A.; Simon, Z.; Cofar, Luciana; Naray-Szabo, G., QSAR for Cycloaliphatic Alcohols with Quantitatively Defined Sandalwood Odour Characteristics, Quant. Struct.-Act. Relat. 1999, 18(3), 253-261, ISSN: 0931-8771 (QSAR & Combinatorial Sciences, ISSN 1611-020X; Molecular Informatics, ISSN: 1868-1751); https://doi.org/10.1002/(SICI)1521- 3838(199907)18:3<253::AID-QSAR253>3.0.CO;2-S (ISI1999 1.803 / ISI(2018) = 2.771/Q1) 10. Dăescu, C.; Hădărugă, D.I., Substantivity of Azoic Coupling Components ‘Azotols’, Dyes & Pigments 1999, 40(2-3), 235-241, ISSN 0143-7208, https://doi.org/10.1016/S0143-7208(98)00062-X (ISI1999 0.667 / ISI(2018) = 4.018/Q1).

Articole in extenso, publicate în reviste cotate ISI cu factor de impact – quartila Q2 (zona galbenă) 11. Hădărugă, D.I.*; Ünlüsayin, M.; Gruia, A.T.; Birău (Mitroi), C.; Rusu, G.; Hădărugă, N.G., Thermal and oxidative stability of Atlantic salmon oil (Salmo salar L.) and complexation with β-cyclodextrin, Beilstein Journal of Organic Chemistry 2016, 12, 179-191, ISSN 1860-5397, https://doi.org/10.3762/bjoc.12.20 (ISI 2.337/ ISI(2018) = 2.595/Q2). 12. Hădărugă, D.I.*; Hădărugă, N.G.; Costescu, C.I.; David, I.; Gruia, A.T., Thermal and oxidative stability of the Ocimum basilicum L. essential oil/β-cyclodextrin supramolecular system, Beilstein Journal of Organic Chemistry 2014, 10, 2809-2820, ISSN 1860-5397, https://doi.org/10.3762/bjoc.10.298 (ISI 2.757/ ISI(2018) = 2.595/Q2) 13. Hegheş, A.; Hădărugă, N.G.; Fuliaş, A.-V.; Bandur, G.N.; Hădărugă, D.I.*; Dehelean. C.-A., Capsicum annuum extracts/β-cyclodextrin complexes: Thermal analyses – Karl Fischer water titration correlations and antioxidant activity, Journal of Thermal Analysis and Calorimetry 2015, 120, 603-615, ISSN 1388-6150, https://doi.org/10.1007/s10973-014-4229-x (ISI 1.781/ ISI(2018) = 2.471/Q2) 14. Corpaş, L.; Hădărugă, N.G.; David, I.; Pîrşan, P.; Hădărugă, D.I.*; Isengard, H.-D., Karl Fischer water titration – Principal component analysis approach on wheat flour, Food Analytical Methods 2014, 7(6), 1353-1358, ISSN 1936-9751, https://doi.org/10.1007/s12161-013-9757-7 (ISI 1.956/ ISI(2018) = 2.413/Q2) 15. Menezes, P.P.; Serafini, M.R.; Quintans-Júnior, L.J.; Silva, G.F.; Oliveira, J.F.; Carvalho, F.M.S.; Souza, J.C.C.; Matos, J.R.; Alves, P.B.; Matos, I.L.; Hădărugă, D.I.; Araújo, A.A.S., Inclusion complex of (-)-linalool and β-cyclodextrin, Journal of Thermal Analysis and Calorimetry 2014, 115(3), 2429-2437, ISSN 1388-6150, https://doi.org/10.1007/s10973-013-3367-x (ISI2014 2.042/ ISI(2018) = 2.471/Q2) 16. Riviş, A.; Hădărugă, N.G.; Gârban, Z.; Hădărugă, D.I.*, Titanocene / cyclodextrin supramolecular systems: a theoretical approach, Chemistry Central Journal 2012, 6, art. 129, ISSN 1752-153X, https://doi.org/10.1186/1752-153X-6-129, (ISI 1.312/ ISI(2018) = 2.442/Q2)

