Early History of Infectious Disease
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Gas Gangrene Infection of the Eyes and Orbits
Br J Ophthalmol: first published as 10.1136/bjo.69.2.143 on 1 February 1985. Downloaded from British Journal of Ophthalmology, 1985, 69, 143-148 Gas gangrene infection of the eyes and orbits GERARD W CROCK,' WILSON J HERIOT,' PATTABIRAMAN JANAKIRAMAN,' AND JOHN M WEINER2 From the 'Department of Ophthalmology, University ofMelbourne, and the2C H Greer Pathology Laboratory, the Royal Victorian Eye and Ear Hospital, East Melbourne, Australia SUMMARY The literature on Clostridium perfringens infections is reviewed up to 1983. An additional case is reported with bilateral clostridial infections of the eye and orbit. One eye followed the classical course of relentless panophthalmitis, amaurosis, and orbital cellulitis ending in enucleation. The second eye contained intracameral mud and gas bubbles that were removed by vitrectomy instrumentation. Subsequent removal of the toxic cataract resulted in a final aided visual acuity of 6/18, N8. This is the third report of a retained globe, and we believe the only known case where the patient was left with useful vision. Clostridium perfringens is a ubiquitous Gram- arms, chest, and abdomen. He was admitted to a positive bacillus found in soil and bowel flora. It is the general hospital, where he was examined under most common of four clostridia species identified in anaesthesia, and his injuries were attended to. copyright. cases of gas gangrene in man.' All species are obligate Ocular findings. The right cornea and anterior anaerobes and are usually saprophytic rather than chamber were intact. There was a scleral laceration pathogenic. Clostridium perfringens is a feared con- over the superonasal area of the pars plana with taminant of limb injuries and may result in death due vitreous prolapse. -
MALARIA Despite All Differences in Biological Detail and Clinical Manifestations, Every Parasite's Existence Is Based on the Same Simple Basic Rule
MALARIA Despite all differences in biological detail and clinical manifestations, every parasite's existence is based on the same simple basic rule: A PARASITE CAN BE CONSIDERED TO BE THE DEVICE OF A NUCLEIC ACID WHICH ALLOWS IT TO EXPLOIT THE GENE PRODUCTS OF OTHER NUCLEIC ACIDS - THE HOST ORGANISMS John Maynard Smith Today: The history of malaria The biology of malaria Host-parasite interaction Prevention and therapy About 4700 years ago, the Chinese emperor Huang-Ti ordered the compilation of a medical textbook that contained all diseases known at the time. In this book, malaria is described in great detail - the earliest written report of this disease. Collection of the University of Hongkong ts 03/07 Hawass et al., Journal of the American Medical Association 303, 2010, 638 ts 02/10 Today, malaria is considered a typical „tropical“ disease. As little as 200 years ago, this was quite different. And today it is again difficult to predict if global warming might cause a renewed expansion of malaria into the Northern hemisphere www.ch.ic.ac.uk ts 03/08 Was it prayers or was it malaria ? A pious myth relates that in the year 452, the the ardent prayers of pope Leo I prevented the conquest of Rome by the huns of king Attila. A more biological consideration might suggest that the experienced warrior king Attila was much more impressed by the information that Rome was in the grip of a devastating epidemic of which we can assume today that it was malaria. ts 03/07 In Europe, malaria was a much feared disease throughout most of European history. -
Pre-Antibiotic Therapy of Syphilis Charles T
University of Kentucky UKnowledge Microbiology, Immunology, and Molecular Microbiology, Immunology, and Molecular Genetics Faculty Publications Genetics 2016 Pre-Antibiotic Therapy of Syphilis Charles T. Ambrose University of Kentucky, [email protected] Right click to open a feedback form in a new tab to let us know how this document benefits oy u. Follow this and additional works at: https://uknowledge.uky.edu/microbio_facpub Part of the Medical Immunology Commons Repository Citation Ambrose, Charles T., "Pre-Antibiotic Therapy of Syphilis" (2016). Microbiology, Immunology, and Molecular Genetics Faculty Publications. 