2020 Report in PDF Format
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TABLE OF CONTENTS 1. LIST OF ACRONYMS ...........................................................5 2. EXECUTIVE SUMMARY ........................................................9 3. PRESENT, PERSPECTIVES AND CHALLENGES ..................................10 3.1 The Institute in 2020 ....................................................................... 10 3.2 The Institute’s organization and governance . 11 3.3 The Governing Bodies’ Main Recommendations in 2020 ...................................... 12 3.3.1 Main comments from the 2020 Liaison Council meeting (27 May 2020) ...............................................12 3.3.2 Main recommendations of the Scientific Advisory Board meeting (1-4 February 2021) .................................12 3.4 Institutional objectives .................................................................... 13 3.4.1 IPC continues to develop its partnerships . .13 3.4.2 IPC continues to develop scientific capabilities ......................................................................16 3.4.3 IPC continues to develop its infrastructure ..........................................................................17 3.4.4 IPC continues to develop its staff and to make careers attractive .....................................................18 3.4.5 IPC continues to develop its visibility and shares its scientific perspectives ............................................19 3.4.6 Publications ......................................................................................................21 3.4.7 IPC strengths and challenges.......................................................................................21 4. 2020 ACTIVITIES AT INSTITUT PASTEUR DU CAMBODGE ........................ 23 4.1 Malaria Molecular Epidemiology Unit ....................................................... 23 4.1.1 Functional structure ...............................................................................................23 4.1.2 Research Programs – Major Achievements in 2020...................................................................24 4.1.3 Research Programs –Outlook for 2021..............................................................................27 4.1.4 Support to National Authorities ....................................................................................29 4.1.5 Teaching and Training .............................................................................................29 4.1.6 Publication List....................................................................................................29 4.2 Epidemiology & Public Health Unit .......................................................... 31 4.2.1 Functional structure . .31 4.2.2 Research Programs - Major Achievements In 2020 ...................................................................32 4.2.3 Research Programs - Outlook for 2021..............................................................................37 4.2.4 Support to National Authorities ....................................................................................38 4.2.5 Teaching and Training .............................................................................................38 4.2.6 Publications List...................................................................................................39 4.2.7 Perspectives of the Epidemiology and Public Health Unit.............................................................41 4.3 Immunology Unit ......................................................................... 42 4.3.1 Functional structure ...............................................................................................42 4.3.2 Research Programs – Major Achievements In 2020...................................................................42 4.3.3 Research Programs – Outlook for 2021 .............................................................................44 4.3.4 Support to National Authorities ....................................................................................48 4.3.5 Teaching and Training .............................................................................................48 4.3.6 Publication List....................................................................................................48 Institut Pasteur du Cambodge 1 /108 4.4 Virology Unit .............................................................................. 50 4.4.1 Functional Structure ..............................................................................................50 4.4.2 Research Programs - Major Achievements in 2020 . .51 4.4.3 Research Programs –Outlook for 2021..............................................................................67 4.4.4 Other Pending Funding for Research Programs......................................................................69 4.4.5 Support to National Authorities ....................................................................................71 4.4.6 Teaching and Training .............................................................................................74 4.4.7 Publication List ...................................................................................................75 4.5 Medical and Veterinary Entomology Unit .................................................... 78 4.5.1 Functional Structure ..............................................................................................78 4.5.2 Research Programs – Major Achievements in 2020...................................................................78 4.5.3 Research Programs – Outlook for 2021 .............................................................................81 4.5.4 Support to National authorities ....................................................................................82 4.5.5 Teaching and Training .............................................................................................83 4.5.6 Publications List...................................................................................................84 4.6 Laboratory for Environment and Food Safety ................................................ 85 4.6.1 Functional Structure ..............................................................................................85 4.6.2 Daily Activities 2020...............................................................................................85 4.6.3 Research Programs - Major Achievements in 2020 . .86 4.6.4 Research Programs - Outlook for 2021..............................................................................88 4.6.5 Support to National Authorities ....................................................................................89 4.6.6 Teaching and Training .............................................................................................89 4.6.7 Outlook for Upcoming 3 - 5 Years ...................................................................................89 4.7 Medical Biology Laboratory ................................................................ 90 4.7.1 Functional Structure ..............................................................................................90 4.7.2 Daily Activities ....................................................................................................90 4.7.3 Research Programs – Major Achievements in 2020...................................................................94 4.7.4 Research Programs – Outlook for 2021 .............................................................................97 4.7.5 Support to National Authorities ...................................................................................100 4.7.6 Teaching and Training ............................................................................................100 4.7.7 Publication List 2020 .............................................................................................101 4.8 Vaccination Center ........................................................................102 4.8.1 Functional Structure..............................................................................................102 4.8.2 Rabies Prevention Centers ........................................................................................102 4.8.3 Vaccination International Center ..................................................................................105 4.8.4 Vaccination Center Vision for Next 2-5 Years .......................................................................106 5. CONCLUSION . 107 6. ANNEX .................................................................... 108 2 /108 Institut Pasteur du Cambodge Institut Pasteur du Cambodge 3 /108 4 /108 Institut Pasteur du Cambodge 1. LIST OF ACRONYMS ACIP Action Concertée Inter-Pasteurienne (Institut Pasteur) ACT Artemisinin combination-based resistance ADE Antibody-Dependent Enhancement AFD Agence Française pour le Développement (French Development Agency) AFRIMS Armed Forces Research Institute for Medical Sciences AFTC Anonymous Free Testing Center AIV Avian Influenza Viruses AMP Antimicrobial Peptides AMR Antimicrobial Resistance Agence Nationale de Recherche sur le SIDA et les Hépatites (French National Agency for AIDS and ANRS Hepatitis Research) AQ Amodiaquine AQ-R Amodiaquine Resistant(ce) ART-R Artemisinin resistant Antibiotic resistance at the Human/Animal/Environment interface in a “One Health” Approach in ARCAHE Cambodia – FSPI project ASAQ Artesunate amodiaquine ASIDE Alerting and Surveillance for Infectious Diseases Epidemics AST Antibiotic