Postnatal and Perinatal Trauma. Following Two Introductory
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DOCUMENT RESUME ED 047 452 EC 031 5g4 AUTHOR Angle, Carol R., Ed.; Bering, Edgar A., Jr., Pd. TITLE Physical Trauma as an Etiological Agent in Mental Retardation. INSTITUTION National Inst. of Neurological Diseases and Stroke. (DHEW) , Bethesda, Md.; Nebraska Univ., Lincoln. Coll. of Medicine. PUB DATE 70. NOTE 311p.; Proceedings of a Conference on the Etiology of Mental Retardation (Omaha, Nebraska, October 13-16, 1968) AVAILABLE FROM Superintendent of Documents, U.S. Government Printing Office, Washington, D.C. 20402 ($3.75) EDRS PRICE EDRS Price MF-$0.65 HC Not Available from EDRS. DESCRIPTORS Conference Reports, Etiology, *Exceptional Child Research, Incidence, *Infancy, *Injuries, *Medical Research, *Mental Retardation, Neurological Organization, Neurology, Pathology, Premature Infants, Prenatal Influences IDENTIFIERS Pediatrics ABSTRACT The conference on Physical Trauma as a Cause of Mental Retardation dealt with two major areas of etiological concern - postnatal and perinatal trauma. Following two introductory statements on the problem of and issues related to mental retardation (MR) after early trauma to the brain, five papers on the epidemiology of head trauma cover pathological aspects, terminal hemorrhages in the brain wall of neonates, postmortem neuropathologic findings in birth-injured patients, and epidemiological studies. Nine papers report perinatal studies on such topics as obstetric history, obstetric trauma, fetal head position, maternal pelvic size, birth position, intrapartum uterine contractions, and related fetal head compression and heart rate changes. Five special studies of the developing brain concern trauma during labor, trauma to neck vessels, the immature train's reaction to injury, partial brain removal in infant rats, and cerebral ablation in infant monkeys. The following aspects of the premature infant are discussed in relation to MR in five papers: intracranial hemorrhage, CNS damage, clinical evaluation, EEG and subsequent development, and hematologic factors. Five papers on postnatal trauma examine subdural hematoma and its etiology, the battered child, an interdisciplinary prospective study, and intellectual sequelae of coma due to acceleration concussion. (KW) I A II A A A A A A A e ADDA I , . 11) . EC031594 PHYSICAL TRAUMA AS AN ETIOLOGICAL AGENT IN MENTAL RETARDATION iv Proceedings of a Conference on the Etiology of Mental Retardation, October 13-16, 1968, Omaha, Nebraska 11%. CAROL R. ANGLE, M.D. La Department of Pediatrics University of Nebraska College of Medicine Omaha, Nebraska EDGAR A. BERING, JR., M.D. National Institute of Neurological Diseases and Stroke Bethesda, Maryland U.S. DEPARTMENT OF HEALTH, EDUCATION, AND WELFARE Public Health Service National Institute of Health National Institute of Neurological Diseases and Stroke Bethesda, Maryland 20014 1970 U.S. DEPARTMENT OF HEALTH, EDUCATION& WELFARE OFFICE OF EDUCATION THIS DOCUMENT HAS BEEN REPRODUCED EXACTLY AS RECEIVED FROM THE PERSON OR ORGANIZATION ORIGINATING Ii.POINTS OF VIEW OR OPINIONS STATED DO NOT NECESSARILY REPRESENT OFFICIAL OFFICE OF EDUCATION POSITION OR POLICY. This conference was sponsored by The National Institute of Neurological Diseases and Stroke Bethesda, Maryland and 'The College of Medicine University of Nebraska Lincoln, Nebraska For sale by the Superintendent of Documents, U.S. Government Printing Office Washington, D.C. 20402Price $3.75 3 PROGRAM PLANNING COMMITTEE Carol R. Angle, M.D., Chairman Ellsworth C. Alvord, Jr., M.D. Edgar A. Bering, Jr., M.D. Loring Chapman, Ph.D. John A. Churchill, M.D. Sherwood A. Jacobson, M.D. iii I PARTICIPANTS RAYMOND D. ADAMS, M.D., Chairman. ROBERTO CALDEYR0-BARCIA, M.D. Chief, Neurology Service Professor and Chairman, Department Massachusetts General Hospital of Physiopathology Boston, Massachusetts Hospital De Clinicas Montevideo, Uruguay ELLSWORTH C. ALVORD, JR., M.D. Professor of Pathology CoLnEvirs B. CARLSON, M.D. University of Washington Assistant Professor of Medicine and Pediatrics School of Medicine University of Washington School of Medicine Seattle, Washington Seattle, Washington GEORGE W. ANDERSON, M.D. Associate Professor of WILLIAM CAVENF.SS, M.D. Obstetrics & Gynecology Associate Director for Collaborative and Tufts University School of Medicine Field Research Boston, Massachusetts National Institute of Neurological Diseases and Stroke CAROL R. ANGLE, M.D. Bethesda, Maryland Associate Professor of Pediatrics University of Nebraska College LORING CHAPMAN, Ph.D. of Medicine Chairman, Department of Behavioral Biology Omaha, Nebraska University of California Davis, California JAMES S. APTHORP, M.D. Assistant Professor of Pediatrics JOHN A. CHURCHILL, M.D. University of Southern California