Chapter 6 Mucokinetics and Surfactants
Total Page:16
File Type:pdf, Size:1020Kb
Load more
Recommended publications
-
Appendix a Common Abbreviations Used in Medication
UNIVERSITY OF AMSTERDAM MASTERS THESIS Impact of Medication Grouping on Fall Risk Prediction in Elders: A Retrospective Analysis of MIMIC-III Critical Care Database Student: SRP Mentor: Noman Dormosh Dr. Martijn C. Schut Student No. 11412682 – SRP Tutor: Prof. dr. Ameen Abu-Hanna SRP Address: Amsterdam University Medical Center - Location AMC Department Medical Informatics Meibergdreef 9, 1105 AZ Amsterdam Practice teaching period: November 2018 - June 2019 A thesis submitted in fulfillment of the requirements for the degree of Master of Medical Informatics iii Abstract Background: Falls are the leading cause of injury in elderly patients. Risk factors for falls in- cluding among others history of falls, old age, and female gender. Research studies have also linked certain medications with an increased risk of fall in what is called fall-risk-increasing drugs (FRIDs), such as psychotropics and cardiovascular drugs. However, there is a lack of consistency in the definitions of FRIDs between the studies and many studies did not use any systematic classification for medications. Objective: The aim of this study was to investigate the effect of grouping medications at different levels of granularity of a medication classification system on the performance of fall risk prediction models. Methods: This is a retrospective analysis of the MIMIC-III cohort database. We created seven prediction models including demographic, comorbidity and medication variables. Medica- tions were grouped using the anatomical therapeutic chemical classification system (ATC) starting from the most specific scope of medications and moving up to the more generic groups: one model used individual medications (ATC level 5), four models used medication grouping at levels one, two, three and four of the ATC and one model did not include med- ications. -
Central Valley Toxicology Drug List
Chloroform ~F~ Lithium ~A~ Chlorpheniramine Loratadine Famotidine Acebutolol Chlorpromazine Lorazepam Fenoprofen Acetaminophen Cimetidine Loxapine Fentanyl Acetone Citalopram LSD (Lysergide) Fexofenadine 6-mono- Clomipramine acetylmorphine Flecainide ~M~ Clonazepam a-Hydroxyalprazolam Fluconazole Maprotiline Clonidine a-Hydroxytriazolam Flunitrazepam MDA Clorazepate Albuterol Fluoxetine MDMA Clozapine Alprazolam Fluphenazine Medazepam Cocaethylene Amantadine Flurazepam Meperidine Cocaine 7-Aminoflunitrazepam Fluvoxamine Mephobarbital Codeine Amiodarone Fosinopril Meprobamate Conine Amitriptyline Furosemide Mesoridazine Cotinine Amlodipine Methadone Cyanide ~G~ Amobarbital Methanol Cyclobenzaprine Gabapentin Amoxapine d-Methamphetamine Cyclosporine GHB d-Amphetamine l-Methamphetamine Glutethamide l-Amphetamine ~D~ Methapyrilene Guaifenesin Aprobarbital Demoxepam Methaqualone Atenolol Desalkylfurazepam ~H~ Methocarbamol Atropine Desipramine Halazepam Methylphenidate ~B~ Desmethyldoxepin Haloperidol Methyprylon Dextromethoraphan Heroin Metoclopramide Baclofen Diazepam Hexobarbital Metoprolol Barbital Digoxin Hydrocodone Mexiletine Benzoylecgonine Dihydrocodein Hydromorphone Midazolam Benzphetamine Dihydrokevain Hydroxychloroquine Mirtazapine Benztropine Diltiazem Hydroxyzine Morphine (Total/Free) Brodificoum Dimenhydrinate Bromazepam ~N~ Diphenhydramine ~I~ Bupivacaine Nafcillin Disopyramide Ibuprofen Buprenorphine Naloxone Doxapram Imipramine Bupropion Naltrexone Doxazosin Indomethacin Buspirone NAPA Doxepin Isoniazid Butabarbital Naproxen -
