CALIFORNIA TUMOR TISSUE REGISTRY
"TUMORS OF THE KIDNEY & BLADDER"
Study Cases, Subscription A
February 2007
California Tumor Tissue Registry c/o: Department of Pathology and Human Anatomy Lorna Linda University School of Medicine 11021 Campus Avenue, AH 335 Loma Linda, California 92350 (909) 558-4788 FAX: (909) 558-0188 E-mail: [email protected] Target audience: Practicing pathol ogist~ aod pathology residents.
Coal: To acquaint the participant with the histologic featwes of a variety of benign and malignant neoplasms aod tumor-like conditions.
Obiedives: The participant will be able to recognize morphologic features ofa variety of benign and malignant neoplasms and tumor-like conditions and relate those processes to pertinent references in the medical literature.
Educational methods and media: Review of representative glass slides with associated histories. Feedback on consensus diagnoses from participating pathologists. Listing of selected refer:eoces from the medical literature.
Principal faeultv: Donald R. Chnse, MD
CMECredit: Lorna Linda University School of Medicine designates this continuing medical education activity for up to 2 hours ofCategory 1 of the Physician's Recognition Award of the American Medical Association. CME credit is offered for the subscription year only.
Accreditation: Lorna Linda University School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to sponsor continuing medical education for physicians.
2 Study Cases, february 2007, Subscription A Contributor: Carol Solomon, M.D. Case No. 1 - February 2007 A San Diego, CA
Tissue from: Urinary Bladder Accession #30272
Clinical Abstract: A 57 year old man presented with a six month history of intermittent hematuria. Cystoscopy showed a large tumor within the bladder.
Gross Pathology: The 15.5 x 13.7 x 9.5 em bladder was filled by an 8.0 x 4.3 x '"3.7 em fungating papillary tan pink mass, circumferentially adherent to the lower two-thirds of the posterior and anterior bladder walls.
Contributor: Lorna Linda Pathology Group (np) Case No. 2 - February 2007 A Lorna Linda, CA
Tissue from: Urinary Bladder Accession #30203
Clinical Ab~tract : This 83 year old man presented with gross painless hematuria. He had no elevation of his PSA. Cystoscopy showed a large tumor with.in the urinary bladder.
Gross Pathology: The specimen consisted ofan 8 x 6 x 1.5 em aggregate oftransurethrally removed tumor chips.
SIUdy Cases. February 2007. Subscription A 3 Contributor: Lester Thompson, M.D. Case No.3 - February 2007 A Woodland Hills, CA
Tissue from: Urinary Bladder Aeeession #30250
C linical Abstract: This 32 yc;ar old woman presented with vague lower abdominal pain, associated with a history of urinary tract infection. Antibiotics failed to resolve the symptoms and urinalysis showed microscopic hemaruria. Colonoscopy was normal and intraoperative evaluation of ovaries, uterus and appendix showed no abnormal.ities.
Gross Pathology: Not available.
Contributor: Mark Janssen, M.D. Case No. 4 - February 2007 A Auaheim,CA
T issue from: Rigbt kidney Accession #30 147
C linical Abstract After two months of worsening right flank pain, this 73 year old woman was found on CT scan to have a right renal mass. She had had no hematuria or weight loss.
Gross Pathology: The kidney resection specimen was received in fragments. In addition to grossly apparent renal parenchyma, several of the pieces, ranging from 2.7 to 3.2 em in greatest diameter, had firm tan-white cut surfaces. Other fragments were largely fatty and yellow.
Special Studies: Tumor cells positive: vimentin, smooth muscle actin, muscle specific actin, desmin, HMB45 Tumor cells negative: pankeratin
4 Study Cases, February 2007, Subscription A Contributor: Jin Wang, M.D. Case No. 5 - February 2007 A Hangzhou, People's Republic of China
Tissue from: Right kidney Accession #30115
Clinical Abstract: A 35 year old woman presented with vague pain in the right lumbar region and a 20 day history oflow grade fever. Work-up found a right kidney mass.
Gross Pathology: The kidney resection specimen was 14 x 8 x 8 em and contained a 9 x 7 em well-defmed mass in the lower pole. The cut surface was variable, ranging from gray, to pink-tan to dark red. There was extensive necrosis.
