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Source: Globocan 2020

Number of new cases in 2020, both sexes, all ages Number of deaths in 2020, both sexes, all ages

Breast 2 261 419 1 796 144 Lung 2 206 771 Colorectum 935 173 Colorectum 1 931 590 830 180 Prostate 1 414 259 Stomach 768 793 Stomach 1 089 103 Breast 684 996 Liver 905 677 Oesophagus 544 076 Cervix uteri 604 127 Pancreas 466 003 Oesophagus 604 100 Prostate 375 304 Thyroid 586 202 Cervix uteri 341 831 Bladder 573 278 Leukaemia 311 594 Non-Hodgkin 544 352 Non- 259 793 Pancreas 495 773 Brain, 251 329 Leukaemia 474 519 Bladder 212 536 431 288 Ovary 207 252 Corpus uteri 417 367 Kidney 179 368 Lip, oral cavity 377 713 Lip, oral cavity 177 757 of skin 324 635 117 077 Ovary 313 959 99 840 Brain, central nervous system 308 102 Corpus uteri 97 370 Larynx 184 615 Gallbladder 84 695 Multiple myeloma 176 404 Nasopharynx 80 008 Nasopharynx 133 354 Melanoma of skin 57 043 Gallbladder 115 949 Oropharynx 48 143 Oropharynx 98 412 Thyroid 43 646 Hypopharynx 84 254 Hypopharynx 38 599 Hodgkin lymphoma 83 087 Mesothelioma 26 278 Testis 74 458 Hodgkin lymphoma 23 376 Salivary glands 53 583 Salivary glands 22 778 Vulva 45 240 Vulva 17 427 Penis 36 068 Kaposi 15 086 Kaposi sarcoma 34 270 Penis 13 211 Mesothelioma 30 870 Testis 9 334 Vagina 17 908 Vagina 7 995 0 500 000 1 000 000 1 500 000 2 000 000 0 500 000 1 000 000 1 500 000

Cancer incidence and mortality statistics worldwide and by region

Incidence Mortality Both sexes Males Females Both sexes Males Females Cum. risk Cum. risk Cum. risk Cum. risk Cum. risk Cum. risk New cases New cases New cases Deaths Deaths Deaths 0-74 (%) 0-74 (%) 0-74 (%) 0-74 (%) 0-74 (%) 0-74 (%) Eastern Africa 137 0.01 96 0.01 41 0.00 132 0.01 92 0.01 40 0.00 Middle Africa 57 0.01 44 0.01 13 0.00 56 0.01 43 0.01 13 0.00 Northern Africa 513 0.03 320 0.04 193 0.02 467 0.02 287 0.03 180 0.02 Southern Africa 296 0.07 203 0.12 93 0.03 270 0.07 181 0.13 89 0.03 Western Africa 116 0.01 102 0.02 14 0.00 113 0.01 99 0.02 14 0.00 Caribbean 31 0.01 25 0.01 6 0.00 28 0.01 24 0.01 4 0.00 Central America 389 0.03 254 0.04 135 0.02 351 0.02 232 0.04 119 0.01 South America 818 0.02 491 0.02 327 0.01 703 0.02 428 0.02 275 0.01 Northern America 4 119 0.05 3 083 0.08 1 036 0.03 3 119 0.04 2 388 0.05 731 0.02 Eastern Asia 5 815 0.02 3 863 0.03 1 952 0.02 4 918 0.02 3 341 0.03 1 577 0.01 South-Eastern Asia 782 0.01 438 0.01 344 0.01 687 0.01 393 0.01 294 0.01 South-Central Asia 1 972 0.01 1 041 0.01 931 0.01 1 772 0.01 920 0.01 852 0.01 Western Asia 1 166 0.06 677 0.07 489 0.05 947 0.05 587 0.06 360 0.04 Central and Eastern Europe 2 133 0.05 1 149 0.06 984 0.04 1 858 0.04 1 031 0.06 827 0.03 Western Europe 4 628 0.09 3 567 0.15 1 061 0.04 3 970 0.07 3 141 0.13 829 0.03 Southern Europe 2 941 0.09 2 159 0.14 782 0.04 2 596 0.07 1 912 0.11 684 0.03 Northern Europe 3 946 0.18 3 244 0.31 702 0.06 3 396 0.12 2 849 0.21 547 0.04 and New Zealand 1 000 0.14 799 0.22 201 0.06 886 0.11 729 0.17 157 0.05 Melanesia 11 0.02 5 0.02 6 0.02 9 0.01 4 0.01 5 0.01 Polynesia 0 0 0 0 0 0 0 0 0 0 0 0 Micronesia 0 0 0 0 0 0 0 0 0 0 0 0 Low HDI 318 0.01 255 0.01 63 0.00 306 0.01 245 0.01 61 0.00 Medium HDI 2 395 0.01 1 218 0.01 1 177 0.01 2 151 0.01 1 086 0.01 1 065 0.01 High HDI 5 606 0.02 3 335 0.02 2 271 0.01 4 902 0.02 2 997 0.02 1 905 0.01 Very high HDI 22 542 0.07 16 743 0.12 5 799 0.04 18 910 0.06 14 344 0.09 4 566 0.03 World 30 870 0.03 21 560 0.05 9 310 0.02 26 278 0.03 18 681 0.04 7 597 0.02