The New Face of Drug Abuse: Impact on Your Children, Family, and Community
The New Face of Drug Abuse: Impact on your Children, Family, and Community Patrick J. Sammon, Ph.D . [email protected] Impact of Prescription Drug Abuse: Illegal use of these drugs is responsible for multiple overdoses and fatalities Opiate addiction is blamed for causing a surge in crime: Robberies and break-ins at pharmacies Drug shoppers scamming doctors Harassments, assaults, and robberies of patients leaving drugstores Shoplifting and burglaries to support addiction Domestic violence and abuse Who’s at risk, who are the most vulnerable?: Adolescents - Sharp increase in 12 to 17 yr. olds and the 18 to 25 yr. olds Women - Increase rate of use in younger women Older adults - 17% of 60 + yr. olds may be affected by prescription drug abuse Why are Prescription Drugs so Popular? Legal, Easy to Obtain, Cheap and Safe & Non-addictive Legal: Perception that there is less legal risk than illicit drugs − Federal law does not distinguish between CI & CII drugs Easily obtainable: - From users, diverters, clinics, hospitals, Emergency Departments and practitioners and easy to steal Cheap: Low or no co-pay cost; may motivate people to use or sell PD’s Safer and Non-addictive: - Easily identity and less stigma than street drugs - Higher purity and less risky - Less HIV or hepatitis risk - Easier to use, no IV injecting but what about tolerance…and addiction! Commonly Misused and Abused Prescription & OTC Drugs Substance misuse is use of a drug that varies from a socially or medically accepted use. Substance abuse - any use of drugs that cause physical, psychological, economic, legal or social harm to the individual user or to others affected by the drug use's behavior. -
)&F1y3x PHARMACEUTICAL APPENDIX to THE
)&f1y3X PHARMACEUTICAL APPENDIX TO THE HARMONIZED TARIFF SCHEDULE )&f1y3X PHARMACEUTICAL APPENDIX TO THE TARIFF SCHEDULE 3 Table 1. This table enumerates products described by International Non-proprietary Names (INN) which shall be entered free of duty under general note 13 to the tariff schedule. The Chemical Abstracts Service (CAS) registry numbers also set forth in this table are included to assist in the identification of the products concerned. For purposes of the tariff schedule, any references to a product enumerated in this table includes such product by whatever name known. Product CAS No. Product CAS No. ABAMECTIN 65195-55-3 ACTODIGIN 36983-69-4 ABANOQUIL 90402-40-7 ADAFENOXATE 82168-26-1 ABCIXIMAB 143653-53-6 ADAMEXINE 54785-02-3 ABECARNIL 111841-85-1 ADAPALENE 106685-40-9 ABITESARTAN 137882-98-5 ADAPROLOL 101479-70-3 ABLUKAST 96566-25-5 ADATANSERIN 127266-56-2 ABUNIDAZOLE 91017-58-2 ADEFOVIR 106941-25-7 ACADESINE 2627-69-2 ADELMIDROL 1675-66-7 ACAMPROSATE 77337-76-9 ADEMETIONINE 17176-17-9 ACAPRAZINE 55485-20-6 ADENOSINE PHOSPHATE 61-19-8 ACARBOSE 56180-94-0 ADIBENDAN 100510-33-6 ACEBROCHOL 514-50-1 ADICILLIN 525-94-0 ACEBURIC ACID 26976-72-7 ADIMOLOL 78459-19-5 ACEBUTOLOL 37517-30-9 ADINAZOLAM 37115-32-5 ACECAINIDE 32795-44-1 ADIPHENINE 64-95-9 ACECARBROMAL 77-66-7 ADIPIODONE 606-17-7 ACECLIDINE 827-61-2 ADITEREN 56066-19-4 ACECLOFENAC 89796-99-6 ADITOPRIM 56066-63-8 ACEDAPSONE 77-46-3 ADOSOPINE 88124-26-9 ACEDIASULFONE SODIUM 127-60-6 ADOZELESIN 110314-48-2 ACEDOBEN 556-08-1 ADRAFINIL 63547-13-7 ACEFLURANOL 80595-73-9 ADRENALONE -