Special Studies: Strongly positive: Desmin, SMA, virnentin Focally positive: Actin Negative: Cytokeratin, EMA, MyoD-1
Contributor: Anne Drejet, M.D. Case No. 6 - February 2007 A Santa Barbara, CA
Tissue from: Kidney Accession #30289
<:::linical Abstract: A 58 year old woman was found to have cystic masses involving the right kidney and adrenal gland.
Gross Pathology: Not available.
.Study Cases, February 2007, Subscription A 5 Contributor: Michele Cosgrove, M.D. Case No. 7 - February 2007 A Glendale, CA
Tissue from: Left Kidney Accession #30364
Clinical Abstract: Follow up of aS I year old diabetic man in renal failure revealed a mass in his left kidney.
Gross Pathology: In the mid portion of the 190 gram kidney was a 4.3 x 4.0 X 3.0 em well~ircumscribed hard pale tan mass.
Special Studies: Positive: CD99, CD34, Vimentin Negative: AEI /AE3, CDII7, Desmin, actin
Contributor: Anne Drejet, M.D. Case No. 8 - February 2007 A Santa Barbara, CA
Tissue from: Kidney Accession #30290
Clinical Abstract: A 41 year old woman bad a right kidney mass.
Gross Pathology: The right kidney resection specimen with perinephric fat was 121 0 grams. It was distorted by a 14 x 12 x 10 em tumor which left a thin rim of kidney at one pole. The tumor penetrated the renal capsule, extending into surrounding fat. The cut surface was lobulated dense white parenchyma with focal yellow necrosis.
Special Studies: Positive: C099, vimentin, SMA (focal), CD I 0 Negative: CK-7, CK-20, CAM5.2, EMA, Ber-EP4, myo-DI, CD56, HMB-45, FLI- 1, S-1 00, desmin, CD23, CD 117, Estrogen & Progesterone receptors
6 Srudy Cases, February 2007, Subscription A Contributor: Phillip Gordon, M.D. Case No. 9 - February 2007 A Winter Haven, FL
Tissue from: Left kidney Aroession #30185
Clinical Abstract: A 69 year old woman bad a left renal mass.
Gross Pathology: The 244 gram resection specimen included a 2.5 x 2.3 x 1.5 em _fleshy dark. red-brown mass in the upper pole of the kidney, filling one of the calyces. The mass was diffusely hemorrhagic, well encapsulated and confined to the kidney.
Contributor: Dawn Ellerson, M.D. Case No. 10 - February 2007 A San Luis Obispo, CA
Tissue from: Kidney Accession #30233
Clinical Abstract: An 86 year old woman presented with hematuria. lmaging studies showed a right renal pelvic mass involving the collecting system extending into the mid portion of the kidney.
Gross Pathology: The 284 gram kidney contained a 5 x 4 x 3.5 em ill-defined infiltr.rting mass that extended nearly to the renal capsule.
Study Cases. Febru:uy 2007, Subscription A 7 IZil.
CALIFORNIA TUMOR TISSUE REGISTRY •
.tUMORS -OF THEKJDNEY"AND. BL:A:DDER PA'THOLOlJY
Mjnut~s - Sub.scrip.tion A
-Febl.1laty; 2001
SUGGESTED READING (General Topics from Recent Literature):
Lymphoma Is the Most Common Malignancy of the Ocular Adnexa. Ferry JA, Fnng.CY, el at Am J Surg Pathol 2007; 31:170-184. Women More Likely to Have New or Missed CRC After Colonoscopy. Bressler B, Paszat LF, ct al. Gaiitroenterol 2007; 132:96- 102. .. Mammaglobin Is a Specific Marker for Breast Cancer. Sasaki E,.Tsunoda N, et al. Mod Patilo/2006; 22. T.LE I Ts a Sensitive & Specific Marker for Synovial Sarcomas. Terry J, Saito T, er al. Am J Sw-gPatho/2007; 31:240- 246. Clear Cell Sarcoma. Clinical Fearures, Therapy, & Prognosi.s. Kawai A, Hosono A, et al. Cancer 2007; I 09:109-116.
