DOCSLIB.ORG

Kate Fitzgerald

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Kate Fitzgerald In This Issue: 2019 Young Investigator Awardees pgs. 3-8 Italian COVID-19 Storms pg. 11 In Memorium pgs. 12-15 New Member Mini-Bios pgs. 17-19 Spotlight: Women in Science pgs. 21-23 Cytokines 2020 pgs. 24-27 Si g n THE INTERNATIONALa CYTOKINEl & INTERFERONs SOCIETY+­­­ NEWSLETTER APRIL 2020 I VOLUME 8 I NO. 1 A NOTE FROM THE ICIS PRESIDENT Kate Fitzgerald I write this note as all of us reach a new norm of working “remotely”. I want to extend my sincere appreciation to all members of the ICIS community around the globe who have stepped up to meet the unique and unforeseen challenges of this time. The precautions that have been implemented at all of our institutions and companies, in accordance with local and national public health guidance, will no doubt help mitigate the spread of COVID-19. We should remain firmly committed to physical distancing to make us all safer. We stand with our Italian, Spanish and New York colleagues in particular, who are facing very difficult times right now and hope things will improve there soon. It’s hard to understate the importance of the scientific enterprise and the work we as cytokine and interferon biologists do in light of the COVID-19 pandemic. Our past and current efforts to understand the host response to viruses and other pathogens and the importance of IFN and cytokines in controlling infection and the immune response to vaccines could not be more important than it is now. Understanding cytokine and interferon biology is fundamental to human health and disease. We hope the knowledge gained from all our efforts can be put to good use to stem the threat of Sars-CoV2. Beyond the current threat, it is also clear that cytokines and interferons function in disease initiation, development and progression allowing cytokine targeted therapies to come online for the benefit of patients afflicted with a myriad of infectious, inflammatory, autoimmune diseases as well as cancer. Cytokine and interferon biology continue to attract scientists including immunologists as well as those from numerous other research disciplines. As a society we serve as a forum to bring together all those interested in cytokine and IFN biology to advance human health. It is an honor and a pleasure to serve as the President of the ICIS for the next 2 years. I want to thank Nancy Reich for her service as President for the past two years and for guiding my transition into this role. I am excited to build on Nancy’s work as well as that of the past society presidents, David Wallach, Charles Samuel, Luke O’Neill, Richard Flavell and Tadatsugu Taniguchi who collectively established a strong foundation for this wonderful society. I also want to thank Christopher Hunter, President-Elect who has already been an active and willing participant in all of my efforts thus far. We are both so grateful for Joan Oefner, managing director of the society who we were fortunate to work with when we co-chaired the Boston meeting in 2018. Joan is phenomenal. She brings her energy, enthusiasm and drive to all that she does. I am particularly grateful for her ability to think 5 steps ahead and always see the bigger picture. To those of you who serve on all of our committees, I thank you for your service. I hope that as a team we can all build on the success of past leadership and enhance the impact of the society in the coming years. continued on pg 2 Future Cytokines 2021, Newsletter Editors: Meetings October 17 - 20, 2021 Howard Young Cardiff, Wales, UK Marta Catalfamo Cytokines 2020, Cytokines 2022, Di Yu / Zhian Chen November 1-4, 2020 September 20 - 23, 2022 Seattle, USA Big Island, Hawaii USA Managing Director: Joan Oefner The International Cytokine & Interferon Society Headquarters: [email protected] • TEL: 1-800-947-1960 • FAX: 1-201-322-1818 • www.cytokinesociety.org continued from pg 1 A major goal of the society is to broaden our reach internationally by encouraging our international colleagues to join the society and contribute to society efforts. In the coming years we have enlisted meeting organizers out to 2024 to hold our annual meeting across the globe. Next fall (fingers crossed) our annual meeting will be held in Seattle, Washington. Michael Gale, Ram Saven and colleagues have put together a spectacular program. Further, 2021, plans are well underway for Cardiff with Simon Jones leading the effort and future meetings being planned for Hawaii, Greece and Korea. I want to especially thank Brendan Jenkins who has done an outstanding job lining up meeting organizers and guiding meeting planning efforts. Brendan has kindly agreed to a second term leading the meetings committee which is a huge benefit to the society. The society will provide all the logistical needs of organizing future meetings through Joan Oefner and our agreement with