Pest Control Technical Note - Rodents Number 16 Updated January 2018
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Calarp) Program
California Accidental Release Prevention (CalARP) Program Administering Agency Guidance January 31, 2005 Preface This document provides general guidance to help Administering Agencies (AAs) implement and enforce the California Accidental Release Prevention (CalARP) Program. The intent is to identify the elements of the Program applicable to each regulated business, and assist AAs with oversight of the CalARP Program statutes and regulations. This document is not a substitute for the CalARP Program regulations; it does not impose legally binding requirements. About This Document This document follows the format of the California Code of Regulations, Title 19, Division 2, Chapter 4.5: California Accidental Release Prevention (CalARP) Program. The regulatory sections are presented in parentheses for ease of reference. Acknowledgements The California Emergency Management Agency (Cal EMA) would like to thank the following people for their valuable assistance in the preparation of this document: Howard Wines, Hazardous Materials Specialist, City of Bakersfield Fire Department Robert Distaso P.E., Fire Safety Engineer, Orange County Fire Authority Randall L. Sawyer, Supervisor, Accidental Release Prevention Programs, Contra Costa County Health Services Department Beronia Beniamine, Senior Hazardous Materials Specialist, Stanislaus County Environmental Resources Department Angie Proboszcz, Risk Management Program Coordinator, USEPA Region 9 Jon Christenson, Senior Environmental Health Specialist, Merced County Department of Public Health Teresa -
Pharmacokinetics of Anticoagulant Rodenticides in Target and Non-Target Organisms Katherine Horak U.S
University of Nebraska - Lincoln DigitalCommons@University of Nebraska - Lincoln USDA National Wildlife Research Center - Staff U.S. Department of Agriculture: Animal and Plant Publications Health Inspection Service 2018 Pharmacokinetics of Anticoagulant Rodenticides in Target and Non-target Organisms Katherine Horak U.S. Department of Agriculture, [email protected] Penny M. Fisher Landcare Research Brian M. Hopkins Landcare Research Follow this and additional works at: https://digitalcommons.unl.edu/icwdm_usdanwrc Part of the Life Sciences Commons Horak, Katherine; Fisher, Penny M.; and Hopkins, Brian M., "Pharmacokinetics of Anticoagulant Rodenticides in Target and Non- target Organisms" (2018). USDA National Wildlife Research Center - Staff Publications. 2091. https://digitalcommons.unl.edu/icwdm_usdanwrc/2091 This Article is brought to you for free and open access by the U.S. Department of Agriculture: Animal and Plant Health Inspection Service at DigitalCommons@University of Nebraska - Lincoln. It has been accepted for inclusion in USDA National Wildlife Research Center - Staff ubP lications by an authorized administrator of DigitalCommons@University of Nebraska - Lincoln. Chapter 4 Pharmacokinetics of Anticoagulant Rodenticides in Target and Non-target Organisms Katherine E. Horak, Penny M. Fisher, and Brian Hopkins 1 Introduction The concentration of a compound at the site of action is a determinant of its toxicity. This principle is affected by a variety of factors including the chemical properties of the compound (pKa, lipophilicity, molecular size), receptor binding affinity, route of exposure, and physiological properties of the organism. Many compounds have to undergo chemical changes, biotransformation, into more toxic or less toxic forms. Because of all of these variables, predicting toxic effects and performing risk assess- ments of compounds based solely on dose are less accurate than those that include data on absorption, distribution, metabolism (biotransformation), and excretion of the compound. -
Studies in Microencapsula Tion of Rodenticides