Injectable Anesthesia in South American Camelids
INJECTABLE ANESTHESIA IN SOUTH AMERICAN CAMELIDS Thomas Riebold DVM, Diplomate ACVAA Veterinary Teaching Hospital College of Veterinary Medicine Oregon State University Corvallis, Oregon 97331 INTRODUCTION Interest in llamas, and more recently in alpacas, as pets and as breeding and pack animals has led to increased demand for veterinary services for them. While they have some unique species characteristics regarding anesthesia, many of the principles and techniques used in food animal and equine anesthesia also apply to South American camelids. Except for differences in size, anesthetic management of alpacas and llamas is similar. Much like there are species differences between cattle, sheep, and goats in their response to xylazine, it does appear that alpacas require higher doses of sedatives, approximately 10-20%, to obtain the same response that lower doses of sedatives would obtain in llamas. PREANESTHETIC CONSIDERATIONS Consideration for preanesthetic preparation includes fasting, assessment of hematologic and blood chemistry values, venous catheterization, and estimation of bodyweight. The camelid has a stomach divided into three compartments. Therefore, potential complications similar to those of domestic ruminants, regurgitation and aspiration pneumonia, exist during anesthesia. Abdominal tympany as it occurs in anesthetized domestic ruminants does not appear to occur in anesthetized camelids. It is recommended that the animals be fasted 12-18 hours and deprived of water for 8-12 hours. In nonelective cases, this is often not possible and precautions should be taken to avoid aspiration of gastric fluid and ingesta. Fasting neonatal camelids is not advisable because hypoglycemia may result. As in other species, hematologic and blood chemistry values are determined before anesthesia. -
“Opioid” Definition Drug Inclusion and Exclusion List
WSHA WSMA Opioid Prescribing Report Medication Inclusion/Exclusion list For purposes of developing WSHA WSMA Opioid Prescribing Report metrics, the following medications tracked in the Prescription Monitoring Program database were included and counted as “opioid prescriptions”: Drug Name ACETAMINOPHEN-CODEINE ASCOMP WITH CODEINE BELLADONNA-OPIUM BUTALB-ACETAMINOPH-CAFF-CODEIN BUTALB-CAFF-ACETAMINOPH-CODEIN BUTALBITAL COMPOUND-CODEINE BUTORPHANOL TARTRATE CARISOPRODOL-ASPIRIN-CODEINE CHERATUSSIN AC CHERATUSSIN DAC CODEINE SULFATE CODEINE-GUAIFENESIN DEMEROL DILAUDID DOLOPHINE HCL DURAMORPH ENDOCET FENTANYL CITRATE FENTORA FIORICET WITH CODEINE FIORINAL WITH CODEINE #3 GUAIATUSSIN AC GUAIFENESIN AC GUAIFENESIN DAC GUAIFENESIN W/CODEINE GUAIFENESIN-CODEINE HYDROCODONE BITARTRATE HYDROCODONE BT-HOMATROPINE MBR HYDROCODONE-ACETAMINOPHEN HYDROCODONE-CHLORPHENIRAMNE ER HYDROCODONE-HOMATROPINE MBR HYDROCODONE-IBUPROFEN HYDROMET HYDROMORPHONE HCL INFUMORPH IOPHEN-C NR LAZANDA LEVORPHANOL TARTRATE LORTAB MEPERIDINE HCL MORPHINE SULFATE NORCO NUCYNTA OPANA OPIUM TINCTURE OXAYDO OXYCODONE HCL OXYCODONE HCL-ASPIRIN OXYCODONE HCL-IBUPROFEN OXYCODONE HYDROCHLORIDE OXYCODONE-ACETAMINOPHEN OXYMORPHONE HCL PENTAZOCINE-NALOXONE HCL PERCOCET PRIMLEV PROMETHAZINE VC-CODEINE PROMETHAZINE-CODEINE PROMETHAZINE-PHENYLEPH-CODEINE ROXICODONE SUBSYS SUFENTANIL CITRATE TRAMADOL HCL TRAMADOL HCL-ACETAMINOPHEN TUSSIGON TUSSIONEX TYLENOL-CODEINE NO.3 TYLENOL-CODEINE NO.4 ULTRACET ULTRAM VICODIN VICODIN ES VICODIN HP VIRTUSSIN AC Other medications, used primarily to -
