DOCSLIB.ORG

Exploring Hidden Worlds October

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Exploring Hidden Worlds October EXPLORING HIDDEN WORLDS OCTOBER - NOVEMBER 2015 sheffield.ac.uk/krebsfest KREBSFEST THE WORK OF SIR HANS KREBS EXPLORING HIDDEN WORLDS Sir Hans Krebs was The KrebsFest is a celebration of the scientific awarded the Nobel Prize research of Sir Hans Krebs, winner of the Nobel Prize in Physiology or Medicine for Medicine in 1953 for his pioneering work at the in 1953 for discovering University of Sheffield. At the festival we will explore the citric acid cycle, Krebs’ legacy through a series of public events and also known as the Krebs exhibitions including talks from Nobel Prize winners. cycle, while working at the University of Sheffield. KrebsFest is open to everyone and it’s free. The cycle explains one All venues are fully accessible. of the most fundamental processes of life: the All events are subject to change. For the latest conversion of food into information, see: sheffield.ac.uk/krebsfest energy within a cell. For further information: Krebs was born in Hildesheim in northern Germany in 1900. sheffield.ac.uk/krebsfest He followed in his father’s footsteps and studied [email protected] medicine before deciding his future lay in research rather than medical practice. Krebs, who was Jewish, 0114 2220563 left Germany in 1933 after he was dismissed from his post at the University of Freiburg following Hitler’s @UniShefEngage #krebsfest rise to power. He initially worked at the University of Cambridge before he took up a post at the University of Sheffield in 1935 where he worked for 19 years. 02 03 KREBSFEST EVENTS There are lots of exciting, free events taking place during KrebsFest. Find out more about each event further in the brochure. 15 October to Winter Garden Exhibition Pages 8–9 3 November 15 October to Western Bank Exhibition Pages 18–19 early 2016 2 November to Winter Garden Activities Page 9 3 November 9 November Nobel Prize Winner Talk – Page 10 Sir Richard Roberts 13 November KrebsFest Public Night Pages 14–17 18 November Nobel Prize Winner Talk – Page 11 Professor Jules Hoffman 25 November Nobel Prize Winner Talk – Page 11 Sir Paul Nurse AN URBAN RETREAT – INSPIRED BY THE KREBS CYCLE The Krebs cycle and our relationship to the natural environment have inspired the development of proposals for the rejuvenation of the University of Sheffield garden on the corner of Durham Road and Clarkson Street. Sheffield-based artists Owen Waterhouse and David Appleyard are working with Professor Nigel Dunnett of the University’s Department of Landscape to create a garden showcasing the best in urban planting design in combination with a feature artwork that draws people to the space. The proposals are currently in development and we expect A ‘work in progress’ reveal of Dr Florence Blanchard’s to see activity on site during Autumn 2015 – check the Krebs cycle depiction – see page 14. project webpage for regular updates: sheffield.ac.uk/efm/ estatesdevelopment/projects/durhamroad 04 05 TODAY’S CUTTING EDGE RESEARCH THE GRANTHAM CENTRE The Grantham Centre for Sustainable The great legacy of Sir Hans Krebs, both for Sheffield and Futures is an ambitious and innovative the world, is in demonstrating how we can use scientific collaboration between the University methods and understanding to uncover the hidden workings of Sheffield and the Grantham of life. In 1988 the Krebs Institute was established at Foundation for the Protection of the the University of Sheffield. The Krebs Institute brings Environment. Our sustainability research together scientists to build on this legacy in understanding creates knowledge and connects it those mechanisms in biology that underpin life on earth. to policy debates on how to build a fairer world and save Molecular science research at Sheffield is embodied within natural resources for future generations. One example of three projects that describe our vision for the next 10 such research is that undertaken in the Plant Production and years: Imagine, the Grantham Centre and Florey. Protection (P3) centre where world-leading scientists are translating our basic plant and soil sciences research into practical solutions to feed the world’s expanding population. IMAGINE: IMAGING LIFE grantham.sheffield.ac.uk The University of Sheffield is establishing a world-class centre FLOREY INSTITUTE: TACKLING INFECTIOUS DISEASE developing and applying revolutionary microscope technologies, that allow Inspired by the work of Nobel Prize scientists to see the intricate inner winner Sir Howard Florey, we are workings of life in unprecedented striving to save lives by understanding detail. We are using these insights how infective bacteria (pathogens) to unravel how microbes like the MRSA bacteria grow interact with our immune system (the and evade the immune system and how solar energy is host). Sir Howard Florey was a former converted into chemical energy during photosynthesis. Chair of Pathology at the University of Sheffield. He went on to