MCI. This includes the meeting website, registration, coordination of hotels, convention centers, etc. This will free meeting organizers to focus on the scientific program. I encourage members to step-up and reach out to Brendan to discuss organizing future meetings. I also want to highlight our commitment as a society to diversity and in particular gender balance. It is important that meeting organizers, scientific programs and society committees are balanced both in terms of gender and geographical diversity. There is no shortage of outstanding colleagues across the globe that should be included on our rosters of meeting speakers and committees. I encourage any of you interested in participating on one of our committees and serving the society to reach out to me or Joan. I also want to alert our society members about our commitment to providing a family friendly environment at our annual meetings. Starting in Seattle, we will be providing complimentary childcare support to allow our fellow scientists with young children the opportunity to attend our meetings and social events. The final night Networking Dinner will also be family friendly at the Seattle Aquarium, a venue sure to delight all generations! It has always been the aim of the ICIS to keep dues low and make membership affordable for scientists at all levels, from graduate students to Full Professors. We strive to keep our management costs down so the Society can remain viable for many years to come. We also strive to raise funds to support travel awards allowing scientists from across the globe especially those from developing countries to attend our annual meetings. We are incredibly grateful for the generosity of the Milstein family who have supported our society for more than 30 years with the Milstein Awards. The coming years will be challenging for the society however, as support from the Milstein family is ending this year. We are so grateful for their support for the last 30 years and will be working hard to identify alternative donors who can support our annual awards and travel awards which we will continue to include in the meeting budgets. In this regard, the society has established a new Development committee jointly led by Simon Jones and Eleanor Fish, to help leverage our collective contacts to fill this void. In closing, I want to thank you for being a member of the ICIS and supporting our field. As a society, we have a lot to do. We will continue to voice your concerns, advocate for scientific research, advance the training of students and post-doctoral fellows, and sustain the progress of our field in this era of breathtaking opportunity. I look forward to seeing you all at our next annual meeting in Seattle where the program promises to not disappoint. With warmest regards to everyone, stay safe during these difficult times and be well. Kate SCIENCEQUOTES “ Anybody who has been seriously engaged in scientific work of any kind realizes that over the entrance to the “gates of the temple of science are written the words:” ‘Ye must have faith.’” Max Planck 2 APRIL 2020 I VOLUME 8 I NO. 1 I THE INTERNATIONAL CYTOKINE & INTERFERON SOCIETY NEWSLETTER I [email protected] I TEL: 1-800-947-1960 I FAX: 1-201-322-1818 I www.cytokinesociety.org 2019 THE MILSTEIN YOUNG INVESTIGATOR AWARDEES Every year up to five awards are granted to individuals who have made notable contributions to either basic or clinical research. This award is provided by a generous gift of the Milstein Family. JUAN FUXMAN SARAH DOYLE, BASS, Ph.D. Ph.D. Assistant Professor of Biology Assistant Professor in Immunology Boston University, Boston, USA Dept. Clinical Medicine, School of Medicine, JF Coordinator for BSc in Human Health and Disease, Dr. Fuxman Bass is an Assistant Professor in the Biology TBSI, Head of Immunobiology Research Group, Trinity Department at Boston University. His overarching scientific goals College Institute of Neuroscience (TCIN), Trinity are to elucidate the underlying principles governing cytokine regulation. In particular, his lab focuses on delineating the College Dublin, Dublin, Ireland gene regulatory networks involved in cytokine transcription and identifying novel transcription factors involved in this process by Dr. Doyle’s research lab is focused on the impact of signalling integrating multiple omics approaches. In addition, his lab studies downstream of the innate immune Toll/IL-1 Receptor (TIR)-super the role of virally-encoded transcription factors in modulating family in the maintenance of tissue homeostasis and the initiation gene expression as a mechanism of viral immune evasion. His of pathology. This family recognizes and responds to host derived work has been funded by the Pew Charitable Trusts and by the danger signals and includes the IL-1 family cytokine receptors National Institutes of Health through the K99/R00, R35, and U01 IL-1R and IL-18R.
