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הנדסה ביורפואית – סמינר מחלקתי 14:00 יום רביעי בשעה 28.12.2011 חדר בנין

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הנדסה ביורפואית – סמינר מחלקתי 14:00 יום רביעי בשעה 28.12.2011 חדר בנין אוניברסיטת בן - גוריון בנגב BEN-GURION UNIVERSITY OF THE NEGEV ת.ד. 653, באר שבע P.O.Box 653, BEER-SHEVA 84105, ISRAEL 84105 המחלקה להנדסה ביורפואית Department of Biomedical Engineering הפקולטה למדעי ההנדסה Faculty of Engineering Science Tel. 972-8-6479614 Fax. 972-8-6479628 סמינר מחלקתי – הנדסה ביורפואית 28.12.2011 יום רביעי בשעה 14:00 בנין 51 חדר 015 (אודיטוריום בניין הננו) NANO-BASED TARGETED THERAPIES Prof. Joseph Kost Department of Chemical Engineering, Ben-Gurion University of the Negev Nanotechnology has the potential to revolutionize cancer and other therapies. Advances in protein engineering and materials science have contributed to novel nanoscale targeting approaches that may bring new hope to patients. Several nanocarriers have been approved for clinical use. However, to date, there are only a few clinically approved nanocarriers with drugs to selectively bind and target cancer cells. Nanoparticles used as drug delivery carriers consist of different biodegradable materials such as natural or synthetic polymers, lipids, or metals. Nanoparticles are taken up by cells more efficiently than larger micromolecules and therefore, could be used as effective delivery systems. For therapeutic applications, drugs can either be integrated in the matrix of the particle or attached to the particle surface. In the presentation the drug delivery aspects of nanomedicine, the molecular mechanisms underlying the interactions of nanoparticles with cell-surface receptors, biological responses and ultrasound as a targeting tool and its effect on cellular transport would be discussed. About the Lecturer Dr. Kost received his BSc and MSc degrees in Chemical Engineering, PhD at the Department of Biomedical Engineering, all from the Technion and MBA from BGU. He is a Professor and Dean of the Faculty of Engineering Sciences at BGU. Incumbent of The Abraham and Bessie Zacks Chair in Biomedical Engineering. In 2007 was elected to the US National Academy of Engineering. .
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