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Syphilis and Other Treponematoses (Clinical and Treatment)

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Syphilis and Other Treponematoses (Clinical and Treatment) Br J Vener Dis: first published as 10.1136/sti.60.5.352 on 1 October 1984. Downloaded from Br J Vener Dis 1984; 60:352-6 Abstracts These selected abstracts and titlesfrom the world literature are arranged in thefollowing sections: Syphilis and other treponematoses (clinical and Trichomoniasis treatment; serology and biologicalfalsepositive Candidosis phenomenon; pathology and experimental) Genital herpes Gonorrhoea (clinical; microbiology; treatment) Other sexually transmitted diseases Chlamydial infections Public health and social aspects Non-specific genital infection Miscellaneous Reiter's disease and midline lumber pain that was worse and a prolonged transit time. The illness Syphilis and other when lying supine. Five months before subsided without treatment after four days. treponematoses (clinical and admission she had a non-itchy dry rash on Similar episodes occurred during the treatment) her trunk and extremities, with lesions following year at four to eight week between five and 15 mm in diameter. intervals. Clinical findings on admission were of After one year he was found to have Penicillin treatment of early syphilis II diminished position sense in the lower perianal and mouth ulcers, hair loss, JF MAHONEY, RC ARNOLD, BL STERNER, ET AL extremities and increased pinprick sense hearing loss with tinnitus, and blurred (Staten Island, New York, USA). JAMA below the T5 dermatone. Muscle tone in the vision with papilloedema. A Venereal 1984; 251:2005-10. legs was also diminished. She had an Disease Research Laboratory (VDRL) test extensor plantar response on the left. The gave a positive result at a titre of 1/64. His Penicillin and early syphilis cranial nerves and arms gave normal results cerebrospinal fluid (CSF) showed: cells HL ARNOLD (Honolulu, Hawaii, USA). to neurological tests. 124 x 106/1 (all lymphocytes), protein con- JAMA 1984; 251: 2011-3. A sample of cerebrospinal fluid was centration 0 39 g/l, and a positive VDRL obtained, and test results showed: total cells test result. A biopsy of a perianal ulcer 259 x 106/1 with 74% lymphocytes; showed treponemes on silver staining, but Eight years experience of cephradine in protein concentration 2 34 g/l. For some an intestinal biopsy, although showing the treatment of syphilis reason no tests for syphilis were performed. villous atrophy and inflammatory cells in A THEODORIDIS, A VAGENA, A VARELZIDIS, Her leg weakness became a flaccid para- the lamina propria, showed no treponemes AND J CAPETANAKIS (University of Athens plegia, and only then was a rapid plasmid either by silver or fluorescent staining. http://sti.bmj.com/ School of Medicine, Athens, Greece). reagin test performed, which gave a positive He was given 20 MU penicillin a day for Current Therapeutic Research 1984; result. A Venereal Disease Research 10 days with steroid cover initially. After 12 35:184-7. Laboratory test on the CSF then gave a days' treatment his CSF cell count was positive result with a titre of 1/16. normal but the VDRL test result remained Secondary syphilis mimicking systemic She was given intravenous penicillin (but positive. Two months after treatment a lupus erythematosus no quantity or duration is stated or whether small bowel biopsy had reverted to nearly to cover a normal. Further questioning disclosed that DM SKILLRUD AND TW BUNCH (Mayo Clinic, any steroids were given possible Rochester, Minnesota, USA). Arthritis Herxheimer reaction) and made a partial he had a cold sore in a nasiolabial fold two on October 1, 2021 by guest. Protected copyright. 26: 1529-31. recovery, her position sense remaining months before his illness began, which had Rheum 1983; impaired. The authors also discuss different healed spontaneously. This is a very rare treatment regimens for neurosyphilis. manifestation of secondary syphilis. Transverse myelitis due to GD Morrison G D Morrison meningovascular syphilis EP HARRIGAN, TJ McLAUGHLIN, AND RG Syphilitic enteritis FELDMAN (Boston University School of D SCHLOSSBERG, FR RUDY, FW JACKSON, AND Syphilis (pathology and Medicine, Boston, Massachusetts, USA). LB DUMALAG (Polyclinic Medical Center, Arch Neurol 1984;41:337-8. Harrisburg, Pennsylvania, USA). Arch experimental) Intern Med 1984;144:811-4. The authors describe the case of a 51 yea r Immunisation of rabbits with Spirochaeta old woman admitted to hospital with a on e The authors report the history of a 40 year aurantia does not induce resistance to month history of constipation, urinar)y old man who complained of passing four to Treponema pallidum retention, and overflow, and a two weekk six watery stools a day and of fever, nausea, S GRAVES, L DRUMMOND, AND R STRUGNELL history of numbness in the buttockrs and vomiting. The stools did not contain (Monash University Medical School, extending gradually down each leg. She haeI blood or mucus. Barium studies showed Prahran, Victoria, Australia). Sex Transm painful tingling in her feet when walking prominent folds in the upper small bowel Dis 1984;11: 1-5. 