California Tumor Tissue. Registry c/o: Department of Pathology aod Human Anatomy Lama Linda University School of Medicine 11 021 Campus Avenue , AH 33 5 Loma Linda, California 92350 (909) 558-4788 FAX: (909) 558-0188 E-mail: cttrliillinkline.com Web site & Case of the Month: www·.cttr.org FILE DIAGNOSES
(Preferably submitted on website at www.etir.ore. Click "subscriptions", dten submit answers".)
CTTR Subscription A l"ebrua•·y, 2007
Case 1: Papillary urothe)jaJ carcinoma, bladder T-71000, M-80503
Case 2: Carcinosarcoma (sarcomatoid high grade urothelial carcinoma with chondrosarcoma and osteosarcoma, bladder T-77100,M-92203
Case3: Mucinous adenocarcinoma, bladder T-71000, M-81403
Case4: Angiomyolipoma, kidney T-71000, M-88600
Case 5: Leiomyosarcoma, kidney T-71000, M-88903
Case6: Mixed epithelial and stromal tumor, kidney T-71000, M-81003
Case 7: Solitary fibrous tumor, kidney T-71000, M-90510
Case 8: High grade sarcoma, (NOS), kidney T-71000, M-88103
Case9: Renal cell carcinoma with papi llary and tubulocystic features, l Case JO: Collecting duct carcinoma, kidney T-71000, M-83123 2 CITR, Fcbnmry 2007 "Minutes" (Subscrip(ion A) Case No. l, Accession No. 30272 February 2007 Alameda (Alameda County Medical Center) - Papillary urothclial coroinoma, low grade Eon!3!!a (Kaiser PctlJ!AOrntel - 'l'nlnsitional cell can:inoma, grade 213 Granada Hj!ls - Invasive transitional cell carcinoma. no muscle involvement L&ng peach • Invasive papillary urothelial carcinoma, high grade Long Beach CLone Beach Veterans HosoitaD - Papillary urothelial carcinoma, WHO 2/J L&s Ansclcs • Transitional cell caroinoma Monterey !Community Hospjral of Monterey Peninsula) • Papillary urothe!inl earcinoma, high grade (2); Low grodc (I) ~ • Low grade J>apillary caroinoma Orange IQawge Coumy Pathology Medical Grouo) • Pupillary ~tansitiooal cell carcinoma, low grade Oxnard CSt John's Regjo!l!ll Medical U:ntcc) • Papillary transitional ct:U ClUCinoma, grndc VU, low gl'lde papillary carcinoma (I); Papillary transitional cell carcinoma(2) San Dicgq • Papillary tra.tlsitional ccU carcinoma. focally invasive, grade IJ bladder S;m Diego CNaval Modica! Center San Diego) • Infiltrating urotheliol carcinoma San DicgoiScripos HCi!hhl • Low grade papillary urothclial can:inoltl3 San Diego (l/CSD) • Papillary and sessile urothelial carcinoma, low grade San Francjsco !San Francisco General Hospjual) - Low srade ~rot h c l ial carcinoma San~• Badlam • Low grade papillary urolhellal carcinon~a Santa RosgiSanra Rosa Mcmonal HospitaO • Transitional cell caroinoma (I); Papillary urothclial carcinoma, low grade (I) Papillary transitionnl cell carcinoma, low gmdc (papillary urothclial tumor) (I) Woodland Hms CKaiscr Pcpnsnente) . Non-invasive papillary urothelial carcinoma, low grade Wosxlland Hills CTIR. February 2007 "Mimllcs·· (Subscription A} 3 Brazil. Sao Pnulo - Papillary urothelial carcinoma, high ,gmde Canada !Pasqua Hosoital) • Inverted papilloma Canada, Saskatoon · Papillary urothelial (ITansitional cell carcinoma) carcinoma, low grade Canada £Sherhmoke University Hospital) - Low grade papillary invasive carcinoma