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Microbiology Quality Control Introduction

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Microbiology Quality Control Introduction Microbiology Quality Control introduction When left undetected, micro- Content organisms can halt the production 208 Pharmaceutical Quality Control of pharmaceuticals, spoil food, ruin the Application Selector taste of beverages, negatively impact the performance of 209 Beverage Quality Control Application Selector computer chips, and cause serious illness. That’s why Pall is MICROBIOLOGY QUALITY CONTROL 210 Microbiology Quality dedicated to finding new and better ways to help you accurately Control Overview and reliably identify these microorganisms to protect both public 212 Microbiology Quality Control – Online Reference Library safety and the integrity of industrial assets. 213 Microbiology Quality Control Pall has been setting performance standards in Microbiology 213 Products – Membranes Quality Control laboratories for more than 50 years, and our 216 Products – Media products are referenced and recommended by regulatory 218 Products – Filter Funnels agencies worldwide. We invite you to explore the many ways 228 Products – Hardware Pall’s sample prep solutions can enhance your pharmaceutical 230 Products – Accessories and beverage quality control applications. 1. 8 0 0 .5 2 1 . 1 5 2 0 ( U S A and Canada) (+)800.PALL.LIFE (Outside USA and Canada) www.pall.com/lab 207 Pharmaceutical Quality Control Application Selector Membranes Page Number PseudomonasDetection sp. Total BacteriaDetection Total ColiformsDetection Fecal ColiformsDetection Yeast Detectionand Mold GN-6 Metricel® MCE membrane disc filters, S-pack 213 • • • • • Metricel Black PES membrane disc filters, S-pack 214 • • Sentino™ Filter Dispenser 213a • • • • • Supor® 200 PES membrane disc filters, S-pack 215 • • Ampoule Media* HPC with TTC indicator broth 216 • M-FC broth 216 • MF-Endo broth 216 • M-Green YM broth 216 • M-TGE broth 216 • Pseudomonas broth 216 • Trypticase Soy broth - USP 216 • Filter Funnels 47 mm magnetic filter funnels 226 • • • • • MicroFunnel™ filter funnels, 100 and 300 mL 218 • • • • • MicroFunnel Plus filter funnels, 100 and 300 mL 220 • • • • • MicroFunnel ST filter funnels, 100 and 300 mL 222 • • • • • Sentino Magnetic filter funnels 225a • • • • • Vents Vacushield™ vent device 165 • • • • • application selector Hardware and Accessories Absorbent pad kits 231 • • • • • Filter funnel manifolds 229 • • • • • Filter funnel manifolds for MicroFunnel filter funnels 228 • • • • • Petri dishes 230, 280 • • • • • Sentino Microbiology Pump 224 • • • • • Stainless steel forceps 230, 280 • • • • • Vacuum/pressure pumps 279 • • • • • * Culture media listed may or may not meet the requirements of a regulated test method. It is the responsibility of the user to determine applicability in each situation. MICROBIOLOGY QUALITY CONTROL 208 Beverage Quality Control Application Selector Membranes Page Number LactobacillusDetection sp. Total BacteriaDetection Total ColiformsDetection Fecal ColiformsDetection Yeast Detectionand Mold GN-6 Metricel® MCE membrane disc filters, S-pack 213 • • • • • Metricel Black PES membrane disc filters, S-pack 214 • • • • Sentino™ Filter Dispenser 213a • • • • • Supor® 200 PES membrane disc filters, S-pack 215 • • Ampoule Media* HPC with TTC indicator broth 216 • M-FC broth 216 • MF-Endo broth 216 • M-Green YM broth 216 • M-TGE broth 216 • Orange Serum broth 216 • Trypticase Soy broth - USP 216 • application selector Filter Funnels 47 mm magnetic filter funnels 226 • • • • • Microcheck® II beverage monitors 227 • • • • • Sentino Magnetic filter funnels 225a • • • • • Vents Vacushield™ vent device 165 • • • • • Hardware and Accessories Filter funnel manifolds 229 • • • • • Filter funnel manifolds for MicroFunnel™ filter funnels 228 • • • • • Petri dishes 230, 280 • • • • • Sentino Microbiology Pump 224 • • • • • MICROBIOLOGY QUALITY CONTROL Stainless steel forceps 230, 280 • • • • • Vacuum/pressure pumps 279 • • • • • * Culture media listed may or may not meet the requirements of a regulated test method. It is the responsibility of the user to determine applicability in each situation. 1. 8 0 0 .5 2 1 . 