Módulo 1 – Terminología Médica

Total Page:16

File Type:pdf, Size:1020Kb

Módulo 1 – Terminología Médica Catalogación en la fuente, biblioteca sede de la OPS Organización Panamericana de la Salud. Curso virtual para codificadores de información médica. Tomo 1 Washington, DC: 2017. 1. CIE-10. 2. Educación a distancia 3. Instrucción por medios virtuales. 4. América Latina. 5. Región del Caribe. 6. Sistemas de Información de Salud. 7. Red Latinoamericana y del Caribe para el Fortalecimiento de los Sis temas de Información de Salud (RELACSIS) 8. Centro Mexicano de Clasificación de Enfermedades (CEMECE). 9. Centro Argentino de Clasificación de Enfermedades (CACE). 10. Centros Colaboradores para la familia de clasificaciones internacionales de la OPS-OMS. ISBN y Clasificación e n trá mite (Esta versión tiene carácter preliminar. Se rue ga NO re p rodu ci r.) © Organización Panamericana de la Salud, 2014. Todos los derechos reservados. La Organización Panamericana de la Salud dará consideración a las solicitudes de autorización para rep rod u ci r o tradu ci r, ín te gramen te o en pa rte , alguna de sus publicaciones . Las solicitudes deberán dirigirse al Departamento de Ges�ón del Conocimiento, Bioé�ca e Inves�gación (KB R), Organización Panamericana de la Salud, Washington, D.C., EE. UU. (www.paho.org/publications /copyright-fo rms ). La Unidad de Información y Análisis de Salud (HA) del Departamento de Enfermedades Transmisibles y Análisis de Salud (CHA), 525, 23th Street. (NW) Washington, DC 20037, ([email protected]) pod rá proporcionar información sobre cambios introducidos en la obra, planes de reedición, reimpresiones y traducciones ya disponibles. Las publicaciones de la Organización Panamericana de la Salud están acogidas a la protección prevista por las disposiciones sobre reproducción de originales del Protocolo 2 de la Convención Universal sobre Derecho de Autor. Reservados todos los derechos . Las denominaciones empleadas en esta publicación y la forma en que aparecen presentados los datos que con�ene no implican, por parte de la Secretaría de la Organización Panamericana de la Salud, juicio alguno sobre la condición jurídica de países, territorios , ciudades o zonas, o de sus autoridades, ni respecto del trazado de sus fronteras o límites. La mención de determinadas sociedades mercan�les o de nombres comerciales de ciertos productos no implica que la Organización Panamericana de la Salud los apruebe o recomiende con preferencia a otros análogos. Salvo error u omisión, las denominaciones de productos patentados llevan en las publicaciones de la OPS letra inicial mayúscula. Es ta publicación con�ene la opinión colec�va de un grupo internacional de especialistas y no representa necesariamente el criterio ni las polí�cas de la Organización Panamericana de la Salud. La Organización Panamericana de la Salud ha adoptado todas las precauciones razonables para verificar la información que figura en la presente publicación, no obstante lo cual, el material publicado se distribuye sin garan�a de ningún �po, ni explícita ni implícita. El lector es responsable de la interpretación y el uso que haga de ese material, y en ningún caso la Organización Panamericana de la Salud podrá ser considerada responsable de daño alguno causado por su u�lización. Diseño gráfico: Equipo de producción y comunicación RELACSIS. 2 Contenidos Tomo 1 4 Presentación. 5 Fundamentos y características. 6 Estructura curricular. 13 Módulo 1 – Capacitación a distancia. 