Synthetic Cannabinoid Induced Psychosis in a Previously Nonpsychotic Patient
The American Journal on Addictions, 21: 287–288, 2012 Copyright C American Academy of Addiction Psychiatry ISSN: 1055-0496 print / 1521-0391 online DOI: 10.1111/j.1521-0391.2012.00222.x Synthetic Cannabinoid Induced Psychosis in a Previously Nonpsychotic Patient Stephanie Peglow, DO,1 Jessica Buchner, BS, MS III,1 Gregory Briscoe, MD2 1Department of Psychiatry and Behavioral Medicine, Eastern Virginia Medical School, Norfolk, Virginia 2Department of Psychiatry, Hampton Veterans Affairs Medical Center, Hampton, Virginia Synthetic cannabinoids are relatively new substances cannabis,6,7 conventional merchant availability, and poten- that have become rapidly popular among young adults. tially negative health impact, synthetic cannabinoids are Despite their legal status in most states, they are virtually anticipated to be an emerging issue in the field of substance unregulated and unstudied. Nevertheless, recent case stud- abuse. ies have brought new attention to their potentially harmful side effects, such as psychosis, agitation, and withdrawal. This case report examines the acute psychosis displayed CASE REPORT by a psychiatric patient after smoking “Spice,” a substance comprised of various synthetic cannabinoids, on three sep- Mr. G is a 59-year-old Latino male with a history of arate occasions. Furthermore, in comparing this patient’s post-traumatic stress disorder (PTSD) and polysubstance lack of psychotic symptoms after tetrahydrocannabinol abuse. Without a prior history of psychosis, he was admit- (THC) use, to the episodes of psychosis experienced af- ted to the same inpatient psychiatric unit three times over a ter “Spice” consumption this case study explores the pos- period of 60 days for the development of psychotic symp- sibility that synthetic cannabinoids are more potent than toms after smoking “Spice.” The patient has a long history their organic counterpart.
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