Pipeline and Hazardous Materials Safety Admin., DOT § 172.102
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Lifetime Organophosphorous Insecticide Use Among Private Pesticide Applicators in the Agricultural Health Study
Journal of Exposure Science and Environmental Epidemiology (2012) 22, 584 -- 592 & 2012 Nature America, Inc. All rights reserved 1559-0631/12 www.nature.com/jes ORIGINAL ARTICLE Lifetime organophosphorous insecticide use among private pesticide applicators in the Agricultural Health Study Jane A. Hoppin1, Stuart Long2, David M. Umbach3, Jay H. Lubin4, Sarah E. Starks5, Fred Gerr5, Kent Thomas6, Cynthia J. Hines7, Scott Weichenthal8, Freya Kamel1, Stella Koutros9, Michael Alavanja9, Laura E. Beane Freeman9 and Dale P. Sandler1 Organophosphorous insecticides (OPs) are the most commonly used insecticides in US agriculture, but little information is available regarding specific OP use by individual farmers. We describe OP use for licensed private pesticide applicators from Iowa and North Carolina in the Agricultural Health Study (AHS) using lifetime pesticide use data from 701 randomly selected male participants collected at three time periods. Of 27 OPs studied, 20 were used by 41%. Overall, 95% had ever applied at least one OP. The median number of different OPs used was 4 (maximum ¼ 13). Malathion was the most commonly used OP (74%) followed by chlorpyrifos (54%). OP use declined over time. At the first interview (1993--1997), 68% of participants had applied OPs in the past year; by the last interview (2005--2007), only 42% had. Similarly, median annual application days of OPs declined from 13.5 to 6 days. Although OP use was common, the specific OPs used varied by state, time period, and individual. Much of the variability in OP use was associated with the choice of OP, rather than the frequency or duration of application. -
Prohibited and Restricted Chemical List
School Emergency Response Plan and Management Guide Prohibited and Restricted Chemical List PROHIBITED AND RESTRICTED CHEMICAL LIST Introduction After incidents of laboratory chemical contamination at several schools, DCPS, The American Association for the Advancement of Science (AAAS) and DC Fire and Emergency Management Services developed an aggressive program for chemical control to eliminate student and staff exposure to potential hazardous chemicals. Based upon this program, all principals are required to conduct a complete yearly inventory of all chemicals located at each school building to identify for the removal and disposal of any prohibited/banned chemicals. Prohibited chemicals are those that pose an inherent, immediate, and potentially life- threatening risk, injury, or impairment due to toxicity or other chemical properties to students, staff, or other occupants of the school. These chemicals are prohibited from use and/or storage at the school, and the school is prohibited from purchasing or accepting donations of such chemicals. Restricted chemicals are chemicals that are restricted by use and/or quantities. If restricted chemicals are present at the school, each storage location must be addressed in the school's written emergency plan. Also, plan maps must clearly denote the storage locations of these chemicals. Restricted chemicals—demonstration use only are a subclass in the Restricted chemicals list that are limited to instructor demonstration. Students may not participate in handling or preparation of restricted chemicals as part of a demonstration. If Restricted chemicals—demonstration use only are present at the school, each storage location must be addressed in the school's written emergency plan. Section 7: Appendices – October 2009 37 School Emergency Response Plan and Management Guide Prohibited and Restricted Chemical List Following is a table of chemicals that are Prohibited—banned, Restricted—academic curriculum use, and Restricted—demonstration use only. -