Load more

Recommended publications
  • Living Being's Finished Arrangement of DNA
    e in G net ts ic n E e n g m i e n c e e n r a i v n d g A ISSN: 2169-0111 Advancements in Genetic Engineering Editorial Living Being's Finished Arrangement of DNA Bahman Hosseini* Department of Horticulture, Faculty of Agriculture, Urmia University, Iran INTRODUCTION MS2 coat protein work, deciding the total nucleotide-succession of bacteriophage MS2-RNA (whose genome encodes only four Genomics is an interdisciplinary field of science zeroing in on qualities in 3569 base sets [bp]) and Simian infection 40 out of the construction, work, advancement, planning, and altering of 1976 and 1978, individually. genomes. A genome is a living being's finished arrangement of DNA, including the entirety of its qualities. Rather than Notwithstanding his fundamental work on the amino corrosive hereditary qualities, which alludes to the investigation of arrangement of insulin, Frederick Sanger and his associates individual qualities and their parts in legacy, genomics focuses assumed a vital part in the advancement of DNA sequencing on the aggregate portrayal and evaluation of the entirety of a life strategies that empowered the foundation of thorough genome form's qualities, their interrelations and effect on the creature. sequencing projects. In 1975, he and Alan Coulson distributed a Qualities may coordinate the creation of proteins with the help sequencing methodology utilizing DNA polymerase with of chemicals and courier atoms. Thusly, proteins make up body radiolabelled nucleotides that he called the Plus and Minus designs, for example, organs and tissues just as control synthetic strategy. This elaborate two firmly related strategies that created responses and convey signals between cells.
    [Show full text]
  • Cytokines MONTRÉAL 2008
    Cytokines MONTRÉAL 2008 Translating Science into Health: Cytokines in Cancer, Infl ammation and Infectious Diseases 7th Joint Conference of the International Cytokine Society and the International Society for Interferon and Cytokine Research Photo: Tourisme Montréal Photo: Tourisme October 12-16, 2008 Fairmont Queen Elizabeth Hotel Montreal Quebec CANADA Cytokines Montreal 2008 1 PROGRAM From cell separation to molecular analysis The Gold Standard in Cell Isolation • Separation of functional, cytokine-secreting cells • Virtually any cell type from any species • Superior viability, purity and recovery Cytokines and Growth Factors • New, broad portfolio: human - mouse - rat • Excellent purity and activity • Optimized for cell culture applications MACSmolecular Tools for Molecular Analysis • Tools for signal transduction • State of the art microRNA analysis • Comprehensive gene expression profiling Unless otherwise specifically indicated, Miltenyi Biotec products and services are for research use only and not for therapeutic or diagnostic use. Miltenyi Biotec Inc. Phone 800 FOR MACS www.miltenyibiotec.com 12740 Earhart Avenue +1 530 888 8871 [email protected] Auburn CA 95602, USA Fax +1 530 888 8925 2 Cytokines Montreal 2008 ContentsWelcome to Montreal ..................................................................................... 4-5 Sponsors and Exhibitors ................................................................................... 6 Conference Venue ...........................................................................................