STUDIES IN MICROENCAPSULA TION OF RODENTICIDES P. B. CORNWEL,.L, Director of Research, Rentokil Laboratories ltd., Felcourt, E. Grinstead, Sussex, England ABSTRACT: Warfarln, zinc phosphide, norbormlde and alphachloralose have been mlcroencapsu lated by the technique of coacervatlon and fed to laboratory rats (R. norveglcus) and mice (H. mU$CUlus). Results are given of experiments In which the concentration of rodentlclde, wall material and phase ratio have been varied separately and in combination. Experiments are also repot'ted In which normal and encapsulated rodentlclde have been fed together In the same test diet. Hlcroencapsulatlon can Increase the Intake of rodentlcldes, appreciably, whether or not alternative food is simultaneously available. Nevertheless, significantly higher kills from higher Intakes of poison have not been achieved, Indicating difficulties In optimising the characteristics of the capsule wall to achieve the desired release of Ingested active In gredient. INTl\ODUCTION Hlcroencapsulatlon can be defined as a chemical process by which minute amounts of solids or liquids are enclosed within a thin wall of suitable material to prevent their reaction with some component of the environment. The properties of the wall are so designed to keep the reactive materials apart until they are required to mix. Hlcroencapsulatlon, as an Industrial process, has been developed for many applications by the Natlon~l Cash Register Co. These Include carbonless copying paper, drugs with design ed release characteristics, as well as uses In the perfumery, adhesive and food Industries (Gordon, 1965) . The costs vary from 40 U.S. cents to $4 per kg. of encapsulated material (Watson, 1970) and many future applications have been proposed. -
Studies in Microencapsulation of Rodenticides
View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by DigitalCommons@University of Nebraska University of Nebraska - Lincoln DigitalCommons@University of Nebraska - Lincoln Proceedings of the 4th Vertebrate Pest Vertebrate Pest Conference Proceedings Conference (1970) collection March 1970 STUDIES IN MICROENCAPSULATION OF RODENTICIDES P. B. Cornwell Rentokil Laboratories Ltd., Sussex, England Follow this and additional works at: https://digitalcommons.unl.edu/vpcfour Part of the Environmental Health and Protection Commons Cornwell, P. B., "STUDIES IN MICROENCAPSULATION OF RODENTICIDES" (1970). Proceedings of the 4th Vertebrate Pest Conference (1970). 18. https://digitalcommons.unl.edu/vpcfour/18 This Article is brought to you for free and open access by the Vertebrate Pest Conference Proceedings collection at DigitalCommons@University of Nebraska - Lincoln. It has been accepted for inclusion in Proceedings of the 4th Vertebrate Pest Conference (1970) by an authorized administrator of DigitalCommons@University of Nebraska - Lincoln. STUDIES IN MICROENCAPSULATION OF RODENTICIDES P. B. CORNWELL, Director of Research, Rentokil Laboratories Ltd., Felcourt, E. Grinstead, Sussex, England ABSTRACT: Warfarin, zinc phosphide, norbormide and alphachloralose have been microencapsulated by the technique of coacervation and fed to laboratory rats (R. norvegicus) and mice (M. musculus). Results are given of experiments in which the concentration of rodenticide, wall material and phase ratio have been varied separately and in combination. Experiments are also reported in which normal and encapsulated rodenticide has been fed together in the same test diet. Microencapsulation can increase the intake of rodenticides, appreciably, whether or not alternative food is simultaneously available. Nevertheless, significantly higher k i l l s from higher intakes of poison have not been achieved, indicating difficulties in optimising the characteristics of the capsule wall to achieve the desired release of ingested active in- gredient. -
Assessing the Sustainability of Anticoagulant-Based Rodent Control for Wildlife Conservation in New Zealand
Copyright is owned by the Author of the thesis. Permission is given for a copy to be downloaded by an individual for the purpose of research and private study only. The thesis may not be reproduced elsewhere without the permission of the Author. Assessing the sustainability of anticoagulant-based rodent control for wildlife conservation in New Zealand A thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Conservation Biology at Massey University, Palmerston North, New Zealand SUMAN PREET KAUR SRAN 2019 1 I dedicate this thesis to My Grandmother, Baljinder Kaur Sran who has loved and supported me unconditionally 2 Table of Contents Acknowledgements ....................................................................................................................... 7 Abstract ......................................................................................................................................... 9 Glossary of Key Terms related to Anticoagulant Resistance ...................................................... 11 CHAPTER 1 Introduction ............................................................................................................. 13 Rodents in New Zealand ......................................................................................................... 14 Rattus rattus ........................................................................................................................... 14 Mus musculus ......................................................................................................................... -