83. https://uknowledge.uky.edu/microbio_facpub/83 This Article is brought to you for free and open access by the Microbiology, Immunology, and Molecular Genetics at UKnowledge. It has been accepted for inclusion in Microbiology, Immunology, and Molecular Genetics Faculty Publications by an authorized administrator of UKnowledge. For more information, please contact [email protected]. Pre-Antibiotic Therapy of Syphilis Notes/Citation Information Published in NESSA Journal of Infectious Diseases and Immunology, v. 1, issue 1, p. 1-20. © 2016 C.T. Ambrose This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. This article is available at UKnowledge: https://uknowledge.uky.edu/microbio_facpub/83 Journal of Infectious Diseases and Immunology Volume 1| Issue 1 Review Article Open Access PRE-ANTIBIOTICTHERAPY OF SYPHILIS C.T. Ambrose, M.D1* 1Department of Microbiology, College of Medicine, University of Kentucky *Corresponding author: C.T. Ambrose, M.D, College of Medicine, University of Kentucky Department of Microbiology, E-mail: [email protected] Citation: C.T. -
Fournier's Gangrene Caused by Listeria Monocytogenes As
CASE REPORT Fournier’s gangrene caused by Listeria monocytogenes as the primary organism Sayaka Asahata MD1, Yuji Hirai MD PhD1, Yusuke Ainoda MD PhD1, Takahiro Fujita MD1, Yumiko Okada DVM PhD2, Ken Kikuchi MD PhD1 S Asahata, Y Hirai, Y Ainoda, T Fujita, Y Okada, K Kikuchi. Une gangrène de Fournier causée par le Listeria Fournier’s gangrene caused by Listeria monocytogenes as the monocytogenes comme organisme primaire primary organism. Can J Infect Dis Med Microbiol 2015;26(1):44-46. Un homme de 70 ans ayant des antécédents de cancer de la langue s’est présenté avec une gangrène de Fournier causée par un Listeria A 70-year-old man with a history of tongue cancer presented with monocytogenes de sérotype 4b. Le débridement chirurgical a révélé un Fournier’s gangrene caused by Listeria monocytogenes serotype 4b. adénocarcinome rectal non diagnostiqué. Le patient n’avait pas Surgical debridement revealed undiagnosed rectal adenocarcinoma. d’antécédents alimentaires ou de voyage apparents, mais a déclaré The patient did not have an apparent dietary or travel history but consommer des sashimis (poisson cru) tous les jours. reported daily consumption of sashimi (raw fish). L’âge avancé et l’immunodéficience causée par l’adénocarcinome rec- Old age and immunodeficiency due to rectal adenocarcinoma may tal ont peut-être favorisé l’invasion directe du L monocytogenes par la have supported the direct invasion of L monocytogenes from the tumeur. Il s’agit du premier cas déclaré de gangrène de Fournier tumour. The present article describes the first reported case of attribuable au L monocytogenes. Les auteurs proposent d’inclure la con- Fournier’s gangrene caused by L monocytogenes. -
Q Fever in Small Ruminants and Its Public Health Importance
Journal of Dairy & Veterinary Sciences ISSN: 2573-2196 Review Article Dairy and Vet Sci J Volume 9 Issue 1 - January 2019 Copyright © All rights are reserved by Tolera Tagesu Tucho DOI: 10.19080/JDVS.2019.09.555752 Q Fever in Small Ruminants and its Public Health Importance Tolera Tagesu* School of Veterinary Medicine, Jimma University, Ethiopia Submission: December 01, 2018; Published: January 11, 2019 *Corresponding author: Tolera Tagesu Tucho, School of Veterinary Medicine, Jimma University, Jimma Oromia, Ethiopia Abstract Query fever is caused by Coxiella burnetii, it’s a worldwide zoonotic infectious disease where domestic small ruminants are the main reservoirs for human infections. Coxiella burnetii, is a Gram-negative obligate intracellular bacterium, adapted to thrive within the phagolysosome of the phagocyte. Humans become infected primarily by inhaling aerosols that are contaminated with C. burnetii. Ingestion (particularly drinking raw milk) and person-to-person transmission are minor routes. Animals shed the bacterium in urine and feces, and in very high concentrations in birth by-products. The bacterium persists in the environment in a resistant spore-like form which may become airborne and transported long distances by the wind. It is considered primarily as occupational disease of workers in close contact with farm animals or processing their be commenced immediately whenever Q fever is suspected. To prevent both the introduction and spread of Q fever infection, preventive measures shouldproducts, be however,implemented it may including occur also immunization in persons without with currently direct contact. available Doxycycline vaccines drugof domestic is the first small line ruminant of treatment animals for Q and fever. -