carry out the first clinical imagine-imaginglife.com trials for penicillin – a drug that saved millions of lives worldwide. Our goal is to solve major issues in infectious diseases – such as anti-microbial drug resistance – through a new, holistic approach to managing infection, that is less reliant on using antibiotics to kill the bacteria. floreyinstitute.com 06 07 This E. coli is 5 million WINTER GARDEN EXHIBITION times bigger than the real bacterium. If someone Thursday 15 October to Tuesday 3 November was standing next to the 90 Surrey Street, Sheffield S1 2LH bacteria then they would be 2000km tall and stretch With funding from the Arts Council, Dr Nate Adams from the UK to Africa! and Luke Jerram, lead artist for KrebsFest, have collaborated to translate cellular flux and biochemical ORIGAMI INSTALLATION techniques into new artistic pieces to engage the public. Luke Jerram has designed a 28-metre inflatable Seiko Kinoshita is a Japanese artist, based in Sheffield, E. coli bacteria making the nano world larger than life, who uses traditional textile techniques to create which will be dramatically suspended from the ceiling of contemporary artwork and installations. Seiko, working the Winter Garden, Sheffield and then at the University with Dr Nate Adams, has created a visual art installation of Sheffield’s Firth Hall. For KrebsFest, Luke Jerram and using the form and patterns of origami to depict the Dr Adams have taken curatorial and mentorship roles, 3D shape of the green fluorescent protein (GFP) from supporting the development of the two local artist jellyfish. GFP is integral to the cutting edge imaging commissions – Balbir Singh Dance Company (see page 15) techniques being developed in Sheffield. and Seiko Kinoshita (see page 9). ACTIVITIES INFLATABLE E. COLI Monday 2 and Tuesday 3 November, 10am–4pm Making visible the microscopic world around us, this artwork was made to contemplate and consider ATOM-LABS: MACHINES IN MINIATURE the importance of bacteria in our lives. What makes jellyfish glow in the depths of the ocean? What makes egg-whites scary to germs? Although some forms of E. coli bacteria can cause illness Visit the Atom-Labs stand and find out! and even death in humans, the use of the bacteria is vital in medical research. Described as the workhorse of MAKE A BUG biomedicine, E. coli are used by scientists to replicate Inspired by the giant E. coli, young children can make DNA. One of the first useful applications of recombinant their own bug using craft materials with expert input DNA technology was the manipulation of E. coli to from scientists. produce human insulin. 08 09 PROFESSOR JULES HOFFMANN, UNIVERSITY OF NOBEL PRIZE WINNER TALKS STRASBOURG INSTITUTE FOR ADVANCED STUDY THE INNATE IMMUNE RESPONSE: FROM INSECTS TO HUMANS Come and hear three Nobel prize-winners talk about Wednesday 18 November, 6pm incredible scientific discoveries that shape our lives. Awarded the Nobel Prize in Physiology or Medicine in 2011. Book your place at sheffield.ac.uk/krebsfest Insects are a formidable zoological group: they represent an estimated 80% of existing species and put one-third All talks take place in: Firth Hall, Firth Court, of humanity at risk of severe morbidity or deaths through University of Sheffield, Western Bank, S10 2TN their ability to transmit various types of microbes. For a long time, insects have been known to be particularly resistant to infection. Professor Jules Hoffman will discuss his research into the mechanisms underlying this resistance and share results on the unexpected similarities which exist between immune defences in insects and innate immune reactions in mammals. SIR PAUL NURSE, PRESIDENT OF THE ROYAL SOCIETY SIR RICHARD ROBERTS, NEW ENGLAND BIOLABS GREAT IDEAS OF BIOLOGY A CRIME AGAINST HUMANITY Wednesday 25 November, 6pm Monday 9 November, 6pm Awarded the Nobel Prize in Physiology or Medicine in 2001. Awarded the Nobel Prize in Physiology or Medicine in 1993. Three of the great ideas of biology are the gene theory, European non-governmental organisations and politicians the theory of evolution by natural selection, and the have declared that genetically modified organisms (GMOs) are proposal that the cell is the fundamental unit of all life. dangerous despite all scientific evidence to the contrary. When considering the question of ‘what is life?’ these This has led to bans on research on one of the most ideas come together. The special way cells reproduce promising technologies able to solve the world’s food and provides the conditions by which natural selection takes nutrition problems. While Europe doesn’t need GMOs “yet”, place allowing living organisms to evolve. A fourth idea the developing world needs them desperately. One example is is that the organisation of chemistry within the cell Golden Rice, which could be a major player to fight Vitamin A provides explanations for life’s phenomena. A new idea deficiency. Millions of children suffer and die because of this is the central role that information management plays deficiency.