    [Show full text]
  • Beyond Vaccines: Promising Therapeutics for COVID-19 and Emerging Viruses
    Research Canada speaks to Dr. Eleanor Fish, a scientific advisor to Canada’s COVID- 19 Therapeutics Task Force Beyond Vaccines: Promising Therapeutics for COVID-19 and Emerging Viruses The federal government’s COVID-19 Therapeutics Task Force provides advice on the best and most promising treatments for COVID-19 procurement, whether these are still in development and merit support, including via applications to the federal Strategic Innovation Fund, or are existing medications. The Task Force also makes recommendations on therapies developed for a different use that may have an application to COVID-19. Dr. Eleanor Fish is among 11 science advisors to the Therapeutics Task Force. A Professor of Immunology at the University of Toronto and a Senior Scientist at University Health Network, she investigates the behaviour of cytokines, which play a role in cell-to-cell communication during the body’s immune response. In a recent Research Canada interview with Ms. Deborah Gordon-El- Bihbety, President and CEO, Dr. Fish talked about the critical place of therapeutics in the battle against COVID-19, and their important role in preparing for the diseases and epidemics to come. "Vaccines are a very important tool in our toolbox against COVID-19, but they are not a complete solution." - Dr. Eleanor Fish 1 RESEARCH CANADA: Canada’s vaccination campaign is under way, and we’ve been told that all Canadians who want a vaccine will have it by next fall. What role do therapeutics play, separate from vaccines, in the fight against COVID-19? DR. ELEANOR FISH: Vaccines are a very important tool in our toolbox against COVID-19, but they are not a complete solution.
    [Show full text]
  • ISICR Vol. 15.1
    ISICR Officers President Eleanor Fish President-elect INTERNATIONAL SOCIETY FOR Leonidas Platanias INTERFERON AND CYTOKINE RESEARCH Secretary April 2008 Tom Hamilton Volume 15, No. 1 Treasurer Bob Friedman Executive Director A Message from the new ISICR Cliff Brownstein President, Eleanor Fish It is with gratitude and humility that I assume the Future ISICR Meetings responsibilities of incoming President of the ISICR. I am honored to have been elected by my peers and am fortunate to have in place a Board of 2008 Meeting Directors and Committee members that are as Joint ISICR/ICS committed to strengthening our Society as I am. In Montreal, Canada recent months, to ensure that our Society reflects Oct. 12-16 the scientific activities of junior investigators, as positions have www.cytokines2008.org become vacant on the various ISICR Committees, in consultation 2009 Meeting with the Committee Chairs I have made best efforts to invite the par- Joint ISICR/ICS/SLB ticipation of younger investigators who share our vision of a strong, Lisbon, Portugal international, collegial Society. I invite members to participate in your Society - just contact me to let me know of your interest. 2010 Meeting Joint ISICR/ICS Within recent years we have seen a revival of interest in the Chicago, Illinois pleiotropic activities of interferons, touching on many different bio- logical disciplines. Moreover, the role of cytokines and how they ISICR WWW Site inform us of biological processes in normal and diseased states is an www.ISICR.org ever expanding field. I would like to focus my tenure as President on a number of key areas: ISICR Business Office O Communication.
    [Show full text]
  • Dec 08 News Vol 15 No 3 Final.Qxp
    ISICR Officers President Eleanor Fish President-elect Leonidas Platanias Secretary Tom Hamilton December 2008 - Volume 15, No. 3 Treasurer Bob Friedman Executive Director One on one: An Interview with Cliff Brownstein Giorgio Trinchieri, Recipient of the 2008 Milstein Award Future ISICR Meetings Thomas Tan 2009 Meeting Giorgio Trinchieri received his medical degree Joint ISICR/ICS/SLB from the University of Torino, Italy, in 1973. He Lisbon, Portugal was a member of the Basel Institute for Immunology (Basel, Switzerland) and an investi- 2010 Meeting gator at the Swiss Institute for Experimental Joint ISICR/ICS Cancer Research (Epalanges sur Lausanne, Chicago, Illinois Switzerland). From 1979 to 1999 he was at Wistar Institute in Philadelphia and became Hilary Koprowski Professor and Chairman of the Immunology Program; he ISICR WWW Site was also Wistar Professor of Medicine at the University of www.ISICR.org Pennsylvania. He then served as director of the Schering Plough Laboratory for Immunological Research in Dardilly, France, and an ISICR Business Office NIH Fogarty Scholar at the Laboratory for Parasitic Diseases, [email protected] NIAID, before becoming director of the Cancer and Inflammation TEL: 301-634-7250 Program (CIP) and Chief of the Laboratory of Experimental FAX: 301-634-7420 Immunology at NCI in August 2006. As CIP director, he oversees the operations of two major NCI intramural laboratories, the Laboratory ISICR Newsletter Editors of Experimental Immunology and the Laboratory of Molecular Howard Young Immunoregulation. These two laboratories constitute the major [email protected] immunologic component of the inflammation and cancer initiative, Fax: 301-846-1673 which spans the NCI's campuses in Frederick and Bethesda and seeks Hannah Nguyen to partner NCI's expertise in inflammation and immunology with its cutting-edge cancer etiology and carcinogenesis program.