25 Módulo 2 – Terminología médica. Tomo 2 212 Módulo 3 - Generalidades de la Clasificación Internacional de Enfermedades (CIE) 220 Módulo 4 Estructura básica de la CIE-10 261 Módulo 5. El diagnóstico y su codificación 283 Módulo 6 Reglas y orientaciones para el registro y la codificación de la mortalidad 350 Módulo 7. Reglas y orientaciones para el registro y la codificación de la morbilidad 379 Módulo 8. Presentación estadística 395 Bibliografía 3 Presentación Este Curso ha sido desarrollado por la Red Latinoamericana y del Caribe para el Fortalecimiento de los Sistemas de Información en Salud (RELACSIS), en alianza con la Organización Panamericana de la Salud/Organización Mundial de la Salud (OPS/OMS) y MEASURE Evaluation, con el Centro Mexicano de Clasificación de Enfermedades y Centro Colaborador para la Familia de Clasificaciones Internacionales de la OMS en México (CEMECE) y con el Centro Argentino de Clasificación de Enfermedades y Centro Colaborador para la Familia de Clasificaciones Internacionales (OPS/OMS) en Argentina (CACE). El contenido conceptual, diseño y coordinación estuvo a cargo de Amanda Navarro y Adriana Orellano, con la colaboración en la edición del material de Manuel Yañez. El grupo de trabajo que elaboró la propuesta estuvo coordinado por Alejandro Giusti. Se agradece el aporte de las Dras. Martha Mazas, María López De Neira y María Laura Martínez integrantes del CACE, por la elaboración del Módulo de Terminología Médica (Módulo de estudio 2). Nuestro agradecimiento al Lic. Alejandro Giusti y a la Dra. Patricia Ruíz por el apoyo permanente en la tarea realizada. Secretariado RELACSIS Alejandro Giusti (OPS) Beatriz Plaza (MEASURE/Evaluation) Patricia Ruiz (OPS) Responsable CEMECE Aline Jiménez (DGIS, Secretaría de Salud, México) Responsable CACE Elida Marconi (DEIS, MSP, Argentina) OPS en México Tamara Mancero 4 Fundamentos y Características Los Sistemas de Información en Salud se nutren de datos de distintos componentes, que los aportan con un objetivo muy claro: la toma de decisiones y la gestión en salud. Para que a los responsables de estas actividades, se les brinden datos fidedignos, es imprescindible que todo el camino recorrido por ese dato hasta convertirse en información, tenga un tratamiento correcto por parte de los distintos actores intervinientes. O sea, que la captura y tratamiento del dato sea ajustada a la realidad, para que la información obtenida sea uniforme, comparable y oportuna. Uno de los actores de relevancia en el proceso de elaboración de la información, es quien aplica la Clasificación Estadística Internacional de Enfermedades y Problemas Relacionados con la Salud. Décima Revisión (CIE-10); es decir, el codificador de la información médica. Para ello debe capacitarse con el fin de conocerla y utilizarla correctamente. Este es el sentido del Curso Virtual de Codificación de Información Médica con la Clasificación Estadística Internacional de Enfermedades y Problemas Relacionados con la Salud. Décima Revisión (CIE-10). Características: Ha sido diseñado en la modalidad de enseñanza a distancia (E- learning), a los fines de democratizar el acceso a la capacitación y posibilitar que personas de diferentes países tengan la misma oportunidad de realizarlo. Para ello se han utilizado los aportes que la tecnología brinda, colocándolo en el Entorno Regional de la Organización Panamericana de la Salud (OPS). • Cada participante poseerá un Nombre de Usuario (propio y único) como también una Contraseña para su ingreso. • La estructura del curso es modular. En ocho (8) Módulos de Estudio, se impartirán los conocimientos para la formación integral del codificador. • Cada uno de los Módulos (dentro del Entorno Virtual), está integrado por los siguientes bloques: o Estructura: consta de una Introducción, Objetivos e Índice del Módulo. o Contenido: es el desarrollo temático del Módulo. o Guías Prácticas: contienen ejemplos que el estudiante debe resolver y consultar su respuesta. o Presentaciones en Power Point. o Videoconferencia/videos, según los casos • Tutores: nexo fundamental entre el Entorno Virtual y los participantes. Son las personas preparadas para tal fin, cuya función es la de guiar, crear técnicas para facilitar el aprendizaje, orientar en la resolución de dudas, evaluar a los estudiantes y estar en permanente contacto con ellos. • Evaluación Final: para aprobar la capacitación quienes se capacitan deberán resolverla y obtener un puntaje determinado, el que será comunicado oportunamente • Constancia de aprobación de la capacitación: Les será entregada a aquellas personas que cumplan que todos los requisitos establecidos a la finalización del Curso. 