The American Journal of

PATHOLOGY

Official Publication of the American Association ofPathologists

Editor-in-Chief Editorial Board Nelson Fausto Abul K. Abbas Ricardo V. Lloyd Brown University H. Clarke Anderson James L. Madara Dorothy F. Bainton Glenn Merlino Associate Editors Hector Battifora Alfred F. Michael Jeffrey Cossman Frederick Miller Sandra H. Bigner Riccardo Dalla-Favera George F. Murphy Duke University Dennis W. Dickson Brian J. Nickoloff Francis V. Chisari Robert E. Fechner Paul K. Pattengale Research Institute Victor J. Ferrans George Perry Scripps Isaiah J. Fidler R. Neal Pinckard Stanley R. Hamilton Michael A. Gimbrone, Jr. Jordan S. Pober Johns Hopkins University James E. Goldman Juan Rosai Nicholas K. Gonatas Russell Ross Agnes B. Kane Nancy L. Harris Eric P. Sandgren Brown University Aubrey J. Hough, Jr. Gary E. Striker Steven L. Kunkel Peter M. Howley Thomas W. Tillack Univers,ity of Michigan Philip M. lannaccone Manjeri A. Venkatachalam Harriet Isom Peter A. Ward Joseph A. Madri Elaine S. Jaffe Roger A. Warnke Ya/e University Yashpal S. Kanwar Lawrence M. Weiss Daniel M. Knowles James G. White George M. Martin Charles Kuhn Mark R. Wick University of Washington Paul E. Lacy Peter D. Yurchenco Jeffrey L. Sklar Lance A. Liotta Dorothea Zucker-Franklin Harvard University Managing Editor Marcia M. Robinson

The AmericanJounal ofPatbology (ISSN 0002-9440) is published monthly by the American Association of Pathologists at J. B. Lippincott Co., 12107 Insurance Way, Hagerstown, MD 21740. Business offices are located at 227 East Washington Square, Philadelphia, PA 19106. Printed in the U.S.A. Copyright C 1992 by the American Association of Pathologists. All rights reserved. Second class postage paid at Hagerstown, MD, and at additional mailing offices. Annual subscription rates: U.S.A.: $160.00 individual; S230.00 institution; 590.00 resident/student. Single issue, 526.00. All other countries (except Japan, India, Nepal, Bangladesh, and Sri Lanka), S230.00 individual; 5310.00 institution. 5155.00 Canadian resident/student. Rates for airmail delivery available upon request. Japan: 66,300 yen individual; 84,200 yen institution (includes airmall postage). Copies will be replaced without charge if the publisher receives a request within 60 days of the mailing date in the U.S.A. or within 5 months in all other countries. Subscription information, orders, or changes of address (except Japan, India, Nepal, Bangladesh, and Sri Lanka): 12107 Insurance Way, Suite 114, Hagerstown, MD 21740, or call 1-800-638-3030 (in Maryland, call collect: 301-714-2300). In Japan, contact USACO Corporation, 13- 12 Shimbashi 1-chome, Minato-ku, Tokyo, 105 Japan. In India, Nepal, Bangladesh, and Sri Lanka, contact Universal Subscription Agency Pvt. Ltd., 101-102 Community-Centre (F.F.) Saket, New Delhi-l 10017, India. POSTMASTER: send address changes to The American Journal of Pathology, P.O. Box 1550, Hagerstown, MD 21740. Advertising inquiries: Jennifer Bass, J. B. Lippincott Co., East Washington Square, Philadelphia, PA 19106, or call 215-238-4283. Copyright information: Copyright questions should be addressed to The Managing Editor, 9650 Rockville Pike, Bethesda, MD 20814-3993 (301-571-0107). Authorization to photocopy items for internal or personal use or the internal or personal use of specific clients is granted by the American Association of Pathologists to libraries and other users registered with the Copyright Clearance Center (CCC) Transactional Re- porting Service, provided that the base fee of 500.80 per copy, plus $00.05 per page is paid directly to CCC, 21 Congress Street, Salem, MA 01970. 0002-9440/92 500.80 + 500.05. Manuscript submission: Mail five copies of the manuscript and four sets of figures to: Nelson Fausto, M.D., The American Journal of Pathol- ogy, 9650 Rockville Pike, Bethesda, MD 20814-3993. Information for Authors may be obtained from the same address. 1520 Huffnagle and Lipscomb AJP December 1992, Vol. 141, No. 6

10. Balmes JR, Hawkins JG: Pulmonary cryptococcosis. Semin 13. Wasser L, Talavera W: Pulmonary cryptococcosis in AIDS. Respir Med 1987, 9:180-186 Chest 1987, 92:692-695 11. Cameron ML, Bartlett JA, Gallis HA, Waskin HA: Manifesta- 14. Huffnagle GB, Yates JL, Lipscomb MF: T cell-mediated im- tions of pulmonary cryptococcosis in patients with acquired munity in the lung: A Cryptococcus neoformans pulmonary immunodeficiency syndrome. Rev Infect Dis 1991, 13:64- infection model using SCID and athymic nude mice. Infect 67 Immun 1991, 59:1423-1433 12. Kerkering TM, Duma RJ, Shadomy S: The evolution of pul- monary cryptococcosis: Clinical implications from a study of 15. Lim TS, Murphy JW, Cauley LK: Host-etiological agent in- 41 patients with and without compromising host factors. Ann teractions in intranasally and intraperitoneally induced cryp- Intern Med 1981, 94:611-616 tococcosis in mice. Infect Immun 1980, 29:633-641

STATEMENT OF OWNERSHIP, MANAGEMENT AND CIRCULATION (Act of August 2,1970: Section 3685, Title 39 United States Code) Date of Filing-October 1, 1992. Title of Publication-American Journal of Pathology; Frequency of Issue-Monthly; Annual Subscription Price-$160.00; Location of Known Office of Publication-100 Insurance Way, Suite 114, Hagerstown, MD 21740; Location of Headquarters or General Business Offices of the Publisher-J. B. Lip- pincott Company, East Washington Square, Philadelphia, PA 19106; Publisher-J. B. Lippincott Company, 227 East Washington Square, Philadelphia, PA 19106; Editor-Nelson Fausto, M.D., Department of Pathology and Laboratory Medicine, Division of Biology, Brown University, Providence, RI 02912; Managing Editor-Marcia Robinson, American Association of Pathologists, 9650 Rockville Pike, Bethesda, MD 20014; Owner-American Association of Pathologists, 9650 Rockville Pike, Bethesda, MD 20014; Known Bondholders, Mortgagees, and other security holders owning or holding 1 percent or more of total amount of bonds, mortgages, or other securities-Wolters Kluwer, U.S. Corporation, 1185 Avenue of the Americas, 37th Floor, New York, NY 10036. A. Total no. copies printed (net press run), average 5158, actual 5000; B. Paid circulation 1. Sales through dealers and carriers, street vendors and counter sales, average none, actual none; 2. Mail subscriptions, average 4625, actual 4719; C. Total paid circulation, average 4625, actual 4719; D. Free distribution by mail, carrier or other means. Samples complimentary, and other free copies, average 107, actual 125; E. Total distribution (sum of C and D), average 4732, actual 4844; F. Copies not distributed 1. Office use, leftover, unac- counted, spoiled after printing, average 426, actual 156. Returns from news agents, none; G. Total (sum ofE & F-should equal net press runs shown in A), average 5158, actual 5000. I certify that the statements made by me above are correct and complete. J. W. Lippincott, Vice President. Index of Subjects

Volume 141, 1992

Actin and electron microscopy of angiopathy in Alzhei- mRNA abundance in heart affected by anthracy- mer's disease, 249 clines, 1187 identification of proteins in amyloid deposits in Adhesion molecules nerves, 217 on endothelium in atherosclerosis, 1427 P2-microglobulin amyloid fibril synthesis in cell cul- regulated expression of VCAM-1 in melanoma, tures, 241 1323 Anemia in thymic B-cell lymphoma, 729 myocyte changes in, 227 VCAM-1 in AIDS encephalitis, 1021 Angiotensin 11 Aging and tenascin expression in vascular smooth mus- amyloidosis in, 767 cle cells, 377 AIDS Animal models of human disease and Epstein-Barr virus in CNS lymphoma, 441 non-insulin-dependent human diabetes, 761 and VCAM-1 in encephalitis, 1021 pulmonary cryptococcosis, 1517 Albumin Anthracyclines expression in hepatic hyperplasia and preneopla- and actin mRNA abundance in heart, 1187 sia, 623 Apolipoprotein Al Alcoholism role in amyloidosis, 1013 liver disease in, 69 Apoptosis Alpha-fetoprotein transfer between nuclei, 1471 expression in hepatic hyperplasia and preneopla- Arthritis sia, 623 and serum amyloid A transcription in synovium, Alzheimer's disease 525 and Alz-50 immunoreactivity in brain, 1459 Atherosclerosis amyloid angiopathy in, 249 adhesion molecules on endothelium in, 1427 ,-amyloid precursor protein in nucleus basalis, extracellular and cellular lipid deposits in, 925 357 and fatty streaklike lesions induced in culture amyloidosis in, 767 model of arterial intima, 1435 genesis of senile plaque in, 1151 macrophage differentiation in, 161 immunoelectron microscopy of neurofibrillary tan- macrophage scavenger receptors in, 591 gles in, 343 in transplanted organs, 1139 thrombospondin in, 783 Amyloid A transcription in arthritic synovium, 525 Basal cells Amyloid P repair mechanisms in airway epithelium, 753 in fibrils of fibrillary glomerulopathy, 409 Basophils serum levels affecting amyloid deposition, 451 analysis of release reactions in, 1309 P-Amyloid precursor protein Bauhinia purpurea in nucleus basalis in Alzheimer's disease, 357 as marker for Reed-Sternberg cells, 19 ,3-Amyloid protein bcl-2 gene in inclusion-body myositis, 31 lack of translocation in Hodgkin's disease, 193 Amyloidosis rearrangements in reactive lymphoid tissue, 291 in aging and Alzheimer's disease, 767 Bladder apolipoprotein Al in, 1013 cystitis in Lyme disease in mice, 1173

1521 1522 Index of Subjects AJP December 1992, Vol. 141, No. 6

Bleomycin CD5 monoclonal antibodies stimulating alveolar macrophages, 965 peripheral blood dendritic cell reactivity with, 789 Blood-brain barrier CD31 permeability in experimental brain metastases, in transmigrating lymphocytes, 843 1115 Cervix uteri Bone keratin expression in cancer, 497 giant cell tumors producing matrix metalloprotein- localization of retinoid-binding proteins in, 973 ases, 61 1 tenascin in koilocytotic lesions, 907 Brain Collagen abnormal prion protein distribution in, 271 affecting mesangial cells, 429 abscesses in rats, 1299 Collagenase amyloid angiopathy in Alzheimer's disease, 249 distribution in colorectal neoplasia, 389 amyloid deposits in aging and Alzheimer's dis- interstitial expression in oral carcinoma, 301 ease, 767 mesangial, in glomerulonephritis, 85 ,B-amyloid precursor protein in nucleus basalis, Colorectal tumors 357 distribution of collagenase and its inhibitor in, 389 blood-brain barrier permeability in experimental laminin receptor mRNA in, 1073 brain metastases, 1 1 15 nuclear morphology and genetics in, 797 (CA)n repeats for loss of heterozygosity assay in Coxsackievirus Infection tumors, 777 myocarditis in, heparin affecting, 203 Epstein-Barr virus in AIDS-related CNS lymphoma, Cryptococcosis 441 pulmonary, animal model of, 1517 genesis of senile plaque, 1151 Cyclin. See Proliferating cell nuclear antigen (PCNA) heat shock protein 72 in meningitis, 53 Cystitis immunoelectron microscopy of neurofibrillary tan- in Lyme disease in mice, 1173 gles, 343 Cytokeratins a2-macroglobulin receptor in, 37 suprabasal CK19 in oral cavity dysplasia, 817 neuronal changes in photodynamic therapy, 989 in uveal melanoma, 169 synaptophysin expression in tumors induced by Cytokines ethyl nitrosourea, 1037 alterations in metastatic cancer cells, 519 thrombospondin in Alzheimer's disease, 783 gene expression induced by endotoxin, 61 transforming growth factor-p and receptor expres- Cytomegalovirus infection sion in meningioma cells, 633 localization of 2.7-kb early gene in, 1247 vascular smooth muscle producing granulocyte- phenotype of villous stromal cells in, 835 macrophage colony-stimulating factor, 421 VCAM-1 expression in AIDS encephalitis, 1021 Breast Dendritic cells cancer of, cathepsin D in, 1003 dermal, Thy-1 expression in mycosis fungoides, fodrin distribution in epithelial hyperplasia, 285 1373 peripheral, reactivity with CD5 monoclonal anti- bodies, 789 Calcification Dexamethasone of aortic allografts in rats, 487 and renal tubular cell la expression, 743 Carcinoma Diabetes mellitus basal cell, p53 overexpression in, 25 non-insulin-dependent, animal model of, 761 of breast, cathepsin D in, 1003 transfer in BB/Wor rat affected by anti-CD2 mono- cervical, keratin expression in, 497 clonal antibodies, 1043 hepatocellular, hepatitis C virus replication in, Dupuytren's contracture 1271 basic fibroblast growth factor in, 661 oral squamous cell, collagenase in, 301 renal cell, integrin distributions in, 1161 squamous cell, PCNA expression in, 139 Editorial, 1 Cathepsin D Elastase in breast carcinoma, 1003 neutrophil, detection in lungs, 153 Index of Subjects 1523 AJP December 1992, Vol. 141, No. 6