Use of Antitussives After the Initiation of Angiotensin-Converting Enzyme Inhibitors
저작자표시-비영리-변경금지 2.0 대한민국 이용자는 아래의 조건을 따르는 경우에 한하여 자유롭게 l 이 저작물을 복제, 배포, 전송, 전시, 공연 및 방송할 수 있습니다. 다음과 같은 조건을 따라야 합니다: 저작자표시. 귀하는 원저작자를 표시하여야 합니다. 비영리. 귀하는 이 저작물을 영리 목적으로 이용할 수 없습니다. 변경금지. 귀하는 이 저작물을 개작, 변형 또는 가공할 수 없습니다. l 귀하는, 이 저작물의 재이용이나 배포의 경우, 이 저작물에 적용된 이용허락조건 을 명확하게 나타내어야 합니다. l 저작권자로부터 별도의 허가를 받으면 이러한 조건들은 적용되지 않습니다. 저작권법에 따른 이용자의 권리는 위의 내용에 의하여 영향을 받지 않습니다. 이것은 이용허락규약(Legal Code)을 이해하기 쉽게 요약한 것입니다. Disclaimer 약학 석사학위 논문 안지오텐신 전환 효소 억제제 개시 이후 진해제의 사용 분석 Use of Antitussives After the Initiation of Angiotensin-Converting Enzyme Inhibitors 2017년 8월 서울대학교 대학원 약학과 사회약학전공 권 익 태 안지오텐신 전환 효소 억제제 개시 이후 진해제의 사용 분석 Use of Antitussives After the Initiation of Angiotensin-Converting Enzyme Inhibitors 지도교수 홍 송 희 이 논문을 권익태 석사학위논문으로 제출함 2017년 4월 서울대학교 대학원 약학과 사회약학전공 권 익 태 권익태의 석사학위논문을 인준함 2017년 6월 위 원 장 (인) 부 위 원 장 (인) 위 원 (인) Abstract Use of Antitussives After the Initiation of Angiotensin-Converting Enzyme Inhibitors Ik Tae Kwon Department of Social Pharmacy College of Pharmacy, Seoul National University Background Angiotensin-converting enzyme inhibitors (ACEI) can induce a dry cough, more frequently among Asians. If healthcare professionals fail to detect coughs induced by an ACEI, patients are at risk of getting antitussives inappropriately instead of discontinuing ACEI. The purpose of this study was to examine how the initiation of ACEI affects the likelihood of antitussive uses compared with the initiation of Angiotensin Receptor Blocker (ARB) and to determine the effect of the antitussive use on the duration and adherence of therapy in a Korean population. -
Helicidine, Un Extrait Doses May Be Given
1562 Cough Suppressants Expectorants Mucolytics and Nasal Decongestants UK preparations suggest that these doses be given up to a maxi- ◊ References. Ipecacuanha mum of 4 times daily, although in other countries higher total 1. Pons F, et al. L’effect bronchorelaxant de l’helicidine, un extrait doses may be given. d’Helix pomatia, fait intervenir une liberation de prostaglandine Hlavěnkový kořen; Ipecac; Ipecacuana; Ipécacuanha, racine d’; E2. Pathol Biol (Paris) 1999; 47: 73–80. Respiratory disorders. An FDA review of preparations avail- Ipecacuanha Root; Ipecacuanhae radix; Ipekakuána-gyökér; able over-the-counter concluded that guaifenesin was an effec- Preparations Ipekakuananjuuri (ipecacuanha root); Ipekakuanarot (ipecacuan- tive expectorant.1 The use of expectorants for productive cough Proprietary Preparations (details are given in Part 3) ha root); Ipekakuanu˛ šaknys; Korzeń ipekakuany; Raíz de ipecac- 2 uana. is discussed on p.1547. A small study found that guaifenesin Multi-ingredient: Ger.: Original Schneckensirup†. also appeared to reduce cough reflex sensitivity in patients with Ипекакуана upper respiratory-tract infections, which produce a transient in- CAS — 8012-96-2. crease in sensitivity, although it had no effect on cough reflex in ATC — R05CA04; V03AB01. Indanazoline Hydrochloride (rINNM) ⊗ healthy subjects. The mechanism for this effect was unclear. ATC Vet — QR05CA04; QV03AB01. Guaifenesin has been given to patients with altered nasal muco- Hidrocloruro de indanazolina; Indanazolin Hidroklorür; Indana- 3 Pharmacopoeias. In Eur. (see p.vii), Int., Jpn, and US. ciliary clearance associated with HIV infection. zoline, Chlorhydrate d’; Indanazolini Hydrochloridum. 1. Thomas J. Guaiphenesin—an old drug now found to be effective. Eur., Jpn, and US also include a monograph for Prepared Ipecac- Aust J Pharm 1990; 71: 101–3. -