People, Plagues, and Prices in the Roman World: the Evidence from Egypt
People, Plagues, and Prices in the Roman World: The Evidence from Egypt KYLE HARPER The papyri of Roman Egypt provide some of the most important quantifiable data from a first-millennium economy. This paper builds a new dataset of wheat prices, land prices, rents, and wages over the entire period of Roman control in Egypt. Movements in both nominal and real prices over these centuries suggest periods of intensive and extensive economic growth as well as contraction. Across a timeframe that covers several severe mortality shocks, demographic changes appear to be an important, but by no means the only, force behind changes in factor prices. his article creates and analyzes a time series of wheat and factor Tprices for Egypt from AD 1 to the Muslim conquest, ~AD 641. From the time the territory was annexed by Octavian in 30 BCE until it was permanently taken around AD 641, Egypt was an important part of the Roman Empire. Famously, it supplied grain for the populations of Rome and later Constantinople, but more broadly it was integrated into the culture, society, and economy of the Roman Mediterranean. While every province of the sprawling Roman Empire was distinctive, recent work stresses that Egypt was not peculiar (Bagnall 1993; Rathbone 2007). Neither its Pharaonic legacy, nor the geography of the Nile valley, make it unrepresentative of the Roman world. In one crucial sense, however, Roman Egypt is truly unique: the rich- ness of its surviving documentation. Because of the valley’s arid climate, tens of thousands of papyri, covering the entire spectrum of public and private documents, survive from the Roman period (Bagnall 2009). -
Naeglaria and Brain Infections
Can bacteria shrink tumors? Cancer Therapy: The Microbial Approach n this age of advanced injected live Streptococcus medical science and into cancer patients but after I technology, we still the recipients unfortunately continue to hunt for died from subsequent innovative cancer therapies infections, Coley decided to that prove effective and safe. use heat killed bacteria. He Treatments that successfully made a mixture of two heat- eradicate tumors while at the killed bacterial species, By Alan Barajas same time cause as little Streptococcus pyogenes and damage as possible to normal Serratia marcescens. This Alani Barajas is a Research and tissue are the ultimate goal, concoction was termed Development Technician at Hardy but are also not easy to find. “Coley’s toxins.” Bacteria Diagnostics. She earned her bachelor's degree in Microbiology at were either injected into Cal Poly, San Luis Obispo. The use of microorganisms in tumors or into the cancer therapy is not a new bloodstream. During her studies at Cal Poly, much idea but it is currently a of her time was spent as part of the undergraduate research team for the buzzing topic in cancer Cal Poly Dairy Products Technology therapy research. Center studying spore-forming bacteria in dairy products. In the late 1800s, German Currently she is working on new physicians W. Busch and F. chromogenic media formulations for Fehleisen both individually Hardy Diagnostics, both in the observed that certain cancers prepared and powdered forms. began to regress when patients acquired accidental erysipelas (cellulitis) caused by Streptococcus pyogenes. William Coley was the first to use New York surgeon William bacterial injections to treat cancer www.HardyDiagnostics.com patients. -
Kellie ID Emergencies.Pptx