Endothelin Heart peptide synthesis by glomerular epithelial cells, actin mRNA abundance affected by anthracy- 279 clines, 1187 Endotoxin coxsackievirus-induced myocarditis affected by and cytokine gene expression in vivo, 61 heparin, 203 effects on intrapulmonary mucosubstances, 307 development after heterotopic transplantation, 183 Epstein-Barr virus myocyte changes in anemia, 227 in AIDS-related CNS lymphoma, 441 transplanted, atherosclerosis in, 1139 genome detection in lymphomas, 457 Heat shock protein 72 Erythema multiforme in meningitis, 53 T cells expressing HECA-452 in, 691 Helicobacter pylori Eyes and peptic ulcer disease, 721 cytokeratins in uveal melanoma, 169 Heparin interleukin-8 induced corneal neovascularization, protective effects in coxsackievirus-induced myo- 1279 carditis, 203 photoreceptor proteins expressed in retinoblasto- Hepatitis C virus ma, 363 replication in liver carcinoma, 1271 Heterokaryons programmed cell death in, 1471 Fetal tissue Hodgkin's disease P-glycoprotein expression in, 1063 lack of bcl-2 gene translocation in, 193 a-Fetoprotein Reed-Sternberg cells in. See Reed-Sternberg cells expression in hepatic hyperplasia and preneopla- Hu antigen sia, 623 expression in normal and tumor tissues, 881 Fibrinogen Hypertension derivatives in aortic intimas, 861 hyperoxic pulmonary, and contractile cells in lung receptors on platelets, 707 microvessels, 1491 Fibroblast growth factor, basic and tenascin expression in vascular smooth mus- in Dupuytren's contracture, 661 cle cells, 377 and glomerular epithelial growth, 107 Flow cytometry pulmonary, in diagnosis of malignancies, 211 Immune system Fodrin human-murine chimeras with high human Ig levels and epithelial proliferative disease of breast, 285 and graft-versus-host disease, 1097 Immunodeficiency virus human, regulatory proteins expressed in normal P-Glycoprotein tissue, 1209 expression in fetal tissues, 1063 simian Graft-versus-host disease in genital tract of female rhesus monkeys, 655 acute cutaneous, T cells expressing HECA-452 in, and VCAM-1 expression in AIDS encephalitis, 691 1021 in human-murine chimeras, 1097 Immunoelectron microscopy Granulocytes of amyloid-like fibrillary glomerulopathy, 409 recessive defect caused by integrated transgene, of neurofibrillary tangles, 343 1237 Immunoglobulins Granuloma initiation factor heavy chain gene rearrangements detected with isolation and characterization of, 1445 rapid polymerase chain reaction, 1291 Granulosa cell tumors In situ hybridization juvenile, fluorescence in-situ hybridization in, 1265 in juvenile granulosa cell tumors, 1265 Growth factors nonradioactive, 579 alterations in metastatic cancer cells, 519 of p53 tumor suppressor gene, 545 Growth hormone-releasing hormone Integrins gene expression in pituitary, liver, and pancreas, distribution in renal cell carcinomas, 1161 895 role of p1-integrins in T-cell lymphomas, 855 1524 Index of Subjects AJP December 1992, Vol. 141, No. 6

Interleukins tubular cell la expression affected by dexametha- IL-1 sone, 743 gene expression induced by endotoxin, 61 vimentin metaplasia in cortical tubules, 955 interaction with platelet activating factor in alve- Koilocytotic lesions olitis, 551 vulvar and cervical, tenascin in, 907 IL-4 in T-cell rich B-cell lymphomas, 1031 IL-6 Laminin expression in Reed-Sternberg cells, 129 receptor mRNA in cancer cell lines, 1073 inhibiting mesangial cell growth, 327 Leukemia secretion by mesangial cells, 429 and nuclear segmentation from chimeric helix- significance in B-cell lymphomas, 915 loop-helix gene, 1125 IL-8 Lipid inducing corneal neovascularization, 1279 aortic deposits after cholesterol feedings, 925 neutrophil-derived, 397 Lipoprotein Intestines epitopes in xanthomas, 99 crypt stem cell organization, 773 Liver distribution of collagenase and its inhibitor in co- albumin and alpha-fetoprotein expression in hy- lorectal cancer, 389 perplasia and preneoplasia, 623 laminin receptor mRNA in colorectal tumors, 1073 alcoholic disease, 69 nuclear morphology and genetics in colorectal tu- changes from growth hormone-releasing hormone mors, 797 gene expression, 895 peripheral T-cell lymphomas of, 1361 hepatitis C virus replication in carcinoma, 1271 woodchuck hepatitis virus infection with renal im- KC gene munopathology, 143 expression in pulmonary inflammation, 981 Lungs Keratin animal model of cryptococcosis, 1517 expression in cervical cancer, 497 bleomycin-stimulated alveolar macrophages, 965 Kidneys chemotactic agent affecting particle-induced fi- changes in glomerular basement membrane after brosis, 319 subtotal nephrectomy, 1481 contractile cells in microvessels in hyperoxic pul- endothelin peptide synthesis in glomerular epithe- monary hypertension, 1491 lial cells, 279 detection of extracellular neutrophil elastase in, 153 extracellular matrix accumulation in PAN nephro- endotoxin effects on intrapulmonary mucosub- sis, 1381 stances, 307 glomerular epithelial cell matrix receptors, 571 flow cytometry in diagnosis of malignancies, 211 glomerular epithelial growth affected by basic fi- interaction of IL-1 and platelet-activating factor in broblast growth factor, 107 alveolitis, 551 glomerular filtration slits in experimental nephrosis, macrophage inflammatory protein-2 and KC gene 805 in inflammation, 981 glomerular macrophages and mesangial cell pro- mineral-induced manganese superoxide dismu- liferation, 887 tase protein in type 11 cells, 475 immunoelectron microscopy of fibrillary glomerul- PCNA immunostaining with PC10 in cancer, 1285 opathy, 409 small cell cancer with bone marrow metastases, immunopathology in woodchuck hepatitis virus in- 531 fection, 143 thrombomodulin in mesothelioma and adenocar- integrin distribution in renal cell carcinomas, 1161 cinoma, 827 mesangial cell growth inhibition by interleukin-6, Lyme borreliosis 327 and cystitis in mice, 1173 mesangial cell-matrix interactions, 429 in NIH-3 mice, 3 mesangial metalloproteases in glomerulonephritis, Lymph nodes 85 peripheral, high endothelial venules in, 1259 nephritogenic potential of proteoglycans, 561 Lymphocytes plasminogen activator inhibitor-1 deposition in rapid polymerase chain reaction for monoclonal mesangial extracellular matrix, 117 B-cell populations, 1291 Index of Subjects 1525 AJP December 1992, Vol. 141, No. 6

recessive defect caused by integrated transgene, 02-Microglobulin amyloid fibrils 1237 synthesis in cell cultures, 241 T cells expressing HECA-452 in cutaneous acute Monoclonal antibodies graft-versus-host disease and erythema multi- Alz-50 immunoreactivity in brain in Alzheimer's forme, 691 disease, 1459 transmigrating, CD31 in, 843 anti-CD2 affecting transfer of diabetes in BB/Wor Lymphoid tissue rat, 1043 hyperplastic, t(14;18) detection in, 291 against cell surface determinants, nuclear uptake Lymphoma of, 937 AIDS-related, in CNS, Epstein-Barr virus in, 441 PC10 for labeling of PCNA in lung cancer, 1285 B-cell peripheral blood dendritic cell reactivity with CD5, significance of interleukin-6 in, 915 789 T-cell rich, interleukin-4 in, 1031 against tumor necrosis factor, efficacy of, 1197 thymic, adhesion molecules in, 729 two MAbs for detection of PCNA in paraffin- Epstein-Barr virus genome detection in, 457 embedded tissues, 1453 p53 expression in, 1343 Mycosis fungoides T-cell cutaneous expression of Thy-1 in, 1373 ,B1-integrins in, 855 Myeloma, multiple peripheral, of intestines, 1361 proto-oncogenes in, 949 thyroid, follicular colonization in, 43 Myositis inclusion-body, P-amyloid protein in, 31 a2-Macroglobulin receptor in brain, 37 Neoplasia Macrophages alterations in cytokines and growth factors in met- alveolar, stimulation by bleomycin, 965 astatic cancer cells, 519 differentiation in atherosclerosis, 161 blood-brain barrier permeability in experimental glomerular, and mesangial cell proliferation, 887 brain metastases, 1115 inflammatory protein-2 in pulmonary inflammation, bone marrow metastasis in small cell lung cancer, 981 531 tumor-associated, in murine and human neo- cathepsin D in breast carcinoma, 1003 plasms growing in nude mice, 1225 collagenase in oral carcinoma, 301 type and type 11 scavenger receptors, 591 cutaneous, PCNA expression in, 139 Manganese superoxide dismutase protein cytokeratins in uveal melanoma, 169 mineral-induced, in type 11 cells of lungs, 475 differential expression of proteoglycans on mel- Melanoma anoma cell surfaces, 467 differential expression of proteoglycans on cell distribution of collagenase and its inhibitor in co- surfaces, 467 lorectal cancer, 389 free radical-mediated endothelial injury in, 601 Epstein-Barr virus in lymphomas, 441, 457 regulated expression of VCAM-1 in, 1323 estimation of tumor growth fractions in paraffin- uveal, cytokeratin expression in, 169 embedded tissues, 1453 Meningioma flow cytometry in diagnosis of pulmonary malig- transforming growth factor-p and receptor expres- nancies, 211 sion in, 633 fluorescence in-situ hybridization in juvenile gran- Meningitis ulosa cell tumors, 1265 heat shock protein 72 in, 53 follicular colonization in thyroid lymphoma, 43 Mesothelloma free radical-mediated endothelial injury in mel- pleural, thrombomodulin in, 827 anoma, 601 Metalloproteinases giant cell tumors producing matrix metalloprotein- matrix-degrading, produced by giant cell tumors, ases, 611 611 hepatitis C virus replication in hepatocellular car- mesangial, in glomerulonephritis, 85 cinoma, 1271 tissue inhibitor histochemical marker genes for metastatic tumor gene expression in oral carcinoma, 301 cells, 1331 stromal expression in colorectal neoplasia, 389 Hodgkin's disease. See Hodgkin's disease 1526 Index of Subjects AJP December 1992, Vol. 141, No. 6