lndia,Kamataka - Papillary urothelial neoplasm oflow malignant potential freland CKerry Genera] Hospital) .. Transitional cell carcinoma ofbladdcr Jamaica Case 1 - Diagnosis: Papillary urothelial carcinoma, bladder. T-71000, M-80503 Case 1 - References: Choi YL, Lee SH, Kwon GY, et al. Overexpression ofC024- Association with Invasiveness In Urothelial Carc.inomaof Case No. 2, Accession No- 30203 February 2007 Alameda 4 Cl11{. february 2007 otMinutcs" (Subscription A) Marvland {Northwe~t Hosnital Cenrec) - Sarc·ootaroid urothelial carcinoma Marvland !University of Marvland) • Sarcomatoid carcinoma with high grade urothelial carcinoma component Massachusetts (Berkshire Medical Center) - Sarcomatoid and small cell carcinoma with heterologous elements (chondrosarcoma and osteosarcoma) Massachustt1S (Beverlv Hospital) · Carcinosurcoma vs. pure sarcoma with sarcoma clements of chondrosarcoma Michigan (Qak·wood Hospital) .. Sarcomatoid carcinoma. with background trilllsitional cell in-siru Minnesota (Fairview Ridees Hospital) - Urothelial carcinoma, hjgh grade, with sarcomatoid differentiation Nebraska !Creig-hlon Unive-rsilv School of Medjcjo~) - Carcinosarcoma Ne,vMexico fUniversit.vofNew M'exico) - Sarcomatoid varian( ofurothelial carcinoma with heterologous clements New York (Long Island Jewish Medical Center) - Sarcomatoid transitional cell carcinoma with heterologous elements New York (Nassau Univcrsitv Medical .Ccnter) • Urothelial carcinoma. sarcomatoid New York (Stony Brook Vniversitv Hospital) - Transitional cell carcinoma (high grade) New York CSliNY Do\\'1'1Sfa1e Medical Center) - Sareomato!d c:areinoma vs. sarcoma with rhabdoid differtntiation North Caroljna fMoumajn Area Pathology) - High grade .transitional celf carcinoma and C IS ( I); Sarcomatoid carcinoma (I) Ohio McCullough-Hyde Memorial Hospital) - Chondrosarcoma Oklahoma Tulsa - Urothelial carcinoma heterologous sarcomatoid type (carcinosarcoma) Renosvlyanja (Drexel ()niversitv Colfege ofMedicjoe) - Sarcomatoid (spindle celf) carcinoma of bladder with chondrosarcomatous differentiation (carcinosarcoma) Pennsvlvania (Lehigh Valley Hospital) - Sarcomatoid carcinoma t>ennS}'Ivania (Magee Women's Hospital) - Sarcomatoid carcinoma Pcnn:wlvania CMt. Nittanv Medical Center) - Urothelial carcinoma, heterologous sarcomatoid type Pcnnsylyanis CPcnpsylyanja Hospjtal Residenrs) - Carcinosarcoma Puerto Rico (Universitv of Puerto Rico) • Sarcomatoid (metaplastic) carcinoma South Dakota (lJnivcrs-itv of South Dakota Re.~ i den rs) - Carcinosarcoma Iepnessoe. Kingsp Cas-e: 2- Diagnosis: Carcinosarcoma (sarcomatoid bigh grade urotbelial carcinoma with chondrosarcoma.and osteosarcoma), bladder T-77100, M-92203 C11'R, February 2007 "'Minutes!' (Subscription A) s Case 2 • References: l:foshi S, Sasaki M, Muto A, et a!. Case of Carcinosarcoma ofUr inary Bradder Obtained a Pathologically Complete Response by Neoadjuvant Chemoradiotherapy. lnl J Uro/2007; 14(1 ):79-81. Shah SK, Lui P.D, Baldwjn DD, eta!. Urothelial C~rcinonia After External Beam Radiation Therapy for Prostate Cancer. J Uro/2006; 175(6):2063-2066. Rogers CG, Palapattu