Diagnostica Stago, Inc. Product Catalog 2015 STA® Family of Hemostasis Analyzers

The STA® Family of MODELS: AUTOMATED STA-R Evolution® Expert Series: Automation capable, high throughput Hemostasis Analyzers STA Compact Max®: Moderate throughput provides automation of STA Satellite®: Low throughput coagulation testing MODELS: SEMI-AUTOMATED for a variety of STart® laboratory situations. FEATURES Each system performs Host-query bi-directional interface clotting, chromogenic Primary tube sampling Continuous sample access and immunoassay Open reagent system methodologies in Reagent and disposable management random access Reagent level detection QC management with Levy-Jennings mode. Because all Reagent and sample bar code reader STA® analyzers use Auto re-run and auto re-dilute options Programmable and pre-programmed options the same analysis methods Up to 70 on-board reagent capacity and the same reagent Capacity of up to 1,000 disposable cuvettes formulations, they offer Multi-constituent controls and calibrator standardization in METHODOLOGIES Clotting - VDS™ Mechanical Clot Detection the laboratory. Chromogenic - Optical density Immunological - Optical density

STA® ASSAY MENU PT APTT Fibrinogen (Clauss) D-dimer (Quantitative) Thrombin Time Reptilase Time Extrinsic Factors Intrinsic Factors Anti-Xa Activity Unfractionated Heparin (UFH) Low Molecular Weight Heparin (LMWH) Rivaroxaban* Apixaban* Edoxaban* Ecarin Chromogenic Assay (ECA-II)* Dabigatran* Antithrombin (AT) Activity Antithrombin (AT) Antigen Protein C Activity (clot-based and chromogenic) Protein S Activity Free Protein S Antigen Total Protein S Antigen VWF Antigen Plasminogen Activity Antiplasmin Activity Fibrin Monomer* Lupus Anticoagulants PTT-LA Staclot LA

*(research use only; not for use in diagnostic procedures)

2 Product Catalog 2015 Section 1 Instruments ...... 3

Section 2 Disposables & Accessories ...... 7

Section 3 Screening Tests ...... 10

Section 4 Factor Assays ...... 11

Section 5 Anticoagulants ...... 12

Section 6 Thrombophilia ...... 12

Section 7 Fibrin Formation & Degradation ...... 15

Section 8 Fibrinolysis ...... 16

Section 9 Primary Hemostasis ...... 16

Section 10 Control Plasmas...... 17

Section 11 Calibrators ...... 18

Section 12 Auxiliary Reagents ...... 18

Section 13 Quality & Compliance Solutions ...... 19

Section 14 Stago Added Value on Request (SAVOR™) ...... 20

Section 15 Thrombin Generation Research Products ...... 26

Section 16 Ecarin Chromogenic Assay (ECA) Products ...... 27

Section 17 Flow Cytometry Research Products ...... 29

Section 18 Research Kits ...... 31

Section 19 Research Components ...... 35

Abbreviations ...... 36

Table of Contents Table Terms & Conditions ...... 38

Main Index ...... 39-40

For the most up-to-date information on all our products, contact the Diagnostica Stago, Inc. Marketing Dept. at 800-222-COAG or visit our website at www.stago-us.com.

PRODUCT AVAILABILITY: Most clinical reagents are available within 5 days after receipt of order. However if a sequestered lot of reagent is required, please contact Sales Administration for availability.

For availability of research products, please contact Sales Administration at 800-222-COAG, option 3. Research products not in stock may require a 60-day notice prior to availability.

Instruments (continued) Section 1

CAT. NO. PRODUCT/ DESCRIPTION 58978 STA-R Evolution® Expert Series Hemostasis System Fully Automated, High-Throughput Hemostasis Analyzer (Automation-Capable)

58979 STA-R Evolution® Expert Series Hemostasis System with Cap Piercing Fully Automated, High-Throughput Hemostasis Analyzer (Automation-Capable)

The STA-R Evolution® Expert Series is a fully automated, hemostasis analyzer with laboratory automation connection capability. Clotting, chromogenic and immunological assays are performed simultaneously in random access mode. The system’s unique method of sample management offers high throughput and rapid processing of STAT samples without interrupting ongoing testing. Along with Stago’s exclusive method of VDS TM Mechanical Clot Detection (Viscosity-based Detection System) technology and implementation of Windows-based* software, the STA-R Evolution® Expert Series incorporates features such as QC commenting, enhanced traceability and various export formats. Analyzer is provided with: Color printer, printer stand and keyboard Uninterruptible power supply Operator’s reference manual Accessory kit 1-year warranty Dimensions • Height . . . . 49.2 inches • Width . . . . 50.3 inches • Depth . . . . 32.2 inches • Weight . . . 564 pounds

Test Selections !!"

Samples • 215 onboard sample capacity • Primary tube sampling • 5 samples per rack • Continuous sample access • True STAT management

LIS Interface Bi-directional host-query

Automation Compatible with all major automation line solutions

Reagent Menu 70 reagent positions capable of performing a complete range of routine and specialty tests. Contact your Stago Representative for the most current listing.

STA-R Evolution®

*Windows is a trademark of Microsoft Corporation. 3 Section 1 Instruments (continued)

CAT. NO. PRODUCT/ DESCRIPTION 58990 STA Compact Max® Coagulation System Fully Automated, Moderate-Throughput Hemostasis Analyzer

58989 STA Compact Max® Coagulation System Cap Piercing Model Fully Automated, Moderate-Throughput Hemostasis Analyzer

The STA Compact Max® is a fully automated, benchtop hemostasis workstation capable of performing clotting, chromogenic and immunological assays simultaneously in random access mode. The system’s unique method of sample management offers moderate throughput and rapid processing of STAT samples without the need to interrupt current testing. All sample and calibrator dilutions are performed automatically, increasing staff productivity for laboratories performing moderate-volume routine and specialty coagulation testing. The STA Compact Max® takes innovation to the next level by adding state of the art data automation with the Expert Module software. The combination of VDS methodology and the Expert Module on the STA Compact Max®#$%&%%'+

Analyzer is provided with: • Expert Module Computer and Software • 22 inch color touch screen • Laser printer • Uninterruptible power supply • Operator’s reference manual • Accessory kit • 1-year warranty

Dimensions • Height . . . . 27.75 inches • Width . . . . . 38.18 inches • Depth . . . . . 28.73 inches • Weight . . . . 309 pounds

Test Selections /!"

Samples • 96 primary sample tubes onboard: - 84 positions for primary tubes - 12 positions for pediatric tubes • Continous sample access • True STAT Management without impact on throughput #=$"

LIS Interface Bi-directional host-query or dynamic download

Reagent Menu 45 reagent positions capable of performing most routine and specialty tests. Contact your Stago Representative for the most current listing.

STA Compact Max®

4 Product Catalog 2015 Instruments (continued) Section 1

CAT. NO. PRODUCT/ DESCRIPTION 58104 STA Satellite® Hemostasis System Fully Automated, Low-Throughput Hemostasis Analyzer

The STA Satellite® is a fully automated benchtop hemostasis analyzer capable of performing clotting, chromogenic and immunological assays simultaneously in random access mode. The system enables lntegrated Health Networks to standardize patient testing results including D-dimer and Anti-Xa. The STA Satellite® offers technological advances to ensure a high level of %"%>?&@"%+

Analyzer is provided with: • Accessory Kit • Operator’s reference manual • 1-year warranty

Dimensions • Height . . . . 27.4 inches • Width . . . . 21.1 inches • Depth . . . . 25.5 inches • Weight . . . 72 pounds

Test Selections /!"

Samples • 20 onboard sample capacity • Primary tube sampling • Removable sample carousel • Continous sample loading • =$

LIS Interface Bi-directional host-query

Other Features • LED for colorimetric assays • Internal barcode reader for samples and reagents • Stago’s exclusive method of VDSTM Mechanical Clot Detection (Viscosity-based Detection System) technology

Reagent Menu • PT • APTT • Fibrinogen • AT • Liquid Anti-Xa (UFH and LMWH) • D-dimer

STA Satellite®

5 Section 1 Instruments (continued)

CAT. NO. PRODUCT/ DESCRIPTION 58230 STart® Hemostasis Analyzer Benchtop Hemostasis Analyzer for Batch Testing

The STart® is a benchtop hemostasis analyzer featuring Stago’s exclusive method of VDS™ Mechanical Clot Detection (Viscosity-based Detection System). This method eliminates interference from lipemic, icteric or other optically dense samples or reagents. The analyzer offers programmable and pre-programmed assays with curve storage, 4 independently-timed incubation stations, electronically-linked multiple pipettor, 40-character liquid crystal display and an internal thermal printer. Its lightweight, compact size makes it ideal for low to medium volume batch testing or as a back-up to an optical clot detection system.

Analyzer is provided with: • Accessory kit • Cabled pipette • Operator’s reference manual • 1-year warranty

Dimensions • Height . . . . 4.7 inches • Width . . . . . 16.1 inches • Depth . . . . . 16.5 inches • Weight . . . . 12.5 pounds

Methodology Clotting - Standard VDS® Mechanical Clot Detection

Test Selections • 17 test selections • Preprogrammed and programmable options

Other Features • Electronically-linked multiple pipettor for convenience and accuracy • Integrated printer • Four independently-timed incubation stations with audible signal • Lightweight and compact

Reagent Menu • PT • APTT • Fibrinogen • Thrombin Time • Reptilase Time • Extrinsic Factors • Intrinsic Factors • Protein C Activity • Protein S Activity • PTT-LA • Staclot® LA (Lupus Anticoagulants) • DRVV

STart®

6 Product Catalog 2015 Disposables & Accessories Section 2

CAT. NO. PRODUCT/ DESCRIPTION CONTENTS STA-R Evolution®, STA Compact® and STA Satellite® Disposables & Accessories 00741 STA®-Microtainers (for samples) 500 each 00797 STA®-Mini Reducer (5 mL vials) 100 each 00801 STA®-Maxi Reducer (10 and 15 mL vials) 100 each 00802 STA®-Microcups (for reagents) 100 each 26538 STA®-Colorimetry Box Filter (metal frame) 1 each 26555 Magnetic Ball Extractor 1 each 26674 Magnetic Red Stir Bar (C.K. Prest Only) 1 each 26699 Halogen Lamp 1 each 27307 Needle # 3 1 each 27354 Needle # 2 1 each (STA Compact®) 27420 Rear Panel Air Filters 2 each (STA Compact®) 27423 Sample Microtainer Adapter (tall) 2 each (STA Compact®) 27425 Magnetic White Stir Bar 1 each 27457 Rinsing Plate Assay Air Filter (paper ﬁ lter) 1 each (STA Compact®) 27458 Liquid Filter 1 each 27530 Teﬂ on Syringe Tip and O-Ring Kit Pack 6 each 27538 Hamilton Syringe 1 each 27543 Reduction Ring for Microcups 2 each 38125 Optical Module Fan Filter 1 each 38517 Air Filter 1 each (STA-R®) 38581 Tubing, Cap Piercing Electrovalve 1 each (STA Compact®) 38640 Liquid Cooling Glycol (Peltier System) 1 liter 38646 Needle #1 1 each (STA Compact®) 38669 STA®-Cuvettes 6 x 1000 38960 STA-R® Shuttle 1 each 39002 Aluminum Microtainer Adapters 10 each (STA-R®) 39010 Tray for 15 Racks 2 each 39011 Mapping Adjustment Cuvette 1 each 39022 Needle # 1 Cap Piercing 1 each (STA Compact®) 39134 Wheel Tube Rotation 1 each 39164 Needle # 1 Cap Piercing 1 each (STA-R®) 39249 Needle # 1 1 each (STA-R®) 39250 Needle # 2 1 each (STA-R®) 88349 V2 (Pediatric Racks) Set of 2 (STA-R®) X10034 Pediatric Tube Holder 1 each (STA-R®)