The List of Extremely Hazardous Substances)
APPENDIX A (THE LIST OF EXTREMELY HAZARDOUS SUBSTANCES) THRESHOLD REPORTABLE INVENTORY RELEASE QUANTITY QUANTITY CAS NUMBER CHEMICAL NAME (POUNDS) (POUNDS) 75-86-5 ACETONE CYANOHYDRIN 500 10 1752-30-3 ACETONE THIOSEMICARBAZIDE 500/500 1,000 107-02-8 ACROLEIN 500 1 79-06-1 ACRYLAMIDE 500/500 5,000 107-13-1 ACRYLONITRILE 500 100 814-68-6 ACRYLYL CHLORIDE 100 100 111-69-3 ADIPONITRILE 500 1,000 116-06-3 ALDICARB 100/500 1 309-00-2 ALDRIN 500/500 1 107-18-6 ALLYL ALCOHOL 500 100 107-11-9 ALLYLAMINE 500 500 20859-73-8 ALUMINUM PHOSPHIDE 500 100 54-62-6 AMINOPTERIN 500/500 500 78-53-5 AMITON 500 500 3734-97-2 AMITON OXALATE 100/500 100 7664-41-7 AMMONIA 500 100 300-62-9 AMPHETAMINE 500 1,000 62-53-3 ANILINE 500 5,000 88-05-1 ANILINE,2,4,6-TRIMETHYL- 500 500 7783-70-2 ANTIMONY PENTAFLUORIDE 500 500 1397-94-0 ANTIMYCIN A 500/500 1,000 86-88-4 ANTU 500/500 100 1303-28-2 ARSENIC PENTOXIDE 100/500 1 THRESHOLD REPORTABLE INVENTORY RELEASE QUANTITY QUANTITY CAS NUMBER CHEMICAL NAME (POUNDS) (POUNDS) 1327-53-3 ARSENOUS OXIDE 100/500 1 7784-34-1 ARSENOUS TRICHLORIDE 500 1 7784-42-1 ARSINE 100 100 2642-71-9 AZINPHOS-ETHYL 100/500 100 86-50-0 AZINPHOS-METHYL 10/500 1 98-87-3 BENZAL CHLORIDE 500 5,000 98-16-8 BENZENAMINE, 3-(TRIFLUOROMETHYL)- 500 500 100-14-1 BENZENE, 1-(CHLOROMETHYL)-4-NITRO- 500/500 500 98-05-5 BENZENEARSONIC ACID 10/500 10 3615-21-2 BENZIMIDAZOLE, 4,5-DICHLORO-2-(TRI- 500/500 500 FLUOROMETHYL)- 98-07-7 BENZOTRICHLORIDE 100 10 100-44-7 BENZYL CHLORIDE 500 100 140-29-4 BENZYL CYANIDE 500 500 15271-41-7 BICYCLO[2.2.1]HEPTANE-2-CARBONITRILE,5- -
The Evaluation of Alternative Toxins to Sodium Monofluoroacetate (1080) for Possum Control
View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by UNL | Libraries University of Nebraska - Lincoln DigitalCommons@University of Nebraska - Lincoln Proceedings of the Fifteenth Vertebrate Pest Vertebrate Pest Conference Proceedings Conference 1992 collection March 1992 THE EVALUATION OF ALTERNATIVE TOXINS TO SODIUM MONOFLUOROACETATE (1080) FOR POSSUM CONTROL Charles T. Eason Forest Research Institute, P.O. Box 31-011, Christchurch, New Zealand Follow this and additional works at: https://digitalcommons.unl.edu/vpc15 Part of the Environmental Health and Protection Commons Eason, Charles T., "THE EVALUATION OF ALTERNATIVE TOXINS TO SODIUM MONOFLUOROACETATE (1080) FOR POSSUM CONTROL" (1992). Proceedings of the Fifteenth Vertebrate Pest Conference 1992. 24. https://digitalcommons.unl.edu/vpc15/24 This Article is brought to you for free and open access by the Vertebrate Pest Conference Proceedings collection at DigitalCommons@University of Nebraska - Lincoln. It has been accepted for inclusion in Proceedings of the Fifteenth Vertebrate Pest Conference 1992 by an authorized administrator of DigitalCommons@University of Nebraska - Lincoln. THE EVALUATION OF ALTERNATIVE TOXINS TO SODIUM MONOFLUOROACETATE (1080) FOR POSSUM CONTROL CHARLES T. EASON, Forest Research Institute, P.O. Box 31-011, Christchurch, New Zealand ABSTRACT: Possum control in New Zealand is dependent on the use of sodium monofluroacetate (1080) and cyanide. Although 1080 is highly effective, its use is restricted to government staff. Cyanide is available for a wider group of licensed operators, but cyanide "shyness" reduces its effectiveness. An acute toxicity programme has been set up to identify non- anticoagulant toxins that could be used safely by farmers. Dose-ranging studies showed that possums are susceptible to cholecalciferol, calciferol, gliftor, alpha-chloralose, and nicotine, but not to bromethalin. -
RRAC Guidelines on Anticoagulant Rodenticide Resistance Management Editor: Rodenticide Resistance Action Committee (RRAC) of Croplife International Aim