Basic Description for Ground and Air Hazardous
BASIC DESCRIPTION FOR GROUND AND AIR GROUND AND AIR HAZARDOUS MATERIALS SHIPMENTS GROUND SHIPMENTS AIR SHIPMENTS SHIPMENTS HAZARD DOT DOT CLASS OR MAXIMUM EXEMPTION, GROUND EXEMPTION, HAZARDOUS MATERIALS DESCRIPTIONS DIVISION I.D. NUMBER LABEL(S) REQUIRED OR QUANTITY PER SPECIAL SERVICE TO LABEL(S) REQUIRED OR MAXIMUM NET CARGO SPECIAL NON-BULK AND PROPER SHIPPING NAME (Subsidiary if (ALSO MARK PACKING EXEMPTION, SPECIAL PERMIT INNER PERMIT CANADA EXEMPTION, SPECIAL PERMIT QUANTITY PER AIRCRAFT PERMIT SPECIAL EXCEPTIONS PACKAGING (ALSO MARK ON PACKAGE) applicable) ON PACKAGE) GROUP OR EXCEPTION RECEPTACLE OR 173.13 PERMITTED OR EXCEPTION PACKAGE** QUANTITY OR 173.13 PROVISIONS §173.*** §173.*** (1) (2) (3) (4) (5) (6) (7) (8) (9) (10) (11) (12) (13) (14) (15) Accellerene, see p-Nitrosodimethylaniline Accumulators, electric, see Batteries, wet etc Accumulators, pressurized, pneumatic or hydraulic (containing non-flammable gas), see Articles pressurized, pneumatic or hydraulic (containing non-flammable gas) FLAMMABLE FLAMMABLE Acetal 3 UN1088 II LIQUID * YES LIQUID * 5 L 150 202 FLAMMABLE Acetaldehyde 3 UN1089 I LIQUID YES Forbidden None 201 May not be regulated when shipped via UPS Acetaldehyde ammonia 9 UN1841 III ground YES CLASS 9 * 30 kg 30 kg 155 204 FLAMMABLE FLAMMABLE Acetaldehyde oxime 3 UN2332 III LIQUID * YES LIQUID * 25 L 150 203 CORROSIVE, CORROSIVE, Acetic acid, glacial or Acetic acid solution, FLAMMABLE FLAMMABLE A3, A6, with more than 80 percent acid, by mass 8 (3) UN2789 II LIQUID * YES LIQUID * 1 L A7, A10 154 202 Acetic -
Combined Pre-And Posttreatment of Paraoxon Exposure
molecules Article Combined Pre- and Posttreatment of Paraoxon Exposure Dietrich E Lorke 1,2,* , Syed M Nurulain 3 , Mohamed Y Hasan 4, Kamil Kuˇca 5 and Georg A Petroianu 2,6 1 Department of Anatomy and Cellular Biology, College of Medicine and Health Sciences, Khalifa University, P O Box 127788, Abu Dhabi, UAE 2 Herbert Wertheim College of Medicine, Department of Cellular Biology & Pharmacology, Florida International University, University Park GL 495, 11200 SW 8th St, Miami, FL 33199, USA; [email protected] 3 Bio Science Department, COMSATS Institute of Information Technology, Bio Sciences Block, CUI, Park Road, Tarlai Kalan, Islamabad 45550, Pakistan; [email protected] 4 Department of Pharmacology & Therapeutics, College of Medicine and Health Sciences, UAE University, Al Ain 15551, UAE; [email protected] 5 Department of Chemistry, Faculty of Science, University of Hradec Kralove, Rokitanského 62/26, 500 03 Hradec Kralove, Czech Republic; [email protected] 6 Department of Pharmacology, College of Medicine and Health Sciences, Khalifa University, P O Box 127788, Abu Dhabi, UAE * Correspondence: [email protected]; Tel.: +971-2-501-8381 Academic Editors: Pascal Houzé and Frédéric J. Baud Received: 5 March 2020; Accepted: 25 March 2020; Published: 27 March 2020 Abstract: Aims: Organophosphates (OPCs), useful agents as pesticides, also represent a serious health hazard. Standard therapy with atropine and established oxime-type enzyme reactivators is unsatisfactory. Experimental data indicate that superior therapeutic results can be obtained when reversible cholinesterase inhibitors are administered before OPC exposure. Comparing the protective efficacy of five such cholinesterase inhibitors (physostigmine, pyridostigmine, ranitidine, tacrine, or K-27), we observed best protection for the experimental oxime K-27. -
