Artistic Swimming
Total Page:16
File Type:pdf, Size:1020Kb
Load more
Recommended publications
-
Plant Responses to Abiotic Stresses and Rhizobacterial Biostimulants: Metabolomics and Epigenetics Perspectives
H OH metabolites OH Review Plant Responses to Abiotic Stresses and Rhizobacterial Biostimulants: Metabolomics and Epigenetics Perspectives Motseoa M. Lephatsi 1 , Vanessa Meyer 2 , Lizelle A. Piater 1 , Ian A. Dubery 1 and Fidele Tugizimana 1,3,* 1 Department of Biochemistry, University of Johannesburg, Auckland Park, Johannesburg 2006, South Africa; [email protected] (M.M.L.); [email protected] (L.A.P.); [email protected] (I.A.D.) 2 School of Molecular and Cell Biology, University of the Witwatersrand, Private Bag 3, WITS, Johannesburg 2050, South Africa; [email protected] 3 International Research and Development Division, Omnia Group, Ltd., Johannesburg 2021, South Africa * Correspondence: [email protected]; Tel.: +27-011-559-7784 Abstract: In response to abiotic stresses, plants mount comprehensive stress-specific responses which mediate signal transduction cascades, transcription of relevant responsive genes and the accumulation of numerous different stress-specific transcripts and metabolites, as well as coordinated stress-specific biochemical and physiological readjustments. These natural mechanisms employed by plants are however not always sufficient to ensure plant survival under abiotic stress conditions. Biostimulants such as plant growth-promoting rhizobacteria (PGPR) formulation are emerging as novel strategies for improving crop quality, yield and resilience against adverse environmental conditions. However, to successfully formulate these microbial-based biostimulants and design efficient application programs, the understanding of molecular and physiological mechanisms that govern biostimulant-plant interactions is imperatively required. Systems biology approaches, such as Citation: Lephatsi, M.M.; Meyer, V.; metabolomics, can unravel insights on the complex network of plant-PGPR interactions allowing for Piater, L.A.; Dubery, I.A.; Tugizimana, the identification of molecular targets responsible for improved growth and crop quality. -
Men Final Entries
Final Entries - Athletes List by event European Athletics Indoor Championships 2021, Torun/POL Tot. Number of countries Tot. Number of athletes Tot. Number of Men Tot. Number of Women 47 733 405 328 FINAL ENTRIES - Men 60m Senior Men Num. of countries: 33 Num. of athletes: 71 Member Federation Surname First Name DoB PB SB ARM Donigian Alexander 20/10/1993 6.64i 6.79i ART Keletela Dorian Celeste 06/02/1999 6.79i 6.85i AUT Fuchs Markus 14/11/1995 6.62i 6.69i BEL Kuba Di-Vita Gaylord 17/11/1995 6.73i 6.75i BEL Vleminckx Kobe 31/05/1998 6.65i 6.65i BLR Bliznets Dzianis 12/03/1995 6.75i 6.75i BLR Bohdan Maksim 19/03/1997 6.77i 6.77i BLR Zabalotny Yury 24/02/1997 6.72i 6.72i BUL Dimitrov Denis 10/02/1994 6.65i 6.73i BUL Jivkov Vesselin 26/01/2001 6.76i 6.80i CZE Hampl Štěpán 10/11/1999 6.70i 6.70i CZE Stromšík Zdeněk 25/11/1994 6.60i 6.68i CZE Veleba Jan 06/12/1986 6.65i 6.65i DEN Hansen Simon 30/06/1998 6.75i 6.75i DEN Kjær Emil Mader 20/12/1999 6.77i 6.77i DEN Musah Kojo 15/04/1996 6.61i 6.61i ESP López Sergio 05/07/1999 6.67i 6.74i ESP Rodríguez Daniel 26/01/1995 6.67i 6.67i ESP Sanchez Ricardo 10/08/1999 6.75i 6.75i EST Nazarov Karl Erik 17/03/1999 6.63i 6.63i FIN Illukka Riku 21/09/1999 6.73i 6.73i FIN Purola Samuel 19/05/2000 6.67i 6.67i FIN Samuelsson Samuli 23/06/1995 6.66i 6.66i FRA Fall Mouhamadou 25/02/1992 6.62i 6.62i FRA Golitin Amaury 28/01/1997 6.62i 6.62i GBR Aikines-Aryeetey Harry 29/08/1988 6.55i 6.67i GBR Bromby Oliver 30/03/1998 6.63i 6.65i GBR Robertson Andrew 17/12/1990 6.54i 6.61i GER Corucle Philipp 18/07/1997 6.62i -
