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MGH Clinical Laboratories MGH Laboratory Handbook Online Lab Handbook: http://mghlabtest.partners.org Reference Intervals - MGH Clinical Laboratories MGH Department of Pathology 55 Fruit Street, GRJ 220 Boston, MA 02114-2696 Report generated: August 19, 2009 Test name Reference Interval Laboratory 1-25-OH Vitamin D Core lab (Sendouts) 1-3-Beta D glucan assay Core lab (Sendouts) 17-OH Progesterone Core lab (Sendouts) 25-OH Vitamin D Desired: > 32 ng/mL Core 3-Methylhistidine, urine Age matched reference range and interpretation Neurochemistry provided 5-Nucleotidase Core lab (Sendouts) A1AT deficiency profile Core lab (Sendouts) ABO/Rh Type Blood Transfusion Service Acetaminophen Negative Core Acetone Negative Core Acetylaspartate, urine Interpretation provided Neurochemistry ACTH 6-76 pg/ml Core Acylcarnitines (plasma) Core lab (Sendouts) ADAMTS13 activity/inhibitor Core lab (Sendouts) Adenosine deaminase (fluid--NOT CSF) Core lab (Sendouts) Adenovirus antibody Reported with results Microbiology Adenovirus antigen Negative Microbiology Adenylosuccinase deficiency, screen Interpretation provided Neurochemistry AFP (non-maternal specimens) Core Alanine, CSF Interpretation and age-matched reference ranges Neurochemistry provided. Wednesday, August 19, 2009 Page 1 of 26 Test name Reference Interval Laboratory Alanine, plasma Interpretation and age-matched reference ranges Neurochemistry provided. Albumin 3.1-4.3 g/dl Chelsea Healthcenter Albumin 3.3-5.0 g/dl Core Albumin (fluid--NOT CSF) Core Alcohols (ethanol, MeOH, isoprop) Negative Core Aldolase Core lab (Sendouts) Aldosterone Core lab (Sendouts) Alk Phos Adults: male: 45-115 U/L; Female: 30-100 U/L; Core <20 yrs.: 15-350 U/L Alkaline phosphatase Adults: male: 45-115 U/L Chelsea Healthcenter female: 30-100 U/L <20 yrs.: 15-350 U/L Alpha-1-antitrypsin 1 Adult normal range: 76-189 mg/dl Immunology Alpha-2-antiplasmin 80-130% activity Special Coagulation ALT (SGPT) Male: 10-55 U/L; Female: 7-30 U/L Core Aluminum Core lab (Sendouts) Amikacin (peak) Core lab (Sendouts) Amikacin (random) Core lab (Sendouts) Amikacin (trough) Core lab (Sendouts) Amino acid analysis, quantitative, amniotic fluid Reference ranges provided with results. Neurochemistry Amino acid analysis, quantitative, CSF Reported with results Neurochemistry Amino acid analysis, quantitative, fluid misc Neurochemistry Amino acid analysis, quantitative, plasma Age matched; reported with results Neurochemistry Amino acid analysis, quantitative, urine Age matched; reported with results Neurochemistry Amino acid analysis, quantitative, vitreous fluid Reference ranges provided with results. Neurochemistry Amino acid screen, urine Interpretation provided Neurochemistry Aminolevulinic acid (urine) Core lab (Sendouts) Ammonia 12-48 umol/L Core Amylase 3-100 U/L Chelsea Healthcenter Amylase (fluid--NOT CSF) Core Amylase (plasma) 3-100 U/L Core Amylase (urine) 3-460 U/L Core Wednesday, August 19, 2009 Page 2 of 26 Test name Reference Interval Laboratory ANCA Immunopathology Angiotensin converting enzyme Core lab (Sendouts) Angiotensin converting enzyme (CSF) Core lab (Sendouts) Antibody screen Blood Transfusion Service Anti-cardiolipin