7 Section 2 Disposables & Accessories (continued)

CAT. NO. PRODUCT/ DESCRIPTION CONTENTS

STA-R Evolution®, STA Compact® and STA Satellite® Disposables & Accessories (continued) 39356 Sample Needle 1 each (STA Satellite®) 39430 STA Satellite® Cuvettes 6 x 220 (STA Satellite®) 39593 Reducer DIN 14 2 each (STA Satellite®) 39968 Microcup Adapter 2 each (STA Satellite®) 80057 Microtainer Reducer 2 each (STA Satellite®) 80132 Air Filters 3 each (STA Satellite®) 80203 Microtainer Rack 2 each (STA-R®) 80343 Soft Stylet Pack of 10

STart® Disposables & Accessories 26405 Magnetic Stir Bars (white triangular) 1 each 26441 Ball Vial (1850 / vial) 1 each 26555 Ball Extractor 1 each 26649 Thermal Paper 1 each 26729 5 mL Reduction Ring 1 each 38876 STart® Cuvettes (4 x 150) 600 / box 39476 Ball Dispenser 1 each 80109 Finnpipette 1 each 80600 Finn Tips 1.25 mL (Finnpipette Only) 100 / box 80601 Finn Tips 2.5 mL (Finnpipette Only) 100 / box 80602 Combi Tips 1.25 mL (Eppendorf Only) 100 / box 80603 Combi Tips 2.5 mL (Eppendorf Only) 100 / box

Miscellaneous Parts 26605 Reduction Ring DIN 14 (1.0 to 10 mL) 2 each 26610 Reagent Vial Reduction Ring DIN 18 (5.0 to 10 mL) 2 each 26681 Fuse 6.3 Amp Pack of 10 (STA Satellite®) 26694 Fuse 15 Amp Pack of 10 27037 Fuse 4.0 Amp Pack of 10 27575 Fuse 6.25 Amp Pack of 10 27576 Fuse 2.0 Amp Pack of 10 27578 Fuse 5.0 Amp Pack of 10 27579 Fuse 1.0 Amp Pack of 10 27581 Fuse 3.0 Amp Pack of 10

8 Product Catalog 2015

Section 3 Screening Tests

CAT. NO. PRODUCT/ DESCRIPTION CONTENTS 00605* STA®-Neoplastine® CI 5 6 x 5 mL vials of STA® Neoplastine® CI 5 Determination of Prothrombin Time (PT) by STA® analyzers (ISI~1.8). 6 x 5 mL vials of Solvent Freeze-dried rabbit brain thromboplastin with heparin inhibitor.

00606* STA®-Neoplastine® CI Plus 5 6 x 5 mL vials of STA® Neoplastine® CI Plus 5 Determination of Prothrombin Time (PT) by STA® analyzers (ISI~1.3). 6 x 5 mL vials of Solvent Freeze-dried rabbit brain thromboplastin with heparin inhibitor.

00667US* STA®-Neoplastine® CI Plus 10 12 x 10 mL vials of STA® Neoplastine® CI Plus 10 Determination of Prothrombin Time (PT) by STA® analyzers (ISI~1.3). 12 x 10 mL vials of Solvent Freeze-dried rabbit brain thromboplastin with heparin inhibitor.

00595US STA®-PTT Automate 5 12 x 5 mL vials Determination of Activated Partial Thromboplastin Time (APTT) by STA® analyzers. Cephalin reagent with particulate (silica) activator.

00597 STA®-C.K. Prest® 5 6 x 5 mL vials of STA® C.K. Prest® 5 Determination of Activated Partial Thromboplastin Time (APTT) by 6 x 5 mL vials of Activator STA® analyzers. Cephalin reagent with kaolin activator.

00674US STA®-Fibrinogen 5 12 x 5 mL vials Quantitative determination of Fibrinogen by STA® analyzers (Clauss Method). Freeze-dried human thrombin (~80 NIH units/mL) with heparin inhibitor and calcium.

00611 STA®-Thrombin 2 12 x 2 mL vials Determination of Thrombin Time by STA® analyzers. Freeze-dried human thrombin (1.5 NIH units/mL) with calcium.

00669 STA®-Thrombin 10 12 x 10 mL vials Determination of Thrombin Time by STA® analyzers. Freeze-dried human thrombin (1.5 NIH units/mL) with calcium.

00614 STA®-Reptilase® 6 x 2 mL vials Determination of Reptilase® Time. Extracted venom of Bothrops atrox, ~20 BU (Batroxobin unit) per vial.

* ISI values for PT reagents are approximations. Actual ISI values are assigned for each lot of PT reagent.

10 Product Catalog 2015 Factor Assays Section 4

CAT. NO. PRODUCT/ DESCRIPTION CONTENTS 00722 STA®-Deﬁ cient XII 6 x 1 mL vials Substrate plasma for Factor XII assay by STA® analyzers. Freeze-dried human plasma lacking Factor XII.

00723 STA®-Deﬁ cient XI 6 x 1 mL vials Substrate plasma for Factor XI assay by STA® analyzers. Freeze-dried human plasma lacking Factor XI.

00724 STA®-Deﬁ cient IX 6 x 1 mL vials Substrate plasma for Factor IX assay by STA® analyzers. Freeze-dried human plasma from which Factor IX has been removed by selective immuno-adsorption.

00725 STA®-Deﬁ cient VIII 6 x 1 mL vials Substrate plasma for Factor VIII assay by STA® analyzers. Freeze-dried human plasma from which Factor VIII has been removed by selective immuno-adsorption.

00738 STA®-Deﬁ cient X 6 x 1 mL vials Substrate plasma for Factor X assay by STA® analyzers. Freeze-dried human plasma from which Factor X has been removed by selective immuno-adsorption.

00743 STA®-Deﬁ cient VII 6 x 1 mL vials Substrate plasma for Factor VII assay by STA® analyzers. Freeze-dried human plasma from which Factor VII has been removed by selective immuno-adsorption.

00744 STA®-Deﬁ cient V 6 x 1 mL vials Substrate plasma for Factor V assay by STA® analyzers. ['\>%&[+

00745 STA®-Deﬁ cient II 6 x 1 mL vials Substrate plasma for Factor II assay by STA® analyzers. Freeze-dried human serum and absorbed bovine plasma, $#["#%+

00943 Asserachrom® IX:Ag 3 x 2 Coated Strips Enzyme immunoassay of Factor IX Antigen by ELISA method, 96 tests. 3 x 8 mL vials of Anti-IX:Ag-Peroxidase 3 x 8 mL vials of TMB 3 x 50 mL bottles of Dilution Buffer 1 x 50 mL bottle of Washing Solution 3 x 0.5 mL vials of F. IX:Ag Calibrator 3 x 0.5 mL vials of F. IX:Ag Control 1 Plate Frame; 1 Plate Cover

11 Section 5 Anticoagulants

CAT. NO. PRODUCT/ DESCRIPTION CONTENTS Heparin Anti -Xa Chromogenic Assays 00311US STA®-Liquid Anti-Xa 4 6 x 4 mL vials of Reagent 1 (Substrate) Chromogenic assay for the quantitative determination of unfractionated 6 x 4 mL vials of Reagent 2 (F.Xa) (UFH) and low molecular weight heparins (LMWH) in plasma by measuring anti-Xa activity on antithrombin in a competitive assay by STA® analyzers.

00322US STA®-Liquid Anti-Xa 8 6 x 8 mL vials of Reagent 1 (Substrate) Chromogenic assay for the quantitative determination of unfractionated 6 x 8 mL vials of Reagent 2 (F.Xa) (UFH) and low molecular weight heparins (LMWH) in plasma by measuring anti-Xa activity on antithrombin in a competitive assay by STA® analyzers. 00906 Stachrom® Heparin 4 x 2 mL vials of AT III Colorimetric assay of unfractionated and low molecular weight heparins. 2 x 15 mL vials of Buffer %'#"]^+^_>"$`{{{> 4 x 4 mL vials of F. Xa "$[|>"&&+ 4 x 4 mL vials of Substrate

Heparin Induced Thrombocytopenia (HIT) 00615 Asserachrom® HPIA (ELISA) 3 x 2 Coated Strips Determination of anti-heparin - PF4 antibodies by ELISA method, 6 x 2 mL vials of Anti-lgG,A,M-Peroxidase 48 tests. 6 x 8 mL vials of TMB 3 x 30 mL bottles of Dilution Buffer 1 x 50 mL bottle of Washing Solution 3 x 1 mL vials of HPIA Reference 3 x 1 mL vials of Control 1 3 x 1 mL vials of Control 2 1 Plate Frame; 1 Plate Cover

Section 6 Thrombophilia

CAT. NO. PRODUCT/ DESCRIPTION CONTENTS lnhibitors 00516 STA®-Liatest® Free Protein S 6 x 5 mL vials of Buffer lmmuno-turbidimetric assay for Free protein S Antigen by STA® 6 x 6 mL vials of Latex analyzers. Suspension of microparticles coated with monoclonal antibodies to Free Protein S.

00568 Liatest® AT III 6 x 1 mL vials of Latex lmmuno-turbidimetric assay for Antithrombin Antigen. Suspension of 6 x 4 mL vials of Buffer microlatex particles coated with rabbit anti-human AT antibodies.

00570 Liatest® Protein S 6 x 1 mL vials of Latex lmmuno-turbidimetric assay for Total Protein S Antigen. Suspension of 6 x 4 mL vials of Butter Microlatex partlcles coated with rabbit anti-human total protein S antibodies.