Distinct Types of Short Open Reading Frames Are Translated in Plant Cells
Downloaded from genome.cshlp.org on September 30, 2021 - Published by Cold Spring Harbor Laboratory Press 1 Distinct types of short open reading frames are translated in 2 plant cells 3 4 Igor Fesenko1,*, Ilya Kirov2, Andrey Kniazev1, Regina Khazigaleeva1, Vassili Lazarev3,4, Daria 5 Kharlampieva3, Ekaterina Grafskaia3,4, Viktor Zgoda5, Ivan Butenko3, Georgy Arapidi1,3, Anna 6 Mamaeva1, Vadim Ivanov1, Vadim Govorun3. 7 1Laboratory of functional genomics and plant proteomics, Shemyakin and Ovchinnikov Institute of 8 Bioorganic Chemistry, Moscow, Russian Federation; 2Laboratory of marker-assisted and genomic 9 selection of plants, All-Russian Research Institute of Agricultural Biotechnology, Moscow, Russian 10 Federation; 3 Research Institute for Physico-Chemical Medicine, Moscow, Russian Federation; 4Moscow 11 Institute of Physics and Technology, Dolgoprudny, Moscow region, Russia; 5Laboratory of System 12 Biology, Institute of Biomedical Chemistry, Moscow, Russian Federation. 13 14 Corresponding author(s). 15 * Igor Fesenko, e-mail: [email protected] 16 17 Running title: Translation of sORFs in moss 18 19 Keywords: short open reading frames, plant peptides, LC-MS/MS, evolution, alternative splicing, 20 lncRNA 21 22 ABSTRACT 23 Genomes contain millions of short (<100 codons) open reading frames (sORFs), which are usually 24 dismissed during gene annotation. Nevertheless, peptides encoded by such sORFs can play important 25 biological roles, and their impact on cellular processes has long been underestimated. Here, we 1 Downloaded from genome.cshlp.org on September 30, 2021 - Published by Cold Spring Harbor Laboratory Press 26 analyzed approximately 70,000 transcribed sORFs in the model plant Physcomitrella patens (moss). 27 Several distinct classes of sORFs that differ in terms of their position on transcripts and the level of 28 evolutionary conservation are present in the moss genome. -
ESC Guidelines for the Diagnosis and Management of Atrial Fibrillation
European Heart Journal (2020) 00,1À126 ESC GUIDELINES doi:10.1093/eurheartj/ehaa612 2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in Downloaded from https://academic.oup.com/eurheartj/advance-article/doi/10.1093/eurheartj/ehaa612/5899003 by guest on 31 August 2020 collaboration with the European Association of Cardio-Thoracic Surgery (EACTS) The Task Force for the diagnosis and management of atrial fibrillation of the European Society of Cardiology (ESC) Developed with the special contribution of the European Heart Rhythm Association (EHRA) of the ESC Authors/Task Force Members: Gerhard Hindricks* (Chairperson) (Germany), Tatjana Potpara* (Chairperson) (Serbia), Nikolaos Dagres (Germany), Elena Arbelo (Spain), Jeroen J. Bax (Netherlands), Carina Blomstro¨m-Lundqvist (Sweden), Giuseppe Boriani (Italy), Manuel Castella1 (Spain), Gheorghe-Andrei Dan (Romania), Polychronis E. Dilaveris (Greece), Laurent Fauchier (France), Gerasimos Filippatos (Greece), Jonathan M. Kalman (Australia), Mark La Meir1 * Corresponding authors: The two chairpersons contributed equally to the document. Gerhard Hindricks, University Clinic of Cardiology, Heart Center Leipzig, Department of Cardiology and Electrophysiology, Leipzig Heart Institute, Stru¨mpellstr. 39, 04289 Leipzig, Germany. Tel: þ49 34 1865 1410, Fax: þ49 34 1865 1460, Email: [email protected] Tatjana Potpara, School of Medicine, Belgrade University, dr Subotica 8, 11000 Belgrade, Serbia, and Cardiology Clinic, Clinical Centre of Serbia, -