Hu antigen expression in tumor tissue, 881 p53 protein integrin distributions in renal cell carcinomas, expression in lymphomas, 1343 1161 expression in oral cavity dysplasia, 817 interleukin-4 in T-cell rich B-cell lymphomas, 1031 overexpression in basal cell carcinomas, 25 keratin expression in cervical cancer, 497 in situ hybridization analysis in malignancies, 545 laminin receptor mRNA in cancer cell lines, 1073 Pancreas (CA)n repeats for loss of heterozygosity assay in changes from growth hormone-releasing hormone brain tumors, 777 gene expression, 895 nuclear morphology and genetics in colorectal tu- Papillomavirus mors, 797 expression of L2 and E7 genes in female genital nuclear segmentation from chimeric helix-loop- dysplasias, 1217 helix gene in leukemic cells, 1125 genomes in male urethral cells, 1181 p53 in situ hybridization analysis in malignancies, Peptic ulcer disease 545 Helicobacter pylori in, 721 p53 protein overexpression in basal cell carci- Photodynamic therapy noma, 25 neuronal changes in, 989 PCNA immunostaining with PC10 in lung cancer, Photoreceptors 1285 gene expression in retinoblastoma, 363 peripheral T-cell lymphomas of intestine, 1361 Pituitary gland photoreceptor proteins expressed in retinoblasto- changes from growth hormone-releasing hormone ma, 363 gene expression, 895 proliferative activity in ovarian tumors, 699 Plasminogen activator proto-oncogenes in multiple myeloma, 949 inhibitor-1 deposition in mesangial extracellular regulated expression of VCAM-1 in melanoma, 1323 matrix, 117 significance of interleukin-6 in B-cell lymphomas, Platelets 915 activating factor interaction with IL-1 in alveolitis, 551 synaptophysin expression in brain tumors induced fibrinogen receptors on, 707 by ethyl nitrosourea, 1037 Polymerase chain reaction thrombomodulin in pleural mesothelioma and pul- after ultraviolet fractionation, 539 monary adenocarcinoma, 827 rapid system for monoclonal B-cell populations, transforming growth factor-a localization in ap- 1291 pendageal tumors, 643 Polyoma virus mutant transforming growth factor-,B and receptor expres- tumors induced by, 1409 sion in meningioma cells, 633 Pregnancy tumor-associated macrophages in murine and hu- phenotype of villous stromal cells in villitis, 835 man neoplasms growing in nude mice, 1225 Prion protein tumors induced by polyoma virus mutant, 1409 abnormal distribution in brain, 271 Neovascularization Proliferating cell nuclear antigen (PCNA) corneal, induced by interleukin-8, 1279 in cutaneous neoplasia and verruca vulgaris, 139 in media conditioned by hypoxic smooth muscle detection with two monoclonal antibodies, 1453 cells, 1507 immunohistochemistry in rat aorta, 685 Neurofibrillary tangles immunostaining with PC10 in lung cancer, 1285 immunoelectron microscopy of, 343 suprabasal, in oral cavity dysplasia, 817 Neuropathy Proteoglycans amyloid, 217 differential expression on melanoma cell surfaces, Neutrophils 467 producing interleukin-8, 397 nephritogenic potential of, 561 Proto-oncogenes Oral cavity in multiple myeloma, 949 markers for dysplasia of, 817 Ovaries Reed-Sternberg cells fluorescence in-situ hybridization in juvenile gran- Bauhinia purpurea as marker for, 19 ulosa cell tumors, 1265 interleukin-6 expressed in, 129 proliferative activity in tumors, 699 phenotype heterogeneity in Hodgkin's disease, 11 Index of Subjects 1527 AJP December 1992, Vol. 141, No. 6

Retinoblastoma Transgene Integration photoreceptor proteins expressed in, 363 and recessive defects in lymphocytes or granulo- Retinoid-binding proteins cytes, 1237 localization in cervix, 973 Translocation 14;18 in follicular lymphomas, 193 in reactive lymphoid tissue, 291 E-Selectin Transthyretin and X in cell sialyl-Lewis expression types, 1397 in amyloid deposits in L-Selectin nerves, 217 serum levels affecting amyloid deposition, 451 ligands on peripheral node endothelial lymph high Trisomy 12 venules, 1259 in X juvenile granulosa cell tumors, 1265 Sialyl-Lewis Tumor necrosis factor expression in immune inflammation, processes, monoclonal antibody against, 1197 and lymphoid tissues, 1397 expression on peripheral lymph node high endo- thelial venules, 1259 Ulcers Skin chronic venous, extracellular matrix synthesis dur- p53 protein in basal cell carcinomas, 25 ing healing, 1085 PCNA in neoplasia and verruca vulgaris, 139 peptic, Helicobacter pylori in, 721 T cells expressing HECA-452 in cutaneous acute Ultraviolet fractionation graft-versus-host disease and erythema multi- followed by polymerase chain reaction, 539 forme, 691 Urethral cells Thy-1 expression in mycosis fungoides, 1373 male, papillomavirus genomes in, 1181 transforming growth factor-a localization in ap- Uterus pendageal tumors, 643 keratin expression in cervical cancer, 497 Synaptophysin localization of retinoid-binding proteins in cervix, expression in brain tumors induced by ethyl ni- 973 trosourea, 1037 tenascin in cervical koilocytotic lesions, 907 Syphilis Uveal melanoma phenotype of villous stromal cells in, 835 cytokeratin expression in, 169

Tenascin Vasculature in cervical and vulvar koilocytotic lesions, 907 adhesion molecules on endothelium in atheroscle- expression in vascular smooth muscle cells in hy- rosis, 1427 pertension, 377 allograft calcification in rats, 487 Testicular artery amyloid angiopathy in Alzheimer's disease, 249 structure in rat, 1053 angiogenesis in media conditioned by hypoxic Thrombomodulin smooth muscle cells, 1507 in pleural mesothelioma and pulmonary adenocar- antigenic heterogeneity of endothelium, 673 cinoma, 827 aortic lipid deposits after cholesterol feedings, 925 Thrombospondin contractile cells in lung microvessels in hyperoxic in Alzheimer's disease, 783 pulmonary hypertension, 1491 Thy-1 extracellular matrix synthesis during healing of cutaneous expression in mycosis fungoides, 1373 chronic venous ulcers, 1085 Thymic B-cell lymphoma fatty streaklike lesions induced in culture model of adhesion molecules in, 729 arterial intima, 1435 Thyroid gland fibrinogen derivatives in aortic intimas, 861 lymphoma of, follicular colonization in, 43 high endothelial venules of peripheral lymph Trachea nodes, 1259 basal cell changes during repair of epithelium, 753 interleukin-8 induced corneal neovascularization, Transforming growth factor-a 1279 localization in appendageal tumors, 643 PCNA immunohistochemistry in rat aorta, 685 Transforming growth factor-, regulated expression of VCAM-1 in melanoma, and receptor expression in meningioma cells, 633 1323 1528 Index of Subjects AJP December 1992, Vol. 141, No. 6

smooth muscle cells producing granulocyte- expression of L2 and E7 genes of papillomavirus macrophage colony-stimulating factor in brain, in female genital lesions, 1217 421 hepatitis C virus replication in hepatocellular car- tenascin expression in smooth muscle cells in hy- cinoma, 1271 pertension, 377 HIV regulatory proteins expressed in normal tis- testicular artery structure in rat, 1053 sue, 1209 transient disruptions of endothelial cell plasma localization of 2.7-kb early gene in cytomegalovi- membranes, 1349 rus infection, 1247 transplant atherosclerosis in rat model, 1139 papillomavirus genomes in male urethral cells, 1 181 VCAM-1 in AIDS encephalitis, 1021 phenotype of villous stromal cells in cytomegalo- Vasculitis virus infection, 835 systemic, and endothelial cell injury from activated simian immunodeficiency virus in genital tract of neutrophils, 335 female rhesus monkeys, 655 Verruca vulgaris tumors induced by polyoma virus mutant, 1409 PCNA expression in, 139 and VCAM-1 expression in AIDS encephalitis, 1021 Villous stromal cells woodchuck hepatitis virus infection with renal im- phenotype in chronic villitis, 835 munopathology, 143 Vimentin Vulva metaplasia in renal cortical tubules, 955 tenascin in koilocytotic lesions, 907 Viruses coxsackievirus-induced myocarditis affected by Woodchuck hepatitis virus heparin, 203 infection renal immunopathology in, 143 Epstein-Barr virus genome detection in lympho- mas, 457 Epstein-Barr virus in AIDS-related CNS lymphoma, Xanthomas 441 lipoprotein epitopes in, 99 Index of Authors

Volume 141, 1992

Aamdal S: See Beiske K, Myklebust AT, Aamdal S, Anhalt G: See Finzi E, Ho T, Anhalt G, Hawkins W, Har- Langholm R, Jakobsen E, Fodstad 0, 531 kins R, Horn T, 643 Abbas AK: See Bogen SA, Baldwin HS, Watkins SC, Anichini A: See Jonjic N, Martin-Padura I, Pollicino T, Albelda SM, Abbas AK, 843 Bernasconi S, Jilek P, Bigotti A, Mortarini R, Anichini A, Abbondanzo SL: See Chu WS, Abbondanzo SL, Friz- Parmiani G, Colotta F, Dejana E, Mantovani A, Natali zera G, 11 PG: 1323 Adamson IYR, Prieditis H, Bowden DH: Instillation of Anversa P: See Olivetti G, Quaini F, Lagrasta C, Ricci R, Chemotactic Factor to Silica-injected Lungs Lowers In- Tiberti G, Capasso JM, Anversa P, 227 terstitial Particle Content and Reduces Pulmonary Fi- Aragona E: See Alpini G, Aragona E, Dabeva M, Salvi R, brosis (August), 319 Shafritz DA, Tavoloni N, 623 Adida C: See Hag6ge J, Peraldi MN, Rondeau E, Adida Araki S: See Murakami T, Yi S, Maeda S, Tashiro F, Ya- C, Delarue F, Medcalf R, Schleuning WD, Sraer JD, 1 17 mamura KI, Takahashi K, Shimada K, Araki S, 451 Adler S: Characterization of Glomerular Epithelial Cell Arias A: See Vaquero J, Zurita M, Oya S, Arias A, Mor- Matrix Receptors (September), 571 eno M, Morales C: 1037 Akagi T: See Sarker AB, Akagi T, Jeon HJ, Miyake K, Arstila P: See Auvinen E, Kujari H, Arstila P, Hukkanen V: Murakami 1, Yoshino T, Takahashi K, Nose S, 19 1217 Akyol G: See Gerber MA, Shieh YSC, Shim KS, Thung Askanas V, Engel WK, Alvarez RB: Light and Electron SN, Demetris AJ, Schwartz M, Akyol G, Dash S: 1271 Microscopic Localization of f-amyloid Protein in Mus- Albelda SM: See Bogen SA, Baldwin HS, Watkins SC, cle Biopsies of Patients with Inclusion-body Myositis Albelda SM, Abbas AK, 843 (July), 31 Albino AP: See Shea CR, McNutt NS, Volkenandt M, Aster JC, Kobayashi Y, Shiota M, Mori S, Sklar J: Lugo J, Prioleau PG, Albino AP, 25 Detection of the t(14;18) at Similar Frequencies in Hy- Alexander NJ: See Miller CJ, Vogel P, Alexander NJ, perplastic Lymphoid Tissues from American and Japa- Sutjipto S, Hendrickx AG, Marx PA, 655 nese Patients (August), 291 Allen RM: See Strieter RM, Kasahara K, Allen RM, Stan- Athan E, Chadburn A, Knowles DM: The bcl-2 Gene diford TJ, Rolfe MW, Becker FS, Chensue SW, Kunkel Translocation Is Undetectable in Hodgkin's Disease by SL, 397 Southern Blot Hybridization and Polymerase Chain Re- Alpini G, Aragona E, Dabeva M, Salvi R, Shafritz action (July), 193 DA, Tavoloni N: Distribution of Albumin and Alpha-fe- Auvinen E, Kujari H, Arstila P, Hukkanen V: Expres- toprotein mRNAs in Normal, Hyperplastic, and Preneo- sion of the L2 and E7 Genes of the Human Papilloma- plastic Rat Liver (September), 623 virus Type 16 in Female Genital Dysplasias (No- Alvarez RB: See Askanas V, Engel WK, Alvarez RB, 31 vember): 1217 Anderson JM: See Kurihara H, Anderson JM, Kerjaschki Au WC: See Wu TC, Lee WA, Pizzorno MC, Au WC, D, Farquhar MG, 805 Chan YJ, Hruban RH, Hutchins GM, Hayward GS: Anderson JM: See Valenzuela R, Shainoff JR, DiBello 1247 PM, Urbanic DA, Anderson JM, Matsueda GR, Kudryk BJ, 861 Baird A: See Gonzalez AM, Buscaglia M, Fox R, Isacchi Anderson JP: See Pappolla MA, Omar RA, Sambamurti A, Sarmientos P, Farris J, Ong M, Martineau D, Lappi K, Anderson JP, Robakis NK: 1151 DA, Baird A, 661 Anderson WI: See Peters DN, Steinberg H, Anderson Baldwin HS: See Bogen SA, Baldwin HS, Watkins SC, WI, Hornbuckle WE, Cote PJ, Gerin JL, Lewis RM, Ten- Albelda SM, Abbas AK, 843 nant BC, 143 Barlow AK, Like AA: Anti-CD2 Monoclonal Antibodies Androulakis-Papachristou A: See Isaacson PG, An- Prevent Spontaneous and Adoptive Transfer of Dia- droulakis-Papachristou A, Diss TC, Pan L, Wright DH, betes in the BB/Wor Rat (November): 1043 43 Barnhill RL: See Munro JM, Lo SK, Corless C, Robert- 1529 1530 Index of Authors AJP December 1992, Vol. 141, No. 6