    [Show full text]
  • Genome Mapping and Genomics in Animals Volume 1
    Genome Mapping and Genomics in Animals Volume 1 Series Editor: Chittaranjan Kole Wayne Hunter, Chittaranjan Kole (Editors) Genome Mapping and Genomics in Arthropods With 25 Illustrations, 3 in Color 123 Way n e Hu n t e r Chittaranjan Kole USDA, ARS, United States Department of Genetics & Biochemistry Horticultural Research Laboratory Clemson University 2001 South Rock Road Clemson, SC 29634 Fort Pierce, FL 34945 USA USA e-mail: [email protected] e-mail: [email protected] ISBN 978-3-540-73832-9 e-ISBN 978-3-540-73833-6 DOI 10.1007/978-3-540-73833-6 Library of Congress Control Number: 2007934674 © Springer-Verlag Berlin Heidelberg 2008 This work is subject to copyright. All rights are reserved, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broad- casting, reproduction on microfilm or in any other way, and storage in data banks. Duplication of this publication or parts thereof is permitted only under the provisions of the German Copyright Law of September 9, 1965, in its current version, and permissions for use must always be obtained from Springer. Violations are liable for prosecution under the German Copyright Law. The use of general descriptive names, registered names, trademarks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. Cover design: WMXDesign GmbH, Heidelberg, Germany Printed on acid-free paper 987654321 springer.com Preface to the Series The deciphering of the sequence of a gene for the first time, the gene for bacterio- phage MS2 coat protein to be specific, by Walter Fiers and his coworkers in 1972 marked the beginning of a new era in genetics, popularly known as the genomics era.
    [Show full text]
  • Clark, Kyle.Pdf
    SEQUENCING FIELD ISOLATES OF ILTV by Kyle Clark A thesis submitted to the Faculty of the University of Delaware in partial fulfillment of the requirements for the degree of Bachelor of Science in Animal Science with Distinction. Spring 2010 Copyright 2010 Kyle Clark All Rights Reserved Sequencing Field Isolates of ILTV by Kyle Clark Approved: ________________________________________________ Calvin Keeler, Ph.D. Professor in charge of thesis on behalf of the Advisory Committee Approved: ________________________________________________ Carl Schmidt, Ph.D. Committee member from the Department of Animal and Food Sciences Approved:_________________________________________________ Nicole Donofrio, Ph.D. Committee member from the Board of Senior Thesis Readers Approved:__________________________________________________ Ismat Shah, Ph.D. Chair of the University Committee on Student and Faculty Honors ACKNOWLEDGMENTS I would like to thank Bruce Kingham for his support and sequencing assistance. I would also like to thank Cynthea Boettger for her continued assistance and instruction throughout my research. Finally, I wish to thank the University of Delaware Undergraduate Research office for their grant to further support my research. iii TABLE OF CONTENTS LIST OF TABLES ......................................................................................................... vi LIST OF FIGURES ...................................................................................................... vii ABSTRACT ...............................................................................................................
