Clinical Profile and Incidence of Infection in Systemic Lupus Erythematosus Patients at Medical Inpatient Installation, Department of Internal Medicine, Dr
49 Majalah Biomorfologi Volume 31 Number 2, July 2021 p-ISSN: 0215-8833, e-ISSN: 2716-0920, DOI: 10.20473/mbiom.v31i2.2021.49-56 Clinical profile and incidence of infection in Systemic Lupus Erythematosus patients at Medical Inpatient Installation, Department of Internal Medicine, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia in 2016 Desy Trilistyoati1, Betty Agustina2*, Awalia3 1Faculty of Medicine, Universitas Airlangga, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. 2Department of Clinical Pathology, Faculty of Medicine, Universitas Airlangga; Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. 3Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga; Dr. Soetomo General Academic Hospital; Siloam Hospital, Surabaya, Indonesia. Article Info ABSTRACT Article history: Background: Systemic Lupus Erythematosus (SLE) is an Received Sep 20, 2020 autoimmune disease with unknown aetiology. SLE attacks multiple Revised Mar 3, 2021 organs with diverse clinical manifestations. Most patients get immunosuppressant therapy that suppresses immune system, Accepted Mar 24, 2021 Published Jul 1, 2021 causing the body to be susceptible to infection. Objective: to describe clinical manifestations, laboratory abnormalities, and incidence of infections in SLE patients hospitalized at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia in 2016. Keywords: Disease Materials and Methods: Cross-sectional descriptive observational Medicine study used medical records of 273 SLE patients hospitalized at Dr. Systemic Lupus Soetomo General Academic Hospital, Surabaya, Indonesia in 2016. Erythematosus Results: Clinical manifestations found in this study were malar rash Lupus nephritis 7.33%, discoid rash 2.93%, oral ulcer 8.42%, allopecia 16.48%, Infection arthritis 26.74%, serositis 13.19%, kidney 35.9%, neurology Autoimmune disease 24.91%, anemia 73.71%, leucopenia 32.67%, lymphopenia 76.89%, Immunosuppressant and thrombocytopenia 33.86%.
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