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Bro Taf Formulary Since the Most Recent Version of the Formulary Was Posted on the WMIC Website

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Bro Taf Formulary Since the Most Recent Version of the Formulary Was Posted on the WMIC Website Formulary 3rd Edition - Update May 2010 This document includes all drug decisions made by the Medicines & Therapeutics Executive Committee up until April 2010. Dear Colleague This Formulary is the result of collaboration between the Bro Taf Localities Drug & Therapeutics Committee and the two Medicines and Therapeutics Executive Committees for North Bro Taf and Cardiff and the Vale. It has been produced at the Welsh Medicines Information Centre. This Update, produced in May 2010, includes drug decisions made since the last hard copy was printed in 2003. Each chapter is currently undergoing review by clinicians and pharmacists across the local area to enable us to produce a fully revised edition. In the meantime, please email us at the address below if you would like to comment or assist with the review process. Searching the Formulary The quickest way to access information from this pdf document is to use the “edit” option on the toolbar. Drop the menu down to “find on this page” and insert the drug name or other search word. Where possible we have included NICE guidance and CSM warnings. Please refer to the Summary of Product Characteristics for full prescribing information. If you download the formulary from the website, please remember that the formulary on the web will be updated frequently – at least every two months. Hence it will be necessary to download the updated version periodically. Internet access and updates This formulary is constantly being updated. During transition into the main text of the formulary, drugs will appear on an updates list which will be included as a separate section at the beginning of the document (see next page). Alternatively new additions may be viewed as a separate document by following the D&TC Prescribing Formularies/Additions List link from http://www.wmic.wales.nhs.uk/. Thank you to all clinicians and pharmacists who have provided advice on various sections, and to our clerical staff for their support. Any comments? We hope you will find the Bro Taf Localities Formularies useful and that they will help you to improve patient care. Your comments and suggestions for future updates would be welcome and may be made by contacting us at the addresses below: Contact Information Formulary Issues: Diana Fletcher, Senior Information & Formulary Pharmacist, E-mail: [email protected] Tel: (029) 2074 4298 (secretary) Bro Taf Localities Drug & Therapeutics Committee: Rowena McArtney, Professional Secretary, Senior Information Pharmacist, E-mail: [email protected] Tel: (029) 2074 4298 (secretary) Medicines Information Enquiries – Please contact your local centre Cardiff and Vale North Bro Taf Welsh Medicines Information Centre Medicines Information, Pharmacy Department University Hospital of Wales Royal Glamorgan Hospital Cardiff CF14 4XW Ynysmaerdy, Llantrisant CF72 8R Tel: (029) 2074 3877/2979 Tel: (01443) 443136 Recent Additions to the Bro Taf localities Prescribing Formularies The following changes have been made to the Bro Taf Formulary since the most recent version of the formulary was posted on the WMIC website. Approved products will be incorporated into the main text in due course. For decisions predating Update VIII, please refer to Update VII (attached below) and the main formulary documents. As always, the most recent updates supersede information in earlier updates & the main formularies. Please consult product literature before prescribing. Update VIII from January 2010 New results, issued following the DTC meeting in February and April 2010 and confirmed locally are shown in bold. Generic Name Drug & Therapeutics Committee Cwm Taf UHB Cardiff And Vale UHB Abbreviated Notes Prescribing Category Prescribing Category alitretinoin For the treatment of severe chronic hand Hospital Only Hospital Only eczema 26.2.10 NICE TA177 August 2009 DTC 24.9.09 Hospital Only in view of the fact that it is an oral retinoid and needs to be started and monitored by a Specialist. Allevyn First Line First Line First line DTC 11.2.10 Feb 2010 Allevyn Adhesive Specialist Initiated (use Second Line after Specialist Initiated Second Line Biatain). Second Line DTC 11.2.10 Feb 2010 Allevyn Adhesive Remove from the formulary (use Biatain Remove from Formulary Remove Sacral Adhesive.) Feb 2010 DTC 11.2.10 Allevyn cavity Remove. Cavicare is suitable alternative. Remove from Formulary remove DTC 11.2.10 Feb 2010 amiodarone AWMSG has finalised a Shared Care Change to Specialist Noted: Shared care protocol Prescribing template for amiodarone Initiated with Shared Care CV44 now on WMIC Previously posted on Prescribing arrangements. website Website 18.8.08 aspirin suppositories For acute treatment of stroke & TIA Second Line First line NICE CG68 July 08. First line. atomoxetine Diagnosis and management of ADHD in children, young people and adults. NICE CG72 September 2008 Note: This guidance includes Hospital Only until the Hospital Only until the adults. Shared Care Protocol is Shared Care Protocol is