ET LES Mammifferes

Bull. Org. mond. Sante 1953, 8, 535-589 Bull. World Hlth Org.

SELECT BIBLIOGRAPHY ON THE TOXICOLOGY OF PESTICIDES IN MAN AND MAMMALS

CHOIX DE RtFERENCES BIBLIOGRAPHIQUES CONCERNANT LES PROPRIETES TOXIQUES DES PESTICIDES * POUR L'HOMME ET LES MAMMIFfERES

This bibliography has been prepared from the reference sources available in the Library of the World Health Organization. Medical indexes and abstracting journals, and the bibliographies of many articles and books, were systematically scanned; the final selection and classification were undertaken by Dr. J. M. Barnes. As far as possible the titles of articles are given in the original language; in several cases, however, it has been impossible to verify these and the original title has been replaced by a translation, enclosed in square brackets.

Cette bibliographie a et preparee d'apres les differentes sources de documentation accessibles 'a la Bibliotheque de l'Organisation Mondiale de la Sante. Les index bibliographiques medicaux, les p6rio- diques analytiques, ainsi que les bibliographies de nombreux ouvrages et articles, ont ete systematiquement depouilles; le choix definitif et le classement ont et6 effectues par le Dr J. M. Barnes. Dans la mesure du possible, les titres des articles ont ete donnes dans la langue originale; dans quelques cas, cependant, il a ete impossible de verifier le titre original, qui a ete remplace par une traduction placee entre crochets.

Le terme <(pesticides >> est utilis6 ici pour d6signer les insecticides, les rodenticides, les herbicides, les fongicides et autres produits similaires.

194 - 535- 536 PESTICIDES

I. HAZARDS OF USE AND MANUFACTURE I. RISQUES INHERENTS A L'UTILISATION ET A LA FABRICATION

A. General A. Ge'ne'ralite'S 1. ABRAMS, H. K. Increased use of agricultural chemicals serious problem for industrial hygienists Industr. Hyg. Newslett. 1950, 10, No. 7, pp. 3-4, 16 2. ABRAMS, H. K. Public health aspects of agricultural chemicals In: American Chemical Society, Division of Agricultural and Food Chemistry, Agricultural control chemicals, Washington, D.C., 1950, pp. 52-55 3. AMERICAN MEDICAL ASSOCIATION, COMMITTEE ON PESTICIDES Health hazards of electric vaporizing devices for insecticides J. Amer. med. Ass. 1952, 149, 367-369 4. AMERICAN MEDICAL ASSOCIATION, COUNCIL ON FOODS AND NUTRITION Health hazards of pesticides J. Amer. med. Ass. 1948,137, 1603 5. ANDREWS, J. M. & SIMMONS, S. W. Developments in the use of the newer organic insecticides of public health importance Amer. J. publ. Hlth, 1948, 38, 613-631 6. ANWIKAR, A. K. The new organic insecticides of public health importance and their use Indian med. J. 1952, 45, 152-156 7. BISHOPP, F. C. Food, health and insecticides Agric. Chemic. 1951, 6, No. 2, pp. 38-40, 97-101 8. BRIESKORN, C. H. Influence of some new pest and weed control agents on our foods Z. Lebensmitt-Untersuch. 1951, 93, 292-298 9. BROWN, A. W. A. Insect control by chemicals, New York, 1951 10. BUSVINE, J. R. The use and abuse of insecticides Practitioner, 1951, 166, 179-188 11. CALIFORNIA STATE DEPARTMENT OF PUBLIC HEALTH Information on two of the newer insecticides Industr. Hyg. Newslett. 1949, 9, No. 2, p. 9 12. CAROZZI, L. Patologia degli agricoltori; le intossicazioni da insetticidi, disinfestanti, erbicidi Folia med. (Napoli), 1950, 33, 97-117 HAZARDS - RISQUES 537

13. CONFERENCE ON THERAPY Household poisonings: II Amer. J. Med. 1950, 8, 372-383 14. CONLEY, B. E. Why the American Medical Association is interested in the pesticide problem Pests, 1949, 17, No. 4, pp. 18-22 15. CONLEY, B. E. & WILSON, J. R. The physician's role in the pesticide problem In: American Chemical Society, Division of Agricultural and Food Chemistry, Agricultural control chemicals, Washington, D.C., 1950, pp. 61-64 16. COON, J. M. Hazards involved in pesticide application Agric. Chemic. 1951, 6, No. 3, pp. 53, 55 17. Danger from the newer insecticides Lancet, 1950, 1, 407-408 18. EICHLER, W. Vergiftungsgefahren mit neuzeitlichen Kontaktinsektiziden Dtsch. GesundhWes. 1949, 4, 1035-1042 19. FAIRHALL, L. T. The newer insecticides Industr. Hyg. Newslett. 1949, 9, No. 7, pp. 8-9, 16 20. FJELDDALEN, J. Are all insecticides poisonous to human beings ? Frukt og Baer, 1951, 4, 13-22 21. FREAR, D. E. H. Chemistry of insecticides, fungicides and pesticides, 2nd ed., New York, 1948 22. GIRARD, P. Les insecticides de synthese au point de vue de 1'hygiene et de la sante publique Rev. Cps Sante milit. 1950, 6, 105-142 23. GREAT BRITAIN, MINISTRY OF AGRICULTURE AND FISHERIES Toxic chemicals in agriculture. Report of the working party, London, 1951 24. HAYES, W. J., JR. Toxicology of insecticides CDC Bull. 1950, 9, 1-3 25. HAYES, W. J., JR. & SIMMONS, W. S. Benefits and hazards of insecticides to public health In: American Chemical Society, Division of Agricultural and Food Chemistry, Agricultural control chemicals, Washington, D.C., 1950, pp. 56-60 26. KAY, K. Health aspects of the new organic insecticides Rep. ent. Soc. Ont. 1950, 1951, 19-26 27. KING, F. C. The dangers of poisonous dusts and sprays Hlth & Soil, 1950, winter, 29-30 28. LEMMON, A. B. Hazards in use of new poisons Citrus Leaves, 1949, 29, No. 7, pp. 6-7, 28 538 PESTICIDES

29. LHOSTE, J. AperVu sur les insecticides organiques de synthese et sur leur emploi a' des fins sani- taires, Paris, Minist&re de la France d'Outre-Mer, 1948 30. Mocsy, J. A kontaktmergek Mag. dllotorv. Lap. 1946, No. 9, pp. 1-8 31. New hazards from agricultural chemicals J. Amer. med. Ass. 1950, 143, 1158-1159 32. New insecticides are dangerous Safety Review, 1949, 6, 10-11 33. Potential hazards of the newer insecticides Amer. J. Med. 1950, 8, 1-3 34. PRINCI, F. Environmental health aspects of certain agricultural pesticides Agric. Chemic. 1951, 6, No. 2, pp. 30-33 35. PRINCI, F. Toxicology and hazard record of the newer pesticides Agric. Chemic. 1952, 7, No. 1, pp. 44, 47, 97, 99, 101 36. RIPPER, W. E. Pest killers must not be man killers World Crops, 1950, 2, 474-477 37. SIMMONS, S. W. Health hazards of economic poisons and related substances Amer. J. trop. Med. 1951, 31, 514-518 38. SKINNER, J. B. Newer occupational diseases New Engl. J. Med. 1950, 243, 482-486 39. SRIVASTAVA, A. S. Hazards of insecticides and solvents to man Indian med. Rec. 1951, 71, 273-276, 313-317, 328-333 40. STARCKE, A. Insects and man Ent. Ber. (Amst.), 1952, 14, 3-6 41. THIEMANN, H. A. New insecticides and rodenticides and their health aspects Amer. Industr. Hyg. Ass. Quart. 1949, 10, 10-15 42. Toxic chemicals in agriculture Brit. med. J. 1951, 1, 628-630 43. Toxic weed-killers and insecticides Brit. med. J. 1951, 1, 639 44. WARD, J. C. Organic pesticides-new health hazards Arch. Induistr. Hyg. 1951, 4, 152-155 45. WEBSTER, R. L. New insecticides: their uses, limitations, and hazard to human health, Olympia, Wash., 1950 (Washington Agricultural Experiment Station, Circular No. 64) HAZARDS - RISQUES 539

46. WELLMAN, R. H. Synthetic chemicals for agriculture Chlem. & Ind. 1948, 62, 914-921; 63, 223-229 47. WILSON, J. R. Are pesticides making your food unsafe ? Hygiea, 1949, 27, 44-45, 66

B. Insecticides: DDT and Related Compounds B. Insecticides: DDT et Composes Voisins

48. ABAD GOMEZ, H. Inocuidad de la adici6n al agua potable de 1 p.p.m. de DDT para la erradicaci6n del 4 Aedes aegypti * Bo1. Ofic. sanit. pan-amer. 1951, 30, 330-337 49. ALESSANDRINI, M. E. Il p-diclorodifeniltricloroetano (DDT) R.C. Ist. sup. Sanita', 1946, 9, 133-148 50. CAMERON, G. R. Risks to man and animals from the use of 2,2-bis(p-chlorphenyl)-1,l,l,-trichlorethane (D.D.T.) Brit. med. Bull. 1945, 3, 233-235 51. GORDON, I. Occupational hazard of DDT spraying Brit. J. industr. Med. 1946, 3, 245-249 52. HOLDAWAY, F. G. Uses, dangers and shortcomings of DDT Plantat. Hlth, 1946, 10, No. 1, pp. 20-26 53. KILLIFFER, D. H. Is DDT poisonous ? Sci. Amer. 1946, 174, 5-7 54. LHOSTE, J. Le DDT est-il dangereux ? Nature (Paris), 1947, No. 3144, pp. 301-302 55. MILLER, S. E. DDT in medical practice Curr. med. Dig. 1946, July, 27-33 56. MtUHLENS, K. Ober die Bedeutung der Dichlor-diphenyl-trichlor-methylmethanpraparate als Arthropodengift in der Seuchenbekampfung unter Berijcksichtigung eigener Erfahrungen Dtsch. med. Wschr. 1946, 71, 164-169 57. MULLER, P., DOMENJOZ, R., WIESMANN, R. & BUXTORF, A. Dichlordiphenyltrichloroethan als Insektizid und seine Bedeutung fur die Human- und Veterinarhygiene Ergebn. Hyg. Bakt. 1949, 26, 5-138 540 PESTICIDES

58. Possible hazards from the use of DDT Amer. J. publ. Hlth, 1949, 39, 925-927 59. ROCHTCHIN, I. V. Voprosi gigieni truda v proizvodstve insektitsida DDT Gigiena, 1949, No. 8, pp. 21-26 60. STONE, T. T. & GLADSTONE, L. DDT (dichlorodiphenyltrichloroethane) J. Amer. med. Ass. 1951, 145, 1342 61. VON OETTINGEN, W. F. et al. Appraisal of the toxicity and potential dangers of DDT aerosol No. 304 (US Public Health Service. Project No. T.217, 1945) 62. WEST, T. F. & CAMPBELL, G. A. DDT and newer persistent insecticides, 2nd ed., London, 1950 63. ZEIN-EL-DINE, K. The insecticide DDT J. roy. Egypt. med. Ass. 1946, 29, 38-54

C. Insecticides: Aldrin, Chlordane, Dieldrin, and Toxaphene C. Insecticides: Aldrine, Chlordane, Dieldrine, et Toxaphene

64. PARKER, W. L. & BLACKER, J. H. Toxaphene, a chlorinated hydrocarbon with insecticidal properties, Newark, Del., 1947) (Delaware Agricultural Experiment Station, Bulletin No. 264)

D. Insecticides: Gamma-Isomer Benzene Hexachloride and its Isomers D. Insecticides: Hexachlorocyclohexane. Isomere Gamma et Autres Isomires 65. SLADE, R. E. The gamma isomer of hexachlorocyclohexane (Gammexane) Chem. & Ind. 1945, 64, 314-319

E. Insecticides: Organo-Phosphorus Compounds E. Insecticides: Composes Phosphores Organiques

66. ASHDOWN, D., DAHMS, R. G., RiDGWAY, W. 0. & SrILES, C. F. Hazards in the use of parathion for greenbug control J. econ. Ent. 1952, 45, 82-84 67. BIDSTRUP, P. L., DENZ, F. A., LANE, R. E., GOLDBLATT, M. W., DAVID, A. & NORMAN, L. G. Dangers of insecticides Brit. med. J. 1950, 2, 273-274 HAZARDS - RISQUES 541

68. CELICE, J., DEROBERT, C. & ALBAHARY, C. Les dangers de certains insecticides organo-phosphores anticholinesterasiques Bull. mid. (Paris), 1952, 66, 41-46 69. Dangers of insecticides Brit. med. J. 1950, 2, 273-274 70. DURAND-GASSELIN, L. Les esters phosphoriques Agriculture, 1950, 14, 115-117 71. Florida citizens warned of danger from parathion Industr. Hyg. Newslett. 1950, 10, 16 72. FLORIDA STATE BOARD OF HEALTH Exposure of pilots to parathion Industr. Hyg. Newslett. 1951, 11, 192 73. GRIFFITHS, J. T., STEARNS, C. R., JR. & THOMPSON, W. L. Parathion hazards encountered spraying citrus in Florida J. econ. Ent. 1951, 44, 160-163 74. GROB, D. Uses and hazards of the organic phosphate anticholinesterase compounds Ann. intern. Med. 1950, 32, 1229-1234 75. HALL, W. E. B. The industrial hazards of the organic phosphates and related insecticides, including parathion Ann. west. Med. Surg. 1951, 5, 1025-1027 76. INGRAM, F. R. Health hazards associated with the use of airplanes for dusting crops with parathion Amer. industr. Hyg. Ass. Quart. 1951, 12, 165-170 77. KAY, K. 0 Health problems of the new organic insecticides Canad. J. publ. Hlth, 1950, 41, 374-380 78. SPOLYAR, L. W. Dangers in the use of parathion as an insecticide Monthly Bull. Indiana Board Hlth, 1949, 52, 198 79. STEARNS, C. R., JR. et al. Concentration of parathion vapor in groves after spraying and effects of the vapor on small animals Citrus Mag. 1951, 13, No. 13, pp. 22-23 80. SUMERFORD, W. T. Chemistry and toxicity of some organofluorine insecticides In: American Chemical Society, Division of Agricultural and Food Chemistry, Agricultural control chemicals, Washington, D.C., 1950, pp. 160-174 81. THIODET, J. & MICHAUX, P. Risques et dangers dans la manipulation d'un nouvel insecticide organo-phospho- rique: le parathion ou S.N.P. Arch. Mal. prof. 1950, 11, 594-606 82. WARD, J. C. & DEWITT, J. B. Hazards associated with handling the new organic phosphates Pests, 1948, 16, No. 3, p. 34 542 PESTICIDES

F. Herbicides

83. ASSOULY, M. D6sherbants selectifs et substances de croissance. Aper9u technique. Effet pathologique sur l'homme au cours de la fabrication de l'ester du 24D Arch. Mal. prof. 1951, 12, 26-30 84. BIDSTRUP, P. L. Health hazards of dinitro-o-cresol Proc. 2nd Int. Congr. PI. Prot. London, 1949, 1951, 2, 23-25

H. Rodenticides

85. BAHR, L. 40 Jahre " Ratin "-Bazillus und "Ratin-System ", Kobenhavn, 1950 86. KALMBACH, E. R. "Ten-eighty ", a war-produced rodenticide Science, 1945, 102, 232-233 87. SCHMIDT, H. W. [Common chemical preparations for rat control; their production, composition, toxicity, and use] Seifensiederztg, 1947, 73, 93-94 88. SIMMONS, S. W. & NICHOLSON, H. P. Use of the rodenticides 1080 and Antu Pests, 1947, 15, No. 5, pp. 8, 10 89. WARD, J. C. Rodent control with 1080, ANTU, and other war-developed toxic agents Amer. J. publ. Hlth, 1946, 36, 1427-1431