RRAC guidelines on Anticoagulant Rodenticide Resistance Management Editor: Rodenticide Resistance Action Committee (RRAC) of CropLife International Aim This document provides guidance to advisors, national authorities, professionals, practitioners and others on the nature of anticoagulant resistance in rodents, the identification of anticoagulant resistance, strategies for rodenticide application that will avoid the development of resistance and the management of resistance where it occurs. The Rodenticide Resistance Action Committee (RRAC) is a working group within the framework of CropLife International. Participating companies include: Bayer CropScience, BASF, LiphaTech S. A., PelGar, Rentokil Initial, Syngenta and Zapi. Senior technical specialists, with specific expertise in rodenticides, represent their companies on this committee. The RRAC is grateful to the following co-authors: Stefan Endepols, Alan Buckle, Charlie Eason, Hans-Joachim Pelz, Adrian Meyer, Philippe Berny, Kristof Baert and Colin Prescott. Photos provided by Stefan Endepols. Contents 1. Introduction ............................................................................................................................................................................................................. 2 2. Classification and history of rodenticide compounds ..............................................................................................3 3. Mode of action of anticoagulant rodenticides, resistance mechanisms, and resistance mutations ......................................................................................................6 -
Anticolagulant Resistance in the UK
Anticoagulant Resistance in the United Kingdom History of resistance Anticoagulants were introduced into the United Kingdom in the early 1950s. Their introduction revolutionized rodent control, providing a far more effective method of controlling rodents compared with the previously available acute rodenticides. The acute rodenticides (zinc phosphide, alpha-naphthylthiourea, 1080, 1081, thallium) were relatively inefficient as a result of their poor palatability, fast action (mins/hours) and relatively painful impact. Many rodents, either failed to eat the baits or only consumed sub-lethal doses. Those that survived sub-lethal dosing often acquired bait and poison shyness, avoiding further attempts to poison them. Even with pre-baiting it was not easy to average more than 70% mortality in practical situations. The introduction of warfarin and above: Rodents are carriers of at least 45 diseases and 200 human pathogens. subsequently other anticoagulants provided a far more effective means of products were launched populations of and the term “First Generation controlling rodent infestations and if Norway rats (Rattus norvegicus) and Anticoagulants (FGARs)” used to identify applied correctly, 100% mortality could be House mice (Mus musculus) had the earlier anticoagulants. expected. This increased efficiency was developed resistance to these early In the 1980s and 1990s further SGARs due to the chronic nature of anticoagulants. anticoagulants and could consume appeared in the U.K. market, these were They were generally far more palatable considerable amounts of bait and survive. brodifacoum, flocoumafen and most than the acute rodenticides as they used These rodents were termed Warfarin- recently difethialone. By the late 1970s, much lower concentrations of active resistant rodents, although a high level of populations of Norway rats were identified substance and they had a much slower cross resistance existed between all as resistant to difenacoum and also later mode of action and slower onset of these early anticoagulants. -
Hazardous Materials List
Hazardous Materials List Version: 1.12.2016 v 1.4 All agrochemicals, especially pesticides, can be potentially hazardous in some form or other to human and animal health as well as to the environment and therefore should be used only under caution. Fairtrade International recommends the use of other methods like proper choice of crops and varieties, suitable cultivation practices and biological material for pest, before a chemical pesticide is used for pest control. The Hazardous Materials List (HML) is divided in three lists: the Red List, the Orange List and the Yellow List. Red List: The Red List is a ‘prohibited’ list and includes materials that must not be used on Fairtrade products. Orange List: The Orange List is a ‘restricted’ List and includes