Conf. Dr. Ing. Daniel-Ioan HĂDĂRUGĂ

Articole in extenso, publicate în reviste cotate ISI cu factor de impact – quartilele Q3 şi Q4 (zona gri) 17. Şuta, L.M.; Tudor, A,; Sandulovici, C.R.; Stelea, L.; Hădărugă, D.I.; Mircioiu, C.; Balint, G.S., Multivariate Statistical Analysis Regarding the Formulation of Oxicam-Based Pharmaceutical Hydrogels, Revista de Chimie 2017, 68(4), 726-731, ISSN 0034-7752 (ISI 1.412/ ISI(2018) = 1.605/Q3) 18. Ivan, A.; Herman, H.; Baltă, C.; Hădărugă, D.I.; Mihali, C.V.; Ardelean, A.; Hermenean, A., Berberis vulgaris extract/β-cyclodextrin complex increases protection of hepatic cells via suppression of apoptosis and lipogenesis pathways, Experimental and Therapeutic Medicine 2017, 13(5), 2143- 2150, ISSN 1792-0981, https://doi.org/10.3892/etm.2017.4240 (ISI 1.410/ ISI(2018) = 1.448/Q4) 19. Şuta, L.-M.; Ledeţi, I.; Suciu, L.; Hădărugă, D.I.; Fuliaş, A.; Belu, I., Study Regarding the Behaviour of Encapsulated Piroxicam in Liquid Media, Revista de Chimie (Bucharest) 2015, 66(5), 718-721, ISSN 0034-7752 (ISI 0.956/ ISI(2018) = 1.605/Q3) 20. Şuta, L.-M.; Vlaia, L.; Fuliaş, A.; Ledeţi, I.; Hădărugă, D.I.; Mircioiu, C., Evaluation Study of the Inclusion Complexes of Some Oxicams with 2-hydroxypropyl-β-cyclodextrin, Revista de Chimie (Bucharest) 2013, 64(11), 1279-1283, ISSN 0034-7752 (ISI 0.677/ ISI(2018) = 1.605/Q3) 21. Hădărugă, N.G.; Hădărugă, D.I.*; Isengard, H.-D., “Surface water” and “strong-bonded water” in cyclodextrins: a Karl Fischer titration approach, Journal of Inclusion Phenomena and Macrocyclic Chemistry 2013, 75 (3-4), 297-302, ISSN 1388-3127, https://doi.org/10.1007/s10847-012-0143-7; ISSN (Print): 0923-0750, ISSN (Online): 1573-1111 (ISI 1.426/ ISI(2018) = 1.429 /Q3) 22. Şuta, L.-M.; Vlaia, L.; Vlaia, V.; Olariu, I.; Hădărugă, D.I.; Mircioiu, C., Study of the complexation behavior of tenoxicam with cyclodextrins, Farmacia 2012, 60(4), 475-483, ISSN 0014-8237 (ISI 0.578/ ISI(2018) = 1.527/Q4) 23. Costescu, C.; Corpaş, L.; Hădărugă, N.G.; Hădărugă, D.I.; Gârban, Z., Cyclodextrins and small unilamellar liposomes: a comparative theoretical approach, Studia Universitatis UBB, Seria Chemia 2011, 56(3), 83-88, ISSN (print) 1224-7154, ISSN (online) 2065-9520 (ISI 0.129/ ISI(2018) = 0.275/Q4) 24. Pînzaru, I.A.; Hădărugă, D.I.*; Hădărugă, N.G.; Corpaş, L.; Peter, F., Hepatoprotective flavonoid bioconjugate / β-cyclodextrin nanoparticles: DSC – molecular modeling correlation, Digest Journal of Nanomaterials and Biostructures 2011, 6(4), 1605-1617, ISSN 1842-3582 (ISI 1.200/ ISI(2018) = 0.638/Q4) 25. Pleşa, C.M.; Hădărugă, D.I.; Hădărugă, N.G.; Gharibeh Branic, A.; Ardelean, A.; Lupea, A.X., Juniperus communis and Juniperus virginiana Hydrophobic Extracts: A Multivariate Analysis Approach, Revista de Chimie 2011, 62(9), 941-946, ISSN 0034-7752 (ISI 0.599/ ISI(2018) = 1.605/Q3) 26. Gharibeh Branic, A.; Pleşa, C.M.; Hădărugă, N.G.; Ardelean, A.; Hădărugă, D.I.; Ordodi, V.L.; Gruia, A.T.; Lupea, A.X., A Comparative Study of Juniperus communis and Juniperus virginiana Extracts: The Influence of Method, Solvent, and Provenience, Revista de Chimie 2011, 62(5), 508-513, ISSN 0034-7752 (ISI 0.599/ ISI(2018) = 1.605/Q3) 27. Hădărugă, N.G.; Gharibeh Branic, A.; Hădărugă, D.I.*; Gruia, A.; Pleşa, C.; Costescu, C.; Ardelean, A.; Lupea, A.X., Comparative study on Juniperus communis and Juniperus virginiana essential oils: TLC and GC analyses, Journal of Planar Chromatography - Modern TLC 2011, 24(2), 130-135, https://doi.org/10.1556/JPC.24.2011.2.9, ISSN (print): 0933-4173, ISSN (online): 1789-0993 (ISI 0.767/ ISI(2018) = 0.826/Q4) 28. Miclea, L.-M.; Vlaia, L.; Vlaia, V.; Hădărugă, D.I.; Mircioiu, C., Preparation and Characterization of Inclusion Complexes of Meloxicam and α-Cyclodextrin and β-Cyclodextrin, Farmacia 2010, 58(5), 583-593, ISSN 0014-8237 (ISI 0.850/ ISI(2018) = 1.527/Q4) 29. Hădărugă, D.I.; Hădărugă, N.G.; Lazău, C.; Raţiu, C.; Crăciun, C.; Grozescu, I., Liposomes containing undoped and Au+/Ag+ doped titanium dioxide nanoparticles, Digest Journal of Nanomaterials and Biostructures 2010, 5(4), 919-925, ISSN 1842-3582 (ISI 2.079 ISI(2018) = 0.638/Q4) 30. Hădărugă, D.I.*; Hădărugă, N.G.; Butnaru, G.; Tatu, C.; Gruia, A., Bioactive microparticles (10): Thermal and oxidative stability of nicotine and its complex with β-cyclodextrin, Journal of Inclusion Phenomena and Macrocyclic Chemistry 2010, 68(1), 155-164, https://doi.org/10.1007/s10847-010- 9761-0; ISSN 0923-0750 (ISI 1.220 ISI(2018) = 1.429/Q3) 31. Hădărugă, D.I.*; Hădărugă, N.G.; Bandur, G.; Riviş, A., Costescu, C.; Ordodi, V.; Ardelean, A., Berberis vulgaris extract/β-cyclodextrin nanoparticles: synthesis and characterization, Revista de Chimie 2010, 61(7), 669-675, ISSN 0034-7752 (ISI 0.693 ISI(2018) = 1.605/Q3) 32. Lazău, C.; Sfîrloagă, P.; Raţiu, C.; Orha, C.; Ioitescu, A.; Miron, I.; Novaconi, S.; Hădărugă, D.I.; Hădărugă, N.G.; Bandur, G.N.; Rusu, G.; Grozescu, I., Synthesis of Bioactive Materials Based on

Conf. Dr. Ing. Daniel-Ioan HĂDĂRUGĂ

Undoped/Doped TiO2 and Their Nanocrystals with alpha- / beta-Cyclodextrins, Journal of Optoelectronics and Advanced Materials 2009, 11(7), 981-987, ISSN (print): 1454-4164, ISSN (online): 1841-7132 (ISI 0.433 ISI(2018) = 0.588/Q4) 33. Hădărugă, D.I.*; Hădărugă, N.G.; Hermenean, A.; Riviş, A., Pâslaru, V.; Codina, G., Bionanomaterials: Thermal Stability of the Oleic Acid / α- and β-cyclodextrin Complexes, Revista de Chimie 2008, 59(9), 994-998, ISSN 0034-7752 (ISI 0.389; ISI(2018) = 1.605/Q3) 34. Ienaşcu, I.; Lupea, A.X.; Hădărugă, D.I.; Hădărugă, N.G.; Popescu, I., The antimicrobial activity and quantitative structure – biological activity relationships evaluation of some novel 2- hydroxybenzamide derivatives, Revista de Chimie 2008, 59(2), 247-250, ISSN 0034-7752 (ISI 0.389; ISI(2018) = 1.605/Q3). 35. Costescu, C.I.; Hădărugă, N.G.; Hădărugă, D.I.*; Riviş, A.; Ardelean, A.; Lupea, A.X., Bionanomaterials: Synthesis, Physico-Chemical and Multivariate Analyses of the Dicotyledonatae and Pinatae Essential Oil / β-Cyclodextrin Nanoparticles, Revista de Chimie 2008, 59(7), 739-744, ISSN 0034-7752 (ISI 0.389; ISI(2018) = 1.605/Q3) 36. Riviş, A.; Hădărugă, N.G.; Hădărugă, D.I.; Traşcă, T.; Drugă, M.; Pînzaru, I.A., Bioactive nanoparticles. The complexation of odorant compounds with α- and β-cyclodextrin, Revista de Chimie 2008, 59(2), 149-153, ISSN 0034-7752 (ISI 0.389; ISI(2018) = 1.605/Q3) 37. Hădărugă, D.I.*; Hădărugă, N.G.; Riviş, A.; Gruia, A.; Pînzaru, I.A., Thermal and Oxidative Stability of the Allium sativum L. Bioactive Compounds/α- and β-Cyclodextrin Nanoparticles, Revista de Chimie 2007, 58(11), 1009-1015, ISSN 0034-7752 (ISI 0.261; ISI(2018) = 1.605/Q3). 38. Hădărugă, N.G.; Hădărugă, D.I.*; Riviş, A.; Păunescu, V.; Costescu, C.; Lupea, A.X., Bioactive Nanoparticles. Essential Oil from Lamiaceae Family Plants / β-Cyclodextrin Supramolecular Systems, Revista de Chimie 2007, 58(10), 909-914, ISSN 0034-7752 (ISI 0.261; ISI(2018) = 1.605/Q3). 39. Hădărugă, D.I.; Hădărugă, N.G.; Resiga, D.; Pode, V.; Dumbravă, D.; Lupea, A.X., Obtaining and Characterization of Sage (Salvia sclarea L.) Essential Oil/β-Cyclodextrin Supramolecular Systems, Revista de Chimie 2007, 58(6), 566-573, ISSN 0034-7752 (ISI 0.261 ISI(2018) = 1.605/Q3). 40. Hădărugă, N.G.; Hădărugă, D.I.*; Lupea, A.X.; Păunescu, V.; Tatu, C., Bioactive Nanoparticles (7). Essential Oil from Apiaceae and Pinaceae Family Plants/β-Cyclodextrin Supramolecular Systems, Revista de Chimie 2005, 56(8), 876-882, ISSN 0034-7752 (ISI2005 0.278 / ISI(2018) = 1.605/Q3). 41. Dăescu, C.; Hădărugă, D.I., Substantivity of Anthraquinone Vat Dyes, Journal of the Society of Dyers & Colourists 2000, 116(2), 48-51, ISSN 0037-9859 (Coloration Technology, ISSN 1472-3581), https://doi.org/10.1111/j.1478-4408.2000.tb00020.x (ISI2000 0.373 / ISI(2018) = 0.39/Q3)

