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Table S2. Mass spectrometry based quantitation (LFQ scores) of co-purifying from yeast with ExoY-TAP.

PEP - posterior error probability - the probability of a false hit given the peptide identification score and length of peptides (defined in Cox, J. & Mann, M. MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide quantitation. Nat Biotechnol. 2008 Dec;26(12):1367-72. doi: 10.1038/nbt.1511.)

LFQ - Label Free Quantitation score - proportional to the average peptide signal intensity for all the peptides used to identify a given . Approximates the relative amounts of protein and can be used to compare protein levels between two conditions.

Uniprot Description Number Number PEP log2(LFQ) log2(LFQ) identifier names of of control TAP-ExoY similar unique identi- peptides fied for proteins protein identify- cation P07342 Acetolactate synthase catalytic subunit, ILV2 1 27 8.77E-214 29.174 26.40759 mitochondrial Q87022 Probable RNA-directed RNA ;Major gag- 4 26 1.42E-267 28.34672 28.81559 ;P32503;Q protein ;gag 87024 P25605 Acetolactate synthase small subunit, ILV6 1 14 7.28E-99 28.14865 25.68654 mitochondrial P23172; Probable RNA-directed RNA polymerase;Major gag- 216 1.63E-75 25.06163 20.40561 Q87026 capsid protein pol;gag P02994 1-alpha TEF1 1 14 1.47E-75 24.22957 25.30567 P10591 Heat shock protein SSA1 SSA1 2 8 2.54E-173 23.31451 25.41361 P04147 Polyadenylate-binding protein, cytoplasmic and PAB1 126 1.06E-95 23.29782 23.92488 nuclear Q00955 Acetyl-CoA carboxylase;Biotin carboxylase ACC1 2 44 1.54E-164 23.02989 20.97337 P0C2I6;P0 Transposon Ty1-LR3 Gag-Pol polyprotein;Capsid TY1B- 57 3 1.88E-88 22.48395 23.64713 C2I9;P0C2 protein;Ty1 protease;Integrase; Reverse LR3;TY1B- J1;P47098 transcriptase/ H (Rev. t./r. PR1;TY1B- ;Q03434; H);Transposon Ty1-PR1 Gag-Pol polyprotein;Capsid PR3;TY1B- Q03612;P protein;Ty1 protease;Integrase;Rev. t./r. JR1;TY1B- 0C2I3;P0C H;Transposon Ty1-PR3 Gag-Pol polyprotein;Capsid ML2;TY1B 2I5;P0C2I7 protein;Ty1 protease;Integrase;Rev. t./r. - ;Q12414;P H;Transposon Ty1-JR1 Gag-Pol polyprotein;Capsid ER1;TY1B- 0C2J0;P47 protein;Ty1 protease;Integrase;Rev. t./r. DR6;TY1B- 100;Q121 H;Transposon Ty1-ML2 Gag-Pol polyprotein;Capsid LR2;TY1B- 41;P0C2I2; protein;Ty1 protease;Integrase;Rev. t./r. LR4;TY1B- Q12269;Q H;Transposon Ty1-ER1 Gag-Pol polyprotein;Capsid PL;TY1B- 12273;Q0 protein;Ty1 protease;Integrase;Rev. t./r. PR2;TY1B- 4711;Q07 H;Transposon Ty1-DR6 Gag-Pol polyprotein;Capsid JR2;TY1B- 793;O135 protein;Ty1 protease;Integrase;Rev. t./r. GR1;TY1B- 35;Q0467 H;Transposon Ty1-LR2 Gag-Pol polyprotein;Capsid DR5;TY1B- 0;Q92393; protein;Ty1 protease;Integrase;Rev. t./r. GR2;TY1B- Q03855;Q H;Transposon Ty1-LR4 Gag-Pol polyprotein;Capsid OL;TY1B- 12193;Q0 protein;Ty1 protease;Integrase;Rev. t./r. ML1;TY1B 3619;Q12 H;Transposon Ty1-PL Gag-Pol polyprotein;Capsid - 088;Q123 protein;Ty1 protease;Integrase;Rev. t./r. DR4;TY1B- 16;Q9923 H;Transposon Ty1-PR2 Gag-Pol polyprotein;Capsid H;TY1B- 1;Q99337; protein;Ty1 protease;Integrase;Rev. t./r. MR2;TY1B O13527 H;Transposon Ty1-JR2 Gag-Pol polyprotein;Capsid -OR;TY1B- protein;Ty1 protease;Integrase;Rev. t./r. DR1;TY1B- H;Transposon Ty1-GR1 Gag-Pol polyprotein;Capsid BR;TY1B- protein;Ty1 protease;Integrase;Rev. t./r. ER2;TY1B- H;Transposon Ty1-DR5 Gag-Pol polyprotein;Capsid LR1;TY1B- protein;Ty1 protease;Integrase;Rev. t./r. GR3;TY1B- H;Transposon Ty1-GR2 Gag-Pol polyprotein;Capsid DR3;TY1B- protein;Ty1 protease;Integrase;Rev. t./r. NL2;TY1B- H;Transposon Ty1-OL Gag-Pol polyprotein;Capsid A protein;Ty1 protease;Integrase;Rev. t./r. H;Transposon Ty1-ML1 Gag-Pol polyprotein;Capsid protein;Ty1 protease;Integrase;Rev. t./r. H;Transposon Ty1-DR4 Gag-Pol polyprotein;Capsid protein;Ty1 protease;Integrase;Rev. t./r. H;Transposon Ty1-H Gag-Pol polyprotein;Capsid protein;Ty1 protease;Integrase;Rev. t./r. H;Transposon Ty1-MR2 Gag-Pol polyprotein;Capsid protein;Ty1 protease;Integrase;Rev. t./r. H;Transposon Ty1-OR Gag-Pol polyprotein;Capsid protein;Ty1 protease;Integrase;Rev. t./r. H;Transposon Ty1-DR1 Gag-Pol polyprotein;Capsid protein;Ty1 protease;Integrase;Rev. t./r. H;Transposon Ty1-BR Gag-Pol polyprotein;Capsid protein;Ty1 protease;Integrase;Rev. t./r. H;Transposon Ty1-ER2 Gag-Pol polyprotein;Capsid protein;Ty1 protease;Integrase;Rev. t./r. H;Transposon Ty1-LR1 Gag-Pol polyprotein;Capsid protein;Ty1 protease;Integrase;Rev. t./r. H;Transposon Ty1-GR3 Gag-Pol polyprotein;Capsid protein;Ty1 protease;Integrase;Rev. t./r. H;Transposon Ty1-DR3 Gag-Pol polyprotein;Capsid protein;Ty1 protease;Integrase;Rev. t./r. H;Transposon Ty1-NL2 Gag-Pol polyprotein;Capsid protein;Ty1 protease;Integrase;Rev. t./r. H;Truncated transposon Ty1-A Gag-Pol polyprotein;Integrase;Rev. t./r. H P32324 Elongation factor 2 EFT1 1 22 2.20E-91 22.08787 22.89421 P00925 Enolase 2 ENO2 1 8 1.53E-72 21.85441 21.80104 P00359; Glyceraldehyde-3-phosphate dehydrogenase TDH3;T 27 7.95E-37 21.84782 22.01522 P00358 3;Glyceraldehyde-3-phosphate dehydrogenase 2 DH2 P04385 GAL1 2 18 5.97E-76 21.82209 22.63668 P00560 Phosphoglycerate PGK1 1 16 1.19E-66 21.61827 21.80589 P06634 ATP-dependent RNA DED1 DED1 2 21 2.06E-100 21.53521 23.9657 P00549 1 CDC19 213 1.88E-48 21.5243 22.82557 P04911; Histone H2A.1;Histone H2A.2 HTA1;H 2 2 2.44E-13 21.33527 23.03391 P04912 TA2 P53865 Chaotic nuclear migration protein 67 CNM67 1 14 1.26E-58 21.33473 18.91132 Q06010 A-factor-processing STE23 116 9.44E-48 21.10815 17.92515 P38011 Guanine nucleotide-binding protein subunit beta- ASC1 1 9 1.99E-40 21.10764 22.89462 like protein P04397 Bifunctional protein GAL10;UDP-glucose 4- GAL10 119 2.75E-89 21.02168 22.0254 epimerase;Aldose 1-epimerase P02309 Histone H4 HHF1 1 5 1.95E-57 20.83399 22.83389 P09624 Dihydrolipoyl dehydrogenase, mitochondrial LPD1 1 9 8.46E-43 20.80971 17.60161 P15646 rRNA 2-O-methyltransferase fibrillarin NOP1 1 9 2.04E-37 20.74435 22.4207 P0C0V8 40S S21-A;40S ribosomal RPS21A 26 2.32E-25 20.70016 