Load more

Recommended publications
  • 書 名 等 発行年 出版社 受賞年 備考 N1 Ueber Das Zustandekommen Der
    書 名 等 発行年 出版社 受賞年 備考 Ueber das Zustandekommen der Diphtherie-immunitat und der Tetanus-Immunitat bei thieren / Emil Adolf N1 1890 Georg thieme 1901 von Behring N2 Diphtherie und tetanus immunitaet / Emil Adolf von Behring und Kitasato 19-- [Akitomo Matsuki] 1901 Malarial fever its cause, prevention and treatment containing full details for the use of travellers, University press of N3 1902 1902 sportsmen, soldiers, and residents in malarious places / by Ronald Ross liverpool Ueber die Anwendung von concentrirten chemischen Lichtstrahlen in der Medicin / von Prof. Dr. Niels N4 1899 F.C.W.Vogel 1903 Ryberg Finsen Mit 4 Abbildungen und 2 Tafeln Twenty-five years of objective study of the higher nervous activity (behaviour) of animals / Ivan N5 Petrovitch Pavlov ; translated and edited by W. Horsley Gantt ; with the collaboration of G. Volborth ; and c1928 International Publishing 1904 an introduction by Walter B. Cannon Conditioned reflexes : an investigation of the physiological activity of the cerebral cortex / by Ivan Oxford University N6 1927 1904 Petrovitch Pavlov ; translated and edited by G.V. Anrep Press N7 Die Ätiologie und die Bekämpfung der Tuberkulose / Robert Koch ; eingeleitet von M. Kirchner 1912 J.A.Barth 1905 N8 Neue Darstellung vom histologischen Bau des Centralnervensystems / von Santiago Ramón y Cajal 1893 Veit 1906 Traité des fiévres palustres : avec la description des microbes du paludisme / par Charles Louis Alphonse N9 1884 Octave Doin 1907 Laveran N10 Embryologie des Scorpions / von Ilya Ilyich Mechnikov 1870 Wilhelm Engelmann 1908 Immunität bei Infektionskrankheiten / Ilya Ilyich Mechnikov ; einzig autorisierte übersetzung von Julius N11 1902 Gustav Fischer 1908 Meyer Die experimentelle Chemotherapie der Spirillosen : Syphilis, Rückfallfieber, Hühnerspirillose, Frambösie / N12 1910 J.Springer 1908 von Paul Ehrlich und S.
    [Show full text]
  • Fleming Vs. Florey: It All Comes Down to the Mold Kristin Hess La Salle University
    The Histories Volume 2 | Issue 1 Article 3 Fleming vs. Florey: It All Comes Down to the Mold Kristin Hess La Salle University Follow this and additional works at: https://digitalcommons.lasalle.edu/the_histories Part of the History Commons Recommended Citation Hess, Kristin () "Fleming vs. Florey: It All Comes Down to the Mold," The Histories: Vol. 2 : Iss. 1 , Article 3. Available at: https://digitalcommons.lasalle.edu/the_histories/vol2/iss1/3 This Paper is brought to you for free and open access by the Scholarship at La Salle University Digital Commons. It has been accepted for inclusion in The iH stories by an authorized editor of La Salle University Digital Commons. For more information, please contact [email protected]. The Histories, Vol 2, No. 1 Page 3 Fleming vs. Florey: It All Comes Down to the Mold Kristen Hess Without penicillin, the world as it is known today would not exist. Simple infections, earaches, menial operations, and diseases, like syphilis and pneumonia, would possibly all end fatally, shortening the life expectancy of the population, affecting everything from family-size and marriage to retirement plans and insurance policies. So how did this “wonder drug” come into existence and who is behind the development of penicillin? The majority of the population has heard the “Eureka!” story of Alexander Fleming and his famous petri dish with the unusual mold growth, Penicillium notatum. Very few realize that there are not only different variations of the Fleming discovery but that there are also other people who were vitally important to the development of penicillin as an effective drug.