agreed. agreed. Atomoxetine: Hospital Only until the Shared Feb 2010 Care Protocol is agreed. DTC 11.2.10 brinzolamide/timolol Specialist Initiated Specialist Initiated Specialist Initiated (Azarga®) DTC 11.2.10 Feb 2010 April 2010 Carmellose eye drops Second Line Second Line Second Line (Optive®) DTC 11.2.10 Feb 2010 certolizumab pegol For the treatment of rheumatoid arthritis Decision awaited Hospital Only – the NICE TA186 February 2010. manufacturer provides DTC 22.4.19 Hospital Only – the the first 12 weeks of manufacturer provides the first 12 weeks of treatment free of charge treatment free of charge. cetuximab Cetuximab for the first-line treatment of Hospital Only Hospital Only metastatic colorectal cancer 26.2.10 NICE TA176 August 2009 DTC 24.9.09 Hospital Only Combiderm and Remove from Formulary Remove Remove Combiderm N DTC 24.9.09 dabigatran Venous thrombosis –reducing the risk of Awaiting confirmation Hospital Only venous thromboembolism (deep vein thrombosis and pulmonary embolism) in patients admitted to hospital. NICE CG92 Jan 2010. DTC 11.2.10 Generic Name Drug & Therapeutics Committee Cwm Taf UHB Cardiff And Vale UHB Abbreviated Notes Prescribing Category Prescribing Category darunavir (Prezista®) Co-administered with low dose ritonavir for Hospital Only Hospital Only the treatment of human immunodeficiency Feb 2010 virus (HIV)-1 infection in treatment naive patients. It is not suitable for shared care. AWMSG Advice 2009 December 2009 DTC 11.2.10 Hospital Only dexamfetamine Diagnosis and management of ADHD in Hospital Only Dexamfetamine is not children, young people and adults - See NICE Feb 2010 suitable for shared care CG72 September 2008. NB This guidance also and should remain includes adults DTC 13.11.08 Hospital Only Dexamfetamine is not suitable for shared care and should remain Hospital Only. DTC 11.2.10 diclofenac sodium 3% gel Diclofenac sodium 3% gel (Solaraze®) for the Change from Specialist Noted (Solaraze®) treatment of actinic keratosis Initiated to First Line suitable for initiation in Change from Specialist Initiated to First Line Previously posted on both primary and website DTC 10.7.08 secondary care 18.8.08 diltiazem rectal ointment Unlicensed “special” with widespread usage. To Second Line Noted 2% be added to Unlicensed Product appendix 2 of Previously posted on the formulary. DTC 12.2.09 website donepezil effervescent Added to the Formulary restricted to use in Hospital Only Hospital only patients who cannot tolerate conventional donepezil tablets. Previously posted on DTC 19.11.09 website dosulepin (previously For existing patients only – patients should Decision awaited. Existing patients only dothiepin) be reviewed if they are taking it for depression. NICE CG60 DTC 22.4.10 eslicarbazepine acetate Available for one year assessment Decision awaited Specialist Initiated for a (Zebinix®) period as a Specialist Initiated agent one year assessment DTC 22.4.10 period etravirine (Intelence®) Etravirine (Intelence®▼) is recommended as Hospital Only Hospital Only an option for use within NHS Wales for the 26.2.10 treatment of HIV-1 infected, antiretroviral treatment-experienced adults in combination with a boosted protease inhibitor and other antiretroviral medicinal products. Treatment should be initiated by a specialist in accordance with BHIVA guidelines. Not recommended for use as first line therapy. Not considered suitable for shared care. AWMSG Advice No 0609 August 2009 DTC 24.9.09 Evicel Hospital Only restricted to replacement of Hospital Only Hospital Only restricted to existing use of Quixil. Feb 2010 replacement of existing DTC 11.2.10 use of Quixil April 2010 fesoterodine Second Line agent. Decision awaited Decision deferred DTC 22.4.10 pending review of this class of drugs. Generic Name Drug & Therapeutics Committee Cwm Taf UHB Cardiff and Vale UHB Abbreviated Notes Prescribing Category Prescribing Category filgrastim (Ratiograstim®) Recommended as an option for use within NHS Hospital only Hospital Only Wales in the treatment of neutropenia. Please 26.2.10 see AWMSG Advice No 1609 August 2009 for full details. Not considered suitable for shared care. Biosimilars should be prescribed by brand name to avoid automatic substitution and ensure consistency in provision. DTC 24.9.09 glucose (Dextrose) liquid First Line First Line First Line (GlucoJuice®) DTC 19.11.09 26.2.10 glucose (Dextrose) First Line First Line First Line tablets (GlucoTabs®) DTC 19.11.09 26.2.10 hylan G-F 201 (Synvisc) Synvisc and Hyalgan should remain in the Hospital Only.16.6.08 Noted (Previously posted on formulary but be annotated to state that NICE website) CG59 February 2008 does not recommend their use in osteoarthritis. DTC 22.5.08 lidocaine 4% LMX4 Topical local anaesthetic cream. Available as For future consideration if Noted Hospital Only item for dermatologists in Cardiff request is received in Cwm (Previously posted on and Vale UHB for 6 month evaluation subject to Taf. website) provision of feedback. Indicators to be established prior to start of evaluation. DTC 19.11.09. liraglutide (Victoza®) Second Line adjunctive treatment for adults with Not to be made available Second Line in patients type 2 diabetes who are intolerant of exenatide.
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