352 Br J Vener Dis: first published as 10.1136/sti.60.5.352 on 1 October 1984. Downloaded from Abstracts 353 Rabbits were immunised with viable Spiro- Gonococcal infections in Gabon (Haut- Arthritis in rabbits induced by killed chaeta aurantia, a free living, facultative Ogoove) Neisseria gonorrhoeae and gonococcal anaerobic spirochete that is similar in some F YVERT, JY RIOU, E FROST, AND B IVANOFF lipopolysaccharide biochemical characteristics to Treponema (Centre International de R&herce DL GOLDENBERG, JI REED, AND PA RICE pallidum, a parasitic, microaerophilic Medicale, Franceville, Gabon). Pathol (Boston University School of Medicine, spirochete. Single and multiple immunis- Biol (Paris) 1984; 32: 80-4. Boston, USA). J Rheumatol 1984; 11: 3-8. ations with living S aurantia, with or with- out Freund's incomplete adjuvant, Freund's complete adjuvant, or heat killed T pallidum, were carried out over a four Gonorrhoea (microbiology) Lipopolysaccharide banding patterns of month period. Living S aurantia was Neisseria meningitidis and Neisseria neither toxic nor virulent for rabbits. Antigen detection for the diagnosis of gonorrhoeae Immunised rabbits produced a high level of gonorrhoea TR PARR Jr AND LE BRYAN (University of agglutinating antibody to S aurantia but no WE STAMM, B COLE, C FENNELL, ETAL Calgary, Calgary, Alberta, Canada). J Clin antibody to Tpallidum, as assessed by the (Harborview Medical Center, Seattle, Microbiol 1984; 19:558-60. T pallidum h'emagglutination test. Washington, USA). J Clin Microbiol Immunised rabbits were challenged with 1984; 19:399-403. multiple intradermal inoculations of 100 viable T pallidum (Nichols strain) and Il-lactamase producing Neisseria compared with unimmunised rabbits Rapid confirmatory identification of gonorrhoeae similarly infected. Immunisation with S Neisseria gonorrhoeae with lectins and KG SINGH, G SINGH, P KAUR, SS PANDEY, AND aurantia did not protect against Tpallidum chromogenic substances D PAL (Banaras Hindu University, infection. Thus S aurantia appears not to be DM YAJKO, A CHU, AND WK HADLEY Varanasi, Uttar Pradesh, India). Indian J suitable as a potential vaccine against (University of California, San Francisco, Med Res 1984; 79:337-9. infection with Tpallidum. California, USA). J Clin Microbiol Authors' summary 1984; 19: 380-2. Binding of Neisseria gonorrhoea by lectin Antigenic variation during infection with like receptors on human phagocytes Enumeration of Treponema pallidum cells Neisseria gonorrhoeae: detection of KF KINANE, DM WEIR, CC BLACKWELL, AND FP cultivated in vitro by an enzyme-linked antibodies to surface proteins in sera of WINSTANLEY (University of Edinburgh immunosorbent assay patients with gonorrhoea School of Medicine, Edinburgh, UK). J DL COX, RA MOECKLI, AND KM KEANEY (SRI K ZAK, J-L DIAZ, D JACKSON, AND JE HECKELS Clin Lab Immunol 1984; 13:107-10. International, Menlo Park, California, (Southampton General Hospital, USA). Infect Immun 1984;44:103-6. Southampton, Hants, UK). J Infect Dis 1984; 149:166-74. Validity of an enzyme immunoassay for http://sti.bmj.com/ Efficacy of aztreonam in treatment of detection of Neisseria gonorrhoeae experimental syphilis in rabbits Serum sensitivity of Neisseria antigens CJ PAPASIAN, WR BARTHOLOMEW, AND D SA LUKEHART, S BAKER-ZANDER, AND KK gonorrhoeae: the role of HOLMES (University of Washington, lipopolysaccharide AMSTERDAM (Erie County Laboratory, Seattle, Washington, USA). Antimicrob WM SHAFER, K JOINER, LF GUYMON, ETAL Buffalo, New York, USA). J Clin Agents Chemother 1984;25:390-1. (Emory University School of Medicine, Microbiol 1984; 19:347-50. Atlanta, Georgia, USA). J Infect Dis 1984; 149:175-83. on October 1, 2021 by guest. Protected copyright. Inhibition of anion transport in human Purification and partial characterisation erythrocytes by pilated Neisseria Gonorrhoea (clinical) of the opacity-associated proteins of gonorrhoeae GM WISEMAN, CF MARTIN, AND PJ McNICOL Neisseria gonorrhoeae (University of Manitoba, Winnipeg, Cutaneous gonococcal abscess: a case MS BLAKE AND EC GOTSCHLICH (Rockefeller Manitoba, Canada). Can J Microbiol report University, New York, USA). J Exp Med 1984; 30:52-6. NJ FIUMARA AND R EISEN (Massachusetts 1984; 159:452-61. Department of Public Health, Boston, Massachusetts, USA). Sex Transm Dis 1984; 11: 34-5. Common pathways of invasion of Conservation of peptide structure of outer mucosal barriers by Neisseria gonorrhoeae membrane protein-macro molecular and Neisseria meningitidis complex from Neisseria gonorrhoeae ZA McGEE AND DS STEPHENS
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