16Th FINA World Masters Championships 2015 KAZAN (RUS)
16th FINA World Masters Championships 2015 KAZAN (RUS) 800 m Freestyle Men Results RANK SURNAME & NAME FED BORN 50 m 100 m 200 m 300 m 400 m 500 m 600 m 700 m FINAL TEAM CAT AGE GROUP 85-89 QUALIFYING STANDARD: 23:13.00 CR : 15:16.96 WR : 14:37.00 1 SKOBELEV Boris RUS 1930 57.07 2:04.20 4:21.07 6:40.73 8:59.42 11:19.63 13:41.02 16:02.54 18:20.43 Russian Reserve 85-89 1:07.13 2:16.87 2:19.66 2:18.69 2:20.21 2:21.39 2:21.52 2:17.89 2 COUTTIE Peter AUS 1930 1:10.96 2:34.81 5:22.83 8:08.13 10:53.13 13:37.70 16:20.90 19:02.42 21:41.08 Malvern Marlins 85-89 1:23.85 2:48.02 2:45.30 2:45.00 2:44.57 2:43.20 2:41.52 2:38.66 AGE GROUP 80-84 QUALIFYING STANDARD: 20:40.00 CR : 13:28.82 WR : 11:49.00 1 VERESHAGINE Anry RUS 1934 43.97 1:30.97 3:10.65 4:51.02 6:33.13 8:15.05 9:57.37 11:39.31 13:15.13 CR All Stars 80-84 47.00 1:39.68 1:40.37 1:42.11 1:41.92 1:42.32 1:41.94 1:35.82 2 BROVIN Igor RUS 1932 44.99 1:36.71 3:26.25 5:15.64 7:07.53 8:58.81 10:53.14 12:52.05 14:39.25 Sprut 80-84 51.72 1:49.54 1:49.39 1:51.89 1:51.28 1:54.33 1:58.91 1:47.20 3 MULLINS Steve USA 1932 56.13 2:04.19 4:18.97 6:35.14 8:50.62 11:04.23 13:18.27 15:29.71 17:32.64 Illinois Masters 80-84 1:08.06 2:14.78 2:16.17 2:15.48 2:13.61 2:14.04 2:11.44 2:02.93 4 KAMAL Ahmed Fouad EGY 1933 54.26 2:00.61 4:23.06 6:43.94 9:06.08 11:27.77 13:45.86 16:04.98 18:07.97 Gezira Sporting Club 80-84 1:06.35 2:22.45 2:20.88 2:22.14 2:21.69 2:18.09 2:19.12 2:02.99 NOT CLASSIFIED 0 HOLE Gerhard GER 1935 80-84 Ssf Bonn 05 DNS AGE GROUP 75-79 QUALIFYING STANDARD: 18:50.00 CR : 11:25.95 WR : 11:08.00 -
The SH-SY5Y Cell Line in Parkinson's Disease Research
Xicoy et al. Molecular Neurodegeneration (2017) 12:10 DOI 10.1186/s13024-017-0149-0 REVIEW Open Access The SH-SY5Y cell line in Parkinson’s disease research: a systematic review Helena Xicoy1,2, Bé Wieringa1 and Gerard J.M. Martens2* Abstract Parkinson’s disease (PD) is a devastating and highly prevalent neurodegenerative disease for which only symptomatic treatment is available. In order to develop a truly effective disease-modifying therapy, improvement of our current understanding of the molecular and cellular mechanisms underlying PD pathogenesis and progression is crucial. For this purpose, standardization of research protocols and disease models is necessary. As human dopaminergic neurons, the cells mainly affected in PD, are difficult to obtain and maintain as primary cells, current PD research is mostly performed with permanently established neuronal cell models, in particular the neuroblastoma SH-SY5Y lineage. This cell line is frequently chosen because of its human origin, catecholaminergic (though not strictly dopaminergic) neuronal properties, and ease of maintenance. However, there is no consensus on many fundamental aspects that are associated with its use, such as the effects of culture media composition and of variations in differentiation protocols. Here we present the outcome of a systematic review of scientific articles that have used SH-SY5Y cells to explore PD. We describe the cell source, culture conditions, differentiation protocols, methods/approaches used to mimic PD and the preclinical validation of the SH-SY5Y findings by employing alternative cellular and animal models. Thus, this overview may help to standardize the use of the SH-SY5Y cell line in PD research and serve as a future user’sguide. -
Muslims in Spain, 1492–1814 Mediterranean Reconfigurations Intercultural Trade, Commercial Litigation, and Legal Pluralism
