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DED UN 18 O 98 F N Y O T R E I T H C E N O A E S S S L T A E A C R C I N S M S E E H C C TI N O CA September 2008 Vol. LXXXVII, No. 1 N • AMERI September Meeting NESACS Members Medicinal Chemistry Symposium at Boston College Honored at NERM “New Developments in Anti-Infective Research” Book Review Interviewing in the “A Scientist's Guide to Talking with the Media” Bio-Pharma Industry Reviewed by Dennis J. Sardella Part 4 - “The Offer Stage” by Megan Driscoll 2 The Nucleus Summer 2008 The Northeastern Section of the American Chemical Society, Inc. Contents Office: Marilou Cashman, 23 Cottage St., Natick, MA 01360. 1-800-872-2054 Announcements 4,6 (Voice or FAX) or 508-653-6329. ______________________________________ e-mail: mcash0953(at)aol.com Gustavus J. Esselen Award Nominations, ACS Northeast Regional Any Section business may be conducted via the business office above. Undergraduate Day, Grants-in-Aid to Undergraduates, Call for Papers for NESACS Homepage: UndergraduateResearch Poster Session, NSYCC September Activities http:/ /www.NESACS.org Monthly Meeting 5 David Cunningham , Webmaster _______________________________________ ACS Hotline, Washington, D.C.: Joint with the Medicinal Chemistry Section, A Symposium on "New 1-800-227-5558 Developments in Anti-Infective Research " at Boston College Officers 2008 Preliminary Annoucements 6,7 Chair: _____________________________ Marietta Schwartz Chemistry Department, UMASS-Boston NSYCC/NESACS-JCF/GDCh Exchange to Germany, Boston, MA 02125 Connections to Chemistry 2008 617-287-6146; marietta.schwartz(at)umb.edu National Chemistry Week Events 9 Chair-Elect: __________________________ Dr. E. Joseph Billo Book Review 10 13 Shattuck Street _________________________________________ Natick, MA 01760 A Scientist's Guide to Talking with the Media. Practical Advice from the 508-653-3074, joseph.billo(at)verizon.net Union of Concerned Scientists. Reviewed by Dennis J. Sardella Immediate Past Chair: Mukund Chorghade Directions to the September Meeting 11 14 Carlson Circle, Natick, MA 01360 _____________________ 508-651-7809 and 308-3891 2008 Esselen Award Photos 11 Chorghade(at)comcast.net ____________________________ Secretary: The Catalyst Program 12 Michael Singer __________________________________ Sigma-Aldrich Two NESACS Members Honored at NERM 13 3 Strathmore Rd., Natick, MA 01360 __________________ 508-651-8151X291; msinger(at)sial.com Article and Photos by Morton Z. Hoffman Treasurer: September Historical Events in Chemistry 14 James Piper _________________ 19 Mill Rd., Harvard, MA 01451 By Leopold May, Catholic University of America 978-456-3155, piper28(at)attglobal.net Interviewing in the Bio-Pharmaceutical Industry 18 Auditor: _____________ Anthony Rosner Part 4-The Offer Stage by Megan Driscoll Archivist: Cover: Myron S. Simon Marietta Schwartz (University of Massachusetts Boston), NESACS 20 Somerset Rd. Newton, MA 02465; 617-332-5273 Chair, with Dennis Dougherty (California Institute of Technology), winner of the Romysimon(at)mindspring.com 2008 James Flack Norris Award in Physical Organic Chemistry sponsored by the Trustees: ACS Northeastern Section. (Photo courtesy of Morton Z. Hoffman) Joseph A. Lima, Esther A. H. Hopkins, Deadlines: Michael E. Strem November 2008 Issue: September 15, 2008 Councilors Alternate Councilors Term Ends 12/31/2008 December 2008 Issue: October 13, 2008 Doris I. Lewis Patrick M. Gordon Morton Z. Hoffman Michael P. Filosa Christine Jaworek-Lopes Lawrence Scott Mary Burgess Liming Shao Donald O. Rickter S.B. Rajur Term Ends 12/31/2009 The Nucleus is published monthly, except June and August by the Northeastern Section of the American Catherine Costello Julia H.Miwa Chemical Society, Inc. Forms close for advertising on the 1st of the month of the preceding issue. Text Patricia Mabrouk Alfred Viola Michaeline F. Chen Jerry P. Jasinski must be received by the editor six weeks before the date of issue. Dorothy J. Phillips Eva B. Binnun Editor: Michael P. Filosa, Ph.D., ZINK Imaging, Inc., 16 Crosby Drive, Building 4G, Amy Tapper Barney Grubbs Bedford, MA 01730 Email: Michael.filosa(at)zink.com; Tel: 508-843-9070 Term Ends 12/31/2010 Associate Editors: Myron S. Simon, 20 Somerset Rd., W. Newton, MA 02465, Tel: 617- 332-5273 Thomas R. Gilbert Timothy B. Frigo Sheila E Rodman, Konarka Techologies Inc., 116 John St. Suite 12, Lowell, MA Pamela Nagafuji Mark Froimowitz 01852 email:srodman(at)konarka.com tel 978-569-1414 Robert Lichter David Cunningham Michael Singer Erik Rozners Board of Publications: Mary Mahaney (Chair), David Cunningham, Vivian K. Walworth Business Manager: Karen Piper, 19 Mill Rd., Harvard, MA 01451, Tel: 978-456-8622 All Chairs of standing Advertising Manager: Vincent J. Gale, P.O. Box 