21.91138 ;Q3E754 protein S21-B ;RPS21B P32473 Pyruvate dehydrogenase E1 component subunit PDB1 1 5 9.33E-22 20.61495 17.82488 beta, mitochondrial P0CX53; 60S ribosomal protein L12-A;60S ribosomal RPL12A; 27 1.25E-55 20.59696 23.06067 P0CX54 protein L12-B RPL12B P38631 1,3-beta-glucan synthase component FKS1 FKS1 1 12 7.93E-95 20.54576 21.86302 P10080 Single-stranded nucleic acid-binding protein SBP1 1 9 1.73E-26 20.53241 22.00898 P00330 Alcohol dehydrogenase 1 ADH1 38 2.40E-34 20.49921 20.72783 P32905; 40S ribosomal protein S0-A;40S ribosomal protein RPS0A; 2 7 3.89E-26 20.47833 22.33535 P46654 S0-B RPS0B P39990 13 kDa ribonucleoprotein-associated protein SNU13 1 5 5.61E-16 20.44374 21.45443 P46784; 40S ribosomal protein S10-B;40S ribosomal RPS10B 23 5.05E-15 20.42008 22.01591 Q08745 protein S10-A ;RPS10A P05030; Plasma membrane ATPase 1;Plasma membrane PMA1;P 2 15 2.06E-64 20.41183 20.51326 P19657 ATPase 2 MA2 O14467 Multiprotein-bridging factor 1 MBF1 17 2.28E-25 20.31307 20.78429 P38701 40S ribosomal protein S20 RPS20 1 4 1.96E-28 20.23608 21.08083 P12695 Dihydrolipoyllysine-residue acetyltransferase LAT1 1 5 1.07E-19 20.194 17.39632 component of pyruvate dehydrogenase complex, mitochondrial P04840 Mitochondrial outer membrane protein porin 1 POR1 1 10 1.42E-39 20.03604 21.43959 P16387 Pyruvate dehydrogenase E1 component subunit PDA1 15 9.63E-30 20.0084 17.99899 alpha, mitochondrial P24276 Protein SSD1 SSD1 130 3.39E-103 19.99673 22.49865 P37292 Serine hydroxymethyltransferase, mitochondrial SHM1 1 8 2.68E-62 19.83686 19.71453 P00950 Phosphoglycerate mutase 1 GPM1 1 8 2.32E-29 19.79983 19.73945 P32380 Spindle pole body component 110 SPC110 1 9 8.93E-33 19.79425 17.33769 Q01560 Nucleolar protein 3 NPL3 17 4.66E-25 19.78982 21.26774 P02400 60S acidic ribosomal protein P2-beta RPP2B 1 3 4.51E-48 19.58632 21.95642 P41940 Mannose-1-phosphate guanyltransferase PSA1 1 7 1.27E-23 19.57917 19.40279 P0CX49; 60S ribosomal protein L18-A;60S ribosomal RPL18A; 2 5 1.69E-71 19.57723 22.5724 P0CX50 protein L18-B RPL18B P10592 Heat shock protein SSA2 SSA2 2 7 2.63E-167 19.51324 21.71695 P08431 Galactose-1-phosphate uridylyltransferase GAL7 1 11 2.36E-45 19.47799 20.72692 P14832 Peptidyl-prolyl cis-trans CPR1 1 5 1.06E-19 19.44996 18.86912 P0CX23; 60S ribosomal protein L20-A;60S ribosomal RPL20A; 26 9.24E-28 19.42597 22.3531 P0CX24 protein L20-B RPL20B P0CX55; 40S ribosomal protein S18-A;40S ribosomal RPS18A 2 8 7.74E-40 19.33604 21.74891 P0CX56 protein S18-B ;RPS18B P04456 60S ribosomal protein L25 RPL25 15 1.49E-21 19.30354 21.98329 P15992 Heat shock protein 26 HSP26 1 6 2.20E-23 19.23121 19.40949 P21373 NAD(+) kinase UTR1 1 9 4.43E-51 19.04695 20.59377 P0CX82; 60S ribosomal protein L19-A;60S ribosomal RPL19A; 2 5 6.33E-53 19.04033 21.96877 P0CX83 protein L19-B RPL19B Q12499 Nucleolar protein 58 NOP58 1 14 2.71E-53 19.03023 21.85605 Q12159 RNA annealing protein YRA1 YRA1 1 7 1.38E-26 19.01947 21.25084 P02406 60S ribosomal protein L28 RPL28 1 4 3.02E-11 18.98782 21.02817 P32445 Single-stranded DNA-binding protein RIM1, RIM1 1 4 2.54E-13 18.97418 19.36329 mitochondrial P02407; 40S ribosomal protein S17-A;40S ribosomal RPS17A 2 4 5.48E-47 18.9605 21.31744 P14127 protein S17-B ;RPS17B P32787 Mitochondrial genome maintenance protein MGM1 14 3.54E-14 18.95359 19.76912 MGM101 01 P05317 60S acidic ribosomal protein P0 RPP0 1 9 1.09E-33 18.93509 23.51797 P0C2H6 60S ribosomal protein L27-A;60S ribosomal RPL27A; 2 5 1.82E-19 18.8845 21.94292 ;P0C2H7 protein L27-B RPL27B P53540 Spindle pole body component SPC98 SPC98 1 6 2.02E-20 18.86354 17.44484 P14126 RPL3 1 14 6.01E-65 18.85881 22.7163 P05750 RPS3 1 11 2.86E-65 18.84745 22.05186 P0CX37; 40S -A;40S ribosomal protein RPS6A; 26 1.29E-32 18.75104 21.54628 P0CX38 S6-B RPS6B Q12464 RuvB-like protein 2 RVB2 1 6 9.85E-21 18.64005 18.73994 P10659 S-adenosylmethionine synthase 1 SAM1 2 7 8.22E-27 18.63297 19.72815 P06367; 40S ribosomal protein S14-A;40S ribosomal RPS14A 25 9.91E-22 18.58692 21.04527 P39516 protein S14-B ;RPS14B P46672 GU4 nucleic-binding protein 1 ARC1 1 6 2.58E-51 18.56454 19.13142 P41277; (DL)-glycerol-3- 1;(DL)-glycerol-3- RHR2;H 2 8 2.49E-23 18.56223 20.06131 P40106 phosphatase 2 OR2 P34760 Peroxiredoxin TSA1 TSA1 2 5 2.18E-13 18.43925 18.36824 P38199 Heterogeneous nuclear rnp K-like protein 2 HEK2 1 9 1.17E-44 18.23327 20.78955 P02992 Elongation factor Tu, mitochondrial TUF1 1 11 5.52E-43 18.22708 20.74731 P26783 RPS5 17 3.33E-52 18.1318 21.73289 Q12460 Nucleolar protein 56 NOP56 1 18 3.42E-101 18.0388 22.15672 P10664; -A;60S ribosomal protein RPL4A; 2 12 1.50E-72 17.45932 23.43212 P49626 L4-B RPL4B P06105 Protein SCP160 SCP160 141 8.57E-164 17.192 22.82336 P46655 Glutamate--tRNA , cytoplasmic GUS1 1 14 1.74E-49 16.85221 20.78253 P25694 division control protein 48 CDC48 1 11 1.39E-44 16.82848 20.37539 P33322 H/ACA ribonucleoprotein complex subunit 4 CBF5 1 9 2.66E-65 16.73331 21.54165 P06169 Pyruvate decarboxylase isozyme 1 PDC1 3 10 2.32E-25 16.70307 21.29188 P25555 Single-strand telomeric DNA-binding protein GBP2 GBP2 111 7.28E-36 16.03047 20.32641 P60010 Actin ACT1 1 5 3.10E-97 14.81843 25.84986 P43597 Uncharacterized protein YFR016C YFR016 1 27 5.43E-153 0 22.79303 C P07259 Protein URA2;Glutamine-dependent carbamoyl- URA2 246 8.87E-141 0 22.24435 phosphate synthase;Aspartate carbamoyltransferase P22137 Clathrin heavy chain CHC1 131 2.13E-134 0 21.82664 P29453 -B RPL8B 1 3 1.66E-121 0 22.78031 Q9I1S4 ExoY 1 19 1.91E-109 0 26.19191 P39935 Eukaryotic 4F subunit p150 TIF4631 1 17 6.71E-105 0 20.75768 P53622 Coatomer subunit alpha COP1 123 1.30E-104 0 21.7613 P16140 V-type proton ATPase subunit B VMA2 1 18 8.99E-95 0 21.37039 P22147 5-3 1 KEM1 1 28 7.13E-90 0 21.88528 P53254 U3 small nucleolar RNA-associated protein 22 UTP22 1 18 4.36E-83 0 21.26699 P46367 Potassium-activated aldehyde dehydrogenase, ALD4 113 4.55E-79 0 21.05841 mitochondrial P0CX35; 40S ribosomal protein S4-A;40S ribosomal protein RPS4A; 2 