4/24/11 ID Alert! recognizing rapidly fatal infections Susan M. Kellie, MD, MPH Professor of Medicine Division of Infectious Diseases, UNMSOM Hospital Epidemiologist UNMHSC and NMVAHCS Fever and…. Rash and altered mental status Rash Muscle pain Lymphadenopathy Hypotension Shortness of breath Recent travel Abdominal pain and diarrhea Case 1. The cross-country trucker A 30 year-old trucker driving from Oklahoma to California is hospitalized in Deming with fever and headache He is treated with broad-spectrum antibiotics, but deteriorates with obtundation, low platelet count, and a centrifugal petechial rash and is transferred to UNMH 1 4/24/11 What is your diagnosis? What is the differential diagnosis of fever and headache with petechial rash? (in the US) Tickborne rickettsioses ◦ RMSF Bacteria ◦ Neisseria meningitidis Key diagnosis in this case: “doxycycline deficiency” Key vector-borne rickettsioses treated with doxycycline: RMSF-case-fatality 5-10% ◦ Fever, nausea, vomiting, myalgia, anorexia and headache ◦ Maculopapular rash progresses to petechial after 2-4 days of fever ◦ Occasionally without rash Human granulocytotropic anaplasmosis (HGA): case-fatality<1% Human monocytotropic ehrlichiosis (HME): case fatality 2-3% 2 4/24/11 Lab clues in rickettsioses The total white blood cell (WBC) count is typicallynormal in patients with RMSF, but increased numbers of immature bands are generally observed. Thrombocytopenia, mild elevations in hepatic transaminases, and hyponatremia might be observed with RMSF whereas leukopenia -
OSU Infectious Diseases Response Protocol
DocuSign Envelope ID: D09C67E0-CB87-454C-8430-DBD2BA83D21A Student Health Services 108 SW Memorial Place, Plageman Bldg Corvallis, OR 97331 P 541-737-9355 | F 541-737-9665 Studenthealth.oregonstate.edu OSU Infectious Diseases Response Protocol Oregon State University Student Health Services 108 SW Memorial Place Plageman Building Corvallis, OR 97331-5801 Revised July 2019 Oregon State University Infectious Diseases Response Team Student Health Services (SHS) Office of Student Life Department of Public Safety (DPS) Emergency Management Facilities Services ABM (Custodial Contract Services) Division of International Programs INTO OSU Risk Management Environmental Health and Safety (EHS) Center for Fraternity and Sorority Life (CFSL) University Relations and Marketing (URM) University Housing and Dining Services (UHDS) Counseling and Psychological Services (CAPS) Summer Session Enrollment Management-Office of Admissions Department of Recreational Sports Academic Advising Athletics Department Benton County Health Services (BCHS) Good Samaritan Regional Medical Center (GSRMC) Corvallis Fire Department (Emergency Medical Services) DocuSign Envelope ID: D09C67E0-CB87-454C-8430-DBD2BA83D21A Page 2 of 47 Promulgation, Approval, and Implementation The following is the Infectious Disease Response Protocol (IDRP) for Oregon State University (OSU). It identifies strategies and responsibilities for the prevention of and implementation of an emergency response to communicable diseases in the OSU community. This plan applies to all visitors, staff, students, volunteers or others working in OSU buildings. This plan has been approved and adopted by the OSU Infectious Disease Response Team (IDRT) and Benton County Health Services. It will be revised and updated as required. This plan supersedes any previous plan. It is understood that emergency plans exist for co-located agencies/building occupants (federal, state); where their plans are absent in instructions, this plan will be in effect. -
Bibliographic Review on the Historical Memory of Previous
REVISIONES Bibliographic review on the historical memory of previous pandemics in nursing reviews on COVID-19: a secularly documented reality Revisión bibliográfica sobre la memoria histórica de pandemias anteriores en revisiones de enfermería sobre COVID-19: una realidad secularmente documentada Joaquín León Molina1 M. Fuensanta Hellín Gil1 Eva Abad Corpa2 1 Nurse Hospital Clínico Universitario Virgen de la Arrixaca de Murcia; Advanced Nursing Care Group of the Murcian Institute of Biosanitary Research Arrixaca. Murcia. Spain. 