H. PRECAUTIONS AND LEGISLATION II. PRECAUTIONS ET LEGISLATION

A. General A. Ge'neralite's

90. BISHOPP, F. C. Precautions in the use of insecticides for mosquito control Mosquito News, 1949, 9, 137-142 PRECAUTIONS - PRECAUTIONS 543

91. California protects by law workers exposed to agricultural chemicals Industr. Hyg. Newslett. 1951, 11, 34, 48 92. DAVID, A. Preventive medicine in weed and pest control Trans. Ass. industr. med. Offrs, 1951, 1, 14-25 93. DECKER, G. C. Legislative control of pesticide use J. econ. Ent. 1952, 45, 140-144 94. EVANS, R. B. Protection against agricultural dust hazards Agric. Chemic. 1951, 6, No. 12, pp. 34-35, 111, 113 95. FOULGER, J. H. Toxicological investigation by industry In: American Chemical Society, Division of Agricultural and Food Chemistry, Agricultural control chemicals, Washington, D.C., 1950, pp. 223-227 96. GREAT BRITAIN, MINISTRY OF AGRICULTURE AND FISHERIES Precautions in the use of insecticides, fungicides and weed-killers, London, 1950 97. HOLMES, E. L. & SALATHE, L. J. State and Municipal Health Department requirements for use of common residual insecticide sprays In: American Chemical Society, Division of Agricultural and Food Chemistry, Agricultural control chemicals, Washington, D.C., 1950, pp. 25-27 98. HUNTER, D. Devices for the protection of the worker against injury and disease. Part II Brit. med. J. 1950, 1, 506-5 12 99. LEMMON, A. B. Registration and labeling of economic poisons in California In: American Chemical Society, Division of Agricultural and Food Chemistry, Agricultural control chemicals, Washington, D.C., 1950, pp. 21-24 100. REED, W. G. Labeling requirements.for insecticides and other economic poisons under Federal Law In: American Chemical Society, Division of Agricultural and Food Chemistry, Agricultural control chemicals, Washington, D.C., 1950, pp. 17-20 101. TRUHAUT, R. Quelques problemes actuels d'hygi6ne et de sante publiques. II1. Probl6mes de toxicologie et d'hygiene industrielles Prod. pharm. 1952, 7, 219-223 102. UNITED STATES, DEPARTMENT OF AGRICULTURE INSECTICIDE DIVISION Regulations for the enforcement of the Federal Insecticide, Fungicide, and Roden- ticide Act. Interpretation No. 18 with respect to warning, caution and antidote statements required to appear on the labels of economic poisons, Washington, D.C., 1949 9 544 PESTICIDES

B. Insecticides: DDT and Related Compounds B. Insecticides: DDT et Composes Voisins

103. CALVERY, H. 0. Tolerance figure suggested for DDT A.LF. News, 1945, 3, No. 3, p. 3 104. Cox, A. J. Drug aspects of DDT Calif. Citrogr. 1944, 30, No. 1, pp. 6, 22-23, 26-27 105. HALL, G. E. State legislation (Massachusetts Law on DDT, 1513) J. Amer. med. Ass. 1946, 131, 1512-1516 106. POMMERT, R. DDT-caution Gladiolus Mag. 1947, 11, No. 3, p. 15 107. SROKA, K. H. Zur Vorbeugung von Gesundheitsgefahrdungen durch DDT Klin. Med. 1951, 6, 210-218

C. Insecticides: Aldrin, Chlordane, Dieldrin, and Toxaphene C. Insecticides: Aldrine, Chlordane, Dieldrine, et Toxaphbne

108. Recommendation for the use of chlordan Publ. Hlth News, 1950, 31, 139-140

D. Insecticides: Gamma-Isomer Benzene Hexachloride and its Isomers D. Insecticides: Hexachlorocyclohexane. Isomere Gamma et Autres Isomeres

109. BOGUSHEVSKII, S. M. & BURKATSKAYA, E. N. K. Voprosu o gigiene truda v selskomkhoziuistve pri rabotakh c geksakhloranom Gigiena, 1951, No. 4, pp. 30-34

E. Insecticides: Organo-Phosphorus Compounds E. Insecticides: Compose's Phosphores Organiques 110. BROWN, H. V. Device designed for automatic sampling of parathion during aircraft crop dusting Industr. Hyg. Newslett. 1951, 11, 35 TOXIC PROPERTIES - PROPRIETES TOXIQUES 545

111. CARMAN, G. E. & METCALF, R. L. Safe handling of organic phosphorus compounds ealif. Citrogr. 1951, 37, No. 1, pp. 6, 31-33 112. FRAZIER, R. Determination of parathion in air Industr. Hyg. Newslett. 1950, 10, No. 4, pp. 4-5 113. GRIFFITHS, J. T. et al. Toxicology ofparathion and other phosphatic insecticides and precautions for their use on citrus, Gainesville, Fla., 1951 (University of Florida Agricultural Experiment Station, Bulletin No. 479) 114. Health aspects in field application of parathion Industr. Hlth Bull., 1950, 5, 1-2 115. KING, H. How to use parathion safely Proc. Amer. Ass. econ. Ent. No. Cent. States Br. 1950, 5, 5-6 116. KING, H. How to use parathion and other insecticides East. Fruit Gr. 1951, 12, 22-24 117. Manufacturer cautious in handling parathion Industr. Hyg. Newslett. 1950, 10, No. 10, pp. 4-8 118. ORRELL, W. R. The safe handling of phosphorus insecticides with special reference to parathion Pitnt. Prot. Overseas Rev. 1950, 1, No. 4, pp. 9-13 119. PORTER, B. A. Safety in using parathion Mountaineer Grower, 1950, 20, No. 183, pp. 5-7, 10-11

F. Herbicides 120. BIDSTRUP, L., BONNELL, J. A. L. & HARVEY, D. G. Prevention of acute dinitro-ortho-cresol (D.N.O.C.) poisoning Lancet, 1952, 1, 794-795

m. TOXIC PROPERTIES m. PROPRItT1S TOXIQUJES A. General A. G&i6ralites 121. ANDERSEN, A. H., ANDERSEN, J. & FROST, J. Giftige ukrudt- og insektbekaempelses-midler Ugeskr. Laeg. 1952, 114, 885-889 546 PESTICIDES 122. BARNES, J. M. Health hazards from insecticides Brit. med. Bull. 1950, 7, 23-27 123. BARNES, J. M. Symposium on insecticides. VI. The action of some synthetic insecticides on mammals Trans. roy. Soc. trop. Med. Hyg. 1952, 46, 264-270 124. BATrE, E. G. & TURK, R. D. Toxicity of some synthetic insecticides to dogs J. econ. Ent. 1948, 41, 102-103 125. BERG, S. P. & MAIER, F. Zur Toxikologte einiger neuer Schadlingsbekampfungsmittel Dtsch Z. ges. gerichtl. Med. 1951, 40, 335-352 126. BETTINI, S. [Toxicity of insecticides for man and animals] Allevatore, 1950, 6, No. 42, p. 1; No. 43, p. 7 127. BirrINi, S. Studio sull'azione dei prodotti antiparassitari e della loro tossicitA sull'uomo e sugli animali R. C. Ist. sup. Sanit&, 1951, 14, 91-102 128. BORGMAN, R. Symptoms of poisoning by insecticides Vet. Med. 1951, 46, 237 129. BRISOU, J. Sur la toxicite des insecticides de contact Bull. Soc. Path. exot. 1949, 42, 379-383 130. DECOURT, P., DuPoux, R. & PELLOUX, A. Sur la toxicite des parasiticides et des molluscoldes pour les vertebres et les coeffi- cients de securite necessaires a leur emploi Bull. Soc. Path. exot. 1949, 42, 33-38 131. DELVAUX, E. L. & BERNIMOLIN, P. J. La toxicite pour les vertebres des principaux insecticides de synthese Meded. Landb. Hoogesch.-Gent, 1950, 15, 175-202 132. DRAIZE, J. H. et al. Toxicological investigations of compounds proposed for use as insect repellents. (a) Local and systemic effects following topical skin application. (b) Acute oral toxicity. (c) Pathological examination J. Pharmacol. 1949, 93, 26 133. HAMBLIN, D. 0. Toxicology of insecticides and fungicides Agric. Chemic. 1946, 1, 28-31 134. HATFIELD, I. Fly-control chemicals and toxicities Pests, 1949, 17, No. 6, pp. 9-14, 26 135. HAYES, W. J., JR. Toxicology of insecticides CDC Bull. 1950, 9, 1-3 TOXIC PROPERTIES - PROPRIE'TIS TOXIQUES 547 136. HINE, C. H. Pharmacology and toxicology of some important economic poisons In: American Chemical Society, Division of Agriculture and Food Chemistry, Agricultural control chemicals, Washington, D.C., 1950, pp. 39-42 137. HOFFMANN, I. & LEANDLE, L. Zur Wirkungsweise neuer insektizider Stoffe Arch. exp. Path. Pharmak. 1948, 205, 223-242 138. HOUGH, J. W. Important organic insecticides. Physiological effects and suggested treatment Industr. Hyg. Newslett. 1950, 10, 10-16 139. Insecticide storage in adipose tissue J. Amer. med. Ass. 1951, 145, 735-736 140. LE CLERC, E. L. et al. Toxicity ofinsecticides,fungicides, and herbicides, Washington, D.C., 1951 (mimeographed) 141. LEHMAN, A. J. The toxicology of the newer agricultural chemicals Bull. Ass. Fd Drug Off. 1948, 12, 82-89 142. LEHMAN, A. J. The toxicology of the newer insecticides Proceedings ofthe Fourth International Congresses on Tropical Medicine and Malaria, Washington, 1948, 2, 1713-1720 143. LEHMAN, A. J. Toxic actions of insecticides Amer. prof. Pharm. 1949, 15, 907-911, 938-939; Soap Blue Bk, 1949, pp., 173-175 144. LEHMAN, A. J. Pharmacological considerations of insecticides Bull. Ass. Fd Drug Off. 1949, 13, 65-70 145. LEHMAN, A. J. The major toxic actions of insecticides Bull. N.Y. Acad. Med. 1949, 25, 382-387 146. LEHMAN, A. J. The toxicology of the newer agricultural insecticides Pests, 1949, 17, No. 1, p. 7 147. LEMMON, A. B. The toxicity of insecticides to man and domestic animals Proc. 17th ann. Conf. Calif. Mosq. Ass. 1949, pp. 56-60 148. PHILIPS, F. S. Insecticides and rodenticides Fed. Proc. 1946, 5, 292-298 149. TAYLOR, H. Toxicity of insecticides to mammals and its evaluation Proc. 2nd Int. Congr. PI. Prot. 1949, 1951, 2, 428-432 150. TILEMANS, E. M. & DORMAL, S. Toxicit6 des produits phytopharmaceutiques envers l'homme et les animaux i sang chaud Parasitica, 1952, 8, 64-91 548 PESTICIDES

B. Insecticides: DDT and Related Compounds B. Insecticides: DDT et Composes Voisins 151. AMERICAN MEDICAL ASSOCIATION, COMMITTEE ON PESTICIDES Pharmacologic and toxicologic aspects of DDT (chlorophenothane U.S.P.) J. Amer. med. Ass. 1951, 145, 728-733 152. BETTINI, S. TossicitA cronica e contaminazioni degli alimenti da DDT R. C. Ist. sup. Sanit&, 1950, 13, 443-453; Riv. Parassit. 1949, 10, 265-270 153. CALVERY, H. O. DDT is poisonous Food Pack. 1945, 26, No. 5, pp. 61-62 154. CALVERY, H. O. & NEAL, P. A. The toxicity of DDT, solvents, emulsifiers, activators, and other adjuvants mentioned in this report, Washington, D.C. (U.S. Department of Agriculture, Miscellaneous Publication 606) 155. CHARBONNIER, D. Toxicite du DDT, Paris, 1949 (These) 156. DEEDERER, C. DDT toxicity Med. Rec. (N.Y.), 1948, 161, 216-220 157. Further results with DDT Brit. med. J. 1945, 2, 260 158. HOFFMANN, C. H. & LINDUSKA, J. P. Some considerations of the biological effects of DDT Sci. Monthly (Wash.), 1949, 69, 104-114. 159. HOFFMANN, C. H. & LINDUSKA, J. P. Alcune considerazioni sugli effetti biologici del DDT Ann. Igiene, 1950, 60, 88-102 160. LXUGER, P. et al. Mechanism ofintoxication ofDDT insecticides in insects and warm-blooded animals, New York, 1946 161. LORY, R., CHARTIER, P. & SERREAU, J. P. Sur quelques conditions de toxicite du DDT Ann. pharm. franc. 1949, 7, 101-104 162. NMAL, P. A. & VON OETTINGEN, W. F. The toxicity and potential dangers of DDT to humans and warm-blooded animals Med. Ann. Distr. Columbia, 1946, 15, 15-19 163. PLUMMER, P. J. G. Toxicity of DDT for laboratory and domestic animals Pests, 1946, 14, No. 2, p. 28 164. PRILL, E. A., HARTZELL, A. & ARTHUR, J. M. Insecticidal activity of some alkoxy analogs of DDT Science, 1945, 101, 464465 TOXIC PROPERTIES - PROPRlmTmS TOXIQUES 549

165. ROBERTS, A. Observations on the toxicity of DDT Practitioner, 1950, 164, 258-260 166. TELFORD, H. S. DDT toxicity Soap (N.Y.), 1945, 21, No. 12, pp. 161, 163, 167, 169 167. TOBIAS, J. M., KOLLROS, J. J. & SAVIT, J. Relation of absorbability to the comparative toxicity of DDT for insects and mammals J. Pharmacol. 1946, 86, 287-293 168. Toxicite du dichlor-diph6nyl-trichlorethane Med. trop. 1950, 10, 135-136 169. Toxicity of DDT Brit. med. J. 1945, 1, 338 170. Toxicity of DDT Brit. med. J. 1946, 1, 398 171. UNITED STATES, NATIONAL RESEARCH COUNCIL Conference on the toxicity of DDT, Washington, D.C., 1946 172. UNITED STATES, PUBLIC HEALTH SERVICE Statement on the toxicity of DDT J. Amer. med. Ass. 1949, 139, 1285 173. VELBINGER, H. H. Beitrag zur Toxikologie des "DDT "-Wirkstoffes Dichlor-diphenyltrichlormethyl- methan Pharmazie, 1947, 2, 268-274 174. VITTE, G. Sur la toxicit6 du DDT Bull. Soc. Pharm. Bordeaux, 1945, 83, No. 2, pp. 31-33

C. Insecticides Aldrin, Chlordane, Dieldrin, and Toxaphene C. Insecticides: Aldrine, Chlordane, Dieldrine, et Toxaphine 175. Aldrin and dieldrin poisoning J. Amer. med. Ass. 1951, 146, 378-379 176. RADELEFF, R. D. Chlordane poisoning: symptomatology and pathology Vet. Med. 1948, 43, 342-347 177. ROARK, R. C. A digest of information on chlordan, Washington, D.C., 1951 (U.S. Department of Agriculture, Bureau of Entomology, Plant Quarantine, E-817) 178. WITHERUP, S. Toxicological study of chlordan in aerosols Proceedings of the Chemical Specialities Manufacturers' Association, 1950, June, 67-70, 86-88 550 PESTICIDES