10 2.11E-75 0 21.39692 P0CX36 S4-B RPS4B Q05022 rRNA biogenesis protein RRP5 RRP5 119 7.80E-75 0 20.26797 P15108 ATP-dependent molecular chaperone HSC82 HSC82 1 4 1.23E-73 0 21.61077 P24783 ATP-dependent RNA helicase DBP2 DBP2 1 9 1.18E-68 0 19.27296 P41810 Coatomer subunit beta SEC26 1 13 1.04E-67 0 20.30073 P33892 Translational activator GCN1 GCN1 117 1.13E-67 0 19.41353 Q06440 Coronin-like protein CRN1 117 2.63E-67 0 23.41158 P02829 ATP-dependent molecular chaperone HSP82 HSP82 1 2 1.16E-65 0 16.32418 P08518 DNA-directed RNA polymerase II subunit RPB2 RPB2 1 13 1.03E-64 0 19.38646 P40047 Aldehyde dehydrogenase 5, mitochondrial ALD5 1 9 8.93E-64 0 19.83328 P34160 Nuclear cap-binding protein complex subunit 1 STO1 116 7.48E-63 0 20.65744 P16521 Elongation factor 3A YEF3 2 16 8.43E-63 0 21.26247 P19882 Heat shock protein 60, mitochondrial HSP60 1 16 4.74E-59 0 20.85163 P39727 ER-derived vesicles protein ERV46 ERV46 1 5 7.16E-59 0 18.92871 P10964 DNA-directed RNA polymerase I subunit RPA190 RPA190 118 8.45E-58 0 19.90121 P48164 -B RPS7B 13 3.07E-56 0 20.55225 P39960 GTPase-activating protein BEM2/IPL2 BEM2 1 19 8.05E-56 0 20.2573 P40989 1,3-beta-glucan synthase component GSC2 GSC2 1 2 4.52E-55 0 16.70604 P39985 DNA polymerase V POL5 1 9 6.49E-55 0 18.66195 P48589 40S ribosomal protein S12 RPS12 16 1.74E-54 0 21.74234 P38934 Nuclear segregation protein BFR1 BFR1 1 12 8.01E-53 0 20.35154 P47079 T-complex protein 1 subunit theta CCT8 1 12 8.18E-52 0 20.38269 P38249 Eukaryotic initiation factor 3 subunit A RPG1 1 19 4.30E-51 0 20.8112 P15424 ATP-dependent RNA helicase MSS116, MSS116 110 4.93E-48 0 20.19196 mitochondrial P32558 FACT complex subunit SPT16 SPT16 1 11 2.70E-46 0 19.19801 P13517 F-actin-capping protein subunit beta CAP2 1 9 3.23E-46 0 20.91517 Q03690 Clustered mitochondria protein 1 CLU1 115 3.81E-46 0 20.09533 P27692 elongation factor SPT5 SPT5 1 13 4.00E-46 0 19.67086 P26786 40S ribosomal protein S7-A RPS7A 1 3 1.22E-44 0 20.63307 P00924 Enolase 1 ENO1 1 2 1.67E-44 0 17.70435 P53131 Pre-mRNA-splicing factor ATP-dependent RNA PRP43 17 5.53E-44 0 18.9173 helicase PRP43 Q06685 Inositol hexakisphosphate and diphosphoinositol- VIP1 1 14 1.73E-43 0 19.97225 pentakisphosphate kinase P32074 Coatomer subunit gamma SEC21 1 12 3.03E-43 0 19.98593 P0CX43; 60S ribosomal protein L1-A;60S ribosomal protein RPL1A; 29 3.19E-43 0 21.99286 P0CX44 L1-B RPL1B P06103 initiation factor 3 subunit B PRT1 1 13 2.24E-41 0 20.69464 P19524 Myosin-2 MYO2 2 14 5.63E-41 0 18.83846 P05319 60S acidic ribosomal protein P2-alpha RPP2A 13 6.15E-41 0 21.54038 Q03640 Tricalbin-3 TCB3 1 9 3.10E-40 0 19.69556 Q03441 Sporulation protein RMD1 RMD1 1 9 3.49E-40 0 18.91756 Q04225 assembly protein RRB1 RRB1 1 8 1.96E-38 0 19.73965 P22138 DNA-directed RNA polymerase I subunit RPA135 RPA135 112 2.93E-38 0 19.8614 P04449; 60S ribosomal protein L24-A;60S ribosomal RPL24A; 2 4 4.57E-38 0 21.0561 P24000 protein L24-B RPL24B P07149 Fatty acid synthase subunit beta;3- FAS1 19 1.61E-37 0 18.66678 hydroxypalmitoyl-[acyl-carrier-protein] dehydratase;Enoyl-[acyl-carrier-protein] reductase [NADH];[Acyl-carrier-protein] acetyltransferase;[Acyl-carrier-protein] malonyltransferase;S-acyl fatty acid synthase P38764 26S proteasome regulatory subunit RPN1 RPN1 1 5 7.78E-37 0 17.65676 Q12466 Tricalbin-1 TCB1 1 11 1.78E-36 0 18.88062 P39077 T-complex protein 1 subunit gamma CCT3 111 2.70E-36 0 20.52974 P40069 Importin subunit beta-4 KAP123 18 2.72E-36 0 18.68945 P32892 ATP-dependent RNA helicase DRS1 DRS1 1 8 6.84E-36 0 18.47183 P05755; -B;40S ribosomal protein RPS9B; 2 11 6.94E-36 0 21.9636 O13516 S9-A RPS9A P47068 Myosin tail region-interacting protein MTI1 BBC1 19 7.67E-36 0 18.86318 P16861 6- subunit alpha PFK1 1 12 1.22E-35 0 19.78886 P39078 T-complex protein 1 subunit delta CCT4 1 7 5.57E-35 0 18.99339 P38788 Ribosome-associated complex subunit SSZ1 SSZ1 1 11 2.16E-34 0 20.10546 P39730 Eukaryotic translation initiation factor 5B FUN12 111 7.74E-34 0 19.92225 P07703 DNA-directed RNA I and III subunit RPC40 1 8 3.87E-33 0 19.54721 RPAC1 P05739 -B RPL6B 1 3 3.90E-33 0 22.28325 Q04067 Eukaryotic translation initiation factor 3 subunit G TIF35 14 5.57E-33 0 17.89646 P22803 Thioredoxin-2 TRX2 1 4 5.63E-33 0 18.68852 P40991 Putative ribosomal RNA methyltransferase Nop2 NOP2 1 10 2.66E-32 0 20.4997 P27476 Nuclear localization sequence-binding protein NSR1 1 11 3.21E-32 0 20.44668 P36008 Elongation factor 1-gamma 2 TEF4 14 6.01E-32 0 18.18161 P53914 UPF0202 protein KRE33 KRE33 19 3.01E-31 0 19.03752 P34163 Sterol TGL1 TGL1 1 8 9.24E-31 0 18.93557 P38968 Protein transport protein SEC31 SEC31 1 10 9.37E-31 0 19.5097 Q08208 Nucleolar protein 12 NOP12 1 9 1.25E-30 0 19.54195 P15303 Protein transport protein SEC23 SEC23 110 1.64E-30 0 19.18042 P35207 Antiviral helicase SKI2 SKI2 1 6 2.73E-30 0 16.88548 P21954 Isocitrate dehydrogenase [NADP], mitochondrial IDP1 1 8 3.84E-30 0 19.45469 P38828 Protein LSM12 LSM12 1 9 1.01E-29 0 19.67618 P33442 40S ribosomal protein S1-A RPS1A 12 1.09E-29 0 18.80974 P39940 E3 ubiquitin-protein ligase RSP5 RSP5 1 10 1.23E-29 0 18.9394 P0CX41; 60S ribosomal protein L23-A;60S ribosomal RPL23A; 2 2 1.59E-29 0 19.65202 P0CX42 protein L23-B RPL23B P16474 78 kDa glucose-regulated protein homolog KAR2 16 2.10E-29 0 18.33529 P05738; -A;60S ribosomal protein RPL9A; 2 7 2.49E-29 0 21.92915 P51401 L9-B RPL9B P36041 Protein EAP1 EAP1 1 5 2.97E-29 0 18.21939 P50109 Protein PSP2 PSP2 111 5.13E-29 0 20.16349 P14540 Fructose-bisphosphate aldolase FBA1 1 7 6.00E-29 0 21.02303 P36049 rRNA-processing protein EBP2 EBP2 1 6 7.62E-29 0 17.85842 P32571 Ubiquitin carboxyl-terminal 4 DOA4 1 6 8.64E-29 0 18.31831 P25379 Catabolic L-serine/threonine dehydratase;L-serine CHA1 18 1.06E-28 0 18.90865 dehydratase;L-threonine dehydratase P43585 Vacuolar transporter chaperone 2 VTC2 1 8 1.16E-28 0 18.36973 P25293 Nucleosome assembly protein NAP1 1 5 1.23E-28 0 19.47718 P26785 60S ribosomal protein L16-B RPL16B 1 4 