son MJ, Lee NC, Barnhill RL, Weinberg DS, Bevilacqua Valk P, Kuiper CM, Hadisaputro MMN, Bosma SAA, MP: 1397 Scheper RJ, Meijer CJLM, Pinedo HM: 1063 Barrera R: See Said JW, Barrera R, Shintaku IP, Naka- Bowden DH: See Adamson IYR, Prieditis H, Bowden DH, mura H, Koeffler HP: 1343 319 Barrow RE: See Wang CZ, Evans MJ, Cox RA, Burke Brennan DC: See Jevnikar AM, Singer GG, Brennan DC, AS, Zhu Q, Herndon DN, Barrow RE, 753 Xu HW, Kelley VR, 743 Beall D: See Sasseville VG, Newman WA, Lackner AA, Brinster RL: See Lo D, Quill H, Burkly L, Scott B, Palmiter Smith MO, Lausen NCG, Beall D, Ringler D: 1021 RD, Brinster RL: 1237 Becker AE: See van der Wal AC, Das PK, Tigges AJ, Bucana CD, Fabra A, Sanchez R, Fidler IJ: Different Becker AE, 161 Patterns of Macrophage Infiltration into Allogenic and Becker AE: See van der Wal AC, Das PK, Tigges AJ, Xenogeneic-Human Neoplasms Growing in Nude Mice Becker AE: 1427 (November): 1225 Becker FS: See Strieter RM, Kasahara K, Allen RM, Stan- Bucana CD: See Zhang RD, Price JE, Fujimaki T, Bu- diford TJ, Rolfe MW, Becker FS, Chensue SW, Kunkel cana CD, Fidler IJ: 1 115 SL, 397 Buch S: See Jones CL, Buch S, Post M, McCulloch L, Liu Beiske K, Mykiebust AT, Aamdal S, Langholm R, E, Eddy AA: 1381 Jakobsen E, Fodstad 0: Detection of Bone Marrow Buee L, Hof PR, Roberts DD, Delacourte A, Morri- Metastases in Small Cell Lung Cancer Patients: Com- son JH, Fillit HM: Immunohistochemical Identification parison of Immunologic and Morphologic Methods of Thrombospondin in Normal Human Brain and in Alz- (September), 531 heimer's Disease (October), 783 Benjamin TL: See Freund R, Dawe CJ, Carroll JP, Benja- Bohler FR: See Mackie EJ, Scott-Burden T, Hahn AWA, min TL: 1409 Kern F, Bernhardt J, Regenass S, Weller A, Bohler FR, Bernasconi S: See Jonjic N, Martin-Padura I, Pollicino T, 377 Bernasconi S, Jilek P, Bigotti A, Mortarini R, Anichini A, Bui HX: See Ross JS, Bui HX, del Rosario A, Sonbati H, Parmiani G, Colotta F, Dejana E, Mantovani A, Natali George M, Lee CY, 721 PG: 1323 Burke AS: See Wang CZ, Evans MJ, Cox RA, Burke AS, Bernhardt J: See Mackie EJ, Scott-Burden T, Hahn Zhu Q, Herndon DN, Barrow RE, 753 AWA, Kern F, Bernhardt J, Regenass S, Weller A, Burkly L: See Lo D, Quill H, Burkly L, Scott B, Palmiter BUhler FR, 377 RD, Brinster RL: 1237 Bevilacqua MP: See Munro JM, Lo SK, Corless C, Rob- Buscaglia M: See Gonzalez AM, Buscaglia M, Fox R, ertson MJ, Lee NC, Barnhill RL, Weinberg DS, Bevilac- Isacchi A, Sarmientos P, Farris J, Ong M, Martineau D, qua MP: 1397 Lappi DA, Baird A, 661 Bigalke 1: See Offner FA, Wirtz HC, Schiefer J, Bigalke I, Klosterhalfen B, Bittinger F, Mittermayer C, Kirkpatrick Camper SA: See Lloyd RV, Jin L, Chang A, Kulig E, CJ, 601 Camper SA, Ross BD, Downs TR, Frohman LA, 895 Bigini D: See Fontanini G, Pingitore R, Bigini D, Vignati S, Campistol JM, So16 M, Bombi JA, Rodriguez R, Mir- Pepe S, Ruggiero A, Macchiarini P: 1285 apeix E, Mufloz-Gomez J, Revert OW: In Vitro Bigotti A: See Jonjic N, Marfin-Padura I, Pollicino T, Ber- Spontaneous Synthesis of /32-microglobulin Amyloid Fi- nasconi S, Jilek P, Bigotti A, Mortarini R, Anichini A, brils in Peripheral Blood Mononuclear Cell Culture Parmiani G, Colotta F, Dejana E, Mantovani A, Natali (July), 241 PG: 1323 Campo E, Monteagudo C, Castronovo V, Claysmith Bittinger F: See Offner FA, Wirtz HC, Schiefer J, Bigalke AP, Fernandez PL, Sobel ME: Detection of Laminin I, Klosterhalfen B, Bittinger F, Mittermayer C, Kirkpa- Receptor mRNA in Human Cancer Cell Lines and Colo- trick CJ, 601 rectal Tissues by In Situ Hybridization (November): Boehncke WH: See Sterry W, Mielke V, Konter U, 1073 Kellner I, Boehncke WH, 855 Capasso JM: See Olivetti G, Quaini F, Lagrasta C, Ricci Bogaert M: See Penneys NS, Bogaert M, Serfling U, R, Tiberti G, Capasso JM, Anversa P, 227 Sisto M, 139 Carroll JP: See Freund R, Dawe CJ, Carroll JP, Benjamin Bogen SA, Baldwin HS, Watkins SC, Albelda SM, TL: 1409 Abbas AK: Association of Murine CD31 with Transmi- Castronovo V: See Campo E, Monteagudo C, Castron- grating Lymphocytes Following Antigenic Stimulation ovo V, Claysmith AP, Fernandez PL, Sobel ME: 1073 (October), 843 Cercek B: See Zeymer U, Fishbein MC, Forrester JS, Bombi JA: See Campistol JM, Sol6 M, Bombi JA, Rodri- Cercek B, 685 guez R, Mirapeix E, Munoz-Gomez J, Revert OW, 241 Chadburn A: See Athan E, Chadburn A, Knowles DM, Bosma SAA: See van Kalken CK, Giaccone G, van der 193 Index of Authors 1531 AJP December 1992, Vol. 141, No. 6

