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Lethal Dose Table

Lethal dose (LD50) is the amount of an ingested substance that kills 50 percent of a test sample. It is expressed in mg/kg, or milligrams of substance per kilogram of body weight.

Common name Lethal doses Description Toxic response

Aspirin Acetyl- salicylic LD50 200 mg/kg Odorless white Gastric distress, confusion, psychosis, acid C9H8O4 (rat, oral) crystal stupor, ringing in ears, drowsiness, hyperventilation

Table salt Sodium chloride LD50 3 g/kg White cubic crystal Eye irritant, elevated blood pressure NaCl (rat, oral) 12357 mg/kg (human, oral) Bleach Chlorine LD50 850 mg/kg Greenish colored Corrosive to eyes, skin, respiratory (fumes) CI2 (rat, inhaled) gas, amber liquid, tract, , vomiting, pulmonary pungent odor edema

Helium Helium Not established Odorless colorless Dizziness, nausea, simple asphyxiant He gas

Lorchel mushroom Gyromitrin LD50 200 mg/kg Nausea, vomiting, severe liver C4H8N2O (rat, oral) damage, , convulsions

Arsenic Arsenic, arsenic LD50 15mg/kg Grey, metallic Acute- irritates the yes, skin, trioxide (rat, oral) crystals respiratory tract, and nausea. Chronic As, As4 O6 convulsions, tissue legions, hemorrhage, impairment

Sugar Glucose LD50 30 g/kg Sweet white powder Depressed activity, gastrointestinal C6H12O6 (rat, oral) disturbances. If diabetic- heart disease, blindness, nerve damage, kidney damage

Iron tablets Iron sulfate ~5 adult tablets toxic Grayish white Nausea, vomiting, , black FeSO4 for a 3 year old powder stool, liver damage, coma

Lead Lead Lowest published Bluish or silvery Acute –headache, insomnia, joint Pb dose 450 solid pain. Chronic-anemia, kidney (human, oral) disease, reproductive and developmental toxin.

Snake venom α-bungarotoxin Not available Large protein Paralysis, suffocation, loss of C338H529N97O105S11 molecule consciousness, seizures, hemorrhaging into tissues

Cola Caffeine LD50 140 mg/kg White odorless Acute renal failure, nausea, psychosis, C8H10N4O2 (dog, oral) powder or crystals hemorrhage, increased pulse, convulsions

Alcohol Ethanol LD50 7060 mg/kg Colorless liquid, Nausea, headache, vomiting, C2H6O (rat, oral) pleasant odor dizziness, nervous system depression, confusion, loss of consciousness

Vitamin A Retinol LD50 2000 mg/kg Yellow crystals, Convulsions, unconsciousness, C20H30O (rat, oral) orange solid reproductive toxin

Toxins © UC Regents, LHS Living by Chemistry, 2004.