GS, Shariat SF, et al. Clinical Outcomes Following Radical Cystectomy for Primary Nontransitional Cell Carcinoma of the Bladder Compared to Transitional Cell Carcinoma of the Bladder. J Urol 2006; 175(6):2048-2053. Jayamoban Y,"Urs L, Rowland RG, eta!. Periurethral Carcinosarcoma. A Report of2 Cases with a Review ofthe Literamre. Arch Pmhol Lab Med 2005; 129{4):e91-93. McKenney JK. An Approach to the Classification ofSpind le Cell Proliferations in the Urinary Bladder. Adv ill Alia/ Patho/2005; 12(6):312-323. Case No. 3, Accession No. 30250 February 2007 Alameda 6 C'rfR, February 2007 "Minutes" (Subsc.ription A} New york £SUNY Down;uate Medjcp! Center) - Mucinous adenocarcinoma, primary North Cnro1ina (Mountain Area Patholony)- Mucinous adenocarcinoma, urachal origin (2} Ohjo fMcCilllouRh-Hyde Memorial t!osoitnl) - Adcnocan:inoma, muconou.s type Oklahoma Tulsa - Mucinous .adenocarcinoma, lJrachul origin Pennsvtyania ffin;xel Unjvsrsiry College o[Mcdjcinel - Mucinous adenocarcinoma (urachal carcinoma) Pennsylvania tlsbjgh Valley Hospjtu]) - Mucinous adenocarcinoma, bladder Pennsylyonia fMHgee Women's 1-Jnspital) - AdenoCO.I'tinoma, lllucinous 1ype Pennsvtvania (MI. Nittaov Medical Center)- Adenocarcinoma, mucinous and stgnct ring type Pennsylvania tPennsvlvan1a Hospitql Residents) - Mucinous adenocarcinoma Pue.rto Rjco lUmvcrsitvofPuerro Rjco) - Mucinous adenoearc i nomulsignet~ring cell adenocarcinoma South Oa!rot;! (Upjygsirv ofSouJb D:!k!!l!! Residents) - Mucinous adenocarcinoma Tennessee Kingsport - Metastatic mucinous (colloid) carcinoma Texas CScott & White Memorial Hosnitall ~ Mucinous adenocnn:inoma Texas Houston • Mucinous adenocarcinoma Texas Lubbock • Muc.inous adenocardnomu Washinmon CaseJ - fJiagno. Case No. 4, Accession No. 30147 February 2007 Alam!XIn (Alameda County Medical Center) - Angiomyolipoma CliR, February 2007 "'Minu1cs" (SubscNption 1\) 7 fool ana (Kaiser Permanen!e) .. Angiomyolipoma Goold• Hills • Angiomyolipoma !.oog Beach - Angiomyolipoma Lope Beach llong Beach Vetemus Hgsoitall . Angiomyolipoma Los Angeles · Angiomyolipoma Mgntcrcy CTTR, February 2007 "Minutos" (Subscription A) Om:miKboula Hosoita!l - Angiomyoliporna Qaw !Hamad Medical Comoration) - Angiomyolipoma Saudi A111b1a CKing Fahad National Guan! !losmlal) - Angiom)'>lipoma Saudj Ambja Case 4 - Diagnosis: Angiomyo!ipoma, kidney T-71000, M-88600 Case 4 - References: Bah!11mi A, Schwanz MR. Ayala AG, ct a!. Concum:nt Angiom)'>lipoma and Two Oncoc)~omas in lhe Same Kidney. Ann Diagn Patltol 2007; 11(2):132-136. Roma AA, Magi-Gulluzzi C and Zhou M. OiO'em~tial Expression ofMelanocyne Markers in Myoid, Lipomatous, and Vascular Components of Renal Angiomyolipomas. Arch Po tiro/ Lab Med 2007; 131 (I): 122-125. Khan MS, Iram S, O'Brien TS, eta!. Renal Pcrivasculilr Epilheloid Ccli·Omns'. BJU 1111 2006; 98(6):1 146-1 147. Gould Rothberg BE, Grooms MC and Dhamidharka VR. Rapjd Growth ofu Kidney Angiomyolipoma After Initiation of Oral Contraceptive Therapy. Ob.ftet Gyneco/ 2006; I08(3 Pt 2):734-736. Case No. 5, Accession No. 3011 5 February 2007 Alameda (Alameda County Medical Center) - Lciomyosilreoma