    [Show full text]
  • Howard-Florey-Maker
    _ ....II""lle,st'Ol)' of "Ie lin ~t tlt:Mc 'c y~ successfullY to rmat. pea WIth ~ IJ&. iBfoctiOus'diseases - begins-with &bit Qf IuC AI~ PI tIlil1g, a .S 9itisb ~lientlst.notlcEid In t$!B ftJal mould.,ad l:!"eveAted growth of ~ qerms {bacterial 1., lils ~ the ~In plot 0 me story 1'I0J0IYl1l$ Sr ~pvay Qf penidll 10 ~ years la1er by arl·Aus\ 1;1 Sdetl bam t'!undred s R Y~'89D this year, H'owar~ I: fIotey and h d ~ team's ~ systttma!JQ, detalla wotk "'~ Jl 11_ fJTIed petlicilin from an 53 i[l~1Jlg o~ , nto-a life saver. ' Emma ,au fY 50 IJSOO to tm e teliladll', at t'l'wiMlstral r:Ja • U verslty's JOOf\ CtJrti[l Scbool of Moolaal Rasecll'eh (HQw FJor~ ptayed 8 c roI'a II'l the-est)bllshmflnt at itI& School god ~!lr'S1ty t In h 11M), TIll> !/O"'"_....... ot l!1te.dJ1l1II d1Haie'&."4ICh .. po.~a~1I ~ Erl'1lil"1a's.lile w~!i8Vedby penicillin irllll IIlIaod .. 1111 IIihi' 1111\1:_ tva ~ntil>iol~; 8uI1hft;e phDl Cl(a pauilftl n Get'rJ1art refiJg g mp. tt WQf1d War II. ,1<42 -"ow ho"; b.d thlnP COIH~. Pft_ 1 lind Imagine hO\ she fett any years later. 2 ~ '1M .III~ !It II YOUl1'llll1J1 willi _I J."..,tllltw...... OlIl1dltlicln ,..,_by the tt.iituI t cooid~ blITlping iHlo mtJY wh fa lIay ..fI...boiIJg IIlven penldll" {JItIiJID 3" _ hIld ~ woriled- the man who made tile shown .~"in.IH",p"'-.ntIIIf tbll JIIII!Ilt dllly g~pIy mpooicillin ~bte.
    [Show full text]
  • Sir Howard Florey - Biography
    Sir Howard Florey - Biography Sir Howard Florey – Biography The Nobel Prize in Physiology or Medicine Sir Howard Walter Florey was 1945 born on September 24, 1898, at Presentation Speech Adelaide, South Australia, the son Educational of Joseph and Bertha Mary Florey. His early education was at St. Sir Alexander Fleming Peter's Collegiate School, Adelaide, Biography Nobel Lecture following which he went on to Banquet Speech Adelaide University where he Documentary graduated M.B., B.S. in 1921. He Other Resources was awarded a Rhodes Scholarship to Magdalen College, Oxford, Ernst B. Chain leading to the degrees of B.Sc. and Biography M.A. (1924). He then went to Nobel Lecture Cambridge as a John Lucas Walker Banquet Speech Student. In 1925 he visited the United States on a Rockefeller Other Resources Travelling Fellowship for a year, returning in 1926 to a Fellowship at Gonville and Caius College, Cambridge, receiving Sir Howard Florey here his Ph.D. in 1927. He also held at this time the Freedom Biography Research Fellowship at the London Hospital. In 1927 he was Nobel Lecture appointed Huddersfield Lecturer in Special Pathology at Banquet Speech Cambridge. In 1931 he succeeded to the Joseph Hunter Chair of Pathology at the University of Sheffield. 1944 1946 Leaving Sheffield in 1935 he became Professor of Pathology and a Fellow of Lincoln College, Oxford. He was made an The 1945 Prize in: Physics Honorary Fellow of Gonville and Caius College, Cambridge in Chemistry 1946 and an Honorary Fellow of Magdalen College, Oxford in Physiology or Medicine 1952. In 1962 he was made Provost of The Queen's College, Literature Oxford.