Articole in extenso, publicate în reviste şi volumele unor manifestări ştiinţifice indexate BDI 1. Ivanovici, M.; Sicoe, G.; Hădărugă, D.I., Kinetics and antiradical activity of natural and synthetic phenolic compounds by DPPH method: a comparative study, Journal of Agroalimentary Processes and Technologies 2018, 24(2), 97-103, ISSN 2069-0053, eISSN 2068-9551, Google Academic, Evisa, https://www.journal-of- agroalimentary.ro/admin/articole/70114XL14_Hadaruga_Daniel_2018_24(2)_97-103.pdf 2. Sicoe, G.; Zippenfening, S.E.; Simandi, M.D.; Szakal, R.N.; Gălan, I.M.; Rădulescu, L.; David, I.; Hădărugă, D.I.; Mocanu, C.; Puiu, I.; Golea, G.M.; Hădărugă, N.G., Halogen drying kinetics of some vegan crackers as fortified food products, Journal of Agroalimentary Processes and Technologies 2018, 24(4), 330-337, ISSN 2069-0053, eISSN 2068-9551, Google Academic, Evisa, https://www.journal-of- agroalimentary.ro/admin/articole/96430L53_Gabriela_Sicoe_Crackers_Halogen_drying_330-337.pdf 3. Birău (Mitroi), C.L.; Hădărugă, D.I.; Hădărugă, N.G., Synthesis and thermal analysis of β- cyclodextrin / Danube common carp (Cyprinus carpio L.) oil complexes, Journal of Agroalimentary Processes and Technologies 2017, 23(3), 110-119, ISSN 2069-0053, eISSN 2068-9551, Google Academic, Evisa, http://journal-of- agroalimentary.ro/admin/articole/61096L22_Mitroi_Cristina_JAPT_2017_23(3)_110-119.pdf 4. Birău (Mitroi), C.L.; Hădărugă, D.I.; Hădărugă, N.G., β-Cyclodextrin / Danube common rudd (Scardinius erythrophthalmus L.) oil complexes – synthesis and characterization, Journal of Agroalimentary Processes and Technologies 2017, 23(2), 78-84, ISSN 2069-0053, eISSN 2068- 9551, Google Academic, Evisa, http://journal-of- agroalimentary.ro/admin/articole/3939L16_Mitroi_Cristina_2017_23(2)_78-84.pdf 5. Birău (Mitroi), C.L.; Hădărugă, D.I.; Riviş, A.; Hădărugă, N.G., Omega-3 fatty acids and their glycerides / natural cyclodextrin interactions: molecular modeling and docking studies, Journal of Agroalimentary Processes and Technologies 2016, 22(4), 226-235, ISSN 2069-0053, eISSN 2068-

Conf. Dr. Ing. Daniel-Ioan HĂDĂRUGĂ

9551, Google Academic, Evisa, http://www.journal-of- agroalimentary.ro/admin/articole/85868L2_Hadaruga_Omega-3_Fatty_acids_CDs.pdf 6. Hădărugă, D.I.; Pantea, C.; Hădărugă, N.G., Antioxidant activity and kinetics on kiwi fruit (Actinidia deliciosa) ethanolic extracts by 2,2-diphenyl-1-picrylhydrazyl (DPPH·) method, Journal of Agroalimentary Processes and Technologies 2016, 22(4), 207-211, ISSN 2069-0053, eISSN 2068- 9551, Google Academic, Evisa, https://www.journal-of- agroalimentary.ro/admin/articole/6823ML11_Hadaruga_Kiwi_AO.pdf 7. Sav, A.; Hădărugă, D.I., Silibinin-saturated fatty acid bioconjugate / natural cyclodextrin interactions: molecular modeling, docking and QSPR experiments, Journal of Agroalimentary Processes and Technologies 2017, 23(1), 5-12, ISSN 2069-0053, eISSN 2068-9551, Google Academic, Evisa, https://www.journal-of- agroalimentary.ro/admin/articole/67955L2_Hadaruga_Silibin___bioconjugates_CDs.pdf 8. Zippenfening, S.E.; Hădărugă, D.I.; Negrea, I.; Velciov, A.; Hădărugă, N.G., Karl Fischer Titration of Salami Products: Variation of the Water Content During Ripening and Kinetics of the KFT Process, Chemical Bulletin of the Polytechnic University of Timisoara, Romania, Series of Chemistry and Environmental Engineering 2015, 60(74-1), 18-24, Google Academic, http://chemicalbulletin.upt.ro/admin/articole/66114art_4(18-24).pdf 9. Costescu, C.I.; Rus, D.; Hădărugă, N.G.; Pogor, V.; Badea, M.; Mateican, E.; Szakal, R.; Olaru. P.; Hădărugă, D.I., Solvent influence on the antioxidant activity of pomegranate extracts, Journal of Agroalimentary Processes and Technologies 2015, 21(1), 21-27, ISSN 2069-0053, eISSN 2068- 9551, Google Academic, Evisa, https://www.journal-of- agroalimentary.ro/admin/articole/9168L5_Vol_21(1)_2015_21_27.pdf 10. Pană, A.-M.; Popa, M.; Furca, L.-M.; Sfîrloagă, P.; Hădărugă, D.I.; Bandur, G.N.; Crepy, L.; Rusnac, L.-M., New semi-interpenetrating networks hydrogels derived from monosaccharide based oligomers, chitosan and 2-hydroxyethyl methacrylate, Journal of Hydrogels 2015, 1(1), 26-33, ISSN 2377-6293, Google Scholar, URL: www.aspbs.com/jh, https://dx.doi.org/10.1166/jh.2015.1007 11. Costescu, C.I.; Rădoi, B.P.; Hădărugă, N.G.; Gruia, A.T.; Riviş, A.; Pârvu, D.; David, I.; Hădărugă, D.I., Obtaining and characterization of Achillea millefolium L. extracts, Journal of Agroalimentary Processes and Technologies 2014, 20(2), 142-149, ISSN 2069-0053, eISSN 2068-9551, Google Academic, Evisa, https://www.journal-of- agroalimentary.ro/admin/articole/31817L22_Vol_20(2)_2014_142_149.pdf 12. Baltă, C.; Hădărugă, N.G.; Plesa (Mitar), C.M.; Ghibu, D.; Gârban, G.; Gârban, Z.; Hădărugă, D.I., Hematological properties of cisplatin and its Ficaria verna Huds. extracts / β-cyclodextrin complexes in rats, Journal of Agroalimentary Processes and Technologies 2012, 18(4), 356-359, ISSN 2069- 0053, eISSN 2068-9551, Google Academic, Evisa, https://www.journal-of- agroalimentary.ro/admin/articole/6026L72_Balta_Vol.18_4_2012_358-361.pdf 13. Corpaş, L.; Hădărugă, N.G.; Codina, G.G.; Riviş, A.; Guran, E.; Baliţa, E.-N.; Hădărugă, D.I., Phospholipids in homemade bread, Journal of Agroalimentary Processes and Technologies 2012, 18(4), 336-340, ISSN 2069-0053, eISSN 2068-9551, Google Academic, Evisa, https://www.journal- of-agroalimentary.ro/admin/articole/19616L15_Corpas_Vol.18_4__2012_336-340.pdf 14. Botiniştean, C.; Hădărugă, N.G.; Hădărugă, D.I., Jianu, I., Fatty Acids Composition by Gas Chromatography – Mass Spectrometry (GC-MS) and most important physicalchemicals parameters of Tomato Seed Oil, Journal of Agroalimentary Processes and Technologies 2012, 18(1), 89-94, ISSN 2069-0053, eISSN 2068-9551, Google Academic, Evisa, https://www.journal-of- agroalimentary.ro/admin/articole/10789L19_Botinestean_Vol.18_1__2012_89-94.pdf 15. Hădărugă, D.I., Anti-inflammatory oxicam / cyclodextrin supramolecular systems: molecular modeling and docking experiments, Journal of Agroalimentary Processes and Technologies 2011, 17(4), 456-465, ISSN 2069-0053, eISSN 2068-9551, Google Academic, Evisa, https://www.journal- of-agroalimentary.ro/admin/articole/35986L22_Hadaruga_Oxicam-CDs_456-465.pdf 16. Şuta, L.-M.; Vlaia, L.; Vlaia, V.; Hădărugă, N.G.; Hădărugă, D.I.; Mircioiu, C., Water content of oxicam/cyclodextrin nanoparticles, Journal of Agroalimentary Processes and Technologies 2011, 17(4), 419-427, ISSN 2069-0053, eISSN 2068-9551, Google Academic, Evisa, https://www.journal- of-agroalimentary.ro/admin/articole/82773L15_Suta_Marilena_Vol._17_4_419-427.pdf 17. Hădărugă, D.I., Natural and synthetic HIV-1 non-nucleoside reverse transcriptase inhibitors: a theoretical approach, Journal of Agroalimentary Processes and Technologies 2011, 17(4), 360-370, ISSN 2069-0053, eISSN 2068-9551, Google Academic, Evisa, https://www.journal-of- agroalimentary.ro/admin/articole/63574Hadaruga_QSAR_2_final.pdf 18. Hădărugă, D.I., Efavirenz derivatives and marine natural compounds with anti-HIV activity: similarity, molecular modeling, and QSAR studies, Journal of Agroalimentary Processes and Technologies 2011, 17(3), 335-343, ISSN 2069-0053, eISSN 2068-9551, Google Academic, Evisa,

