12Th European Breast Cancer Conference (EBCC-12) 32Nd EORTC-NCI-AACR Sympos
Total Page:16
File Type:pdf, Size:1020Kb
127 127 Volume 138S1,138S2 1273S1, OctoberOctober March 20202020 2020 ISSN 0959-8049 Volume 127, March 2020 ISSN 0959-8049 EUROPEAN JOURNAL OF CANCER JOURNAL OFEUROPEAN CANCER EUROPEAN JOURNAL OF CANCER Pure J The world’s leading EEUROPEANJ JOURNAL OF CANCER EEUROPEAN JOURNALC OF CANCER research information Vol. management system Vol. 127 (2020) 1–250 127 THE 12TH EUROPEAN BREAST CANCER CONFERENCE (EBCC-12) S1 (2 12th32nd European EORTC-NCI-AACR Breast Cancer Symposium Conference on IN (EMolecular THISBCC ISSUE-12) Targets and Cancer Therapeutics 018) 1–154 182–3–2 0October March 20202020 ACCELERATE and European Medicines Agency VirtualBarcelona, Conference Spain Helping universities Paediatric Strategy Forum24–25 for Octobermedicinal product 2020 development of checkpointVirtual inhibitors Conference for use in and research combination therapy ABSTRACTin paediatricABSTRACTS patients BOOK institutions improve Is it time to redefine ABSTRACTcisplatin ineligibility BOOK in metastatic urothelial cancer? their performance Tumour infiltrating lymphocytes and correlation with up-to-date data with response to intensified platinum-based and analytics chemotherapy in BRCA -like tumours elsevier.com/research-intelligence THE OFFICIAL JOURNAL OF THE OFFICIAL JOURNAL OF ELSEVIER ELSEVIER 3906_Cover.indd All Pages 23-Feb-18 8:43:31 PM EJC_v127_iC_COVER.indd 1 12-02-2020 17:31:31 Volume 138S268, Supplement 1 OctoberDecember 2020 2016 ,661 European Journal of Cancer th 32nd EORTC-NCI-AACR28 EORTC – NCI – Symposium AACR Symposium on Molecular on MolecularTargets Targets and Cancer and Cancer Therapeutics Therapeutics Munich, Germany,24–25 29 OctoberNovember 2020 – 2 December 2016 Virtual Conference Abstract Book Publication of this supplement was supported by the EORTC Amsterdam • Boston • London • New York • Oxford • Paris • Philadelphia • San Diego • St Louis European Journal of Cancer Editor-in-Chief: Alexander M.M. Eggermont Princess Máxima Center for Pediatric Oncology Utrecht, Netherlands Editors: Preclinical Cancer Research: Ulrich Keilholz, Berlin, Germany Epidemiology and Prevention: Valery E.P.P. Lemmens, Utrecht, The Netherlands Tumour Immunotherapy: Aure ´lien Marabelle, Villejuif, France Breast Cancer: Giuseppe Curigliano, Milan, Italy Suzette Delaloge, Villejuif, France Gastrointestinal Cancers: Volker Heinemann, Munich, Germany Michel Ducreux, Villejuif, France Genitourinary Cancers: Karim Fizazi, Villejuif, France Head and Neck Cancer: J.P. Machiels, Brussels, Belgium Hemato-Oncology: Roch Houot, Rennes, France Lung Cancer: Martin Schuler, Essen, Germany Gynaecological Cancers: Ignace Vergote, Leuven, Belgium Endocrine, Sarcomas and Other Rare Tumours: Stefan Sleijfer, Rotterdam, The Netherlands Melanoma: Dirk Schadendorf, Essen, Germany Neuro-Oncology: Martin van den Bent, Rotterdam, The Netherlands Paediatric Oncology: Rob Pieters, Utrecht, The Netherlands Founding Editor: Henri Tagnon Past Editors: Michael Peckham, London, UK; Hans-Jo¨rg Senn, St Gallen, Switzerland; John Smyth, Edinburgh, UK Editorial Offi ce: Elsevier, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, UK Tel: +44 (0) 1865 843590, Email: [email protected] EDITORIAL BOARD CLINICAL ONCOLOGY R. Baird (UK) J.C. Horiot (Switzerland) D. Nam (Korea) N. Brünner (Denmark) D. Jäger (Germany) J. Perry (Canada) R. Califano (UK) A. Katz (Brazil) J. Ringash (Canada) E. Calvo (Spain) C. Le Tourneau (France) A. Rody (Germany) F. Cardoso (Portugal) Y. Loriot (France) M. Schmidinger (Austria) S. Sleijfer (The Netherlands) E. de Vries (The Netherlands) C-C. Lin (Taiwan) S. Stacchiotti (Italy) A. Dicker (USA) P. Lorigan (UK) C. Sternberg (Italy) R. Dummer (Switzerland) C. Massard (France) A. van Akkooi (The Netherlands) S. Erridge (UK) K. McDonald (Australia) E. Van Cutsem (Belgium) H. Gelderblom (The Netherlands) F. Meunier (Belgium) G. Velikova (UK) B. Geoerger (France) A. Miller (Canada) E. Winquist (Canada) B. Hasan (Belgium) T. Mok (Hong Kong) T. Yap (UK) BASIC SCIENCE, PRECLINICAL AND TRANSLATIONAL RESEARCH P. Allavena (Italy) J.M. Irish (USA) S. Singh (Canada) J. Anderson (UK) H.E.K. Kohrt (USA) J. Stagg (Canada) M. Broggini (Italy) J. Lunec (UK) C. Catapano (Switzerland) A.M. Müller (USA) A. Virós (UK) C. Caux (France) D. Olive (France) B. Weigelt (USA) M. Esteller (Spain) A.G. Papavassiliou (Greece) E. Garattini (Italy) V. Rotter (Israel) T. Yap (UK) R. Giavazzi (Italy) V. Sanz-Moreno (UK) N. Zaffaroni (Italy) EPIDEMIOLOGY AND PREVENTION B. Armstrong (Australia) D. Forman (France) P. Peeters (The Netherlands) P. Autier (France) A. Green (Australia) S. Sanjose (Spain) V. Bataille (UK) K. Hemminki (Germany) M.K. Schmidt (The Netherlands) J.M. Borras (Spain) C. Johansen (Denmark) I. Soerjomataram (France) C. Bosetti (Italy) L.A. Kiemeney (The Netherlands) H. Storm (Denmark) H. Brenner (Germany) I. Lansdorp-Vogelaar (The Netherlands) L.V. van de Poll-Franse (The Netherlands) L.E.M. Duijm (The Netherlands) E. Lynge (Denmark) H.M. Verkooijen (The Netherlands) J. Faivre (France) M. Maynadie´ (France) E. de Vries (The Netherlands) S. Franceschi (France) H. Møller (UK) R. Zanetti (Italy) PAEDIATRIC ONCOLOGY C. Bergeron (France) G. Chantada (Argentina) L. Sung (Canada) A. Biondi (Italy) F. Doz (France) M. van den Heuvel-Eibrink (The Netherlands) E. Bouffet (Canada) A. Ferrari (Italy) M. van Noesel (The Netherlands) M. Cairo (USA) M.A. Grootenhuis (The Netherlands) H. Caron (The Netherlands) K. Pritchard-Jones (UK) European Journal of Cancer Aims and Scope The European Journal of Cancer (EJC) integrates preclinical, translational, and clinical research in cancer, from epidemiology, carcinogenesis and biology through to innovations in cancer treatment and patient care. The journal publishes original research, reviews, previews, editorial comments and correspondence. The EJC is the offi cial journal of the European Organisation for Research and Treatment of Cancer (EORTC) and the European Society of Breast Cancer Specialists (EUSOMA). For a full and complete Guide for Authors, please go to http://www.ejcancer.com Advertising information. Advertising orders and inquiries can be sent to: USA, Canada and South America: Bill Hipple Advertising Department, Elsevier Inc., 230 Park Avenue, Suite 800, New York, NY 10169-0901, USA; phone: (+1) 646-671-0385; fax: (+1) (212) 633 3820; e-mail: [email protected]. Europe and ROW: Advertising Sales: Elsevier Pharma Solutions; 125 London Wall, London, EC2Y 5AS, UK; Tel.: +48 500 259 970; fax: +44 (0) 20 7424 4433; e-mail: [email protected]. Publication information: European Journal of Cancer (ISSN 0959-8049). For 2020, volumes 124–141 (18 issues) are scheduled for publication. Subscription prices are available upon request from the Publisher or from the Elsevier Customer Service Department nearest you or from this journal’s website (http://www.elsevier.com/locate/ ejca). Further information is available on this journal and other Elsevier products through Elsevier’s website (http://www.elsevier.com). Subscriptions are accepted on a prepaid basis only and are entered on a calendar year basis. Issues are sent by standard mail (surface within Europe, air delivery outside Europe). Priority rates are available upon request. Claims for missing issues should be made within six months of the date of despatch. Orders, claims, and journal inquiries: Please visit our Support Hub page https://service.elsevier.com for assistance. Author inquiries You can track your submitted article at http://www.elsevier.com/track-submission. You can track your accepted article at http://www.elsevier.com/trackarticle. You are also welcome to contact Customer Support via http://support.elsevier.com. Language (usage and editing services). Please write your text in good English (American or British usage is accepted, but not a mixture of these). Authors who feel their English language manuscript may require editing to eliminate possible grammatical or spelling errors and to conform to correct scientifi c English may wish to use the English Language Editing service available from Elsevier’s WebShop http://webshop.elsevier.com/languageediting/ or visit our customer support site http://support.elsevier.com for more information. Illustration services Elsevier’s WebShop (http://webshop.elsevier.com/illustrationservices) offers Illustration Services to authors preparing to submit a manuscript but concerned about the quality of the images accompanying their article. Elsevier’s expert illustrators can produce scientifi c, technical and medical-style images, as well as a full range of charts, tables and graphs. Image ‘polishing’ is also available, where our illustrators take your image(s) and improve them to a professional standard. Please visit the website to fi nd out more. Funding body agreements and policies. Elsevier has established agreements and developed policies to allow authors whose articles appear in journals published by Elsevier, to comply with potential manuscript archiving requirements as specifi ed as conditions of their grant awards. To learn more about existing agreements and policies please visit http:// www.elsevier.com/fundingbodies. © 2020 Elsevier Ltd. All rights reserved This journal and the individual contributions contained in it are protected under copyright, and the following terms and conditions apply to their use in addition to the terms of any Creative Commons or other user license that has been applied by the publisher to an individual article: Photocopying. Single photocopies of single articles may be made for personal use as allowed