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Read More in the Full State of the National Vaccine Plan 2013 Annual U.S. Department of Health and Human Services The State of the National Vaccine Plan 2013 Annual Report Protecting the Nation’s Health through Immunization U.S. Department of Health and Human Services Table of Contents Acronyms and Abbreviations .............................................................................................................. 6 Introduction ........................................................................................................................................ 8 The State of the National Vaccine Plan Annual Report in Context ................................................. 9 Figure 1: Organizational Structure of the National Vaccine Plan ................................................. 10 Progress and Opportunities: Implementing the 2010 National Vaccine Plan .............................. 11 Table 1: The State of the National Vaccine Plan – A Quick Glance .............................................. 13 Success through Collaboration: The National Vaccine Plan ......................................................... 17 Table 2: The 2010 National Vaccine Plan: Responsible Stakeholders .......................................... 19 Goal 1: Develop New and Improved Vaccines .................................................................................. 20 Background ................................................................................................................................... 21 Recent Accomplishments and Progress ........................................................................................ 21 Selected Advances in Vaccine Research and Development ......................................................... 22 New Vaccine Production Techniques and Vaccine Technologies ................................................. 24 SMART Vaccines ............................................................................................................................ 26 Vaccine Research and Development: Doing Better than Nature ................................................. 27 New Business Models for Vaccines Targeting Diseases in Low-income Countries ..................... 28 Overcoming the Complexity of Vaccine Development for Global Health .................................... 30 Goal 2: Enhance the Vaccine Safety System ..................................................................................... 32 Background ................................................................................................................................... 33 Recent Accomplishments and Progress ........................................................................................ 33 Research on the Administration and Use of Different Childhood Rotavirus Vaccines for Ensuring Safety and Effectiveness ............................................................................................................... 35 Examining the Safety of the Childhood Immunization Schedule ................................................. 35 Using Electronic Health Data to Monitor Vaccine Safety ............................................................. 37 Advances in the Science, Surveillance, and Safety of Vaccines .................................................... 40 The Vaccine Safety Data System ................................................................................................... 42 Vaccine Safety: Evidence and Belief ............................................................................................. 44 Goal 3: Support Communications to Enhance Informed Vaccine Decision-Making ........................ 46 Background ................................................................................................................................... 47 Recent Accomplishments and Progress ........................................................................................ 47 The State of the National Vaccine Plan | 2013 Annual Report 3 U.S. Department of Health and Human Services Understanding Adult Vaccine Decision-making: Insights from Recent Research ......................... 50 Vaccines.gov ................................................................................................................................. 51 Understanding Parental Decision-making about Vaccines: A Neglected Research Area ............. 52 Communications and Vaccines ..................................................................................................... 54 Goal 4: Ensure a Stable Supply of, Access to, and Better Use of Recommended Vaccines in the United States .................................................................................................................................... 56 Background ................................................................................................................................... 57 Recent Accomplishments and Progress ........................................................................................ 57 Vaccine Financing ......................................................................................................................... 58 Disease Surveillance and Vaccine Coverage Measurement ......................................................... 59 Health Information Technology for Immunization ....................................................................... 61 Health Care Provider Education and Support ............................................................................... 62 Improving Vaccine Tracking through the Use of New Technologies ............................................ 62 2D Barcodes .................................................................................................................................. 63 HealthMap Vaccine Finder: Helping Adults Find the Vaccines They Need ................................... 64 Lack of Progress in HPV Vaccination: A Crisis of Missed for Cancer Prevention ......................... 66 Integrating Pharmacies into a Public Health Approach to Vaccination ........................................ 68 Is the National Vaccine Plan’s Vision for Immunization Infrastructure a Brave New World for Immunization? .............................................................................................................................. 70 Goal 5: Increase Global Prevention of Death and Disease through Safe and Effective Vaccination .......................................................................................................................................................... 72 Background ................................................................................................................................... 73 Recent Accomplishments and Progress ........................................................................................ 73 Global Collaboration to Improve Health Systems in Africa .......................................................... 74 Vaccine Development for Global Populations .............................................................................. 75 Global Implementation of New and Under-utilized Vaccines (NUVI) .......................................... 75 Expanding Global Access to Influenza Vaccines ........................................................................... 76 MenAfriVac: Saving Lives in Africa through Global Collaboration ................................................ 77 Fulfilling the Potential of Vaccines to Protect Health and Save Lives around the World ............. 79 Global Health Diplomacy and Immunization ................................................................................ 81 The Road Ahead ............................................................................................................................ 82 Conclusion and Future Direction of the National Vaccine Plan ........................................................ 83 Appendices ....................................................................................................................................... 85 Table 3: Progress on the Implementation of the National Vaccine Plan ...................................... 85 The State of the National Vaccine Plan | 2013 Annual Report 4 U.S. Department of Health and Human Services The National Vaccine Advisory Committee (NVAC): Historical Contributions and Recent Accomplishments ........................................................................................................................ 110 Commentary on the National Vaccine Advisory Committee: Historical Contributions and Recent Accomplishments ........................................................................................................................ 119 Healthy People 2020: Status of Immunization and Infectious Disease Goals ............................ 121 Healthy People 2020 Immunization and Infectious Diseases Objective Status ............................. 122 Table 4: Vaccine Preventable Diseases ....................................................................................... 122 Table 5: Antibiotic Use ................................................................................................................ 124 Table 6: Vaccine coverage in children 19-35 months ................................................................. 125 Table 7: Vaccine coverage in kindergartners .............................................................................. 126 Table 8: Vaccine coverage in adolescents .................................................................................
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