Conf. Dr. Ing. Daniel-Ioan HĂDĂRUGĂ

https://www.journal-of-agroalimentary.ro/admin/articole/28500L25_Hadaruga_Vol.17_3__2011_335- 343.pdf 19. Pînzaru, I.A.; Hădărugă, D.I.*; Hădărugă, N.G.; Peter, F., Rutin-saturated fatty acid bioconjugate/cyclodextrin supramolecular systems: molecular modeling and docking studies, Journal of Agroalimentary Processes and Technologies 2011, 17(2), 123-129, ISSN 2069-0053, eISSN 2068-9551, Google Academic, Evisa, https://www.journal-of- agroalimentary.ro/admin/articole/647L5_Hadaruga_Vol.2_2011_123-129.pdf 20. Hădărugă, N.G.; Hădărugă, D.I.; Vlăzan, P.; Barbu-Tudoran, L., New liposomes containing cobalt ferrite nanoparticles: synthesis and characterization, Journal of Agroalimentary Processes and Technologies 2011, 17(1), 1-6, ISSN 2069-0053, eISSN 2068-9551, Google Academic, Evisa, https://www.journal-of- agroalimentary.ro/admin/articole/61100L1_Hadaruga_Nicoleta_Vol.17(1)_2011_1-6.pdf 21. Pleşa, C.M.; Hădărugă, N.G.; Hădărugă, D.I.; Ordodi, V.L.; Gruia, A.T.; Gharibeh Branic, A.; Ardelean, A.; Lupea, A.X., Caryophyllene from Juniperus communis and Juniperus virginiana Romanian extracts, Journal of Agroalimentary Processes and Technologies 2011, 17(1), 54-57, ISSN 2069-0053, eISSN 2068-9551, Google Academic, Evisa, https://www.journal-of- agroalimentary.ro/admin/articole/60312L10_Plesa_Carmen_Vol.1_2011.pdf 22. Toţa, C.E.; Hădărugă, N.G.; Poşta, G.; Berar, V.; Hegheş, A.; Moldovan, C.; Hădărugă, D.I., Antioxidant activity of tomato hybrids: correlation with the fertilizer used in crop, Journal of Agroalimentary Processes and Technologies 2011, 17(1), 20-24, ISSN 2069-0053, eISSN 2068- 9551, Google Academic, Evisa, https://www.journal-of- agroalimentary.ro/admin/articole/59540L4_Tota_Vol.1_2011_21-24.pdf 23. Toţa, C.E.; Hădărugă, N.G.; Poşta, G.; Berar, V.; Hegheş, A.; Corpaş, L.; Hădărugă, D.I., Flavoring compounds from tomato hybrids grown in Banat county (Romania), Journal of Agroalimentary Processes and Technologies 2011, 17(1), 7-14, ISSN 2069-0053, eISSN 2068-9551, Google Academic, Evisa, https://www.journal-of- agroalimentary.ro/admin/articole/59219L2_Tota_Vol.1_2011_7-14.pdf 24. Dumbravă, D.G.; Hădărugă, N.G.; Hădărugă, D.I.; Moldovan, C.; Raba, D., Determination by RP- HPLC of β-carotene concentration from orange (Citrus sinensis L.) fruits peel extracts, Journal of Agroalimentary Processes and Technologies 2010, 16(2), 242-246, ISSN 2069-0053, eISSN 2068- 9551, Google Academic, Evisa, https://www.journal-of- agroalimentary.ro/admin/articole/72032L50_Dumvrava_Delia_Vol.2_01-02_2010_242-246.pdf 25. Popa, V.-M.; Hădărugă, N.G.; Hădărugă, D.I.; Gruia, A.; Raba, D.-N.; Moldovan, C.; Poiana, A.-M., Fatty acids composition of some vegetable oils obtained in the West area of Romania, Journal of Agroalimentary Processes and Technologies 2010, 16(3), 394-398, ISSN 2069-0053, eISSN 2068- 9551, Google Academic, Evisa, https://www.journal-of- agroalimentary.ro/admin/articole/92109L83_Mirela__Popa_2_Vol.2_01-02_2010_394-398.pdf 26. Ciurlea, S.A.; Dehelean, C.A.; Ionescu, D.; Berko, S.; Csanyi, E.; Hădărugă, D.I.; Ganta, S.; Amiji, M.M., A comparative study regarding melanoma activity of Betulinic acid on topical ointment vs. systemic nanoemulsion delivery systems, Journal of Agroalimentary Processes and Technologies 2010, 16(4), 420-426, ISSN 2069-0053, eISSN 2068-9551, Google Academic, Evisa, https://www.journal-of- agroalimentary.ro/admin/articole/3105L88_Cristina_Dehelean_Vol.4_2010_420-426.pdf 27. Hădărugă, D.I.; Hădărugă, N.G.; Merkh, G.; Isengard, H.-D., Water content of fatty acid/cyclodextrin nanoparticles, Journal of Agroalimentary Processes and Technologies 2010, 16(2), 230-235, ISSN 2069-0053, eISSN 2068-9551, Google Academic, Evisa, https://www.journal-of- agroalimentary.ro/admin/articole/8079L48_Hadaruga_Daniel_Vol.2_01-02_2010_230-235.pdf 28. Hădărugă, D.I.; Hădărugă, N.G.; Lazău, C.; Crăciun, C.; Grozescu, I., Liposomes containing titanium dioxide nanoparticles, Journal of Agroalimentary Processes and Technologies 2010, 16(1), 62-66, ISSN 2069-0053, eISSN 2068-9551, Google Academic, Evisa, https://www.journal-of- agroalimentary.ro/admin/articole/66288L12_Hadaruga_Vol.1_01-02_2010_61-65.pdf 29. Coneac, G.; Gafiţanu, E.; Hădărugă, N.G.; Hădărugă, D.I.; Riviş, A.; Pârvu, D., Quercetin and rutin / 2-hydroxypropyl-β-cyclodextrin nanoparticles: obtaining, characterization and antioxidant activity, Journal of Agroalimentary Processes and Technologies 2009, 15(3), 441-448, ISSN 2069-0053, eISSN 2068-9551, Google Academic, Evisa, https://www.journal-of- agroalimentary.ro/admin/articole/79256L82_Hadaruga_Daniel_441-448.pdf 30. Hădărugă, D.I.; Balş, D.; Hădărugă, N.G., Insulin-Containing Amino Acids and Oligopeptides/β- Cyclodextrin Supramolecular Systems: Molecular Modeling and Docking Experiments, Chem. Bull. “Politehnica” Univ. (Timişoara) 2009, 54(68-2), 108-113, ISSN 1224-6018, eISSN 2069-6310, Google Academic, http://chemicalbulletin.upt.ro/admin/articole/54927art_11(108-113).pdf

