Viruses 2014, 6, 2287-2327; doi:10.3390/v6062287 OPEN ACCESS viruses ISSN 1999-4915 www.mdpi.com/journal/viruses Review Peste Des Petits Ruminants Virus Infection of Small Ruminants: A Comprehensive Review Naveen Kumar 1,* Sunil Maherchandani 2, Sudhir Kumar Kashyap 2, Shoor Vir Singh 1, Shalini Sharma 3, Kundan Kumar Chaubey 1 and Hinh Ly 4 1 Virology Laboratory, Division of Animal Health, Central Institute for Research on Goats, Makhdoom, P.O. Farah, Mathura, UP 281122, India; E-Mails:
[email protected] (S.V.S.);
[email protected] (K.K.C.) 2 Department of Veterinary Microbiology and Biotechnology, Rajasthan University of Veterinary and Animal Sciences, Bikaner, Rajasthan 334001, India; E-Mails:
[email protected] (S.M.);
[email protected] (S.K.K.) 3 Department of Veterinary Physiology and Biochemistry, Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar, Haryana 125004, India; E-Mail:
[email protected] 4 Veterinary and Biomedical Sciences Department, University of Minnesota, 1988 Fitch Ave., Ste 295, Saint Paul, MN 55108, USA; E-Mail:
[email protected] * Author to whom correspondence should be addressed; E-Mail:
[email protected]; Tel.: +91-565-2763260; Fax: +91-565-2763246. Received: 13 March 2014; in revised form: 26 May 2014 / Accepted: 28 May 2014 / Published: 6 June 2014 Abstract: Peste des petits ruminants (PPR) is caused by a Morbillivirus that belongs to the family Paramyxoviridae. PPR is an acute, highly contagious and fatal disease primarily affecting goats and sheep, whereas cattle undergo sub-clinical infection. With morbidity and mortality rates that can be as high as 90%, PPR is classified as an OIE (Office International des Epizooties)-listed disease.