12 Product Catalog 2015 Thrombophilia (continued) Section 6

CAT. NO. PRODUCT/ DESCRIPTION CONTENTS 00596 STA®-Stachrom® AT III 4 x 3 mL vials of Thrombin Colorimetric assay of Antithrombin activity by STA® analyzers. Bovine 4 x 3 mL vials of Substrate thrombin ~ 11.3 nKat/mL, freeze-dried. 4 x 3 mL vials of Thrombin Solvent

00671 STA®-Stachrom® Protein C 6 x 3 mL vials of PC-Actlvator Colorimetric assay for the quantitative determination of functional 6 x 3 mL vials of Substrate Protein C by STA®%'+}#%@&`#+ @$&$&=?# "]+&)$+

00746 STA®-Staclot® Protein S @$&== Clotting assay for the quantitative measurement of the functional 2 x 1 mL vials of PCa Protein S level based on the principal of Factor Va inhibition by STA® 2 x 1 mL vials of F.Va analyzers. Lyophilized human plasma, human activated Protein C; bovine Va; free of Protein S.

00747 STA®-Staclot® Protein C ^@$&== Clotting assay of Protein C activity of STA® analyzers. 3 x 1 mL vials of PC-Activator %'&&=#%@& `#+@$&$&=+ Freeze-dried with an activator selected specially for Protein C assay.

00944 Asserachrom® Protein C 3 x 2 Coated Strips Enzyme lmmunoassay for Protein C Antigen 3 x 8 mL vials of Anti-Protein C-Peroxidase by ELISA method, 96 tests. 3 x 8 mL vials of TMB 3 x 50 mL bottles of Dilution Buffer 1 x 50 mL bottles of Washing Solution 3 x 0.5 mL bottles of Protein C Calibrator 3 x 0.5 mL bottles of Protein C Control 1 Plate Frame; 1 Plate Cover

00945 Asserachrom® Total Protein S 3 x 2 Coated Strips One-step enzyme immunoassay for Total Protein S Antigen 3 x 2 mL vials of Anti-Total PS-Peroxidase by ELISA Method, 96 tests. 3 x 8 mL vials of TMB 3 x 50 mL bottles of Dilution Buffer 1 x 50 mL bottles of Washing Solution 3 x 0.5 mL bottles of Total Protein S Calibrator 3 x 0.5 mL bottles of Total Protein S Control 1 Plate Frame; 1 Plate Cover

00946 Asserachrom® Free Protein S 3 x 2 Coated Strips One-step enzyme immunoassay for Free Protein S Antigen 3 x 2 mL vials of Anti-Free PS-Peroxidase by ELISA Method, 96 tests. 3 x 8 mL vials of TMB 3 x 50 mL bottles of Dilution Buffer 1 x 50 mL bottles of Washing Solution 3 x 0.5 mL bottles of Free Protein S Calibrator 3 x 0.5 mL bottles of Free Protein S Control 1 Plate Frame; 1 Plate Cover

13 Section 6 Thrombophilia (continued)

CAT. NO. PRODUCT/ DESCRIPTION CONTENTS Lupus Anticoagulants 00339 STA®-Staclot® DRVV Screen 2 12 x 2 mL vials Detection of Lupus Anticoagulants by the diluted Russell’s viper venom test by STA® analyzers. Russell’s viper venom, phospholipids (low concentration), calcium and heparin inhibitor, freeze-dried.

00333 STA®-Staclot® DRVV Screen 5 12 x 5 mL vials Detection of Lupus Anticoagulants by the diluted Russell’s viper venom test by STA® analyzers. Russell’s viper venom, phospholipids (low concentration), calcium and heparin inhibitor, freeze-dried.

00334 STA®-Staclot® DRVV Conﬁ rm 12 x 2 mL vials Detection of Lupus Anticoagulants by the diluted Russell’s viper venom test by STA® analyzers. Russell’s viper venom, phospholipids (high concentration), calcium and heparin inhibitor, freeze-dried.

00600 Staclot® LA 2 x 1 mL vials of Buffer Detection of Lupus Anticoagulants. 2 x 0.25 mL vials of Phospholipids Freeze-dried hexagonal phase phosphatidylethanolamine, normal 4 x 0.5 mL vials of Normal Plasma human plasma with heparin inhibitor, PTT-LS reagent of cephalin and 2 x 1 mL vials of PTT-LS particulate activator (silica), 10 tests. 2 x 1.5 mL vials of Solvent

00594 Staclot® LA 20 2 x 1 mL vials of Buffer Detection of Lupus Anticoagulants. 2 x 0.5 mL vials of Phospholipids Freeze-dried hexagonal phase phosphatidylethanolamine, normal 4 x 0.5 mL vials of Normal Plasma human plasma with heparin inhibitor, PTT-LS reagent of cephalin and 2 x 2 mL vials of PTT-LS particulate activator (silica), 20 tests. 2 x 2.5 mL vials of Solvent

00599 PTT-LA (LA Screen) 6 x 2 mL vials Lupus Anticoagulant sensitive APTT reagent. Cephalin reagent with particulate activator (silica), freeze-dried.

14 Product Catalog 2015 Fibrin Formation & Degradation Section 7

CAT. NO. PRODUCT/ DESCRIPTION CONTENTS 00515 STA®-Liatest® D-Di 6 x 5 mL vials of Buffer Immuno-turbidimetric assay of D-dimer by STA® analyzers. Microlatex 6 x 6 mL vials of Latex particles coated with two different mouse monoclonal anti-human D-dimer antibodies.

00947 Asserachrom® D-Di 3 x 2 Coated Strips Enzyme immunoassay of D-dimer by ELISA method, 96 tests. 3 x 8 mL vials of Anti-D-Peroxidase 3 x 8 mL vials of TMB 3 x 50 mL bottles of Dilution Buffer 1 x 50 mL bottle of Washing Solution 3 x 0.5 mL vials of D-Di Calibrator 3 x 0.5 mL vials of D-Di Control 1 Plate Frame; 1 Plate Cover

00454 D-Di Test® 1 x 1.3 mL vial of Latex Latex aggultination slide test for the qualitative and semi-quantitative 1 x 20 mL bottle of Buffer determination of D-dimer in plasma, 60 tests. 1 x 1 mL vial of Negative Control 1 x 1 mL vial of Positive Control 10 - Test Cards; Mixing Rods

00550 Test cards for D-Di Test kit 10 test cards 00540 FDP Plasma 1 x 1.3 mL vial of latex $\$&"## 1 x 1.3 mLvial of negative control products (FDP) in plasma by latex agglutination. 1 x 1.3 mL vial of positive control 1 x 1.3 mL vial of buffer 10 test cards mixing rods

00541 FDP Plasma (Latex) 12 x 1.3 mL vials of x 20 latex 00551 FDP Plasma (Buffer) 12 vials of buffer 00548 F.S./FDP Plasma Test Cards 10 test cards For use with catalog #00540 and #00887.

00887 F.S. Test Unit 8 x 0.2 mL vials of F.S. Test Unit Reagent &""@"%##> 8 x 0.2 mL vials of Positive Control 32 tests. 8 x 0.2 mL vials of Negative Control 10 - Test Cards

00857 F.S. Test 4 x 0.5 mL vials of F.S. Test Reagent ]&""@"%##> 4 x 0.5 mL vials of Positive Control 40 tests. 4 x 0.5 mL vials of Negative Control

15 Section 8 Fibrinolysis

CAT. NO. PRODUCT/ DESCRIPTION CONTENTS 00658 STA®-Stachrom® Plasminogen 6 x 3 mL vials of Streptokinase Colorimetric assay of plasminogen activity by STA® analyzers. 6 x 3 mL vials of Substrate

00659 STA®-Stachrom® Antiplasmin 4 x 2 mL vials of Plasmin Colorimetric assay of antiplasmin activity by STA® analyzers. 4 x 6 mL vials of Substrate 4 x 2 mL vials of Plasmin Solvent

00948 Asserachrom® tPA 3 x 2 Coated Strips Enzyme immunoassay of tissue plasminogen activator 3 x 8 mL vials of Anti-tPA-Peroxidase antigen by ELISA method, 96 tests. 3 x 8 mL vials of TMB 3 x 50 mL bottle of Dilution Buffer 1 x 50 mL bottle of Washing Solution 3 x 0.5 mL vials of tPA Calibrator 3 x 0.5 mL vials of tPA Control 1 Plate Frame: 3 Adhesive Films

Section 9 Primary Hemostasis

CAT. NO. PRODUCT/ DESCRIPTION CONTENTS 00518 STA®-Liatest® VWF:Ag 4 x 5 mL vials of Buffer lmmuno-turbidimetric assay of Von Willebrand Factor 4 x 2 mL vials of Latex (VWF:Ag) Antigen by STA ® analyzers. 4 x 4 mL vials of Latex Diluent Microlatex particles coated with rabbit anti-human VWF antibodies.

00942 Asserachrom® VWF:Ag 3 x 2 Coated Strips Enzyme immunoassay of Von Willebrand Factor Antigen 3 x 8 mL vials of Anti-VWF-Peroxidase by ELISA method, 96 tests. 3 x 8 mL vials of TMB 3 x 50 mL bottles of Dilution Buffer 1 x 50 mL bottle of Washing Solution 3 x 0.5 mL vials of VWF:Ag Calibrator 3 x 0.5 mL vials of VWF:Ag Control 1 Plate Frame; 1 Plate Cover

00950 Asserachrom® -TG 3 x 2 Coated Strips Enzyme immunoassay for -Thromboglobulin Antigen 3 x 8 mL vials of Anti- -TG-Peroxidase by ELISA method, 96 tests. 3 x 8 mL vials of TMB 3 x 50 mL bottles of Dilution Buffer 1 x 50 mL bottle of Washing Solution 3 x 0.5 mL vials of -TG Calibrator 3 x 0.5 mL vials of -TG Control 1 Plate Frame; 1 Plate Cover

00951 Asserachrom® PF4 3 x 2 Coated Strips Enzyme immunoassay for Platelet Factor 4 3 x 8-mL vials of Anti-PF4-Peroxidase by ELISA method, 96 tests. 3 x 8 mL vials of TMB 3 x 50 mL bottles of Dilution Buffer 1 x 50 mL bottle of Washing Solution 3 x 0.5 mL vials of PF4 Calibrator 3 x 0.5 mL vials of PF4 Control 1 Plate Frame; 1 Plate Cover

16 Product Catalog 2015 Control Plasmas Section 10

CAT. NO. PRODUCT/ DESCRIPTION CONTENTS 00381 STA®-Quality HNF/UFH 6 x 1 mL vials of STA® Quality HNF/UFH 2 Control plasma for assay of unfractionated heparin (UFH) 6 x 1 mL vials of STA® Quality HNF/UFH 5 using the STA ® Liquid Anti-Xa method on STA® analyzers.