D. Insecticides: Gamma-Isomer Benzene Hexachloride and its Isomers D. Insecticides: Hexachlorocyclohexane. Isomere Gamma et Autres Isom6res (See also references 149, 152) (Voir aussi references 149, 152) 179. AMERICAN MEDICAL ASSOCIATION, COMMITTEE ON PESTICIDES Toxic effects of technical benzene hexachloride and its principal isomers J. Amer. med. Ass. 1951, 147, 571-574 180. GEISSLER, H. Uber Schaden im Anschluss an die Verwendung in Hexachlorcyclohexan- Praparaten und ilber die Vermeidung solcher Schaden Dtsch. tierdrztl. Wschr. 1951, 58, 97-98 181. GUILHON, J. Recherches sur les proprietes insecticides et sur la toxicite de l'hexachlorocyclohexane C.R. Acad. Agric. Fr. 1946. 32, 158-164 182. GUILHON, J. Propri6tes insecticides et toxicite des derives soufr6s de 1'hexachlorocyclohexane C. R. Acad. Agric. Fr. 1947, 33, 101-103 183. HEPDING, L. Ober eine einfache Priifungsmethodik und die Anwendungsbreite des y-hexachlor- zyklohexans Zbl. Bakt., l. Abt. Orig. 1949, 154, 226-230 184. KLOSA, J. Zur Toxikologie der Hexachlorocyclohexane Pharmazie, 1950, 5, 615-616 185. KWOCZEK, J. Uber die Toxizitat der DDT- und Hexachlorzyklohexanpraparate Med. Wschr. 1950, 4, 25-28 186. M ELTZER, J. Eigenschappen en giftigheid van hexachloorcyclohexaan Tijdschr. PlZiekt. 1950, 56, 101-148 187. MONCHE, J. & VIDAL-SIRILLA, S. Sobre la toxicidad de los hexaclorociclohexanos Rev. esp. Fisiol. 1950, 6, 1-4 188. PHILIPPOT, E. & DALLEMAGNE, M. J. La toxicite du gammexane Experientia (Basel), 1947, 3, 118 189. RIEMSCHNEIDER, R. Toxicology of hexachlorocyclohexane Suddtsch. ApothZtg, 1950, 90, 318-320 190. RULLIER, J. L'hexachlorocyclohexane. ProprikteJs physiques et toxicologiques. Principales appli- cations, Paris, 1948 (These) 191. Toxic effects of technical benzene hexachloride and its principal isomers J. Amer. med. Ass. 1951, 147, 571-574 TOXIC PROPERTIES PROPRIETES TOXIQUES 551

192. VELBINGER, H. H. Uber die unterschiedliche Wirkung der neuzeitlichen "Insektizide" DDT, gam- mexan und E605 Pharmazie, 1949, 4, 165-176

E. Insecticides: Organo-Phosphorus Compounds E. Insecticides: Composes Phosphores Organiques (See also reference 152) (Voir aussi reference 152) 193. ABRAMS, H. K. & LEONARD, A. R. Toxicology of organic phosphate insecticides Calif. Med. 1950, 73, 183-186 194. ALDRIDGE, W. N. & BARNES, J. M. Some problems in assessing the toxicity of the organo-phosphorus insecticides towards mammals Nature (Lond.), 1952, 169, 345-347 195. AMERICAN MEDICAL ASSOCIATION, COMMITTEE ON PESTICIDES Pharmacology and toxicology of certain organic phosphorus insecticides J. Amer. med. Ass. 1950, 144, 104-108 196. BARNES, J. M. The toxicity of the new organic phosphorus insecticides towards mammals Proc. 2nd Int. Congr. PI. Prot. 1949, 1951, 2, 14-15 197. BIDSTRUP, P. L. Poisoning by organic phosphorus insecticides Brit. med. J. 1950, 2, 548-551 198. DESOILLE, H. et al. Le thiophosphate de di6thylparanitroph6nyl, poison des cholinesterases Arch. Mal. prof. 1951, 12, 389-398 199. GROB, D. The anticholinesterase activity in vitro of the insecticide parathion (p-nitrophenyl diethyl thionophosphate) Bull. Johns Hopk. Hosp. 1950, 87, 95-105 200. HAGAN, E. C. & WOODARD, G. Toxicological properties of hexaethyl tetraphosphate Fed. Proc. 1947, 6, 335 201. Hexaethyl tetraphosphate J. Amer. med. Ass. 1947, 134, 742, 1516 202. KOELLE, G. B. & GILMAN, A. Anticholinesterase drugs Pharmacol. Rev. 1949, 1, 166-216 203. Louis, R. Ist das E 605 tatsachlich so giftig ? Obstbau, 1951, 70, 10-11 204. MANGUN, G. H. & DuBoIs, K. P. Toxicity and mechanism of action of tetraethyl pyrophosphate Fed. Proc. 1947, 6, 353-354 552 PESTICIDES 205. MisEs, R. Contribution t l'#tude de l'utilisation et de la toxicitg des esters phosphoriques, Paris, 1951 (These) 206. SALLE, J. Sur la toxicite d'un insecticide: le thiophosphate de diethyle et de paranitrophenyle (thiophos) pour les animaux superieurs et l'homme Rev. vct. milit. 1950, 2, 145-151 207. SPINDLER, M. Ober Diathyl-p-nitrophenylthiophosphat, eim neues Schadlingsbekampfungsmittel Praxis, 1949, 38, 936-939 208. TASCHEN, B. & WIRRIGER, W. E-605 in der Praxis und im Tierversuch Dtsch. med. Wschr. 1950, 75, 1478-1479 209. VELBINGER, H. Zur Kenntnis der Wirkungsweise von organischen Phosphorverbindungen als Insektizide Proc. 8th Int. Congr. Ent., 1948, 1950, pp. 953-957

F. Herbicides 210. SCHMIDT, H. W. [Action of dinitro-o-cresol on plants, animals, and man] Pharm. Zentralh. 1947, 86, 167-170

G. Fungicides G. Fongicides

21 1. Toxicity of insecticides: "P.M.4" Brit. med. J. 1950, 2, 1127

H. Rodenticides 212. DuBois, K. P. New rodenticidal compounds J. Amer. pharm. Ass. 1948, 37, 307-310 213. GEERLING, M. C. Nieuwe rodenticiden Chem. Weekbl. 1949, 45, 320-321 214. GIRARD, P. Nouveaux produits raticides Ann. Hyg. publ. (Paris), 1949, 27, 195-206 215. KRIEGER, C. H. Compound 42 Pests, 1949, 17, No. 5, pp. 24-28 EFFECTS ON MAN - EFFETS SUR L'HOMME 553

216. MUNCH, J. C. ANTU Soap (N.Y.), 1947, 23, 4, 147, 149, 169 217. RICHTER, C. P. The development and use of alpha-naphthyl thiourea (ANTU) as a rat poison J. Amer. med. Ass. 1945, 129, 927-931 218. WILLIAMS, A. T. Sodium fluoroacetate poisoning Hosp. Cps Quart. 1948, 21, 16-18

IV. EFFECTS ON MAN IV. EFETS SUR L'HOMME

A. General A. Generalites

219. GOLDMAN, L. Dermatologic aspects of insect repellents and toxicants Aidh. Derm. Syph. (Chicago), 1950, 62, 245-260 220. Laboratory tests for agricultural workers Brit. med. J. 1952, 1, 1014-1015 221. PATrON, T. E., JR. & FAVORITE, F. G. Human toxicological aspects of the insecticide and insect repellent development program of the Department of the Army Proc. N. J. Mosq. Ext. Ass. 1951, 38, 50-54 222. SIMMONS, S. W. & HAYES, W. J., JR. Relative toxicity of insecticides Soap (N.Y.), 1951, 27, No. 12, pp. 148-150 223. UNITED STATES, PUBLIC HEALTH SERVICE, COMMUNICABLE DISEASE CENTRE Clinical memoranda on economic poisons (mimeographed)

B. Insecticides: DDT and Related Compounds B. Insecticides: DDT et Composes Voisins

224. ANDERSON, A. & KHORRAM, M. A. Exposure to DDT Brit. med. J. 1948, 1, 1132-1134 554 PESTICIDES 225. ANGLEY, J. C. Toxicity of DDT in kerosene Air Surg. Bull. 1945, 2, 77 226. BALABAN, I. E. DDT poisoning Brit. med. J. 1946, 1, 147 227. BIDEN-STEELE, K. & STUCKEY, R. E. Poisoning by DDT emulsion. Report of a fatal case Lancet, 1946, 2, 235-236 228. BISKIND, M. S. DDT poisoning and the elusive " virus X" Amer. J. dig. Dis. 1949, 16, 79-84 229. BISKIND, M. S. DDT poisoning a serious public health menace Amer. J. dig. Dis. 1949, 16, 73 230. BISKIND, M. S. Statement on clinical intoxication from DDT and other new insecticides J. Insur. Med. 1951, 6, 5-12 231. BISKIND, M. S. & BIEBER, I. DDT poisoning-a new syndrome with neuro-psychiatric manifestations Amer. J. Psychother. 1949, 3, 261-270 232. BUXTON, P. A. The use of the new insecticide DDT in relation to the problem of tropical medicine Trans. roy. Soc. trop. med. Hyg. 1945, 38, 367U400 233. CAMPBELL, A. M. G. DDT poisoning in man. A suspected case Lancet, 1949, 2, 1178 234. CASE, R. A. M. Toxic effects of 2,2-bis(p-chlorphenyl)-l,1,1-trichlorethane (DDT) in man Brit. med. J. 1945, 2, 842-845 235. CHIT THOUNG, U. Poisonous effects of DDT on humans Indian med. Gaz. 1946, 81, 432 236. CORBO, S. La mortalitk infantile per malattie intestinali in rapporto con l'irrorazione di DDT e octaklor Arch. ital. Pediat. 1949, 13, 261-272 237. CSEH FIRTOS, S. & DE JONG, J. C. M. Gunstige uitkomsten van DDT-toepassing Ned. T. Geneesk. 1950, 90, 1105-1110 238. CUNNINGHAM, R. E. & HILL, F. S. Convulsions and deafness foUowing ingestion of DDT Pediatrics, 1952, 9, 745-747 239. DANGERFIELD, W. G. Toxicity of DDT to man Brit. med. J. 1946, 1, 27 EFFECTS ON MAN - EFFETS SUR L'HOMME 555

240. FRANCONE, M. P., MARIANI, F. H. A. & DEMARE, C. Clinica de la intoxicaci6n por DDT Pren. med. argent. 1951, 38, 2166-2170 241. FRANCONE, M. P., MARIANI, F. H. A. & DEMARE, C. Toxicologia del DDT Rev. Asoc. med. argent. 1951, 65, 381-390 242. GARRETr, R. M. Toxicity of DDT for man J. med. Ass. Ala, 1947, 17, 74 243. HIGGINS, E. L. & KINDEL, D. J. Exfoliatric dermatitis from contact with DDT J. invest. Derm. 1949, 12, 207-209 244. HILL, K. R. DDT poisoning Brit. med. J. 1946, 1, 255 245. HILL, K. R. & ROBINSON, G. A fatal case of DDT poisoning in a child, with an account of two accidental deaths in dogs Brit. med. J. 1945, 2, 845-847 246. HILL, W. R. & DAMIANI, C. R. Death following exposure to DDT New England J. Med. 1946, 235, 897-899 247. HOLLANDER, L. Dermatitis caused by DDT Arch. Derm. Syph. (Chicago), 1950, 62, 66-68 248. HOWELL, D. E. A case of DDT storage in human fat Proc. Okla. Acad. Sci. 1948, 29, 31-32 249. Human death attributed to DDT J. Amer. med. Ass. 1946, 132, 160 250. JUDE, A. & GIRARD, P. Toxicite du DDT-intoxication collective par ingestion accidentelle Ann, Med. leg. 1949, 29, 209-213 251. KARPINSKI, F. E., JR. Purpura following exposure to DDT J. Pediat. 1950, 37, 373-379 252. KLINGEMANN, H. Die DDT-Vergiftung irztl. Wschr. 1949, 4, 465469 253. LAUG, E. P., KUNZE, F. M. & PRICKETT, C. S. Occurrence of DDT in human fat and milk Arch. industr. Hyg. 1951, 3, 245-246 254. LAUG, E. P., PRICKEFf, C. S. & KUNZE, F. M. Survey analysis of human milk and fat for DDT content Fed. Proc. 1950, 9, 294-295 556 PESTICIDES

255. LAZAR, T. DDT pancakes Brit. med. J. 1946, 1, 932 256. LEIDER, M. Allergic eczematous contact-type dermatitis caused by DDT J. invest. Derm. 1947, 8, 125-126 257. MACKERRAS, I. M. & WEST, R. F. K. " DDT " poisoning in man Med. J. Aust. 1946, 1, 400-401 258. MARSHALL, J. Contact dermatitis due to DDT S. Afr. med. J. 1950, 24, 300-301 259. MERCK, R. Ein angeblicher Fall von DDT-Vergiftung Stddtehygiene, 1951, 2, 258 260. NAEVESTAD, R. Forgiftning med DDT-pulver og et par andre forgiftningstilfelle T. norske Laegeforen, 1947, 67, 261-263 261. NEAL, P. A. et al. The excretion of DDT (2,2-bis-p-chlorophenyl)-1,1,1-trichlorethane in man together with clinical observations Publ. Hlth Rep. (Wash.), 1946, 61, 403-409 262. NIEDELMAN, M. L. Contact dermatitis due to DDT: report of a case Occup. Med. 1946, 1, 391-395 263. NIKITIN, P. I. [Toxicity of DDT dust to man] Gigiena, 1950, No. 6, pp. 47-48 264. PIEIDROLA GIL, G. Un problema de suma actualidad e importancia: la toxicidad del diclorodifenil triclorometilmetano (DDT) para el hombre Med. colon. 1949, 14, 427-433 265. PIEIDROLA GIL, G. & FERNANDEZ MIR6N, B. Investigaciones acerca de la toxicidad del DDT para el hombre Med. colon. 1949, 14, 459-470 266. PLICHET, A. Le D.D.T. serait-il responsable de certaines gastro-entkrites ? Presse meid. 1949, 57, 1121-1122 267. PRATr-THOMAS, H. R. & WARING, J. I. DDT poisoning J. Amer. med. Ass. 1946, 131, 1384 268. REINGOLD, I. M. & LASKY, I. I. Acute fatal poisoning following ingestion of a solution of DDT Ann. int. Med. 1947, 26, 945-947 269. ROMANZI, C. A. Sui possibili danni alla salute dell'uomo derivanti dall'uso come insetticida del dicloro-difeniltricloroetano (DDT) Igiene mod. 1946, 39, 129-136 EFFECTS ON MAN - EFFETS SUR L'HOMME 557

270. SAUTERAUD, A. Action d'une solution a 5 % de dichlorodiphenyl-trichloro6thane (DDT) sur l'organisme de l'enfant Ann. Med. leg. 1947, 27, 261-262 271. SCHMIDT, H. W. DDT-Vergiftung bei 1500 mg Reinwirkstoff p.o. in oliger Emulsion Wien. med. Wschr. 1952, 102, 152 272. SEGRE, G. Sulla tossicita della DDT nell'uomo Minerva med. (Torino), 1947, 38, 224-226 273. SMITH, M. I. Accidental ingestion. of DDT, with a note on its metabolism in man J. Amer. med. Ass. 1946, 131, 519-520 274. SMITH, N. J. Death following accidental ingestion of DDT J. Amer. med. Ass. 1948, 136, 469-471 275. SMITSKAMP, H. Intoxicatie door DDT-Petroleum oplossingen Med. Maandbl. 1948, 384-388 276. STAMMERS, F. M. G. & WHITFIELD, F. G. S. Toxicity of DDT to man Nature (Lond.), 1946, 157, 658 277. STAMMERS, F. M. G. & WHITFIELD, F. G. S. The toxicity of DDT to men and animals Bull. ent. Res. 1947, 38, 1-73 278. STRYKER, G. V. & GODFROY, B. Dermatitis resulting from exposure to DDT: preliminary report J. Mo. med. Ass. 1946, 43, 384-386 279. TAYLOR, E. L. Danger of inunction with DDT Lancet, 1945, 2, 320 280. VELBINGER, H. H. Zur Frage der DDT-Toxizitdit fur Menschen Dtsch. GesundhWes. 1947, 11, 355-358 281. WESTERFIELD, C. Use of DDT in medicine-review Vet. Med. 1946, 41, 355-360 282. WIGGLESWORTH, V. B. A case of DDT poisoning in man Brit. med. J. 1945, 1, 517 283. WRIGHT, C. S., DOAN, C. A. & HAYNIE, H. C. Agranulocytosis occurring after exposure to a DDT pyrethrum aerosol bomb Amer. J. Med. 1946, 1, 562-567 284. YIN-CH'ANG CHIN & CHI-HSUjEH T'ANr The effect of DDT on cutaneous sensations in man Science, 1946, 103, 654 558 PESTICIDES

