Anti-WIPF1 Monoclonal Antibody (DCABH-201724) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

Anti-WIPF1 monoclonal antibody (DCABH-201724) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Antigen Description This gene encodes a protein that plays an important role in the organization of the actin cytoskeleton. The encoded protein binds to a region of Wiskott-Aldrich syndrome protein that is frequently mutated in Wiskott-Aldrich syndrome, an X-linked recessive disorder. Impairment of the interaction between these two proteins may contribute to the disease. Two transcript variants encoding the same protein have been identified for this gene.

Immunogen A synthetic peptide of human WIPF1 is used for rabbit immunization.

Isotype IgG

Source/Host Rabbit

Species Reactivity Human

Purification Protein A

Conjugate Unconjugated

Applications WB, ELISA

Size 1 mg

Buffer In 1x PBS, pH 7.4

Preservative None

Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

GENE INFORMATION

Gene Name WIPF1 WAS/WASL interacting protein family, member 1 [ Homo sapiens (human) ]

Official Symbol WIPF1

Synonyms WIPF1; WAS/WASL interacting protein family, member 1; WIP; PRPL-2; WASPIP; WAS/WASL- interacting protein family member 1; protein PRPL-2; WASP-interacting protein; Wiskott-Aldrich syndrome protein interacting protein;

Entrez Gene ID 7456

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

UniProt ID O43516

Chromosome Location 2q31.1

Pathway Fc-epsilon receptor I signaling in mast cells; Fcgamma receptor (FCGR) dependent phagocytosis; Immune System; Innate Immune System; Regulation of actin dynamics for phagocytic cup formation;

Function actin binding; profilin binding; protein binding;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]