00676 STA®-Coag Control N + ABN 12 x 1 mL vials of STA® Coag Control N Multi-constituent normal and abnormal plasma controls for routine assays 12 x 1 mL vials of STA® Coag Control ABN performed on the STA® analyzers.

00678 STA®-System Control N + P 12 x 1 mL vials of STA® System Control N Multi-constituent normal and abnormal plasma controls for routine and 12 x 1 mL vials of STA® System Control P specialty assays performed on the STA® analyzers.

00526US STA®-Liatest® Control N + P 12 x 1 mL vials of STA® Liatest® Control N Normal and abnormal control plasmas for immuno-turbidimetric assays 12 x 1 mL vials of STA® Liatest® Control P of VWF, D-dimer and Free Protein S on STA® analyzers. For use with STA® Liatest® VWF:Ag (#00518), STA® Liatest® D-DI (#00515) and STA® Liatest® Free Protein S (#00516). 00682 STA®-HBPM/LMWH Control 6 x 1 mL vials of STA®- Quality HBPM/LMWH Control 3 Control plasma for LMWH assay using anti-Xa method 6 x 1 mL vials of STA®- Quality HBPM/LMWH Control 8 (Stachrom® Heperarin).

00683 STA®-Heparin Control 6 x 1 mL vials of STA® Heparin Control 2 Control plasma for assays of unfractionated heparins (UFH) using 6 x 1 mL vials of STA® Heparin Control 5 the Anti-Xa method on STA® analyzers.

00686 STA®-Quality HBPM/LMWH 6 x 1mL vials of STA® Quality HBPM/LMWH Control 8 Control plasma for assays of low molecular weight heparins (LMWH) 6 x 1mL vials of STA® Quality HBPM/LMWH Control14 using the Anti-Xa method on STA® analyzers.

00201 STA®-Control LA 1 + 2 3 x 1 mL vials of STA® Control LA 1 Control plasmas for lupus anticoagulant (LA) detection. 3 x 1 mL vials of STA® Control LA 2

17 Section 11 Calibrators

CAT. NO. PRODUCT/ DESCRIPTION CONTENTS 00348 STA®-Multi Hep Calibrator 4 X 1 mL vials of STA® Multi Hep Calibrator 0 Calibration plasmas for both UFH and LMWH using 4 X 1 mL vials of STA® Multi Hep Calibrator 4 the STA® Liquid Anti-Xa method on the STA® analyzers. 4 X 1 mL vials of STA® Multi Hep Calibrator 7 4 X 1 mL vials of STA® Multi Hep Calibrator 10 4 X 1 mL vials of STA® Multi Hep Calibrator 18

00681 STA®-Hepanorm® HBPM/LMWH 4 x 1 mLvials of STA® - Hepanorm® HBPM/LMWH 0 Calibration plasma for LMWH assay using anti-Xa method. 4 x 1 mL vials of STA® - Hepanorm® HBPM/LMWH 4 (Stachrom® Heparin) 4 x 1 mL vials of STA® - Hepanorm® HBPM/LMWH 9

00684 STA®-Hepanorm® H 4 x 1 mL vials of STA® Hepanorm® H 0 Calibration plasmas for assays of unfractionated heparin (UFH) 4 x 1 mL vials of STA® Hepanorm® H 3 using the Anti-Xa method on STA® analyzers. 4 x 1 mL vials of STA® Hepanorm® H 6

00520 STA®-VWF:Ag Calibrator 6 x 1 mL vials Citrated human plasma for the calibration of VWF assays by the immuno-turbidimetric method on STA® analyzers. For use with STA® Liatest® VWF:Ag (#00518).

00675 STA®-Unicalibrator 6 x 1 mL vials Multi-constituent calibration plasma for functional assays of coagulation parameters on STA® analyzers.

Section 12 Auxiliary Reagents

CAT. NO. PRODUCT/ DESCRIPTION CONTENTS

00279 Polyethylene Glycol (PEG 25%) 6 x 2.5 mL

00360 STA®-Owren-Koller Buffer 24 x 15 mL

00367 ® 24 x 15 mL STA -CaCl2 0.025M

00555 Asserachrom® Washing Solution 2 x 50 mL

00973 STA®-Cleaner Solution 6 x 2.5 L

00975US STA®-Desorb U 24 x 15 mL

18 Product Catalog 2015 Quality & Compliance Solutions Section 13

CAT. NO. PRODUCT/ DESCRIPTION CONTENTS EQA (External Quality Assessment) Qualiris by Stago i%##+#=>`=>["#>" hemostasis tests and a wide variety of specialty tests including D-dimer, unfractionated heparin, low molecular weight heparin, factor assays and thrombophilia assays. Qualiris also offers a diagnostic challenge module for use as competency testing to satisfy continuing education requirements. Qualiris is an easy to use, web-based system which provides monthly, biannual, and annual reports with quantitative and qualitative statistics. Contact your sales representative for more information and to set up a custom comparison group. IQC (Internal Quality Control) Clarity Check Peer Program by Stago is a comprehensive quality control management program that offers peer comparison with the ability to create custom peer groups, pre-loaded reagent and QC lot information, 24/7 secure web based program with no need for additional hardware or software, and @"%$?%$%%+ Core Programs 85145 Clarity Check Peer Program Clarity Check is a comprehensive quality control management program that offers: • peer comparison with the ability use create custom peer groups • pre-loaded reagent and QC lot information • 24/7 secure web based program with no need for additional hardware or software #@"%$?%$ 01044 Qualiris QC Premium Semester 1 12 x 1 mL Monthly external quality assessment of PT, APTT, Fibrinogen, Thrombin Time. 01045 Qualiris QC Premium Semester 2 12 x 1 mL Monthly external quality assessment of PT, APTT, Fibrinogen, Thrombin Time. 01046 Qualiris QC Experience 6 x 1 mL Twice per year external quality assessment of PT, APTT, Fibrinogen, Thrombin Time. Optional Add-On Programs 85093 Qualiris QC Premium Factors Monthly external quality assessment of Factors II, V, VII, VIII, IX, X, XI, XII, & VWF. 85094 Qualiris QC Premium Thrombophilia Monthly external quality assessment of Antithrombin, Protein C, Protein S, Plasminogen, Antiplasmin. 85098 Qualiris QC Experience Factors Biannual external quality assessment of Factors II, V, VII, VIII, IX, X, XI, XII, & VWF. 85099 Qualiris QC Experience Thrombophilia Biannual external quality assessment of Antithrombin, Protein C, Protein S, Plasminogen, Antiplasmin. 01047 Qualiris QC Heparin HBPM / LMWH 6 x 1 mL External quality assessment of low molecular weight heparins. (6 times per year) 01048 Qualiris QC Heparin HNF / UFH 6 x 1 mL External quality assessment of unfractionated heparin. (6 times per year) 01049 Qualiris QC D-dimer 6 x 1 mL External quality assessment of D-dimer. (6 times per year) 01063 Qualiris QC Lupus Anticoagulant 3 x 1 mL External quality assessment of lupus anticoagulant. (3 times per year) 01050 Qualiris Diagnostic Challenge 6 x 1 mL Competency assessment with unassayed sample and a Clinical Case History for CE credit.(3 cases per year)

19 Section 14 Stago Added Value on Request (SAVOR™)

SAVOR™ (Stago Added Value on Request) offers tailored solutions for training, inventory management and other services $%&%+[##%#`#+

Basic Operator Training Training at our Parsippany, New Jersey facility is included with each new instrument purchased. Price includes transportation, hotel, meals and training manuals for in-house training.

CAT. NO. INSTRUMENT COURSE DESCRIPTION DAYS 08416 STA Compact® In-House Basic Operator Training - STA Compact® 2.5

Following the completion of this course, participants will be able to: • Recognize analyzer hardware • Prepare and load consumables/reagents • Complete practice runs included in the training manual • Understand the software • Perform user maintenance functions on the analyzer • Perform method validation/lot conversion

CAT. NO. INSTRUMENT COURSE DESCRIPTION DAYS 08417 STA-R Evolution® In-House Basic Operator Training - STA-R Evolution® 4.0

Following the completion of this course, participants will be able to: • Recognize analyzeer hardware • Prepare and load consumables/reagents • Load patient samples on the analyzer and order tests • Complete practice runs included in the training manual • Understand the software • Perform user maintenance functions on the analyzer • Perform method validation/lot conversion

20 Product Catalog 2015 Stago Added Value on Request (SAVOR™) cont. Section 14

On-Site Basic Operator Training One-Site Key Operator Training: For these customers who are unable to attend training at our Parsippany, New Jersey training facility, a member of the Stago Training Team will be assigned to visit the laboratory and conduct the Basic Operator Training.

CAT. NO. INSTRUMENT COURSE DESCRIPTION DAYS 08419 STA Compact® On-Site Basic Operator Training - STA Compact® 2

Following the completion of this course, participants will be able to: • Recognize analyzer hardware • Prepare and load consumables/reagents • Load patient samples on the analyzer and order tests • Complete practice runs included in the training manual • Understand the software • Perform user maintenance functions on the analyzer • Perform method validation/lot conversion

CAT. NO. INSTRUMENT COURSE DESCRIPTION DAYS 08420 STA-R Evolution® On-Site Basic Operator Training - STA-R Evolution® 3

Following the completion of this course, participants will be able to: • Recognize analyzeer hardware • Prepare and load consumables/reagents • Load patient samples on the analyzer and order tests • Practice loading patient samples on the analyzer and order tests • Complete practice runs included in the training manual • Understand the software • Perform user maintenance functions on the analyzer • Perform method validation/lot conversion

CAT. NO. INSTRUMENT COURSE DESCRIPTION DAYS 08418 Calibrated On-Site Basic Operator Training - CAT 1 Automated Thrombogram

Following the completion of this course, participants will be able to: • Recognize analyzer hardware • Prepare and load consumables / reagents • Use and apply Thrombinoscope software • Analyze samples on the instrument and perform data analysis

On-Site Training includes installation of the CAT analyzer.

21 Section 14 Stago Added Value on Request (SAVOR™) cont.

Experienced Operator Training (Current User/ Software Upgrade): The Experienced Operator Training course is designed for institutions that have been using a Stago instrument and are replacing their existing instrument with the same or similar model. Experienced Operator Training is typically conducted by members of the Field Support Group at the customer’s facility.

CAT. NO. INSTRUMENT COURSE DESCRIPTION DAYS 08421 STA Compact® Experienced Operator Training - STA Compact® 1 day 4 hours/class 3 techs/class

This condensed class builds on skills learned in the Basic Course. Following the completion of this course, participants will: • Recognize hardware areas on the analyzer • Understand the software • Perform user maintenance functions on the analyzer • Demonstrate advanced troubleshooting skills • Demonstrate advanced technical knowledge

CAT. NO. INSTRUMENT COURSE DESCRIPTION DAYS 08422 STA-R Evolution® Experienced Operator Training - STA-R Evolution® 1.5 day 4 hours/class 3 techs/class

Advanced Operator Training Advanced Operator Training is designed as an advanced troubleshooting program. The course is conducted by a member of the Stago Training Team at the customer’s facility.

