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Food Allergy in the United States: Report of the NIAID-Sponsored Expert Panel

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Food Allergy in the United States: Report of the NIAID-Sponsored Expert Panel Guidelines for the Diagnosis and Management of Food Allergy in the United States: Report of the NIAID-Sponsored Expert Panel Acknowledgments Primary Authors NIAID-Sponsored Expert Panel Authors Joshua A. Boyce, MD S. Hasan Arshad, MBBS, MRCP, DM, FRCP Division of Rheumatology, Immunology and Allergy School of Medicine Brigham and Women’s Hospital University of Southampton Department of Medicine Harvard Medical School Southampton, UK Boston, Mass The David Hide Asthma and Allergy Research Centre St Mary’s Hospital Amal Assa’ad, MD Newport, Isle of Wight, UK Division of Allergy and Immunology Southampton University Hospital NHS Trust Cincinnati Children’s Hospital Medical Center Southampton, UK University of Cincinnati Cincinnati, Ohio Sami L. Bahna, MD, DrPH A. Wesley Burks, MD Department of Pediatrics Division of Allergy and Immunology Section of Allergy and Immunology Department of Pediatrics Louisiana State University Health Sciences Center Duke University Medical Center Shreveport, La Durham, NC Lisa A. Beck, MD Stacie M. Jones, MD Department of Dermatology Division of Allergy and Immunology University of Rochester Medical Center Department of Pediatrics Rochester, NY University of Arkansas for Medical Sciences Arkansas Children’s Hospital Carol Byrd-Bredbenner, PhD, RD, FADA Little Rock, Ark Department of Nutritional Sciences Rutgers University Hugh A. Sampson, MD New Brunswick, NJ Elliot and Roslyn Jaffe Food Allergy Institute Division of Allergy and Immunology Carlos A. Camargo Jr, MD, DrPH Department of Pediatrics Department of Emergency Medicine Mount Sinai School of Medicine Division of Rheumatology, Allergy and Immunology New York, NY Department of Medicine Massachusetts General Hospital Robert A. Wood, MD Harvard Medical School Division of Allergy and Immunology Boston, Mass Department of Pediatrics The Johns Hopkins University School of Medicine Lawrence Eichenfield, MD Baltimore, Md Division of Pediatric and Adolescent Dermatology Rady Children’s Hospital Marshall Plaut, MD San Diego, Calif Division of Allergy, Immunology, and Transplantation Departments of Pediatrics and Medicine National Institute of Allergy and Infectious Diseases University of California, San Diego National Institutes of Health San Diego, Calif Bethesda, Md Glenn T. Furuta, MD Susan F. Cooper, MSc Section of Pediatric Gastroenterology, Hepatology, and Nutrition Division of Allergy, Immunology, and Transplantation Digestive Health Institute National Institute of Allergy and Infectious Diseases Children’s Hospital Denver National Institutes of Health Aurora, Colo Bethesda, Md Department of Pediatrics Matthew J. Fenton, PhD National Jewish Health Division of Allergy, Immunology, and Transplantation Denver, Colo National Institute of Allergy and Infectious Diseases Department of Pediatrics National Institutes of Health University of Colorado Denver School of Medicine Bethesda, Md Aurora, Colo S1 S2 BOYCE ET AL J ALLERGY CLIN IMMUNOL DECEMBER 2010 Jon M. Hanifin, MD Scripps Clinic Department of Dermatology San Diego, Calif Oregon Health and Science University F. Estelle R. Simons, MD Portland, Ore Departments of Pediatrics and Child Health and Immunology Carol Jones, RN, AE-C Faculty of Medicine Asthma Educator and Consultant University of Manitoba Allergy and Asthma Network Mother’s of Asthmatics Winnipeg, Manitoba, Canada McLean, Va Stephen J. Teach, MD, MPH Monica Kraft, MD Division of Emergency Medicine Division of Pulmonary, Allergy, and Critical Care Medicine Children’s National Medical Center Department of Medicine Washington, DC Duke University Medical Center Barbara P. Yawn, MD, MPH, MSc Durham, NC Department of Research Bruce D. Levy, MD Olmsted Medical Center Partners Asthma Center Rochester, Minn Pulmonary and Critical Medicine Department of Family and Community Health Brigham and Women’s Hospital and Harvard Medical School University of Minnesota School of Medicine Boston, Mass Minneapolis, Minn Phil Lieberman, MD Division of Allergy and Immunology Contributing Author Department of Medicine Julie M. Schwaninger, MSc University of Tennessee College of Medicine Division of Allergy, Immunology, and Transplantation Memphis, Tenn National Institute of Allergy and Infectious Diseases Stefano Luccioli, MD National Institutes of Health Office of Food Additive Safety Bethesda, Md US Food and Drug Administration College Park, Md Corresponding Author Kathleen M. McCall, BSN, RN Matthew J. Fenton, PhD Children’s Hospital of Orange County Division of Allergy, Immunology, and Transplantation Orange, Calif National Institute of Allergy and Infectious Diseases Lynda C. Schneider, MD National Institutes of Health Bethesda, Md Division of