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List of New Drugs Approved in India from 1991 to 2000
LIST OF NEW DRUGS APPROVED IN INDIA FROM 1991 TO 2000 S. No Name of Drug Pharmacological action/ Date of Indication Approval 1 Ciprofloxacin 0.3% w/v Eye Indicated in the treatment of February-1991 Drops/Eye Ointment/Ear Drop external ocular infection of the eye. 2 Diclofenac Sodium 1gm Gel March-1991 3 i)Cefaclor Monohydrate Antibiotic- In respiratory April-1991 250mg/500mg Capsule. infections, ENT infection, UT ii)Cefaclor Monohydrate infections, Skin and skin 125mg/5ml & 250mg/5ml structure infections. Suspension. iii)Cefaclor Monohydrate 100mg/ml Drops. iv)Cefaclor 187mg/5ml Suspension (For paediatric use). 4 Sheep Pox Vaccine (For April-1991 Veterinary) 5 Omeprazole 10mg/20mg Short term treatment of April-1991 Enteric Coated Granules duodenal ulcer, gastric ulcer, Capsule reflux oesophagitis, management of Zollinger- Ellison syndrome. 6 i)Nefopam Hydrochloride Non narcotic analgesic- Acute April-1991 30mg Tablet. and chronic pain, including ii)Nefopam Hydrochloride post-operative pain, dental 20mg/ml Injection. pain, musculo-skeletal pain, acute traumatic pain and cancer pain. 7 Buparvaquone 5% w/v Indicated in the treatment of April-1991 Solution for Injection (For bovine theileriosis. Veterinary) 8 i)Kitotifen Fumerate 1mg Anti asthmatic drug- Indicated May-1991 Tablet in prophylactic treatment of ii)Kitotifen Fumerate Syrup bronchial asthma, symptomatic iii)Ketotifen Fumerate Nasal improvement of allergic Drops conditions including rhinitis and conjunctivitis. 9 i)Pefloxacin Mesylate Antibacterial- In the treatment May-1991 Dihydrate 400mg Film Coated of severe infection in adults Tablet caused by sensitive ii)Pefloxacin Mesylate microorganism (gram -ve Dihydrate 400mg/5ml Injection pathogens and staphylococci). iii)Pefloxacin Mesylate Dihydrate 400mg I.V Bottles of 100ml/200ml 10 Ofloxacin 100mg/50ml & Indicated in RTI, UTI, May-1991 200mg/100ml vial Infusion gynaecological infection, skin/soft lesion infection. -
WHO Drug Information Vol. 12, No. 3, 1998
WHO DRUG INFORMATION VOLUME 12 NUMBER 3 • 1998 RECOMMENDED INN LIST 40 INTERNATIONAL NONPROPRIETARY NAMES FOR PHARMACEUTICAL SUBSTANCES WORLD HEALTH ORGANIZATION • GENEVA Volume 12, Number 3, 1998 World Health Organization, Geneva WHO Drug Information Contents Seratrodast and hepatic dysfunction 146 Meloxicam safety similar to other NSAIDs 147 Proxibarbal withdrawn from the market 147 General Policy Issues Cholestin an unapproved drug 147 Vigabatrin and visual defects 147 Starting materials for pharmaceutical products: safety concerns 129 Glycerol contaminated with diethylene glycol 129 ATC/DDD Classification (final) 148 Pharmaceutical excipients: certificates of analysis and vendor qualification 130 ATC/DDD Classification Quality assurance and supply of starting (temporary) 150 materials 132 Implementation of vendor certification 134 Control and safe trade in starting materials Essential Drugs for pharmaceuticals: recommendations 134 WHO Model Formulary: Immunosuppressives, antineoplastics and drugs used in palliative care Reports on Individual Drugs Immunosuppresive drugs 153 Tamoxifen in the prevention and treatment Azathioprine 153 of breast cancer 136 Ciclosporin 154 Selective serotonin re-uptake inhibitors and Cytotoxic drugs 154 withdrawal reactions 136 Asparaginase 157 Triclabendazole and fascioliasis 138 Bleomycin 157 Calcium folinate 157 Chlormethine 158 Current Topics Cisplatin 158 Reverse transcriptase activity in vaccines 140 Cyclophosphamide 158 Consumer protection and herbal remedies 141 Cytarabine 159 Indiscriminate antibiotic -