FontMp CK!!jtq Pennanerue) - LeiomyoS3rcorna G!jl!!3da Hjl!s - Leiomyoma Long Beach - Degenerating leiomyoma Long Bqsb CLong Beach Veterans Hpsnhal) • Leiomyoma with degenerative: changes Los Angeles .. Leiomyosarcoma Monterey (Communi tv Hospital of Moorerey Peninsula) - Leiomyoma (2); L..tiomyosurcoma (1) !2!!kh!nll - Leiomyoma sarcoma Orange CITR, Fc.bru <~ry 2007 .. Mmutes•' (Subscription A) 9 Pennsylvania rorexel Universicy College of Medicine) . J:.eiomyoma with infarction Pennsylvania (Lehigh Vallev Hospital) · Smooth muscle neoplasm favor Jaw gr.adc leiomyosarcoma Pcnnsvlvania (Magee \Vomen)s Hospital) · Mesoblastic nephroma Pennsylvanjp. CMt. NiUanv Medical Center) • Leiomyosarcoma Pennsylvania (pennsylvania Hospital Re.~; i de n tc;) · Leiomyosarcoma Puerto Rico flJniversiwofPuerto Rico) · Leiomyosarcoma South Dakota (University of South Dakota Residents) - Leiomyosarcoma Tennessee. Kingsport · Leiomyosarcoma Texas (Scott & White Memorial Hospi(!ll) - Leiomyoma Texa.<:.:. Houston . Leiomyosarcoma Texas. Lubbock .. _Lciomyos Case 5- Diagnosis: Leiomyosarcoma, kidney T-71000, M-88903 Case 5 - References: Kendal WS. The Comparative Survcval of Renal Leiomyosarcoma. Can J ()ro/2007; 14( 1):3435-3442. Sharm:1 D, Pradhan S, Aryya NC, et al. Leiomyosarcoma of Kidney. A Case Report with Long Tenn Result After Radiotherapy and Chemod1crapy. In/ Urol Nephro/2001. Kartsanis G, Douros K, Zolota V, et al. Cas<>Reporr. Leiomyosarcoma of the Renal Pelvis. Int Urol Nephro/2006; 38(2):21 1-21.3. Komi)oan"' M. A Case of Lei·omyosarcoma Involving the Renal Hilu.s. Jp11 J C/in Onco/200~; 36(2): 122. Case No. 6, AccessiOJI No. 30289 February 2007 Alameda(Aiameda County Medjcal CcD!CO - ~ful li locu l arcyst (cystic nephroma) Fontnna (Kaiser Pcnnantnte) - Mixed epithelial. srrom31t umor bfkidney Granada Hills .. Cystic nephroma Long Beach - Benign polycystic disease Long !3eacb (Long Beach Veterans Hospital) - Polycystic disease, benign Monterey (Community Hospital of'Monterev Peninsula) - Cystic nephroma Oakland - Multicystic nephroma Orange COrangc County Pathology Medical Group) - Cystic nephroma Oxnard{St. John's Regional Medical Cemer) - Multicyslic nephroma (4} San Diego - Ch.ronic pyelonephritis, spindle cell lesion leg, solitary fibrous tumt>r §;!n Djcgo @yal Medical Center San Dieao) - Cystic nephroma San Diego 10 CTTR. February 2007 "MiJiutes" (Subscri ptiQn A) Santa Rosa !Santo Rosn Mem<>rjo! Hosoita!) • Cysnc nephromn(2); Multi!oculor renal cyst (cystic nephroma, ..mlticystic nephroma") ( I) Woo41ond Hills Q Case 6 · Diagnosis: Mixed epi:hclial and stromal tumor, kidney T-71000, M-81003 Consullatjon; Stu.nfotd University, Richar Case 6 ~References: C'rrR, February 2.007 ''Minutes'' (SuburipLion A) II Bisceglia M, Oalliani CA, Senger C, et al. Renal Cystic Diseases. A Review. Adv in Anat P Case. No. 7, Accession No. 30364 February 2007 Alameda {Aiamoda Countv Medical Center) - Solitary fibrous tumor Fontana O 12 CTTR. Febtuaty 2007 "'Minutes" (SubS<: riplion A) Texas Lubboc.k - So Wary fib rous tumor Washington (Madigan Army Medical Center) - Solitary fibrous tumor {12) \Vest Virginia (Qrccnbrjer Vallev Medical Center) · Solitary fibrous tumor Australia !Royal Hobart Hospital) - Solitary fibrous tumor Australia (Royal frjnce AIired Hospital) · Solitary fibrous tumor Australia (Sullivan Nicolaides Pathology) - Solitary fibrous tumor Brazil Case 7 - Diagnosis: Solitary fibrous tumor, kidney T-71000, M-90510 Case 7 Reference..'