    [Show full text]
  • Penicillin: World War II Infections and Howard Florey
    In Focus Penicillin: World War II infections and Howard Florey The results were dramatic – the control mice rapidly succumbed, while all of the treated mice survived. These results attracted great interest from the scientific and military communities because, if Ian Gust replicated in humans, the drug had the potential to influence the Department of Microbiology and outcome of WWII. Immunology University of Melbourne It took Florey and 16 colleagues several months to produce suffi- Parkville, Vic. 3010, Australia Tel: +61 3 8344 3963 cient material to treat a handful of patients. The team worked under Fax: +61 3 8344 6552 fi fi Email: [email protected] dif cult circumstances with a lack of funding and equipment; at rst penicillin was made using old dairy equipment. Hospital bedpans were later used to grow the mould and the liquid containing fi Howard Florey is celebrated for his major contributions to penicillin drained from beneath the growing mould and ltered the large-scale production of the fungal product, penicillin, through parachute silk. during World War II (WWII), leading to life-saving outcomes The first patient they treated was a policeman, in whom an infected for many more than those with war wounds. scratch had developed into a life threatening infection. He was given Howard Florey was born in South Australia in 1898. After studying penicillin, and within a day began to recover. Unfortunately Florey’s medicine at the University of Adelaide he was awarded a Rhodes team only had sufficient drug for 5 days of treatment and when Scholarship to work in Oxford under Sir Charles Sherrington.
    [Show full text]
  • Illustrations from the Wellcome Institute Library the Chain Papers*
    Medical History, 1983, 27:434-435 ILLUSTRATIONS FROM THE WELLCOME INSTITUTE LIBRARY THE CHAIN PAPERS* THE three men who shared the Nobel Prize in October 1945 for their work on penicillin could scarcely have differed more in their backgrounds and characters. Fleming was sixty-four years old by then; the son of a Scottish farmer, he was a retiring man, not given to conversation. By contrast, Florey, then aged forty-seven, was the son of a wealthy Australian boot and shoe manufacturer; aggressively ambitious, his achievements and intellect were later to secure him the Presidency of the Royal Society. Then there was Chain - a mere thirty-nine years old - a Jewish refugee of Russian origin, who still had major work on penicillin ahead of him; his ambition was mixed with an independence and volubility that was to lead him into conflict with the scientific/medical establishment. Fleming has been the subject of many biographies, mostly hagiographical. Florey's role in the penicillin story was recently reassessed in Gwyn Macfarlane's excellent Howard Florey. The making ofa great scientist (Oxford University Press, 1979). Sir Ernst Boris Chain died in 1979, and his biography is being written by Ronald W. Clark. This, together with future research on Chain's papers, will enable a fuller assessment to be made of the role and character of the youngest of the three scientists. The Chain papers, recently given by Lady Chain to the Contemporary Medical Archives Centre, form an extensive collection of some sixty-nine boxes, comprising material from Chain's personal and professional life.
    [Show full text]
  • Speaker's Manuscript
    Nobel Prize Lessons 2018 Speaker’s manuscript – the 2018 Medicine Prize The Nobel Prize in Physiology or Medicine • The Nobel Prize in Physiology or Medicine is one of the five prizes founded by Alfred Nobel and awarded on December 10 every year. Before Alfred Nobel died on December 10, 1896, he wrote in his will that the largest part of his fortune should be placed in a fund. The yearly interest on this fund would pay for a prize given to “those who, during the preceding year, shall have conferred the greatest benefit to humankind.” Who is rewarded with the Medicine Prize? • The Nobel Prize in Physiology or Medicine is thus awarded to people who have either made a discovery about how organisms work or have helped find a cure for a disease. • This is May-Britt Moser, 2014 Nobel Laureate in Medicine. In 2005 she and Edvard Moser discovered a type of cell in the brain that is important for determining one's position. They also found that those cells cooperate with different nerve cells in the brain that help us to navigate. You can say that the Laureates discovered and explained a kind of GPS system in the brain. • Other Medicine Laureates include: • Francis Crick, James Watson and Maurice Wilkins, who received the 1962 Prize for their discoveries and descriptions about the structure of DNA molecules. • Alexander Fleming, Ernst Chain and Howard Florey, who received the 1945 Prize for the discovery of penicillin and its curative effects on bacterial diseases. Medicine Prize 2018 • The 2018 Nobel Prize is about a new way of treating cancer.