Muslims in Spain, 1492– 1814 Mediterranean Reconfigurations Intercultural Trade, Commercial Litigation, and Legal Pluralism Series Editors Wolfgang Kaiser (Université Paris I, Panthéon- Sorbonne) Guillaume Calafat (Université Paris I, Panthéon- Sorbonne) volume 3 The titles published in this series are listed at brill.com/ cmed Muslims in Spain, 1492– 1814 Living and Negotiating in the Land of the Infidel By Eloy Martín Corrales Translated by Consuelo López- Morillas LEIDEN | BOSTON This is an open access title distributed under the terms of the CC BY-NC 4.0 license, which permits any non-commercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. Further information and the complete license text can be found at https://creativecommons.org/licenses/by-nc/4.0/ The terms of the CC license apply only to the original material. The use of material from other sources (indicated by a reference) such as diagrams, illustrations, photos and text samples may require further permission from the respective copyright holder. Cover illustration: “El embajador de Marruecos” (Catalog Number: G002789) Museo del Prado. Library of Congress Cataloging-in-Publication Data Names: Martín Corrales, E. (Eloy), author. | Lopez-Morillas, Consuelo, translator. Title: Muslims in Spain, 1492-1814 : living and negotiating in the land of the infidel / by Eloy Martín-Corrales ; translated by Consuelo López-Morillas. Description: Leiden ; Boston : Brill, [2021] | Series: Mediterranean reconfigurations ; volume 3 | Original title unknown. | Includes bibliographical references and index. Identifiers: LCCN 2020046144 (print) | LCCN 2020046145 (ebook) | ISBN 9789004381476 (hardback) | ISBN 9789004443761 (ebook) Subjects: LCSH: Muslims—Spain—History. | Spain—Ethnic relations—History. -
Conselleria De Sanitat Consellería De Sanidad
Conselleria de Sanitat Consellería de Sanidad Notificació de liquidacions per taxes sanitàries en Notificación de liquidaciones por tasas sanitarias en l’Hospital General de Castelló. Liquidació número el Hospital General de Castellón. Liquidación número 0466705600514 i altres. [2014/517] 0466705600514 y otras. [2014/517] Segons que disposa l’article 112 de la Llei 58/2003, de 17 de De conformidad con lo dispuesto en el artículo 112 de la Ley desembre, General Tributària, i com que s’ha intentat la notificació a la 58/2003, de 17 de diciembre, General Tributaria, y habiéndose intenta- persona interessada o al seu representant per dues vegades, sense que do la notificación al interesado o su representante por dos veces, sin que haja sigut possible per causes no imputables al centre gestor, es posa haya sido posible practicarlas por causas no imputables al centro gestor, de manifest, mitjançant este anunci, que estan pendents de notificar les se pone de manifiesto, mediante el presente anuncio, que se encuentran liquidacions per taxes sanitàries que s’especifiquen a continuació. pendientes de notificar las liquidaciones por tasas sanitarias cuyo inte- resado se especifica a continuación. Per tot això, dispose que els subjectes passius, obligats tributaris En virtud de lo anterior dispongo que los sujetos pasivos, obligados indicats anteriorment, o els seus representants ben acreditats, hauran de tributarios indicados anteriormente, o sus representantes debidamente comparéixer en el termini de 15 dies naturals, comptadors des de l’ende- acreditados, deberán comparecer en el plazo de 15 días naturales, con- mà de la publicació d’esta resolució en el Diari Oficial de la Comunitat tados desde el siguiente al de la publicación de la presente resolución Valenciana, de dilluns a divendres, en l’horari de 09.00 a 14.00 hores, en el Diari Oficial de la Generalitat Valenciana, de lunes a viernes, en en el centre gestor Hospital de Castelló (av. -