1.25E-28 0 21.55201 P21576 Vacuolar protein sorting-associated protein 1 VPS1 17 1.30E-28 0 17.81284 P0CX51; 40S ribosomal protein S16-A;40S ribosomal RPS16A 2 6 2.03E-28 0 20.78788 P0CX52 protein S16-B ;RPS16B P42945 U3 small nucleolar RNA-associated protein 10 UTP10 1 11 2.48E-28 0 18.46431 Q04373 Pumilio homology domain family member 6 PUF6 17 3.12E-28 0 18.9986 Q03973 High mobility group protein 1 HMO1 1 3 4.18E-28 0 18.23706 P30771 ATP-dependent helicase NAM7 NAM7 1 6 5.07E-28 0 18.01313 Q02326 60S ribosomal protein L6-A RPL6A 1 3 7.47E-28 0 20.014 Q08965 Ribosome biogenesis protein BMS1 BMS1 1 10 7.53E-28 0 18.78593 P38996 Nuclear polyadenylated RNA-binding protein 3 NAB3 18 9.50E-28 0 19.08696 P41811 Coatomer subunit beta SEC27 19 1.11E-27 0 20.64948 Q03532 ATP-dependent RNA helicase HAS1 HAS1 1 8 2.94E-27 0 19.28145 P39685 Nucleoporin POM152 POM15 1 9 6.04E-27 0 18.40869 2 P29311 Protein BMH1 BMH1 12 1.00E-26 0 18.74678 P23248 40S ribosomal protein S1-B RPS1B 1 2 1.04E-26 0 20.92434 P32861 UTP--glucose-1-phosphate uridylyltransferase UGP1 1 9 6.84E-26 0 19.23893 P10081 ATP-dependent RNA helicase eIF4A TIF1 1 7 1.80E-25 0 18.80763 P26321 RPL5 16 4.78E-25 0 21.29092 P12687 54S ribosomal protein L2, mitochondrial MRP7 1 4 7.29E-25 0 17.66941 Q08972 [NU+] prion formation protein 1 NEW1 1 8 1.15E-24 0 18.45362 P0CX84; 60S ribosomal protein L35-A;60S ribosomal RPL35A; 2 3 1.28E-24 0 20.86831 P0CX85 protein L35-B RPL35B P0CX39; -A;40S ribosomal protein RPS8A; 2 7 2.34E-24 0 21.48075 P0CX40 S8-B RPS8B P38088; Glycine--tRNA ligase 1, mitochondrial GRS1 2 10 2.78E-24 0 21.36901 P38088-2 P04806 -1 HXK1 1 7 5.78E-24 0 19.18638 P17555 Adenylyl cyclase-associated protein SRV2 1 3 8.66E-24 0 17.20486 P38863 Spindle pole body component SPC97 SPC97 1 8 9.82E-24 0 18.50707 P27614 Carboxypeptidase S CPS1 17 1.20E-23 0 18.32382 P02557 Tubulin beta chain TUB2 1 6 1.43E-23 0 19.7668 P04050 DNA-directed RNA polymerase II subunit RPB1 RPO21 1 5 2.72E-23 0 17.41427 P07260 Eukaryotic translation initiation factor 4E CDC33 1 5 3.75E-23 0 20.3673 Q12329 Heat shock protein 42 HSP42 1 6 8.42E-23 0 20.05629 P53550 mRNA-decapping enzyme subunit 2 DCP2 17 1.07E-22 0 18.30251 P20447 ATP-dependent RNA helicase DBP3 DBP3 1 7 1.11E-22 0 19.23458 P34730 Protein BMH2 BMH2 1 2 1.22E-22 0 16.21145 Q06205 FK506-binding protein 4 FPR4 1 4 1.30E-22 0 19.03725 P0CS90 Heat shock protein SSC1, mitochondrial SSC1 27 2.05E-22 0 19.03171 P25567 RNA-binding protein SRO9 SRO9 1 7 2.35E-22 0 20.84621 P37838 Nucleolar protein 4 NOP4 17 5.40E-22 0 18.97603 P40010 Nuclear GTP-binding protein NUG1 NUG1 1 6 7.28E-22 0 18.40856 P12612 T-complex protein 1 subunit alpha TCP1 1 6 1.09E-21 0 18.03591 P25491 Mitochondrial protein import protein MAS5 YDJ1 1 8 1.11E-21 0 20.53051 P32598 Serine/threonine- PP1-2 GLC7 17 2.28E-21 0 19.97071 P26570; Serine/threonine-protein phosphatase PP- PPZ1;PP 2 6 5.39E-21 0 18.57507 P33329 Z1;Serine/threonine-protein phosphatase PP-Z2 Z2 P00931 Tryptophan synthase TRP5 1 2 7.72E-21 0 16.40116 P40485 Phosphatidylinositol 4,5-bisphosphate-binding SLM1 16 8.08E-21 0 18.02896 protein SLM1 P09440 C-1-tetrahydrofolate synthase, MIS1 1 7 1.00E-20 0 18.88414 mitochondrial;Methylenetetrahydrofolate dehydrogenase;Methenyltetrahydrofolate cyclohydrolase;Formyltetrahydrofolate synthetase P54115 Magnesium-activated aldehyde dehydrogenase, ALD6 1 7 1.34E-20 0 18.77629 cytosolic P38922 Protein HRB1 HRB1 1 5 1.60E-20 0 17.36555 P40413 T-complex protein 1 subunit epsilon CCT5 18 2.73E-20 0 19.04719 P36528 54S ribosomal protein L17, mitochondrial MRPL1 1 4 3.70E-20 0 17.7011 7 P31539 Heat shock protein 104 HSP104 1 7 7.56E-20 0 18.44119 P28241 Isocitrate dehydrogenase [NAD] subunit 2, IDH2 15 7.77E-20 0 19.95631 mitochondrial P07280; 40S ribosomal protein S19-A;40S ribosomal RPS19A 2 5 1.26E-19 0 21.28619 P07281 protein S19-B ;RPS19B P32497 Eukaryotic translation initiation factor 3 subunit C NIP1 17 1.38E-19 0 18.58685 P00958 Methionine--tRNA ligase, cytoplasmic MES1 1 7 1.84E-19 0 18.06645 P25635 Periodic tryptophan protein 2 PWP2 1 6 2.69E-19 0 17.82879 P40064 Nucleoporin NUP157 NUP157 1 6 2.73E-19 0 17.55412 P47075 Vacuolar transporter chaperone 4 VTC4 17 3.66E-19 0 18.41208 P05453 Eukaryotic peptide chain GTP- SUP35 1 6 3.73E-19 0 19.39713 binding subunit P05756 40S ribosomal protein S13 RPS13 15 8.08E-19 0 21.16858 P06168 Ketol-acid reductoisomerase, mitochondrial ILV5 1 5 1.02E-18 0 18.2523 P0C0W 40S ribosomal protein S22-A;40S ribosomal RPS22A 2 2 1.39E-18 0 21.04013 1;Q3E7Y3 protein S22-B ;RPS22B Q05518 Protein PAL1 PAL1 16 1.59E-18 0 18.02118 P39015 Suppressor protein STM1 STM1 1 3 2.79E-18 0 18.79706 Q03940 RuvB-like protein 1 RVB1 1 6 2.83E-18 0 19.53136 P09733; Tubulin alpha-1 chain;Tubulin alpha-3 chain TUB1;T 2 6 2.97E-18 0 19.3138 P09734 UB3 P36068 SWI5-dependent HO expression protein 2 SHE2 1 3 3.27E-18 0 18.54608 P0C0X0; 40S ribosomal protein S28-B;40S ribosomal RPS28B 2 2 5.74E-18 0 20.9912 Q3E7X9 protein S28-A ;RPS28A Q05123 Actin-like protein ARP9 ARP9 14 5.86E-18 0 17.32878 P51998 54S ribosomal protein YmL6, mitochondrial YML6 1 2 6.03E-18 0 16.61396 P20459 Eukaryotic translation initiation factor 2 subunit SUI2 1 4 6.13E-18 0 18.08727 alpha Q02354 U3 small nucleolar RNA-associated protein 6 UTP6 16 7.24E-18 0 17.52175 P42846 Protein KRI1 KRI1 1 6 7.53E-18 0 18.37033 P40693 Ribosome biogenesis protein RLP7 RLP7 1 5 1.27E-17 0 18.10636 P41805 60S ribosomal protein L10 RPL10 1 7 1.35E-17 0 19.79943 Q02931 NET1-associated nuclear protein 1 NAN1 17 1.47E-17 0 18.0828 P05748; 60S ribosomal protein L15-A;60S ribosomal RPL15A; 2 6 1.70E-17 0 22.347 P54780 protein L15-B RPL15B P26784 60S ribosomal protein L16-A RPL16A 1 4 2.10E-17 0 19.97911 P43621 Coatomer subunit delta RET2 16 2.17E-17 0 18.88941 P28495 F-actin-capping protein subunit alpha CAP1 14 2.71E-17 0 20.01495 P25443 RPS2 1 6 5.15E-17 0 21.19617 Q02892 Nucleolar GTP-binding protein 1 NOG1 1 7 1.09E-16 0 18.16098 P39936 