Estonian Statistics on Medicines 2016 1/41
Estonian Statistics on Medicines 2016 ATC code ATC group / Active substance (rout of admin.) Quantity sold Unit DDD Unit DDD/1000/ day A ALIMENTARY TRACT AND METABOLISM 167,8985 A01 STOMATOLOGICAL PREPARATIONS 0,0738 A01A STOMATOLOGICAL PREPARATIONS 0,0738 A01AB Antiinfectives and antiseptics for local oral treatment 0,0738 A01AB09 Miconazole (O) 7088 g 0,2 g 0,0738 A01AB12 Hexetidine (O) 1951200 ml A01AB81 Neomycin+ Benzocaine (dental) 30200 pieces A01AB82 Demeclocycline+ Triamcinolone (dental) 680 g A01AC Corticosteroids for local oral treatment A01AC81 Dexamethasone+ Thymol (dental) 3094 ml A01AD Other agents for local oral treatment A01AD80 Lidocaine+ Cetylpyridinium chloride (gingival) 227150 g A01AD81 Lidocaine+ Cetrimide (O) 30900 g A01AD82 Choline salicylate (O) 864720 pieces A01AD83 Lidocaine+ Chamomille extract (O) 370080 g A01AD90 Lidocaine+ Paraformaldehyde (dental) 405 g A02 DRUGS FOR ACID RELATED DISORDERS 47,1312 A02A ANTACIDS 1,0133 Combinations and complexes of aluminium, calcium and A02AD 1,0133 magnesium compounds A02AD81 Aluminium hydroxide+ Magnesium hydroxide (O) 811120 pieces 10 pieces 0,1689 A02AD81 Aluminium hydroxide+ Magnesium hydroxide (O) 3101974 ml 50 ml 0,1292 A02AD83 Calcium carbonate+ Magnesium carbonate (O) 3434232 pieces 10 pieces 0,7152 DRUGS FOR PEPTIC ULCER AND GASTRO- A02B 46,1179 OESOPHAGEAL REFLUX DISEASE (GORD) A02BA H2-receptor antagonists 2,3855 A02BA02 Ranitidine (O) 340327,5 g 0,3 g 2,3624 A02BA02 Ranitidine (P) 3318,25 g 0,3 g 0,0230 A02BC Proton pump inhibitors 43,7324 A02BC01 Omeprazole -
Ied with Great Restlessness
excessive discharge from the bowels. Subsultus tendinum plete publicity lies with Ayer; whether correctly or not, the in the terminal stage of the disease is usually accompan- quantities are all given. AYER'S rECTORAL. PRUNI-HEEOIN. ied with for which in recent cases I CHERRY great restlessness; Each auid ounce1 represents Each fluid ounce represents have found Hoffman's as recommended Wild cherry .6 grains. Wild cherry bark. anodyne, by White pine .4 White bark. a grains. pine Hare, very useful remedy. Terpin hydrate. .. .4 grains. Terpin hydrate.4 grains. In the later of the feeble heart's Blood root .2 grains. Blood root. stage typhoid fever, Heroin ( !).1/6 grain. Heroin .1/6 grain. action calls for and one must instruct the Grindella rohusta. .4 grains. Ammon muriate. .16 grains. support; Senega .4 grains. Spikenard. nurse relative to the necessary stimulants to sustain the Rio Ipecac .2 grains. Glycerin. circulation. the urine is loaded Glycerin. Solvents. During convalescence Alcohol .80 m. etc. with the bacillus. in 5- Syrup. typhoid Hexamethylenamin Water. three times a well diluted with grain doses, repeated day, If Ayer's "shotgun" Pectoral ought "to be considered obso- and continued for a week or ten will water, days, destroy lete, what shall we say of Pruni-Heroin? If a pre- the bacillus in urine. physician the scribe Pruni-Heroin and condemn Ayer's to a patient who has taken Ayer's, what will the patient think of the advice if he learns the of composition Pruni-Heroin? _ Expectorants in the Pharmocopeia. THE PHYSICIAN AND THE PHARMACOPEIA. -
How to Anesthetize Donkeys for Surgical Procedures in the Field