Human Genetics and Clinical Aspects of Neurodevelopmental Disorders
bioRxiv preprint doi: https://doi.org/10.1101/000687; this version posted October 6, 2014. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY 4.0 International license. Human genetics and clinical aspects of neurodevelopmental disorders Gholson J. Lyon1,2,3,*, Jason O’Rawe1,3 1Stanley Institute for Cognitive Genomics, One Bungtown Road, Cold Spring Harbor Laboratory, NY, USA, 11724 2Institute for Genomic Medicine, Utah Foundation for Biomedical Research, E 3300 S, Salt Lake City, Salt Lake City, UT, USA, 84106 3Stony Brook University, 100 Nicolls Rd, Stony Brook, NY, USA, 11794 * Corresponding author: Gholson J. Lyon Email: [email protected] Other author emails: Jason O'Rawe: [email protected] 1 bioRxiv preprint doi: https://doi.org/10.1101/000687; this version posted October 6, 2014. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY 4.0 International license. Introduction “our incomplete studies do not permit actual classification; but it is better to leave things by themselves rather than to force them into classes which have their foundation only on paper” – Edouard Seguin (Seguin, 1866) “The fundamental mistake which vitiates all work based upon Mendel’s method is the neglect of ancestry, and the attempt to regard the whole effect upon off- spring, produced by a particular parent, as due to the existence in the parent of particular structural characters; while the contradictory results obtained by those who have observed the offspring of parents apparently identical in cer- tain characters show clearly enough that not only the parents themselves, but their race, that is their ancestry, must be taken into account before the result of pairing them can be predicted” – Walter Frank Raphael Weldon (Weldon, 1902). -
The Critical Role of Histone Methylation in Tumour Progression and As Anti-Cancer Targets in Neuroblastoma
The critical role of histone methylation in tumour progression and as anti-cancer targets in neuroblastoma Matthew Wong A thesis in fulfilment of the requirements for the degree of Doctor of Philosophy Supervisor: Dr Tao Liu Co-supervisor: A. Prof Patsie Polly School of Women’s and Children’s Health Faculty of Medicine February 2016 PLEASE TYPE THE UNIVERSITY OF NEW SOUTH WALES Thesis/Dissertation Sheet Surname or Family name: First name: Matthew Other name/s: Kwok Kei Wong Abbreviation for degree as given in the University calendar: PhD School: School of Women’s and Children’s Heath Faculty: Faculty of Medicine Title: The critical role of histone methylation in tumour progression and as anti-cancer targets in neuroblastoma N-Myc induces neuroblastoma by regulating the expression of target oncogenes. Histone H3 lysine 79 (H3K79) methylation at Myc-responsive elements of target gene promoters is a strict prerequisites for Myc-induced transcriptional activation. DOT1L is the only known histone methyltransferase that catalyses mono-methylation (me), di- methylation (me2) and tri-methylation (me3) at the histone H3K79 position, which have been linked to gene transcriptional activation. JMJD6 is a bi-functional arginine demethylase and lysyl-hydroxylase. The JMJD6 gene is located on the chromosome 17q25 position. 17q21-gter gain has been identified as the most frequent chromosome alternation in neuroblastoma and an indicator of poor patient prognostic. Here, I investigated the roles of DOT1L and JMJD6 in N-Myc over-expressing neuroblastoma. I found that N-Myc up-regulated DOT1L mRNA and protein expression, by binding to an E-box at the DOT1L gene promoter. -