Eukaryotic initiation factor 4F subunit p130 TIF4632 1 3 1.47E-16 0 17.22562 Q06698 Putative ATP-dependent RNA helicase YLR419W YLR419 14 1.61E-16 0 17.94575 W Q12220 U3 small nucleolar RNA-associated protein 12 DIP2 15 2.56E-16 0 18.19729 P39729 Ribosome-interacting GTPase 1 RBG1 1 5 2.67E-16 0 17.99689 Q12028 AP-1 complex subunit gamma-1 APL4 1 3 2.83E-16 0 16.91053 Q06106 Multiple RNA-binding domain-containing protein MRD1 1 6 3.01E-16 0 17.49091 1 P0C0W 60S ribosomal protein L11-A;60S ribosomal RPL11A; 2 5 3.01E-16 0 21.26138 9;Q3E757 protein L11-B RPL11B P47077 Nucleolar protein 9 NOP9 15 3.14E-16 0 17.39398 P53094 Negative regulator of sporulation MDS3 MDS3 15 5.66E-16 0 17.32668 P0CH08 Ubiquitin-60S ribosomal protein L40;Ubiquitin;60S RPL40A; 3 2 5.87E-16 0 20.18204 ;P0CH09;P ribosomal protein L40;Polyubiquitin;Ubiquitin RPL40B;U 0CG63 BI4 P00942 Triosephosphate isomerase TPI1 1 4 6.24E-16 0 19.11467 P04821 Cell division control protein 25 CDC25 1 6 7.01E-16 0 18.24242 P28000 DNA-directed RNA polymerases I and III subunit RPC19 13 1.44E-15 0 18.69149 RPAC2 P53883 Nucleolar protein 13 NOP13 1 5 1.64E-15 0 17.94358 Q12176 Ribosome biogenesis protein MAK21 MAK21 1 6 1.92E-15 0 17.6447 P36224 Nuclear migration protein JNM1 JNM1 15 1.99E-15 0 18.04532 P38431; Eukaryotic translation initiation factor 5 TIF5 2 4 2.00E-15 0 16.5159 P38431-2 P40513 Mitochondrial acidic protein MAM33 MAM33 1 3 2.47E-15 0 21.09165 P25623 Suppressor of yeast profilin deletion SYP1 15 2.84E-15 0 18.0215 P05626 ATP synthase subunit 4, mitochondrial ATP4 1 4 3.56E-15 0 17.98259 P32634 Negative regulator of sporulation PMD1 PMD1 1 5 3.61E-15 0 16.08059 Q04491 Protein transport protein SEC13 SEC13 1 5 3.73E-15 0 19.10462 Q04119 Endopolyphosphatase PPN1 16 4.13E-15 0 17.73853 P0CX47; 40S ribosomal protein S11-A;40S ribosomal RPS11A 24 5.46E-15 0 21.048 P0CX48 protein S11-B ;RPS11B P49167 60S ribosomal protein L38 RPL38 1 3 6.53E-15 0 19.97533 P53140 Protein RMD9, mitochondrial RMD9 14 6.72E-15 0 16.19618 P38112 ATP-dependent RNA helicase MAK5 MAK5 14 7.07E-15 0 17.5551 P53252 Sphingolipid long chain base-responsive protein PIL1 13 7.40E-15 0 18.1768 PIL1 P32481 Eukaryotic translation initiation factor 2 subunit GCD11 1 5 8.65E-15 0 18.23262 gamma P35191 DnaJ homolog 1, mitochondrial MDJ1 1 5 8.82E-15 0 18.54751 P40217 Eukaryotic translation initiation factor 3 subunit I TIF34 1 4 1.24E-14 0 18.25484 P09064 Eukaryotic translation initiation factor 2 subunit SUI3 1 5 1.42E-14 0 17.60661 beta P29468 Poly(A) polymerase PAP1 1 5 1.48E-14 0 17.47294 Q05946 U3 small nucleolar RNA-associated protein 13 UTP13 1 4 1.57E-14 0 17.68798 P53297 PAB1-binding protein 1 PBP1 1 6 1.92E-14 0 19.4306 P02293; Histone H2B.1;Histone H2B.2 HTB1;H 2 5 2.86E-14 0 22.47167 P02294 TB2 P17255 V-type proton ATPase catalytic subunit VMA1 1 6 3.04E-14 0 18.31615 A; PI-SceI P53617 Protein NRD1 NRD1 14 3.95E-14 0 17.35784 Q08818 Meiotic sister-chromatid recombination protein 6, MSC6 15 8.20E-14 0 17.16231 mitochondrial P30619 Protein transport protein SEC1 SEC1 1 5 9.61E-14 0 17.82171 P32527 Zuotin ZUO1 15 1.25E-13 0 18.30443 P07251 ATP synthase subunit alpha, mitochondrial ATP1 14 1.52E-13 0 17.0898 P40473 Transcriptional acticator POG1 POG1 1 4 1.66E-13 0 17.32122 P40509 Coatomer subunit epsilon SEC28 1 3 3.37E-13 0 18.16133 P38873 Target of rapamycin complex 1 subunit KOG1 KOG1 1 5 3.87E-13 0 17.11248 P04387 Galactose/lactose metabolism regulatory protein GAL80 14 4.43E-13 0 18.04847 GAL80 P32419 Malate dehydrogenase, peroxisomal MDH3 1 2 4.79E-13 0 15.6999 Q06078 U3 small nucleolar RNA-associated protein 21 UTP21 1 5 4.81E-13 0 18.32988 P33314 Inhibitory regulator protein BUD2/CLA2 BUD2 15 5.03E-13 0 16.90982 P21560 Protein CBP3, mitochondrial CBP3 1 3 5.51E-13 0 17.63715 P35189 Transcription initiation factor TFIID subunit 14 TAF14 1 3 5.69E-13 0 18.00163 P06782 Carbon catabolite-derepressing SNF1 1 5 6.18E-13 0 18.50754 Q02725 Vacuolar transporter chaperone 3 VTC3 13 6.91E-13 0 16.51796 P25644 DNA topoisomerase 2-associated protein PAT1 PAT1 1 2 7.02E-13 0 17.52014 P39968 Vacuolar protein 8 VAC8 1 4 7.91E-13 0 17.78162 P39744 Nucleolar complex protein 2 NOC2 1 4 8.10E-13 0 17.51591 Q12275 Uncharacterized protein YOR093C 14 8.37E-13 0 16.15411 Q03088 Styryl dye vacuolar localization protein 3 SVL3 1 3 9.13E-13 0 17.36265 P43620 Sporulation protein RMD8 RMD8 1 4 9.51E-13 0 17.58586 P53378 Tubulin gamma chain TUB4 1 4 1.05E-12 0 18.78995 P40059 Transcriptional regulatory protein DOT6 DOT6 25 1.08E-12 0 18.39645 P53235 Eukaryotic translation initiation factor 2A YGR054 14 1.30E-12 0 17.67542 W P40530 [Pyruvate dehydrogenase [lipoamide]] kinase, PKP1 1 4 1.33E-12 0 16.61296 mitochondrial P07283 Phosphomannomutase SEC53 1 5 1.78E-12 0 17.92799 P53316 Uncharacterized RNA-binding protein YGR250C YGR250 1 5 2.52E-12 0 17.88864 C Q99247 Uncharacterized WD repeat-containing protein 15 2.56E-12 0 16.50449 YOL087C P38696 Centractin ARP1 1 4 3.03E-12 0 19.87503 P32457 Cell division control protein 3 CDC3 1 4 3.77E-12 0 17.38355 Q99288 Putative phosphoglycerate mutase DET1 DET1 14 3.93E-12 0 18.07713 P17967 Protein disulfide-isomerase PDI1 1 4 7.29E-12 0 17.3443 Q06706 Elongator complex protein 1 IKI3 1 3 7.37E-12 0 15.89574 P14065 Protein GCY GCY1 2 4 7.81E-12 0 16.75316 Q06251 Uncharacterized protein YLR177W YLR177 1 2 7.95E-12 0 16.95776 W Q04660 Ribosome biogenesis protein ERB1 ERB1 1 4 8.13E-12 0 18.06028 P38820 Adenylyltransferase and sulfurtransferase UBA4 1 4 8.26E-12 0 17.30697 UBA4;Adenylyltransferase UBA4;Sulfurtransferase UBA4 Q07362 Protein PBP4 PBP4 14 8.78E-12 0 18.0301 P52910 Acetyl-coenzyme A synthetase 2 ACS2 14 9.51E-12 0 17.09042 P41903 Peroxisomal acyl-coenzyme A thioester hydrolase TES1 14 1.72E-11 0 18.20146 1 P53551 Histone H1 HHO1 1 2 2.00E-11 0 16.76901 P00817 Inorganic pyrophosphatase IPP1 12 3.10E-11 0 17.59892 P32790 Actin cytoskeleton-regulatory complex protein SLA1 13 3.40E-11 0 17.19065 