    [Show full text]
  • Human Genetics 1990–2009
    Portfolio Review Human Genetics 1990–2009 June 2010 Acknowledgements The Wellcome Trust would like to thank the many people who generously gave up their time to participate in this review. The project was led by Liz Allen, Michael Dunn and Claire Vaughan. Key input and support was provided by Dave Carr, Kevin Dolby, Audrey Duncanson, Katherine Littler, Suzi Morris, Annie Sanderson and Jo Scott (landscaping analysis), and Lois Reynolds and Tilli Tansey (Wellcome Trust Expert Group). We also would like to thank David Lynn for his ongoing support to the review. The views expressed in this report are those of the Wellcome Trust project team – drawing on the evidence compiled during the review. We are indebted to the independent Expert Group, who were pivotal in providing the assessments of the Wellcome Trust’s role in supporting human genetics and have informed ‘our’ speculations for the future. Finally, we would like to thank Professor Francis Collins, who provided valuable input to the development of the timelines. The Wellcome Trust is a charity registered in England and Wales, no. 210183. Contents Acknowledgements 2 Overview and key findings 4 Landmarks in human genetics 6 1. Introduction and background 8 2. Human genetics research: the global research landscape 9 2.1 Human genetics publication output: 1989–2008 10 3. Looking back: the Wellcome Trust and human genetics 14 3.1 Building research capacity and infrastructure 14 3.1.1 Wellcome Trust Sanger Institute (WTSI) 15 3.1.2 Wellcome Trust Centre for Human Genetics 15 3.1.3 Collaborations, consortia and partnerships 16 3.1.4 Research resources and data 16 3.2 Advancing knowledge and making discoveries 17 3.3 Advancing knowledge and making discoveries: within the field of human genetics 18 3.4 Advancing knowledge and making discoveries: beyond the field of human genetics – ‘ripple’ effects 19 Case studies 22 4.
    [Show full text]
  • CMAJ WHO Enters New Terrain in Ebola Research
    CMAJ News WHO enters new terrain in Ebola research he meeting on unproven inter- ventions for Ebola at the World T Health Organization on Sept. 4 and 5 takes the global agency into “absolutely uncharted territory,” says WHO spokesperson, Dr. Margaret Harris. “We’re actually often criticized for being incredibly slow about saying, ‘Do this over that’, because we demand enormous levels of evidence,” she says. But for Ebola virus disease, there are no approved therapies, so WHO is attempting to move investigational interventions forward, including medi- cations, vaccines and so-called conva- lescent serum, made from the blood of survivors. The Sept. 4 meeting, aimed at guid- ing research in the midst of the out- NikiLitov/iStock/Thinkstock break, marks a sharp turn for WHO, In the absence of approved therapies for patients diagnosed with Ebola, WHO is taking where research efforts are viewed as the unprecedented step of attempting to move research forward. fragmented. About five years ago, WHO eliminated its office of research break at 78%, and in late August the three control animals died. Five of the strategy; the department leading the disease spread to another country — seven people treated with ZMapp have Ebola research effort, known as Senegal — and another city — Port survived, but it is unclear if the medica- Knowledge, Ethics and Research, was Harcourt, Nigeria, the hub of Nigeria’s tion helped them to recover and it will only formed at the end of 2013. But the oil and gas industry, where Canadian be months before there is more ZMapp Ebola crisis forced a change.
    [Show full text]
  • Keynote Speakers
    Keynote Speakers Dr. Katie Flanagan, BA(Hons) MBBS DTM&H MA PhD CCST FRCP FRACP, leads the Infectious Diseases Service at Launceston General Hospital in Tasmania, and is a clinical Associate Professor at the University of Tasmania, Australia. She obtained a degree in Physiological Sciences from Oxford University, followed by her MBBS from the University of London. She is a UK and Australia accredited Infectious Diseases Physician. Katie obtained her PhD in malaria immunology based at Oxford University. She was previously Head of Infant Immunology Research at the MRC Laboratories in The Gambia from 2005-11. Dr. Thumbi Ndung’u, BVM, PhD, is the Scientific Director of the HIV Pathogenesis Programme at the University of KwaZulu Natal in South Africa. He is a virologist with a PhD from Harvard University, Boston, USA. His main research interests are in host-virus interactions and immune responses in HIV-1 infection. He is also interested in the development of biomedical interventions that can be used in resource-limited settings to prevent or treat HIV/AIDS. He is an Associate Professor in HIV/AIDS Research at the the Doris Duke Medical Research Institute, Nelson R Mandela School of Medicine, University of KwaZulu-Natal. He holds the South African Department of Science and Technology/National Research Foundation (DST/NRF) Research Chair in Systems Biology of HIV/AIDS. Dr. Josef Penninger BA, MD, PhD, is Scientific Director of the Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna, Austria. He is Professor in the Departments of Immunology and Medical Biophysics at the University of Toronto, Canada, Professor of Genetics, University of Vienna, Austria, Honorary Professor of Peking Union Medical College/Chinese Academy of Medical Sciences, Beijing, China, Affiliate Scientist, Keenan Research Centre, Li Ka Shing Knowledge Institute of St.