antibody IgG: 0-15 GPL; IgM: 0-15 MPL Special Coagulation Anti-CCP Negative <20 units (Normal);Weak Positive 20- Immunology 39 units;Moderate Positive 40-59 units;Strong Positive >60 units; Antidiuretic hormone (ADH) Core lab (Sendouts) Anti-double stranded DNA Immunology Anti-GBM antiboody Immunopathology Anti-histone antibody Core lab (Sendouts) Anti-islet cell antibody Core lab (Sendouts) Anti-Jo-1 antibody Immunology Anti-liver kidney microsomal Core lab (Sendouts) Anti-mitochondrial antibody Negative at 1:20 Immunology Anti-nuclear antibody (ANA) Negative at 1:40 and 1:160 Immunology Anti-parietal cell antibody Negative at 1:20 Immunology Antiphospholipid antibody panel Special Coagulation Anti-Ro and Anti-La antibodies Immunology Anti-Scl-70 antibody Immunology Anti-smooth muscle antibody Negative at 1:20 Immunology Antithrombin III > 6 months: 80-130% Special Coagulation Anti-thyroid antibodies (Anti-TPO) Core Anti-tissue transglutaminase IgA Core lab (Sendouts) Anti-U1RNP and anti-Smith Immunology Anti-Xa (for Fondaparinux) Special Coagulation Anti-Xa (for Fragmin) Special Coagulation Anti-Xa (for Lovenox) Special Coagulation Anti-Xa (for UF Heparin) Special Coagulation APCR (Factor V Leiden) Normal > 2.0 Special Coagulation Wednesday, August 19, 2009 Page 3 of 26 Test name Reference Interval Laboratory Arginase activity Reference ranges and interpretation provided Neurochemistry Arginine, plasma Interpretation and age-matched reference ranges Neurochemistry provided. Argininosuccinate lyase activity Reference ranges and interpretation provided Neurochemistry Argininosuccinate, amniotic fluid Normally not detectable Neurochemistry Argininosuccinate, plasma Normally not detectable Neurochemistry Arsenic (blood) Core lab (Sendouts) Arterial blood gas Acute Care Lab AST (SGOT) Adults: Male: 10-40 U/L; Female: 9-32 U/L Core Babesia (thick and thin smear) Microbiology Babesia serology Microbiology Bartonella antibody Microbiology Basic Metabolic Panel See individual tests Chelsea Healthcenter Basic metabolic panel Core Basic metabolic panel 7 Core Basic serum tox panel Core Bcr/abl gene rearrangement PCR Core lab (Sendouts) Bence Jones protein (serum) No Bence Jones protein detected in serum Immunology Bence Jones protein (urine) No Bence Jones protein detected in 50x Immunology concentrated urine Benzodiazipines (serum) Core Beta 2 microglobulin Core lab (Sendouts) Beta hydroxybutyrate Core lab (Sendouts) Beta-2-glycoprotein I antibodies Core lab (Sendouts) Bicarbonate (random urine) Core Bili direct 0-0.4 mg/dl Core Bili total Total: 0-1.0 mg/dl Core Bilirubin (direct and total) Adult: Direct: 0-0.4 mg/dl; Total: 0-1.0 mg/dl Core Bilirubin (fluid--NOT CSF) Core Bilirubin, direct 0-0.4 mg/dl Chelsea Healthcenter Bilirubin, total 0-1.0 mg/dl Chelsea Healthcenter Biopsy for immunoperoxidase staining Anatomic Pathology Wednesday, August 19, 2009 Page 4 of 26 Test name Reference Interval Laboratory BK virus PCR (urine) Core lab (Sendouts) Blood culture/sensitivity Microbiology Blood gas glucose Acute Care Lab Blood gas hemoglobin Acute Care Lab Blood gas potassium Acute Care Lab Blood gas sodium Acute Care Lab Body cavity fluids, cytology Negative Cytopathology Bone biopsy Anatomic