SLA1 P53739 Flippase kinase 1 FPK1 1 4 3.41E-11 0 17.64393 Q03653 Protein EFR3 EFR3 13 3.94E-11 0 15.62211 Q12114 Chitin biosynthesis protein CHS5 CHS5 14 4.16E-11 0 17.01465 P28007 H/ACA ribonucleoprotein complex subunit 1 GAR1 1 4 4.42E-11 0 20.90029 P14120 60S ribosomal protein L30 RPL30 1 2 4.79E-11 0 21.52573 P37012; Phosphoglucomutase-2;Phosphoglucomutase-1 PGM2;P 2 4 4.99E-11 0 17.59419 P33401 GM1 P53953 SED5-binding protein 2 SFB2 1 5 5.19E-11 0 17.16172 P40075 Vesicle-associated membrane protein-associated SCS2 1 3 5.21E-11 0 18.34789 protein SCS2 Q12136 Something about silencing protein 10 SAS10 12 5.79E-11 0 16.16031 P25270 rRNA methyltransferase, mitochondrial MRM1 1 3 6.08E-11 0 16.86918 P47116 Serine/threonine-protein kinase PTK2/STK2 PTK2 1 3 6.10E-11 0 16.80423 P32561 Histone deacetylase RPD3 RPD3 1 3 7.16E-11 0 16.91205 P32599 Fimbrin SAC6 13 7.97E-11 0 15.88362 P38250 Increased sodium tolerance protein 2 IST2 1 2 9.10E-11 0 16.02858 Q04409 Putative -2 EMI2 1 4 9.90E-11 0 16.89285 P49166 60S ribosomal protein L37-A RPL37A 1 3 1.05E-10 0 18.92196 Q02866 Protein MUK1 MUK1 1 3 1.09E-10 0 16.23193 P20436 DNA-directed RNA polymerases I, II, and III RPB8 12 1.22E-10 0 17.43567 subunit RPABC3 P40160 Serine/threonine-protein kinase RIO2 RIO2 1 2 1.29E-10 0 14.11789 P36119 Uncharacterized protein YKR023W YKR023 1 5 1.49E-10 0 17.41229 W P53011 Nucleoporin SEH1 SEH1 1 4 1.54E-10 0 18.26463 P43638 MAP-homologous protein 1 MHP1 14 1.66E-10 0 17.01835 P30665 DNA replication licensing factor MCM4 MCM4 1 3 1.70E-10 0 16.48243 P50942 Polyphosphatidylinositol phosphatase INP52 2 4 2.13E-10 0 15.09816 INP52;SAC1-like phosphoinositide phosphatase;Phosphatidylinositol 4,5-bisphosphate 5-phosphatase Q01855 40S ribosomal protein S15 RPS15 1 3 2.21E-10 0 19.63619 P50095; Inosine-5-monophosphate dehydrogenase IMD3;I 4 2 2.29E-10 0 17.08286 P50094;P3 3;Inosine-5-monophosphate dehydrogenase MD4;IMD 8697;P395 4;Inosine-5-monophosphate dehydrogenase 2;IMD1 67 2;Putative inosine-5-monophosphate dehydrogenase 1 P32657 Chromo domain-containing protein 1 CHD1 1 4 2.49E-10 0 16.52636 Q01080 DNA-directed RNA polymerase I subunit RPA49 RPA49 14 2.79E-10 0 17.76267 P32597 Nuclear protein STH1/NPS1 STH1 13 3.22E-10 0 16.49234 P38203 U6 snRNA-associated Sm-like protein LSm2 LSM2 1 2 3.62E-10 0 17.87412 Q03862 Probable metalloprotease ARX1 ARX1 1 3 4.06E-10 0 17.09959 P32349 DNA-directed RNA polymerase III subunit RPC3 RPC82 1 2 4.82E-10 0 15.26323 P36161 Nucleoporin NUP133 NUP133 13 5.93E-10 0 15.97199 P36048 Pre-mRNA-splicing factor SNU114 SNU114 1 2 6.21E-10 0 15.79976 P38882 U3 small nucleolar RNA-associated protein 9 UTP9 1 5 8.23E-10 0 17.62849 P42943 T-complex protein 1 subunit eta CCT7 1 3 8.36E-10 0 16.84928 P23641 Mitochondrial phosphate carrier protein MIR1 14 8.42E-10 0 18.35767 P39079 T-complex protein 1 subunit zeta CCT6 13 9.85E-10 0 16.70361 Q12754 Ribosomal RNA-processing protein 12 RRP12 1 4 1.04E-09 0 16.60924 P19097 Fatty acid synthase subunit alpha;Acyl carrier;3- FAS2 1 2 1.05E-09 0 15.73582 oxoacyl-[acyl-carrier-protein] reductase;3-oxoacyl- [acyl-carrier-protein] synthase O14455 60S ribosomal protein L36-B;60S ribosomal RPL36B; 2 2 1.10E-09 0 18.99882 ;P05745 protein L36-A RPL36A P53691 Peptidyl-prolyl cis-trans isomerase CPR6 CPR6 1 3 1.15E-09 0 17.98588 P40212; 60S ribosomal protein L13-B;60S ribosomal RPL13B; 2 3 1.22E-09 0 20.50048 Q12690 protein L13-A RPL13A P46951 Cargo-transport protein YPP1 YPP1 1 3 1.35E-09 0 16.75421 P04807 Hexokinase-2 HXK2 1 3 1.36E-09 0 16.95345 P41318 Target of rapamycin complex subunit LST8 LST8 1 3 1.36E-09 0 16.4165 P32501 Translation initiation factor eIF-2B subunit epsilon GCD6 15 1.73E-09 0 17.37696 Q03048 Cofilin COF1 1 3 1.81E-09 0 19.05436 P29366 Bud emergence protein 1 BEM1 1 3 1.86E-09 0 15.47358 P38061 60S ribosomal protein L32 RPL32 1 3 2.10E-09 0 18.97679 P34227 Mitochondrial peroxiredoxin PRX1 PRX1 13 2.29E-09 0 17.90595 P00830 ATP synthase subunit beta, mitochondrial ATP2 13 2.56E-09 0 16.69914 P53276 U3 small nucleolar RNA-associated protein 8 UTP8 1 4 2.72E-09 0 16.80713 P39938; 40S ribosomal protein S26-A;40S ribosomal RPS26A 2 3 2.89E-09 0 19.69396 P39939 protein S26-B ;RPS26B Q04305 U3 small nucleolar RNA-associated protein 15 UTP15 13 3.58E-09 0 17.99004 P39676 Flavohemoprotein YHB1 1 2 3.73E-09 0 15.07602 P18239 ADP,ATP carrier protein 2 PET9 3 3 3.91E-09 0 17.37067 P0C2H9 60S ribosomal protein L31-B;60S ribosomal RPL31B; 2 3 4.22E-09 0 21.10744 ;P0C2H8 protein L31-A RPL31A P25368 Ribosomal RNA-processing protein 7 RRP7 1 4 4.43E-09 0 17.6182 P0C0T4; 40S ribosomal protein S25-B;40S ribosomal RPS25B 2 3 4.53E-09 0 19.5685 Q3E792 protein S25-A ;RPS25A P21242 Proteasome component C1 PRE10 12 4.54E-09 0 15.84439 P38720 6-phosphogluconate dehydrogenase, GND1 2 5 4.56E-09 0 17.60444 decarboxylating 1 P36531 54S ribosomal protein L36, mitochondrial MRPL3 1 2 4.67E-09 0 15.97421 6 Q06217 Small nuclear ribonucleoprotein Sm D2 SMD2 1 3 5.42E-09 0 17.47825 P32565 26S proteasome regulatory subunit RPN2 RPN2 1 3 5.81E-09 0 15.65158 P14742 Glucosamine--fructose-6-phosphate GFA1 1 3 6.05E-09 0 16.83984 aminotransferase [isomerizing] Q06631 Protein BFR2 BFR2 1 2 6.91E-09 0 16.10161 Q12024 Ribosome biogenesis protein YTM1 YTM1 12 7.84E-09 0 16.80625 P36036 RNA annealing protein YRA2 YRA2 1 3 9.32E-09 0 17.97079 P17709 Glucokinase-1 GLK1 1 2 1.13E-08 0 16.75994 Q12522 Eukaryotic translation initiation factor 6 TIF6 1 3 1.17E-08 0 19.42403 Q07800 Phosphatase PSR1 PSR1 13 1.18E-08 0 16.45079 Q12496 Uncharacterized protein YOL098C 1 4 1.26E-08 0 17.33141 P40561 RNA-binding protein SGN1 SGN1 1 3 1.32E-08 0 18.39603 P47130 Cop9 signalosome complex subunit 12 CSN12 1 3 1.49E-08 0 15.86916 Q12230 Sphingolipid long chain base-responsive protein LSP1 12 1.50E-08 0 16.01863 LSP1 Q06488 Chromatin structure-remodeling complex subunit RSC2 1 3 1.84E-08 0 17.3944 RSC2 P12385 Eukaryotic peptide chain release factor subunit 