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Skin-Related Neglected Tropical Diseases (Skin-Ntds) a New Challenge Skin-Related Neglected Tropical Diseases (Skin-NTDs) A New Challenge Edited by Roderick J. Hay and Kingsley Asiedu Printed Edition of the Special Issue Published in Tropical Medicine and Infectious Disease www.mdpi.com/journal/tropicalmed Skin-Related Neglected Tropical Diseases (Skin-NTDs) Skin-Related Neglected Tropical Diseases (Skin-NTDs) A New Challenge Special Issue Editors Roderick J. Hay Kingsley Asiedu MDPI • Basel • Beijing • Wuhan • Barcelona • Belgrade Special Issue Editors Roderick J. Hay Kingsley Asiedu The International Foundation for Dermatology World Health Organization UK Switzerland Editorial Office MDPI St. Alban-Anlage 66 4052 Basel, Switzerland This is a reprint of articles from the Special Issue published online in the open access journal Tropical Medicine and Infectious Disease (ISSN 2414-6366) from 2018 to 2019 (available at: https://www. mdpi.com/journal/tropicalmed/special issues/Skin NTDs). For citation purposes, cite each article independently as indicated on the article page online and as indicated below: LastName, A.A.; LastName, B.B.; LastName, C.C. Article Title. Journal Name Year, Article Number, Page Range. ISBN 978-3-03921-253-8 (Pbk) ISBN 978-3-03921-254-5 (PDF) Cover image courtesy of Daniel Mason. c 2019 by the authors. Articles in this book are Open Access and distributed under the Creative Commons Attribution (CC BY) license, which allows users to download, copy and build upon published articles, as long as the author and publisher are properly credited, which ensures maximum dissemination and a wider impact of our publications. The book as a whole is distributed by MDPI under the terms and conditions of the Creative Commons license CC BY-NC-ND. Contents About the Special Issue Editors ..................................... vii Preface to ”Skin-Related Neglected Tropical Diseases (Skin-NTDs)—A New Challenge” ... ix Roderick J. Hay and Kingsley Asiedu Skin-Related Neglected Tropical Diseases (Skin NTDs)—A New Challenge Reprinted from: Trop. Med. Infect. Dis. 2019, 4, 4, doi:10.3390/tropicalmed4010004 ......... 1 Avishek Singh, William John Hannan McBride, Brenda Govan and Mark Pearson Potential Animal Reservoir of Mycobacterium ulcerans: A Systematic Review Reprinted from: Trop. Med. Infect. Dis. 2018, 3, 56, doi:10.3390/tropicalmed3020056 ........ 4 Guadalupe Estrada-Ch´avez, Roberto Estrada, Daniel Engelman, Jesus Molina and Guadalupe Ch´avez-L´opez Cushing Syndrome due to Inappropriate Corticosteroid Topical Treatment of Undiagnosed Scabies Reprinted from: Trop. Med. Infect. Dis. 2018, 3, 82, doi:10.3390/tropicalmed3030082 ........ 13 Victoria Williams and Carrie Kovarik Long-Range Diagnosis of and Support for Skin Conditions in Field Settings Reprinted from: Trop. Med. Infect. Dis. 2018, 3, 84, doi:10.3390/tropicalmed3030084 ........ 20 Abebayehu Tora, Asrat Mengiste, Gail Davey and Maya Semrau Community Involvement in the Care of Persons Affected by Podoconiosis—A Lesson for Other Skin NTDs Reprinted from: Trop. Med. Infect. Dis. 2018, 3, 87, doi:10.3390/tropicalmed3030087 ........ 36 Ousmane Faye, Cheick Oumar Bagayoko, Adama Dicko, Lamissa Ciss´e, Siritio Berth´e, Bekaye Traor´e, Youssouf Fofana, Mahamoudan Niang, Seydou Tidiane Traor´e, Yamoussa Karabinta and et al. A Teledermatology Pilot Programme for the Management of Skin Diseases in Primary Health Care Centres: Experiences from a Resource-Limited Country (Mali, West Africa) Reprinted from: Trop. Med. Infect. Dis. 2018, 3, 88, doi:10.3390/tropicalmed3030088 ........ 44 Michael Marks Advances in the Treatment of Yaws Reprinted from: Trop. Med. Infect. Dis. 2018, 3, 92, doi:10.3390/tropicalmed3030092 ........ 58 Michele E. Murdoch Onchodermatitis: Where Are We Now? Reprinted from: Trop. Med. Infect. Dis. 2018, 3, 94, doi:10.3390/tropicalmed3030094 ........ 65 Ahmed Hassan Fahal, Suliman Hussein Suliman and Roderick Hay Mycetoma: The Spectrum of Clinical Presentation Reprinted from: Trop. Med. Infect. Dis. 2018, 3, 97, doi:10.3390/tropicalmed3030097 ........ 87 Daniel Engelman and Andrew C. Steer Control Strategies for Scabies Reprinted from: Trop. Med. Infect. Dis. 2018, 3, 98, doi:10.3390/tropicalmed3030098 ........ 