Incidence, both sexes Mortality, both sexes 5-year prevalence, both sexes

Africa Africa Africa (3.6%) (4%) (3.5%)

LAC** LAC** LAC** (4%) Europe (4.1%) Europe (4.2%) Europe (44.2%) (45%) (43.6%) N.America* N.America* N.America* (13.3%) (11.9%) (13.1%)

Asia Asia Asia (31.5%) (31.7%) (32.6%) Population Number Population Number Population Number Europe 13 648 Europe 11 820 Europe 16 135 Asia 9 735 Asia 8 324 Asia 12 090 *Northern America 4 119 *Northern America 3 119 *Northern America 4 850 **Latin America and the Caribbean 1 238 **Latin America and the Caribbean 1 082 **Latin America and the Caribbean 1 558 Africa 1 119 Africa 1 038 Africa 1 281 Oceania 1 011 Oceania 895 Oceania 1 133 Total 30 870 Total 26 278 Total 37 047

The Global Observatory - All Rights Reserved, December, 2020. Page 1 Age standardized (World) incidence rates, mesothelioma, males, all ages

≥ 0.79 0.27–0.79 0.13–0.27 0.07–0.13 Not applicable 0.0–0.07 No data

Age standardized (World) incidence rates, mesothelioma, females, all ages

≥ 0.24 0.12–0.24 0.04–0.12 0.0–0.04 Not applicable No data

Data source: GLOBOCAN 2020

Graph production: IARC (https://gco.iarc.fr/today) World Health Organization © International Agency for Research on Cancer 2020

Age standardized (World) incidence rates, mesothelioma, by sex Age standardized (World) incidence and mortality rates, mesothelioma

Males Females Incidence Mortality

Northern Europe 2.5 0.46 Northern Europe 1.4 1.1 Australia and New Zealand 2.2 0.57 Australia and New Zealand 1.3 1.1 Western Europe 1.3 0.35 Western Europe 0.79 0.65 Southern Europe 1.1 0.36 Southern Europe 0.70 0.58 Southern Africa 0.95 0.29 Southern Africa 0.55 0.51 Northern America 0.75 0.25 Western Asia 0.48 0.39 Western Asia 0.58 0.39 Northern America 0.47 0.33 Central and Eastern Europe 0.53 0.31 Central and Eastern Europe 0.41 0.32 World 0.46 0.17 World 0.30 0.25 Northern Africa 0.32 0.17 Northern Africa 0.24 0.22 Central America 0.31 0.14 Central America 0.21 0.19 Eastern Asia 0.28 0.14 Eastern Asia 0.20 0.16 South America 0.20 0.11 South America 0.15 0.13 Melanesia 0.16 0.14 Melanesia 0.14 0.12 South-Eastern Asia 0.13 0.09 South-Eastern Asia 0.11 0.09 Middle Africa 0.11 0.03 South-Central Asia 0.10 0.09 Western Africa 0.11 0.01 Middle Africa 0.07 0.06 South-Central Asia 0.11 0.10 Eastern Africa 0.06 0.06 Eastern Africa 0.09 0.03 Western Africa 0.06 0.06 Caribbean 0.08 0.02 Caribbean 0.05 0.04 Polynesia Polynesia Micronesia Micronesia

6.0 5.0 4.0 3.0 2.0 1.0 0 1.0 2.0 3.0 4.0 5.0 6.0 3.0 2.5 2.0 1.5 1.0 0.5 0 0.5 1.0 1.5 2.0 2.5 3.0 ASR (World) per 100 000 ASR (World) per 100 000

The Global Cancer Observatory - All Rights Reserved, December, 2020. Page 2