Biosensors for Detection of Organophosphate Exposure by New Diethyl Thiophosphate-Specifc Aptamer
Biosensors for Detection of Organophosphate Exposure by New Diethyl Thiophosphate-Specic Aptamer Napachanok Mongkoldhumrongkul Swainson Kasetsart University - Bangkhen Campus: Kasetsart University Chonnikarn Saikaew Kasetsart University - Bangkhen Campus: Kasetsart University Kanyanat Theeraraksakul Kasetsart University - Bangkhen Campus: Kasetsart University Pongsakorn Aiemderm Kasetsart University - Bangkhen Campus: Kasetsart University Rimdusit Pakjira Department of Disease Control Charoenkwan Kraiya Chula: Chulalongkorn University Sasimanas Unajak Kasetsart University - Bangkhen Campus: Kasetsart University kiattawee choowongkomon ( [email protected] ) Kasetsart University https://orcid.org/0000-0002-2421-7859 Research Article Keywords: Aptasensor, organophosphate metabolites, diethyl thiophosphate, electrochemical impedance spectroscopy, capillary electrophoresis Posted Date: February 23rd, 2021 DOI: https://doi.org/10.21203/rs.3.rs-217995/v1 License: This work is licensed under a Creative Commons Attribution 4.0 International License. Read Full License Version of Record: A version of this preprint was published at Biotechnology Letters on July 6th, 2021. See the published version at https://doi.org/10.1007/s10529-021-03158-2. Page 1/17 Abstract Objective An aptamer specically binding to diethyl thiophosphate (DETP) was constructed and incorporated in an optical sensor and electrochemical impedance spectroscopy (EIS) to enable the specic measurement of DETP as a metabolite and a biomarker of exposure to organophosphates. Results DETP-bound aptamer was selected from the library using capillary electrophoresis-systematic evolution of ligands by exponential enrichment (CE-SELEX). A colorimetric method revealed the aptamer had the highest anity to DETP with a mean Kd value (± SD) of 0.103 ± 0.014 µM. Changes in resistance using EIS showed selectivity of the aptamer for DETP higher than for dithiophosphate (DEDTP) and diethyl phosphate (DEP) which have similar structure and are metabolites of some of the same organophosphates. -
Optimization of Photochemical Decomposition Acetamiprid
Toolabi et al. AMB Expr (2017) 7:159 DOI 10.1186/s13568-017-0455-5 ORIGINAL ARTICLE Open Access Optimization of photochemical decomposition acetamiprid pesticide from aqueous solutions and efuent toxicity assessment by Pseudomonas aeruginosa BCRC using response surface methodology Ali Toolabi1, Mohammad Malakootian2,3, Mohammad Taghi Ghaneian1*, Ali Esrafli4, Mohammad Hassan Ehrampoush1, Maesome Tabatabaei5 and Mohsen AskarShahi6 Abstract Contamination of water resources by acetamiprid pesticide is considered one of the main environmental problems. The aim of this study was the optimization of acetamiprid removal from aqueous solutions by TiO2/Fe3O4/SiO2 nanocomposite using the response surface methodology (RSM) with toxicity assessment by Pseudomonas aeruginosa BCRC. To obtain the optimum condition for acetamiprid degradation using RSM and central composite design (CCD). The magnetic TiO2/Fe3O4/SiO2 nanocomposite was synthesized using co-precipitation and sol–gel methods. The surface morphology of the nanocomposite and magnetic properties of the as-synthesized Fe 3O4 nanoparticles were characterised by scanning electron microscope and vibrating sample magnetometer, respectively. In this study, toxic- ity assessment tests have been carried out by determining the activity of dehydrogenase enzyme reducing Resazurin (RR) and colony forming unit (CFU) methods. According to CCD, quadratic optimal model with R2 0.99 was used. By analysis of variance, the most efective values of each factor were determined in each experiment.= According to the results, the most optimal conditions for removal efciency of acetamiprid (pH 7.5, contact time 65 min, and = = dose of nanoparticle 550 mg/L) was obtained at 76.55%. Efect concentration (EC 50) for RR and CFU test were 1.950 and 2.050 mg/L, respectively. -