CAT. NO. INSTRUMENT COURSE DESCRIPTION DAYS 08423 STA Compact® Advanced Operator Training - STA Compact® 2 days 4 hours/class up to 2 classes/day 2 techs/class This class builds on skills learned in the Basic Course. It is designed based on customer needs. Following the completion of this course, participants will: • Demonstrate advanced troubleshooting skills • Demonstrate advanced technical knowledge

CAT. NO. INSTRUMENT COURSE DESCRIPTION DAYS 08424 STA-R Evolution® Advanced Operator Training - STA-R Evolution® 2 days 6 hours/class 3 techs/class

This class builds on skills learned in the Basic Course. It is designed based on customer needs. Following the completion of this course, participants will: • Demonstrate advanced troubleshooting skills • Demonstrate advanced technical skills

22 Product Catalog 2015 Stago Added Value on Request (SAVOR™) cont. Section 14

Reagent Application Technical Support 08427 On-Site Technical Assistance

The Stago Technical Support Specialist will assist with adding a test parameter to a Stago instrument. Assistance could include test set-up, method validation, running test samples, and data collection and analysis.

Stago Inventory Management 08431 Inventory Management and Shipping

Stago often receives requests for customized inventory management solutions, including sequestering of products that typically would not be sequestered. A nominal fee is to charged for this customized solution. Requirements include: #}%?% • Shipping schedule including beginning and end dates

Lab Automation The STA-R Evolution® can be integrated into a lab automation line. To accomplish the connection, a connection kit and/or additional accessory items may be required. A Stago automation consultant is available to answer questions and assure a smooth transition.

CAT. NO. ACCESSORIES 80200 Beckman Line Line Kit and Platform

80138 Beckman Line Ramp and Adjustment System

80140 Beckman Line Platform Foot Assembly (may not be necessary)

80210 Siemens Ramp and Adjustment System

88517 Labotix Connection Kit

88541 Labotix Ramp and Adjustment System

23 Section 14 Stago Added Value on Request (SAVOR™) cont.

Advanced Training Workshop Instrument Workshop: 1 full day Customized to meet the needs of your laboratory, the agenda is a combination of lectures and hands-on instrument exercises. Continuing education credits available.

CAT. NO. COURSE DESCRIPTION 08432 Advanced Training Workshop

Method Validation

Standard Service: Accurate method validation is key to maintaining standardization and quality of results. In depth training and tools are provided during the new instrument training program. Standard method validation services include telephone support by your Stago Technical &$?&>?>$$?+ SAVOR Method Validation Service: For customers who would prefer to have a Stago Technical Support Specialist on-site to coordinate and perform method validation, the Technical Support Specialist will run the tests, collect data, perform data analysis and provide an electronic data presentation.

CAT. NO. DAYS OF ON-SITE SUPPORT SERVICE DESCRIPTION 08428 3 Routine Assays: PT, APTT, Fib, TT, D-dimer

08429 4 Routine + Specialty Assays

CAT. NO. DESCRIPTION 85080 Method Validation Binder: For customers without access to a network enabled computer, Stago provides the convenience of a paper report.

Lot Conversion

Lot Conversion/Simple Method Validation (eg. a single test parameter) Lot Conversion: For customers who would prefer to have a Stago Technical Support Specialist on-site to perform a lot conversion, the Technical Support Specialist will run the tests, collect data, perform data analysis and provide an electronic data presentation. Method Validation: A Stago Technical Support Specialist will be on-site for one full day to perform method validation studies. Prior to arrival, the Technical Support Specialist will work with the lead coagulation technologist/key operator to develop the plan for sample requirements and time management. The Technical Support Specialist will schedule a time to be present to run samples, generate data and complete the process.

CAT. NO. DAYS OF ON-SITE SUPPORT SERVICE DESCRIPTION 08430 1 Routine Assay Lot Conversion

24 Product Catalog 2015 Stago Added Value on Request (SAVOR™) cont. Section 14

Preventive Maintenance on Demand Preventive Maintenance on Demand is designed for customers who have a backup instrument that does not include a service contract. The Stago Field Service Group will perform a preventative maintenance program which includes decontamination of the instrument, general #>">&>"#&+=$>"+

CAT. NO. INSTRUMENT SERVICE DESCRIPTION 85075 STA Compact® Preventative Maintenance

85076 STA-R Evolution® Preventative Maintenance

Instrument Decommission A Stago Field Service Engineer will decontaminate your retired coagulation instrument and remove the hard drive in compliance with local regulatory and HIPAA requirements.

CAT. NO. SERVICE DESCRIPTION 85077 Decommission

85078 Decommission and return instrument to Stago for disposal

85079 Special visit to perform decommission procedure

Lot Conversion Analysis

A Stago Technical Support Specialist will receive data generated by the lab via email, fax or other locally acceptable means of sharing data. The Technical Support Specialist will load the data into the appropriate template, review data for outliers, and provide a report back to the customer.

CAT. NO. SERVICE DESCRIPTION 08434 TSS Assistance: Lot Conversion Analysis

25 Section 15 Thrombin Generation Research Products (Research Use only, not for diagnostic procedures)

CAT. NO. PRODUCT/ DESCRIPTION CONTENTS Instrument 86186 Calibrated Automated Thrombogram® Thermo Electron Fluoroskan Ascent Analyzer The Calibrated Automated Thrombogram® (CAT) measures Computer the concentration of thrombin generated over time in clotting plasma Thrombinoscope Software using either platelet poor or platelet rich plasma. Operator’s reference manual `&">&& Dongle color differences between plasmas by running a calibrator with every patient Filters: 1 - 390 nm, 1- 460 nm sample. The CAT provides a description of hyper- as well as hypo-activity of the clotting system.

Reagents 86192 Thrombin Calibrator 20 x 16 tests &">&& differences between plasmas, which is necessary for use in parallel with each sample.

86193 PPP Reagent 20 x 16 tests Used with platelet poor plasma for general applications using the CAT System.

86194 PPP Reagent Low 20 x 16 tests Used with platelet poor plasma and has a high sensitivity to Factors VIII, IX and XI. This reagent increases sensitivity in hemophiliac plasma.

86195 PPP Reagent High 20 x 16 tests Used with platelet poor plasma when thrombin generation is strongly inhibited. This reagent increases sensitivity in plasmas containing anticoagulants such as heparin. 86196 PRP Reagent 20 x 16 tests Used with platelet-rich plasma for thrombin generation measurements. PRP-Reagent can also be used in platelet-poor plasma to determine the presence of phospholipids and to examine the activity of phospholipid microparticles.

86197 FluCa Kit 10 x 16 tests #""&&"&"#+

86222 MP Reagent 20 x 16 tests ?\&%$# Tissue Factor present on the surface of procoagulant microparticles.

Disposables & Accessories 86175 Immulon Round Bottom plate, 2HB 50/box

86176 Dispensing Tip 1 tip 1 replacement tip for use with dispenser tip assembly of Calibrated Automated Thrombogram (CAT) instrument. 86191 Thrombinoscope Package 1 Thrombinoscope software and 1 dongle Trombinoscope Software and dongle for running thrombin generation experiments via the Calibrated Thrombogram (CAT) platform. The Thrombinoscope Package can be purchased separately if the user already has a Fluoroskan Ascent® FL or Ascent® instrument along with a desktop computer with a RS232 serail port connection available.

26 Product Catalog 2015 COMING SOON: Ecarin Chromogenic Assay (ECA) Products Section 16 (Research Use only, not for diagnostic procedures)

CAT. NO. PRODUCT/ DESCRIPTION CONTENTS 01108 STA®-ECA II 2 x 3.5 mL Prothrombin Reagent Quantitative determination of dabigatran in plasma samples by the Ecarin 2 x 2 mL Substrate Chromogenic Assay (ECA) method. 2 x 2 mL Ecarin Reagent

01109 STA®-Dabigatran Calibrator 2 x 1 mL vials of Calibrator 0 Calibration plasmas for dabigatran measurement using Ecarin 2 x 1 mL vials of Calibrator 1 Chromogenic Assay method. 2 x 1 mL vials of Calibrator 2 2 x 1 mL vials of Calibrator 3 2 x 1 mL vials of Calibrator 4

01110 STA®-Dabigatran Control 3 x 1 mL Vials of Control 1 Control plasmas for dabigatran measurement using Ecarin Chromogenic 3 x 1 mL Vials of Control 2 Assay method.

Flow Cytometry Research Products Section 17 (Research Use only, not for diagnostic procedures)

CAT. NO. PRODUCT/ DESCRIPTION CONTENTS Flow Cytometry research kits from BioCytex 00111 Platelet Gp Receptors 5 tests

The PLT Gp/Receptors kit allows precise quantitation of GpIIb, GpIb and GMP140 glycoproteins on platelet surfaces in the resting state and after TRAP (Thrombin Receptor Agonist Peptide) activation for detection of constitutive thrombopathies, including Glanzmann Thrombasthenia, Bernard Soulier syndrome, Fechtner syndrome, X-linked thrombocytopenia, and Gray platelet syndrome.

00112 Platelet Gpllb/llla Occupancy 10 tests

#?%%&{{"{{{#%&#&%"%$\{{"{{{ drugs including abciximab (Reopro®>"{#®>"`##®).

00418 Platelet Gp Screen 10 tests

#?%%&#%{{{>{"{+

00420 Megamix 50 tests

['#?#$%#!+\)$##"%+

00449 Platelet VASP/P2Y12 10 tests

[$#&`==#>##=$@®>#&®), and ticagrelor (Brilinta®).

00452 Platelet PAlg Kit 10 tests

[?%%&=`{#"=`{#+

00457 Platelet Calibrator 5 curves

Calibration kit for the measurement of platelet glycoprotein expression level or any other human platelet surface molecules.

01000 Cellquant PNH 12 tests

[%&&_#%&&&%'#& suspected of Paroxysmal Nocturnal Haemoglobinuria (PNH).

01001 Cellquant Calibrator 5 curves

Calibration kit for the measurement of human leukocyte surface antigen expression level by multiple color analysis.

01003 Redquant PNH 12 tests

[%&&_"&&&%'#& suspected of Paroxysmal Nocturnal Haemoglobinuria (PNH).

01077 Megamix-Plus FSC 50 tests

For standardizing microparticle setup within a given analysis region (0.3-1 μm) and providing setting stability. Designed for use with ?#&?[\'?%® or Navios® from Beckman Coulter.