2020 ESC Guidelin Es for the Management of Acute Coronary Syndromes in Patients Presenting Without Persistent ST-Segment Elevation
1 2020 ESC Guidelin es for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation The Task Force for the management of acute coronary syndromes in patients presenting without persistent ST-seg- ment elevation of the European Society of Cardiology (ESC) ESC Guidelines ESC Guidelines Authors/Task Force Members: Jean-Philippe Collet* (Chairperson) [AQ7](France), Holger Thiele* (Chairperson) (Germany), Emanuele Barbato (Italy), Olivier Barthélémy (France), Johann Bauersachs (Germany), Deepak L. Bhatt (USA), Paul Dendale (Belgium), Maria Dorobantu (Romania), Thor Edvardsen (Norway), Thierry Folliguet (France), Chris P. Gale (UK), Martine Gilard (France), Alexander Jobs (Germany), Peter Jüni (Canada), Ekaterini Lambrinou (Cyprus), Basil S. Lewis (Israel), Julinda Mehilli (Germany), Emanuele Meliga (Italy), Béla Merkely (Hungary), Christian Mueller (Switzerland), Marco Roffi (Switzerland), Frans H. Rutten (Netherlands), Dirk Sibbing (Germany), George C.M. Siontis (Switzerland) Document Reviewers: Adnan Kastrati (CPG Review Coordinator) (Germany), Mamas A. Mamas (CPG Review Coordinator) (UK), Victor Aboyans (France), Dominick J. Angiolillo (USA), Hector Bueno (Spain), Raffaele Bugiardini (Italy), Robert A. Byrne (Ireland), Silvia Castelletti (Italy), Alaide Chieffo (Italy), Veronique Cornelissen (Belgium), Filippo Crea (Italy), Victoria Delgado (Netherlands), Heinz Drexel (Austria), Marek Gierlotka (Poland), Sigrun Halvorsen (Norway), Kristina Hermann Haugaa (Norway), Ewa A. Jankowska (Poland), Hugo A. Katus (Germany), Tim Kinnaird (UK), Jolanda Kluin (Netherlands), Vijay Kunadian (UK), Ulf Landmesser (Germany), Christophe Leclercq (France), Maddalena Lettino (Italy), Leena Meinila (Finland), Darren My- lotte (Ireland), Gjin Ndrepepa (Germany), Elmir Omerovic (Sweden), Roberto F. E. Pedretti (Ita- ly), Steffen E. Petersen (UK), Anna Sonia Petronio (Italy), Gianluca Pontone (Italy), Bogdan A. Popescu (Romania), Tatjana Potpara (Serbia), Kausik K. -
A Foundation for the Future
A FOUNDATION FOR THE FUTURE INVESTORS REPORT 2012–13 NORTHWESTERN UNIVERSITY Dear alumni and friends, As much as this is an Investors Report, it is also living proof that a passion for collaboration continues to define the Kellogg community. Your collective support has powered the forward movement of our ambitious strategic plan, fueled development of our cutting-edge curriculum, enabled our global thought leadership, and helped us attract the highest caliber of students and faculty—all key to solidifying our reputation among the world’s elite business schools. This year, you also helped set a new record for alumni support of Kellogg. Our applications and admissions numbers are up dramatically. We have outpaced our peer schools in career placements for new graduates. And we have broken ground on our new global hub. Your unwavering commitment to everything that Kellogg stands for helps make all that possible. Your continuing support keeps us on our trajectory to transform business education and practice to meet the challenges of the new economy. Thank you for investing in Kellogg today and securing the future for generations of courageous leaders to come. All the best, Sally Blount ’92, Dean 4 KELLOGG.NORTHWESTERN.EDU/INVEST contentS 6 Transforming Together 8 Early Investors 10 Kellogg Leadership Circle 13 Kellogg Investors Leaders Partners Innovators Activators Catalysts who gave $1,000 to $2,499 who gave up to $1,000 99 Corporate Affiliates 101 Kellogg Investors by Class Year 1929 1949 1962 1975 1988 2001 1934 1950 1963 1976 1989 2002