Evidence-Based Management of Third Molar Teeth Presentation
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Applications of Cytokeratin Expression in the Diagnosis of Oral Diseases
Jemds.com Review Article Applications of Cytokeratin Expression in the Diagnosis of Oral Diseases Archana Sonone1, Alka Hande2, Madhuri Gawande3,Swati Patil4 1, 2, 3, 4 Department of Oral Pathology and Microbiology, Sharad Pawar Dental College, Datta Meghe Institute of Medical Sciences (Deemed to Be University) Sawangi (Meghe), Wardha, Maharashtra, India. ABSTRACT All mammalian cells have a complex intracytoplasmic cytoskeleton made up of three Corresponding Author: main structural units and related proteins, tubulin containing microtubules, actin Dr. Archana Sonone. Department of Oral Pathology and containing microfilaments, and Intermediate Filaments (IF). There are six types of Microbiology, Sharad Pawar Dental IFs; cytokeratin fibres consisting of type I and type II IFs. Cytokeratins (CK), College, Datta Meghe Institute of Medical . comprising of collections of IFs that are explicitly communicated by epithelial tissues Sciences (Deemed to Be University) There are 20 unique polypeptides of CK expressed by epithelium that have been Sawangi (Meghe), Wardha, Maharashtra, indexed based on their molecular weight (range 40-70 kDa). India. CK and associated filaments give a framework to epithelial cells and tissues to E-mail: [email protected] maintain their structural integrity. Thus, ensure mechanical resilience, sustain stress, establish cell polarity, and to protect against variations in hydrostatic pressure. DOI: 10.14260/jemds/2021/50 Genetic encoding of cytokeratins shows homogeneous “nucleotide sequence”. 54 How to Cite This Article: genes are responsible for encoding of cytokeratin in humans which are congregated Sonone A, Hande A, Gawande M, et al. on chromosome no. 2. Genetic mutation of cytokeratins is important for Applications of cytokeratin expression in pathophysiology of various mucocutaneous disorders, which is mostly autosomal the diagnosis of oral diseases. -
Tooth Size Proportions Useful in Early Diagnosis
#63 Ortho-Tain, Inc. 1-800-541-6612 Tooth Size Proportions Useful In Early Diagnosis As the permanent incisors begin to erupt starting with the lower central, it becomes helpful to predict the sizes of the other upper and lower adult incisors to determine the required space necessary for straightness. Although there are variations in the mesio-distal widths of the teeth in any individual when proportions are used, the sizes of the unerupted permanent teeth can at least be fairly accurately pre-determined from the mesio-distal measurements obtained from the measurements of already erupted permanent teeth. As the mandibular permanent central breaks tissue, a mesio-distal measurement of the tooth is taken. The size of the lower adult lateral is obtained by adding 0.5 mm.. to the lower central size (see a). (a) Width of lower lateral = m-d width of lower central + 0.5 mm. The sizes of the upper incisors then become important as well. The upper permanent central is 3.25 mm.. wider than the lower central (see b). (b) Size of upper central = m-d width of lower central + 3.25 mm. The size of the upper lateral is 2.0 mm. smaller mesio-distally than the maxillary central (see c), and 1.25 mm. larger than the lower central (see d). (c) Size of upper lateral = m-d width of upper central - 2.0 mm. (d) Size of upper lateral = m-d width of lower central + 1.25 mm. The combined mesio-distal widths of the lower four adult incisors are four times the width of the mandibular central plus 1.0 mm. -
Iii Bds Oral Pathology and Microbiology
