Monoclonal Antibody to RAD1 (N-Term) - Purified

OriGene Technologies, Inc. OriGene Technologies GmbH

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AM06054PU-N Monoclonal Antibody to RAD1 (N-term) - Purified

Alternate names: Cell cycle checkpoint protein RAD1, DNA repair exonuclease rad1 homolog, REC1, Rad1-like DNA damage checkpoint protein Quantity: 50 µl Concentration: 1 mg/ml Background: Human Rad1 is a component of a heterotrimeric PCNA-like complex that also contains the Rad9 and Hus1 proteins. This complex is believed to be involved in cellular responses to DNA damage, possibly by associating with Rad17 and several components of the PCNA-loading heteropentamer, replication factor C. Human Rad1 exhibits significant homology to Rad1 from S. pombe, and its expression in yeast rad1 mutants has been shown to partially restore radiation resistance and G2-checkpoint activity. It has also been shown to possess exonuclease activity. Uniprot ID: O60671 NCBI: NP_002844.1 GeneID: 5810 Host / Isotype: Mouse / IgG Clone: 4126 Immunogen: Recombinant protein of human Rad1 purified from E. coli. Epitope: N-Terminus Format: State: Liquid Ig fraction Purification: Protein G column Buffer System: Phosphate buffered saline, pH 7,2 Applications: Immunohistochemistry on Paraffin Sections: 10 µg/ml. Western Blot. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. Specificity: This antibody detects Rad1 (s. Pombe) Homolog (rad1) at N-terminus. Species Reactivity: Tested: Human Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

For research and in vitro use only. Not for diagnostic or therapeutic work. Material Safety Datasheets are available at www.acris-antibodies.com or on request. MS/20170921 1 / 2 AM06054PU-N: Monoclonal Antibody to RAD1 (N-term) - Purified

Pictures: Testis: Formalin-Fixed Paraffin- Embedded (FFPE)

For research and in vitro use only. Not for diagnostic or therapeutic work. Material Safety Datasheets are available at www.acris-antibodies.com or on request. MS/20170921 2 / 2