    [Show full text]
  • All Living Organisms Are Organised Into Large Groups Called Kingdoms. Fungi Were Orig
    What are fungi and how important are they? All living organisms are organised into large groups called Kingdoms. Fungi were originally placed in the Plant Kingdom then, scientists learned that fungi were more closely related to animals than to plants. Then scientists decided that fungi were not sufficiently similar to animals to be placed in the animal kingdom and so today fungi have their own Kingdom – the Fungal Kingdom. There are thought to be around up to 3.8 million species of fungi, of which only 120,000 have been named. The fungal kingdom is largely hidden from our view and we usually only see the “fruit” of a fungus. The living body of a fungus is called a mycelium and is made up of a branching network of filaments known as hyphae. Fungal mycelia are usually hidden in a food source like wood and we only know they are there when they develop mushrooms or other fruiting bodies. Some fungi only produce microscopic fruiting bodies and we never notice them. Fungi feed by absorbing nutrients from the organic material that they live in. They digest their food before they absorb it by secreting acids and enzymes. Different fungi have evolved to live on various types of organic matter, some live on plants (Magneportha grisea – the rice blast fungus), some on animals (Trichophyton rubrum - the athlete’s foot fungus) and some even live on insects (Cordyceps australis). Helpful fungi Most of us use fungi every day without even knowing it. We eat mushrooms and Quorn, but we also prepare many other foods using fungi.
    [Show full text]
  • EDITORIAL Year's Comments for 2005
    EDITORIAL INTERNATIONAL MICROBIOLOGY (2005) 8:231-234 Year’s comments for 2005 Ricardo Guerrero Editor-in-Chief, INT. MICROBIOL. E-mail: [email protected] For several years, new sequences of microbial genomes have dogma. Conclusive evidence for a pathogenic role of H. pylori been the highlights of microbiology and a major topic of our came from trials showing that elimination of the bacterium dra- yearly comments. But sequencing has become “routine” and, at matically changed the clinical course of ulcer. This finding was the time this editorial is being written, the complete sequences confirmed by Marshall, who swallowed a broth of H. pylori and of 284 prokaryotic genomes and 40 eukaryotic genomes have soon thereafter developed gastritis, the prelude to ulcers. He been published. This allows us to focus our comments on those recovered from the disease after treatment with antibiotics. events from 2005 that have attracted the attention of both (Warren could not join him in the experiment because he already researchers and the media. These include the Nobel Prize in suffered from peptic ulcer.) Subsequently, the two investigators Physiology or Medicine, which was awarded for the discovery successfully treated other people suffering from ulcers, in the of the role of Helicobacter pylori as the causal agent of gastric process clearly identifying the bacterium as the culprit. In 1994, ulcers; the worldwide effort to fight malaria, a disease that main- H. pylori was the first bacterium, and the second infectious ly affects developing countries; and the global spread of avian organism after hepatitis B virus, to be classified as a class I car- influenza, which is becoming a panzootic.