Organophosphate and Carbamate Pesticides
ORGANOPHOSPHATE AND CARBAMATE PESTICIDES What are ORGANOPHOSPHATE and CARBAMATE PESTICIDES? Organophosphates are phosphoric acid esters or thiophosphoric acid esters. When developed in the 1930s and 1940s, their original compounds were highly toxic to mammals. Organophosphates manufactured since then are less toxic to mammals but toxic to target organisms, such as insects. Malathion, dibrom, chlorpyrifos, temephos, diazinon and terbufos are organophosphates. Carbamates are esters of N-methyl carbamic acid. Aldicarb, carbaryl, propoxur, oxamyl and terbucarb are carbamates. Although these pesticides differ chemically, they act similarly. When applied to crops or directly to the soil as systemic insecticides, organophosphates and carbamates generally persist from only a few hours to several months. However, they have been fatal to large numbers of birds on turf and in agriculture, and negatively impacted breeding success in birds. Many organophosphates are highly toxic to aquatic organisms. How can people be exposed to organophosphate and carbamate pesticides? People can be exposed to organophosphates and carbamates pesticides through accidental exposure during use. People can accidentally inhale the pesticides if they are in an area where they were recently applied. The chemicals can be ingested with food or drinks that are contaminated. How can these pesticides exhaust affect my health? Acetylcholinesterase is an enzyme found in the nervous system, red blood cells and blood plasma. These pesticides damage nerve function by acting as acetylcholinesterase inhibitors in the nervous system. Breathing - Short-term exposure can produce muscle twitching, headache, nausea, dizziness, loss of memory, weakness, tremor, diarrhea, sweating, salivation, tearing, constriction of pupils, and slowed heartbeat. Long-term exposure can produce delayed neurotoxicity, such as tingling and burning in the extremities. -
Insecticides
fY)I\) -;; ooo 3tfJ INSECTICIDES Extension Bulletin 387-Revlsed 1980 AGAfCULTURAL EXTENSION SERVICE UNIVERSITY OF MINNESOTA Contents General precautions for using pesticides . 4 Safety precautions and first aid . 4 Minnesota poison information centers . 5 Protecting honey bees from insecticides . 6 Pesticide toxicity and LD 50's . • . • . 6 Acute oral and dermal LD 50's for insecticides . 7 Forms of insecticides . 8 Calculating dosage and rates of application . 9 Sprayer calibration . 11 Description of insecticides, miticides ........................... 12 Chlorinated hydrocarbons ................................. 12 Carbamates .............................................. 13 Organophosphates ........................................ 14 Sulfonates, carbonates, botanicals, and miscellaneous groups ... 18 Legal Restrictions on Use of Pesticides The Federal Insecticide, Fungicide and Rodenticide Act and the Minnesota Pesticide Act of 1976, require that those who use or supervise the use of certain pesticides with restricted uses must be certified. The labels of those pesticides with restricted uses will contain information regarding these restrictions. Be sure to read all labels thoroughly and use any pesticide for the crops and pests listed on the label only. Information about applicator certification may be obtained from your County Extension Director or the Minnesota Depmt ment of Agriculture. The U.S. Environmental Protection Agency (EPA) has designated the