Fixed Drug Eruption Due to a Cerumenolytic Ear Drop; Hydrogen Peroxide and Boric Acid: a Case Report
ISSN: 2688-8238 DOI: 10.33552/OJOR.2020.04.000577 Online Journal of Otolaryngology and Rhinology Case Report Copyright © All rights are reserved by Akif İşlek Fixed Drug Eruption Due to A Cerumenolytic Ear Drop; Hydrogen Peroxide and Boric Acid: A Case Report Akif İşlek1* and Engin Karaaslan2 1Nusaybin State Hospital, Otolaryngology-Head & Neck Surgery Clinic, Mardin, Turkey 2Nusaybin State Hospital, Dermatology and Venereology, Mardin, Turkey *Corresponding author: Received Date: October 24, 2020 Published Date: November 03, 2020 Akif İşlek, Nusaybin State Hospital, Otolaryngology-Head & Neck Surgery Clinic, Mardin, Turkey. Abstract Treatment of earwax often involves the use of a wax softening agent (cerumenolytic) with or without antimicrobial agents to easily removing. Cerumenolytic agents used to remove and soften earwax areoil-based treatments, water-based treatments. Fixed drug eruption (FDE) is a well- defined, circular, hyperpigmented plaque that usually occurs on the trunk, hands mucosal surfaces, after a systemical application of drugs. In this report, a case with FDE developed after a cerumenolytic agent (hydrogen peroxide and boric acid in water). A definitive diagnosis was made with skin punch biopsy and FDE was treated with oral levocetirizine and topical mometasone. Introduction is a well-defined, circular, hyper pigmenting plaque that usually Cerumen production is a normal and protective process occurs on the genitals, lips, trunk, and hands and the diagnosis for the external ear canal (EAC), but impact of cerumen causes can be confirmed by histopathologic examination of a small punch symptoms such as hearing loss, itching, pain, tinnitus [1]. Cerumen biopsy specimen [5]. In this report, a case with FDE developed after impaction is defined as an accumulation of cerumen in the a cerumenolytic agent (hydrogen peroxide and boric acid in water) external ear [2]. -
United States Patent (10) Patent No.: US 8,969,514 B2 Shailubhai (45) Date of Patent: Mar
USOO896.9514B2 (12) United States Patent (10) Patent No.: US 8,969,514 B2 Shailubhai (45) Date of Patent: Mar. 3, 2015 (54) AGONISTS OF GUANYLATECYCLASE 5,879.656 A 3, 1999 Waldman USEFUL FOR THE TREATMENT OF 36; A 6. 3: Watts tal HYPERCHOLESTEROLEMIA, 6,060,037- W - A 5, 2000 Waldmlegand et al. ATHEROSCLEROSIS, CORONARY HEART 6,235,782 B1 5/2001 NEW et al. DISEASE, GALLSTONE, OBESITY AND 7,041,786 B2 * 5/2006 Shailubhai et al. ........... 530.317 OTHER CARDOVASCULAR DISEASES 2002fOO78683 A1 6/2002 Katayama et al. 2002/O12817.6 A1 9/2002 Forssmann et al. (75) Inventor: Kunwar Shailubhai, Audubon, PA (US) 2003,2002/0143015 OO73628 A1 10/20024, 2003 ShaubhaiFryburg et al. 2005, OO16244 A1 1/2005 H 11 (73) Assignee: Synergy Pharmaceuticals, Inc., New 2005, OO32684 A1 2/2005 Syer York, NY (US) 2005/0267.197 A1 12/2005 Berlin 2006, OO86653 A1 4, 2006 St. Germain (*) Notice: Subject to any disclaimer, the term of this 299;s: A. 299; NS et al. patent is extended or adjusted under 35 2008/0137318 A1 6/2008 Rangarajetal.O U.S.C. 154(b) by 742 days. 2008. O151257 A1 6/2008 Yasuda et al. 2012/O196797 A1 8, 2012 Currie et al. (21) Appl. No.: 12/630,654 FOREIGN PATENT DOCUMENTS (22) Filed: Dec. 3, 2009 DE 19744O27 4f1999 (65) Prior Publication Data WO WO-8805306 T 1988 WO WO99,26567 A1 6, 1999 US 2010/O152118A1 Jun. 17, 2010 WO WO-0 125266 A1 4, 2001 WO WO-02062369 A2 8, 2002 Related U.S. -