Conf. Dr. Ing. Daniel-Ioan HĂDĂRUGĂ

31. Hădărugă, D.I.; Hădărugă, N.G.; Miclea, L.M.; Vlaia, L.; Mircioiu, C., Bioactive compounds (hepatoprotective or anti-inflammatory xenobiotics) / cyclodextrin nanoparticles: a comparative study, Journal of Agroalimentary Processes and Technologies 2009, 15(4), 478-483, ISSN 2069-0053, eISSN 2068-9551, Google Academic, Evisa, https://www.journal-of- agroalimentary.ro/admin/articole/27255L2_HadarugaNicoleta_Vol.4_478-483.pdf 32. Hădărugă, D.I., Quantitative structure – activity relationships (QSAR) in flavonoid compound class, Journal of Agroalimentary Processes and Technologies 2009, 15(3), 403-407, ISSN 2069-0053, eISSN 2068-9551, Google Academic, Evisa, https://www.journal-of- agroalimentary.ro/admin/articole/50310L75_Hadaruga_Daniel_403-407.pdf 33. Hădărugă, D.I.; Hădărugă, N.G., Antioxidant activity of Chelidonium majus L. extracts from the Banat county, Journal of Agroalimentary Processes and Technologies 2009, 15(3), 396-402, ISSN 2069-0053, eISSN 2068-9551, Google Academic, Evisa, https://www.journal-of- agroalimentary.ro/admin/articole/82868L74_Hadaruga_Daniel_396-402.pdf 34. Hădărugă, D.I.; Hădărugă, N.G., Antioxidant Activity of Hepatoprotective Silymarin and Silybum marianum L. Extract, Chem. Bull. “Politehnica” Univ. (Timişoara) 2009, 54(2), 104-107, ISSN 1224- 6018, eISSN 2069-6310, Google Academic, http://chemicalbulletin.upt.ro/admin/articole/74560art_10(104-107).pdf 35. Hădărugă, D.I.; Hădărugă, N.G.; Riviş, A.; Pârvu, D., Molecular Modeling and Docking Studies on Compositae Biocompounds-Cyclodextrin Interactions, Journal of Agroalimentary Processes and Technologies 2009, 15(2), 273-282, ISSN 2069-0053, eISSN 2068-9551, Google Academic, Evisa, https://www.journal-of-agroalimentary.ro/admin/articole/88852L18_Hadaruga_Daniel_273-282.pdf 36. Hădărugă, N.G.; Hădărugă, D.I.; Tatu, C.; Gruia, A.; Moldovan, C.; Costescu, C.; Lupea, A.X., Multivariate Analysis (PCA) in Compositae Biocompounds Class, Journal of Agroalimentary Processes and Technologies 2009, 15(2), 201-210, ISSN 2069-0053, eISSN 2068-9551, Google Academic, Evisa, https://www.journal-of- agroalimentary.ro/admin/articole/54311L4_Hadaruga_Nicoleta_201_210.pdf 37. Dumbravă, D.G.; Lupea, A.X.; Hădărugă, N.G.; Hădărugă, D.I.; Moldovan, C.; Riviş, A.; Drugă, M., Determination by Atomic Absorption Spectrometry of Mineral Content from Maize (Zea mays) Hybrids and Their Carotenoidic Extracts, Journal of Agroalimentary Processes and Technologies 2009, 15(1), 64-71, ISSN 2069-0053, eISSN 2068-9551, Google Academic, Evisa, https://www.journal-of-agroalimentary.ro/admin/articole/31738L13_Dumbrava_Delia_64_71.pdf 38. Dumbravă, D.G.; Hădărugă, N.G.; Hădărugă, D.I.; Gruia, A.; Tatu, C.; Păunescu, V.; Lupea, A.X., Antioxidant activity of some celandine (Chelidonium majus L.) carotenoidic extracts, Journal of Agroalimentary Processes and Technologies 2008, 14(2), 433-441, ISSN 2069-0053, eISSN 2068- 9551, Google Academic, Evisa, https://www.journal-of- agroalimentary.ro/admin/articole/6936311_Dumbrava.pdf 39. Costescu, C.I.; Hădărugă, N.G.; Hădărugă, D.I.; Lupea, A.X.; Riviş, A.; Pârvu, D., Antioxidant activity evaluation of some Matricaria chamomilla L. extracts, Journal of Agroalimentary Processes and Technologies 2008, 14(2), 417-432, ISSN 2069-0053, eISSN 2068-9551, Google Academic, Evisa, https://www.journal-of-agroalimentary.ro/admin/articole/6659810_Costescu.pdf 40. Hădărugă, N.G.; Hădărugă, D.I.; Bandur, G.N.; Riviş, A.; Pârvu, D.; Lupea, A.X., Protection and controlled release of fatty acids and essential oils by nanoencapsulation in cyclodextrins (a review), Journal of Agroalimentary Processes and Technologies 2008, 14(2), 381-389, ISSN 2069-0053, eISSN 2068-9551, Google Academic, Evisa, https://www.journal-of- agroalimentary.ro/admin/articole/5900604_Hadaruga.pdf 41. Coneac, G.; Gafiţanu, E.; Hădărugă, D.I.; Hădărugă, N.G.; Pînzaru, I.A.; Bandur, G.; Urşica, L.; Păunescu, V.; Gruia, A., Flavonoid Contents of Propolis from the West Side of Romania and Correlation with the Antioxidant Activity, Chem. Bull. “Politehnica” Univ. (Timişoara) 2008, 53(1-2), 56-60, ISSN 1224-6018, eISSN 2069-6310, Google Academic, http://chemicalbulletin.upt.ro/admin/articole/14305art_13(56-60).pdf 42. Hădărugă, D.I.; Hădărugă, N.G.; Mureşan, S., Activity Evaluation of Some Sandalwood Odorants Using the MTD Method, Chem. Bull. “Politehnica” Univ. (Timişoara) 2007, 52(1-2), 56-60, ISSN 1224-6018, eISSN 2069-6310, Google Academic, http://chemicalbulletin.upt.ro/admin/articole/90930art_14(56-60).pdf 43. Hădărugă, D.I.; Hădărugă, N.G.; Mureşan, S., Quantitative Structure-Odor Relationships of Some Nitro-benzenic Musks, Chem. Bull. “Politehnica” Univ. (Timişoara) 2007, 52(1-2), 51-55, ISSN 1224- 6018, eISSN 2069-6310, Google Academic, http://chemicalbulletin.upt.ro/admin/articole/24184art_13(51-55).pdf 44. Coneac, G.; Gafiţanu, E.; Hădărugă, D.I.; Hădărugă, N.G.; Riviş, A.; Bandur, G.N.; Pînzaru, I.A.; Rusu, G.; Urşica, L.; Păunescu, V.; Gruia, A.; Sebeşan, M.; Grozescu, I.; Lazău, C.; Sfîrloagă, P.,