1 5 2 0 ( U S A and Canada) (+)800.PALL.LIFE (Outside USA and Canada) www.pall.com/lab 209 Microbiology Quality Control Rapid, Reliable Results The accurate, reliable detection and identification of micro- organisms is critical to public safety and industrial economics. As we become more aware of the presence and variety of the organisms that share the world we live in, we realize the importance of knowing how to detect and control them. Pall is a leader in the development and manufacture of products to detect and control these microorganisms. Our products comply with international testing methods, are supported by technical literature, and carry certifications of quality. You can be confident that our affordable, easy-to-use products will meet the high quality standards you require. Membranes Culturing sensitive organisms can be difficult, and identification is critical for process control and public safety. Analysis membranes must be manufactured to the highest standards for accurate microbial growth and recovery. Pall’s mixed cellulose ester GN Metricel® membrane has set the standard worldwide for meeting stringent microbial regulations. Supor® Rely on Pall Life Sciences to simplify your microbiological analysis with our popular line of disposable MicroFunnel and Metricel Black membranes provide additional benefits filter funnels, quality hardware, and convenient accessories. that range from low drug and protein binding characteristics to background contrast for ease in counting colonies. Thoughtfully Designed Hardware These membranes provide uniform and consistent growth and Accessories of organisms. Pall offers a full line of microbiological ampoule media, MicroFunnel™ Disposable Filter Funnels laboratory hardware, and accessories like our Sentino™ Pall offers the widest selection of disposable filter funnels for Microbiology Pump, Sentino Filter Dispenser, Petri dishes, microbiological analysis, offering unique design features that and stainless steel forceps to simplify your microbial analysis give these products a reputation for quality and ease of use. procedures. application overview Industrial Microbiology Products MicroFunnel filter funnels make analysis easy. Design permits a simple squeeze separation of funnel from base to Ensuring the effectiveness of cleaning procedures, quality of access membrane. raw materials, and reliable processing capabilities are essential Funnels attach directly to standard laboratory manifolds, to preparing a safe, high quality end product. Pall’s 37 mm and volume graduations are clearly marked to make it easy Quality Monitor is used to monitor microelectronics water to measure your sample volume. quality to detect microorganism contamination that can block a sub-micron circuit path on a computer chip. The food and Each unit is individually bagged, gamma-irradiated, and beverage industry chooses the easy-to-use Microcheck™ II labeled for added assurance of lot traceability. beverage monitors to improve speed, productivity, and accuracy in the lab. MICROBIOLOGY QUALITY CONTROL 210 Responding to Contamination Control With Disposable Funnels The pharmaceutical microbiology market requires reliable and MicroFunnel Filter Funnels Demonstrate High accurate results as a basis for quality control of raw materials, Recovery of Test Organisms processes, and finished product. Critical decisions are made Test organism: daily and confidence in results, as well as methods to control Escherichia coli ATCC 11229 contamination during sampling and analysis, is a driving force % recovery % recovery in this market. A false positive on a test result can trigger a incubated in incubated by PN 4800 (GN-6 Metricel® base using removing to series of events that lead to unnecessary retesting, product membrane, 0.45 µm, TSB broth, MF-Endo broth, release delays, and extensive paperwork to document a white, gridded) 5 test units 5 test units course of action. This all leads to increased operating costs. Lot 1048L 98% 96% One way Pall Life Sciences has responded to contamination Lot 1382L 98% 94% control is by broadening our range of disposable filter funnels Lot 1878L 94% 98% with designs to help improve the sampling process. Whether the need is bioburden analysis, sterility testing, or water Test organism: Pseudomonas system monitoring, we have a MicroFunnel™ filter funnel aeruginosa ATCC 14207 to suit the application. Certified MicroFunnel disposable % recovery % recovery filter funnels are individually bagged, labeled, and ready incubated in incubated by to use. Each lot is evaluated for recovery performance. PN 4803 (Supor® base using removing to The standard selection of MicroFunnel filter funnels is ideal membrane, 0.2 µm, TSB broth, Pseudomonas white, gridded) 5 test units broth, 5 test units for any bioburden analysis. Lot 1305L 97% 91% application overview Lot 1443L 97% 97% Lot 1179M 96% 101% Test organism: Saccharomyces cerevisiae ATCC 4117 % recovery % recovery incubated in incubated by base using removing to PN 4805 (Metricel Black M-Green M-Green membrane, 0.45 µm, YM broth, YM broth, gridded) 5 test units 5 test units Lot 1197M 96% 101% Lot 1626M 100% 97% Lot 1933M 100% 103% MICROBIOLOGY QUALITY CONTROL MicroFunnel Plus filter funnels streamline QC testing. Simple, Versatile Contamination Control MicroFunnel Plus filter funnels are the only disposable filter funnels on the market that can serve as a sample cup and filter funnel in one product. This unique design further stream- lines sample collection
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