following pesticides for reshicted use: acrolein endrin mevinphos (Phosdrin) acrylonitrile ethyl parathion paraquat aldicarb (Temik) 1080 piclorarri (Tordon) allyl alcohol 1081 sodium cyanide alluminum phosphide (Phostoxin) hydrocyanic acid strychnine azinphos methyl (Guthion) methomyl (Lannate, Nudrin) sulfotepp calcium cyanide methyl bromide tepp demeton (Systox) methyl parathion Authors of this publication are J. A. Lofgren, professor and extension entomologist; D. M. Noetzel, assistant professor and extension entomologist; P. K. Hareln, professor and extension entomologist; M. -
Fairtrade Prohibited Materials List
Fairtrade Prohibited Materials List The Prohibited Materials List (PML) is divided in two lists: the Red List and the Amber List. Red List The Red List includes materials that must not be used by producers while handling Fairtrade products. Handling means all activities that producers are involved in, such as production, post- harvest treatment, processing, storage and transportation. Amber List The Amber List includes materials which are being evaluated by Fairtrade International as candidates to be prohibited by inclusion into the Red List. Materials from the Amber List can still be used by producers for Fairtrade crops. Producers must report their use for monitoring purposes. Monitoring will last for 3 years until 2015, by which date a revision of the Red and Amber lists will be made. Producers should be aware that these materials may eventually be prohibited and are encouraged to abandon their use. Structure of the Red and Amber List The lists contain the following information: Substance: specifies the name of the material Reference list: shows in 7 columns the international list or regulation from where Fairtrade International has taken the material. The reference lists are: POP: The Stockholm Convention on Persistent Organic Pollutants PIC: The Rotterdam Convention on the Prior Information Consent Procedure for Certain Hazardous Chemicals and Pesticides in International Trade PAN 12: Pesticide Action Network’s “dirty dozen” list (currently 18 pesticides) WHO 1a and 1b: World Health Organization Acute toxicity classification Ia and Ib EU: Banned or severely restricted in the European Union according to PAN List of Lists US: Banned or severely restricted pesticide EPA according to PAN List of Lists Specific regulations in the Red List These provide information for specific use of materials and include: Derogation possible and required prior to use: The material must not be used unless a derogation is granted by the certification body. -
Organophosphate and N-Methyl Carbamate 03-12-2010.Xlsx
Product Name EPA Reg. No. Ingredients Registrant Signal Word AgriSolutions Actellic 5E 1381‐170 Pirimiphos‐methyl Winfield Solutions, LLC Danger Insecticide AgriSolutions Dimate 4E 9779‐273 Dimethoate Winfield Solutions, LLC Warning AgriSolutions Dimate 4EC 51036‐110‐9779 Dimethoate Winfield Solutions, LLC Warning Systemic Insecticide AgriSolutions Malathion 5 9779‐5 Malathion Winfield Solutions, LLC Warning AgriSolutions Phorate 20G 9779‐293 Phorate Winfield Solutions, LLC Danger/Poison AgriSolutions Yuma 4E Insecticide 62719‐220‐1381 Chlorpyrifos Winfield Solutions, LLC Warning Azinphosmethyl 50W Soluble 66330‐233 AZM (Azinphos‐methyl) Arysta LifeScience North America, LLC Danger/Poison Carzol SP Insecticide in Water 10163‐265 Formetanate hydrochloride Gowan Company Danger/Poison Soluble Packaging Chemathoate Technical 4787‐7 Dimethoate Cheminova Inc [Third Party: Lewis & Harrison LLC] Warning Cheminova Dimethoate 4E 34704‐207‐67760 Dimethoate Cheminova Inc [Third Party: Lewis & Harrison LLC] Warning Cheminova Methyl 4EC 67760‐43 Methyl parathion Cheminova Inc [Third Party: Lewis & Harrison LLC] Danger/Poison Chlorpyrifos 4E AG 66222‐19 Chlorpyrifos Makhteshim‐Agan of North America Inc Warning Chlorpyrifos 4E AG 66330‐278 Chlorpyrifos Arysta LifeScience North America, LLC Warning Cobalt Insecticide 62719‐575 Chlorpyrifos, Gamma‐ Dow AgroSciences Inc Danger cyhalothrin Counter 15G Lock'n Load 5481‐545 Terbufos Amvac Chemical Corporation Danger/Poison Counter 15G Smartbox Systemic 5481‐545 Terbufos Amvac Chemical Corporation Danger/Poison -