5 Estructura Curricular Módulo 1 Nociones básicas sobre educación a distancia I - Formación y Capacitación • Capacitarse a lo largo de la vida • ¿Qué es la educación a distancia? • La educación a distancia en los tiempos de internet: los aportes de la tecnología educativa • La formación de codificadores II - Aprender a distancia • ¿Cómo organizar y planificar el tiempo de estudio? III - Estructura del curso de capacitación a distancia • Modalidad a distancia • Herramientas utilizadas en la modalidad IV - El docente Módulo 2 Terminología Médica I - Introducción a la anatomofisiología y la terminología médica • Sección I: Anatomofisiología y terminología médica • Sección II: Lista de prefijos y sufijos II - Terminología médica relacionada con los capítulos de la CIE-10 Capítulo I - Ciertas enfermedades infecciosas y parasitarias (A00-B99) . Organización en la CIE-10 . Ejemplos de enfermedades infecciosas y parasitarias Capítulo II - Tumores [neoplasias] (C00-D48) . Organización en la CIE-10 . Concepto de tumor . Clasificación de los tumores . Terminología médica relacionada con los tumores Capítulo III - Enfermedades de la sangre y de los órganos hematopoyéticos y ciertos trastornos que afectan el mecanismo de la inmunidad (D50-D89) . Organización en la CIE-10 . La sangre y sus funciones . Terminología médica relacionada con la sangre y órganos hematopoyéticos . Patologías más frecuentes de la sangre, de los órganos hematopoyéticos y de los trastornos de la inmunidad Capítulo IV - Enfermedades endocrinas,
Recommended publications
  • Nomina Histologica Veterinaria, First Edition
    NOMINA HISTOLOGICA VETERINARIA Submitted by the International Committee on Veterinary Histological Nomenclature (ICVHN) to the World Association of Veterinary Anatomists Published on the website of the World Association of Veterinary Anatomists www.wava-amav.org 2017 CONTENTS Introduction i Principles of term construction in N.H.V. iii Cytologia – Cytology 1 Textus epithelialis – Epithelial tissue 10 Textus connectivus – Connective tissue 13 Sanguis et Lympha – Blood and Lymph 17 Textus muscularis – Muscle tissue 19 Textus nervosus – Nerve tissue 20 Splanchnologia – Viscera 23 Systema digestorium – Digestive system 24 Systema respiratorium – Respiratory system 32 Systema urinarium – Urinary system 35 Organa genitalia masculina – Male genital system 38 Organa genitalia feminina – Female genital system 42 Systema endocrinum – Endocrine system 45 Systema cardiovasculare et lymphaticum [Angiologia] – Cardiovascular and lymphatic system 47 Systema nervosum – Nervous system 52 Receptores sensorii et Organa sensuum – Sensory receptors and Sense organs 58 Integumentum – Integument 64 INTRODUCTION The preparations leading to the publication of the present first edition of the Nomina Histologica Veterinaria has a long history spanning more than 50 years. Under the auspices of the World Association of Veterinary Anatomists (W.A.V.A.), the International Committee on Veterinary Anatomical Nomenclature (I.C.V.A.N.) appointed in Giessen, 1965, a Subcommittee on Histology and Embryology which started a working relation with the Subcommittee on Histology of the former International Anatomical Nomenclature Committee. In Mexico City, 1971, this Subcommittee presented a document entitled Nomina Histologica Veterinaria: A Working Draft as a basis for the continued work of the newly-appointed Subcommittee on Histological Nomenclature. This resulted in the editing of the Nomina Histologica Veterinaria: A Working Draft II (Toulouse, 1974), followed by preparations for publication of a Nomina Histologica Veterinaria.