C. Insecticides: Aldrin, Chlordane, Dieldrin, and Toxaphene C. Insecticides: Aldrine, Chlordane, Dieldrine et Toxaphene 285. PRINCI, F. & SPURBECK, G. H. A study of workers exposed to the insecticides chlordan, aldrin, dieldrin Arch. industr. Hyg. 1951, 3, 64-72 286. SPIOTTA, J. Aldrin poisoning in man: report of a case Arch. industr. Hyg. 1951, 4, 560-566

D. Insecticides: Gamma-Isomer Benzene Hexachloride and its Isomers D. Insecticides: Hexachlorocyclohexane. Isomire Gamma et Autres Isom6res 287. BREDE, H. D. Vermexan, ein Gamma-Hexachlorcyclohexanpraparat als Anthelminticum Klin. Wschr. 1949, 27, 755 288. ENDREJAT, E. Olber Unfalle nach Schafbadungen in Gamma-hexan-Mitteln Tierdrzt. Umsch. 1950, No. 9-10, p. 164 289. FRANCONE, M. P. & CHENA, W. Dermatosis profesional por hexaclorociclohexano Rev. Asoc. m6d. argent. 1950, 64, 187-191 290. GRAEVE, K. & HERRNRING, G. tber die Anwendung der Gamma-Isomere des Hexachlorcyclohexan als Anthel- minticum Klin. Wschr. 1949, 27. 318 291. GRAEVE, K. & HERRNRING, G. Toxische Wirkungen des Gamma-Hexachlorcyclohexan bei seiner Anwendung als Anthelminthicum am Menschen Klin. Wschr. 1950, 28, 622-623 292. GRAEVE, K. & HERRNRING, G. Uber die Toxizitat des Gamma-Hexachlorcyclohexan Arch. int. Pharmacodyn. 1951, 85, 64-72 293. HALPERN, L. K., WOOLDRIDGE, W. E. & WEISS, R. S. Appraisal of the toxicity of the gamma isomer of hexachlorocyclohexane in clinical usage Arch. Derm. Syph. (Chicago), 1950, 62, 648-650 294. HORTON, R. G., KAREL, L. & CHADWICK, L. E. Toxicity of y-benzene hexachloride in clothing Science, 1948, 107, 246-247 295. LENDLE, L. & SCHNEIDER, H.-H. Olber die Eignung des Insektizids Hexachlorcyklohexan als Oxyurenmittel Arch. exp. Path. Pharmak. 1950, 210, 119-136 EFFECTS ON MAN - EFFETS SUR L'HOMME 559

296. LENDLE, L. & SCHNEIDER, H.-H. Zur Frage der Giftigkeit des Insectizids HCC als Oxyurenmittel Klin. Wschr. 1951, 29, 388-389 297. MOBBS, R. F. Toxicity of hexachlorocyclohexane in scabies J. Amer. med. Ass. 1948, 138, 1253 298. MOBBS, R. F. Hexachlorocyclohexane in scabies J. Amer. med. Ass. 1949, 139, 1224 299. MOTTA, L. A. C.-R. CAYOLLA DA Um caso de provavel intoxicagao humana pelo hexacloreto de benzeno (B.H.C.) An. Inst. Med. trop. (Lisboa), 1950, 7, 455-476 300. SCHNEIDER, H.-H. Hexachlorcyclohexan (HCC) als Oxyurenmittel Klin. Wschr. 1950, 28, 104

E. Insecticides: Organo-Phosphorus Compounds E. Insecticides : Composes Phosphores Organiques 301. ANDERSEN, A. H. & JERSILD, T. Poisoning by diethylparanitrophenylthiophosphate Acta pharmacol. 1949, 5, 129-134 302. BARNES, J. M. & DAVIES, D. R. Blood cholinesterase levels in workers exposed to organo-phosphorus insecticides Brit. med. J. 1951, 2, 816-819 303. BRAUER, R. W. Inhibition of the cholinesterase activity of human blood plasma and erythrocyte stromata by alkylated phosphorus compounds J. Pharmacol. 1948, 92, 162-172 304. BRAUER, R. W., HODGE, H. C. & RAVIN, H. A. The inhibition of the cholinesterase activity of human and canine blood plasma and erythrocytes by certain phosphate esters Fed. Proc. 1947, 6, 311 305. BROWN, H. V. & BUSH, A. F. Parathion inhibition of cholinesterase Arch. industr. Hyg. 1950, 1, 633-636 306. BURGEN, A. S. V., KEELE, C. A. & MCALPINE, D. Tetra-ethylpyrophosphate in myasthenia gravis Lancet, 1948, 1, 519 307. D1ROBERT, L. et al. Etude anatomoclinique d'une intoxication par le thiophosphate de diethyl para- nitrophenyl Ann. Mid. Ieg. 1950, 30, 32-34 308. FAUST, J. Poisoning due to tetraethylpyrophosphate J. Amer. med. Ass. 1949, 141, 192-193 10 560 PESTICIDES 309. GARLICK, W. L. Cholinesterase test aid in diagnosis of parathion poisoning Industr. Hyg. Newslett. 1950, 10, No. 9, p. 11 310. GOLDBLATT, M. W. Organic phosphorus insecticides and the antidotal action of atropine Pharm. J. 1950, 164, 229-233 311. GRANDJEAN, L. C. Forgiftning med parathion (" Bladan "); atropinsulfat som antidot Ugeskr. Laeg. 1950, 112, 86 312. GRANr, W. M. Miotic and antiglaucomatous activity of tetraethylpyrophosphate in human eyes Arch. Ophthal. (Chicago), 1948, 39, 579-586 313. GROB, D., GARLICK, W. L. & HARVEY, A. McG. The toxic effects in man of the anticholinesterase insecticide parathion (p-nitrophenyl diethyl thionophosphate Bull. Johns Hopk. Hosp. 1950, 87, 106-129 314. GROB, D. & HARVEY, A. McG. Observations on the effects of tetraethyl pyrophosphate (TEPP) in man, and on its use in the treatment of myasthenia gravis Bull. Johns. Hopk. Hosp. 1949, 84, 532-567 315. GROB, D. et al. Death due to parathion, an anticholinesterase insecticide Ann. intern. Med. 1949, 31, 899-904 316. HAGEN, J. & REINL, W. Vergiftungen durch das neuartige Schadlingsbekiimpfungsmittel E605f und verwandte Stoffe Miunch. med. Wschr. 1950, 92, 449-459 317. HAMBLIN, D. 0. & MARCHAND, J. F. Parathion poisoning Amer. Practit. (Philad.), 1951, 2, 1-12 318. HAMBLIN, D. 0. & MARCHAND, J. F. Phosphate ester poisoning, a new problem for the internist Ann. intern. Med. 1952, 36, 50-55 319. HARVEY, A. M. Some physiological experiments of nature in the field of neuro-muscular function: tetraethyl pyrophosphate in the treatment of myasthenia gravis Proc. Inst. Med. Chicago, 1948, 17, 182 320. HECHT, G. Zur Behandlung der E 605-Vergiftung Dtsch. med. Wschr. 1952, 77, 783-784 321. HEYMANS, C., VERBEKE, R. & VOTAVA, Z. Cholinesterases, sympt6mes cholinergiques et sensibilit6 i I'acetylcholine Arch. int. Pharmacodyn. 1948, 77, 486-494 322. HUMPERDINCK, K. Gewerbliche Schadigung durch E 605 ? Med. Klin. 1951, 46, 719-721 EFFECTS ON MAN - EFFETS SUR L'HOMME 561

323. JANTZEN, G. Beitrag zur Symptomatologie der E 605-Vergiftung des Menschen Dtsch. med. Wschr. 1951, 76, 1601-1602 324. KAY, K. et al. Parathion exposure and cholinesterase response of Quebec apple growers (No. 23 L (mimeographed)) [1951] 325. LAWLESS, J. J. Parathion (phosphorus compound) poisoning W. Va med. J. 1950, 46, 125 326. METCALF, R. L. The colorimetric micro-estimation of human blood cholinesterases and its application to poisoning by organic phosphate insecticides J. econ. Ent. 1951, 44, 883-890 327. MILLES, H. L. & SALT, H. B. Parathion poisoning Brit. med. J. 1950, 2, 444 328. MOUNTAIN, J. T., ZLOTOLOW, H. & O'CONOR, G. T. Determination of paranitrophenol in urine in parathion poisoning cases Industr. Hlth Mon. 1951, 11, 87-89 329. NIELSEN, 0. S. & PIPER, J. Parathionforgiftning Ugeskr. Laeg. 1950, 112, 146-148 330. NORTHERN, R. T. Parathion poisoning, its symptoms and treatment Bull. Amer. Orchid Soc. 1951, 20, 531-532 331. PARK, W. E. Parathion poisoning Minn. Med. 1950, 33, 360-362 332. Pilot reports illness from parathion dust Industr. Hyg. Newslett. 1949, 19 333. TEICHMANN, W. & HEIDSIECK, B. Zum Krankheitsbild der E-605-Vergiftung Dtsch. Gesundh Wes. 1951, 6, 1315-1317 334. TENNESSEE DEPARTMENT OF PUBLIC HEALTH AND INDUSTRIAL HYGIENE Parathion poisoning, a near fatality Tenn. industr. Hyg. News, 1949, 6, 1 335. THIODET, J., MICHAUX, P. & FOURRIER, A. Deux cas d'intoxication professionnelle par un nouvel insecticide organo-phos- phorique: le Phosph6mol 314 Algerie med. 1950, 54, 95-98; Presse med. 1950, 58, 325 336. UHRY, P. & MARCEL, G. L'intoxication par le thiophosphate de diethylparanitroph6nyl (P.A.C.) Arch. Mal. prof. 1950, 11, 589-593 337. WILHELM, G. & DOMENJOZ, R. Therapeutische Moglichkeiten bei der Parathion-Vergiftung Arch. int. Pharmacodyn. 1951, 86, 321-334 562 PESTICIDES 338. WILLIAMS, J. W. Parathion poisoning J. Fla med. Ass. 1950, 37, 293-295 339. WILLIAMS, J. W. & GRIFFITHS, J. T., JR. Parathion poisoning in citrus spray operations J. Fla med. Ass. 1951, 37, 707-709 340. WITTICH, F. W. Respiratory tract allergic effects from chemical air pollution Arch. industr. Hyg. 1950, 2, 329-334

F. Herbicides

341. BIDSTRUP, P. L. & PAYNE, D. J. H. Poisoning by dinitro-ortho-cresol. Report of eight fatal cases occurring in Great Britain Brit. med. J. 1951, 2, 16-19 342. HARVEY, D. G., BIDSTRUP, P. L. & BONNELL, J. A. L. Poisoning by dinitro-ortho-cresol Brit. med. J. 1951, 2, 13-16 343. LUIJT, P. A. VAN Quelques intoxications par le dinitro-orthocresol Arch. Mal. prof. 1947, 8, 262-264 344. MALTER, A. Intoxications survenues au cours de la fabrication d'un insecticide a base de dinitrocr6sol Arch. belges Med. soc. 1949, 7, 475-481 345. NORDMANN, M. & WEBER, 0. Tddliche Dinitroorthokresol-Vergiftung Arch. Gewerbepath. Gewerbehyg. 1938, 8, 441-448 346. POLLARD, A. B. & FILBEE, J. F. Recovery after poisoning with di-nitro-ortho-cresol Lancet, 1951, 2, 618-619 347. STEER, C. Death from di-nitro-ortho-cresol Lancet, 1951, 1, 1419

G. Fungicides G. Fongicides 348. AHLMARK, A. Poisoning by methyl mercury compounds Brit. J. industr. Med. 1948, 5, 117-119 EFFECTS ON ANIMALS - EFFETS SUR LES ANIMAUX 563

349. AHLMARK, A. & TUNBLAD, B. The toxicity of organic mercurial compounds used as seed dressings Proc. 2nd Int. Congr. PI. Prot. 1949, 1951, 2, 78-79 350. RirTER, W. L. & NUSSBAUM, M. A. Occupational illnesses in cotton industries. III. The mercury hazard in seed treating Mississippi Dr, 1945, 22, 262

H. Rodenticides 351. FRICK, E. J. & BOEBEL, F. W. Clinical observation of " 1080" poisoning Vet. Med. 1946, 41, 196-197 352. GAJDUSEK, D. C. & LUTHER, G. Fluoroacetate poisoning, review and report of a case Amer. J. Dis. Child. 1950, 79, 310-320 353. HOLMES, R. W. & LOVE, J. Suicide attempt with warfarin, a bihydroxycoumarin-like rodenticide J. Amer. med. Ass. 1952, 148, 935-937 354. KELLUM, J. M. Warfarin for suicide J. Amer. med. Ass. 1952, 148, 1443 355. KOHN-ABREST, E. et al. Intoxication aigue par ingestion de fluorure de sodium Ann. Mid. leg. 1946, 26, 134-136 356. LANDE, L. et al. Intoxication volontaire par un m6lange de fluorure de sodium et de fluosilicate de baryum Ann. Med. Mg. 1946, 26, 131-133 357. PLEYDELL, M. J. An outbreak of food poisoning in Bromyard District [due to Salmonella bovis morbificans in rat poison] Brit. med. J. 1949, 2, 264-265

V. EFFECTS ON DOMESTIC ANIMALS V. EFFETS SUR LES ANIMAUX DOMESTIQUES

358. ARNOLD, R. M. Death of calves following dipping in chlordane J. Amer. vet. med. Ass. 1949, 115, 462-463 359. BELOT, J. & BELOT, P. Du danger pour les animaux domestiques des insecticides a base d'hexachlorocyclohexane Ann. Falsif. (Paris), 1949, 42, 45-47 564 PESTICIDES 360. BISKIND, M. S. DDT poisoning and X disease in cattle J. Amer. vet. med. Ass. 1949, 114, 20 361. BUSHLAND, R. C., WELLS, R. W. & RADELEFF, R. D. Effect on livestock of sprays and dips containing new chlorinated insecticides J. econ. Ent. 1948, 41, 642-645 362. CHOUDHURY, B. & ROBINSON, V. D. Clinical and pathological effects produced in goats by the ingestion of toxic amounts of chlordan and toxaphene Amer. J. vet. Res. 1950, 11, 50-57 363. DYRENDAHL, S., HANSEN, H.-J. & LANNEK, N. Om rAittgiftet Antu och akut Antuforgiftning hos hund Skand. Vet. T. 1948, 38, 193-212 364. ENDREJAT, E. Hexachlorcyclohexan-Praparate in der Schafraudebehandlung Tierairztl. Umsch. 1950, 24 365. ENIGK, K. Die Insektizide in der Veterinar-Medizin Mh. prakt. Tierheilk. 1950, 4, 193 366. FRICK, E. J. & FORTENBERRY, J. Equine antu poisoning Vet. Med. 1948, 43, 107-108 367. GARCiA MATA, E. Acci6n del DDT sobre la salud de los bovinos Consorcio de Cent. Agr. B. 1950, 12, No. 64, pp. 13-16 368. GIBBONS, W. J., SHOFFEITT, P. E. & FOLSE, D. S. DDT and X disease J. Amer. vet. med. Ass. 1949, 115, 364-366 369. GRAU, H. & WOJTEK, H. Ober Schadenfalle bei Schafbadungen mit Hexachlorcyclohexan TierdrztL Umsch. 1950, No. 7-8, p. 119 370. HACKMAN, R. H. The persistence of DDT on cattle J. Coun. sci. industr. Res. Aust. 1947, 20, 56-65 371. HOFFBERGER, 0. DDT-Vergiftung bei einer Ziege Mh. VetMed. 1950, p. 15 372. JENSEN, R., TOBISKA, J. W. & WARD, J. C. Sodium fluoroacetate (compound 1080) poisoning in sheep Amer. J. vet. Res. 1948, 9, 370-372 373. JONES, L. M., SMITH, S. A. & SMITH, H. A. Alpha-naphthyl thiourea (ANTU) poisoning in dogs Amer. J. vet. Res. 1949, 10, 160-167 374. KING, H. C. P. DDT poisoning in a cat Vet. Rec. 1946, 58, 469 EFFECTS ON ANIMALS - EFFETS SUR LES ANIMAUX 565