Chait A: See Sugiyama N, Marcovina S, Gown AM, Seftel Cox RA: See Wang CZ, Evans MJ, Cox RA, Burke AS, H, Joffe B, Chait A, 99 Zhu Q, Herndon DN, Barrow RE, 753 Chang A: See Lloyd RV, Jin L, Chang A, Kulig E, Camper Crabb ID, Hughes SS, Hicks DG, Puzas JE, Tsao SA, Ross BD, Downs TR, Frohman LA, 895 GJY, Rosier RN: Nonradioactive In Situ Hybridization Chan YJ: See Wu TC, Lee WA, Pizzorno MC, Au WC, Using Digoxigenin-labeled Oligonucleotides: Applica- Chan YJ, Hruban RH, Hutchins GM, Hayward GS: tions to Musculoskeletal Tissues (September), 579 1247 Culp LA: See Lin WC, Pretlow TP, Pretlow TG 11, Culp LA: Chensue SW: See Strieter RM, Kasahara K, Allen RM, 1331 Standiford TJ, Rolfe MW, Becker FS, Chensue SW, Czub S, Duray PH, Thomas RE, Schwan TG: Cystitis Kunkel SL, 397 in Mice Induced by Infection with the Lyme Disease Chong J: See de la Monte SM, Spratt RA, Chong J, Spirochete, Borrelia burgdorferi (November): 1 173 Ghanbari HA, Wands JR: 1459 Chopp M: See Yoshida Y, Dereski MO, Garcia JH, Hetzel FW, Chopp M, 989 Dabeva M: See Alpini G, Aragona E, Dabeva M, Salvi R, Chott A, Dragosics B, Radaszkiewicz T: Peripheral Shafritz DA, Tavoloni N, 623 T-cell Lymphomas of the Intestine (December): 1361 Dalmau J, Furneaux HM, Cordon-Cardo C, Posner Chu WS, Abbondanzo SL, Frizzera G: Inconsistency JB: The Expression of the Hu (Paraneoplastic Encepha- of the Immunophenotype of Reed-Sternberg Cells in lomyelitis/Sensory Neuronopathy) Antigen in Human Simultaneous and Consecutive Specimens from the Normal and Tumor Tissues (October), 881 Same Patients: A Paraffin Section Evaluation in 56 Pa- Dash S: See Gerber MA, Shieh YSC, Shim KS, Thung tients (July), 11 SN, Demetris AJ, Schwartz M, Akyol G, Dash S: 1271 Claysmith AP: See Campo E, Monteagudo C, Castron- Das PK: See van der Wal AC, Das PK, Tigges AJ, Becker ovo V, Claysmith AP, Fernandez PL, Sobel ME: A9 AE, 161 Coleman DL: See Ruef C, Kashgarian M, Coleman DL, Das PK: See van der Wal AC, Das PK, Tigges AJ, Becker 429 AE: 1427 Collins CL, Ordonez NG, Schaefer R, Cook CD, Xie Davalath S: See Kasinath BS, Fried TA, Davalath S, SS, Granger J, Hsu PL, Fink L, Hsu SM: Thrombo- Marsden PA, 279 modulin Expression in Malignant Pleural Mesothelioma Davies M: See Lovett DH, Johnson RJ, Marti HP, Martin and Pulmonary Adenocarcinoma (October), 827 J, Davies M, Couser WG, 85 Colotta F: See Ber- Jonjic N, Marfin-Padura I, Pollicino T, Davis RE, Smoller BR: T Lymphocytes Expressing nasconi S, Jflek P, Bigotti A, Mortarini R, Anichini A, HECA-452 Epitope Are Present in Cutaneous Acute Parmiani G, Colotta F, Dejana E, Mantovani A, Natali Graft-versus-Host Disease and Erythema PG: 1323 Multiforme, But Not in Acute Graft-versus-Host Disease in Gut Or- Coltrera MD, Zarbo RJ, Sakr WA, Gown AM: Markers gans (September), 691 for Dysplasia of the Upper Aerodigestive Tract: Supra- basal Expression of PCNA, p53, and CK19 in Alcohol- Dawe CJ: See Freund R, Dawe CJ, Carroll JP, Benjamin fixed, Embedded Tissue (October), 817 TL: 1409 Cook CD: See Collins CL, Ordonez NG, Schaefer R, de Campos Lima PO: See Della Torre G, Donghi R, de Cook CD, Xie SS, Granger J, Hsu PL, Fink L, Hsu SM, Campos Lima PO, Pasquini G, Pilotti S, Koronel R, Pier- 827 otti MA, De Palo G, Della Porta G, Rilke F: 1181 Cordon-Cardo C: See Dalmau J, Furneaux HM, Cordon- de Feyter EP: See Mulder JWR, Offerhaus GJA, de Cardo C, Posner JB, 881 Feyter EP, Floyd JJ, Kern SE, Vogelstein B, Hamilton Corless C: See Munro JM, Lo SK, Corless C, Robertson SR, 797 MJ, Lee NC, Barnhill RL, Weinberg DS, Bevilacqua MP: Defosse DL, Duray PH, Johnson RC: The NIH-3 lmmu- 1397 nodeficient Mouse Is a Model for Lyme Borreliosis Myo- Cote PJ: See Peters DN, Steinberg H, Anderson WI, sitis and Carditis (July), 3 Hornbuckle WE, Cote PJ, Gerin JL, Lewis RM, Tennant De Grip WJ: See Gonzalez-Fernandez F, Lopes MBS, BC, 143 Garcia-Fernandez JM, Foster RG, De Grip WJ, Rosem- Cousar JB: See Macon WR, Cousar JB, Waldron JA Jr, berg S, Newman SA, VandenBerg SR, 363 Hsu SM: 1031 Dejana E: See Jonjic N, Martin-Padura I, Pollicino T, Ber- Couser WG: See Lovett DH, Johnson RJ, Marti HP, Mar- nasconi S, Jilek P, Bigotti A, Mortarini R, Anichini A, tin J, Davies M, Couser WG, 85 Parmiani G, Colotta F, Dejana E, Mantovani A, Natali Coutard M, Osborne-Pellegrin M: The Rat Testicular PG: 1323 Artery: A Model of Spontaneous Aneurysmal-like Struc- Delacourte A: See Bu6e L, Hof PR, Roberts DD, Dela- ture Formation (November): 1053 courte A, Morrison JH, Fillit HM, 783 1532 Index of Authors AJP December 1992, Vol. 141, No. 6 de la Monte SM, Spratt RA, Chong J, Ghanbari HA, Diss TC: See Isaacson PG, Androulakis-Papachristou A, Wands JR: Immunohistochemical and Histopatho- Diss TC, Pan L, Wright DH, 43 logic Correlates of Alzheimer's Disease-Associated Diwan BA: See Ward JM, Stevens JL, Konishi N, Kurata Alz-50 Immunoreactivity Quantified in Homogenates of Y, Uno H, Diwan BA, Ohmori T, 955 Cerebral Tissue (December): 1459 Dixon FJ: See Duchosal MA, Eming SA, McConahey PJ, Delarue F: See Hag6ge J, Peraldi MN, Rondeau E, Adida Dixon FJ: 1097 C, Delarue F, Medcalf R, Schleuning WD, Sraer JD, 1 17 Doh-ura K: See Kitamoto T, Doh-ura K, Muramoto T, del Castillo J: See Ulich TR, Guo K, Yin S, del Castillo J, Miyazono M, Tateishi J, 271 Yi ES, Thompson RC, Eisenberg SP, 61 Domagala W, Striker G, Szadowska A, Dukowicz A, Della Porta G: See Della Torre G, Donghi R, de Campos Weber K, Osborn M: Cathepsin D in Invasive Ductal Lima PO, Pasquini G, Pilotti S, Koronel R, Pierotti MA, NOS Breast Carcinoma as Defined by Immunohisto- De Palo G, Della Porta G, Rilke F: 1181 chemistry: No Correlation with Survival at 5 Years (No- Della Torre G, Donghi R, de Campos Lima PO, Pas- vember): 1003 quini G, Pilotti S, Koronel R, Pierotti MA, De Palo Donghi R: See Della Torre G, Donghi R, de Campos G, Della Porta G, Rilke F: Human Papillomavirus Ge- Lima PO, Pasquini G, Pilotti S, Koronel R, Pierotti MA, nomes in Male Urethral Cells (November): 1181 De Palo G, Della Porta G, Rilke F: 1 181 del Rosario A: See Ross JS, Bui HX, del Rosario A, Douglass MC: See Fivenson DP, Douglass MC, Nicko- Sonbati H, George M, Lee CY, 721 loff BJ: 1373 Demetris AJ: See Gerber MA, Shieh YSC, Shim KS, Downs TR: See Lloyd RV, Jin L, Chang A, Kulig E, Thung SN, Demetris AJ, Schwartz M, Akyol G, Dash S: Camper SA, Ross BD, Downs TR, Frohman LA, 895 1271 Dragosics B: See Chott A, Dragosics B, Radaszkiewicz Demopoulos RI: See Greco MA, Wieczorek R, Sachdev T: 1361 R, Kaplan C, Nuovo GJ, Demopoulos RI, 835 Dubrulle MP, Terzi F, Gubler MC, Kleinknecht C, Denholm EM: Continuous Secretion of Monocyte Che- Schaeverbeke M: Changes in Thickness and Anionic motactic Factors and Fibroblast Growth Factors by Al- Sites of the Glomerular Basement Membrane After veolar Macrophages Following a Single Exposure to Subtotal Nephrectomy in the Rat (December): 1481 Bleomycin In Vitro (October), 965 Duchosal MA, Eming SA, McConahey PJ, Dixon FJ: Denk H: See Dinges HP, Zatloukal K, Denk H, Smolle J, Characterization of hu-PBL-SCID Mice with High Hu- Mair S, 69 man Immunoglobulin Serum Levels and Graft-versus- De Palo G: See Della Torre G, Donghi R, de Campos Host Disease (November): 1097 Lima PO, Pasquini G, Pilotti S, Koronel R, Pierotti MA, Duerr M: See Jesmok G, Lindsey C, Duerr M, Fournel M, De Palo G, Della Porta G, Rilke F: 1181 Emerson T Jr: 1 197 Dereski MO: See Yoshida Y, Dereski MO, Garcia JH, Dukowicz A: See Domagala W, Striker G, Szadowska A, Hetzel FW, Chopp M, 989 Dukowicz A, Weber K, Osborn M: 1003 Diamond IP: See Diamond JR, Ding G, Frye J, Diamond Duray PH: See Czub S, Duray PH, Thomas RE, Schwan IP, 887 TG: 1173 Diamond JR, Ding G, Frye J, Diamond IP: Glomerular Duray PH: See Defosse DL, Duray PH, Johnson RC, 3 Macrophages and the Mesangial Proliferative Re- Dvorak AM, Warner JA, Morgan E, Kissell-Rainville sponse in the Experimental Nephrotic Syndrome (Oc- S, Lichtenstein LM, MacGlashan DW Jr: An Ultra- tober), 887 structural Analysis of Tumor-promoting Phorbol Dies- DiBello PM: See Valenzuela R, Shainoff JR, DiBello PM, ter-induced Degranulation of Human Basophils (De- Urbanic DA, Anderson JM, Matsueda GR, Kudryk BJ, cember): 1309 861 Dyck PJ: See li K, Kyle RA, Dyck PJ, 217 Dijkman JH: See Rudolphus A, Stolk J, van Twisk C, van Noorden CJF, Dijkman JH, Kramps JA, 153 Eddy AA: See Jones CL, Buch S, Post M, McCulloch L, Dinges HP, Zatloukal K, Denk H, Smolle J, Mair S: Liu E, Eddy AA: 1381 Alcoholic Liver Disease: Parenchyma to Stroma Rela- Eichelmann A, Koretz K, Mechtersheimer G, Moller tionship in Fibrosis and Cirrhosis as Revealed by P: Adhesion Receptor Profile of Thymic B-cell Lym- Three-dimensional Reconstruction and Immunohisto- phoma (September), 729 chemistry (July), 69 Eisenberg SP: See Ulich TR, Guo K, Yin S, del Castillo J, Ding G: See Diamond JR, Ding G, Frye J, Diamond IP, Yi ES, Thompson RC, Eisenberg SP, 61 887 Ellis WG: See Murphy GM Jr, Greenberg BD, Ellis WG, Dipasquale B, Youle RJ: Programmed Cell Death in Forno LS, Salamat SM, Gonzalez-DeWhitt PA, Lowery Heterokaryons (December): 1471 DE, Tinklenberg JR, Eng LF, 357 Index of Authors 1533 AJP December 1992, Vol. 141, No. 6

Elner SG: See Strieter RM, Kunkel SL, Elner VM, Mar- Fivenson DP, Douglass MC, Nickoloff BJ: Cutaneous tonyi CL, Koch AE, Polverini PJ, Elner SG: 1279 Expression of Thy-1 in Mycosis Fungoides (De- Elner VM: See Strieter RM, Kunkel SL, Elner VM, Mar- cember): 1373 tonyi CL, Koch AE, Polverini PJ, Elner SG: 1279 Flaris NA, Hickey WF: Development and Characteriza- Emerson T Jr: See Jesmok G, Lindsey C, Duerr M, Four- tion of an Experimental Model of Brain Abscess in the nel M, Emerson T Jr: 1 197 Rat (December): 1299 Eming SA: See Duchosal MA, Eming SA, McConahey Fletcher JA: See Schofield DE, Fletcher JA: 1265 PJ, Dixon FJ: 1097 Floyd JJ: See Mulder JWR, Offerhaus GJA, de Feyter Engel WK: See Askanas V, Engel WK, Alvarez RB, 31 EP, Floyd JJ, Kern SE, Vogelstein B, Hamilton SR, 797 Eng LF: See Murphy GM Jr, Greenberg BD, Ellis WG, Fodstad 0: See Beiske K, Myklebust AT, Aamdal S, Forno LS, Salamat SM, Gonzalez-DeWhitt PA, Lowery Langholm R, Jakobsen E, Fodstad 0, 531 DE, Tinklenberg JR, Eng LF, 357 Fontanini G, Pingitore R, Bigini D, Vignati S, Pepe S, Epstein WL: See Fung MA, Sato N, lida T, Fukuyama K, Ruggiero A, Macchiarini P: Growth Fraction in Non- Epstein WL: 1445 small Cell Lung Cancer Estimated by Proliferating Cell Evans MJ: See Wang CZ, Evans MJ, Cox RA, Burke AS, Nuclear Antigen and Comparison with Ki-67 Labeling Zhu Q, Herndon DN, Barrow RE, 753 and DNA Flow Cytometry Data (December): 1285 Forno LS: See Murphy GM Jr, Greenberg BD, Ellis WG, Fabra A: See Bucana CD, Fabra A, Sanchez R, Fidler IJ: Forno LS, Salamat SM, Gonzalez-DeWhitt PA, Lowery 1225 DE, Tinklenberg JR, Eng LF, 357 Fabry Z: See Hart MN, Fabry Z, Love-Homan L, Keiner J, Forrester JS: See Zeymer U, Fishbein MC, Forrester JS, Sadewasser KL, Moore SA, 421 Cercek B, 685 Fan J: See Yamada T, Fan J, Shimokamam T, Tokunaga Foster RG: See Gonzalez-Fernandez F, Lopes MBS, 0, Watanabe T: 1435 Garcia-Fernandez JM, Foster RG, De Grip WJ, Rosem- Farquhar MG: See Kurihara H, Anderson JM, Kerjaschki berg S, Newman SA, VandenBerg SR, 363 D, Farquhar MG, 805 Fournel M: See Jesmok G, Lindsey C, Duerr M, Fournel Farris J: See Gonzalez AM, Buscaglia M, Fox R, Isacchi M, Emerson T Jr: 1197 A, Sarmientos P, Farris J, Ong M, Martineau D, Lappi Fox R: See Gonzalez AM, Buscaglia M, Fox R, Isacchi A, DA, Baird A, 661 Sarmientos P, Farris J, Ong M, Martineau D, Lappi DA, Fausto N: A New Phase for The AJP (July), 1 Baird A, 661 Federspiel CF: See Johnson MD, Federspiel CF, Gold Freak L: See Herrick SE, Sloan P, McGurk M, Freak L, LI, Moses HL, 633 McCollum CN, Ferguson MWJ: 1085 Feiner H: See Ladanyi M, Wang S, Niesvizky R, Feiner H, Freudenthal PS: See Wood GS, Freudenthal PS, 789 Michaeli J, 949 Freund R, Dawe CJ, Carroll JP, Benjamin TL: Ferguson M: See Isik FF, McDonald TO, Ferguson M, Changes in Frequency, Morphology, and Behavior of Yamanaka E, Gordon D: 1 139 Tumors Induced in Mice by a Polyoma Virus Mutant Ferguson MWJ: See Herrick SE, Sloan P, McGurk M, with a Specifically Altered Oncogene (December): Freak L, McCollum CN, Ferguson MWJ: 1085 1409 Fernandez PL: See Campo E, Monteagudo C, Castron- Fried TA: See Kasinath BS, Fried TA, Davalath S, Mars- ovo V, Claysmith AP, Fernandez PL, Sobel ME: 1073 den PA, 279 Fidler IJ: See Bucana CD, Fabra A, Sanchez R, Fidler IJ: Frizelle S, Schwarz J, Huber SA, Leslie K: Evaluation 1225 of the Effects of Low Molecular Weight Heparin on In- Fidler IJ: See Zhang RD, Price JE, Fujimaki T, Bucana flammation and Collagen Deposition in Chronic Cox- CD, Fidler IJ: 1 1 15 sackievirus B3-induced Myocarditis in A/J Mice (July), Fillit HM: See Buee L, Hof PR, Roberts DD, Delacourte A, 203 Morrison JH, Fillit HM, 783 Frizzera G: See Chu WS, Abbondanzo SL, Frizzera G, Fink L: See Collins CL, Ordonez NG, Schaefer R, Cook 11 CD, Xie SS, Granger J, Hsu PL, Fink L, Hsu SM, 827 Frohman LA: See Lloyd RV, Jin L, Chang A, Kulig E, Finzi E, Ho T, Anhalt G, Hawkins W, Harkins R, Horn Camper SA, Ross BD, Downs TR, Frohman LA, 895 T: Localization of Transforming Growth Factor-a in Hu- Frojmovic M: See Hensler ME, Frojmovic M, Taylor RG, man Appendageal Tumors (September), 643 Hantgan RR, Lewis JC, 707 Fishbein MC: See Zeymer U, Fishbein MC, Forrester JS, Frosch MP: See Yamaguchi H, Yamazaki T, Lemere CA, Cercek B, 685 Frosch MP, Selkoe DJ, 249 Fishleder AJ: See Segal GH, Wittwer CT, Fishleder AJ, Frye J: See Diamond JR, Ding G, Frye J, Diamond IP, Stoler MH, Tubbs RR, Kjeldsberg CR: 1291 887 1534 Index of Authors AJP December 1992, Vol. 141, No. 6

