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Biochemistry of Bio Molecules I 1. Carbohydrates and Glycobiology. 3. Vitamins

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Biochemistry of Bio Molecules I 1. Carbohydrates and Glycobiology. 3. Vitamins SARDAR PATEL UNIVERSITY Vallabh Vidyanagar, Gujarat (Reaccredited with ‘A’ Grade by NAAC (CGPA 3.25) Syllabus with effect from the Academic Year 2021-2022 (Name of the Degree) (Programme Name) (Degree abbreviation) (Programme Name) Semester (Use Roman numerals) Course Code Title of the US03CBCH21 Biochemistry of Bio Molecules I Course Total Credits Hours per 4 4 of the Course Week Course Student should be able to: Objectives: 1. Importance of bio molecules in living cells 2. Chemistry of bio molecules … Course Content Unit Description Weightage* (%) 1. Carbohydrates and glycobiology. 25 Definition, classification and functions of carbohydrates. Occurrence and biochemical roles of monosaccharide. Disaccharides (maltose, sucrose and lactose). Oligosaccharides (Raffinose). Polysaccharides (starch, glycogen, cellulose, heparin). Physical properties – Asymmetric carbon, D and L isomers, isomerism, mutarotation, optical activity, epimers, cyclization. Chemical properties – Osazone formation, action of acids and alkali on sugars Derivatives of Sugars with example. 2. Nucleotide and Nucleic acids: 25 1. Functions and composition of nucleic acids 2. Structure of nucleotides, purines and pyrimidines. 3. Nomenclature of nucleotides. 4. DNA (a) Structure of DNA. (b) DNA double helix (Watson and crick model). (c) Chargaff’s rule of DNA compositions. (d) Different forms of DNA (Double Helix). (e) The size of DNA. (f) Organization of DNA in the cell. (g) Denaturation & Renaturation of DNA strands. 3. Vitamins 25 Definition & Classification of Water soluble and fat soluble vitamins. Sources, chemical nature (without structure) functions of vitamins. Roles of Coenzymes 4. Minerals 25 Definition& classification Macro and Micro minerals - their sources, RDA. Page 1 of 3 SARDAR PATEL UNIVERSITY Vallabh Vidyanagar, Gujarat (Reaccredited with ‘A’ Grade by NAAC (CGPA 3.25) Syllabus with effect from the Academic Year 2021-2022 Role of Minerals as Co-factor ( biochemical reaction) General Functions of Minerals. Disorders of Macro Minerals. Teaching- Topics will be taught and discussed in interactive sessions using Learning conventional black board and chalk as well as ICT tools such as power Methodology point presentations and videos. Practical sessions will be conducted in a suitably equipped laboratory either individually or in groups depending on the nature of exercise as well as availability of infrastructure. Course materials will be provided from primary and secondary sources of information. Evaluation Pattern Sr. Details of the Evaluation Weightage No. 1. Internal Written / Practical Examination (As per CBCS R.6.8.3) 15% 2. Internal Continuous Assessment in the form of Practical, Viva-voce, 15% Quizzes, Seminars, Assignments, Attendance (As per CBCS R.6.8.3) 3. University Examination 70% Course Outcomes: Having completed this course, the learner will be able to 1. Understanding of bio molecules and their involment in living cells. Suggested References: Sr. References No. 1. Biochemistry Mathews –Van Holde. Fundamentals of biochemistry Dr. J.L Jain, Dr.Sanjay Jain. Nitin Jain. Textbook of medical biochemistry :7th Edition – Rana Shinde, M.N. Page 2 of 3 SARDAR PATEL UNIVERSITY Vallabh Vidyanagar, Gujarat (Reaccredited with ‘A’ Grade by NAAC (CGPA 3.25) Syllabus with effect from the Academic Year 2021-2022 Chatterjea Outlines of Biochemistry Eric E. Conn, Paul k. Stumpf, George Bruening Roy H. Doi Biochemistry U.Satayanarayana, U Chakrapani. Textbook of Biochemistry for medical students RAFI MD. Zubay’s Principles of biochemistry VeerBala Rastogi K.R. Aneja. Textbook of biochemistry for medical students DM. Vasudevan, Sreekumari S. Kannan Vaidyanathan. On-line resources to be used if available as reference material On-line Resources Related References Books ***** Page 3 of 3 SARDAR PATEL UNIVERSITY Vallabh Vidyanagar, Gujarat (Reaccredited with ‘A’ Grade by NAAC (CGPA 3.25) Syllabus with effect from the Academic Year 2021-2022 (Name of the Degree) (Programme Name) (Degree abbreviation) (Programme Name) Semester (Use Roman numerals) Course Code Title of the BIOPHYSICAL US03CBCH22 Course BIOCHEMISTRY Total Credits Hours per 4 4 of the Course Week Course 1. Should have knowledge about universal solvent, water. Objectives: 2.Acid base balance 3. should know radio isotopes … Course Content Unit Description Weightage* (%) 1. UNIT-1 WATER:- 25 1) Structure and solvent properties. 2) Colligative properties of water. 3) Distribution of body water. 4) Normal water balance. 5) Regulatory mechanism of normal water balance. A) Role of kidney. B)Thirst mechanism. C) Role of ADH and Aldosterone 6) Abnormal water balance. A) Pure water Dehydration. B) Pure Salt Dehydration. C) Mixed type (water & Salt) Dehydration D) Over hydration. 