DRUGS AND ANESTHESIA How to Anesthetize Donkeys for Surgical Procedures in the Field Lori A. Bidwell, DVM, Diplomate ACVA Author’s address: Ross University School of Veterinary Medicine, PO Box 334, St. Kitts, West Indies; e-mail: [email protected]. © 2010 AAEP. 1. Introduction ing a local block where a catheter will be placed and Donkeys are an important part of the work force in making a small skin incision with a surgical blade much of the world. Practitioners working with before placing an intravenous catheter is recom- donkeys in the United States and those participat- mended. Intubation is more difficult because of ing in equitarian initiatives abroad should under- caudal angulation of the larynx, a pharyngeal diver- stand the difference between donkeys and horses in ticulum, excess pharyngeal mucosa, and long paired relation to anesthesia. Although it is tempting to laryngeal saccules. Additionally, nasal intubation 1 treat a donkey like a horse, there are important is complicated by narrow nasal passages. Drug differences in relation to handling and drug doses. metabolism is elevated in donkeys compared with Additionally, it is important to understand alterna- horses, resulting in the use of higher doses and more 2–6 tive anesthetic protocols because a practitioner may frequent dosing intervals. The only known ex- be limited to minimal or alternative drugs when ception to this is the administration of guaifenesin, working in a developing country. which seems to require lower dosing because respi- ratory arrest is easy to achieve when using doses 7 2. Behavior and Physiology appropriate for a horse. A tame donkey can be easy to handle but a feral or minimally handled donkey can be frustrating. -
Pharmaceutical Preparations, Except Biologicals (Manufacturers)
CURRENT INDUSTRIAL REPORTS 2006 MA325G — PHARMACEUTICAL PREPARATIONS, EXCEPT BIOLOGICALS (MANUFACTURERS) DEFINITIONS AND SPECIAL INSTRUCTIONS 1. Scope of survey Products bought and resold without further manufacture should not be included in shipments. This survey covers manufacturers of pharmaceutical preparations, except biologicals, in the United States, Establishments shipping dosage forms, in bulk and and includes all preparations which can be dispensed requiring repackaging, to other establishments of the in measured portions to produce the therapeutic effect same company, should report in column (4) a transfer for which the preparation is most commonly employed value reflecting only services or operations performed (liquids, tablets, pills, capsules, lozenges, powders, including profit (or loss) normally assigned to the ointments, jellies, salves, inhaler tubes, etc.). Products manufacturing establishment. For plants shipping manufactured in Puerto Rico or other U.S. possessions similar products to other companies for repackaging should be excluded. report in column (4) dosage forms shipped in bulk at net sales value as defined above. 2. Figures to be reported Commercial shipments (packaged for consumer use) Companies with more than one establishment Report the value of each drug product produced manufacturing the products covered by this survey are in dosage form, packaged for consumer use and requested to complete a separate report form for each shipped from this establishment to sales branches, location. If you have not received a separate form for warehouses of your company, wholesale or retail each of your establishments, please call the contact stores, and other commercial customers such as listed on the report form or write to the U.S. Census hospitals, institutions, etc.