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44Th Annual Drosophila Research Conference 55th Annual Drosophila Research Conference 2014 Drosophila Genetics San Diego, California, USA 26 - 30 March 2014 ISBN: 978-1-63266-520-1 Printed from e-media with permission by: Curran Associates, Inc. 57 Morehouse Lane Red Hook, NY 12571 Some format issues inherent in the e-media version may also appear in this print version. Copyright© (2014) by the Genetics Society of America (GSA) All rights reserved. Printed by Curran Associates, Inc. (2014) For permission requests, please contact the Genetics Society of America (GSA) at the address below. Genetics Society of America (GSA) 9650 Rockville Pike Bethesda MD 20814-3998 Phone: (301) 634-7300 Fax: (301) 634-7079 [email protected] Additional copies of this publication are available from: Curran Associates, Inc. 57 Morehouse Lane Red Hook, NY 12571 USA Phone: 845-758-0400 Fax: 845-758-2634 Email: [email protected] Web: www.proceedings.com OPENING AND PLENARY SESSIONS Wednesday, March 26 7:00 PM–9:15 PM Thursday, March 27 8:30 AM–12:00 NOON Opening General Session Plenary Session I Co-Moderators: Mark Van Doren, Johns Hopkins Moderator: Daniela Drummond-Barbosa, Johns University, Baltimore, Maryland and Elissa Lei, Hopkins University, Baltimore, Maryland NIH/National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland Room: Atlas Ballroom Room: Atlas Ballroom Presentations: Presentations: 8:30 am Image Award Presentation. David Bilder. University of California, Berkeley. N/A 7:00 pm Welcome and Opening Remarks. Mark Van Doren. Johns Hopkins University, Baltimore, 8:35 am Controlling Morphogen Gradients. Arthur Maryland. N/A D. Lander. Dept Dev Cell Biol and Dept of Biomedical Engineering, Univ California, Irvine, 7:10 pm GSA Welcome and Update. Adam Fagen. Irvine, CA. pg. 3 Genetics Society of America, Bethesda, Maryland. N/A 9:05 am Fat Cadherins in Growth, Planar Polarity 7:20 pm Larry Sandler Award Presentation. Ken and Mitochondrial Activity. Helen McNeill. Irvine. Rutgers University, Waksman Institute, Lunenfeld-Tanenbaum Institute, Mt Sinai Hospital , Piscataway, New Jersey. N/A Toronto, ON, Canada; Dept. Molecular Genetics, University of Toronto Toronto, Canada. pg. 3 7:25 pm Larry Sandler Lecture. N/A 9:35 am Epigenetic Regulation of Drosophila Male 7:55 pm Keynote Introduction. Elissa Lei. Germ Cell Differentiation. Xin Chen. Dept Biol, NIH/National Institute of Diabetes and Digestive and Johns Hopkins Univ, Baltimore, MD. pg. 3 Kidney Diseases, Bethesda, Maryland. N/A 10:05 am - Break 8:00 pm Science, Biology, and the World’s Future. Bruce Alberts. UCSF, San Francisco, CA. pg. 3 10:30 am X Marks the Spot: Targeting the X Chromosome During Dosage Compensation. Erica 9:00 pm Presentation of George W. Beadle Award N. Larschan. Molec Biol, Cellular Biol & Biochem, to Hugo Bellen, Baylor College of Medicine/HHM). N/A Brown Univ, Providence, RI. pg. 4 11:00 am Circuit Mechanisms Underlying Behavioral Decisions and Motor Program Sequencing in Ecdysis. Benjamin H. White. Laboratory of Molecular Biology, National Institute of Mental Health, Bethesda, MD. pg. 4 11:30 am The Molecular Evolution of Morphology and Behavior. David L. Stern. Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, VA. pg. 4 OPENING AND PLENARY SESSIONS Notes Sunday, March 30 8:30 AM–12:00 NOON Plenary Session II Moderator: Mihaela Serpe, NIH/National Institute of Child Health and Human Development, Bethesda, Maryland Room: Atlas Ballroom Presentations: 8:30 am Poster Award Presentation. Mihaela Serpe. NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland. N/A 8:35 am Charting the Genotype-Phenotype Map: Lessons from Drosophila. Trudy F. Mackay. Dept Biological Sciences, North Carolina State Univ, Raleigh, NC. pg. 5 9:05 am Walking the Highwire from Synaptic Growth to the Axon Injury Response Pathway. Aaron DiAntonio. Dept of Developmental Biology, Washington University School of Medicine, St. Louis, MO. pg. 5 9:35 am piRNAs Function for the Safeguard of Germline Genome. Toshie Kai. Temasek Lifesciences Laboratory/Dept. Biological Science, National University of Singapore, Singapore. pg. 5 10:05 am - Break 10:30 am Multiple Layers of Complexity in the Regulation of the Bithorax Complex. Francois Karch. Dept Genetic and Evolution, Univ Geneva, Geneva, Switzerland. pg. 6 11:00 am Cardiomyopathy Models. Rolf Bodmer. Development and Agi, Sanford-Burnham Medical Research Institute, La Jolla, CA. pg. 6 11:30 am The Conflicted Existence of the Mitochondrial Genome. Patrick H. O'Farrell. Dept Biochemistry, Univ California, San Francisco, CA. pg. 6 CONCURRENT PLATFORM SESSIONS THURSDAY, MARCH 27 4:30-6:30 PM Presenting author is in bold. Full abstracts can be found online. Cell Division and Growth Control Neural Development Co-Moderators: Laura Buttitta, University of Michigan, and Alex Co-Moderators: Robin Hiesinger, UT Southwestern, Dallas, Texas Gould, MRC National Institute for Medical Research, London, UK and James Posakony, University of California, San Diego Room: Town & Country Room: Golden West 1 - 4:30 pg. 7 9 - 4:30 pg. 9 Re-replication during Follicle Cell Gene Amplification causes Chromatin modulation in structural and functional refinement of replication fork instability and requires double-strand break repair. fru+ ORN circuits in Drosophila. Pelin C. Volkan1,2,3, Doug Jessica L. Alexander, Terry L. Orr-Weaver. Whitehead Inst for Olsen1, Catherine Hueston2, Qingyun Li1, Jianni Wu4. 