98 v David John Chandler and Lucinda Claire Fuller The Skin—A Common Pathway for Integrating Diagnosis and Management of NTDs Reprinted from: Trop. Med. Infect. Dis. 2018, 3, 101, doi:10.3390/tropicalmed3030101 .......109 Liesbeth F. Mieras, Anna T. Taal, Erik B. Post, Alcino G. Z. Ndeve and Colette L. M. van Hees The Development of a Mobile Application to Support Peripheral Health Workers to Diagnose and Treat People with Skin Diseases in Resource-Poor Settings Reprinted from: Trop. Med. Infect. Dis. 2018, 3, 102, doi:10.3390/tropicalmed3030102 .......120 Sushma Tatipally, Aparna Srikantam and Sanjay Kasetty Polymerase Chain Reaction (PCR) as a Potential Point of Care Laboratory Test for Leprosy Diagnosis—A Systematic Review Reprinted from: Trop. Med. Infect. Dis. 2018, 3, 107, doi:10.3390/tropicalmed3040107 .......127 Wendemagegn Enbiale and Ashenafi Ayalew Investigation of a Scabies Outbreak in Drought-Affected Areas in Ethiopia Reprinted from: Trop. Med. Infect. Dis. 2018, 3, 114, doi:10.3390/tropicalmed3040114 .......141 Hollman Miller, Julian Trujillo-Trujillo and Hermann Feldmeier In Situ Diagnosis of Scabies Using a Handheld Digital Microscope in Resource-Poor Settings—A Proof-of-Principle Study in the Amazon Lowland of Colombia Reprinted from: Trop. Med. Infect. Dis. 2018, 3, 116, doi:10.3390/tropicalmed3040116 .......150 Rie R. Yotsu Integrated Management of Skin NTDs—Lessons Learned from Existing Practice and Field Research Reprinted from: Trop. Med. Infect. Dis. 2018, 3, 120, doi:10.3390/tropicalmed3040120 .......166 Gaetano Scanni The Mite-Gallery Unit: A New Concept for Describing Scabies through Entodermoscopy Reprinted from: Trop. Med. Infect. Dis. 2019, 4, 48, doi:10.3390/tropicalmed4010048 ........185 Roberto Estrada-Castan´ ˜ on, Guadalupe Estrada-Ch´avez and Mar´ıa de Guadalupe Ch´avez-L´opez Diagnosis and Management of Fungal Neglected Tropical Diseases In Community Settings—Mycetoma and Sporotrichosis Reprinted from: Trop. Med. Infect. Dis. 2019, 4, 81, doi:10.3390/tropicalmed4020081 ........197 vi About the Special Issue Editors Roderick J. Hay is Emeritus Professor of Cutaneous Infection, Kings College London, and of Dermatology, Queens University Belfast, and is currently Consultant Dermatologist at the London Bridge Hospital. He is a graduate of Oxford University and Guy’s Hospital, where he did his early training before working at the Centers for Disease Control, Atlanta, and the London School of Hygiene and Tropical Medicine. His clinical and research interests are in infectious and tropical diseases of the skin, with a focus on fungal infections. For over 30 years, Hay ran a skin infection clinic in London. He is a former Dean of the St Johns Institute of Dermatology, London. From 2002 to 2007, he was Head of the School of Medicine and Dentistry and Dean of the Faculty of Medicine and Health Sciences, Queens University Belfast. Kingsley Asiedu, Dr., received his medical degree from the Kwame Nkrumah University of Science and Technology Kumasi, Ghana, in 1990. After completing his rotations in pediatrics, obstetrics, and genecology and surgery at the Komfo Anokye Teaching Hospital in Kumasi, he then started his career in public health in 1993 in the remote rural district of Amansie West, one of the country’s most deprived areas. As the district medical officer as well as the medical officer in charge of the district hospital, St Martin’s Catholic Hospital, he managed public health activities and curative services for a population of over 100,000 people. In 1997, he earned his Masters in Public Health with a focus on health policy and management at the Rollins School of Public Health, Emory University, Atlanta, United States of America. He joined WHO in 1998 as a Medical Officer responsible for Buruli ulcer. In 2007, he took up the additional responsibility of the eradication of yaws. Since 2015, he has been coordinating the cross-disciplinary departmental work on integrating the control and management of a number of NTDs with skin presentations. His main interest is in the control of tropical diseases, district health systems, the role of community health workers in service delivery, and operational research. vii Preface to ”Skin-Related Neglected Tropical Diseases (Skin-NTDs)—A New Challenge” The skin of the patient is the first and most visible structure of the body that any healthcare worker encounters in the course of an examination. It is also highly visible, and any disease that affects it is both noticeable and will have an impact on a patient’s personal and social wellbeing. It is therefore an important entry point for diagnosis, disease mapping, and integrated management. Many of the major neglected tropical diseases produce changes in the skin, often the first indicator of illness that patients will notice. Changes to the skin often re-enforce feelings of isolation and stigma experienced by patients with NTDs, but they also provide opportunities for simplifying diagnosis and developing an integrated and strategic approach to care. A key challenge in taking the common feature of skin involvement in NTDs to a higher level is that skin disease, in general, is very common, particularly in resource-poor settings, and seeking solutions to the first without addressing the commonality of skin disease is not an option. Roderick J. Hay, Kingsley Asiedu Special Issue Editors ix Tropical
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