375. KINGSCOTE, A. A., HENDERSON, J. A. & MCINTOSH, R. A. Observations upon the effect of spraying cattle with excessive quantities of DDT and black disinfectant Canad. J. comp. Med. 1946, 10, 322-324 376. KNIPLING, E. F. Insecticides for livestock pest control Soap (N.Y.), 1950, 26, No. 6, pp. 130-131, 133, 135, 155, 157 377. KOGER, L. M. DDT poisoning in a cow J. Amer. vet. med. Ass. 1949, 115, 22-23 378. MCENERNEY, P. J. Accidental poisoning of dairy calves by benzene hexachloride Cornell Vet. 1951, 41, 292-295 379. MARCENAC, N. Du danger des insecticides organiques de synthese pour les mammif6res domestiques C. R. Acad. Agric. Fr. 1951, 37, 171-174 380. MITCHELL, J. W., HODGSON, R. E. & GAETJENS, C. A. Tolerance of farm animals to feed containing 2,4-dichlorophenoxyacetic acid J. Anim. Sci. 1946, 5, 226-232 381. NICHOLS, M. C. et al. Report of poisoning two dogs with 1080 rat poison (sodium fluoroacetate) J. Amer. vet. med. Ass. 1949, 115, 355-356 382. PETUNIN, F. A., MANZHOS, M. D. & PONOMAREVA, N. L. Ispitanie toxitchnosti kormov opilennich doustom DDT Veterinarija, 1951, 28, No. 10, pp. 29-32 383. RADELEFF, R. D. & BUSHLAND, R. C. Acute toxicity of chlorinated insecticides applied to livestock J. econ. Ent. 1950, 43, 358-364 384. RADELEFF, R. D. et al. Effects on beef cattle of prolonged treatment with a DDT spray Vet. Med. 1952, 47, 94-96 385. SCHNAUrZ, J. 0. Sodium fluoroacetate (compound 1080) poisoning in cattle J. Amer. vet. med. Ass. 1949, 114, 435 386. SCHWARTE, L. H. The toxicity of sodium monofluoracetate (1080) for swine and chickens J. Amer. vet. med. Ass. 1947, 111, 301-303 387. TELFORD, H. S. & GUrHRIE, J. E. Toxicity of DDT sprays to livestock Soap (N.Y.), 1946, 22, No. 9, pp. 124-125, 133 388. WELCH, H. Tests of the toxicity to sheep and cattle of certain of the newer insecticides J. econ. Ent. 1948, 41, 36-39 389. WILSON, H. F. et. al. Feeding experiments with DDT-treated pea vine silage with special reference to dairy cows, sheep, and lalratory animals J. econ. Ent. 1946, 39, 801-806 566 PESTICIDES

VI. EXPERIMENTAL STUDIES VI. ETUDES EXPERIMENTALES

B. Insecticides: DDT and Related Compounds B. Insecticides: DDT et Compose's Voisins

390. ALLEN, N. N., LARDY, H. A. & WILSON, H. F. The effect of ingestion of DDT upon dairy cows J. Dairy Sci. 1946, 29, 530-531 391. BLANCO, J. L. Estudio farmacol6gico del DDT en animales de experimentacion Farmacoter. actual, 1946, 3, 595-603 392. BRAECKEL, VAN Note au sujet de la toxicite du DDT Ann. Soc. belge Med. trop. 1950, 30, 599-600 393. BRITO-BABAPULLE, L. A. P. An antidote for DDT poisoning. A record of 35 cases seen Brit. vet. J. 1951, 107, 106-122 394. BROMILEY, R. B. & BARD, P. Tremor and changes in reflex status produced by DDT in decerebrate, decerebrate- decerebellate and spinal animals Bull. Johns Hopk. Hosp. 1949, 84, 414-429 395. CALVERY, H. 0. Toxicity of DDT by oral, parenteral and cutaneous administration Proc. ent. Soc. Wash. 1945, 47, 31-32 396. CAMERON, G. R. & BURGESS, F. The toxicity of 2,2-bis(p-chlorphenyl)-1,1,1-trichlorethane (DDT) Brit. med. J. 1945, 1, 865-871 397. CAMERON, G. R. & KWOK-KEW CHENG Failure of oral DDT to induce toxic changes in rats Brit. med. J. 1951, 2, 819-821 398. CAREY, E. J. et al. Morphologic effects of DDT on nerve endings, neurosomes, and fiber types in voluntary muscles Proc. Soc. exp. Biol. (N.Y.), 1946, 62, 76-83 399. CHOU, C., KWANG, D. R. & CHU, C. H. U. On the toxicity of DDT (dichlorodiphenyltrichloroethane) in mammals Proc. Chin. physiol. Soc., Chengtu Br. 1945, 2, 164-171 400. CRESCITELLI, F. & GILMAN, A. Electrical manifestations of the cerebellum and cerebral cortex following DDT administration in cats and monkeys * Amer. J. Physiol. 1946, 147, 127-137 EXPERIMENTAL STUDIES - ETUDES EXPERIMENTALES 567

401. DERZELLE, E. Intoxication d'un chien par le DDT Ann. Med. vet. 1951, 95, 44-47 402. DIAZ-JIMINEZ, C. Contribucion al estudio de la toxicidad del DDT Med. colon. 1947, 9, 51-75 403. DOMENJOZ, R. Experimentelle Erfahrungen mit einem neuen Insektizid (Neocid-Geigy), ein Beitrag zur Theorie der Kontaktgiftwirkung Schweiz. med. Wschr. 1944, 74, 952-958 404. DRAIZE, J. H., NELSON, A. A. & CALVERY, H. 0. The percutaneous absorption of DDT (2,2,-bis(p-chlorophenyl)-1,1,1-trichloroethane) in laboratory animals J. Pharmacol. 1944, 82, 159-166 405. DRAIZE, J. H. et al. Summary of toxicological studies of the insecticide DDT-2.2-bis(p-chlorophenyl)- 1,1,1-trichlorethane Chem. Engng News, 1944, 22, 1503-1504 406. DRESDEN, D. Site of action of D.D.T and cause of death after acute D.D.T poisoning Nature (Lond.), 1948, 162, 1000-1001 407. DUNN, J. E., DUNN, R. C. & SMITH, B. S. Skin-sensitizing properties of DDT for the guinea pig Publ. Hith Rep. (Wash.), 1946, 61, 1614-1620 408. DURBIN, J. Contribution a' l'etude des intoxications par le DDT, Paris, 1951 (These) 409. EGOROV, I. A., LEONTEV, F. M. & MASHIROVA, J. P. [Sur les proprietes toxiques du DDT pour les chevaux] Veterinarija, 1948, No. 9, pp. 33-34 410. EMMEL, L. & KRUYPE, M. Beitrage zur Wirkungsweise des 4,4'-Dichlor-diphenyl-trichlormethylmethans beim Warmbluter Z. Naturf. 1946, 1, 691-695 411. EYZAGUIRRE, C. & LILIENTHAL, J. L. Veratrinic effects of pentamethylene-tetrazol (Metrazol) and 2,2,-bis(p-chlorophenyl)-l,1,1-trichloroethane (DDT) on mammalian neuromuscular function Proc. Soc. exp. Biol. (N.Y.), 1949, 70, 272-275 412. FINNEGAN, J. K., HAAG, H. B. & LARSON, P. S. Tissue distribution and elimination of DDD and DDT following oral administration to dogs and rats Proc. Soc. exp. Biol. (N.Y.), 1949, 72, 357-360 413. FITZHUGH, 0. G. & NELSON, A. A. The chronic oral toxicity of DDT J. Pharmacol. 1947, 89, 18-30 414. GEREBTZOFF, M. A., DALLEMAGNE, M. J. & PHILIPPOT, E. Plasmocytomes renaux multiples et plasmocytose i la suite d'injections r6p6t6es de DDT au chien C. R. Soc. Biol. (Paris), 1950, 144, 1135-1137 568 PESTICIDES

415. GLASSMAN, J. M. & BUCHAN, R. F. 2,2-bis(p-chlorophenyl)-1,1,1-trichloroethane (DDT). A review of mammalian toxicity studies Occup. Med. 1948, 5, 536-560 416. GLOBUS, J. H. DDT poisoning. Histopathological observations on the central nervous system in so-treated monkeys, dogs, cats, and rats Trans. Amer. neurol. Ass. 1948, 73, 202-208 417. GLOBUS, J. H. DDT (2,2-bis(p-chlorophenyl)-1,1,1-trichlorethane) poisoning; histopathologic observations on central nervous system in so-treated monkeys, dogs, cats and rats J.,Neuropath. 1948, 7, 418-431 418. GUARESCHI, G. & BINI, G. Ricerche sperimentali sulla tossicita del DDT con particolare riguardo all'emuntorio renale Ateneo parmense, 1948, 19, 72-81 419. HAAG, H. B. Insecticide storage in adipose tissue (DDD) J. Amer. med. Ass. 1951, 147, 1381 420. HAAG, H. B. et al. Comparative chronic toxicity for warm-blooded animals of 2,2-bis(p-chlorophenyl)-1,1,1-trichloro-ethane (DDT) and 2,2-bis(p-chlorophenyl)-1,1-dichloroethane (DDD) Industr. Med. Surg. 1948, 17, 477-484 421. HAAG, H. B. et al. Comparative chronic toxicity for warm-blooded animals of 2,2-bis(p-chlorophenyl)-1,1,1, trichloro-ethane (DDT) and 2,2-bis-(p-methoxyphenyl)-1,1,1-trichloroethane (DMDT, methoxychlor) Arch. int. Pharmacodyn. 1950, 83, 491-504 422. HARRIS, J. R. et al. Concentration of DDT in the blood and tissues of sheep fed varying levels of DDT Arch. Biochem. 1949, 21, 370-376 423. HARRIS, L. E. et al. Effect of feeding DDT dusted alfalfa hay to fattening lambs J. Anim. Sci. 1951, 10, 581-591 424. HAYMAKER, W., GINZLER, A. M. & FERGUSON, R. L. The toxic effects of prolonged ingestion of DDT on dogs with special reference to lesions in the brain Amer. J. med. Sci. 1946, 212, 423-431 425. HODGE, H. C. et al. Short-term oral toxicity tests of methoxychlor (2,2 di-(p-methoxy phenyl)-1,1,1- trichlorethane) in rats and dogs J. Pharmacol. 1950, 99, 140148 426. JANDORF, B. J., SAREIT, H. P. & BODANSKY, 0. Effect of oral administration of DDT on the metabolism of glucose and pyruvic acid in rat tissues J. Pharmacol. 1946, 88, 333-337 EXPERIMENTAL STUDIES - ETUDES EXPERIMENTALES 569

427. JOHNSTON, C. D. The in vitro effect of DDT and related compounds on the succinoxidase system of rat heart Arch. Biochem. 1951, 31, 375-382 428. JONES, L. M. Some aspects of the pharmacology of DDT N. Amer. Vet. 1946, 27, 492-494 429. JUDAH, J. D. Studies on the metabolism and mode of action of DDT Brit. J. Pharmacol. 1949, 4, 120-131 430. KINGSCOTE, A. A. Further observations upon the tolerance of cattle to DDT Canad. J. comp. Med. 1946, 10, 348-349 431. KONST, H. & PLUMMER, P. J. G. Studies on the toxicity of DDT for domestic and laboratory animals Canad. J. comp. Med. 1946, 10, 128-136 432. KOSTER, R. Differentiation of gluconate, glucose, calcium and insulin effects on DDT poisoning in cats Fed. Proc. 1947, 6, 346 433. KUNZE, F. M., LAUG, E. P. & PRICKETT, C. S. Storage of methoxychlor in the fat of the rat Fed. Proc. 1950, 9, 293 434. KUNZE, F. et al. Storage of DDT in the fat of the rat Fed. Proc. 1949, 8, 311 435. LXUGER, P., PULVER, R. & MONTIGEL, C. Ober die Wirkungsweise von 4,4'-dichlordiphenyltrichlormethylmethan (DDT- Geigy) im Warmbluterorganismus Helv. physiol. pharmacol. Acta, 1945, 3, 405-411 436. LAUG, E. P. 2,2-bis(p-chlorophenyl)-1,1,1-trichloroethane (DDT) in the tissues, body fluids and excreta of the rabbit following oral administration J. Pharmacol. 1946, 88, 332-335 437. LAUG, E. P. & FITZHUGH, 0. G. 2,2-bis(p-chlorophenyl)-1,1,l-trichloroethane (DDT) in the tissues of the rat following oral injection for periods of six months to two years J. Pharmacol. 1946, 87, 18-23 438. LAUG, E. P. et al. Liver cell alteration and DDT storage in the fat of the rat induced by dietary levels of 1 to 50 p.p.m. DDT J. Pharmacol. 1950, 98, 268-273 439. LEWIS, W. H. & RICHARDS, A. G. JR. Non-toxicity of DDT on cells in cultures Science, 1945, 102, 330-331 440. LILLIE, R. D. & SMITH, M. I. Pathology of experimental poisoning in cats, rabbits, and rats with 2,2 bis-para- chlorphenyl-1,,1-trichloroethane Publ. Hlth Rep. (Wash.), 1944, 59, 979-984 570 PESTICIDES

441. LILLIE, R. D., SMITH, M. I. & STOHLMAN, E. F. Pathologic action of DDT and certain of its analogs and derivatives Arch. Path. 1947, 43, 127-142 442. LUDEWIG, S. & CHANUTIN, A. Distribution of 2,2 (p-chlorophenyl)-1,1,l-trichlorethane (DDT) in tissues of rats after its ingestion Proc. Soc. exp. Biol. (N.Y.), 1946, 62, 20-21 443. MCNAMARA, B. P., BING, R. J. & HOPKINS, F. Studies of chronic toxicity of DDT in the dog Fed. Proc. 1946, 5, 67-68 444. MARCO, S. [Experimental DDT lesions] Boll. Soc. ital. Biol. sper. 1949, 25, 1316-1317 445. NEAL, P. A. A report on the toxicity to warm-blooded animals of aerosols, mists, and dusting powders containing DDT Soap (N.Y.), 1945, 21, 1, No. 99-101, pp. 111 446. NEAL, P. A. & OETTINGEN, W. F. VON Toxicity of DDT: a report on experimental studies Soap (N.Y.), 1946, 22, No. 7, pp. 135-143 447. NEAL, P. A. et al. Toxicity and potential dangers of aerosols, mists, and dusting powders containing DDT, Washington, D.C., 1944 (Supplement No. 177 to the Public Health Reports) 448. NEAL, P. A. et al. Toxicity andpotential dangers ofaerosols and residues from such aerosols containing three percent DDT (second report), Washington, D.C., 1945 (Supplement No. 183 to the Public Health Reports) 449. NELSON, A. A. & WOODARD G., Adrenal cortical atrophy and liver damage produced in dogs by feeding 2,2-bis- (parachlorophenyl)-l1,l-dicloroethane (DDD) Fed. Proc. 1948, 7, 276-277 450. NELSON, A. A. & WOODARD, G. Severe adrenal cortical atrophy (cytotoxic) and hepatic damage produced in dogs by feeding 2,2-bis(parachlorophenyl)-1,1-dichlorethane (DDD or TDE) Arch. Path. 1949, 48, 387-394 451. NELSON, A. A. et al. Histopathological changes following administration of DDT to several species of animals Publ. Hlth Rep. (Wash.), 1944, 59, 1009-1020 452. NEVE, H. Toxic effects of DDT on a cat Vet. Med. 1947, 42, 78; Vet. Rec. 1946, 58, 43 453. NICHOLS, J. & GARDNER, L. I. Production of insulin sensitivity with the adrenocorticolytic drug DDD J. Lab. clin. Med. 1951, 37, 229-238 EXPERIMENTAL STUDIES - ETUDES EXPrRIMENTALES 571

