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PHYSIOLOGY NEWS summer 2009 I number 75 Calcium signalling insights from Sir Michael Berridge Physiology 2009 – back at UCD after an 18 year break Conference networking leads to post-doc position on a Japanese tropical island PowerLab : buy or rent Easy to use, easy to acquire PowerLab® Teaching Systems with LabTutor® and LabChart® soft ware have set the benchmarks in quality, ease-of-use, safety and fl exibility for over 20 years. Now, we’re proud to introduce another industry fi rst...the option to either buy or rent this powerful technology! Th e choice of purchase or rental options makes it even easier to get the world’s leading data acquisition system for Buy or Rent life science education. Our new Smart Rent Option off ers brand-new systems, low entry cost and free experiment soft ware upgrades. Talk to us to fi nd out more. 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Tel: 01865 891 623 Email: [email protected] Web: www.adinstruments.com/buy_rent EQUIPMENT CERTIFIED FOR HUMAN CONNECTION UK • GERMANY • USA • BRAZIL • CHILE • INDIA • JAPAN • CHINA • MALAYSIA • NEW ZEALAND • AUSTRALIA CELEBRATING OVER 20 YEARS OF INNOVATIONS ADI_InstStudent_UK_PhysioNews.indd 1 15/5/09 2:32:20 PM PHYSIOLOGY NEWS Editorial 3 Meetings The Society’s dog. ‘Rudolf Magnus 36th IUPS International Congress Yasushi Miyashita 4 gave me to Charles Sherrington, who Welcome to University College Dublin Katherine Howell, gave me to Henry Dale, who gave me James Jones 5 to The Physiological Society in October Physiological signalling: from genes to function Trevor Wardill 6 1942’ Epithelial form, function and environment Andreas Werner, Mike Gray 8 Published quarterly by The Physiological Society The ageing musculoskeletal system Carolyn Greig, Steve Contributions and queries Harridge, Di Newham, Sam Lucas 9 Senior Production Editor 22 years in the life of... Jill Berriman ... The Society’s Publications Office Linda Rimmer, Jill Berriman 10 Editorial Administrator Letter from Japan Ed Sexton Conference networking materialises into dream postdoctoral The Physiological Society Publications Office position on sub-tropical island Fiona Randall 11 PO Box 502, Cambridge CB1 0AL, UK Features Tel: +44 (0)1223 400180 When fatiguing cycling muscles complain, the brain Fax: +44 (0)1223 246858 insightfully responds! Markus Amann, Jerome Dempsey 13 Email: [email protected] Muscles under stress Silvestro Roatta, Dario Farina 15 Website: www.physoc.org/magazine Novel player in insulin resistance: focal adhesion kinase Bharti Bisht, K Srinivasan, Chinmoy Dey 17 Magazine Editorial Board Is brain carbohydrate consumption driven by adrenaline? Editor Thomas Seifert 20 Austin Elliott Parathyroid hormone-related protein (PTHrP): a modulator of University of Manchester, Manchester, UK fetal growth and development Mark Dilworth, Jocelyn Glazier 22 Members Calcium: it’s not just for bones! Brenda Finney, William Angus Brown Wilkinson, Paul Kemp, Daniela Riccardi 25 University of Nottingham, Nottingham, UK Where do we look while sleeping? Javier Márquez-Ruiz, Miguel Escudero 28 Patricia de Winter The peri-conceptional origins of the life-long physiological University College London, London, UK consequences of being a twin Frank Bloomfield 31 Sarah Hall Interview Cardiff University, Cardiff, UK Thinking the thoughts of a cell Michael Berridge, Austin Elliott 34 Munir Hussain Reports University of Bradford, Bradford, UK Tomorrow’s women, tomorrow’s world Valerie Gladwell 37 John Lee Profile: Emily avies,D participant on the BPS/Physiological Rotherham General Hospital, Rotherham, UK Society in vivo short course Judith Hall 38 Professor Tilli Tansey Inaugral Lecture John Berriman 39 Thelma Lovick Forty metre man leaves brain behind in Bristol Anne Cooke 40 University of Birmingham, Birmingham, UK The annual meeting of the Society for Gynaecologic Foreign Correspondents Investigation Jane Cleal 41 John Hanrahan Voice of Young Science Media workshop Ellen Forty 42 McGill University, Montreal, Canada 59th Annual Conference of the British Microcirculation John Morley Society 2009 Neena Kallia 43 University of Western Sydney, NSW, Australia Memorable physiologists In the footsteps of giants Patricia de Winter 44 Fiona Randall Unbelievable! 