Fuchs U, Kivela T, Summanen P, Immonen I, Tark- Gold LI: See Johnson MD, Federspiel CF, Gold Li, kanen A: An Immunohistochemical and Prognostic Moses HL, 633 Analysis of Cytokeratin Expression in Malignant Uveal Goller NL: See Wrzolek MA, Merz PA, Kascsak R, Melanoma (July), 169 Grundke-lqbal I, lqbal K, Rubenstein R, Tonna-DeMasi Fuhr JE, Kattine AA, Sullivan TA, Nelson HS Jr: Flow M, Goller NL, Mehta P, Wisniewski HM, 343 Cytometric Analysis of Pulmonary Fluids and Cells for Gonias SL: See Wolf BB, Lopes MBS, VandenBerg SR, the Detection of Malignancies (July), 211 Gonias SL, 37 Fujimaki T: See Zhang RD, Price JE, Fujimaki T, Bucana Gonzalez AM, Buscaglia M, Fox R, lsacchi A, Sar- CD, Fidler IJ: 11 15 mientos P, Farris J, Ong M, Martineau D, Lappi Fukuyama K: See Fung MA, Sato N, lida T, Fukuyama K, DA, Baird A: Basic Fibroblast Growth Factor in Dupuy- Epstein WL: 1445 tren's Contracture (September), 661 Fung MA, Sato N, lida T, Fukuyama K, Epstein WL: Gonzalez-DeWhitt PA: See Murphy GM Jr, Greenberg Isolation and Characterization of Granuloma Initiation BD, Ellis WG, Forno LS, Salamat SM, Gonzalez-De- Factor (December): 1445 Whitt PA, Lowery DE, Tinklenberg JR, Eng LF, 357 Furneaux HM: See Dalmau J, Furneaux HM, Cordon- Gonzalez-Fernandez F, Lopes MBS, Garcia-Fer- Cardo C, Posner JB, 881 nandez JM, Foster RG, De Grip WJ, Rosemberg Fuse Y: See Takeuchi A, Yoshizawa N, Yamamoto M, S, Newman SA, VandenBerg SR: Expression of De- Sawasaki Y, Oda T, Senoo A, Niwa H, Fuse Y, 107 velopmentally Defined Retinal Phenotypes in the Histo- genesis of Retinoblastoma (August), 363 Gallo GR: See Yang GCH, Nieto R, Stachura I, Gallo GR, Gordon D: See Isik FF, McDonald TO, Ferguson M, Ya- 409 manaka E, Gordon D: 1 139 Garcia-Fernandez JM: See Gonzalez-Fernandez F, Goukon Y: See Sasano H, Goukon Y, Nishihira T, Na- Lopes MBS, Garcia-Fernandez JM, Foster RG, De Grip gura H, 545 WJ, Rosemberg S, Newman SA, VandenBerg SR, 363 Gouldsmit J: See Parmentier HK, van Wichen DF, Mey- Garc:ia JH: See Yoshida Y, Dereski MO, Garcia JH, Het- ling FHJG, Gouldsmit J, Schuurman HJ: 1209 zel FW, Chopp M, 989 Gould VE: See Korhonen M, Laitinen L, Ylanne J, Kou- Gaskin G: See Savage COS, Pottinger BE, Gaskin G, koulis GK, Quaranta V, Juusela H, Gould VE, Virtanen I: Pusey CD, Pearson JD, 335 1161 Gelb AB, Kamel OW, LeBrun DP, Warnke RA: Esti- Gould VE: See Tiitta 0, WahlstrOm T, Paavonen J, Lin- mation of Tumor Growth Fractions in Archival Formalin- nala A, Sharma S, Gould VE, Virtanen I, 907 fixed, Paraffin-embedded Tissues Using Two Anti- Gown AM: See Coltrera MD, Zarbo RJ, Sakr WA, Gown PCNA/Cyclin Monoclonal Antibodies (December): AM, 817 1453 Gown AM: See Sugiyama N, Marcovina S, Gown AM, George M: See Ross JS, Bui HX, del Rosario A, Sonbati Seftel H, Joffe B, Chait A, 99 H, George M, Lee CY, 721 Granger J: See Collins CL, Ordonez NG, Schaefer R, Gerber MA, Shieh YSC, Shim KS, Thung SN, Deme- Cook CD, Xie SS, Granger J, Hsu PL, Fink L, Hsu SM, tris AJ, Schwartz M, Akyol G, Dash S: Detection of 827 Replicative Hepatitis C Virus Sequences in Hepatocel- Gray ST, Wilkins RJ, Yun K: Interstitial Collagenase lular Carcinoma (December): 1271 Gene Expression in Oral Squamous Cell Carcinoma Gerin JL: See Peters DN, Steinberg H, Anderson WI, (August), 301 Hornbuckle WE, Cote PJ, Gerin JL, Lewis RM, Tennant Greco MA, Wieczorek R, Sachdev R, Kaplan C, BC, 143 Nuovo GJ, Demopoulos RI: Phenotype of Villous Stromal Cells in Placentas with Cytomegalovirus, Syphi- Ghanbari HA: See de la Monte SM, RA, Spratt Chong J, lis, and Nonspecific Villitis (October), 835 Ghanbari HA, Wands JR: 1459 Greenberg BD: See Murphy GM Jr, Greenberg BD, Ellis Giaccone G: See van Kalken CK, Giaccone G, van der WG, Forno LS, Salamat SM, Gonzalez-DeWhitt PA, Lo- Valk P, Kuiper CM, Hadisaputro MMN, Bosma SAA, wery DE, Tinklenberg JR, Eng LF, 357 Scheper RJ, Meijer CJLM, Pinedo HM: 1063 Greenberg JM: See Goldfarb AN, Wolf ML, Greenberg Godleski JJ: See Huang S, Paulauskis JD, Godleski JJ, JM: 1125 Kobzik L, 981 Grogan TM: See Ross CW, Schlegelmilch JA, Grogan Goldfarb AN, Wolf ML, Greenberg JM: Expression of TM, Weiss LM, Schnitzer B, Hanson CA, 457 a Chimeric Helix-Loop-Helix Gene, Id-SCL, in K562 Hu- Grundke-lqbal 1: See Wrzolek MA, Merz PA, Kascsak R, man Leukemic Nuclear Segmentation (November): Grundke-lqbal I, lqbal K, Rubenstein R, Tonna-DeMasi 1125 M, Goller NL, Mehta P, Wisniewski HM, 343 Index of Authors 1535 AJP December 1992, Vol. 141, No. 6

Gubler MC: See Dubrulle MP, Terzi F, Gubler MC, Kleink- Hernandez AM: See Shibata D, Hawes D, Li ZH, Her- necht C, Schaeverbeke M: 1481 nandez AM, Spruck CH, Nichols PW, 539 Guo K: See Ulich TR, Guo K, Yin S, del Castillo J, Yi ES, Herndon DN: See Wang CZ, Evans MJ, Cox RA, Burke Thompson RC, Eisenberg SP, 61 AS, Zhu Q, Herndon DN, Barrow RE, 753 Guyton JR, Klemp KF: Early Extracellular and Cellular Herrick SE, Sloan P, McGurk M, Freak L, McCollum Lipid Deposits in Aorta of Cholesterol-fed Rabbits (Oc- CN, Ferguson MWJ: Sequential Changes in Histo- tober), 925 logic Pattern and Extracellular Matrix Deposition During the Healing of Chronic Venous Ulcers (November): Hadisaputro MMN: See van Kalken CK, Giaccone G, 1085 van der Valk P, Kuiper CM, Hadisaputro MMN, Bosma Hetzel FW: See Yoshida Y, Dereski MO, Garcia JH, Het- SAA, Scheper RJ, Meijer CJLM, Pinedo HM: 1063 zel FW, Chopp M, 989 Hagege J, Peraldi MN, Rondeau E, Adida C, De- Hickey WF: See Flaris NA, Hickey WF: 1299 larue F, Medcalf R, Schleuning WD, Sraer JD: Hicks DG: See Crabb ID, Hughes SS, Hicks DG, Puzas Plasminogen Activator Inhibitor-1 Deposition in the Ex- JE, Tsao GJY, Rosier RN, 579 tracellular Matrix of Cultured Human Mesangial Cells Hillemanns P, Tannous-Khuri L, Koulos JP, Tal- (July), 117 mage D, Wright TC Jr: Localization of Cellular Reti- Hahn AWA: See Mackie EJ, Scott-Burden T, Hahn AWA, noid-binding Proteins in Human Cervical Intraepithelial Kern F, Bernhardt J, Regenass S, Weller A, Buhler FR, Neoplasia and Invasive Carcinoma (October), 973 377 Hof PR: See Buee L, Hof PR, Roberts DD, Delacourte A, Hamilton SR: See Mulder JWR, Offerhaus GJA, de Morrison JH, Fillit HM, 783 Feyter EP, Floyd JJ, Kern SE, Vogelstein B, Hamilton Holley JA, Janssen YMW, Mossman BT, Taatjes DJ: SR, 797 Increased Manganese Superoxide Dismutase Protein Hanson CA: See Ross CW, Schlegelmilch JA, Grogan in Type II Epithelial Cells of Rat Lungs after Inhalation of TM, Weiss LM, Schnitzer B, Hanson CA, 457 Crocidolite Asbestos or Cristobalite Silica (August), Hantgan RR: See Hensler ME, Frojmovic M, Taylor RG, 475 Hantgan RR, Lewis JC, 707 Hornbuckle WE: See Peters DN, Steinberg H, Anderson Harkema JR, Hotchkiss JA: In Vivo Effects of Endo- WI, Hornbuckle WE, Cote PJ, Gerin JL, Lewis RM, Ten- toxin on lntraepithelial Mucosubstances in Rat Pulmo- nant BC, 143 nary Airways: Quantitative Histochemistry (August), Horn T: See Finzi E, Ho T, Anhalt G, Hawkins W, Harkins 307 R, Horn T, 643 Harkins R: See Finzi E, Ho T, Anhalt G, Hawkins W, Ho T: See Finzi E, Ho T, Anhalt G, Hawkins W, Harkins R, Harkins R, Horn T, 643 Horn T, 643 Hart MN, Fabry Z, Love-Homan L, Keiner J, Sade- Hotchkiss JA: See Harkema JR, Hotchkiss JA, 307 wasser KL, Moore SA: Brain Microvascular Smooth Hruban RH: See Wu TC, Lee WA, Pizzorno MC, Au WC, Muscle and Endothelial Cells Produce Granulocyte Chan YJ, Hruban RH, Hutchins GM, Hayward GS: Macrophage Colony-stimulating Factor and Support 1247 Colony Formation of Granulocyte-Macrophage-like Hsu PL: See Collins CL, Ordonez NG, Schaefer R, Cook Cells (August), 421 CD, Xie SS, Granger J, Hsu PL, Fink L, Hsu SM, 827 Hawes D: See Shibata D, Hawes D, Li ZH, Hernandez Hsu PL: See Hsu SM, Xie SS, Hsu PL, Waldron JA Jr, 129 AM, Spruck CH, Nichols PW, 539 Hsu SM, Xie SS, Waldron JA Jr: Functional Heteroge- Hawkins W: See Finzi E, Ho T, Anhalt G, Hawkins W, neity and Pathogenic Significance of Interleukin-6 in B- Harkins R, Horn T, 643 cell Lymphomas (October), 915 Hayden DW: See Johnson KH, Sletten K, Hayden DW, Hsu SM, Xie SS, Hsu PL, Waldron JA Jr: Interleukin-6, O'Brien TD, Roertgen KE, Westermark P: 1013 But Not lnterleukin-4, Is Expressed by Reed-Sternberg Hayward GS: See Wu TC, Lee WA, Pizzorno MC, Au Cells in Hodgkin's Disease with or without Histologic WC, Chan YJ, Hruban RH, Hutchins GM, Hayward GS: Features of Castleman's Disease (July), 129 1247 Hsu SM: See Collins CL, Ordonez NG, Schaefer R, Cook Hendrickx AG: See Miller CJ, Vogel P, Alexander NJ, CD, Xie SS, Granger J, Hsu PL, Fink L, Hsu SM, 827 Sutjipto S, Hendrickx AG, Marx PA, 655 Hsu SM: See Macon WR, Cousar JB, Waldron JA Jr, Hsu Hensler ME, Frojmovic M, Taylor RG, Hantgan RR, SM: 1031 Lewis JC: Platelet Morphologic Changes and Fibrino- Huang S, Paulauskis JD, Godleski JJ, Kobzik L: Ex- gen Receptor Localization: Initial Responses in ADP- pression of Macrophage Inflammatory Protein-2 and activated Human Platelets (September), 707 KC mRNA in Pulmonary Inflammation (October), 981 1536 Index of Authors AJP December 1992, Vol. 141, No. 6