2. Acid, Base, and Buffer:- 25 1.Definition of Acid, Base, Buffer & pH and pH measurement methods. 2. Physiological Buffer System. A. Intracellular B. Extracellular 3. Titration curve and pka of weak acid 4. H-H equation & its example to find PH and pka 3. Biophysical Biochemistry:- 25 1) Colloid:-Definition & classification of colloids 2) Properties of colloids (in short). (A) Tyndal effect (B) Dialysis (C) Brownian movement (D) Ageing (E) Coagulation (F) Electrical Page 1 of 3 SARDAR PATEL UNIVERSITY Vallabh Vidyanagar, Gujarat (Reaccredited with ‘A’ Grade by NAAC (CGPA 3.25) Syllabus with effect from the Academic Year 2021-2022 Properties. 3) Biological significance of Colloids. 4) Definition & significance of - Viscosity, surface tension, Osmosis, Diffusion, Donnan membrane equilibrium. 4. Radioisotopes 25 1) Introduction of isotopes:-atomic Numbers, mass numbers, isotopes Radioisotopes, unit of radio activity, Half lives of isotopes. Radio acive decay. 2) Techniques used in mesurement of radioactivity:- Principle and method of Autoradiography, Scintillation Counting, Geigermuller Counter. 3) Biological hazards of radiation and its safety. 4) Significances and applications of radio isotopes in various field of Biological science and medical field. ... Teaching- Topics will be taught and discussed in interactive sessions using Learning conventional black board and chalk as well as ICT tools such as power Methodology point presentations and videos. Practical sessions will be conducted in a suitably equipped laboratory either individually or in groups depending on the nature of exercise as well as availability of infrastructure. Course materials will be provided from primary and secondary sources of information. Evaluation Pattern Sr. Details of the Evaluation Weightage No. 1. Internal Written / Practical Examination (As per CBCS R.6.8.3) 15% 2. Internal Continuous Assessment in the form of Practical, Viva-voce, 15% Quizzes, Seminars, Assignments, Attendance (As per CBCS R.6.8.3) 3. University Examination 70% Course Outcomes: Having completed this course, the learner will be able to 1. Understanding of biological buffer and importance of radio isotops. Page 2 of 3 SARDAR PATEL UNIVERSITY Vallabh Vidyanagar, Gujarat (Reaccredited with ‘A’ Grade by NAAC (CGPA 3.25) Syllabus with effect from the Academic Year 2021-2022 Suggested References: Sr. References No. 1. Biophysical Chemistry BY Upadhayay and Nath. 2 Principles of biochemistry – lehninger. 3 Human Physiology By C.C.Chetargy. 4 Hawks biochemistry. On-line resources to be used if available as reference material On-line Resources Related References Books ***** Page 3 of 3 SARDAR PATEL UNIVERSITY Vallabh Vidyanagar, Gujarat (Reaccredited with ‘A’ Grade by NAAC (CGPA 3.25) Syllabus with effect from the Academic Year 2021-2022 (Name of the Degree) (Programme Name) (Degree abbreviation) (Programme Name) Semester (Use Roman numerals) Course Code Title of the US03CBCH23 BIOCHEMISTRY PRACTICAL Course Total Credits Hours per 8 4 of the Course Week Course 1. Ability to apply the fundamental knowledge of carbohydrates. Objectives: 2. Ability to prepare the chemical solutions which are prepare for the practicals. 3. Ability to how to calculate the practical calculation. Course Content Unit Description Weightage* (%) 1. (BIOCHEMISTRY PRACTICAL) 100 • Rules and regulations in a biochemistry • laboratory.Prepration of Normal ,% solution( understanding of practical calculation). • Estimation of Vitamin – C by titrametric method. • Qualitative analysis of carbohydrate. • Quantitative analysis by Beer’s Law / lamda max.( KmnO4) • Estimation of Iron. • Estimation of Phosphorous. Teaching- Practical sessions will be conducted in a suitably equipped laboratory Learning either individually or in groups depending on the nature of exercise as well Methodology as availability of infrastructure. The module will consist of seminars, in which the students will be supported in their practical teaching classes This practical session will also involve them observing their peers and participating in observation tasks and oral feedback. There will be a focus on particular experiment perform by students. Evaluation Pattern Sr. Details of the Evaluation Weightage No. 1. Internal Written / Practical Examination (As per CBCS R.6.8.3) 15% 2. Internal Continuous Assessment in the form of Practical, Viva-voce, 15% Quizzes, Seminars, Assignments, Attendance (As per CBCS R.6.8.3) Page 1 of 3 SARDAR PATEL UNIVERSITY Vallabh Vidyanagar, Gujarat (Reaccredited with ‘A’ Grade by NAAC (CGPA 3.25) Syllabus with effect from the Academic Year 2021-2022 3. University Examination 70% Course Outcomes: Having completed this course, the learner will be able to 1. Understanding of bio chemical analysis and estimation of various
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