    [Show full text]
  • The Dynamic Changes in Cytokine Responses in COVID-19
    meeting report SARS-COV-2 The dynamic changes in cytokine responses in COVID-19: a snapshot of the current state of knowledge “The role of cytokines in COVID-19” online symposium was presented on 18 June 2020 by the NIH/FDA Immunology and Cytokine Interest Groups and was purposed to discuss our rapidly changing understanding of COVID-19-related cytokine responses in diferent stages of infection, including the etiologies, downstream consequences and possible mitigation strategies. The recording is available at https://nci.rev.vbrick.com/ sharevideo/03106730-66cc-47ba-870b-f6e6274a998a. he symposium was opened by address that underscored the broad variety serum cytokine concentrations with disease Anthony Fauci, Director of the of clinical presentations of COVID-19, outcome. Her data showed that IL-6, IL-8 TNational Institute of Allergy and thus highlighting the central role of the and TNF, and to a lesser extent, IL-1β, were Infectious Diseases at the US National immune response in this disease. She also elevated at the time of hospitalization, and Institutes of Health (NIAID, NIH), and remarked on the apparent geographic their concentrations correlated with disease Janet Woodcock, Director of the Center clusters of disease manifestations and the outcome and mortality, even after correcting of Drug Evaluation and Research, Food need to better understand possible factors for age, ethnicity, race and comorbidities, and Drug Administration (CDER, FDA) in host–pathogen interactions beyond those suggesting that they could be used to and currently leading the therapeutics health conditions already identified, such identify patients at risk of severe disease2. component of Operation Warp Speed.
    [Show full text]
  • December 2012
    Department of Immunology Newsletter image provided by Michael Corrin VOL I – ISSUE 4 December 2012 Message from the Chair, UPCOMING SEMINARS Dr. Juan Carlos Zúñiga-Pflücker EASTON SEMINARS – Another year, another spectacular Immunology Holiday Party for January 2013 which we have Alessandra Ferzoco, Elisa Porfilio and many IGSA Room 2172 MSB at 11:10 a.m. members to thank. Jennifer Gommerman’s Mayan inspired January 14, 2013 apocalyptic monologue was terrific, and terrifying if we really had Richard M. Ransohoff, MD to choose whom to save. For those that could not make it, I am “Monocytes and microglia: Where they sorry, you missed a wonderful evening, but here is a recap of some come from and what they do.” (Host: Dr. Eleanor Fish) key items: the Richard Miller award was given to Janet Markle (Danska lab) and the Bernhard Cinader award by was given to January 21, 2013 Peter Chen (Carlyle lab); the Examiner of the Year award went to Jorge Kalil, MD, PhD “From molecular immunopathogenesis Michele Anderson, with Alberto Martin as a close runner-up. Our to the development of a vaccine to avoid department’s long-running holiday party DJ, Ernie West, was a post infectious human autoimmune recognized for his many years of service, and James Carlyle won disease.” (Host: Dr. Michelle Letarte) the newly minted “Lord of the dance” gold record award. The centerpiece competition winners were from the Kelly MacDonald January 28, 2013 lab, and the Zúñiga-Pflücker lab as runner-ups. The new fashion- Jeremy Mogridge, PhD show competition award was won by Catherine Schrankel (Rast “Detection of danger by the Nlrp1b inflammasome.” lab).
    [Show full text]