45 Okinawa Institute of Science and Technology, Okinawa, Japan Letter to the Editor 46 Book reviews 47 © 2009 The Physiological Society From the archives Austin Elliott 51 ISSN 1476-7996 Biosciences Federation–Society of Biology 52 The Physiological Society is registered in England as a Society update Mike Collis 53 company limited by guarantee: No 323575. Education Registered office: PO Box 11319, London WC1X 8WQ CaSE Liz Bell 54 Registered Charity: No 211585. The new invisible college: how globilisation is changing the Printed by The Lavenham Press Ltd landscape for scientific collaboration Liz Bell 55 Membership activities Irrum Magre 56 Exciting pupils about biology Fiona Wyllie 56 The Discovery Zone at Leeds Sue Deuchars 58 Hot topics meeting in pharmacology and physiology 2009 Liz Bell 59 Do we need more multiskilled scientists and engineers to manage economic recovery and change Liz Bell 59 The Society’s journals The Journal of Physiology 60 Experimental Physiology 61 New journal websites Liam McKay 62 Obituaries Cover image adapted from a model of membrane inositides (see Interview, p. 34) (with permission of The Hans Meves Hans-Christoph Lüttgau, Knox Chandler 63 Advancing the science of life Babraham Institute: www.babraham.ac.uk/inositide) Noticeboard 64 PHYSIOLOGY NEWSSearch term PubMed hits Biology 770 (923) Guidelines for contributors ChemistryAction 1639 points (380) In this issue These guidelines are intended to assist PhysicsGrants 346 (236) authors in writing their contributions and Welcome to the Summer 2009 The Society offers funding through Physiology News Biochemistry 56 (142) to reduce the subsequent editing process. the following grant schemes: The Editorial Board of Physiology News Summer is traditionally conference MedicineTravel Grants, Non-Society122 (101) tries to ensure that all articles are written season, and in keeping with that this MolecularSymposia biology Grants, 212Outreach Grants, in a journalistic style so that they will Physiology News carries a bumper International Teaching and Research have an immediate interest value for a crop of conference previews and Pharmacology 516 (31) wide readership and will be readable and Grants and the Vacation Studentship reports (I think I counted 5 of each). Physiology 1706 (272) comprehensible to non-experts. Scientific and Departmental Seminar articles should give a good overview of I am also pleased to say this is a large SystemsSchemes. biology For full 57information, a field rather than focus entirely on the issue (64 pages), so it should prove ‘Molecular’please visit: 1337 authors’ own research. excellent for reading in airports, in http://www.physoc.org/grants Format of articles train stations, and in idle conference The main message or question posed moments – if you have any. Membership applications should be introduced in the first paragraph. The background for the topic The scientific content includes Applications for membership to The should then be established, leading up to muscle being stressed and fatigued Physiological Society are considered the final conclusion. (pp. 13–16) – I dare say a bit like on a rolling basis, and a decision is Length of articles most of us feel. We also have brains, normally made within 15 working This will be determined by the subject calcium, being born, growing and days. For full information, please matter and agreed with the Senior sleeping represented in the scientific visit: Publications Executive. features – so pretty much all aspects http://www.physoc.org/membership Submission of articles of life are represented in this issue. Authors should submit articles as a Word Is your membership information document attached to an email. Engagement in the broadest sense Illustrations should be sent as separate is likely to prove an increasing part correct? attachments (see below) and not of all our work in the years to come. Please check and update your embedded in the text. I am pleased to say we have several details at www.physoc.org, under Illustrations and authors’ photographs features with an engagement or ‘My Physoc Profile’. Authors are encouraged to submit outreach theme (see e.g. pp. 55–58), diagrams, drawings, photographs or other artwork with their articles, and a as well as an editorial asking all photograph of the author(s) should physiologists – you – to ‘do your bit’ Physiology News accompany submissions. Illustrations for physiology. and photographs may be colour or black Deadlines and white, and preferably TIFF, JPEG, And finally, on p. 10 we say our final Letters and articles and all other PNG, PDF or AI files with a minimum goodbye to our recently retired contributions for inclusion in the resolution of 300 dpi. Executive Editor, as