Huber SA: See Frizelle S, Schwarz J, Huber SA, Leslie K, Recombinant Tumor Necrosis Factor in E. co/i-chal- 203 lenged Swine (November): 1197 Huettner PC, Weinberg DS, Lage JM: Assessment of Jevnikar AM, Singer GG, Brennan DC, Xu HW, Kel- Proliferative Activity in Ovarian Neoplasms by Flow and ley VR: Dexamethasone Prevents Autoimmune Static Cytometry: Correlation with Prognostic Features Nephritis and Reduces Renal Expression of la But Not (September), 699 Costimulatory Signals (September), 743 Huffnagle GB, Lipscomb MF: Animal Model of Human Jilek P: See Jonjic N, Marfin-Padura 1, Pollicino T, Berna- Disease: Pulmonary Cryptococcosis (December): C27 sconi S, Jilek P, Bigotti A, Mortarini R, Anichini A, Par- Hughes SS: See Crabb ID, Hughes SS, Hicks DG, Puzas miani G, Colotta F, Dejana E, Mantovani A, Natali PG: JE, Tsao GJY, Rosier RN, 579 1323 Hukkanen V: See Auvinen E, Kujari H, Arstila P, Huk- Jin L: See Lloyd RV, Jin L, Chang A, Kulig E, Camper SA, kanen V: 1217 Ross BD, Downs TR, Frohman LA, 895 Hutchins GM: See Wu TC, Lee WA, Pizzorno MC, Au Joffe B: See Sugiyama N, Marcovina S, Gown AM, Seftel WC, Chan YJ, Hruban RH, Hutchins GM, Hayward GS: H, Joffe B, Chait A, 99 1247 Johnson KH, Sletten K, Hayden DW, O'Brien TD, Roertgen KE, Westermark P: Pulmonary Vascular lida T: See Fung MA, Sato N, lida T, Fukuyama K, Ep- Amyloidosis in Aged Dogs: A New Form of Spontane- stein WL: 1445 ously Occurring Amyloidosis Derived from Apolipopro- Ii K, Kyle RA, Dyck PJ: Immunohistochemical Character- tein AL (November): 1013 ization of Amyloid Proteins in Sural Nerves and Clinical Johnson MD, Federspiel CF, Gold Li, Moses HL: Associations in Amyloid Neuropathy (July), 217 Transforming Growth Factor-fl and Transforming Ikeda M, Ikeda U, Ohara T, Kusano E, Kano S: Re- Growth Factor f-receptor Expression in Human Menin- combinant Interleukin-6 Inhibits the Growth of Rat Mes- gioma Cells (September), 633 angial Cells in Culture (August), 327 Johnson RC: See Defosse DL, Duray PH, Johnson RC, Ikeda U: See Ikeda M, Ikeda U, Ohara T, Kusano E, Kano 3 S, 327 Johnson RJ: See Lovett DH, Johnson RJ, Marti HP, Mar- Immonen 1: See Fuchs U, Kivela T, Summanen P, Im- tin J, Davies M, Couser WG, 85 monen 1, Tarkkanen A, 169 Jones CL, Buch S, Post M, McCulloch L, Liu E, Eddy Inoue A: See Sasaguri Y, Komiya S, Sugama K, Suzuki AA: Renal Extracellular Matrix Accumulation in Acute K, Inoue A, Morimatsu M, Nagase H, 611 Puromycin Aminonucleoside Nephrosis in Rats (De- lqbal K: See Wrzolek MA, Merz PA, Kascsak R, cember): 1381 Grundke-lqbal I, lqbal K, Rubenstein R, Tonna-DeMasi Jones R: Ultrastructural Analysis of Contractile Cell De- M, Goller NL, Mehta P, Wisniewski HM, 343 velopment in Lung Microvessels in Hyperoxic Pulmo- Isaacson PG, Androulakis-Papachristou A, Diss nary Hypertension (December): 1491 TC, Pan L, Wright DH: Follicular Colonization in Thy- Jonjic N, Martin-Padura 1, Pollicino T, Bernasconi S, roid Lymphoma (July), 43 Jilek P, Bigotti A, Mortarini R, Anichini A, Par- lsacchi A: See Gonzalez AM, Buscaglia M, Fox R, Isac- miani G, Colotta F, Dejana E, Mantovani A, Natali chi A, Sarmientos P, Farris J, Ong M, Martineau D, PG: Regulated Expression of Vascular Cell Adhesion Lappi DA, Baird A, 661 Molecule-1 in Human Malignant Melanoma (De- Isik FF, McDonald TO, Ferguson M, Yamanaka E, cember): 1323 Gordon D: Transplant Arteriosclerosis in a Rat Aortic Juusela H: See Korhonen M, Laitinen L, Ylanne J, Kou- Model (November): 1139 koulis GK, Quaranta V, Juusela H, Gould VE, Virtanen I: 1161 Jakobsen E: See Beiske K, Myklebust AT, Aamdal S, Langholm R, Jakobsen E, Fodstad 0, 531 Janssen YMW: See Holley JA, Janssen YMW, Moss- Kamel OW: See Gelb AB, Kamel OW, LeBrun DP, man BT, Taatjes DJ, 475 Warnke RA: 1453 Jeffery RE: See Poulsom R, Pignatelli M, Stetler-Steven- Kano S: See Ikeda M, Ikeda U, Ohara T, Kusano E, Kano son WG, Liotta LA, Wright PA, Jeffery RE, Longcroft S, 327 JM, Rogers L, Stamp GWH, 389 Kanwar YS: See Lelongt B, Kashihara N, Makino H, Kan- Jeon HJ: See Sarker AB, Akagi T, Jeon HJ, Miyake K, war YS, 561 Murakami I, Yoshino T, Takahashi K, Nose S, 19 Kaplan C: See Greco MA, Wieczorek R, Sachdev R, Ka- Jesmok G, Lindsey C, Duerr M, Fournel M, Emerson plan C, Nuovo GJ, Demopoulos RI, 835 T Jr: Efficacy of Monoclonal Antibody Against Human Kasahara K: See Strieter RM, Kasahara K, Allen RM, Index of Authors 1537 AJP December 1992, Vol. 141, No. 6

Standiford TJ, Rolfe MW, Becker FS, Chensue SW, Knowles DM: See Athan E, Chadburn A, Knowles DM, Kunkel SL, 397 193 Kascsak R: See Wrzolek MA, Merz PA, Kascsak R, Kobayashi Y: See Aster JC, Kobayashi Y, Shiota M, Mori Grundke-lqbal I, lqbal K, Rubenstein R, Tonna-DeMasi S, Sklar J, 291 M, Goller NL, Mehta P, Wisniewski HM, 343 Kobzik L: See Huang S, Paulauskis JD, Godleski JJ, Kashgarian M: See Ruef C, Kashgarian M, Coleman DL, Kobzik L, 981 429 Koch AE: See Strieter RM, Kunkel SL, Elner VM, Martonyi Kashihara N: See Lelongt B, Kashihara N, Makino H, CL, Koch AE, Polverini PJ, Elner SG: 1279 Kanwar YS, 561 Kodama T: See Naito M, Suzuki H, Mori T, Matsumoto A, Kasinath BS, Fried TA, Davalath S, Marsden PA: Kodama T, Takahashi K, 591 Glomerular Epithelial Cells Synthesize Endothelin Pep- Koeffler HP: See Said JW, Barrera R, Shintaku IP, Naka- tides (August), 279 mura H, Koeffler HP: 1343 Kattine AA: See Fuhr JE, Kattine AA, Sullivan TA, Nelson Komiya S: See Sasaguri Y, Komiya S, Sugama K, Suzuki HS Jr, 211 K, Inoue A, Morimatsu M, Nagase H, 611 Keiner J: See Hart MN, Fabry Z, Love-Homan L, Keiner Konishi N: See Ward JM, Stevens JL, Konishi N, Kurata J, Sadewasser KL, Moore SA, 421 Y, Uno H, Diwan BA, Ohmori T, 955 Kelley VR: See Jevnikar AM, Singer GG, Brennan DC, Konter U: See Sterry W, Mielke V, Konter U, Kellner 1, Xu HW, Kelley VR, 743 Boehncke WH, 855 Kellner 1: See Sterry W, Mielke V, Konter U, Kellner I, Koprowski H: See Rakowicz-Szulczynska EM, Ste- Boehncke WH, 855 plewski Z, Koprowski H, 937 Kennedy SL: See Tauber MG, Kennedy SL, Tureen JH, Koretz K: See Eichelmann A, Koretz K, Mechtersheimer Lowenstein DH, 53 G, MOller P, 729 Kerbel RS: Expression of Multi-cytokine Resistance and Korhonen M, Laitinen L, Ylanne J, Koukoulis GK, Multi-growth Factor Independence in Advanced Stage Quaranta V, Juusela H, Gould VE, Virtanen 1: Inte- Metastatic Cancer: Malignant Melanoma as a Para- grin Distributions in Renal Cell Carcinomas of Various digm (September), 519 Grades of Malignancy (November): 1 161 Kerjaschki D: See Kurihara H, Anderson JM, Kerjaschki Koronel R: See Della Torre G, Donghi R, de Campos D, Farquhar MG, 805 Lima PO, Pasquini G, Pilotti S, Koronel R, Pierotti MA, Kern F: See Mackie EJ, Scott-Burden T, Hahn AWA, De Palo G, Della Porta G, Rilke F: 1181 Kern F, Bernhardt J, Regenass S, Weller A, Buhler FR, Koukoulis GK: See Korhonen M, Laitinen L, Ylanne J, 377 Koukoulis GK, Quaranta V, Juusela H, Gould VE, Vir- Kern SE: See Mulder JWR, Offerhaus GJA, de Feyter EP, tanen 1:1161 Floyd JJ, Kern SE, Vogelstein B, Hamilton SR, 797 Koulos JP: See Hillemanns P, Tannous-Khuri L, Koulos Kirkpatrick CJ: See Offner FA, Wirtz HC, Schiefer J, JP, Talmage D, Wright TC Jr, 973 Bigalke I, Klosterhalfen B, Bittinger F, Mittermayer C, Kramps JA: See Rudolphus A, Stolk J, van Twisk C, van Kirkpatrick CJ, 601 Noorden CJF, Dijkman JH, Kramps JA, 153 Kissell-Rainville S: See Dvorak AM, Warner JA, Morgan Kudryk BJ: See Valenzuela R, Shainoff JR, DiBello PM, E, Kissell-Rainville S, Lichtenstein LM, MacGlashan DW Urbanic DA, Anderson JM, Matsueda GR, Kudryk BJ, Jr: 1309 861 Kitamoto T, Doh-ura K, Muramoto T, Miyazono M, Kuiper CM: See van Kalken CK, Giaccone G, van der Tateishi J: The Primary Structure of the Prion Protein Valk P, Kuiper CM, Hadisaputro MMN, Bosma SAA, Influences the Distribution of Abnormal Prion Protein in Scheper RJ, Meijer CJLM, Pinedo HM: 1063 the Central Nervous System (August), 271 Kujari H: See Auvinen E, Kujari H, Arstila P, Hukkanen V: Kivela T: See Fuchs U, Kivela T, Summanen P, Immonen 1217 I, Tarkkanen A, 169 Kulig E: See Lloyd RV, Jin L, Chang A, Kulig E, Camper Kjeldsberg CR: See Segal GH, Wittwer CT, Fishleder SA, Ross BD, Downs TR, Frohman LA, 895 AJ, Stoler MH, Tubbs RR, Kjeldsberg CR: 1291 Kunkel SL: See Strieter RM, Kasahara K, Allen RM, Stan- Kleinknecht C: See Dubrulle MP, Terzi F, Gubler MC, diford TJ, Rolfe MW, Becker FS, Chensue SW, Kunkel Kleinknecht C, Schaeverbeke M: 1481 SL, 397 Klemp KF: See Guyton JR, Klemp KF, 925 Kunkel SL: See Strieter RM, Kunkel SL, Elner VM, Mar- Klosterhalfen B: See Offner FA, Wirtz HC, Schiefer J, tonyi CL, Koch AE, Polverini PJ, Elner SG: 1279 Bigalke I, Klosterhalfen B, Bittinger F, Mittermayer C, Kurata Y: See Ward JM, Stevens JL, Konishi N, Kurata Y, Kirkpatrick CJ, 601 Uno H, Diwan BA, Ohmori T, 955 1538 Index of Authors AJP December 1992, Vol. 141, No. 6