454.7OFNER, R. R., WOODARD, G. & CALVERY, H. 0. Studies of the metabolism of 2,2-bis-(parachlorophenyl)l,1,1-trichloroethane (DDT) Fed. Proc. 1945, 4, 132 455. ORR, L. W. & MoTT, L. 0. The effects of DDT administered orally to cows, horses and sheep J. econ. Ent. 1945, 38, 428-432 456. PHILIPS, F. S. & GILMAN, A. Studies on the pharmacology of DDT. I. The acute toxicity of DDT following intravenous injection in mammals with observations on the treatment of acute DDT poisoning J. Pharmacol. 1946, 86, 213-221 457. PHILIPS, F. S., GILMAN, A. & CRESCITELLI, F. Studies on the pharmacology ofDDT (2,2-bis(p-chlorophenyl) 1,1I,1-trichloroethane. II. The sensitization of the myocardium to sympathetic stimulation during acute DDT intoxication J. Pharmacol. 1946, 86, 222-228 458. PHILIPS, F. S., GILMAN, A. & CRESCITELLI, F. The sensitization of the myocardium to sympathetic stimulation during acute DDT intoxication in animals Fed. Proc. 1946, 5, 80 459. PIEKARSKI, F. & HOLZ, K. [Action of the commercial contact insecticide " Gix" on rats and mice] Arch. exp. Path. Pharmak. 1950, 210, 71-90 460. PLUVINAGE, R. J. & HEATH, J. W. Neural effects of DDT poisoning in cats Proc. Soc. exp. Biol. (N.Y.), 1946, 63, 212-214 461. POTOSSI, 0. Quadri anatomo-istopatologici nell'intossicazione sperimentale da DDT Boll. Soc. ital. Biol. sper. 1947, 23, 1084-1087 462. RIKER, W. F., JR. et al. Studies on DDT (2,2-bis-parachloro phenyl-l,l,l, trichlorethane): effects on oxida- tive metabolism J. Pharmacol. 1946, 88, 327-332 463. SALVA MIQUEL, J. A. Absorcion y toxicidad percutAnea del DDT en animales de sangre caliente Act. dermo-sifiliogr. (Madr.), 1947, 38, 606-612 464. SARETT, H. P. & JANDORF, B. J. Effects of chronic intoxication of rats with DDT on lipids and other constituents of the liver Fed. Proc. 1946, 5, 151-152; J. Pharmacol. 1947, 91, 340-344 465. SAUBERLICH, H. E. & BAUMANN, C. A. Effect of dietary variations upon the toxicity of DDT to rats or mice Proc. Soc. exp. Biol. (N.Y.), 1947, 66, 642-645 466. SERGENT, Ed. & SERGENT, Et. Toxicite du DDT pour les souris et les rats C. R. Acad. Sci. (Paris), 1948, 227, 416-419 572 PESTICIDES

467. SMITH, M. I., JUNGE, J. M. & MACCLOSKY, W. T. The pharmacologic and chemotherapeutic action of p,p'-diaminodiphenyltri- chloroethane J. Amer. pharm. Ass. 1948, 37, 461464 468. SMITH, M. I. & STOHLMAN, E. F. The pharmacologic action of 2,2 bis(p-chlorophenyl)-1,1,1-trichlorethane and its estimation in the tissues and body fluids Publ. Hlth Rep. (Wash.), 1944, 59, 984-993 469. SMITH, M. I. & STOHLMAN, E. F. Further studies on the pharmacologic action of 2,2 bis(p-chiorophenyl)-1,j,1 trichlorethane (DDT) Publ. Hlth Rep. (Wash.), 1945, 60, 289-301 470. SMITH, M. I. et al. The pharmacologic action and metabolism of a series of compounds chemically related to DDT Fed. Proc. 1946, 5, 203-204 471. SMITH, M. I. et al. The pharmacologic action of certain analogues and derivatives of DDT J. Pharmacol. 1946, 88, 359-365 472. SPENCER, H. C., ROWE, V. K., ADAMS, E. M. & IRISH, D. D. Toxicologic studies on the new miticide bis(parachlorophenoxy)-methane; acute and semichronic toxicity Arch. industr. Hyg. 1950, 1, 341-347 473. SPICER, S. S. et al. Toxicological observations on goats fed large doses of DDT Vet. Med. 1947, 42, 289-293 474. STASSI, M. Lesioni sperimentali da DDT Boll. Soc. ital. Biol. sper. 1949, 25, 1316-1317 475. STIFF, H. A. JR. & CASTILLO, J. C. Determination of DDT in organs and body fluids after oral administration J. biol. Chem. 1945, 159, 545-548 476. STOHLMAN, E. F. Preliminary report on the identification of 2,2 bis(p-chlorophenyl)-l,1,1 trichlorethane (DDT) in the excreta of poisoned rabbits Publ. Hlth Rep. (Wash.), 1945, 60, 350-353 477. STOHLMAN, E. F. & LILLIE, R. D. The effect of DDT on the blood sugar and of glucose administration on the acute and chronic poisoning of DDT in rabbits J. Pharmacol. 1948, 43, 351-361 478. STOHLMAN, E. F. & SMITH, M. I. The isolation of di(p-chlorophenyl)-acetic acid (DDA) from the urine of rabbits poisoned with 2,2 bis(p-chlorophenyl)-l,1,l-trichlorethane (DDT) J. Pharmacol. 1945, 84, 375-379 479. TARSITANO, F. Ricerche sull'avv-lenamento da DDT Folia med. (Napoli), 1948, 31, 297-306 EXPERIMENTAL STUDIES - ETUDES EXPIRIMENTALES 573

480. THOMAS, J. W. et al. Feeding DDT and alfalfa sprayed with DDT to calves J. Dairy Sci. 1951, 34, 203-208 481. TRUHAUT, R. & VINCENT, D. Contribution 'a l'etude du mecanisme de l'action toxique de l'insecticide DDT Bull. Soc. Chim. biol. (Paris), 1948, 30, 694-699 482. TRUHAUT, R. & VINCENT, D. Sur le mecanisme d'action toxique du DDT. DDT et cholinest6rase du s6rum Ann. pharm. fran9. 1947, 5, 159-163 483. VAZ, Z., PEREIRA, R. S. & MALHEIRO, D. M. Calcium in prevention and treatment of experimental DDT poisoning Science, 1945, 101, 434-436 484. VINCENT, D. & TRUHAUT, R. Contribution a l'etude du mecanisme de l'action physiologique de l'insecticide DDT. DDT et cholinesterase du serum C. R. Soc. Biol. (Paris), 1947, 141, 65-66 485. VINCENT, D, TRUHAUT, R. & ABADIE, A. Contribution 'a l'etude du mecanisme de l'action toxique de l'insecticide DDT. DDT et systemes cholinesterasiques chez les animaux superieurs et les insectes C. R. Soc. Biol. (Paris), 1948, 142, 1500-1502 486. VIRGILI, R. & MARCHIAFAVA, G. Quadri anatomo-patologici nell'intossicazione acuta sperimentale da DDT con particolare riferimento al sistema nervoso Riv. Malariol. 1949, 28, 107-124 487. VON OETTINGEN, W. F. & SHARPLESS, N. E. The toxicity and toxic manifestations of 2,2-bis-(p-chlorophenyl)-1,1,1-trichloroethane (DDT) as influenced by chemical changes in the molecule J. Pharmacol. 1946, 88, 400-413 488. WELSH, J. H. & GORDON, H. T. The mode of action of DDT Fed. Proc. 1946, 5, 112 489. WHITE, W. C. & SWEENEY, T. R. The metabolism of 2,2 bis(p-chlorophenyl)-1,1,1 trichlorethane (DDT). I. Publ. Hlth Rep. (Wash.), 1945, 60, 66-71 490. WOODARD, G., DAVIDOW, B. & NELSON, A. A. Effects observed in dogs following the prolonged feeding of DDT and its analogues Fed. Proc. 1948, 7, 266-267 491. WOODARD, G., NELSON, A. A. & CALVERY, H. 0. Acute and subacute toxicity of DDT (2,2,-bis(p-chlorophenyl)-1,1,1-trichloroethane) to laboratory animals J. Pharmacol. 1944, 82, 152-158 492. WOODARD, G. & OFNER, R. R. Accumulation of DDT in the fat of rats in relation to dietary level and length of feeding Fed. Proc. 1946, 5, 215 493. WOODARD, G., OFNER, R. R. & MONTGOMERY, C. M. Accumulation of DDT in the body fat and its appearance in the milk of dogs Science, 1945, 102, 177-178 574 PESTICIDES

C. Insecticides: Aldrin, Chlordane, Dieldrin, and Toxaphene C. Insecticides: Aldrine, Chlordane, Dieldrine, et Toxaphene

494. BUNDREN, J., HOWELL, D. E. & HELLER, V. G. Absorption and toxicity of dieldrin Proc. Soc. exp. Biol. (N.Y.), 1952, 79, 236-238 495. CHOUDHURY, B. & ROBINSON, V. D. Clinical and pathological effects produced in goats by the ingestion of toxic amounts of chlordan and toxaphene Amer. J. vet. Res. 1950, 11, 50-57 496. FRINGS, H. & O'TOUSA, J. E. Toxicity to mice of chlordane vapour and solutions administered cutaneously Science, 1950, 111, 658-660 497. HAYES, W., JR., FERGUSON, F. F. & CASS, J. S. The toxicology of dieldrin and its bearing on field use of the compound Amer. J. trop. Med. 1951, 31, 519-522 498. INGLE, L. Toxicity of chlordane to white rats J. econ. Ent. 1947, 40, 264-268 499. KITSELMAN, C. H., DAHM, P. A. & BORGMANN, A. R. Toxicological studies of aldrin (compound 118) on large animals Amer. J. vet. Res. 1950, 11, 378-381 500. LACKEY, R. W. Observations on the acute and chronic toxicity of toxaphene in the dog J. industr. Hyg. 1949, 31, 117-120 501. LACKEY, R. W. Observations on the percutaneous absorption of toxaphene in the rabbit and the dog. II. J. industr. Hyg. 1949, 31, 155-157 502. LACKEY, R. W. & WEED, 0. Treatment of acute toxaphene poisoning in the dog Sth med. J. (Bgham, Ala), 1951, 44, 165-166 503. RADELEFF, R. D. Toxaphene poisoning: symptomatology and pathology Vet. Med. 1949, 44, 436-442 504. STOHLMAN, E. F. & SMITH, M. I. Toxicological action and metabolic fate of chlordan In: American Chemical Society, Division of Agricultural and Food Chemistry, Agricultural control chemicals, Washington, D.C., 1950, pp. 228-231 505. STOHLMAN, E. F., THORP, W. T. S. & SMITH, M. I. Pharmacologic action of chlordane Fed. Proc. 1949, 8, 334 506. STOHLMAN, E. F., THORP, W. T. S. & SMITH, M. I. Toxic action of chlordan Arch. industr. Hyg. 1950, 1, 13-19 EXPERIMENTAL STUDIES - ETUDES EXPERIMENTALES 575

D. Insecticides: Gamma-Isomer Benzene Hexachloride and its Isomers D. Insecticides: Hexachlorocyclohexane. Isomere Gamma et Autres Isomeres

507. BARKE, A. Zur Toxizitat des Kontaktinsektizids Hexachlorcyclohexan Mh. prakt. Tierheilk. 1949, 1, 213-221 508. BARKE, A. Zur Toxizitat der Gamma-Isomere des Hexachlorcyklohexans Tierdrztl. Umsch. 1950, 5, 61-63 509. BLOOD, D. C., CRAVEN, C. P. & ASTILL, K. J. The toxicity of gammexane for cats Aust. vet. J. 1948, 24, 13 510. Buu HOI, N. P. et al. Identite d'action sur les mammiferes de trois d6riv%s du cyclohexane apparentes au meso-inositol C. R. Soc. Bibl. (Paris), 1950, 144, 1568-1569 511. COLLET, P. & THEOLEYRE, P. Essais sur la toxicite de 1'hexachlorocyclohexane chez les carnivores domestiques Bull. Soc. Sci. vet. Lyon, 1947, 49, 128-133 512. COPER, H., HERKEN, H. & KLEMPAU, I. Antagonismus und Synergismus des ,B- und y-Hexachlorcyclohexans Klin. Wschr. 1951, 29, 264-265 513. COPER, H., HERKEN, H. & KLEMPAU, J. Zur Pharmakologie und Toxikologie chlorierter Cyclohexane Arch. exp. Path. Pharmak. 1951, 212, 463-471 514. COPER, H. et al. Hirnelektrische Untersuchungen nach Einwirkung der krampfhindernden Hexa- chlorcyclohexane Klin. Wschr. 1952, 30, 551-553 515. CORREA, 0. [Treatment of equine gasterophilosis by gammexane and its toxicity to the horse] Rev. Agron. 1950, 14, 72 516. DALLEMAGNE, M. J. & GEREBTZOFF, M. A. Considerations sur les troubles provoques chez le mammifere, par des derives de l'hexane apparentes a l'inositol J. Physiol. (Paris), 1950, 42, 579-581 517. DALLEMAGNE, M. J., GEREBTZOFF, M. A. & PHILIPPoT, E. Fat deposits in the kidney in chronic intoxication of the dog by hexachlorocyclohexane Science, 1950, 112, 148 518. DALLEMAGNE, M. J., GEREBTZOFF, M. A. & PHILIPPOT, E. Surcharge lipidique de l'organisme dans l'intoxication chronique du chien par le y-hexachlorocyclohexane Experientia (Basel), 1950, 6, 274 * ~~~~~~~~~~~~~~~~~~~~~~~~~~~~11 576 PESTICIDES

519. DALLEMAGNE, M. J., GEREBTZOFF, M. A. & PHILIPPOT, E. Surchage lipidique du foie et des voies biliaires dans l'intoxication chronique du chien par le y-hexachlorocyclohexane C. R. Soc. Biol. (Paris), 1950, 144, 457 520. DALLEMAGNE, M. J. & PHILIPPOT, E. La toxicite de l'hexachlorocyclohexane pour les insectes et les animaux superieurs Rev. med. Liege, 1948, 3, 714-718 521. DALLEMAGNE, M. J. & PHILIPPOT, E. Recherches sur la toxicite de l'hexachlorocyclohexane Arch. int. Pharmacodyn. 1948, 76, 274-296 522. DALLEMAGNE, M. J., PHILIPPOT, E. & GERNAY, J. M. Recherches sur le mecanisme de l'action centrale de l'hexachlorocyclohexane et de la dibenzylmethylamine chez les animaux superieurs Experientia (Basel), 1948, 4, 155 523. DAVIDOW, B. & FRAWLEY, J. P. Tissue distribution, accumulation and elimination of the isomers of benzene hexachloride Proc. Soc. exp. Biol. (N.Y.), 1951, 76, 780-783 524. Doisy, E. A., JR. & BOCKLAGE, B. C. Chronic toxicity of gamma isomer of hexachlorocyclohexane in the albino rat Proc. Soc. exp. Biol. (N.Y.), 1949, 71, 490-493 525. ENZIE, F. D. & FOSTEK, A. 0. The use of calcium gluconate in the treatment of lindane poisoning of dogs Vet. Med. 1951, 46, 439-442, 450 526. FITZHUGH, 0. G., NELSON, A. A. & FRAWLEY, J. P. The chronic toxicity of technical benzene hexachloride and its alpha, beta and gamma isomers J. Pharmacol. 1950, 100, 59-66 527. FITZHUGH, 0. G., NELSON, A. A. & HOLLAND, 0. L. Comparison of the chronic toxicity of alpha, beta and gamma isomers of benzene hexachloride Fed. Proc. 1949, 8, 291-292 528. FORTUSHNIJ, V. A. & GLADENKO, I. N. [Recherches sur la toxicit6 de l'hexachlorocyclohexane sur des hom6othermes] Veterinarija, 1951, 28, 33-38 529. FURMAN, D. P. Toxicity of benzene hexachloride to mammals J. econ. Ent. 1947, 40, 518-521 530. GEREBTZOFF, M. A. & DALLEMAGNE, M. J. A propos d'un facteur influengant la toxicite chronique de l'isom6re gamma de l'hexachlorocyclohexane chez le rat C. R. Soc. Biol. (Paris), 1950, 144, 1002-1004 531. GEREBTZOFF, M. A. & DALLEMAGNE, M. J. La rupture des cenapses lipo-protidiques dans l'intoxication experimentale des mammiferes par l'hexachlorocyclohexane C. R. Soc. Bio!. (Paris), 1950, 144, 1570-1571 EXPERIMENTAL STUDIES - ETUDES EXPE'RIMENTALES 577