    [Show full text]
  • Francis Crick Personal Papers
    http://oac.cdlib.org/findaid/ark:/13030/kt1k40250c No online items Francis Crick Personal Papers Special Collections & Archives, UC San Diego Special Collections & Archives, UC San Diego Copyright 2007, 2016 9500 Gilman Drive La Jolla 92093-0175 [email protected] URL: http://libraries.ucsd.edu/collections/sca/index.html Francis Crick Personal Papers MSS 0660 1 Descriptive Summary Languages: English Contributing Institution: Special Collections & Archives, UC San Diego 9500 Gilman Drive La Jolla 92093-0175 Title: Francis Crick Personal Papers Creator: Crick, Francis Identifier/Call Number: MSS 0660 Physical Description: 14.6 Linear feet(32 archives boxes, 4 card file boxes, 2 oversize folders, 4 map case folders, and digital files) Physical Description: 2.04 Gigabytes Date (inclusive): 1935-2007 Abstract: Personal papers of British scientist and Nobel Prize winner Francis Harry Compton Crick, who co-discovered the helical structure of DNA with James D. Watson. The papers document Crick's family, social and personal life from 1938 until his death in 2004, and include letters from friends and professional colleagues, family members and organizations. The papers also contain photographs of Crick and his circle; notebooks and numerous appointment books (1946-2004); writings of Crick and others; film and television projects; miscellaneous certificates and awards; materials relating to his wife, Odile Crick; and collected memorabilia. Scope and Content of Collection Personal papers of Francis Crick, the British molecular biologist, biophysicist, neuroscientist, and Nobel Prize winner who co-discovered the helical structure of DNA with James D. Watson. The papers provide a glimpse of his social life and relationships with family, friends and colleagues.
    [Show full text]
  • Aspects of Vitamin A
    Aspects of Vitamin A The Harvard community has made this article openly available. Please share how this access benefits you. Your story matters Citation Hedley-Whyte, John, and Debra Rachel Milamed. 2009. Aspects of vitamin A. Ulster Medical Journal 78(3): 171-178. Published Version http://www.ums.ac.uk/journal.html Citable link http://nrs.harvard.edu/urn-3:HUL.InstRepos:4728141 Terms of Use This article was downloaded from Harvard University’s DASH repository, and is made available under the terms and conditions applicable to Other Posted Material, as set forth at http:// nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of- use#LAA Ulster Med J 2009;78(3):171-178 Medical History Aspects of Vitamin A John Hedley-Whyte, Debra R Milamed. Accepted 22 April 2009 SUMMARY Musgrave Park Hospital in 1942 was the site of an Anglo- American Vitamin A caper. A threatened court-martial was pre-empted. Subsequently the Queen’s lecturer in Anatomy, JW Millen, who was the other lecturer to the first editor of this journal, RH Hunter, did much distinguished work. The neurological effects of Vitamin A were elucidated. Further work on cerebrospinal fluid (CSF), placenta, thalidomide and poliomyelitis led to the pre-eminence in applied anatomy and teratology of now Reader James Wilson Millen and Professors JD Boyd and WJ Hamilton, all Queen’s Medical School graduates. Training of RH Hunter, JH Biggart and JD Boyd at Johns Hopkins University profoundly influenced these seminal discoveries. The Garretts, a family of Lisburn, st th County Down origin, saved Johns Hopkins Hospital and Fig 1.
    [Show full text]
  • General Developments 1944-1986
    Chapter 3 General Developments 1944-1986 3.1 Introduction 3.2 Administrative Developments 3.3 Legal Status of the Society 3.4 General Post-War Planning 3.5 Biological Council 3.6 Anniversary Meetings 3.7 General Pattern of Ordinary Meetings 3.8 Proceedings, Agenda Papers, Bulletin 3.9 Travel Funds 3.10 Medals and Named Lectures 3.1 1 Fellowships and Scholarships 3.12 Awards Committees 3.13 The Harden Conferences 3.14 Honorary Membership 3.15 The Society’s Nobel Laureates 3.16 A Royal Charter - To Be or Not To Be? 3.17 The Chemical Society Library 3.18 Archives and the Science Museum 3.19 The Society’s Logo 3.1 Introduction As with many aspects of our national life, the years 1944- 1985 can be considered a watershed in the development of the Biochemical Society. The end of the Second World War left the Country exhausted but a spirit of optimism was in the air. Thanks to the efforts of the Honorary Officers, the Society successfully survived the War and the mood of optimism within the Society was fully justified and has lasted well after the hopes of a brave new world have long faded in other areas of human activity. Biochemistry rapidly developed into a thriving discipline and this has been maintained throughout the post-War period, although in recent years the pace has slackened somewhat mainly owing to the parsimony of recent Government policy on support of Science. This blossoming of Biochemistry in the post-War years has been one of the great scientific successes of all time and in the DEVELOPMENT 1944- 1986 37 U.K.the simultaneous expansion of the Biochemical Society has been equally impressive.
    [Show full text]