    [Show full text]
  • Nails Develop from Thickened Areas of Epidermis at the Tips of Each Digit Called Nail Fields
    Nail Biology: The Nail Apparatus Nail plate Proximal nail fold Nail matrix Nail bed Hyponychium Nail Biology: The Nail Apparatus Lies immediately above the periosteum of the distal phalanx The shape of the distal phalanx determines the shape and transverse curvature of the nail The intimate anatomic relationship between nail and bone accounts for the bone alterations in nail disorders and vice versa Nail Apparatus: Embryology Nail field develops during week 9 from the epidermis of the dorsal tip of the digit Proximal border of the nail field extends downward and proximally into the dermis to create the nail matrix primordium By week 15, the nail matrix is fully developed and starts to produce the nail plate Nails develop from thickened areas of epidermis at the tips of each digit called nail fields. Later these nail fields migrate onto the dorsal surface surrounded laterally and proximally by folds of epidermis called nail folds. Nail Func7on Protect the distal phalanx Enhance tactile discrimination Enhance ability to grasp small objects Scratching and grooming Natural weapon Aesthetic enhancement Pedal biomechanics The Nail Plate Fully keratinized structure produced throughout life Results from maturation and keratinization of the nail matrix epithelium Attachments: Lateral: lateral nail folds Proximal: proximal nail fold (covers 1/3 of the plate) Inferior: nail bed Distal: separates from underlying tissue at the hyponychium The Nail Plate Rectangular and curved in 2 axes Transverse and horizontal Smooth, although
    [Show full text]
  • Basic Biology of the Skin 3
    © Jones and Bartlett Publishers, LLC. NOT FOR SALE OR DISTRIBUTION CHAPTER Basic Biology of the Skin 3 The skin is often underestimated for its impor- Layers of the skin: tance in health and disease. As a consequence, it’s frequently understudied by chiropractic students 1. Epidermis—the outer most layer of the skin (and perhaps, under-taught by chiropractic that is divided into the following fi ve layers school faculty). It is not our intention to present a from top to bottom. These layers can be mi- comprehensive review of anatomy and physiol- croscopically identifi ed: ogy of the skin, but rather a review of the basic Stratum corneum—also known as the biology of the skin as a prerequisite to the study horny cell layer, consisting mainly of kera- of pathophysiology of skin disease and the study tinocytes (fl at squamous cells) containing of diagnosis and treatment of skin disorders and a protein known as keratin. The thick layer diseases. The following material is presented in prevents water loss and prevents the entry an easy-to-read point format, which, though brief of bacteria. The thickness can vary region- in content, is suffi cient to provide a refresher ally. For example, the stratum corneum of course to mid-level or upper-level chiropractic the hands and feet are thick as they are students and chiropractors. more prone to injury. This layer is continu- Please refer to Figure 3-1, a cross-sectional ously shed but is replaced by new cells from drawing of the skin. This represents a typical the stratum basale (basal cell layer).
    [Show full text]
  • Melanin Transfer in the Epidermis: the Pursuit of Skin Pigmentation Control Mechanisms
    International Journal of Molecular Sciences Review Melanin Transfer in the Epidermis: The Pursuit of Skin Pigmentation Control Mechanisms Hugo Moreiras † , Miguel C. Seabra and Duarte C. Barral * iNOVA4Health, CEDOC, NOVA Medical School, NMS, Universidade NOVA de Lisboa, 1169-056 Lisboa, Portugal; [email protected] (H.M.); [email protected] (M.C.S.) * Correspondence: [email protected]; Tel.: +351-218-803-102 † Present address: The Charles Institute of Dermatology, School of Medicine, University College Dublin, D04 V1W8 Dublin, Ireland. Abstract: The mechanisms by which the pigment melanin is transferred from melanocytes and processed within keratinocytes to achieve skin pigmentation remain ill-characterized. Nevertheless, several models have emerged in the past decades to explain the transfer process. Here, we review the proposed models for melanin transfer in the skin epidermis, the available evidence supporting each one, and the recent observations in favor of the exo/phagocytosis and shed vesicles models. In order to reconcile the transfer models, we propose that different mechanisms could co-exist to sustain skin pigmentation under different conditions. We also discuss the limited knowledge about melanin processing within keratinocytes. Finally, we pinpoint new questions that ought to be addressed to solve the long-lasting quest for the understanding of how basal skin pigmentation is controlled. This knowledge will allow the emergence of new strategies to treat pigmentary disorders that cause a significant socio-economic burden to patients and healthcare systems worldwide and could also have relevant cosmetic applications. Citation: Moreiras, H.; Seabra, M.C.; Keywords: melanin; melanosome; melanocore; melanocyte; keratinocyte; skin pigmentation; Barral, D.C.