.;: Gengler C and Guillou L. Solitary Fibrous Tumour and Naemangiopericytoma. Evolution of a Concept. Histopatho/2006; 48(1 ):63-74. Fine SW, McCarthy OM; ChanTY, et al. Malignant Solitary Fibrous Tumor of the Kidney. A Report of a Case and ComprehenSive Review of the Literature. Arch Pathol La~ Ed 2006; 136(6):857-861 . :Kohl SK, Mathews K and Baker J. Renal Hilar Mass in an 85-Year-Oid Woman. Solitary Fibrous Tumor. Arch Patho/ Lab Med 2006; 130(1):1 17-119. Yamaguchi T, Takimoio T, Yamashita T, ct al. ~at-Contain i ng Variant ofSoli tary fibrous Tumor {Lipomatous Hemangiopericytoma) Arising on Surface of Kidney. Urol2005; 65(1):175. W~ng J, Aroer DA, Fran~cl K, Cl al. Large Solitary Fibrous Tumor of the Kiditey. Report ofTwo Cases and Review()( the Literature. Am J Stu-g Pat/to/ 20~ 1 ; 25(9): 1194-1199. Case No. 8, Accession No_ 30290 February 2007 Alameda (Alameda Countv Mcdjcal Center) - Primitive ncurocctodcrrnaJ tumor Fontana Case 8 .. Diagnosis: High grade sarcoma (NOS), kidney T-71000, M-88 103 Directors Note: "Tumor has striking similarity to monophasicsy novia! sarcoma. but is keratin negative. Mole.cular studies were not done." (dre) Consuluujon: St;mford University. Anne-E. DrejeL, M.D. • 1'High Grade SHrcoma. NOS" Case 8 Referenc~: 14 C ITR, February2007 "Minutes" (Subscription,\) Dotan ZA, Tal R, Golijanin D, Snyder ME, ctal. Adull Genitourinary Sarcoma. The 25,Year Memorial Sloan-Kettering Experience. J Uro/2006; 176(5):2033-2038, Dnii'Oglio MF, Licbcrknecht M, Gouveia V, et al. Sarcomatoid Differentiation in Renal Cell Carcinoma. Prognostic Implications. lnt Braz J Urol2005; 3 1(1):10-16. Deyrup AT, Montgomery E and Fisher·C . Leiomyosarcoma of the Kidney. A Clinicopathologic Swdy. Am J Surg Patlro/2004; 28(2): 178-182. Chen PC, Chang YH, Yen CC, et aJ. Primary Renal Synovial' Sarcoma with Inferior Vena Cava and Right An·ium Jnvasion. ltrt.l Uro/2003; 10(12):657-660. Case No. 9, Accession No. 30185 February 2007 A1amcd!l (Alameda County Medjcal Cemer) - Renal cell carcinoma Fontana £Kaiser Permanente) - Rena) cell carcinoma, chromophobe type Granada HillS - Oncocytoma Long Beach .. Oncocytoma l,smg Beach (Long Beach Ve.terans Hospital) ~ Oncocytic neoplasm, favor oncocytoma Los Angeles • Oncocytoma Monterey (Community Hosnital of Monterey Pe'ninsula) · 'Papillary renal cell carcinoma Oakland - Oncocytoma Orange (Orange County Pathology Medical Groun) - Oncocytoma Oxnard 1St John's Regional Medical Center) · Renal cell carcinoma (4) San Diego - Oncoc}1oma vs. renaJ·ceJI carc!noma San Dieqo (Naval Medical Center San Dicso) - Papillary renal cell carcinomJl San DiegO (Scripps Heahh.