III BDS ORAL PATHOLOGY AND MICROBIOLOGY Theory: 120 Hours ORAL PATHOLOGY MUST KNOW 1. Benign and Malignant Tumours of the Oral Cavity (30 hrs) a. Benign tumours of epithelial tissue origin - Papilloma, Keratoacanthoma, Nevus b. Premalignant lesions and conditions: - Definition, classification - Epithelial dysplasia - Leukoplakia, Carcinoma in-situ, Erythroplakia, Palatal changes associated with reverse smoking, Oral submucous fibrosis c. Malignant tumours of epithelial tissue origin - Basal Cell Carcinoma, Epidermoid Carcinoma (Including TNM staging), Verrucous carcinoma, Malignant Melanoma. d. Benign tumours of connective tissue origin : - Fibroma, Giant cell Fibroma, Peripheral and Central Ossifying Fibroma, Lipoma, Haemangioma (different types). Lymphangioma, Chondroma, Osteoma, Osteoid Osteoma, Benign Osteoblastoma, Tori and Multiple Exostoses. e. Tumour like lesions of connective tissue origin : - Peripheral & Central giant cell granuloma, Pyogenic granuloma, Peripheral ossifying fibroma f. Malignant Tumours of Connective tissue origin : - Fibrosarcoma, Chondrosarcoma, Kaposi's Sarcoma Ewing's sarcoma, Osteosarcoma Hodgkin's and Non Hodgkin's L ymphoma, Burkitt's Lymphoma, Multiple Myeloma, Solitary Plasma cell Myeloma. g. Benign Tumours of Muscle tissue origin : - Leiomyoma, Rhabdomyoma, Congenital Epulis of newborn, Granular Cell tumor. h. Benign and malignant tumours of Nerve Tissue Origin - Neurofibroma & Neurofibromatosis-1, Schwannoma, Traumatic Neuroma, Melanotic Neuroectodermal tumour of infancy, Malignant schwannoma. i. Metastatic -
Third Molar (Wisdom) Teeth
Third molar (wisdom) teeth This information leaflet is for patients who may need to have their third molar (wisdom) teeth removed. It explains why they may need to be removed, what is involved and any risks or complications that there may be. Please take the opportunity to read this leaflet before seeing the surgeon for consultation. The surgeon will explain what treatment is required for you and how these issues may affect you. They will also answer any of your questions. What are wisdom teeth? Third molar (wisdom) teeth are the last teeth to erupt into the mouth. People will normally develop four wisdom teeth: two on each side of the mouth, one on the bottom jaw and one on the top jaw. These would normally erupt between the ages of 18-24 years. Some people can develop less than four wisdom teeth and, occasionally, others can develop more than four. A wisdom tooth can fail to erupt properly into the mouth and can become stuck, either under the gum, or as it pushes through the gum – this is referred to as an impacted wisdom tooth. Sometimes the wisdom tooth will not become impacted and will erupt and function normally. Both impacted and non-impacted wisdom teeth can cause problems for people. Some of these problems can cause symptoms such as pain & swelling, however other wisdom teeth may have no symptoms at all but will still cause problems in the mouth. People often develop problems soon after their wisdom teeth erupt but others may not cause problems until later on in life. -
Unusual Anatomy of a Second Maxillary Molar - a Rare Four- Root Configuration Case Report
ARC Journal of Dental Science Volume 1, Issue 2, 2016, PP 13-15 ISSN No. (Online): 2456-0030 http://dx.doi.org/10.20431/2456-0030.0102003 www.arcjournals.org Unusual Anatomy of a Second Maxillary Molar - a Rare four- Root Configuration Case Report Dr. Thiago de Almeida Prado Naves Carneiro,DDS, MSc PhD student, Department of Occlusion, Fixed Prostheses, and Dental Materials, School of Dentistry, Universidade Federal de Uberlândia, Uberlândia, Minas Gerais Brazil. [email protected] Abstract: Although it is a very rare situation, four-rooted maxillary second molars can occur. The existence of two palatal roots is extremely rare and ranges about only 0.4%. The aim of this study is to present and document a very rare anatomic configuration of a four-rooted maxillary second molar. Anatomic variation in the number of roots and root canals can occur in any tooth, although some cases can be extremely rare as the one presented here.Clinicians should be aware of this possibility before considering any kind of treatment. Keywords: Molar, Dental Anatomy, Anatomical Variation 1. INTRODUCTION Usually the maxillary second molars are described in the literature as a teeth that have 3 roots with 3 or 4 root canals. Understanding of the presence of additional roots and unusual root canals is essential and determines the success of endodontic treatment1. The existence of maxillary second molars with 4 roots (2 buccal and 2 palatal) is extremely rare and ranges about only 0.4%.This information comes from a study that showed, after the examination of two different horizontally angled radiographs of 1,000 maxillary second molars, just four with four roots2. -