01078 Megamix-Plus SSC 50 tests

For standardizing microparticle setup within a given analysis region (0.3-1 μm) and providing setting stability. Designed for use ??#&?\'?%&]+

29 Section 17 Flow Cytometry Research Products (continued) (Research Use only, not for diagnostic procedures)

CAT. NO. PRODUCT/ DESCRIPTION CONTENTS Monoclonal antibodies for ﬂ ow cytometry from BioCytex 01005 Fibrinogen, clone 9F9, FITC 100 tests

01006 CD146, clone COM3D9, puriﬁ ed 100 tests

01007 CD146, clone COM2F6, puriﬁ ed 100 tests

01008 CD146, clone COM5G6, puriﬁ ed 100 tests

01009 CD146, clone COM7A4, Biotin 100 tests

01010 CD146, clone COM7A4, FITC 100 tests

01011 CD146, clone COM7A4, puriﬁ ed 100 tests

01012 CD146, clone S-Endo 1, Biotin 100 tests

01013 CD146, clone S-Endo 1, FITC 100 tests

01014 CD146, clone S-Endo 1, puriﬁ ed 100 tests

01015 CD146, clone S-Endo 1, PE 100 tests

01016 CD61, clone 4F8, FITC 100 tests

01017 CD61, clone 4F8, puriﬁ ed 100 μg

01018 Ctl. neg. lgG1 - FITC (2DNP2H11) 100 tests

01019 Ctl. neg. lgG1 puriﬁ ed (2DNP2H11) 100 μg

01020 Ctl. neg. lgG1 - PE (2DNP2H11) 100 tests

01021 CD62P, clone LYP20, FITC 100 tests

01022 CD62P, clone LYP20, puriﬁ ed 100 μg

01023 CD62P, clone LYP20, PE 100 tests

01024 CD41, clone PL2-49, FITC 100 tests

01025 CD41, clone PL2-49, puriﬁ ed 100 μg

01026 CD41, clone PL2-49, PE 100 tests

01027 CD42b, clone ALMA 19, FITC 100 tests

01028 CD42b, clone ALMA 19, puriﬁ ed 100 μg

01029 CD42b, clone ALMA 19, PE 100 tests

01030 CD36, clone 10.5, FITC 100 tests

01031 CD36, clone 10.5, puriﬁ ed 100 μg

30 Product Catalog 2015 Section 17 Flow Cytometry Research Products (continued) (Research Use only, not for diagnostic procedures)

CAT. NO. PRODUCT/ DESCRIPTION CONTENTS Monoclonal antibodies for ﬂ ow cytometry from BioCytex 01032 CD36, clone 10.5, PE 100 tests

01033 CD32, clone 2B2, puriﬁ ed 100 μg

01034 Ctl. neg. lgG2b-FITC (2DNP14G5) 100 tests

01035 Ctl. neg. lgG2b puriﬁ ed (2DNP14G5) 100 μg

01036 Ctl. neg. lgG2b PE (2DNP14G5) 100 tests

01037 Ctl. neg. lgG2a-FITC (2DNP16C12) 100 tests

01038 Ctl. neg. lgG2a puriﬁ ed (2DNP16C12) 100 μg

01039 Ctl. neg. lgG2a - PE (2DNP16C12) 100 tests

01040 CD61, clone LYP18, FITC 100 tests

01041 CD61, clone LYP18, puriﬁ ed 100 μg

01042 CD61, clone LYP18, PE 100 tests 100 μg

01083 Anti-human GPVI, puriﬁ ed 100 μg

01084 Anti-human GPVI, PE 100 tests

31 Section 18 Research Kits (Research Use only, not for diagnostic procedures)

CAT. NO. PRODUCT/ DESCRIPTION CONTENTS 00261 Asserachrom® Total TFPI 3 x 2 Coated Strips Quantitative determination of total Tissue Factor Pathway Inhibitor (TFPI) 3 x 2 mL vials of Anti-Total TFPI-Peroxidase by ELISA method, 96 tests. 6 tablets of Ortho-Phenylenediamine 2 x 50 mL bottles of Dilution Buffer 1 x 50 mL bottle of Washing Solution 3 x 0.5 mL vials of Total TFPI Calibrator 3 x 0.5 mL vials of Total TFPI Control 1 Plate Frame; 1 Plate Cover 6 tablets of Urea Peroxide 00262 Asserachrom® Free TFPI 3 x 2 Coated Strips Quantitative determination of free Tissue Factor Pathway Inhibitor (TFPI) 3 x 2 mL vials of Anti-Free TFPI-Peroxidase by ELISA method, 96 tests. 6 tablets of Ortho-Phenylenediamine 6 tablets of Urea Peroxide 2 x 50 mL bottles Dilution Buffer 1 x 50 mL bottle of Washing Solution 3 x 0.5 mL vials of Free TFPI Calibrator 3 x 0.5 mL vials of Free TFPI Control 1 Plate Frame; 1 Plate Cover 00264 Asserachrom® sEPCR 3 x 2 Coated Strips Quantitative determination of soluble Endothelial Protein C Receptor by 3 x 8 mL vials of Anti-sEPCR-Peroxidase ELISA method, 96 tests. 3 x 8 mL vials of TMB 3 x 50 mL bottles of Dilution Buffer 1 x 50 mL bottle of Washing Solution 3 x 0.5 mL vials of sEPCR Calibrator 3 x 0.5 mL vials of sEPCR Control 1 Plate Frame; 1 Plate Cover

00265 Asserachrom® Anti-Prothrombin IgG,M 3 x 2 Coated Strips Semi-quantitative determination of anti-prothrombin antibodies of IgG 3 x 4 mL vials of Anti-IgG-Peroxidase and/or IgM class by ELISA method, 96 tests. 3 x 4 mL vials of Anti-IgM-Peroxidase 3 x 8 mL vials of TMB 3 x 50 mL bottles of Dilution Buffer 1 x 50 mL bottle of Washing Solution 3 x 2 mL vials of Anti-Prothrombin IgG,M Calibrator 3 x 2 mL vials of Control 1 3 x 2 mL vials of Control 2 1 Plate Frame; 1 Plate Cover

00276 Asserachrom® Soluble GPV 3 x 2 Coated Strips Quantitative determination of soluble Glycoprotein V 3 x 8 mL vials of Anti-sGPV-Peroxidase by ELISA method, 96 tests. 3 x 8 mL vials of TMB 3 x 50mL bottles of Dilution Buffer 1 x 50 mL bottle of Washing Solution 3 x 0.5 mL vials of sGPV Calibrator 3 x 0.5 mL vials of sGPV Control 1 Plate Frame; 1 Plate Cover

00280 Asserachrom® VIII:Ag 3 x 2 Coated Strips Quantitative determination of Factor VIII Antigen 3 x 8 mL vials of Anti- F.VIII:Ag-Peroxidase by ELISA method, 96 tests. 3 x 8 mL vials of TMB 3 x 50mL bottles of Dilution Buffer 1 x 50 mL bottle of Washing Solution 3 x 0.5 mL vials of F. VIII:Ag Calibrator 3 x 0.5 mL vials of F. VIII:Ag Control 1 Plate Frame; 3 Adhesive Films

00281 Staclot® VIIa-rTF 2 x 2 mL vials of Buffer Clotting assay of activated Factor VII, 20 tests. @$&[+{{= 2 x 1 mL vials of rsTF-Phospholipids 2 x 0.5 mL vials of F. VIIa Calibrator 2 x 0.5 mL vials of F. VIIa Control 1 2 x 0.5 mL vials of F. VIIa Control 2

32 Product Catalog 2015 Research Kits (continued) Section 18 (Research Use only, not for diagnostic procedures)

CAT. NO. PRODUCT/ DESCRIPTION CONTENTS 00346 STA®-Stachrom® TAFI 2 x 2 mL vials of TAFI Activator $&"$""% 2 x 2 mL vials of Substrate inhibitor activity, Chromogenic Assay, 60 tests. 4 x 4 mL vials of Carboxypeptidase A 2 x 1 mL vials of TAFI Calibator 2 x 1 mL vials of TAFI Control

00429 STA®-Procoag-PPL 3 x 1 mL vials of P-PPL Depleted plasma Clot-based assay for the detection of procoagulant phospholipids by 3 x 4 mL vials of F.Xa, ~0.040 IU/vial STA® analyzer, 60 tests. 3 x 1 mL vials of P-PPL Control N 3 x 1 mL vials of P-PPL Control P

00491 Asserachrom® Vlla-AT 3 x 2 Coated Strips Quantitative determination of the FVlla-AT complex 3 x 8 mL vials of Anti-AT-Peroxidase by ELISA method, 96 tests. 3 x 8 mL vials of TMB 3 x 50 mL Bottles of Sample Buffer 3 x 15 mL vials of Dilution Buffer 3 x 0.5 mL vials of Vlla-AT Calibrator 3 x 0.5 mL vials of Vlla-AT Control 1 Plate Frame; 1 Adhesive Film 1 x 50 mL bottle of Washing Solution 00543US STA®-Liatest® FM 6 x 2 mL vials of Buffer Immuno-turbidimetric assay of Fibrin Monomer by STA® analyzers. 6 x 4 mL vials of Latex Microlatex particles coated with two different mouse monoclonal 90 tests \"">_!+

00544US STA®-FM Calibrator 2 x 1 mL vials of calibrator 1 A set of calibrator plasmas intended for calibration of 2 x 1 mL vials of calibrator 2 the immunoturbidimetric method. To be used with 00543US. 2 x 1 mL vials of calibrator 3 2 x 1 mL vials of calibrator 4 2 x 1 mL vials of calibrator 5 00545US STA®-FM Control 6 x 1 mL vials of control 1 Two plasmas intended for the quality control of 6 x 1 mL vials of control 2 the immunoturbidimetric method. To be used with 00543US.

00581 Liatest® C4b-BP 6 x 1 mL vials of Latex Quantitative determination of C4b-BP 6 x 4 mL vials of Buffer by Immuno-turbidimetric measurement, 60 tests.

00616 Asserachrom® TAFIa/TAFIai 3 x 2 Coated Strips Quantitative determination of TAFIa/TAFIai 3 x 8 mL vials of Anti-TAFIa/TAFIai-Peroxidase by ELISA method, 96 tests. 3 x 8 mL vials of TMB 3 x 50 mL Bottles of Dilution Buffer 1 x 50 mL Bottle of Washing Solution 3 x 0.5 mL vials of TAFIa/TAFIai Calibrator 3 x 0.5 mL vials of TAFIa/TAFIai Control 1 Plate Frame; 1 Plate Cover

00704US STA®-Rivaroxaban Calibrator 3 x 1 mL vials of Calibrator 1 Calibration plasmas for rivaroxaban measurement 3 x 1 mL vials of Calibrator 2 using chromogenic anti-Xa Method. 3 x 1 mL vials of Calibrator 3 3 x 1 mL vials of Calibrator 4

00706US STA®-Rivaroxaban Control 3 x 1 mL vials of Control 1 Control plasmas for rivaroxaban measurement 3 x 1 mL vials of Control 2 using chromogenic anti-Xa Method.