} - Renal cell carcinoma, .papillary type San Diego (UCSDl - Papillary renal cell carcinomJl, typo 2 San FQ)nd~eo CSan Fr3nC.isco General Hospital) • Eosinophilic chromophobe renal carcinoma Santa Barbara • Oncocytoma Santa Rosa (Santa Rosa Memorial Hosoiml) - o ncocytoma (3) Woodland Hills (Kaiser Pcrmanente) - Oncocytoma Woodland Hills (Suda's Soldiers) - Oncocytoma . Arkansas (Un jycrsjty of Ark AOSB5: for Medical Scien ce.~) • Oncocytoma. kidney Georgia Decatur .. Tubulocystic. carcinoid Wjnojs, Burr Ridge - Papillary carcinoma (2) Illinois ClTR, FebnJBI)' 20.07 ''Minu!cs" (Subscri ptjon A) t; Australia (Roval Hobart Hospital) - Papillary renal cell carcinoma, cype-2 Australia IRowl Prince Alfred Hospitall - Papillary renal cell carcinoma Austrnlia !Sullivan Nicolaides Pathology) - Renal oncocytoma Brnzil Ireland CKerry-General Hospital) .. Papillary rena] cell carcinoma1 type 2 Jamaica IThc University of We§llndjes) - Papillary renal cell carcinoma Japan Case 9-Diagnosis: Renal cell carcinoma with papillary and tubulocystjc features, kidney T-71000, M-83123 Case 9 - Refc·renccs: Mizutaoi Y, Nakanisbl H, Li YN,.et al. Overexpression ofXIAP Expression in Renal Cell Carcinoma Predicts a Worse Prognosis. In~ J Oncol 2007; 30(4}:919-925 . Antonelli A, Cozzoli A, Zani D, et al. The Follow-Up Management of Non-Metastatic Renal Cell Carcinoma. Definition ofa Surveillance ProtocoL BJU lnt 2007; 99(2):296-300. Maclennan GT and Bostwick DG. Tubulocysric Carcinoma, Mucinous Tubular and Spindle Cell Carcinoma aod Other Recently Described Rare Renal Tumors. Clrn i" Lab Med 2005; 25(2):393-4 I 6. Case No. 10, Accession No. 30233 February 2007 Alameda (Alameda County Medical Ccnt<;r) - Colle<:ting duct carcinoma Eo!)!nna (Kajser Permanence) ~ Mucinous tubular and spindle cell carcinoma of kidney Granada Hills • Collecting duct carcinoma Long Beach . (nvasive urotheliaJ carcinoma, high grade Long Beach t6 CrrR, Februat}' 2007 "Minutes" (Subscription A) Nebraska (Creighton University School ofMcshcinc) • Collecting duct carcinoma New Mexico CUniversjtv of New Mexico) . Carcinoma of the collecting ductS of'Bcllinl New York <(,ong lslnpd Jewish Medical Ccmer) • Carcinoma of the collecting duct of Bellini New York Cnsr 10. Diagnosis; Collecting duct carcinoma, kidney T-71000,~·83123 Case I 0 - References: Swartz MA, K:uth ], Schneider DT, et al. Renal Medu!!nryCan:moma. Clinical, Patboloaic, Immunohistochemical ond Genetic Analysis with Pathogenetic Implications. Uro/2002; 60(()):1083-1 089. Steele ELand MacLenll31\ GT. Renal Medullary Carcinoma. J ofUro/2005; 174(4 Pt 1): 1449. Assad L, Rcsctkow E, Olivcirn Vl, ct•!. Cytologic Features of Renal Medullary Carcinoma Olncer 200S; lOS( I ):28-34. Vargos-Gon:w.lcz R, Sotclo-A vila C and Corin AS. Renal Medullary Carcinoma In A SiX· Year-Old Boy with Sickle Cell Trun. PtJJhol Oncol Res 2003; 9(3): 193·195. Pe)'\'omaure M, Thiounn N, Scotte F, ct of. Collecting Duct Carcinoma of the Kidney. A Clinicopathological Study of9 Case.. J of Uro/2003; I 70(4 Pt I): 1138-1140. Polascik TJ, Bostwick DG and Cairns P. Molecular Genetics and Histopathologic Fcatur~s of Adult Distal Nephron Tumors. Urol 2002; 60(6):941-946 . • C11'R, Febtuary 2007 "M'inute~ .. (Subscription A) 11