    [Show full text]
  • PKCΗ Promotes a Proliferation to Differentiation Switch In
    Citation: Cell Death and Disease (2011) 2, e157; doi:10.1038/cddis.2011.40 & 2011 Macmillan Publishers Limited All rights reserved 2041-4889/11 www.nature.com/cddis PKCg promotes a proliferation to differentiation switch in keratinocytes via upregulation of p27Kip1 mRNA through suppression of JNK/c-Jun signaling under stress conditions T Hara1, M Miyazaki1, F Hakuno1, S Takahashi1 and K Chida*,1 To maintain epidermal homeostasis, the balance between keratinocyte proliferation and differentiation is tightly controlled. However, the molecular mechanisms underlying this balance remain unclear. In 3D organotypic coculture with mouse keratinocytes and fibroblasts, the thickness of stratified cell layers was prolonged, and growth arrest and terminal differentiation were delayed when PKCg-null keratinocytes were used. Re-expression of PKCg in PKCg-null keratinocytes restored stratified cell layer thickness, growth arrest and terminal differentiation. We show that in 3D cocultured PKCg-null keratinocytes, p27Kip1 mRNA was downregulated, whereas JNK/c-Jun signaling was enhanced. Furthermore, inhibition of JNK/c-Jun signaling in PKCg- null keratinocytes led to upregulation of p27Kip1 mRNA, and to thinner stratified cell layers. Collectively, our findings indicate that PKCg upregulates p27Kip1 mRNA through suppression of JNK/c-Jun signaling. This results in promoting a proliferation to differentiation switch in keratinocytes. Cell Death and Disease (2011) 2, e157; doi:10.1038/cddis.2011.40; published online 19 May 2011 Subject Category: Cancer The epidermis is a stratified squamous epithelium consisting treatment and during re-epithelialization after skin injury.12 of a basal layer, a suprabasal layer, a granular layer and a Furthermore, PKCZ-null mice are susceptible to tumor stratum corneum.1 The keratinocytes in the basal layer have formation via a two-stage skin carcinogenesis protocol; a proliferative potential and are undifferentiated.
    [Show full text]
  • Chapter 6 – the Integumentary System
    Chapter 6 – The Integumentary System I. The Skin and Subcutaneous Tissue: The skin is the body’s largest organ, accounting for 15% of the body weight of adults. Please see the terms for Figure 6.1 on page ________. Be sure to recognize the picture for your exam. The skin consists of two layers: Epidermis (outer layer made of stratified squamous epithelium) and dermis (deeper layer made of connective tissue). Hypodermis is a layer of subcutaneous fat that lies below the two layers of the skin. Skin is classified as thick or thin based on the relative thickness of the epidermis. Thick skin covers the palms, soles, and surfaces of the fingers and toes. It has a thick stratum corneum, a layer of dead cells. Thick skin has sweat glands, but no hair follicles or sebaceous (oil) glands. Thin skin has a thin stratum corneum and possesses sweat glands, hair follicles, and sebaceous glands. A. Functions of the Skin 1. Resistance to trauma and infection – epidermal cells contain a tough protein called keratin that gives the skin durability. Also, skin is usually dry and slightly acidic to protect the body from bacteria & fungal infections. 2. Other barrier functions – it keeps out excess water and keeps the body from losing excess water. The epidermis also blocks harmful UV (ultraviolet) rays, thereby keeping cancer-causing radiation from deeper tissues. The skin keeps out harmful chemicals, but is permeable to several drugs and poisons. 3. Vitamin D synthesis – Vitamin D is needed for bone development and maintenance. 4. Sensation – The skin is equipped with many nerve endings that react to heat, cold, touch, texture, pressure, vibration and tissue injury.
    [Show full text]
  • Intro/Anatomy of Skin, Hair and Nails
    - Stratum spinosum 1 – Intro/Anatomy of o Superficial to stratum basale, named for spiny- appearing desmosomes between cells o Keratins 1 and 10 are expressed in this layer and are skin, hair and nails mutated in epidermolytic hyperkeratosis (aka bullous congenital ichthyosiform erythroderma) Vital Functions - Stratum basale o Located just above the basement membrane, is - Sensation, barrier, immune surveillance, UV protection, composed of 10% stem cells thermoregulation o Keratins 5 and 14 are expressed in the basal layer Fun facts and are mutated in patients with epidermolysis bullosa simplex (EBS) - The skin is the largest human organ, 15% of a person’s body weight Major CELL TYPES of the epidermis - Skin cancer = most common cancer worldwide; affects 1 in 5 1. Keratinocytes people (KC) (“squamous cells”, “epidermal cells”) o Make up most of epidermis, produce keratin - Our skin is constantly being renewed, with the epidermis 2. Melanocytes (MC) turning over q40-56 days, results in average person shedding o Neural-crest derived 9 lbs of skin yearly o Normally present in ratio of 1 MC : 10 KC’s Skin thickness varies based on…. o Synthesize and secrete pigment granules called melanosomes - Location: epidermis is thickest on palms/soles at ~ 1.5mm o *** Different races and skin types actually have the (thickness of a penny), thinnest on eyelid/postauricular at ~ same amount of melanoCYTES but differ in the 0.05mm (paper) number, size, type, and distribution of - Age: Skin is relatively thin in children, thickens up until our melanoSOMES, with fairer skin types having more 30’s or 40’s, and then thins out thereafter.