Conf. Dr. Ing. Daniel-Ioan HĂDĂRUGĂ

Propolis Extract/β-Cyclodextrin Nanoparticles: Synthesis, Physico-Chemical, and Multivariate Analyses, Journal of Agroalimentary Processes and Technologies 2008, 14(1), 58-70, ISSN 2069- 0053, eISSN 2068-9551, Google Academic, Evisa, https://www.journal-of- agroalimentary.ro/admin/articole/88165L16_Vol_XIV_2008_Hadaruga_Daniel2.pdf 45. Hădărugă, D.I.; Hădărugă, N.G.; Mureşan, S.; Bandur, G.; Lupea, A.X.; Păunescu, V.; Riviş, A.; Tatu, C., Fatty Acid/β-Cyclodextrin Nanoparticles: Thermal Analyses and Molecular Modeling Studies, Journal of Agroalimentary Processes and Technologies 2008, 14(1), 43-49, ISSN 2069- 0053, eISSN 2068-9551, Google Academic, Evisa, https://www.journal-of- agroalimentary.ro/admin/articole/286L14_Vol_XIV_2008_Hadaruga_Daniel1.pdf

Participări la conferinţe internaţionale – străinătate

1. Hădărugă, D.I.; Hădărugă, N.G.; Bandur, G.N., Moisture content evaluation for highly hydrophobic natural compound mixtures / cyclodextrin complexes by thermal methods, The 10th International Conference on Water in Food (EFW2018), Prague, Czech Republic, September 19-21, 2018, Book of Abstracts, Oral communication OC15, pp. 33, http://www.eurofoodwater.eu/efw2018/; http://www.eurofoodwater.eu/english/index.php; http://www.efw2018.eurofoodwater.eu/ 2. Simandi, M.D.; Zippenfening, S.E.; Lukinich-Gruia, A.T.; Rusu, G.; Hădărugă, D.I.; Hădărugă, N.G., Fatty acid profile of the lipid fractions of beans (Phaseolus vulgaris L.). Evaluation of the cyclodextrin nanoencapsulation by means of moisture behavior determined by thermal analyses, The 10th International Conference on Water in Food (EFW2018), Prague, Czech Republic, September 19-21, 2018, Book of Abstracts, Poster presentation P6, pp. 46-47, http://www.eurofoodwater.eu/efw2018/; http://www.eurofoodwater.eu/english/index.php; http://www.efw2018.eurofoodwater.eu/ 3. Hădărugă, N.G.; Mitroi, C.; Szakal, R.N.; Oprean, C.; Drăghia, L.P.; Bandur, G.N.; Hădărugă, D.I., β-Cyclodextrin / Danube asp and Prussian carp oil complexes: evaluation of moisture content and nanoencapsulation efficiency by thermogravimetry and differential scanning calorimetry, The 10th International Conference on Water in Food (EFW2018), Prague, Czech Republic, September 19-21, 2018, Book of Abstracts, Poster presentation P14, pp. 55, http://www.eurofoodwater.eu/efw2018/; http://www.eurofoodwater.eu/english/index.php; http://www.efw2018.eurofoodwater.eu/ 4. Hădărugă, D.I., Water behavior on bioactive compound / cyclodextrin complexation: case studies on alkaloids, fatty acid glycerides, flavonoids and their bioconjugates, The 9th International Conference on Water in Food (EFW2016), Leuven, Belgium, May 22-24, 2016, Book of Abstracts, Oral communication OC13, pp. 27, http://www.eurofoodwater.eu/efw2016/ 5. Birău (Mitroi), C.; Hădărugă, N.G.; Ünlüsayin, M.; Gruia, A.T.; Hădărugă, D.I., Water behavior on fish oil / cyclodextrin complexation, The 9th International Conference on Water in Food (EFW2016), Leuven, Belgium, May 22-24, 2016, Book of Abstracts, Poster presentation P11, pp. 48, http://www.eurofoodwater.eu/efw2016/ 6. Hădărugă, N.G.; Ivanova, S.A.; Zippenfening, S.A.; Costescu, C.I.; Corpaş, L.; Simandi, M.; Hădărugă, D.I., Karl Fischer water titration – Principal Component Analysis approach on food products, The 9th International Conference on Water in Food (EFW2016), Leuven, Belgium, May 22- 24, 2016, Book of Abstracts, Oral & Poster presentation P14 (won “The Best Poster” Award), pp. 51, http://www.eurofoodwater.eu/efw2016/ 7. Hădărugă, D.I., Bioconjugate – cyclodextrin interactions. Enzymatic synthesis and cyclodextrin inclusion studies of natural antioxidant-essential fatty acid bioconjugates, The 4th European Conference on Cyclodextrins (EuroCD2015), Lille, France, October 6-9, 2015, Book of Abstracts, Oral communication O12, pp. 36, http://www.eurocd2015.com. 8. Ünlüsayin, M.; Hădărugă, N.G.; Gruia, A.T.; Birău (Mitroi), C.; Hădărugă, D.I., Nanoencapsulation competitivity, thermal and oxidative stability of salmon oil – β-cyclodextrin complexes, The 4th European Conference on Cyclodextrins (EuroCD2015), Lille, France, October 6-9, 2015, Book of Abstracts, Poster presentation P39, pp. 118, http://www.eurocd2015.com. 9. Hădărugă, N.G.; Baltă, C.; Muselin, F.; Ordodi, L.V.; Gârban, Z.; Hădărugă, D.I., Hematological and biochemical changes in rats by cisplatin / resveratrol / cyclodextrin complexes, The 3rd European Conference on Cyclodextrins (EuroCD2013), Antalya, Turkey, October 2-4, 2013, Poster presentation P28, http://www.eurocd2013.com/ 10. Hădărugă, D.I.; Hădărugă, N.G.; Corpaş, L.; Isengard, H.-D., Karl Fischer water titration of cyclodextrins: parameter optimization, The 7th International Conference on Water in Food (EuroFoodWater2012), Helsinki, Finland, June 3-5, 2012, Book of Abstracts, Oral communication OC19, pp. 31, http://www.eurofoodwater.eu/english/programme.php 11. Corpaş, L.; Hădărugă, N.G.; Riviş, A.; Hădărugă, D.I.; Isengard, H.-D., Water content of wheat flour and bread products by Karl Fischer titration: a PCA multivariate approach, The 7th International