532. GEREBTZOFF, M. A., DALLEMAGNE, M. J. & PHILIPPOT, E. Degenerescence graisseuse des tissus musculaires dans l'intoxication chronique du chien par le y-hexachlorocyclohexane C. R. Soc. Biol. (Paris), 1950, 144, 460-461 533. GEREBTZOFF, M. A., DALLEMAGNE, M. J. & PHILIPPoT, E. Histochemical study of fat deposits in chronic intoxication of dog by y-hexachlorocyclohexane Nature (Lond.), 1950, 165, 572-573 534. GOVAERTS, J. DALLEMAGNE, M. J. & GEREBTZOFF, M. A. Influence de l'isomere gamma de l'hexachlorocyclohexane sur les phospholipides du foie, etudiee a I'aide du phosphore radioactif Bull. Soc. Chim. bio. (Paris), 1951, 33, 1277-1281 535. HERKEN, H. Anderung von Zellfunktionen im Nervensystem durch Hexachlorcyklohexan (Untersuchungen am Warmbluter) Arch. exp. Path. Pharmak. 1950, 211, 143-152 536. HERKEN, H. Bemerkungen zur Toxikologie des Hexachlorcyclohexans Pharmazie, 1950, 5, 88-89 537. HERKEN, H. Funktionsstorungen im Nervensystem nach Einwirkung von Hexachlorcyclohexan Arztl. Wschr. 1950, 5, 193-195 538. HERKEN, H. Zur Wirkung von Hexachlorcyclohexan auf das Zentralnervensystem (Warmbliter) Klin. Wschr. 1950, 28, 582-584 539. HERKEN, H. & KLEMPAU, I. Zur neurotropen Wirkung einiger Hexachlorcyklohexane Naturwissenschaften, 1950, 37, 493494 540. HOLL, W. Ober die Vertraglichkeit von Hexachlorcyclohexan beim Rind bei innerlicher Verabreichung Tierdrztl. Umsch. 1950, 5, 417-418 541. JOLLY, D. W. The toxicity of DDT and BHC for domestic animals Vet. Rec. 1952, 64, 76-81 542. JOLLY, D. W. & KANE, G. J. Toxicity of benzene hexachloride Vet. Rec. 1950, 62, 377-379 543. LAUG, E. P. Tissue distribution of a toxicant following oral infection of the gamma isomer of benzene hexachloride by rats J. Pharmacol. 1948, 93, 277-281 544. LENDLE, L. & SCHNEIDER, H.-H. Toxizitiat verschiedener Fraktionen von Hexachlorcyclohexan (HCC) bei ver- schiedenen Tierarten Pharmazie, 1950, 5, 382-384 578 PESTICIDES

545. LErARD, H. & Sacy, G. S. DE Etude toxicologique du benzene hexachlore C. R. Soc. Biol. (Paris), 1945, 139, 353-354 546. MCNAMARA, B. P. & KROP, S. Observations on the pharmacology of the isomers of hexachlorocyclohexane J. Pharmacol. 1948, 92, 140-147 547. MCNAMARA, B. & KROP, S. The treatment of acute poisoning produced by gamma hexachlorocyclohexane J. Pharmacol. 1948, 92, 147-152 548. MCNAMARA, B. P. & KROP, S. The influence of delta and gamma benzene hexachloride upon the oxygen uptake of brain Science, 1949, 109, 330-331 549. PHILIPPOT, E. & DALLEMAGNE, M. J. Nouvelles recherches relatives aux variations de la kaliemie pendant les convulsions dues it l'isomere y de l'hexachlorocyclohexane Arch. int. Pharmacodyn. 1948, 77, 82-84 550. RADELEFF, R. D. Effects of various levels of lindane in the feed of beef cattle Vet. Med. 1951, 46 (No. 3, March) 551. RODRIGUEZ GARCIA, J. A. & PERDOMO, R. S. [Pharmacological action of hexachlorocyclohexane in higher animals. Action on the central nervous system] Arch. &c. Biol. Montevideo, 1947, 14, 4245 552. TAYLOR, H. & FRODSHMAN, J. Assay of toxic effect of Gammexane on man and animals Nature (Lond.), 1946, 158, 538 553. WILSON, S. G. The feeding of " Gammexane" and DDT to bovines Bull. ent. Res. 1948, 39, 423-434 554. WITT, P. N. Ein Test zur Prufung der Wirksamkeit insektizider Substanzen und ein Beitrag zum Mechanismus der Wirkung von DDT und HCC Z. Naturf. 1947, 2b, 361-366 555. WOJTEK, H. Untersuchungen uber die bakterizide Wirkung eines Hexachlorcyclohexan-Pra- parates Zbl. Bakt., L Abt. Orig. 1950, 156, 270-281 556. WOODARD, G. & HAGAN, E. C. Toxicological studies on the isomers and mixtures of isomers of benzene hexachloride Fed. Proc. 1947, 6, 386 EXPERIMENTAL STUDIES - ETUDES EXPERIMENTALES 579

E. Insecticides: Organo-Phosphorus Compounds E. Insecticides Composes Phosphores Organiques

557. ALDRIDGE, W. V. Some properties of specific cholinesterase with particular reference to the mechanism of inhibition of diethyl p-nitrophenyl thiophosphate (E605) and analogues Biochem. J. 1950, 46, 451-460 558. BAIN, J. A. Mechanism of the inhibition of rat brain cholinesterase by diisopropylfluorophos- phate, tetraethylpyrophosphate, and eserine Proc. Soc. exp. Biol. (N.Y.), 1949, 72, 9-13 559. BARNES, J. M. & DENZ, F. A. The chronic toxicity of p-nitrophenyl diethyl thiophosphate (E.605); a long-term feeding experiment with rats J. Hyg. (Lond.), 1951, 49, 430-441 560. BURGEN, A. S. V. The mechanism of action of anticholinesterase drugs Brit. J. Pharmacol. 1949, 4, 219-228 561. BURGEN, A. S. V. & HOBBIGER, F. The inhibition of cholinesterases by alkylphosphates and alkylphenolphosphates Brit. J. Pharmacol. 1951, 6, 593-605 562. BURGEN, A. S. V., KEELE, C. A. & SLOME, D. Pharmacological actions of tetraethylpyrophosphate and hexaethyltetraphosphate J. Pharmacol. 1949, 96, 396-409 563. BURGEN, A. S. V. et al. Physiological effects of alkyl polyphosphates Nature (Lond.), 1947, 160, 760-761 564. CHENNELS, M., FLOYD, W. F. & WRIGHT, S. Action of condensed alkyl phosphates on the nerve-muscle preparation and the central nervous system of the cat J. Physiol. (Lond.), 1949, 108, 375-397 565. COON, J. M. & SALERNO, P. R. A pharmacologic comparison of hexaethyl tetraphosphate (HETP) and tetraethyl pyrophosphate (TEPP) with physostigmine and neostigmine Fed. Proc. 1948, 7, 212-213 566. DAHM, P. A., FOUNTAINE, F. C. & PANKASKIE, J. E. The experimental feeding of parathion to dairy cows Science, 1950, 112, 254-255 567. DAHM, P. A. et al. The effects of feeding parathion to dairy cows J. Dairy Sci. 1950, 33, 747-757 568. DAYRIT, C., MANRY, C. H. & SEEVERS, M. H. On the pharmacology of hexaethyl tetraphosphate J. Pharmacol. 1948, 92, 173-186 580 PESTICIDES

569. DEICHMANN, W. B., PUGLIESE, W. & CASSIDY, J. Effects of dimethyl and diethyl paranitrophenylthiophosphate on experimental animals Arch. industr. Hyg. 1952, 5, 44-51 570. DEICHMANN, W. B. & WITHERUP, S. The immediate toxicity of hexaethyltetraphosphate, tetraethylpyrophosphate and hexaoctyltetraphosphate to rabbits and rats Fed. Proc. 1947, 6, 322 571. DENZ, F. A. Poisoning by p-nitrophenyl diethyl thiophosphate (E.605); a contribution to the study of anticholinesterase compounds J. Path. Bact. 1951, 63, 81-91 572. DIGGLE, W. M. & GAGE, J. C. Cholinesterase inhibition by parathion Biochem. J. 1951, 48, xxv 573. DIGGLE, W. M. & GAGE, J. C. Cholinesterase inhibition by parathion in vivo Nature (Lond.), 1951, 168, 998 574. DORWARD, K. Parathion toxicity to livestock; preliminary test Florida Ent. 1948, 31, 116-122 575. DuBois, K. P. et al. Studies on the toxicity and mechanism of action of p-nitrophenyl diethyl thionophosphate (parathion) J. Pharmacol. 1949, 95, 79-91 576. DuBois, K. P. & DOULL, J. Cholinergic action of alkyl pyrophosphoramides Fed. Proc. 1950, 9, 268-269 577. DuBois, K. P., DOULL, J. & COON, J. M. Toxicity and mechanism of action of p-nitrophenyl-diethyl-thionophosphate (E 605) Fed. Proc. 1948, 7, 216 578. DuBois, K. P., DOULL, J. & COON, J. M. The cholinergic action of octamethyl pyrophosphoramide (OMPA) J. Pharmacol. 1950, 98, 6-7 579. DuBois, K. P., DOULL, J. & COON, J. M. Studies on the toxicity and pharmacological action of octamethyl pyrophosphoramide (OMPA; Pestox I1I) J. Pharmacol. 1950, 99, 376-393 580. DuBois, K. P. & MANGUN, G. H. Effect of hexaethyl tetraphosphate on choline esterase in vitro and in vivo Proc. Soc. exp. Biol. (N.Y.), 1947, 64, 137-139 581. DuBois, K. P., MAZUR, M. & COCHRAN, K. W. Toxicity and anticholinesterase action of p-nitrophenyl dimethyl thionophosphate Fed. Proc. 1950, 9, 269 582. ENDERS, A. Die Kreislaufwirkung des Parathions Arch. int. Pharmacodyn. 1952, 89, 169-174 EXPERIMENTAL STUDIES - ETUDES EXPERIMENTALES 581

583. ENDERS, A. & GRUPP, G. Die Blutveranderungen bei chronischer Vergiftung mit dem Schiidlingsbekamp- fungsmittel Parathion Arzneimittel-Forsch. 1951, 1, 79-80 584. ENGBAEK, L. & JENSEN, 0. S. Toxic and cholinesterase inhibitory action of diethyl-p-nitrophenyl thiophosphate (Parathion) Acta pharmacol. (Kbh.), 1951, 7, 189-200 585. FORSSLING, S. Contributions to the toxicology and pharmacology of hexa-ethyltetraphosphate (HTP) Acta pharmacol. (Kbh.), 1948, 4, 143-154 586. FRAWLEY, J. P., HAGAN, E. C. & FITZHUGH, 0. G. A comparative pharmacological and toxicological study of organic phosphate- anticholinesterase compounds J. Pharmacol. 1952, 105, 156-165 587. GARDOCKI, J. F. & HAZLETON, L. W. Urinary excretion of the metabolic products of parathion following its intravenous injection J. Amer. pharm. Ass. 1951, 40, 491-494 588. HAGAN, E. C. & WOODARD, G. Toxicity of o,o-diethyl o-p-nitrophenyl thiophosphate (parathion) Fed. Proc. 1948, 7, 224-225 589. HAZLETON, L. W. & GODFREY, E. Pharmacological actions of o-o-diethyl o-p, nitrophenyl thiophosphate Fed. Proc. 1948, 7, 226 590. HAZLETON, L. W. & HOLLAND, E. G. Pharmacology and toxicology of parathion In: American Chemical Society, Division of Agricultural and Food Chemistry, Agricultural control chemicals, Washington, D.C., 1950, pp. 31-38 591. HECHT, G. & WIRTH, W. Zur Pharmakologie der Phosphorsaureester. Derivate der Thiophosphorsaure Arch. exp. Path. Pharmak. 1950, 211, 264-277 592. HOBBIGER, F. The action of carbamic esters and tetraethylpyrophosphate on normal and curarized frog rectus muscle Brit. J. Pharmacol. 1950, 5, 37-48 593. HOBBIGER, F. Inhibition of cholinesterases by irreversible inhibitions in vitro and in vivo Brit. J. Pharmacol. 1951, 6, 21-30 594. HOFMANN-CREDNER, D. & SIEDEK, H. Distribution and fate of schradan (bis-dimethylaminophosphorous anhydride) in mammals, using a radioactive compound Arch. int. Pharmacodyn. 1952, 89, 74-81 595. JOHNSON, G. M. Toxic effects of tetraethylpyrophosphate J. Fla med. Ass. 1950, 36, 417-419 582 PESTICIDES

596. JONES, H. W., JR., MEYER, B. J. & KAREL, L. The relationship of cholinesterase inhibiting activity to the toxicity of some organic phosphorus compounds J. Pharmacol. 1948, 94, 215-220 597. KONST, H. & PLUMMER, P. J. G. Acute and chronic toxicity of parathion to warm-blooded animals Canad. J. comp. Med. 1950, 14, 90-108 598. KOPPANYI, T., KARCZMAR, A. G. & KING, T. 0. Effect of tetraethyl pyrophosphate on sympathetic ganglionic activity Science, 1947, 106, 492-493 599. MICHAELIS, M. ARANGO, N. I. & GERARD, R. W. Inhibition of brain dehydrogenases by anticholinesterases Amer. J. Physiol. 1949, 157, 463-467 600. PANKASKIE, J. E., FOUNTAINE, F. C. & DAHM, P. A. The degradation and detoxication of parathion in dairy cows J. econ. Ent. 1952, 45, 51-60 601. SALERNO, P. R. & COON, J. M. A pharmacologic comparison of hexaethyl tetraphosphate (HETP) and tetraethyl pyrophosphate (TEPP) with physostigmine, neostigmine and DFP J. Pharmacol. 1949, 95, 240-255 602. SALERNO, P. R. & COON, J. M. Drug protection against the lethal action of parathion Arch. int. Pharmacodyn. 1950, 84, 227-236 603. SALLE, J. Etude pharmacologique sur le thiophosphate de diethyle et de paranitrophenyle (thiophos) Arch. int. Pharmacodyn. 1950, 82, 181-191 604. VALADE, P. Note sur l'anatomie pathologique de l'intoxication experimentale par le thiophos Arch. int. Pharmacodyn. 1950, 84, 360-366 605. VALADE, P. & SALLE, J. Etude pharmacologique et anatomo-pathologique d'un insecticide: le thiophosphate de di-ethyle et de paranitroph6nyle Bull. Acad. vet. Fr. 1950, 23, 255-262 606. VERBEKE, R. On the pharmacology of tetraethylpyrophosphate (TEPP) Arch. int. Pharmacodyn. 1949, 80, 19-27 607. WILLS, J. H., MCNAMARA, B. P. & FINE, E. A. Ventricular fibrillation in delayed treatment of tetraethyl pyrophosphate (TEPP) poisoning Fed. Proc. 1950, 9, 136