150 Subpart A—General Subpart B—Table of Hazardous Materials
§ 172.1 49 CFR Ch. I (10–1–19 Edition) APPENDIX B TO PART 172—TREFOIL SYMBOL shipping name. In addition, the Table APPENDIX C TO PART 172—DIMENSIONAL SPEC- specifies or references requirements in IFICATIONS FOR RECOMMENDED PLACARD this subchapter pertaining to labeling, HOLDER packaging, quantity limits aboard air- APPENDIX D TO PART 172—RAIL RISK ANAL- YSIS FACTORS craft and stowage of hazardous mate- rials aboard vessels. AUTHORITY: 49 U.S.C. 5101–5128, 44701; 49 CFR 1.81, 1.96 and 1.97. (b) Column 1: Symbols. Column 1 of the Table contains six symbols (‘‘ + ’’, ‘‘A’’, SOURCE: Amdt. 172–29, 41 FR 15996, Apr. 15, ‘‘D’’, ‘‘G’’, ‘‘I’’ and ‘‘W’’) as follows: 1976, unless otherwise noted. (1) The plus (+) sign fixes the proper shipping name, hazard class and pack- Subpart A—General ing group for that entry without regard to whether the material meets the defi- § 172.1 Purpose and scope. nition of that class, packing group or This part lists and classifies those any other hazard class definition. When materials which the Department has the plus sign is assigned to a proper designated as hazardous materials for shipping name in Column (1) of the purposes of transportation and pre- § 172.101 Table, it means that the mate- scribes the requirements for shipping rial is known to pose a risk to humans. papers, package marking, labeling, and When a plus sign is assigned to mix- transport vehicle placarding applicable tures or solutions containing a mate- to the shipment and transportation of rial where the hazard to humans is sig- those hazardous materials. -
Registration Division Conventional Pesticides -Branch and Product
Registration Division Conventional Pesticides - Branch and Product Manager (PM) Assignments For a list of Branch contacts, please click the following link: http://www2.epa.gov/pesticide-contacts/contacts-office-pesticide-programs-registration-division Branch FB=Fungicide Branch. FHB=Fungicide Herbicide Branch. HB=Herbicide Branch. Abbreviations: IVB*= Invertebrate-Vertebrate Branch 1, 2 or 3. MUERB=Minor Use and Emergency Response Branch. Chemical Branch PM 1-Decanol FHB RM 20 1-Naphthaleneacetamide FHB RM 20 2, 4-D, Choline salt HB RM 23 2,4-D HB RM 23 2,4-D, 2-ethylhexyl ester HB RM 23 2,4-D, butoxyethyl ester HB RM 23 2,4-D, diethanolamine salt HB RM 23 2,4-D, dimethylamine salt HB RM 23 2,4-D, isopropyl ester HB RM 23 2,4-D, isopropylamine salt HB RM 23 2,4-D, sodium salt HB RM 23 2,4-D, triisopropanolamine salt HB RM 23 2,4-DB HB RM 23 2,4-DP HB RM 23 2,4-DP, diethanolamine salt HB RM 23 2,4-DP-p HB RM 23 2,4-DP-p, 2-ethylhexyl ester FB RM 21 2,4-DP-p, DMA salt HB RM 23 2-EEEBC FB RM 21 2-Phenylethyl propionate FHB RM 20 4-Aminopyridine IVB3 RM 07 4-Chlorophenoxyacetic acid FB RM 22 4-vinylcyclohexene diepoxide IVB3 RM 07 Abamectin IVB3 RM 07 Acephate IVB2 RM 10 Acequinocyl IVB3 RM 01 Acetaminophen IVB3 RM 07 Acetamiprid IVB3 RM 01 Acetic acid, (2,4-dichlorophenoxy)-, compd. with methanamine (1:1) HB RM 23 Acetic acid, trifluoro- FHB RM 20 Acetochlor HB RM 25 Acibenzolar-s-methyl FHB RM 24 Acid Blue 9 HB RM 23 Acid Yellow 23 HB RM 23 Sunday, June 06, 2021 Page 1 of 17 Chemical Branch PM Acifluorfen HB RM 23 Acrinathrin IVB1 RM 03