(12) Patent Application Publication (10) Pub. No.: US 2011/0158930 A1 Hirata Et Al
US 2011 O15893 OA1 (19) United States (12) Patent Application Publication (10) Pub. No.: US 2011/0158930 A1 Hirata et al. (43) Pub. Date: Jun. 30, 2011 (54) METHOD FOR TREATMENT OF RRTABLE Related U.S. Application Data BOWEL, SYNDROME (60) Provisional application No. 61/190.559, filed on Aug. 28, 2008. (75) Inventors: Takuya Hirata, Tokyo (JP); Toshiyuki Funatsu, Tokyo (JP); Publication Classification Yoshihiro Keto, Tokyo (JP); (51) Int. Cl. Shinobu Akuzawa, Tokyo (JP) A63L/78 (2006.01) C07D 403/06 (2006.01) (73) Assignee: ASTELLAS PHARMA INC., A6IPI/00 (2006.01) Tokyo (JP) A6IPL/T2 (2006.01) (52) U.S. Cl. ................................... 424/78.01: 548/302.7 (21) Appl. No.: 13/061,384 (57) ABSTRACT A method for treatment of a patient suffering from irritable (22) PCT Fled: Aug. 27, 2009 bowel syndrome with diarrhea or mixed irritable bowel syn drome, which comprises administering to the patient a thera (86) PCT NO.: PCT/UP2009/064904 peutically effective amount of ramosetron or a pharmaceuti cally acceptable salt thereof in combination with a S371 (c)(1), therapeutically effective amount of polycarbophil or a phar (2), (4) Date: Feb. 28, 2011 maceutically acceptable salt thereof. Patent Application Publication Jun. 30, 2011 Sheet 1 of 2 US 2011/O1589.30 A1 Fig.1 s 120 aw *e 100 aS$ 100 80 isd 80 v s 60 se sk sk 60 40 6 40 se g 20 20 - a k es O -- - - - , , , g- O W 0. 0.3 1 100 300 000 0.3 g/kg 300 mg/kg 0.3 g/kg + s S. -
Common Ear, Nose & Throat Problems
Common Ear, Nose & Throat Problems The information provided in this presentation is not intended to guide treatment or aid in making a diagnosis. Always consult a physician or nurse practitioner. Copyright 2002, 2014, Kevin T. Kavanagh All Rights Reserved www.entusa.com Normal Larynx Normal larynx in a 44 yr old non-smoker Go to http://www.entusa.com/normal_larynx.htm to View Video Copyright 2002, 2014, Kevin T. Kavanagh All Rights Reserved www.entusa.com Acute Laryngitis This video shows the function of the larynx in a 24 yr old patient with acute laryngitis. Talking was painful and she only talked in a faint whisper. Go to http://www.entusa.com/laryngitis.htm to View Video Copyright 2002, 2014, Kevin T. Kavanagh All Rights Reserved www.entusa.com Vocal Cord Paralysis This video shows the function of a larynx with a paralyzed left true vocal cord. The patient has lung cancer. She has a poorly compensated breathy voice which is difficult to understand. This patient had a 55 pack year history of smoking. Go to http://www.entusa.com/vocal_cord_paralysis_2.htm to View Video Copyright 2002, 2014, Kevin T. Kavanagh All Rights Reserved www.entusa.com Vocal Cord Polyp This video shows the function of a larynx with a vocal cord polyp on the right true vocal cord. This patient smoked one pack a day for 30 years. Go to http://www.entusa.com/larynx_polyp-9.htm to View Video Copyright 2002, 2014, Kevin T. Kavanagh All Rights Reserved www.entusa.com Laryngeal Cancer This video shows the function of a larynx with a large T1b Cancer on both true vocal cords and anterior commissure in 72 yr old male with a 150 pack year history of smoking. -