Pathology Bone marrow biopsy/aspirate Anatomic Pathology Bone marrow iron stain Core Bone marrow MPO stain Core Bone marrow NSE stain Core Bone marrow transplant stem cell monitoring Reported with results Flow Cytomtery Bone marrow Wright stain Core Bordetella pertussis antibody Microbiology Brain biopsy Anatomic Pathology Breast biopsy Anatomic Pathology Breast cyst aspiration Negative Cytopathology Breast, smear of discharge Negative Cytopathology Bronchial brushings cytology Negative Cytopathology Bronchial wash/lavage cytology Negative Cytopathology Brucella antibody < 1:160 Microbiology Buffy coat preparation Core Buffy coats (immunopathology) Interpretation with results Immunopathology BUN Adults: 8-25 mg/dl Core BUN/Creatinine Core C- reactive protein For inflammation assessment reference range is Core < 8.0 mg/L. For cardiac risk assessment: Quintile 1, Lowest risk: <0.7 mg/L; Quintile 2, Low risk: 0.7-1.1 mg/L; Quintile 3, Moderate risk: 1.2-1.9 mg/L; Quintile 4, High risk: 2.0-3.8 mg/L; Quint C.difficile toxin assay Microbiology Wednesday, August 19, 2009 Page 5 of 26 Test name Reference Interval Laboratory C1 inhibitor (antigen) 12.4-24 mg/dl Immunology C1 inhibitor (functional) Core lab (Sendouts) C3 Adult range: 86-184 mg/dl Immunology C4 Adult range: 20-58 mg/dl Immunology Ca/Mg/PO4 Core CA-125 <35 U/ml Core CA-15-3 <30 U/ml Core CA-19-9 Core lab (Sendouts) Cadmium Core lab (Sendouts) Calcitonin Core lab (Sendouts) Calcium 8.5-10.5 mg/dl Core Calcium (24 hour urine) Up to 300 mg/24 hours Core Calcium (random urine) Core Calcium, serum 8.5-10.5 mg/dl Chelsea Healthcenter Canavans disease Core lab (Sendouts) Capillary blood gas Acute Care Lab Carbamazepine (Tegretol) Adult: 4-12 mcg/ml; <18 yrs: 8-12 mcg/ml Core Carbon dioxide 23-29 mmol/L Chelsea Healthcenter Carbon dioxide (bicarb) Adult: 23-31.9 mmol/L; Newborn: (<2 weeks): 19- Core 22 mmol/L; 2 weeks-1 year: 22-27 mmol/L Cardiac valves Anatomic Pathology Carnitine (free and total serum) Core lab (Sendouts) CBC Reported with results Chelsea Healthcenter CBC Reported with results Core CBC with Diff Reported with results Core CEA < 3.4 ng/ml Core Celiac disease panel Core lab (Sendouts) Cell count (CSF) Colorless, clear; RBC: None; WBC: 0-5/cumm Core Cell count (fluid--NOT CSF) Core Cell surface markers for hematologic malignancy Interpretation included with results. Flow Cytomtery Ceruloplasmin 27-50 mg/dl Immunology Wednesday, August 19, 2009 Page 6 of 26 Test name Reference Interval Laboratory Chimerism analysis Histocompatibility Chlamydia culture Microbiology Chlamydia nucleic acid detection Microbiology Chlamydia pneumoniae antibody Microbiology Chlamydia psittaci antibody Microbiology Chlamydia trachomatis DFA Microbiology Chloride 100 - 108 mmol/L Chelsea Healthcenter Chloride Adult: 100-108 mmol/L; < 1 year: 98-106 mmol/L Core Chloride (random urine) Core Chloride (stool) Core Cholesterol Desirable: < 200 mg/dl Chelsea Healthcenter Borderline-high: 200-239 mg/dl High: > 240 mg/dl Cholesterol (fluid--NOT CSF) Core Cholesterol (total) Desirable: < 200 mg/dl; Borderline-high: 200-239 Core mg/dl; High: > or = 240 mg/dl Chromium (blood) Core lab (Sendouts) Chromogenic
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