materials that may be used under conditions specified in this document thus restricting their use. The use of materials in this list will be monitored by Fairtrade International. Operators should be aware that some of these materials are to be phased out by 30 June 2020 or by 30 June 2022 as indicated in the list. The other materials in the list may eventually be prohibited and are encouraged to abandon their use. Yellow List: The Yellow List is a ‘flagged’ list and includes materials which are flagged for being hazardous and should be used under extreme caution. Fairtrade International will be monitoring the classification of these materials by international bodies like PAN, WHO and FAO, and materials may be prohibited in the future. Operators are encouraged to abandon their use. Classification of materials in the HML The Hazardous Materials List includes materials that are identified as Highly Hazardous as defined in the Code of Conduct on Pesticide Management adopted by FAO and WHO in 2013. -
High Hazard Chemical Policy
Environmental Health & Safety Policy Manual Issue Date: 2/23/2011 Policy # EHS-200.09 High Hazard Chemical Policy 1.0 PURPOSE: To minimize hazardous exposures to high hazard chemicals which include select carcinogens, reproductive/developmental toxins, chemicals that have a high degree of toxicity. 2.0 SCOPE: The procedures provide guidance to all LSUHSC personnel who work with high hazard chemicals. 3.0 REPONSIBILITIES: 3.1 Environmental Health and Safety (EH&S) shall: • Provide technical assistance with the proper handling and safe disposal of high hazard chemicals. • Maintain a list of high hazard chemicals used at LSUHSC, see Appendix A. • Conduct exposure assessments and evaluate exposure control measures as necessary. Maintain employee exposure records. • Provide emergency response for chemical spills. 3.2 Principle Investigator (PI) /Supervisor shall: • Develop and implement a laboratory specific standard operation plan for high hazard chemical use per OSHA 29CFR 1910.1450 (e)(3)(i); Occupational Exposure to Hazardous Chemicals in Laboratories. • Notify EH&S of the addition of a high hazard chemical not previously used in the laboratory. • Ensure personnel are trained on specific chemical hazards present in the lab. • Maintain Material Safety Data Sheets (MSDS) for all chemicals, either on the computer hard drive or in hard copy. • Coordinate the provision of medical examinations, exposure monitoring and recordkeeping as required. 3.3 Employees: • Complete all necessary training before performing any work. • Observe all safety -
Rodent Control in India
Integrated Pest Management Reviews 4: 97–126, 1999. © 1999 Kluwer Academic Publishers. Printed in the Netherlands. Rodent control in India V.R. Parshad Department of Zoology, Punjab Agricultural University, Ludhiana 141004, India (Tel.: 91-0161-401960, ext. 382; Fax: 91-0161-400945) Received 3 September 1996; accepted 3 November 1998 Key words: agriculture, biological control, campaign, chemosterilent, commensal, control methods, economics, environmental and cultural methods, horticulture, India, pest management, pre- and post-harvest crop losses, poultry farms, rodent, rodenticide, South Asia, trapping Abstract Eighteen species of rodents are pests in agriculture, horticulture, forestry, animal and human dwellings and rural and urban storage facilities in India. Their habitat, distribution, abundance and economic significance varies in different crops, seasons and geographical regions of the country. Of these, Bandicota bengalensis is the most predominant and widespread pest of agriculture in wet and irrigated soils and has also established in houses and godowns in metropolitan cities like Bombay, Delhi and Calcutta. In dryland agriculture Tatera indica and Meriones hurrianae are the predominant rodent pests. Some species like Rattus meltada, Mus musculus and M. booduga occur in both wet and dry lands. Species like R. nitidus in north-eastern hill region and Gerbillus gleadowi in the Indian desert are important locally. The common commensal pests are Rattus rattus and M. musculus throughout the country including the islands. R. rattus along with squirrels Funambulus palmarum and F. tristriatus are serious pests of plantation crops such as coconut and oil palm in the southern peninsula. F. pennanti is abundant in orchards and gardens in the north and central plains and sub-mountain regions.