EAR, NOSE and OROPHARYNX Updated: October 2020
Derbyshire Medicines Management, Prescribing and Guidelines DERBYSHIRE PRIMARY CARE FORMULARY CHAPTER 12: EAR, NOSE AND OROPHARYNX Updated: October 2020 The following prescribing guidelines are relevant to the ENT chapter and can be found here: • Allergic Rhinitis in adults and adolescents over 12 years of age • Management of chronic rhinosinusitis with or without nasal polyps 12.1 DRUGS ACTING ON THE EAR 12.1.1 Otitis externa Investigation is not routinely recommended for the initial diagnosis of otitis externa. Group Drug Astringent/acidic Acetic acid 2% ear spray preparations Self-care: patients are advised to purchase this over the counter Gentamicin 0.3% ear/eye drops* Antibiotic preparations Ciprofloxacin 2mg/ml ear drops 0.25ml unit dose PF Betnesol-N ear/eye/ nose drops* Combined corticosteroid (Betamethasone 0.1% & neomycin 0.5%) and aminoglycoside Otomize ear spray* antibiotic preparations (Dexamethasone 0.1%, neomycin 0.5% & acetic acid 2%) Corticosteroid Prednisolone 0.5% ear/eye drops Lower potency preparations Betamethasone 0.1% ear/eye/ nose drops Higher potency Antifungal preparations Clotrimazole 1% solution 20ml (with dropper) * In view of reports of ototoxicity, manufacturers contra-indicate treatment with topical aminoglycosides in patients with a perforated tympanic membrane (eardrum) or patent grommet. 1. The following are GREY, not for first line empirical use, and should only be used when sensitivity is confirmed through swab results- • Hydrocortisone acetate 1%/gentamicin 0.3% ear drops • Flumetasone pivalate 0.02%/clioquinol 1% ear drops 2. How should I treat acute diffuse otitis externa? (CKS) • Remove or treat any precipitating or aggravating factors. • Prescribe or recommend a simple analgesic for symptomatic relief. -
10/15-Hour Medication Test Answers
Appendix 10/15-Hour Medication Test Answers Name _________________________________ Facility _________________________________ Part 1: Match the term or phrase on the right with the abbreviation or term on the left by placing the correct letter on the appropriate line. _____ 1. PRN (p) a. milligram _____ 2. ac (e) b. at bedtime _____ 3. stat (j) c. Medication Administration Record _____ 4. SL (k) d. over the counter _____ 5. MAR (c) e. before meals _____ 6. mg (a) f. tablespoonful _____ 7. pc (m) g. placed and affixed to the skin _____ 8. OTC (d) h. teaspoonful _____ 9. Subcutaneous (r) i. milliliter _____ 10. po (n) j. immediately _____ 11. qhs (b) k. sublingual _____ 12. tbsp (f) l. placed under the tongue _____ 13. transdermal (g) m. after meals _____ 14. ml (i) n. by mouth _____ 15. gm (o) o. gram _____ 16. QOD (q) p. as needed _____ 17. tsp (h) q. every other day _____ 18. sublingual (l) r. inject into the fat with a syringe Medication Administration – March 2021 10/15-Hour Training Course for Adult Care Homes 4 Appendix 10/15-Hour Medication Test Answers – Continued Part 2: Fill in the blank with the appropriate word or term. You may choose to use the word bank below. 19. A heart tablet taken by mouth and swallowed is an example of a medication taken by the oral route. 20. A medication that is inserted into the rectum is given using the rectal route. 21. A topical medication is applied directly to the skin surface. -