Acting Head, Section on Pediatric Neurology School of Medicine Perinatal Research Branch Los Angeles, California National Institute of Neurological CHARLES F. BARLOW, M.D. Diseases and Stroke Bronson Crothers Professor of Neurology Bethesda, Maryland Harvard Medical School Boston, Massachusetts STEWART H. CLIFFORD, M.D. Project Director & Principal Investigator HEINZ W. BERENDES, M.D. The Collaborative Study at the Boston Chief, Perinatal Research Branch Hospital for Women, Lyingin Division National Institute of Neurological Associate ClinicalProfessor of Pediatrics Diseases and Stroke Emeritus Bethesda, Maryland Harvard Medical School EDGAR A. BERING, JR., M.D. Boston, Massachusetts Special Assistant to the Director for Program Analysis, National Institute of Neurological ELIZABETH B. DECKER, M.D. Diseases and Stroke Brookdale Hospital Center Bethesda, Maryland Brooklyn, New York PERRY BLACK, M.D., C.M. MURDINA M. DESMOND, M.D. Assistant Professor of Neurological Professor of Pediatrics Surgery and Psychiatry Head, Newborn Section Johns Hopkins University School of Medicine Baylor University School of Medicine Baltimore, Maryland Houston, Texas iv V PHILIP R. DODGE, M.D. RICHARD L. MASLAND, M.D. Professor of Pediatrics and Neurology Professor of Neurology and Chairman of the Head, Department of Pediatrics Department of Neurology Washington University School of Medicine College of Physicians and Surgeons St. Louis, Missouri Columbia University JAMES E. DRORBALIGH, M.D. New York City, New York Project Director & Principal Investigator Rocaut J. MEYER, M.D., M.P.H. The Collaborative Study at the Childrens Associate Professor of Pediatrics Medical Center Northwestern University School of Medicine Clinical Associate in Pediatrics Director, Infant Welfare Society Harvard Medical School Chicago, Illinois Boston, Massachusetts FRANK A. OSKI, M.D. ROBERT J. ELLINGSON, Ph.D., M.D. Associate Professor of Pediatrics Professor of Medical Psychology & Physiology University of Pennsylvania School of Nebraska Psychiatric Institute Medicine Omaha, Nebraska Philadelphia, Pennsylvania RUDOLPH ENGEL, M.D. LARRY K. PAGE, M.D. Professor of Pediatrics Associate in Neurosurgery University of Oregon Medical School Childrens Hospital Medical Center Portland, Oregon Boston, Massachusetts SANfUEL P. HICKS, M.D. WARREN H. PEARSE, M.D. Professor of Pathology Professor and Chairman The University of Michigan Medical Center Department of Obstetrics & Gynecology Ann Arbor, Michigan University of Nebraska College of Medicine EDWARD H. HON, M.D. Omaha, Nebraska Professor of Obstetrics & Gynecology EDWARD F. RABE, M.D. Yale University School of Medicine Associate Professor of Pediatrics (Neurology) New Haven, Connecticut Tufts University School of Medicine ROBERT L. ISAACSON, Ph.D. Boston, Massachusetts Professor of Psychology JOSEPH RANSOHOFF, M. D. University of Florida Professor and Chairman Gainesville, Florida Department of Neurosurgery SHERWOOD A. JACOBSON, M.D. New York University Medical Center Associate Professor of Neurosurgery New York, New York New York Medical College FREDERICK RICIIARDSON, M.D., M.R.C.P. New York, New York Associate Professor of Pediatrics ARTHUR KLING, M.D. Johns Hopkins University School of Medicine Director, Brain Research Laboratory Baltimore, Maryland Department of Psychiatry GUENTER ROSE, Ph.D. University of Illinois School of Medicine Associate Professor of Psychology and Physi- Chicago, Illinois ology SCHUYI.F.R KOHL, M.D., Ph.D. Nebraska Psychiatric Institute Professor of Obstetrics & Gynecology Omaha, Nebraska State University of New York ARTHUR L. ROSENBAUM, M.D. Downstate Medical Center S. A. Surgeon (R)(T) Brooklyn, New York Section on Pediatric Neurology NATHAN MALAMUD, M.D. Perinatal Research Branch Chief. Neuropathology Service National Institute of Neurological Langley Porter Neuropsychiatry Institute Diseases and Stroke San Francisco, California Bethesda, Maryland vi JAMES A. K. RUSSELL, M.D., F.R.C.G. ABRAHAM TOWBIN, M.D. Professor and Chairman Pathologist-Neuropathologist Department of Obstetrics and Gynaecology Danvers State Hospital University of Newcastle Ha thorne, Massachusetts Princess Mary Maternity Hospital Pathologist (Neonatology) Newcastle-upon-Tyne, England St. Margaret's Hospital Boston, Massachusetts MARIA Z. SALAM Assistant Professor of Pediatrics JACK TREMBATH, M.B., Ch.B. Department of Children's Neurology Research Assistant Professor Massachusetts General Hospital University of Nebraska College of Medicine Boston, Massachusetts Omaha, Nebraska A. EARL WALKER, M.D. S. MARK SUMI, M.D. Professor of Neurosurgery Assistant Professor of Pathology and Medicine Johns Hopkins University School of Medicine University of Washington School of Medicine Baltimore, Maryland Seattle, Washington LEE WILLERMAN, Ph.D. HANSLUKAS TEUBER, Ph.D. Research