Conf. Dr. Ing. Daniel-Ioan HĂDĂRUGĂ

Conference on Water in Food (EuroFoodWater2012), Helsinki, Finland, June 3-5, 2012, Book of Abstracts, Poster presentation (The best poster – oral presentation) P20, pp. 60, http://www.eurofoodwater.eu/english/programme.php 12. Hădărugă, N.G.; Pînzaru, I.A.; Corpaş, L.; Hădărugă, D.I.; Isengard, H.-D., Karl Fischer water content of saturated and unsaturated fatty acid / α- and β-cyclodextrin supramolecular systems: correlation with structural parameters, The 7th International Conference on Water in Food (EuroFoodWater2012), Helsinki, Finland, June 3-5, 2012, Book of Abstracts, Poster presentation P21, pp. 61, http://www.eurofoodwater.eu/english/programme.php 13. Hădărugă, D.I.; Hădărugă, N.G.; Isengard, H.-D., “Surface water” and “strong-bonded water” in cyclodextrins: a Karl Fischer titration approach, The 2nd European Conference on Cyclodextrins, Asti, Italy, October 2-4, 2011, Poster presentation II-P4, http://www.cdtec.unito.it/eurocd2011/ 14. Hădărugă, D.I.; Hădărugă, N.G.; Gârban, Z., Metallocene / cyclodextrin supramolecular systems: a theoretical approach, The 2nd European Conference on Cyclodextrins, Asti, Italy, October 2-4, 2011, Poster presentation VII-P4, http://www.cdtec.unito.it/eurocd2011/ 15. Hădărugă, D.I.; Pînzaru, I.A.; Hădărugă, N.G.; Peter, F., New flavonoid derivative (silybin, rutin-fatty acid bioconjugates) / cyclodextrin supramolecular systems with potential hepatoprotective activity, The 2nd European Conference on Cyclodextrins, Asti, Italy, October 2-4, 2011, Poster presentation III-P15, http://www.cdtec.unito.it/eurocd2011/ 16. Corneanu, M.; Corneanu, G.C.; Ardelean, A.; Lazău, C.; Grozescu, I.; Hădărugă, N.G.; Hădărugă, D.I.; Barbu-Tudoran, L., The Radiobiological Effect of the TiO2-Cyclodextrin Suspension, Proceedings of the 5th International Conference on Quantum, Nano, and Micro Technologies (ICQNM 2011), August 21-27, 2011, Nice/Saint Laurent du Var, France, pp. 77-82, ISBN: 978-1- 61208-151-9, http://www.iaria.org/conferences2011/ICQNM11.html 17. Pleşa, C.M.; Hădărugă, N.G.; Ardelean, A.; Hădărugă, D.I.; Gharibeh Branic, A.; Lupea, A.X., Juniperus communis and Juniperus virginiana Tetrahydrofuran Extracts, Proceedings of the 3rd International Conference „Research People and Actual Tasks on Multidisciplinary Sciences, Bulgarian National Multidisciplinary Scientific Network of the Professional Society for Research Work, Vol. 3, June 8-10, 2011, Lozenec, Bulgaria, 218-222, ISSN: 1313-7735; http://conf.bionetsyst.com/?page=home 18. Caizer, C.; Hădărugă, N.G.; Hădărugă, D.I.; Tănăsie, G.; Vlăzan, P., The Co ferrite nanoparticles/liposomes: magnetic bionanocomposites for applications in malignant tumors therapy, The 7th International Conference on Inorganic Materials, September 12-14, 2010, Biarritz, France, P2.45, http://www.im-conference.elsevier.com/pdf/poster_programme.pdf 19. Pînzaru, I.A.; Hădărugă, D.I.; Hădărugă, N.G.; Peter, F., Effect of water content on enzymatic esterification of flavonosides and flavonoids, The 3rd EuCheMS Chemistry Congress, Nürnberg, Germany, August 29-September 2, 2010, http://va.gdch.de/programm/prog_detail.asp?strVANr=5576 (Vc.004 - Biocatalysis and Biomaterials Section), http://www.euchems-congress2010.org/scientific.htm (home address) 20. Hădărugă, D.I.; Hădărugă, N.G.; Bandur, G.; Isengard, H.-D., Water content of flavonoid/cyclodextrin nanoparticles, The 6th International Conference on Water in Food, Reims, France, 21-23 March 2010, Book of Abstracts, Invited Lecture IL4, pp. 17, http://www.eurofoodwater.eu/programme.php 21. Hădărugă, N.G.; Hădărugă, D.I.; Isengard, H.-D., Water content of natural cyclodextrins and their essential oil complexes: a comparative study between Karl Fischer titration and thermal methods, The 6th International Conference on Water in Food, Reims, France, March 21-23, 2010, Book of Abstracts, P28, pp. 67, http://www.eurofoodwater.eu/programme.php

Participări la conferinţe internaţionale – România

1. Chirilă, C.A.; Vlăduţescu, T.D.; Guran, A.; Radu, L.; Mitroi, C.L.; Cugerean, M.I.; Hădărugă, D.I.; Hădărugă, N.G.; Riviş, A., Evaluation of the similarity/dissimilarity of poultry lipid profiles by Fourier transform infrared spectroscopy, Poster presentation (P41), The 2nd International Conference on Life Sciences, May 23-24, 2019, Timişoara, Romania, Book of Abstracts, pp. 45-46 2. Chirilă, C.A.; Guran, A.; Radu, L.; Mitroi, C.L.; Hădărugă, D.I.; Hădărugă, N.G., Evaluation of the similarity/dissimilarity of poultry lipid profiles by Fourier transform infrared spectroscopy, Proceedings of the 2nd International Conference on Life Sciences, May 23-24, 2019, Timişoara, Romania, Filodiritto Publisher, Bologna, In Press. 3. Hădărugă, D.I.; Chirilă, C.A.; Simandi, M.D.; Szakal, R.N.; Muntean, C.; Bandur, G.N.; Hădărugă, N.G., Cyclodextrin – edible oil complexes: Synthesis and characterization, Invited Lecture (IL2), The