00851 Stachrom® Heparin Cofactor II 6 x 2 mL vials of Thrombin Chromogenic assay of heparin cofactor II activity, 60 tests. 6 x 2 mL vials of Substrate 1 x 15 mL bottle of Buffer

33 Section 18 Research Kits (continued) (Research Use only, not for diagnostic procedures)

CAT. NO. PRODUCT/ DESCRIPTION CONTENTS 00853 Stachrom® PAI 2 x 2 mL vials of Urokinase Chromogenic assay of plasminogen activator inhibitor activity, 20 tests. 2 x 2 mL vials of Plasminogen 2 x 2 mL vials of Substrate 2 x 0.5 mL vials of PAI Calibrator 1 2 x 0.5 mL vials of PAI Calibrator 2 2 x 0.5 mL vials of PAI Calibrator 3

00949US Asserachrom® PAI-1 3 x 2 Coated Strips Quantitative determination of plasminogen activator inhibitor-1 3 x 8 mL vials of Anti-PAI-1-Peroxidase Antigen (PAI-1) by ELISA method, 96 tests. 3 x 8 mL vials of TMB 3 x 50 mL bottles of Dilution Buffer 1 x 50 mL bottle of Washing Solution 3 x 2 mL vials of PAI-1 Calibrator 3 x 2 mL vials of PAI-1 Control 1 Plate Frame; 1 Plate Cover

00955 Asserachrom® VII:Ag 3 x 2 Coated Strips Quantitative determination of Factor VII:Ag 3 x 8 mL vials of Anti-VII:Ag Peroxidase by ELISA method, 96 tests. 3 x 8 mL vials of TMB 3 x 50 mL vials Dilution Buffer 1 x 50 mL vial Washing Solution 3 x 0.5 mL vials of F. VII:Ag Calibrator 3 x 0.5 mL vials of F. VII:Ag Control 1 Plate Frame 1 Plate Cover 00956 Asserachrom® X:Ag 3 x 2 Coated Strips Quantitative determination of Factor X:Ag 3 x 8 mL vials of Anti-X:Ag Peroxidase by ELISA method, 96 tests. 3 x 8 mL vials of TMB 3 x 50 mL vials Dilution Buffer 1 x 50 mL vial Washing Solution 3 x 0.5 mL vials of F. X:Ag Calibrator 3 x 0.5 mL vials of F. X:Ag Control 1 Plate Frame 1 Plate Cover 01004 Cy-Quant CD146 3 x 2 Coated Strips For the determination of soluble CD146 (sCD146, S-ENDO 1, MUC 18, 3 vials of Calibrator melanoma cell adhesion molecule) in plasma and serum, by ELISA 1 vial of Stop Solution method, 96 tests. 1 vial of TMB 1 vial of Washing solution 1 vial of Dilution buffer 1 vial of Anti CD146-peroxidase 1 vial of Control plasma 1 Plate Frame 01111 STA®-Apixaban Control 3 x 1 mL vials of Control 1 Control plasmas for apixaban measurement using chromogenic 3 x 1 mL vials of Control 2 anti-Xa Method.

01112 STA®-Apixaban Calibrator 3 x 1 mL vials of calibrator 1 Calibration plasmas for apixaban mesurement chromogenic 3 x 1 mL vials of calibrator 2 anti-Xa Method. 3 x 1 mL vials of calibrator 3 3 x 1 mL vials of calibrator 4 01138 Asserachrom® VWF: FVIIIB 3 x 2 Coated Strips Kit for the quantitative determination of the capacity of von Willebrand 3 x 8 mL vials of recombinant FVIII factor to bind to factor VIII (VWF:FVIIIB) by enzyme-linked 3 x 8 mL vials of Anti-FVIII-Peroxidase immunosorbent assay (ELISA), 96 tests. 3 x 8 mL vials of TMB 3 x 15 mL vials of Dilution Buffer 3 x 20 mL vials of Reconstitution Buffer 1 x 50 mL bottle of Washing Solution 3 x 2 mL vials of vWF:FVIIIB Calibrator 3 x 2 mL vials of vWF:FVIIIB Control 1 Plate Frame; 1 Plate Cover

34 Product Catalog 2015 Research Components Section 19 (Research Use only, not for diagnostic procedures)

CAT. NO. PRODUCT/ DESCRIPTION CONTENTS Puriﬁ ed Proteinsa

00392 Puriﬁ ed 2-GP1 100 μg

00461 Puriﬁ ed VWF 100 μg

00462 Puriﬁ ed Factor X !=$=>@!!)#

00463 Puriﬁ ed Heparin Cofactor II =$=>@!!)#

00519 Puriﬁ ed Fibrinogen 8 mg

00557 Puriﬁ ed Prothrombin =$=>@!!)#

00828 Puriﬁ ed APC !)#

00888 Puriﬁ ed AT III !)#

00896 Puriﬁ ed Thrombin 1000 NIH Units

00912 Puriﬁ ed Factor Xa !)#

Chromogenic Substratesb

00811 CBS 31.39 (Substrate for Factor Xa) $>+)

00873 CBS 34.47 (Substrate for Thrombin) $>+)

Venoms and Inhibitorsb

00823 Ecarin 1 vial, 50 Ecarin Units (EU)

00830 r-Hirudin 1 vial, 2,000 r-Hirudin Antithrombin Units (ATU)

b All chromogenic substrates, venoms and inhibitors are freeze-dried. 35 Abbreviations

ABBREVIATION NAME ABBREVIATION NAME 2-AP Alpha-2-Antiplasmin GPO Group Purchasing Organization ACA Anticardiolipin Antibodies GPV Glycoprotein V APA Antiphospholipid Antibody(ies) HBPM Héparines de bas poids moléculaire (French designation for LMWH) APC Activated Protein C HPIA Heparin-PF4 Induced Antibodies

APTT Activated Partial Thromboplastin Time LA Lupus Anticoagulants AT Antithrombin LMWH Low Molecular Weight Heparin AT:Act Antithrombin Activity N+ABN Normal and Abnormal AT:Ag Antithrombin Antigen N+P Normal and Pathologic

CaCl2 Calcium Chloride OPD Ortho-phenylenediamine DIC Disseminated Intravascular Coagulation PAI 1 Plasminogen Activator Inhibitor 1 DSI Diagnostica Stago Inc PC Protein C ELISA Enzyme-Linked Immunosorbent Assay PF4 Platelet Factor 4 Fib Fibrinogen PIVKA Protein Induced by Vitamin K Antagonists FDP Fibrinogen Degradation Products PNP Pooled Normal Plasma FII Factor II or Prothrombin PS Protein S FOB Free On Board PT Prothrombin Time FSE Field Service Engineer PTT-LA LA Sensitive APTT FV Factor V TAFI Thrombin Activable Fibrinolysis Inhibitor FVII Factor VII TFPI Tissue Factor Pathway Inhibitor FVIII Factor VIII TMB Tetra Methyl Benzidine FIX Factor IX TSS Technical Support Specialist FX Factor X TT Thrombin Time FXI Factor XI UFH Unfractionated Heparin FXII Factor XII VWD Von Willebrand Disease FM Fibrin Monomer VWF Von Willebrand Factor

36 Product Catalog 2015 H E M O S T A S I S tPA FDP D-Dimer

PAI-1 Plasminogen Plasmin Fibrin TM

Fibrinogen IIa

PC IIa

AT APC PS II

PS APC V AT Activated Va Xa Platelet vWF X

XI IXa VIIIa APC PS VIII

XIa IX

Activation pathways Inhibition pathways Coagulation VIIa AT PAI-1 AT Fibrinolysis Xa TFPI APC PS Xa TFPI TF

AT THE HEART OF HEMOSTASIS Terms and Conditions of Sale

FOR REAGENTS, DISPOSABLES & ACCESSORIES Deﬁnitions: Sequestering: Products:#> " ` Reagents to be sequestered (by storing a pre-established quantity of a in DSI’s Product catalog in force. single lot of Reagent) are determined by DSI based on Customer’s DSI: Diagnostica Stago, Inc., a Delaware corporation with its sequestering request. Sequestering will require a hard copy Purchase principal place of business at Five Century Drive, # % $% Parsippany, NJ 07054, the seller of the Products. including beginning and end dates. Customer: The person or entity purchasing the Products. First delivery of sequestered Reagents cannot be less than 30 days from the date of the sequestering request. Ordering Information: Please reference your Customer number when placing all orders. Returns: Customer may not return Reagents ordered in error. Returns will not be Orders are accepted by telephone or fax: accepted or a credit issued without prior approval and a Return Attn: Sales Administration Department Authorization Number assigned by a Sales Administration Phone: (800) 222-COAG (2624) Menu option 3 Representative. Please call (800) 222-COAG Menu option 3. Fax: (973) 426-9460 Two categories of returns will be accepted: Monday through Friday: 8:30 am to 5:00 pm 1) Products shipped in error by DSI, and 2) Analyzer parts, disposables, (Eastern Time) or accessories, ordered in error by Customer may be returned provided By mail, please refer all orders to: a Return Authorization number is assigned by a Sales Administration Diagnostica Stago, Inc. Representative, the item is returned in the original unopened packaging, Attn: Sales Administration Department and received undamaged. However, in category 2), Customer will be 330 Waterloo Valley Road charged a 35% restocking fee. Mount Olive NJ 07828 In order to receive replacement Product or credit, the following criteria Application: must be met: The problem must be reported within 30 working days from the date stated on the Product invoice; &% Returned Product must be in the same condition as it was received; No the purchase order placed by Customer or related correspondence. returns will be accepted after 30 days from the date on the Product `% > invoice. Please send all returns indicating the Return Authorization Conditions of Sale shall be null and void unless approved in writing by Number on the outside of the package to: DSI. The failure or delay of DSI to enforce any of these Terms and Diagnostica Stago, Inc. Conditions of Sale shall not be deemed to be a waiver by DSI of any Return’s Department +{&>&>" Distribution Warehouse of a Group Purchasing Organization (GPO) having a contract with DSI, 330 Waterloo Valley Road # $ & ? " Mount Olive, NJ 07828 interpreted as per the contract between said GPO and DSI in effect at the time of purchase. Limited Warranty: Payment: Each of the Products shall be free from defects in material and The prices for the Products are those indicated in DSI’s price lists in ?&{R effect at the time the order is placed by Customer. A $50.00 minimum the package when delivered by DSI. purchase is required. Terms of payment are net 30 days from the date Subject to DSI’s acceptance of the non-conformity of the Products of DSI’s invoice. Customer shall report any incorrect billing to DSI Sales delivered, the warranty for defective Products is strictly limited to the Administration within 15 days after the delivery of invoice. Customer replacement free of charge of the corresponding Products. #"{&%@> EXCEPT TO THE EXTENT OF THE LIMITED WARRANTY SPECIFICALLY paid by DSI on behalf of Customer. DSI will not bill third party providers SET FORTH IN THIS ARTICLE, AND NOTWITHSTANDING ANY for such payments. PROVISION TO THE CONTRARY CONTAINED HEREIN OR IN ANY DSI reserves the right, in addition to all other remedies available, at its OTHER DOCUMENT, NO WARRANTY OR GUARANTEE, EXPRESS OR sole discretion and without prior notice (i) to suspend deliveries of IMPLIED, INCLUDING ANY WARRANTY OF MERCHANTABILITY OR Products and to reject any new orders made unless and until payment FITNESS FOR A PARTICULAR PURPOSE OR USE, IS MADE. in full is made by Customer of all outstanding amounts due to DSI and (ii) to charge interest on past due amounts at the rate of one and one In no event shall DSI, its employees or its suppliers be liable for lost half percent (11/2%) per month until paid or the lesser maximum % > > > amount permitted by law. exemplary damages, irrespective of whether attributable to contract, Delivery: warranty, negligence, strict liability or otherwise. Products shall be delivered FOB Origin, freight prepaid and added to Governing Law – Venue: the invoice. Delivery of the Products shall be deemed to have occurred These Terms and Conditions of Sale shall be governed by and &=$ interpreted in accordance with, the laws of the State of New York carrier, or (ii) in case of an unsuccessful attempt at shipment, two applicable to contracts made and wholly performed in New York. All business days following the sending of notice to Customer stating that disputes arising out of or in connection with the order made under Products are at Customer’s disposal at DSI’s shipping point. these Terms and Conditions of Sale must be settled by one Arbitrator sitting in New York City, in accordance with the Commercial Arbitration Rules of the American Arbitration Association, and judgment upon the award rendered by the Arbitrator may be entered in any Court having jurisdiction over the parties.