1 SUP45 13 1.99E-08 0 17.82383 P19454 Casein kinase II subunit alpha CKA2 1 3 2.02E-08 0 17.25654 P07170 1 ADK1 1 3 2.25E-08 0 15.46068 P0CX45; 60S ribosomal protein L2-A;60S ribosomal protein RPL2A; 2 3 2.93E-08 0 20.08226 P0CX46 L2-B RPL2B P38708 Putative proline--tRNA ligase YHR020W YHR020 1 3 3.70E-08 0 16.74136 W P36520 54S ribosomal protein L10, mitochondrial MRPL1 1 3 4.05E-08 0 16.32948 0 P53261 Pescadillo homolog NOP7 1 3 5.62E-08 0 17.1563 Q99257 mRNA export factor MEX67 MEX67 1 3 6.18E-08 0 16.53261 P40557 ER-retained PMA1-suppressing protein 1 EPS1 1 3 6.66E-08 0 15.52662 Q08920 Nuclear cap-binding protein subunit 2 CBC2 13 8.40E-08 0 16.65746 P32505 Nuclear polyadenylated RNA-binding protein NAB2 13 9.12E-08 0 16.97891 NAB2 Q06218 ATP-dependent RNA helicase DBP9 DBP9 1 3 9.33E-08 0 15.89491 P13185 Serine/threonine protein kinase KIN1 KIN1 12 9.34E-08 0 16.00492 P23337; Glycogen [starch] synthase isoform 1;Glycogen GSY1;G 22 9.37E-08 0 16.29606 P27472 [starch] synthase isoform 2 SY2 Q03735 RNA-binding protein NAB6 NAB6 1 3 1.39E-07 0 19.70068 Q02821 Importin subunit alpha SRP1 12 1.60E-07 0 16.41723 Q12019 Midasin MDN1 1 3 1.61E-07 0 16.25927 P38911 FK506-binding nuclear protein FPR3 1 2 1.63E-07 0 17.64174 P25298 mRNA 3-end-processing protein RNA14 RNA14 1 3 1.71E-07 0 17.8104 Q6Q547 H/ACA ribonucleoprotein complex subunit 3 NOP10 13 1.84E-07 0 18.43884 P38164 WD repeat-containing protein YBL104C 1 3 1.86E-07 0 16.14386 P22217 Thioredoxin-1 TRX1 1 2 2.01E-07 0 16.71478 P32449; Phospho-2-dehydro-3-deoxyheptonate aldolase, ARO4;A 2 2 2.03E-07 0 15.74578 P14843 tyrosine-inhibited;Phospho-2-dehydro-3- RO3 deoxyheptonate aldolase, phenylalanine-inhibited P36120 ATP-dependent RNA helicase DBP7 DBP7 1 2 2.15E-07 0 15.30567 P41057 40S ribosomal protein S29-A RPS29A 1 2 2.21E-07 0 17.02215 P43586 60S ribosomal subunit assembly/export protein LOC1 1 2 2.30E-07 0 17.0441 LOC1 Q04599 54S ribosomal protein L1, mitochondrial MRPL1 1 3 2.32E-07 0 17.05918 P38065 AP-2 complex subunit alpha APL3 1 3 2.32E-07 0 15.53518 P32908 Structural maintenance of protein SMC1 1 2 2.66E-07 0 15.35875 1 P34077 Nucleoporin NIC96 NIC96 1 2 2.77E-07 0 15.67984 P53741 UBP3-associated protein BRE5 BRE5 1 3 2.85E-07 0 16.08161 Q12389 ATP-dependent RNA helicase DBP10 DBP10 1 3 2.93E-07 0 15.89487 P53250 Twinfilin-1 TWF1 13 3.39E-07 0 16.6485 P46956 Inorganic phosphate transporter PHO86 PHO86 1 3 3.92E-07 0 17.30305 P13181 Galactose transporter GAL2 1 2 4.13E-07 0 17.40133 P22579 Transcriptional regulatory protein SIN3 SIN3 1 2 4.44E-07 0 15.32499 Q04439 Myosin-5 MYO5 1 3 4.49E-07 0 15.34246 Q08096 RNA 3-terminal phosphate cyclase-like protein RCL1 13 4.77E-07 0 17.45153 Q08831 Protein VTS1 VTS1 1 2 4.88E-07 0 16.6277 Q03761 Transcription initiation factor TFIID subunit 12 TAF12 1 3 4.97E-07 0 15.0044 P53881 54S ribosomal protein L22, mitochondrial MRPL2 1 3 5.47E-07 0 16.68975 2 P07253 Cytochrome B pre-mRNA-processing protein 6 CBP6 12 6.26E-07 0 15.89114 P41058 40S ribosomal protein S29-B RPS29B 1 2 6.26E-07 0 15.91401 P89105 RNA polymerase-associated protein CTR9 CTR9 1 2 7.07E-07 0 15.53226 P39931 Protein SSP120 SSP120 1 2 7.26E-07 0 16.82637 P32495 H/ACA ribonucleoprotein complex subunit 2 NHP2 12 7.35E-07 0 19.70506 P25655 General negative regulator of transcription CDC39 1 4 7.52E-07 0 16.42833 subunit 1 P28274 CTP synthase 1 URA7 1 2 7.55E-07 0 18.36871 Q03063 Down-regulator of invasive growth 1 DIG1 12 9.75E-07 0 16.72707 P36534 54S ribosomal protein L40, mitochondrial MRPL4 1 2 1.07E-06 0 16.03896 0 P13382 DNA polymerase alpha catalytic subunit A POL1 1 3 1.14E-06 0 15.68992 Q12117 Protein MRH1;Protein YRO2 MRH1;Y 22 1.14E-06 0 17.46786 ;P38079 RO2 P28834 Isocitrate dehydrogenase [NAD] subunit 1, IDH1 1 2 1.14E-06 0 16.79411 mitochondrial Q12517 mRNA-decapping enzyme subunit 1 DCP1 13 1.22E-06 0 17.48652 P32500 Nucleoporin NDC1 NDC1 1 2 1.28E-06 0 14.96934 Q07807 mRNA-binding protein PUF3 PUF3 1 2 1.29E-06 0 16.09044 P38970 Serine/threonine-protein kinase HAL5 HAL5 1 2 1.32E-06 0 15.90741 P20606 Small COPII coat GTPase SAR1 SAR1 12 1.33E-06 0 15.89855 P16550 Protein APA1;5,5-P-1,P-4-tetraphosphate APA1 1 3 1.40E-06 0 17.2275 ;ADP-sulfurylase P40483 Putative zinc YIL108W YIL108 1 2 1.43E-06 0 15.96034 W P20081 FK506-binding protein 1 FPR1 12 1.51E-06 0 16.98181 P38879 Nascent polypeptide-associated complex subunit EGD2 1 2 1.55E-06 0 17.06855 alpha P10962 Protein MAK16 MAK16 12 1.61E-06 0 15.9281 Q07623 Nucleolar protein 6 NOP6 13 1.73E-06 0 17.62792 P38626 NADH-cytochrome b5 reductase 1 CBR1 1 2 1.81E-06 0 17.34126 P33750 Protein SOF1 SOF1 1 2 1.90E-06 0 15.17687 P35997; 40S ribosomal protein S27-A;40S ribosomal RPS27A 22 2.11E-06 0 20.9636 P38711 protein S27-B ;RPS27B P47018 Maintenance of telomere capping protein 1 MTC1 1 2 2.39E-06 0 15.47656 Q12377 26S proteasome regulatory subunit RPN6 RPN6 12 2.78E-06 0 15.75384 P11745 Ran GTPase-activating protein 1 RNA1 12 2.82E-06 0 16.81341 P22146 1,3-beta-glucanosyltransferase GAS1 GAS1 1 2 2.85E-06 0 16.17617 P32589; Heat shock protein homolog SSE1;Heat shock SSE1;SS 2 2 2.98E-06 0 16.05877 P32590 protein homolog SSE2 E2 P06786 DNA topoisomerase 2 TOP2 13 2.99E-06 0 16.47733 P20448 ATP-dependent RNA helicase HCA4 HCA4 1 2 3.06E-06 0 15.9621 Q12250 26S proteasome regulatory subunit RPN5 RPN5 1 2 3.26E-06 0 15.15885 Q08235 Ribosome biogenesis protein BRX1 BRX1 1 2 3.28E-06 0 17.47175 P31383 Protein phosphatase PP2A regulatory subunit A TPD3 12 3.29E-06 0 15.31281 Q02959 Histone deacetylase HOS3 HOS3 1 2 3.30E-06 0 16.5868 P38809 Uncharacterized protein YHR097C YHR097 1 2 3.32E-06 0 17.16162 C Q06188 PWWP domain-containing protein YLR455W YLR455 12 3.41E-06 0 16.73503 W P38041 Protein BOB1 BOI1 1 2 3.64E-06 0 14.83684 Q01662 Methionine aminopeptidase 1 MAP1 1 2 3.68E-06 0 16.02081 P25342 Cell division control protein 10 CDC10 12 4.11E-06 0 15.6018 Q08925 RNA-binding protein MRN1 MRN1 1 3 4.32E-06 0 17.5092 P38682 