Two Sets of Teeth in a Lifetime
Two sets of teeth in a lifetime Two sets of teeth in a lifetime Deciduous teeth: They are the first set of teeth we have and there are altogether 20 of them. They usually start to erupt from around the age of six months until 3 years of age. Permanent teeth: At the age of 6, they sequentially erupt to replace the deciduous teeth which become loose and shed. Deciduous teeth: Space retainer for permanent teeth Normally, underneath the root of each deciduous tooth, there is a developing permanent successor tooth. When it is time for the permanent successor tooth to erupt, the root of the deciduous tooth will resorb and the deciduous tooth will become loose. The place is then taken up by its permanent successor tooth. Deciduous tooth retains the space for its permanent successor tooth. No tooth is dispensable If the deciduous tooth, especially the second deciduous molar, is lost early due to tooth decay, the consequences can be serious: Poor alignment of the teeth The second deciduous molar is already lost The first permanent molar Since the first permanent molar erupts behind the second deciduous molar at the age of 6, the space of the lost second deciduous molar will gradually close up as the first permanent molar moves forward. The permanent tooth is crowded out of the arch when it erupts Later, when the second permanent premolar erupts to replace the second deciduous molar, the permanent tooth will either be crowded out of the dental arch or be impacted and is unable to erupt, leading to poor alignment of the teeth. -
A Comparative Study of One Implant Versus Two Replacing a Single Molar Thomas J
JOMI on CD-ROM, 1996 Mar (372-378 ): A Comparative Study of One Implant Versus … Copyrights © 1997 Quinte… A Comparative Study of One Implant Versus Two Replacing a Single Molar Thomas J. Balshi, DDS, FACP/Ramon E. Hernandez, DMD/Maria Claudia Pryszlak, DMD/Bo Rangert, PhD, MechEng A comparative study between one and two Brånemark implants replacing a single molar was conducted. Forty-seven individuals comprised two groups of 22 patients treated with one implant and 25 with two implants. A total of 72 implants were placed, 66 (92%) in the mandible and six (8%) in the maxilla. After the first year of function, the success rate was 99%, with only one implant lost. Between the second- and third-year follow-ups, 100% of the implants continued to function in the remaining 46 patients, giving a 3-year cumulative success rate of 99%. The marginal bone loss between 1 and 3 years of function was 0.10 mm (SD 0.20) for the group with one implant and 0.24 mm (SD 0.20) for the group with two implants. No changes were observed in the Sulcus Bleeding Index during the 3-year follow-up. Prosthesis mobility or screw loosening was the most frequent complication and was predominant in the group using one implant (48%), but was substantially reduced in the group using two implants (8%). These mechanical problems, using one implant only, seem to be preventable using a stronger screw joint (CeraOne abutment). Precise centric occlusal contact was established and maintained over the study period, which was thought to contribute to the very high success rate for the single-implant-supported molars, despite their high degree of mechanical problems. -
Oral Pathology and Oral Microbiology