    [Show full text]
  • Structure and Function of the Skin
    2 Structure and Function of the Skin Skin disease illustrates structure and function. Loss of or Chapter Contents defects in skin structure impair skin function. Skin dis­ ease is discussed in more detail in the other chapters. ● Epidermis ● Structure ● Other Cellular Components EPIDERMIS ● Dermal–Epidermal Junction – The Basement Membrane Zone ● Dermis ● Skin Appendages Key Points ● Subcutaneous Fat 1. Keratinocytes are the principal cell of the epidermis 2. Layers in ascending order: basal cell, stratum spinosum, stratum granulosum, stratum corneum 3. Basal cells are undifferentiated, proliferating cells Key Points 4. Stratum spinosum contains keratinocytes connected by desmosomes 1. The major function of the skin is as a barrier to maintain 5. Keratohyalin granules are seen in the stratum granulosum internal homeostasis 6. Stratum corneum is the major physical barrier 2. The epidermis is the major barrier of the skin 7. The number and size of melanosomes, not melanocytes, determine skin color 8. Langerhans cells are derived from bone marrow and are the skin’s first line of immunologic defense ABSTRACT 9. The basement membrane zone is the substrate for attach- ment of the epidermis to the dermis The skin is a large organ, weighing an average of 4 kg and 10. The four major ultrastructural regions of the basement covering an area of 2 m2. Its major function is to act as membrane zone include the hemidesmosomal plaque of a barrier against an inhospitable environment – to pro­ the basal keratinocyte, lamina lucida, lamina densa, and tect the body from the influences of the outside world. anchoring fibrils located in the sublamina densa region of The importance of the skin is well illustrated by the high the papillary dermis mortality rate associated with extensive loss of skin from burns.
    [Show full text]
  • Epidermal Cell Cultures As Models for Living Epidermis
    0022-202X/79/7302-0 135$02.00/0 THE JOURNAL OF INVESTIGATIVE DERMATOLOGY. 73:135-137,1979 Vol. 73. No.2 Copyright © 1979 by The Williams & Wilkins Co. Prinled in U.S.A. REVIEW ARTICLE Epidermal Cell Cultures as Models for Living Epidermis MICHEL PRUNIERAS, M.D. Head, Laboratory on Human Shin Tumors, Fondation Adolphe de Rothschild, Paris, France, a.nd "Directeur de Recherche" a.t the French National Institute of Health and Medical Research (INSERM) The epidermis is composed of closely packed cells with after wounding and, here again the question is to see if very little intercellular matrix. Most of epidermal cells regeneration can be studied in culture. are keratinocytes which synthesize keratin and are eventually lost by desquamation. This loss is compen­ EPIDERMAL CELL CULTURE MODELS FOR THE sated by permanent proliferation of basal cells so that BIOLOGY OF KERATINOCYTES the biology of living epidermis is dominated by keratin­ An important point was made in 1960 [1] when it was shown ization and regulation of growth. Mainly 2 mechanisms that adult guinea pig epidermal cells would grow in culture, have been proposed for this regulation. The first is based after complete elimination of dermal connective tissue. It was on the fact that the epidermis is always in contact with shown thereafter, that not only growth, as evidenced by mitotic the underlying dermis. The idea is that growth as well activity, but also differentiation, as demonstrated by multilay­ as keratinization are controlled by connective tissue ering, tonoftiament formation, desmosome reconstruction and factors passing through the basement membrane.