Conf. Dr. Ing. Daniel-Ioan HĂDĂRUGĂ

8th International Conference on Food Chemistry, Engineering & Technology, May 23-24, 2019, Timişoara, Romania, Book of Abstracts, pp. 57-58. 4. Szakal, R.N.; Chirilă, C.A.; Simandi, M.D.; Mitroi, C.L.; Gălan, I.M.; Lucan, C.A.; Hădărugă, D.I.; Hădărugă, N.G., Evaluation of β-cyclodextrin complexation of some autochthonous fish oils by thermal methods, Oral communication (OC2), The 8th International Conference on Food Chemistry, Engineering & Technology, May 23-24, 2019, Timişoara, Romania 5. Zippenfening, S.E.; Simandi, M.D.; Vlăduţescu, T.D.; Guran, A.; Chirilă, C.A.; Hădărugă, D.I.; Hădărugă, N.G., Evaluation of the moisture content of some non-homogeneous meat products by volumetric Karl Fischer titration, Poster presentation (P42), The 8th International Conference on Food Chemistry, Engineering & Technology, May 23-24, 2019, Timişoara, Romania 6. Hădărugă, D.I.; Hădărugă, N.G.; Isengard, H.-D., Flavonoid and flavonoid-fatty acid bioconjugate / cyclodextrin complexes: a Karl Fischer water titration approach, The 8th International Conference on Water in Food (EFW2014), Timişoara, Romania, May 25-27, 2014, Book of Abstracts, Oral communication OC16, pp. 35, http://www.efw2014.eurofoodwater.eu/ 7. Hădărugă, D.I.; Santa, N.; Chera, C.; Şuta, L.M.; Rusu, G.; Hădărugă, N.G.; Isengard, H.-D., Silybin, rutin and their fatty acid bioconjugate/cyclodextrin complexes as potential hepatoprotective agents. A Karl Fisher water titration approach, The 8th International Conference on Water in Food (EFW2014), Timişoara, Romania, May 25-27, 2014, Book of Abstracts, Poster presentation P7, pp. 48, http://www.efw2014.eurofoodwater.eu/ 8. Hădărugă, D.I.; Tămăşoiu, E.; Bogdan, A.; Bandur, G.N.; Hădărugă, N.G.; Isengard, H.-D., Influence of flavonoid glycoside naringin and hesperidin fatty acid bioconjugation on the water content of their cyclodextrin complexes, The 8th International Conference on Water in Food (EFW2014), Timişoara, Romania, May 25-27, 2014, Book of Abstracts, Poster presentation P8, pp. 49, http://www.efw2014.eurofoodwater.eu/ 9. Vasilescu, C.; Hădărugă, N.G.; Rusu, G.; Hădărugă, D.I., Water content of triterpenoid saponins and their fatty acid bioconjugate/cyclodextrin complexes, The 8th International Conference on Water in Food (EFW2014), Timişoara, Romania, May 25-27, 2014, Book of Abstracts, Poster presentation P26, pp. 73, http://www.efw2014.eurofoodwater.eu/ 10. Hădărugă, D.I.; Hădărugă, N.G.; Lazău, C.; Raţiu, C.; Crăciun, C.; Grozescu, I., New liposomes containing metal oxides: Original method for evaluation of composition, Proceedings of the 10th International Symposium on Metal Elements in Environment, Medicine, and Biology, Tome X, November 11-12, 2010, Timişoara, Publishing House „Eurobit” Timişoara, 167-176, ISSN 1583- 4204, www.meemb-timisoara.ro 11. Pleşa, C.M.; Hădărugă, N.G.; Hădărugă, D.I.; Ordodi, V.; Gruia, A.; Gharibeh Branic, A.; Lupea, A.X., Identification of Volatile Compounds from Juniperus communis and Juniperus virginiana Extracts, The International Conference on Chemistry and Chemical Engineering, May 27-29, 2010, Timişoara, P. 306, pp. 59, http://www.chim.upt.ro/Facultatea-de-Chimie-Industriala-si-Ingineria- Mediului_Conferinta-internationala-de-chimie-si-inginerie-chimica_vTS.html 12. Pleşa, C.-M.; Hădărugă, N.G.; Hădărugă, D.I.; Ardelean, A.; Gharibeh-Branic, A.; Lupea, A., Antioxidant activity of Juniperus communis L. and Juniperus virginiana L. extracts and Gin type products, Proceedings of The XIVth International Eco-Conference “Safe Food”, Novi Sad, Serbia, September 22-25, 2010, pp. 439-446, ISBN: 978-86-83177-41-7, http://www.ekopokret.org.rs/documents/PROGRAM%20EKO-KONFERENCIJE%202010.pdf

Granturi naţionale:

Director 1. “Nanocapsule Bioactive: Obţinerea, Caracterizarea şi Modelarea Sistemelor Ciclodextrine- Biomolecule”, Ministerul Educaţiei şi Cercetării, CNCSIS AT, Cod 25, Contr. Nr. 32940 / 2004- 2005, Director – Conf.dr.ing. Daniel Hădărugă 2. “Odoranţi şi Aromatizanţi – Modelare Moleculară, Analiză Multivariată, QSAR”, Ministerul Educaţiei şi Cercetării, CNCSIS AT, Cod 30, Contr. Nr. 33501 / 2002-2003, Director – Conf.dr.ing. Daniel Hădărugă

Director (partener responsabil): 1. “Nanoparticule hepatoprotectoare cu biodisponibilitate mărită (Nano-HEPAT)”, Ministerul Educaţiei şi Cercetării, Programul Naţional II, PN2 62072 / 2008-2011, Partener responsabil P2 – Conf.dr.ing. Daniel Hădărugă

Conf. Dr. Ing. Daniel-Ioan HĂDĂRUGĂ

2. “Stabilirea actiunii si a efectelor stresprotectoare si/sau imunostimulatoare ale unor noi materiale biologic active (IMUNONANOMAT)”, Ministerul Educaţiei şi Cercetării, Programul Naţional II, PN2 41070 / 2007-2010, Partener responsabil P4 – Conf.dr.ing. Daniel Hădărugă 3. “Obţinerea unor nanocompozite/nanocristale cu aplicaţii în biotehnologie, agricultură, alimentaţie, sănătate şi protecţia mediului (NUSA)”, Ministerul Educaţiei şi Cercetării, Grant CEEX, P-CD-18 / 2005-2007, Partener responsabil P1 – Conf.dr.ing. Daniel Hădărugă

Granturi internaţionale:

Membru al echipei de cercetare: 1. "Oncoimunoterapie cu celule Natural Killer purtătoare de receptori himerici de antigen - CAR- NK”, P_37_786, 2017-2019, cod MySMIS: 103662, nr. Contract POC 32/01.09.2016, Centrul de Terapii Genice și Celulare în Tratamentul Cancerului – OncoGen, Spitalul Clinic Județean de Urgență “Pius Brînzeu” – Timișoara, Daniel Hădărugă – membru al echipei.

Conf. dr. ing. Daniel Ioan Hădărugă