3.3.2 SYLLABUS ( Including Teaching Hours.) MUST KNOW 109 HRS 1 Developmental Disturbances of oral and paraoral structures 03 HRS Developmental disturbances of hard tissues: -dental arch relations, -disturbances related to - -size,shape,number and structure of teeth, -disturbances related to eruption and shedding. Developmental disturbances of soft tissues: Lip,palate,oral mucosa,gingival,tongue and salivary glands Craniofacial anomalies 2 Benign and Malignant tumors of oral cavity 25 HRS Potentially Malignant Disorders of epithelial tissue origin. -Definitions and nomenclature -Epithelial dysplasia -Lesions and conditions:leukoplakia, erythroplakia,oral lichen planus and oral submucous fibrosis. Benign tumors of epithelial tissue origin. - Squamous papilloma, Oral nevi. Malignant tumors of epithelial tissue origin. -Oral squamous cell carcinoma: Definition and nomenclature,etiopathogenesis, TNM staging ,Broder’s and Bryne’s grading systems. -Verrucous carcinoma -Basal cell carcinoma: Definition etiopathogenesis and histopathology -Malignant melanoma: Definition etiopathogenesis and histopathology Benign and malignant tumors of connective tissue -Fibroblast origin:oral fibromas and fibromatosis,peripheral ossifying fibroma peripheral giant cell granuloma, pyogenic granuloma and Fibrosarcoma -Adipose tissue origin:Lipoma -Endothelial origin(blood and lymphatics: Hemangiomas and lymphangiomas, Hereditary hemorrhagic telangiactasia, Kaposi’s sarcoma Bone and cartilage: Chondroma,osteoma,osteoid osteoma, benign osteoblastoma, osteosarcoma, -
Oral Pathology Final Exam Review Table Tuanh Le & Enoch Ng, DDS
Oral Pathology Final Exam Review Table TuAnh Le & Enoch Ng, DDS 2014 Bump under tongue: cementoblastoma (50% 1st molar) Ranula (remove lesion and feeding gland) dermoid cyst (neoplasm from 3 germ layers) (surgical removal) cystic teratoma, cyst of blandin nuhn (surgical removal down to muscle, recurrence likely) Multilocular radiolucency: mucoepidermoid carcinoma cherubism ameloblastoma Bump anterior of palate: KOT minor salivary gland tumor odontogenic myxoma nasopalatine duct cyst (surgical removal, rare recurrence) torus palatinus Mixed radiolucencies: 4 P’s (excise for biopsy; curette vigorously!) calcifying odontogenic (Gorlin) cyst o Pyogenic granuloma (vascular; granulation tissue) periapical cemento-osseous dysplasia (nothing) o Peripheral giant cell granuloma (purple-blue lesions) florid cemento-osseous dysplasia (nothing) o Peripheral ossifying fibroma (bone, cartilage/ ossifying material) focal cemento-osseous dysplasia (biopsy then do nothing) o Peripheral fibroma (fibrous ct) Kertocystic Odontogenic Tumor (KOT): unique histology of cyst lining! (see histo notes below); 3 important things: (1) high Multiple bumps on skin: recurrence rate (2) highly aggressive (3) related to Gorlin syndrome Nevoid basal cell carcinoma (Gorlin syndrome) Hyperparathyroidism: excess PTH found via lab test Neurofibromatosis (see notes below) (refer to derm MD, tell family members) mucoepidermoid carcinoma (mixture of mucus-producing and squamous epidermoid cells; most common minor salivary Nevus gland tumor) (get it out!) -
CHAPTER 5Morphology of Permanent Molars
CHAPTER Morphology of Permanent Molars Topics5 covered within the four sections of this chapter B. Type traits of maxillary molars from the lingual include the following: view I. Overview of molars C. Type traits of maxillary molars from the A. General description of molars proximal views B. Functions of molars D. Type traits of maxillary molars from the C. Class traits for molars occlusal view D. Arch traits that differentiate maxillary from IV. Maxillary and mandibular third molar type traits mandibular molars A. Type traits of all third molars (different from II. Type traits that differentiate mandibular second first and second molars) molars from mandibular first molars B. Size and shape of third molars A. Type traits of mandibular molars from the buc- C. Similarities and differences of third molar cal view crowns compared with first and second molars B. Type traits of mandibular molars from the in the same arch lingual view D. Similarities and differences of third molar roots C. Type traits of mandibular molars from the compared with first and second molars in the proximal views