Immunology 6610 Rockledge Drive, Room 3105 Children’s Hospital Boston Bethesda, Md 20892 Boston, Mass Phone: 301-496-8973 Ronald A. Simon, MD Fax: 301-402-0175 Division of Allergy, Asthma and Immunology E-mail: [email protected] Sources of funding Publication of this article was supported by the Food Allergy Initiative. Disclosure of potential conflict of interest: J. A. Boyce has served on the Advisory Board of GlaxoSmithKline. He has served as a consultant and/or speaker for Altana, GlaxoSmithKline, and Merck. He has received funding/ grant support from the National Institutes of Health. A. Assa’ad holds, or is listed as an inventor on, US patent application #10/566903, entitled ‘‘Geneticmarkers of food allergy.’’She has served as a consultant for GlaxoSmithKline and as a speaker for the American College of Allergy, Asthma, and Immunology, the North East Allergy Society, the Virginia Allergy Society, the New England Allergy Society, and the American Academy of Pediatrics. Dr Assa’ad has received funding/grant support from GlaxoSmithKline. A. W. Burks holds, or is listed as an inventor on, multiple US patents related to food allergy. He owns stock in Allertein and MastCell, Inc, and is a minority stockholder in Dannon Co Probiotics. He has served as a consultant for ActoGeniX NV, McNeil Nutritionals, Mead Johnson, and Novartis. He has served on the speaker’s bureau for EpiPen/Dey, LP, and has served on the data monitoring committee for Genentech. He has served on an expert panel for Nutricia. Dr Burks has received funding/grant support from the Food Allergy and Anaphylaxis Network, Gerber, Mead Johnson, and the National Institutes of Health. S. M. Jones has served as a speaker and grant reviewer and has served on the medical advisory committee for the Food Allergy and Anaphylaxis Network. She has received funding/grant support from Dyax Corp, the Food Allergy and Anaphylaxis Network, Mead Johnson, the National Peanut Board, and the National Institutes of Health. H. A. Sampson holds, or is listed as an inventor on, multiple US patents related to food allergy. He owns stock in Allertein Therapeutics. He is the immediate past president of the American Academy of Allergy, Asthma, and Immunology. He has served as a consultant for Allertein Therapeutics, the American Academy of Allergy, Asthma, and Immunology, the Food Allergy Initiative, and Schering Plough. He has received funding/grant support for research projects from the Food Allergy Initiative, the National Institutes of Health (Division of Receipt and Referral, National Institute of Allergy and Infectious Diseases, National Center for Complementary and Alternative Medicine), and Phadia AB. He is a co- owner of Herbal Spring, LLC. R. A. Wood has served as a speaker/advisory board member for GlaxoSmithKline, Merck, and Dey. He has received funding/grant support from Genentech and the National Institutes of Health (National Institute of Allergy and Infectious Diseases). S. H. Arshad has received funding/grant support from the National Institutes of Health and the National Institute of Health Research, UK. S. L. Bahna has received funding/grant support from Genentech. L. A. Beck has received funding/grant support from the American Academy of Allergy, Asthma, and Immunology, the National Eczema Association, and the National Institutes of Health. J ALLERGY CLIN IMMUNOL BOYCE ET AL S3 VOLUME 126, NUMBER 6 C. Byrd-Bredbenner owns stock in Johnson & Johnson. She has received funding/grant support from the US Department of Agriculture, the Canned Food Alliance, and the New Jersey Department of Health and Senior Services. C. A. Camargo Jr has consulted for Dey and Novartis. He has received funding/grant support from a variety of government agencies and not-for-profit research foundations, as well as Dey and Novartis. L. Eichenfield has received funding/grant support from a variety of not-for-profit foundations, as well as Astellas, Ferndale, Johnson & Johnson, Novartis, Sinclair, Stiefel, and Therapeutics Inc. G. T. Furuta has served as a consultant and/or speaker to Ception Therapeutics and TAP. He has received funding/grant support from the American Gastrointestinal Association and the National Institutes of Health. J. M. Hanifin has served as served as a consultant for ALZA, Anesiva, Inc, Barrier Therapeutics, Inc, Milliken & Company, Nordic Biotech, Novartis Pharmaceuticals Corporation, Shionogi USA, Taisho Pharmaceutical R&D, Inc, Teikoku Pharma USA, Inc, UCB, York Pharma, ZARS, Inc, and ZymoGenetics. He has served as an investigator or received research funding from ALZA, Astellas Pharma US, Inc, Asubio Pharmaceuticals, Inc, Centocor, Inc, Corgentech, Novartis, Nucryst Pharmaceuticals, Seattle Genetics, and Shionogi USA. M. Kraft has served as a consultant and/or speaker for Astra-Zeneca, Genentech, GlaxoSmithKline, Merck, Novartis, and Sepracor. She has received funding/grant
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