GENTAMICIN Eye/Ear Drops 0.3% W/V Gentamicin Sulphate Please
GENTAMICIN Eye/Ear Drops 0.3% w/v Gentamicin Sulphate Please read this leaflet carefully before you start using this medicine. Keep this leaflet. You may need to read it again. If you have further questions, please ask your doctor or pharmacist. This medicine has been prescribed for you personally and you should not pass it on to others. It may harm them, even if their symptoms are the same as yours. If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist. The medicine will be called Gentamicin in this leaflet. In this leaflet: 1. What Gentamicin is and what it is used for 2. Before you use Gentamicin 3. How to use Gentamicin 4. Possible side effects 5. How to store Gentamicin 6. Further information 1. WHAT GENTAMICIN IS AND WHAT IT IS USED FOR Gentamicin eye/ear Drops are a sterile, preserved, aqueous solution used as eye/ear drops. The active ingredient Gentamicin is an antibiotic used to kill bacteria which cause infection. It is used for the management of eye & ear infection. 2. BEFORE YOU USE GENTAMICIN Do not use if you are allergic to Gentamicin, any of the ingredients, or any other aminoglycoside antibiotics if you have a perforated ear drum if you suffer from myasthenia gravis and related conditions Before you use Gentamicin: Take special care with Gentamicin Avoid prolonged use The drops must not be used in the ear if the ear drum is damaged in any way. -
Therapeutic Class Overview Otic Fluoroquinolones
Therapeutic Class Overview Otic Fluoroquinolones Therapeutic Class • Overview/Summary: This review will focus on the otic fluoroquinolone antibiotics.1-4 Topical corticosteroids help to aid in the resolution of the inflammatory response accompanying bacterial infections.3,4 Fluoroquinolones are broad-spectrum antimicrobial agents that directly inhibit bacterial deoxyribonucleic acid (DNA) synthesis by blocking the actions of DNA gyrase and topoisomerase IV, which leads to bacterial cell death.5 The otic antibacterials are approved for the treatment of otitis externa and otitis media. Otitis externa (also known as swimmer’s ear) is an inflammatory condition of the external ear canal auditory canal or auricle, usually from infection. Common infectious pathogens include S. aureus, S. epidermidis and P. aeruginosa; however, several other gram-positive, gram-negative and anaerobic infections along with polymicrobic infections occur frequently.6 Topical antibacterials (alone or in combination with a corticosteroid) are very effective and systemic therapy is generally not required.7 Acute otitis media is an inflammatory condition of the middle ear with middle ear effusion and symptoms include otalgia, hearing loss and vertigo.8 Common pathogens in children include S. pneumoniae and H. influenzae (and M. catarrhalis in children).8,9 Oral antibacterials are generally the initial treatment option for children and adults; however, topical antibacterials with or without corticosteroids may be used in patients with perforated tympanic membranes, tympanostomy -
Standard Treatment Guidelines and Essential Drugs List