same arch D. Type traits of mandibular molars from the V. Interesting variations and ethnic differences in occlusal view molars III. Type traits that differentiate maxillary second molars from maxillary first molars A. Type traits of the maxillary first and second molars from the buccal view hroughout this chapter, “Appendix” followed Also, remember that statistics obtained from by a number and letter (e.g., Appendix 7a) is Dr. Woelfel’s original research on teeth have been used used within the text to denote reference to to draw conclusions throughout this chapter and are the page (number 7) and item (letter a) being referenced with superscript letters like this (dataA) that Treferred to on that appendix page. -
Mammalian Molar Complexity Follows Simple, Predictable Patterns
Mammalian molar complexity follows simple, predictable patterns Keegan R. Seliga,1, Waqqas Khalida, and Mary T. Silcoxa aDepartment of Anthropology, University of Toronto Scarborough, Toronto, ON M1C 1A4, Canada Edited by Nils Chr. Stenseth, University of Oslo, Oslo, Norway, and approved November 19, 2020 (received for review May 4, 2020) Identifying developmental explanations for the evolution of com- been demonstrated that there are strong genetic controls that plex structures like mammalian molars is fundamental to studying account for the developmental cascade, with research linking the phenotypic variation. Previous study showed that a “morphoge- ICM and the sonic hedgehog (Shh) gene, among others (10). It netic gradient” of molar proportions was explained by a balance should be noted that there are cases where the ICM does between inhibiting/activating activity from earlier developing mo- not seem to account for molar size covariation. For example, lars, termed the inhibitory cascade model (ICM). Although this Roseman and Delezene (11) found that gorillas do not meet any model provides an explanation for variation in molar proportions, of the predictions of the ICM, and Carter and Worthington (12) what remains poorly understood is if molar shape, or specifically demonstrate that some hominoids and cercopithecins do not complexity (i.e., the number of cusps, crests), can be explained by meet all of the predictions either. However, Evans et al. (2) also the same developmental model. Here, we show that molar com- analyzed the ICM in apes and hominids and considered both the plexity conforms to the ICM, following a linear, morphogenetic deciduous premolars and a reversal of the inhibitory cascade gradient along the molar row. -
Identifying Features
Permanent maxillary second molar Dental Anatomy .د ـــن ا Lec.Lec.12121212 Permanent maxillary second molar Principal identifying features: 1. No fifth cusp is evident. 2. Roots are less divergent and may coalescent. 3. Disto-buccal and mesio-buccal cusps are less developed. 4. The crown is smaller in all dimensions than max. first molar. Buccal aspect: 1. The crown is smaller in all dimensions than max. first molar. 2. The disto-buccal cusp is smaller and allows part of distal marginal ridge and part of disto-buccal cusp to be seen. 3. The buccal roots are about the same length. They are nearly parallel and more inclined distally more than that of max. first molar. 4. The palatal root is the longest root (about 1 mm longer than buccal roots). Lingual aspect: 1 Permanent maxillary second molar Dental Anatomy 1. The disto-lingual cusp is smaller than that of max. first molar. 2. No fifth cusp. 3. The apex of palatal root is in a line with disto-lingual cusp tip . Mesial aspect: 1. Bucco-lingual dimension is the same as that of max. first molar but the crown length is smaller. 2. The roots are less divergent bucco-lingually. Distal aspect: The disto-buccal cusp is smaller than that of max. first molar. Occlusal aspect: 1. The crown has rhomboidal shape, with the acute angles are less and the obtuse angles are more than that of max. first molar. 2. The bucco-lingual diameter is the same but the mesio-distal diameter is smaller by about 1 mm than that of max.