1150, Marshfield, MA 02050, Committees, the editor Tel: 781-837-0424; FAX: 781-837-1453 of THE NUCLEUS, and Contributing Editors: Morton Hoffman, Feature Editor; Dennis Sardella, Book Reviews the Trustees of Section Calendar Coordinator: Sheila Rodman, email: srodman(at)konarka.com Funds are members of the Photographers: Morton Z. Hoffman and James Phillips Board of Directors. Any Councilor of the American Chemical Society Proofreaders: Donald O. Rickter, Myron S. Simon, Vivian K. Walworth, E. Joseph Billo residing within the section area is an ex officio Webmaster: David Cunningham, webmaster(at)nesacs.org member of the Board of Directors. Copyright 2008, Northeastern Section of the American Chemical Societ y, Inc. The Nucleus Summer 2008 3 of the award will be reimbursed. The Nominations award will be presented at the April 16, Corporate Patrons ($2000+) 2009 meeting of the Section. The Abbott Bioresearch Gustavus John Esselen Award Awardee is expected to deliver an Genzyme for Chemistry in the Public address related to the work for which Lyophilization Service of New England Interest the honor is conferred. Merck Nominations shall include the National ACS The Northeastern Section (NESACS) names of two co-sponsors, a biography Novartis is inviting nominations for its presti - of the nominee, a description of the Pfizer gious Gustavus John Esselen Award work which has been recognized as Schering Corporation for Chemistry in the Public Interest. communicating the positive values of Sepracor This award is given annually to a the chemical profession, along with Serono Reproductive Institute chemical scientist, whose scientific copies of pertinent articles and popular Vertex Pharmaceuticals and technical work has contributed to news and feature articles indicative of Wyeth Pharmceuticals the public well-being and has thereby public interest. Joint nominations are communicated the positive values of Patrons ($1000-$1999) acceptable. Further information is Astra-Zeneca R&D Boston the chemical profession. The signifi - available at www.nesacs.org. cance of this work should have become Broad Institute Nominations Are Due October 15, apparent within the five years preced - Creagen Biosciences 2008. ing nomination. The awardee shall be Estate of Wallace Gleekman a living resident of the United States or Award recipients will be notified by Irix Pharmceuticals Canada at the time of the nomination. February 1, 2009. Millenium Pharmaceuticals There is no limitation to the field Nominations shall be directed to: PCI Synthesis of chemistry. The selection committee Dr. John L. Neumeyer, c/o Karen Piper Shasun USA focuses on the general public recogni - 19 Mill Rd., Harvard, MA 01451. Sirtris Pharmceuticals tion of the work, as well as its scien - In quiries may be made to John Strem Chemicals tific/technical significance. Neumeyer, Tel. (617) 855-3388; e- ZINK Imaging The Award consists of a bronze mail: neumeyer(at)mclean.harvard.edu Ziopharm Oncology, Inc. or Karen Piper: Tel. (978) 456-8622 medal and the sum of $5,000. Travel N expenses incidental to the conferring e-mail: piper28(at)attglobal.net Donors ($300-$999) Cambridge-Major Laboratories mer Research Experiences for Under - Medicilon Inc Preliminary graduates - including a panel of current Occidental and past Internship and REU partici - Organix Announcement pants; a graduate and industry fair with Peptech Corp resumé review and information about Royal Society of Chemistry SAPA-NE ACS Northeast Regional ACS career services; and a hands-on workshop highlighting interactive Undergraduate Day Green Chemistry Demonstrations Saturday, November 1, 2008 specifically designed for outreach to The Fifteenth Annual ACS Northeast high-school and middle-school stu - The event is sponsored by Regional Undergraduate Day will be dents. Participants in the workshop NESACS and is hosted by the Depart - held in celebration of National Chem - will be given an opportunity to per - ment of Chemistry at Simmons Col - istry Week on Saturday, November 1, form the demonstrations and be pro - lege and Suffolk University and the in the Park Science Center at Simmons vided with the basic materials Chemistry Physics / Liaison, the ACS College (300 The Fenway, Boston). necessary to carry out the demonstra - student Affiliates Chapter at Simmons The keynote address will be “Green tions at their home institutions. Tenta - College. Chemistry: Designing a sustainable tive demonstrations include For more info., contact Joanne future with beakers and flasks” by Dr. Cups-to-Cleaners: Hydrolysis of Poly Saro at 617-521-2720; fax: 617-521- N John Warner, President and Chief Lactic Acid Post-Consumer Waste, 3086; joanne.saro(at)simmons.edu . Technology Officer, Warner Babcock Extraction of D-Limonene from Institute for Green Chemistry, Orange