1) Duke Biomedical Research/Dept. of Biology, MIT, Cambridge, MA. University, Department of Biology, Durham, NC; 2) Duke University, Department of Neurobiology, Durham, NC; 3) Duke 2 - 4:45 pg. 7 Institute of Brain Sciences; 4) Duke Univeristy, Undergraduate Regulation of cilium and centrosome function by rootletin. Jieyan Program in Neuroscience, Durham, NC. Chen, Timothy Megraw. Biomedical Sciences, Florida State University, Tallahassee, FL. 10 - 4:45 pg. 10 Intravital 2-photon imaging and computational modeling reveal 3 - 5:00 pg. 7 simple pattern formation rules underlying neural superposition. The Drosophila orthologue of human GOLPH3 is required for Egemen Agi1,5, Marion Langen2,5, Dylan Altschuler2,3, Lani Wu2,4, contractile ring formation and membrane trafficking during Steven Altschuler2,4, Peter Robin Hiesinger1,2,4. 1) Department of cytokinesis. Maria Grazia Giansanti1, Giorgio Belloni2, Gianni Physiology, Univ of Texas Southwestern Med Center, Dallas; 2) Colotti1, Vincenzo Mattei3, Anna Frappaolo1, Grazia Daniela Green Center for Systems Biology, Dept of Pharmacology, Raffa2, Margaret T. Fuller4, Stefano Sechi1. 1) IBPM, Consiglio Simmons Cancer Center, Univ of Texas Southwestern Medical Nazionale delle Ricerche, Rome, Italy; 2) Dipartimento di Biologia Center, Dallas; 3) STARS program, Univ of Texas Southwestern e Biotecnologie, Università Sapienza, Rome, Italy; 3) Laboratory Med Center, Dallas; 4) Co-corresponding; 5) Equal contribution. of Experimental and Environmental Pathology, Sabina Universitas, Rieti, Italy; 4) Departments of Developmental Biology and 11 - 5:00 pg. 10 Genetics, Stanford University School of Medicine, Stanford, USA. Role of microRNA machinery in dendrite patterning. Marvin Nayan1, Charlie Kim2, Jay Parrish1. 1) Dept. of Biology, 4 - 5:15 pg. 8 University of Washington, Seattle, WA; 2) Division of Adenosine is a paracrine homeostatic signal affecting growth of Experimental Medicine, University of California San Francisco, wts tumor clones. Michal Zurovec, Roman Sidorov, Lucie Kucerova. Biology Centre CAS, Ceske Budejovice, Czech 12 - 5:15 pg. 10 Republic. Drosophila Mitofusin affects mitochondrial trafficking, steroid- hormone production and NMJ maturation. Hector Sandoval1, Chi- 5 - 5:30 pg. 8 Kuang Yao1,4, Kuchuan Chen2, Taraka Donti1, Manish Jaiswal3, Growth control by the conserved Aac11/Api5 anti-apoptotic Yong-Qi Lin3,5, Shinya Yamamoto1,2, Brett Graham1, Hugo protein. Can Zhang1, Wenjian Xu2, Alexey Veraksa2, Kenneth Bellen1,2,3. 1) Human and Molecular Genetics; 2) Program in Moberg1. 1) Department of Cell Biology, Emory University, Development Biology; 3) Howard Hughes Medical Institute, Atlanta, GA; 2) Department of Biology, University of BCM, Houston, TX; 4) Academia Sinica, Institute Institute of Massachusetts Boston, Boston, MA. Biological Chemistry, Taipei, Taiwan; 5) Garvan Institute of Medical Research, Neuroscience Program, Sidney, Australia. 6 - 5:45 pg. 8 The Drosophila TNF receptor Grindelwald couples loss of cell 13 - 5:30 pg. 11 polarity with neoplastic growth. Julien Colombani1, Ditte Crimpy enables discrimination of pre and postsynaptic pools of a Andersen1, Krittalak Chakrabandhu1, Michael Röthlisberger2, BMP at the NMJ. Rebecca James1, Kendall Hoover1, Chris Anne-Odile Hueber1, Konrad Basler2, Pierre Leopold1. 1) Wilson1, Kristi Wharton2, Ed Levitan3, Heather Broihier1. 1) University of Nice Sophia Antipolis, CNRS UMR7277, INSERM Neurosciences, Case Western Reserve University, Cleveland, OH; U1091, Intitute of Biology Valrose, Nice, France; 2) Inst of 2) Molecular Biology, Cell Biology, and Biochemistry, Molecular Life Sciences, Univ of Zurich, Zurich, Switzerland. Providence, Brown University, RI; 3) Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA. 7 - 6:00 pg. 9 An evolutionarily conserved role for plexins during epithelial 14 - 5:45 pg. 11 wound repair in Drosophila and zebrafish. Sa Kan Yoo1,2, Iswar Local BMP signaling sculpts synapse development at the Hariharan1. 1) UC-Berkeley, Berkeley, CA; 2) Miller institute, Drosophila
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