ADP-ribosylation factor GTPase-activating protein GLO3 1 2 4.43E-06 0 15.9204 GLO3 P38779 Proteasome-interacting protein CIC1 CIC1 12 4.48E-06 0 17.39573 P32582 Cystathionine beta-synthase CYS4 12 4.54E-06 0 16.03544 Q04697 Glucose-signaling factor 2 GSF2 1 2 4.92E-06 0 15.99086 P53538 RNA polymerase II subunit A C-terminal domain SSU72 1 2 4.95E-06 0 16.8516 phosphatase SSU72 Q12000 Translation machinery-associated protein 46 TMA46 12 5.48E-06 0 16.73317 P40327 26S protease regulatory subunit 4 homolog RPT2 1 2 5.82E-06 0 15.71971 P43603 LAS seventeen-binding protein 3 LSB3 13 5.87E-06 0 15.76319 P23301 Eukaryotic translation initiation factor 5A-1 HYP2 1 2 6.27E-06 0 17.08182 P40070 U6 snRNA-associated Sm-like protein LSm4 LSM4 1 2 6.81E-06 0 17.1801 P52286 Suppressor of kinetochore protein 1 SKP1 1 2 7.28E-06 0 15.95826 P35178 Ribosomal RNA-processing protein 1 RRP1 12 7.63E-06 0 16.64779 P35691 Translationally-controlled tumor protein homolog TMA19 1 2 8.46E-06 0 17.12948 P40066 Nucleoporin GLE2 GLE2 1 2 8.46E-06 0 14.8555 P33338 Protein SLA2 SLA2 1 2 8.62E-06 0 15.17043 P47108 Nucleolar pre-ribosomal-associated protein 2 URB2 12 1.02E-05 0 15.30567 P32502 Translation initiation factor eIF-2B subunit beta GCD7 12 1.02E-05 0 16.4656 P38181 Nucleoporin NUP170 NUP170 1 2 1.03E-05 0 15.34873 Q12324 Calcium channel YVC1 YVC1 1 2 1.05E-05 0 15.43869 P16370 DNA-directed RNA polymerase II subunit RPB3 RPB3 1 3 1.19E-05 0 16.31812 P45818 ATP-dependent RNA helicase ROK1 ROK1 12 1.23E-05 0 14.95837 P45976 Pre-mRNA factor FIP1 FIP1 1 2 1.26E-05 0 16.50129 P36124 SET domain-containing protein 3 SET3 1 2 1.33E-05 0 15.54457 P36160 Ribosome biogenesis protein RPF2 RPF2 1 2 1.42E-05 0 14.93521 P12709 Glucose-6-phosphate isomerase PGI1 12 1.53E-05 0 16.97118 Q12034 Protein SLF1 SLF1 12 1.90E-05 0 15.25074 P53941 U3 small nucleolar ribonucleoprotein protein IMP4 1 2 1.97E-05 0 15.59968 IMP4 P07257 Cytochrome b-c1 complex subunit 2, QCR2 12 1.99E-05 0 14.55645 mitochondrial P46995 Histone-lysine N-methyltransferase, H3 lysine-36 SET2 1 3 2.02E-05 0 14.81483 specific P0CX31; 40S ribosomal protein S24-A;40S ribosomal RPS24A 22 2.06E-05 0 18.41448 P0CX32 protein S24-B ;RPS24B P11075 Protein transport protein SEC7 SEC7 1 3 2.21E-05 0 14.33839 P48362 FAM203 family protein HGH1 HGH1 1 2 2.23E-05 0 13.38343 P32388 54S ribosomal protein MRP49, mitochondrial MRP49 12 2.41E-05 0 17.3177 P29295 Casein kinase I homolog HRR25 HRR25 1 2 2.82E-05 0 16.26536 P25847 DNA mismatch repair protein MSH2 MSH2 12 2.90E-05 0 15.3214 Q01477 Ubiquitin carboxyl-terminal hydrolase 3 UBP3 1 2 3.17E-05 0 16.21964 P39107 Mannan polymerase complexes subunit MNN9 MNN9 1 2 3.40E-05 0 16.25923 Q08287 60S ribosome subunit biogenesis protein NOP8 NOP8 1 2 3.82E-05 0 16.20021 Q06505 Transcription factor SPN1 SPN1 12 3.87E-05 0 16.29273 P39076 T-complex protein 1 subunit beta CCT2 1 2 4.22E-05 0 14.9312 Q03780 Uncharacterized protein YDR239C YDR239 1 2 4.25E-05 0 14.84422 C Q06833 Uncharacterized PH domain-containing protein YPR091 12 4.42E-05 0 14.65765 YPR091C C P32588 Nuclear and cytoplasmic polyadenylated RNA- PUB1 1 2 5.01E-05 0 17.27531 binding protein PUB1 Q12339 rRNA-processing protein UTP23 UTP23 12 5.06E-05 0 15.29419 P24583 Protein kinase C-like 1 PKC1 1 2 5.67E-05 0 14.18022 Q02793 Antiviral protein SKI8 SKI8 1 2 5.89E-05 0 15.10987 P33201 mRNA turnover protein 4 MRT4 1 2 6.00E-05 0 16.82352 Q02486 ARS-binding factor 2, mitochondrial ABF2 12 6.42E-05 0 18.08903 P25374 Cysteine desulfurase, mitochondrial NFS1 1 2 7.05E-05 0 16.09356 P06704 Cell division control protein 31 CDC31 1 2 7.63E-05 0 17.4758 P23644 Mitochondrial import receptor subunit TOM40 TOM40 1 2 7.69E-05 0 16.49149 P36006 Myosin-3 MYO3 1 2 8.36E-05 0 15.53394 P48415 COPII coat assembly protein SEC16 SEC16 12 9.93E-05 0 16.73211 Q12296 Protein MAM3 MAM3 1 2 0.00010305 0 13.26138 Q99177 Pre-mRNA-splicing factor BRR1 BRR1 1 2 0.00013427 0 15.40331 P21339 Morphogenesis-related protein MSB1 MSB1 1 2 0.00013536 0 14.91882 P47017 Sm-like protein LSm1 LSM1 12 0.00015813 0 16.75042 P39969 Protein BOI2 BOI2 1 2 0.00016851 0 14.58467 P61830 Histone H3 HHT1 1 2 0.00017279 0 20.84537 Q06406 U6 snRNA-associated Sm-like protein LSm6 LSM6 1 2 0.00018109 0 18.01236 P38853 Kelch repeat-containing protein 1 KEL1 1 2 0.00018222 0 15.59403 P40018 Small nuclear ribonucleoprotein-associated SMB1 12 0.00020202 0 14.1616 protein B P25303 DnaJ-related protein SCJ1 SCJ1 1 2 0.00021341 0 16.02711 P32364 Kinesin-related protein SMY1 SMY1 1 2 0.00021999 0 15.32685 P22204; Cell cycle protein kinase DBF2;Serine/threonine- DBF2;D 2 2 0.00025432 0 15.61664 P32328 protein kinase DBF20 BF20 P47006 DNA-directed RNA polymerase I subunit RPA34 RPA34 1 2 0.00026572 0 16.61022 P08566 Pentafunctional AROM polypeptide;3- ARO1 1 2 0.00027625 0 16.23973 dehydroquinate synthase;3-phosphoshikimate 1- carboxyvinyltransferase;;3- dehydroquinate dehydratase;Shikimate dehydrogenase P47054 Nucleoporin NUP192 NUP192 1 2 0.00052701 0 16.06158 P35732 RNA polymerase II degradation factor 1 DEF1 1 2 0.00061583 0 15.01807 P14741 Translation initiation factor eIF-2B subunit alpha GCN3 1 2 0.00066697 0 15.96932 Q00416 Helicase SEN1 SEN1 12 0.00070554 0 16.95787 P53207 U1 small nuclear ribonucleoprotein component SNU71 1 2 0.00087532 0 13.37137 SNU71 P43555 Protein EMP47 EMP47 1 2 0.00097409 0 18.86293 Q02979 Glycerophosphodiester GDE1 GDE1 12 0.0014045 0 14.2719 P48234 Ribosome biogenesis protein ENP2 ENP2 12 0.0014827 0 14.7472 P32899 U3 small nucleolar ribonucleoprotein protein IMP3 1 2 0.0015084 0 15.86689 IMP3 P39998 Enhancer of mRNA-decapping protein 3 EDC3 12 0.0015497 0 15.5864 P40525; 60S ribosomal protein L34-B;60S ribosomal RPL34B; 22 0.0017643 0 20.13006 P87262 protein L34-A RPL34A P25357 Probable DNA-binding protein SNT1 SNT1 1 2 0.0018718 0 14.27954 Q12018 Cell division control protein 53 CDC53 12 0.0021173 0 16.20071 P32618 Uncharacterized protein YEL043W 12 0.003124 0 14.78918