    [Show full text]
  • Skin, Very Close Up, Is Certain to Heighten Your Appreciation of This Most Obvious' of Organs
    S~lnl Very Close Up I'm interested in how the skin works because it's the part ofmy body I'm mostfamiliar with, and I think the better I understand it, the better I can take care ofit. -Camille, 48, book publisher ntil you suffer a bad sunburn, have a close encounter Uwith a patch of poison ivy, or notice you don't quite look the way you'd like to look, you probably don't think much about your skin. If you're a runner, your joints are on your mind daily. If you lift weights, you visualize your muscle mass growing with each repetition. If your vision is changing, you probably fuss with decisions about your eyewear or laser eye surgery. But skin is an organ that, in the words of a retired surgeon I know, "we take for granted." Among the many reasons that we are able to take our skin for granted is the amazing reliability and durability of this important organ. Our skin weighs only about nine pounds but buttresses us against all manner of slings and arrows: sun, cold, a razor's edge, viruses, germs, and little bums. It varies in thickness with such remarkable preci­ sion that it can be flexible where needed (around the eyes, © Copyright 2000, David J. Leffell. MD. All rights reserved. 22 The Basics for example) and stiff and rigid where flexibility would be a handicap (the palms and soles). The skin on our eyelids is about half a millimeter thick (1 millimeter is about the thickness of the lead in a standard No.2 pencil).
    [Show full text]
  • Histology and Cytochemistry of Human Skin. Xiv. the Blood Supply of the Cutaneous Glands* Richard A
    View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by Elsevier - Publisher Connector HISTOLOGY AND CYTOCHEMISTRY OF HUMAN SKIN. XIV. THE BLOOD SUPPLY OF THE CUTANEOUS GLANDS* RICHARD A. ELLIS, PH.D., WILLIAM MONTAGNA, Pn.D. AND HERBERT FANGER, M.D. Although the general blood supply to the skinout clearly against a nearly colorless background. has been mapped out in some detail (1), the exactIn thick frozen sections the entire capillary plexus vascular patterns of the human cutaneous ap-surrounding the cutaneous glands can frequently pendages need clarification. Other authors havebe seen as they emerge from their parent arteriole used injection methods, silver impregnation, and(Figs. 3, 6, 8). The endothelium of the arterioles benzidine to demonstrate the blood vessels of thehas practically no alkaline phosphatase activity, skin. None of these methods is completely satis-but enzyme activity becomes increasingly strong factory or practical in all cases. We have found,near the emergence of the capillaries and is in- however, that the capillaries supplying the skintense in the final capillary loops (9). Although it and the cutaneous appendages can be easilyis difficult to positively identify the arterioles and visualized in frozen sections with the azo-dyevenules in these preparations, recent observations technic for alkaline phosphatase (Fig. 1). Thisin our laboratory on the localization of phos- method is superior to the others used. It is simple,phorylase activity in human skin make the identi- quasi-specific, and demonstrates clearly even col-fication of arterioles easy, since the smooth mus- lapsed or blocked capillaries. Using this techniccle cells around them are rich in this enzyme (Fig.
    [Show full text]
  • Skin Health and Stump Hygiene1
    Skin Health and Stump Hygiene1 GILBERT H. BARNES, M.D.2 Literally the word "hygiene" connotes a loss of its protective properties. Among indi­ state or condition of health. But adequate hy­ viduals in certain occupations, we frequently giene, or good health, of the human skin pre­ see both manifestations of such skin reaction. sents a complex problem involving much more Housewives, mechanics, laboratory workers, than a casual acquaintance with soap and and others whose work exposes certain areas water, the concept which usually comes to of the body, particularly the hands and arms, mind when hygiene is mentioned. The func­ to prolonged soaking in solutions and solvents, tional state of our human integument is pretty or even in plain water, are prone to recurrent much taken for granted by most of us. We skin irritation and breakdown. In such cases, know that this two-square-yard covering will, the chemical and physiological properties of in most cases, repair itself in event of local the skin are altered to such a degree that the injury, provided infection is avoided. Cheer­ skin's built-in protective functions are no fully we dissolve it in strong chemical solu­ longer effective. Even in the absence of pro­ tions. We broil it in the summer sun until it longed soaking, the skin may be injured locally peels off like old birch bark. We allow it to be by contact with an irritant, such as a strong rubbed and blistered in tight shoes for vanity's acid, or with a sensitizing agent, such as sake.
    [Show full text]