STANDARD TREATMENT GUIDELINES AND ESSENTIAL DRUGS LIST FOR THE MINISTRY OF HEALTH, TONGA- 2007. Standard Treatment Guidelines Tonga 2007 Standard Treatment Guidelines and Essential Drugs List: Ministry of Health. First Edition, 2007 Copyright © 2007, Ministry of Health, Tonga All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, scanned or transmitted in any form without the permission of the copyright owner. Ministry of Health PO Box 59 Nuku’alofa Tonga Phone: 676 23200 Fax: 676 24291 E-mail address: [email protected] Editors: Siale ‘Akau’ola & Siutaka Siua Cover design by: Owen Towle Formatted by: T. Nauna Paongo Printed by: Taulua Press STG 2 Ministry of Health Standard Treatment Guidelines Tonga 2007 TABLE OF CONTENTS 1. FOREWORD: 13 2. ABBREVIATIONS AND ACRONYMS: 14 3. ACKNOWLEDGEMENTS: 17 4. INTRODUCTION: 19 5. ACCIDENT AND EMERGENCY (A&E): 21 5.1. General Approach to A&E 21 5.2. Cardiac Arrest 26 5.3. Other Life Threatening Emergencies 30 5.4. Infectious Diseases 52 5.5. Severe Hypertension 58 5.6. Abdominal Pain 59 5.7. Surgical Problems 60 5.8. Red Eye 66 5.9. Dog Bite 67 6. CARDIOVASCULAR CONDITIONS. 68 6.1. Heart Failure 68 6.2. Myocardial Infarction 72 6.3. Cardiogenic Shock 77 6.4. Acute Coronary Syndrome (ACS) 79 6.5. Cardiac Arrythmias 80 6.6. Cardiac Arrest 87 6.7. Hypertension 89 6.8. Aortic Dissection 93 6.9. Bacterial Endocarditis 96 6.10. Infective Endocarditis Prophylaxis 97 7. CENTRAL NERVOUS SYSTEM (CNS) CONDITIONS 104 7.1 Headache 104 STG 3 Ministry of Health Standard Treatment Guidelines Tonga 2007 7.2 Seizures 107 7.3 Meningitis 108 7.4 Stroke 108 7.5 Involuntary Movement Disorders 110 7.6 Epilepsy 111 8 COMMON EAR, NOSE AND THROAT PROBLEMS. -
Texas Medication Aides Basic Course Curriculum for Nursing Facilities and Related Institutions
Texas Medication Aides Basic course curriculum for Nursing Facilities and related institutions Effective Date: January 2017 Texas Health and Human Services Commisson (HHSC) Medication Aide Program, E‐416 P.O. Box 14930, Austin, Texas 78714‐9030 Communicate before you medicate! Helping people make the best of medications REVISED JUNE 2016 | Texas Health and Human Services Commisson (HHSC) HHSC Licensing and Credentialing TEXAS MEDICATION AIDE AND BASIC COURSE CURRICULUM 100‐hour curriculum Acknowledgements We would like to extend a very special thank you to the following people who worked many hours in revising and updating this curriculum. Your cooperation and dedication is appreciated. Darren Christian, R.N., Texas Health and Human Services Commisson, Elizabeth Demps, Texas Health and Human Services Commisson, Katherine Hafner, B.S, R.Ph, Fellow in the American Society of Consultant Pharmacists, Kim Lammons Texas Health and Human Services Commisson, Debi Majo, BSN R.N., TMF Health Quality Institute, Elizabeth McManamy, R.Ph, Texas Health and Human Services Commisson, Joyce Meredith, Texas Health and Human Services Commisson, Carolyn Reese, MSN, R.N., Blinn College, Brenda Renfro‐King, R.N., McLennan Community College, Jacqueline Smith, Texas Health and Human Services Commisson, Camden Frost, Texas Health and Human Services Commisson, Sean Steele, Texas Department on Aging and Disability Services, Sunny Stout, R.N., Senior Care Centers, Mavon Tidwell, R.N., Marble Falls High School, Kingsland Hills Care Center, Anne Trejo, Texas Health and Human Services Commisson. © 2016 Texas Health and Human Services Commisson (formerly Texas Department of Human Services) TEXAS HEALTH AND HUMAN SERVICES COMMISSION (HHSC) 1 TEXAS MEDICATION AIDE AND BASIC COURSE CURRICULUM 100‐hour curriculum Table of Contents: Medication Aide and basic course curriculum Unit I.