C al & ellu ic la n r li Im C m f u Journal of o n l o a l n o r Davtyan et al., J Clin Cell Immunol 2014, 5:2 g u y o J DOI: 10.4172/2155-9899.1000196 ISSN: 2155-9899 Clinical & Cellular Immunology Research Article Open Access Diminished IL-10 production is Associated with Impaired Versatility of Monocytes in Familial Mediterranean Fever Tigran K. Davtyan1*, Gagik S. Hakobyan2, Samvel A. Avetisyan3, Anna G. Sukiasyan4 and Yuri T. Aleksanyan4 1Laboratory of Immunology and Virology, "Armenicum" Research Centre, CJSC Armenicum, 37 Nalbandyan St., Yerevan, Republic of Armenia 2Department of Internal Medicine, Yerevan State Medical University, Koryun 2 St., Yerevan, Republic of Armenia 3Department of Pathophysiology; Yerevan State Medical University, Koryun 2 St., Yerevan, Republic of Armenia 4Laboratory of Epidemiology and Immunology, Institute of Epidemiology, Virology and Medical Parasitology, Ministry of Health RA, Yerevan, Armenia *Corresponding author: Dr. Tigran K. Davtyan, PhD, ScD, Analytical Laboratory Branch, Scientific Centre of Drug and Medical Technology Expertise JSC, Armenia, Tel: +374 10 23-72-61; Fax: +374 10 28-07-33; E-mail:
[email protected] Received date: Jan 15, 2014, Accepted date: Mar 10, 2014, Published date: Mar 17, 2014 Copyright: © 2014 Davtyan TK, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Abstract Purpose: The nature of the heightened endotoxin sensitivity state observed in Familial Mediterranean Fever (FMF) at present remains unknown.