38 Product Catalog 2015 Main Index

ITEM PAGE(S) ITEM PAGE(S) Anti-human GPVI, PE ...... 31 CD62P, clone LYP20, PE ...... 30 Anti-human GPVI purified ...... 31 CD62P, clone LYP20, purified ...... 30 Asserachrom® Anti-Prothrombin IgG, M ...... 32 Cellquant calibrator ...... 29 Asserachrom® D-Di ...... 15 Cellquant PNH ...... 29 Asserachrom® Free Protein S ...... 13 Ctl. Neg. lgG1 - FITC (2DNP2H11) ...... 30 Asserachrom® Free TFPI...... 32 Ctl. Neg. lgG1 - PE (2DNP2H11) ...... 30 Asserachrom® PAl- 1 ...... 34 Ctl. Neg. lgG1 - purified (2DNP2H11) ...... 30 Asserachrom® Protein C ...... 13 Ctl. Neg. lgG2a PE (2DNP16C12) ...... 31 Asserachrom® sEPCR ...... 32 Ctl. Neg. lgG2a purified (2DNP16C12) ...... 31 Asserachrom® Soluble GPV...... 32 Ctl. Neg. lgG2a - FITC (2DNP16C12) ...... 31 Asserachrom® Total Protein S...... 13 Ctl. Neg. lgG2b - FITC (2DNP14G5) ...... 31 Asserachrom® Total TFPI ...... 32 Ctl. Neg. lgG2b PE (2DNP14G5) ...... 31 Asserachrom® tPA ...... 16 Ctl. Neg. lgG2b purified (2DNP14G5) ...... 31 Asserachrom® VII:Ag ...... 31 D-Di Test® ...... 15 Asserachrom® VIII:Ag ...... 32 Dispensing Tip ...... 26 Asserachrom® VWF:Ag ...... 16 Ecarin Chromogenic Assay (ECA) ...... 27 Asserachrom® VWF:FVIIIB ...... 35 External Quality Assessment Program ...... 19 Asserachrom® X:Ag ...... 31 F.S. Test ...... 15 Asserachrom® ß-TG ...... 16 F.S. Test Unit...... 15 Asserachrom® HPIA (ELISA) ...... 12 FDP Plasma ...... 15 Asserachrom® IX:Ag ...... 11 FDP Plasma Buffer ...... 15 Asserachrom® PF4 ...... 16 FDP Plasma Latex ...... 15 Calibrated Automated Thrombogram® ...... 26 Fibrinogen, clone 9F9, FITC ...... 30 CBS 31.39 ...... 35 FluCa Kit ...... 26 CBS 34.47 ...... 35 FS/FDP Plasma Test Cards ...... 15 CD146, clone COM2F6, purified ...... 30 Halogen Lamp ...... 7 CD146, clone COM3D9, purified ...... 30 Internal Quality Control Peer Program ...... 19 CD146, clone COM5G6, purified ...... 30 Immulon Round Bottom plate, 2HB...... 26 CD146, clone COM7A4, Biotin ...... 30 Liatest® AT III ...... 12 CD146, clone COM7A4, FITC ...... 30 Liatest® C4b-BP ...... 33 CD146, clone COM7A4, purified ...... 30 Liatest® Protein S ...... 12 CD146, clone S-Endo 1, Biotin ...... 30 Megamix ...... 29 CD146, clone S-Endo 1, FITC ...... 30 Miscellaneous Parts ...... 8 CD146, clone S-Endo 1, PE ...... 30 MP Reagent ...... 26 CD146, clone S-Endo 1, purified ...... 30 PAlg kit ...... 29 CD32, clone 2B2, purified ...... 31 Platelet Calibrator ...... 29 CD36, clone 10.5, FITC ...... 30 Platelet GP Receptors ...... 29 CD36, clone 10.5, PE ...... 31 Platelet Gp Screen ...... 29 CD36, clone 10.5, purified ...... 30 Platelet gpllb/llla Occupancy ...... 29 CD41, clone PL2-49, FITC...... 30 Platelet VASP/P2Y12 ...... 29 CD41, clone PL2-49, PE...... 30 Polyethylene Glycol ...... 18 CD41, clone PL2-49, purified ...... 30 PPP Reagent ...... 26 CD42b, clone ALMA 19, FITC ...... 30 PPP Reagent High ...... 26 CD42b, clone ALMA 19, PE ...... 30 PPP Reagent Low ...... 26 CD42b, clone ALMA 19, purified ...... 30 PRP Reagent ...... 26 CD61, clone 4F8, FITC ...... 30 PTT-LA ...... 14 CD61, clone LYP18, FITC ...... 31 Purified ß2-GP1 ...... 35 CD61, clone LYP18, PE ...... 31 Purified APC ...... 35 CD61, clone LYP18, purified ...... 31 Purified AT III ...... 35 CD61, clone 4F8, purified ...... 30 Purified Factor X ...... 35 CD62P, clone LYP20, FITC ...... 30 Purified Factor Xa ...... 35 39 Main Index

ITEM PAGE(S) ITEM PAGE(S) Purified Fibrinogen ...... 35 STA®-Stachrom® AT III ...... 13 Purified Heparin Cofactor II ...... 35 STA®-Stachrom® Plasminogen ...... 16 Purified Thrombin ...... 35 STA®-Stachrom® Protein C ...... 13 Purified VWF ...... 35 STA®-Stachrom® TAFI ...... 33 r-Hirudin ...... 35 STA®-Staclot® DRVV Confirm ...... 14 Redquant PNH ...... 29 STA®-Staclot® DRVV Screen 2 ...... 14 STA®-Apixaban Calibrator ...... 34 STA®-Staclot® DRVV Screen 5 ...... 14 STA®-Apixaban Control ...... 34 STA®-Staclot® Protein C ...... 13 STA®-Rivaroxaban Calibrator...... 34 STA®-Staclot® Protein S ...... 13 STA®-Rivaroxaban Control ...... 34 STA®-System Control N + P ...... 17 STA®-C.K. Prest 5 ...... 10 STA®-Thrombin 10 ...... 10 ® ® STA -CaCl2 ...... 18 STA -Thrombin 2 ...... 10 STA®-Cleaner Solution ...... 18 STA®-Unicalibrator ...... 18 STA®-Coag Control N + ABN ...... 17 STA®-VWF:Ag Calibrator ...... 18 STA Compact Max® Coagulation System ...... 4 STA-R Evolution® Expert Series ...... 3 STA Compact Max® Coag System with Cap Piercing ...... 4 Hemostasis System STA®-Control LA 1 + 2 ...... 17 STA-R Evolution® Expert Series Hemostasis ...... 3 STA®-Deficient II ...... 11 System with Cap Piercing STA®-Deficient IX ...... 11 STA-R Evolution®, STA Compact Max® and ...... 7-8 STA®-Deficient V ...... 11 STA Satellite® Disposables and Accessories STA®-Deficient VII ...... 11 Stachrom® Heparin ...... 12 STA®-Deficient VIII ...... 11 Stachrom® Heparin Cofactor II ...... 34 STA®-Deficient X ...... 11 Stachrom® PAI ...... 34 STA®-Deficient XI ...... 11 Staclot® LA...... 14 STA®-Deficient XII ...... 11 Staclot® LA 20 ...... 14 STA®-Desorb U ...... 18 Staclot® VIIa-rTF ...... 33 STA®-Fibrinogen 5 ...... 10 STart® Disposables and Accessories...... 8 Stago Added Value on Request (SAVOR)...... 20 STart® Hemostasis Analyzer ...... 6 STA®-HBPM/LMWH Control ...... 17 Test cards for D-Di Test kit ...... 15 STA®-Hepanorm H...... 18 Thrombin Calibrator ...... 26 STA®-Hepanorm® HBPM/LMWH ...... 18 STA®-Heparin Control ...... 17 STA®-Liatest® Control N + P ...... 17 STA®-Liatest® D-Di ...... 15 STA®-Liatest® Free Protein S ...... 12 STA®-Liatest® VWF:Ag ...... 16 STA®-Multi Hep Calibrator ...... 18 STA®-Neoplastine ® CI 5 ...... 10 STA®-Neoplastine ® CI Plus 10 ...... 10 STA®-Neoplastine ® CI Plus 5 ...... 10 STA®-Owren-Koller Buffer...... 18 STA®-Procoag - PPL ...... 33 STA®-PTT Automate 5...... 10 STA®-Quality HBPM/LMWH...... 17 STA®-Reptilase ...... 10 STA®-Liquid Anti-Xa 4 ...... 12 STA®-Liquid Anti-Xa 8 ...... 12 STA® Satellite® Hemostasis System ...... 5 STA®-Stachrom® Antiplasmin ...... 16