2 Associate nurse, Hospital General Universitario Reina Sofía de Murcia; Contracted Professor PhD linked University of Murcia. Advanced Nursing Care Group of the Murcian Institute of Biosanitary Research Arrixaca. Murcia. Spain. https://doi.org/10.6018/eglobal.456511 Received: 17/11/2020 Accepted: 10/01/2021 ABSTRACT: Introduction: Reviews for COVID-19 should reflect historical antecedents from previous pandemics. Objective: We plan to map the content of recent reviews in the nursing area on COVID-19 to see if it refers to health crises due to epidemics and infectious diseases. Methodology: Descriptive narrative review. The Science Web, PubMed and Lilacs were consulted to identify the reviews; The content of the documents was consulted to detect the presence of descriptors and terms related to pandemics prior to the 21st century of humanity, taking into account the inclusion criteria and objectives of the study. Results: Relevant reviews were found only in 11 documents of the 192 identified. Conclusions: There may be reluctance to use documentation published more than a century ago; However, it would be advisable not to lose the historical memory of pandemic crises that humanity has suffered for millennia Key words: Pandemics; Epidemics; History; Ancient History. -
Diagnostic Code Descriptions (ICD9)
INFECTIONS AND PARASITIC DISEASES INTESTINAL AND INFECTIOUS DISEASES (001 – 009.3) 001 CHOLERA 001.0 DUE TO VIBRIO CHOLERAE 001.1 DUE TO VIBRIO CHOLERAE EL TOR 001.9 UNSPECIFIED 002 TYPHOID AND PARATYPHOID FEVERS 002.0 TYPHOID FEVER 002.1 PARATYPHOID FEVER 'A' 002.2 PARATYPHOID FEVER 'B' 002.3 PARATYPHOID FEVER 'C' 002.9 PARATYPHOID FEVER, UNSPECIFIED 003 OTHER SALMONELLA INFECTIONS 003.0 SALMONELLA GASTROENTERITIS 003.1 SALMONELLA SEPTICAEMIA 003.2 LOCALIZED SALMONELLA INFECTIONS 003.8 OTHER 003.9 UNSPECIFIED 004 SHIGELLOSIS 004.0 SHIGELLA DYSENTERIAE 004.1 SHIGELLA FLEXNERI 004.2 SHIGELLA BOYDII 004.3 SHIGELLA SONNEI 004.8 OTHER 004.9 UNSPECIFIED 005 OTHER FOOD POISONING (BACTERIAL) 005.0 STAPHYLOCOCCAL FOOD POISONING 005.1 BOTULISM 005.2 FOOD POISONING DUE TO CLOSTRIDIUM PERFRINGENS (CL.WELCHII) 005.3 FOOD POISONING DUE TO OTHER CLOSTRIDIA 005.4 FOOD POISONING DUE TO VIBRIO PARAHAEMOLYTICUS 005.8 OTHER BACTERIAL FOOD POISONING 005.9 FOOD POISONING, UNSPECIFIED 006 AMOEBIASIS 006.0 ACUTE AMOEBIC DYSENTERY WITHOUT MENTION OF ABSCESS 006.1 CHRONIC INTESTINAL AMOEBIASIS WITHOUT MENTION OF ABSCESS 006.2 AMOEBIC NONDYSENTERIC COLITIS 006.3 AMOEBIC LIVER ABSCESS 006.4 AMOEBIC LUNG ABSCESS 006.5 AMOEBIC BRAIN ABSCESS 006.6 AMOEBIC SKIN ULCERATION 006.8 AMOEBIC INFECTION OF OTHER SITES 006.9 AMOEBIASIS, UNSPECIFIED 007 OTHER PROTOZOAL INTESTINAL DISEASES 007.0 BALANTIDIASIS 007.1 GIARDIASIS 007.2 COCCIDIOSIS 007.3 INTESTINAL TRICHOMONIASIS 007.8 OTHER PROTOZOAL INTESTINAL DISEASES 007.9 UNSPECIFIED 008 INTESTINAL INFECTIONS DUE TO OTHER ORGANISMS -
The Politics of the Coronavirus and Its Impact on International Relations
Vol. 14(3), pp. 116-125, July-September 2020 DOI: 10.5897/AJPSIR2020.1271 Article Number: FA1630564661 ISSN: 1996-0832 Copyright ©2020 African Journal of Political Science and Author(s) retain the copyright of this article http://www.academicjournals.org/AJPSIR International Relations Full Length Research Paper The politics of the coronavirus and its impact on international relations Bheki Richard Mngomezulu Department of Political Science, Faculty of Economic and Management Sciences, University of the Western Cape, South Africa. Received 7 June, 2020; Accepted 1 July, 2020 Pandemic outbreaks are not a new phenomenon globally. There is plethora of evidence to substantiate this view. However, each epidemic has its own defining features, magnitude, and discernible impact. Societies are affected differently. The coronavirus or COVID-19 is not an incongruity. Although it is still active, thus making detailed empirical data inconclusive, it has already impacted societies in many ways - leaving indelible marks. Regarding methodology, this paper is an analytic and exploratory desktop study which draws evidence from different countries to advance certain arguments. It is mainly grounded in political science (specifically international relations) and history academic disciplines. Firstly, the paper begins by looking at how the coronavirus has affected international relations – both positively and negatively. Secondly, using examples from different countries, it argues that the virus has exposed the political leadership by bringing to bear endemic socio-economic inequalities which result in citizens responding differently to government regulations meant to flatten the curve of infection. Thirdly, in the context of Africa, the paper makes a compelling argument that some of the socio-economic situations found within the continent are remnants of colonialism and apartheid.