F. Herbicides

608. AMBROSE, A. M. Some toxicological and pharmacological studies on 3,5-dinitro-o-cresol J. Pharmacol. 1942, 76, 245-251 EXPERIMENTAL STUDIES - ETUDES EXPERIMENTALES 583

609. BUCHER, N. L. R. Effects of 2,4-dichlorophenoxyacetic acid on experimenta animals Proc. Soc. exp. Biol. (N.Y.), 1946, 63, 204-205 610. Buzzo, A. & GUATELLI, M. A. [Toxicologic study of dinitro-o-cresol (D.N.C.)] Rev. Asoc. bioquim. argent. 1949, 14, No. 68, pp. 24-40 611. PARKER, V. H., BARNES, J. M. & DENZ, F. A. Some observations on the toxic properties of 3:5-dinitro-ortho-cresol Brit. J. industr. Med. 1951, 8, 226-235 612. SCHMIDT, H. W. tiber Dinitro-ortho-Kresol und die daraus hergestellten Pflanzenschutzmittel Pharmazie, 1948, 3, 400-401 613. SPENCER, H. C. et al. Toxicological studies on laboratory animals of certain alkyldinitro-phenols used in agriculture J. industr. Hyg. 1948, 30, 10-25

G. Fungicides G. Fongicides

614. HUNTER, D., BOMFORD, R. R. & RUSSELL, D. S. Poisoning by methyl mercury compounds Quart. J. Med. 1940, n.s, 9, 193-213

H. Rodenticides

615. BARTLETT, G. R. & BARRON, E. S. G. The effect of fluoroacetate on enzymes and on tissue metabolism J. biol. Chem. 1947, 170, 67-82 616. BRION, A. Sur la toxicit6 de I'alpha-naphtyle-thiouree Arch. int. Pharmacodyn. 1949, 80, 301-309 617. BUFFA, P. & PETERS, R. A. Formation of citrate in vivo induced by fluoroacetate poisoning Nature (Lond.), 1949, 163, 914 618. CHENOWETH, M. B. Prevention of fluoroacetate poisoning by acetate donors Fed. Proc. 1949, 8, 280-281 619. CHENOWETH, M. B. & GILMAN, A. Pharmacology of fluoroacetate Fed. Proc. 1946, 5, 171 620. CHENOWETH, M. B. & GILMAN, A. Studies on the pharmacology of fluoroacetate. I. J. Pharmacol. 1946, 87, 90-103 584 PESTICIDES

621. CHENOWETH, M. B. & ST. JOHN, E. F. Studies on the pharmacology of fluoroacetate. III. J. Pharmacol. 1947, 90, 76-82 622. CHENOWETH, M. B. et al. Factors influencing fluoroacetate poisoning. Practical treatment with glycerol monoacetate J. Pharmacol. 1951, 102, 31-49 623. DIEKE, S. H. & RICHTER, C. P. Age and species variation in the acute toxicity of alpha-naphthyl thiourea Proc. Soc. exp. Biol. (N.Y.), 1946, 62, 22-25 624. DRINKER, C. K. & HARDENBERGH, E. Acute effects upon the lungs of dogs of large intravenous doses of alpha-naphthylthiourea (ANTU) Amer. J. Physiol. 1949, 156, 35-43 625. DUBOIS, K. P. & SEBESTA, E. E. The effect of alpha-naphthyl-thiourea on peroxidase and catalase Fed. Proc. 1947, 6, 326 626. FARAH, A., WEST, T. C. & ANGEL, R. The action of sodium fluoroacetate on intestinal smooth muscle J. Pharmacol. 1950, 98, 234-244 627. FITZHUGH, 0. G. & NELSON, A. A. Chronic oral toxicity of alpha-naphthyl-thiourea Proc. Soc. exp. Biol. (N.Y.), 1947, 64, 305-310 628. FLEISCHMANN, W., STUBBS, J. L. & MCSHANE, W. P. Effect of alpha-naphthylthiourea (ANTU) on serum cholesterol in thyroidecto- mized dogs Proc. Soc. exp. Biol. (N.Y.), 1949, 70, 246-248 629. FURCHGOTT, R. F. The effect of sodium fluoroacetate on the contractility and metabolism of intestinal smooth muscle J. Pharmacol. 1950, 99, 1-15 630. HARVEY, T. S., TATUM, H. J. & HIMMELFARB, S. L-Thiosorbitol and BAL as antidotes in phenylthiourea poisoning J. Pharmacol. 1947, 90, 348-350 631. HERRMANN, R. G. & DUBOIS, K. P. Studies on the toxicity and pharmacological action of p-dimethyl-aminobenzene- diazo sodium sulfonate (DAS) J. Pharmacol. 1949, 95, 262-271 632. HERRMANN, R. G. & DUBOIS, K. P. The effect of p-dimethylamino benzenediazo sodium sulfonate (DAS) on the enzymatic reactions of intermediary carbohydrate metabolism J. Pharmacol. 1949, 95, 272-284 633. HESSE, F. E. & LOOSLI, C. G. Lining of alveoli in mice, rats, dogs and frogs following acute pulmonary edema produced by ANTU poisoning Anat. Rec. 1949, 105, 299-323 CONTAMINATION 585

634. HUTCHENS, J. 0. et al. The effect of ethanol and various metabolites on fluoroacetate poisoning J. Pharmacol. 1949, 95, 62-70 635. LIEBECQ, C. & PETERS, R. A. The toxicity of fluoroacetate and the tricarboxylic acid cycle Biochem. biophys. Acta, 1949, 3, 215 636. LILLIE, R. D. Studies on the pharmacologic action and the pathology of alphanaphthylthiourea (ANTU). II. Pub!. Hith Rep. (Wash.), 1945, 60, 1108-1113 637. MCCLOSKY, W. T. & SMITH, M. I. Studies on the pharmacologic action and the pathology of alphanaphthylthiourea (ANTU). I. Publ. Hlth Rep. (Wash.), 1945, 60, 1101-1108 638. MURTHA, E. F. et al. The treatment of sodium fluoroacetate poisoning in dogs and rabbits, Army Chemical Center, Medical Division, Md., USA, 1951 (Medical Division Research Report No. 22, pp. 1-11) 639. TOURTELLOTTE, W. W. & COON, J. M. Treatment of fluoroacetate poisoning in mice and dogs J. Pharmacol. 1951, 101, 82-91 640. WARD, A. A. JR. Convulsive activity induced by fluoroacetate J. Neurophysiol. 1947, 10, 105-111

VII. RESIDUE PROBLEMS AND FOOD CONTAMINATION VII. PROBLtPMES RELATIFS AUX PRODUITS RISIDUELS ET A LA CONTAMINATION DES ALIMENTS

641. BIDDULPH, C. et al. DDT in milk and tissues of dairy cows fed DDT-dusted alfalfa hay In: American Chemical Society, Division of Agricultural and Food Chemistry, Agricultural control chemicals, Washington, D.C., 1950, pp. 237-243 642. BIRK, L. A. & DIXON, S. E. Use of DDT and methoxychlor for housefly and hornfly control with especial reference to residues in milk Rep. ent. Soc. Ont., 1950, 1951, 93-102 643. BRITTIN, W. A. & FAIRING, J. D. Insecticides in canned foods, the effects of processing on spray residue J. Ass. off. agric. Chem. (Wash.), 1950, 33, 599-607 586 PESTICIDES

644. BRYSON, M. J. et al. DDT in eggs and tissues of chickens fed varying levels of DDT In: American Chemical Society, Division of Agricultural and Food Chemistry, Agricultural control chemicals, Washington, D.C., 1950, pp. 232-236 645. BUSHLAND, R. C. et al. Contamination of meat and milk by chlorinated hydrocarbon insecticides.used for livestock pest control J. econ. Ent. 1950, 43, 649-652 646. BUTrERFIELD, D. E., PARKIN, E. A. & GALE, M. M. The transfer of DDT to foodstuffs from impregnated sacking J. Soc. Chem. Ind. (Lond.), 1949, 68, 310-313 647. CARMAN, G. E. et al. Absorption of DDT and Parathion by fruits In: American Chemical Society, Division of Agricultural and Food Chemistry, Agricultural control chemicals, Washington, D.C., 1950, pp. 128-136 648. CAROLLO, J. A. The removal of DDT from water supplies J. Amer. Wat. Wks Ass. 1945, 37, 1310-1317 649. CARTER, R. H. DDT residues in agricultural products Industr. Engng Chem. 1948, 40, 716-717 650. CARTER, R. H. & MANN, H. D. The DDT content of milk from a cow sprayed with DDT J. econ. Ent. 1949, 42, 708 651. CARTER, R. H. et al. Effect of cooking on the DDT content of beef Science, 1948, 107, 347 652. CARTER, R. H. et al. The chlorinated hydrocarbon content of milk sprayed for control of horn flies J. econ. Ent. 1949, 42, 116-118 653. CLABORN, H. V., BECKMAN, H. F. & WELLS, R. W. Contamination of milk from DDT sprays applied to dairy barns J. econ. Ent. 1950, 43, 723-724 654. CLABORN, H. V., BECKMAN, H. F. & WELLS, R. W. Excretion of DDT and TDE in milk from cows treated with these insecticides J. econ. Ent. 1950, 43, 850-852 655. DIXON, S. E. & IRVINE, 0. R. Use of lindane on dairy cattle and in the dairy barn with respect to tainting in cheese Rep. ent. Soc. Ont., 1950, 1951, 102-103 656. DuBois, K. P. Food contamination from the new insecticides J. Amer. diet. Ass. 1950, 26, 325-328 657. ELY, E. R. et al. The effect of dosage level and method of administration of DDT on the concentration of DDT in milk J. Dairy Sci. 1950, 33, 386 CONTAMINATION 587

658. FITZHUGH, 0. G. Use of DDT insecticides on food products Industr. Engng Chem. 1948, 40, 704-705 659. FREAR, D. E. H., BRUCE, W. N. & RAGSDALE, A. C. DDT in milk following barn spraying J. econ. Ent. 1950, 43, 656-657 660. FURMAN, D. P. & HOSKINS, W. M. Benzene hexachloride in cream from cows' milk J. econ. Ent. 1948, 41, 106-107 661. GINSBURG, J. M., FILMER, R. S. & REED, J. P. Longevity of parathion, DDT, and dichlorodiphenyl dichloroethane on field and vegetable crops J. econ. Ent. 1950, 43, 90-94 662. GINSBURG, J. M. et al. Recovery of parathion, DDT and certain analogs from treated crops J. econ. Ent. 1949, 42, 602-611 663. GUNTHER, F. A., BARNES, M. M. & CARMAN, G. E. Removal of DDT and Parathion residues from apples, pears, lemons and oranges In: American Chemical Society, Division of Agricultural and Food Chemistry, Agricultural control chemicals, Washington, D.C., 1950, pp. 137-142 664. HARRIS, H. J., HANSENS, E. J. & ALEXANDER, C. C. Determination of DDT in milk produced in barns sprayed with DDT insecticides Agric. Chemic. 1950, 5, 51 665. HARTZELL, A. Toxicity of spray residue of fresh and processed fruits and vegetables In: American Chemical Society, Division of Agricultural and Food Chemistry, Agricultural control chemicals, Washington, D.C., 1950, pp. 102-107 666. HARWOOD, P. D. Benzene hexachloride and poultry meat Science, 1948, 107, 113 667. HAYWARD, L. A. W. Contamination caused to sacked decorticated groundnuts by direct spraying with aqueous suspensions of BHC and DDT J. Sci. Food Agric. 1951, 2, 524-527 668. HENSILL, G. S. & GARDNER, L. R. Some poisonous residue factors in use of two new organic insecticides In: American Chemical Society, Division of Agricultural and Food Chemistry, Agricultural control chemicals, Washington, D.C., 1950, pp. 102-107 669. HOLMES, E. L. & SALATHE, L. J. Use of residual spray materials in a typical food industry In: American Chemical Society, Division of Agricultural and Food Chemistry, Agricultural control chemicals, Washington, D.C., 1950, pp. 28-30 670. HOSKINS, W. M. Deposit and residue of recent insecticides resulting from various control practices in California J. econ. Ent. 1949, 42, 966-973 671. HOWELL, D. E. et al. The amount of DDT found in the milk of cows following spraying J. Dairy Sci. 1947, 30, 717-721 588 PESTICIDES

672. KNIPLING, E. F. DDT and related insecticides in milk J. Milk Tech. 1950, 13, 283-287 673. LEHMAN, A. J. Some toxicological reasons why certain chemicals may or may not be permitted as food additives Bull. Ass. Fd Drug. Off. 1950, 14, 82-98 674. LEHRER, W. P., BARR, W. F. & MANIS, H. C. Odor and taste of pork from animals sprayed with benzene hexachloride J. Anim. Sci. 1949, 8, 141-143 675. MANALO, G. D., HUFSON, R. & BENNE, E. J. DDT residues on fruits and vegetables Canner, 1946, 103, 10-11, 22; Quart. Bull. Mich. agric. Exp. Sta. 1946, 28, 272 676. MANN, H. D., CARTER, R. H. & ELY, R. E. The DDT content of milk products J. Milk Tech. 1950, 13, 340-341 677. PARKER, J. R. et al. Toxaphene residues, Bozeman, Mont., 1949 (Montana Agricultural Experiment Station, Technical Bulletin No. 461) 678. PETUNIN, F. A., MANZHOS, M. D. & PONOMAREVA, N. L. [Toxicity of feeds sprayed with DDT dust] Veterinarija, 1950, 27, No. 10, pp. 36-37 679. RADELEFF, R. D. et al. Toxaphene residues in fat of sprayed cattle Vet. Med. 1951, 46, No. 8 680. ROBINSON, R. H. Harvest analysis of DDT residues Food Packer, 1948, 29, 50-53 681. ROBINSON, R. H. Spray residues on food crops and their relation to total food consumption In: American Chemical Society, Division of Agricultural and Food Chemistry, Agricultural control chemicals, Washington, D.C., 1950, pp. 49-51 682. SHEPHERD, J. B. et al. The effect of feeding alfalfa hay containing DDT residue on the DDT content of cow milk J. Dairy Sci. 1949, 32, 549-555 683. SMITH, R. F., HOSKINS, W. M. & FULLMER, 0. H. Secretion of DDT in milk of dairy cows fed low-residue alfalfa hay J. econ. Ent. 1948, 41, 759-763 684. SOMADE, B. Contamination and taint of cacao beans by residual insecticides J. Sci. Fd Agric. 1951, 2, 527-528 685. TELFORD, H. S. & GUTHRIE, J. E. Transmission of the toxicity of DDT through the milk of white rats and goats Science, 1945, 102, 647 CONTAMINATION 589

686. WALKER, K. C. Parathion spray residue on soft fruits, apples and pears In: American Chemical Society, Division of Agricultural and Food Chemistry, Agricultural control chemicals, Washington, D.C., 1950, pp. 123-127 687. WESTLAKE, W. E. & FAHEY, J. E. DDT and parathion spray residues on apples In: American Chemical Society, Division of Agricultural and Food Chemistry, Agricultural control chemicals, Washington, D.C., 1950, pp. 117-122 688. WINGO, C. W. & CRISLER, 0. S. Effect of DDT on dairy cattle and milk J. econ. Ent. 1948, 41, 105-106 689. WINTERINGHAM, F. P. W. et al. Fate of labeled insecticide residues in food products. I. Studies with radioactive bromine analog of DDT J. Sci. Food Agric. 1950, 1, 214-219