Kurihara H, Anderson JM, Kerjaschki D, Farquhar Leslie K: See Frizelle S, Schwarz J, Huber SA, Leslie K, MG: The Altered Glomerular Filtration Slits Seen in Pur- 203 omycin Aminonucleoside Nephrosis and Protamine Levy RJ: See Webb CL, Nguyen NM, Schoen FJ, Levy Sulfate-treated Rats Contain the Tight Junction Protein RJ, 487 ZO-1 (October), 805 Lewis JC: See Hensler ME, Frojmovic M, Taylor RG, Kuriyama S: See Sakuda H, Nakashima Y, Kuriyama S, Hantgan RR, Lewis JC, 707 Sueishi K: 1507 Lewis RM: See Peters DN, Steinberg H, Anderson WI, Kusano E: See Ikeda M, Ikeda U, Ohara T, Kusano E, Hornbuckle WE, Cote PJ, Gerin JL, Lewis RM, Tennant Kano S, 327 BC, 143 Kyle RA: See Ii K, Kyle RA, Dyck PJ, 217 Lewis W: See Papoian T, Lewis W: 1187 Lichtenstein LM: See Dvorak AM, Warner JA, Morgan Lackner AA: See Sasseville VG, Newman WA, Lackner E, Kissell-Rainville S, Lichtenstein LM, MacGlashan DW AA, Smith MO, Lausen NCG, Beall D, Ringler D: 1013 Jr: 1309 Ladanyi A: See Timar J, Ladanyi A, Lapis K, Moczar M, Like AA: See Barlow AK, Like AA: 1043 467 Lindsey C: See Jesmok G, Lindsey C, Duerr M, Fournel Ladanyi M, Wang S, Niesvizky R, Feiner H, Michaeli M, Emerson T Jr: 1197 J: Proto-oncogene Analysis in Multiple Myeloma (Oc- Link M: See Smedts F, Ramaekers F, Troyanovsky S, tober), 949 Pruszczynski M, Link M, Lane B, Leigh I, Schijf C, Lage JM: See Huettner PC, Weinberg DS, Lage JM, 699 Vooijs P, 497 Lagrasta C: See Olivetti G, Quaini F, Lagrasta C, Ricci R, Linnala A: See Tiitta 0, Wahlstrom T, Paavonen J, Lin- Tiberti G, Capasso JM, Anversa P, 227 nala A, Sharma S, Gould VE, Virtanen I, 907 Laitinen L: See Korhonen M, Laitinen L, Ylanne J, Kou- Lin WC, Pretlow TP, Pretlow TG 11, Culp LA: High-re- koulis GK, Quaranta V, Juusela H, Gould VE, Virtanen I: solution Analyses of Two Different Classes of Tumor 1161 Cells In Situ Tagged with Alternative Histochemical Lane B: See Smedts F, Ramaekers F, Troyanovsky S, Marker Genes (December): 1331 Pruszczynski M, Link M, Lane B, Leigh I, Schijf C, Liotta LA: See Poulsom R, Pignatelli M, Stetler-Steven- Vooijs P, 497 son WG, Liotta LA, Wright PA, Jeffery RE, Longcroft Langholm R: See Beiske K, Myklebust AT, Aamdal S, JM, Rogers L, Stamp GWH, 389 Langholm R, Jakobsen E, Fodstad 0, 531 Lipscomb MF: See Huffnagle GB, Lipscomb MF: 1517 Lapis K: See Timar J, Ladanyi A, Lapis K, Moczar M, 467. Liu E: See Jones CL, Buch S, Post M, McCulloch L, Liu E, Lappi DA: See Gonzalez AM, Buscaglia M, Fox R, Isac- Eddy AA: 1381 chi A, Sarmientos P, Farris J, Ong M, Martineau D, Li ZH: See Shibata D, Hawes D, Li ZH, Hernandez AM, Lappi DA, Baird A, 661 Spruck CH, Nichols PW, 539 Lausen NCG: See Sasseville VG, Newman WA, Lackner Llorens A: See Tarr6s MC, Martinez SM, Montenegro S, AA, Smith MO, Lausen NCG, Beall D, Ringler D: 1021 Llorens A, Picena JC, Naves A, 761 LeBrun DP: See Gelb AB, Kamel OW, LeBrun DP, Lloyd RV, Jin L, Chang A, Kulig E, Camper SA, Ross Warnke RA: 1453 BD, Downs TR, Frohman LA: Morphologic Effects of Lee CY: See Ross JS, Bui HX, del Rosario A, Sonbati H, hGRH Gene Expression on the Pituitary, Liver, and Pan- George M, Lee CY, 721 creas of MT-hGRH Transgenic Mice: An In Situ Hybrid- Lee NC: See Munro JM, Lo SK, Corless C, Robertson ization Analysis (October), 895 MJ, Lee NC, Barnhill RL, Weinberg DS, Bevilacqua MP: Lo D, Quill H, Burkly L, Scott B, Palmiter RD, Brin- 1397 ster RL: A Recessive Defect in Lymphocyte or Granu- Lee WA: See Wu TC, Lee WA, Pizzorno MC, Au WC, locyte Function Caused by an Integrated Transgene Chan YJ, Hruban RH, Hutchins GM, Hayward GS: (November): 1237 1247 Longcroft JM: See Poulsom R, Pignatelli M, Stetler-Ste- Leigh 1: See Smedts F, Ramaekers F, Troyanovsky S, venson WG, Liotta LA, Wright PA, Jeffery RE, Long- Pruszczynski M, Link M, Lane B, Leigh I, Schijf C, croft JM, Rogers L, Stamp GWH, 389 Vooijs P, 497 Lopes MBS: See Gonzalez-Fernandez F, Lopes MBS, Lelongt B, Kashihara N, Makino H, Kanwar YS: Influ- Garcia-Fernandez JM, Foster RG, De Grip WJ, Rosem- ence of Genetics on the Nephritogenic Potential of Pro- berg S, Newman SA, VandenBerg SR, 363 teoglycans (September), 561 Lopes MBS: See Wolf BB, Lopes MBS, VandenBerg SR, Lemere CA: See Yamaguchi H, Yamazaki T, Lemere Gonias SL, 37 CA, Frosch MP, Selkoe DJ, 249 Lo SK: See Munro JM, Lo SK, Corless C, Robertson MJ, Index of Authors 1539 AJP December 1992, Vol. 141, No. 6

Lee NC, Barnhill RL, Weinberg DS, Bevilacqua MP: Isacchi A, Sarmientos P, Farris J, Ong M, Martineau D, 1397 Lappi DA, Baird A, 661 Louis DN, von Deimling A, Seizinger BR: A (CA), Di- Martinez SM: See Tarr6s MC, Martinez SM, Montenegro nucleotide Repeat Assay for Evaluating Loss of Allelic S, Llorens A, Picena JC, Naves A, 761 Heterozygosity in Small and Archival Human Brain Tu- Martin J: See Lovett DH, Johnson RJ, Marti HP, Martin J, mor Specimens (October), 777 Davies M, Couser WG, 85 Love-Homan L: See Hart MN, Fabry Z, Love-Homan L, Martin LJ: See Price DL, Walker LC, Martin LJ, Sisodia Keiner J, Sadewasser KL, Moore SA, 421 SS, 767 Lovett DH, Johnson RJ, Marti HP, Martin J, Davies Martin-Padura 1: See Jonjic N, Martin-Padura I, Pollicino M, Couser WG: Structural Characterization of the Mes- T, Bernasconi S, Jilek P, Bigotti A, Mortarini R, Anichini angial Cell Type IV Collagenase and Enhanced Expres- A, Parmiani G, Colotta F, Dejana E, Mantovani A, Natali sion in a Model of Immune Complex-mediated Glomeru- PG: 1323 lonephritis (July), 85 Martonyi CL: See Strieter RM, Kunkel SL, Elner VM, Mar- Lowenstein DH: See Tauber MG, Kennedy SL, Tureen tonyi CL, Koch AE, Polverini PJ, Elner SG: 1279 JH, Lowenstein DH, 53 Marx PA: See Miller CJ, Vogel P, Alexander NJ, Sutjipto Lowery DE: See Murphy GM Jr, Greenberg BD, Ellis S, Hendrickx AG, Marx PA, 655 WG, Forno LS, Salamat SM, Gonzalez-DeWhitt PA, Lo- Matsueda GR: See Valenzuela R, Shainoff JR, DiBello wery DE, Tinklenberg JR, Eng LF, 357 PM, Urbanic DA, Anderson JM, Matsueda GR, Kudryk Lowes AP: See Williams ED, Lowes AP, Williams D, Wil- BJ, 861 liams GT, 773 Matsumoto A: See Naito M, Suzuki H, Mori T, Matsu- Lugo J: See Shea CR, McNutt NS, Volkenandt M, Lugo moto A, Kodama T, Takahashi K, 591 JI, Prioleau PG, Albino AP, 25 McCollum CN: See Herrick SE, Sloan P, McGurk M, Freak L, McCollum CN, Ferguson MWJ: 1085 Macchiarini P: See Fontanini G, Pingitore R, Bigini D, McConahey PJ: See Duchosal MA, Eming SA, McCona- Vignati S, Pepe S, Ruggiero A, Macchiarini P: 1285 hey PJ, Dixon FJ: 1097 MacGlashan DW Jr: See Dvorak AM, Warner JA, Mor- McCulloch L: See Jones CL, Buch S, Post M, McCulloch gan E, Kissell-Rainville S, Lichtenstein LM, MacGla- L, Liu E, Eddy AA: 1381 shan DW Jr: 1309 McDonald TO: See Isik FF, McDonald TO, Ferguson M, Mackie EJ, Scott-Burden T, Hahn AWA, Kern F, Yamanaka E, Gordon D: 1 139 Bernhardt J, Regenass S, Weller A, BUhler FR: McGurk M: See Herrick SE, Sloan P, McGurk M, Freak L, Expression of Tenascin by Vascular Smooth Muscle McCollum CN, Ferguson MWJ: 1085 Cells: Alterations in Hypertensive Rats and Stimulation McNeil PL: See Yu QC, McNeil PL: 1349 by Angiotensin II (August), 377 McNutt NS: See Shea CR, McNutt NS, Volkenandt M, Macon WR, Cousar JB, Waldron JA Jr, Hsu SM: In- Lugo J, Prioleau PG, Albino AP, 25 terleukin-4 May Contribute to the Abundant T-cell Reac- Mechtersheimer G: See Eichelmann A, Koretz K, tion and Paucity of Neoplastic B Cells in T-cell-Rich Mechtersheimer G, Moller P, 729 B-cell Lymphomas (November): 1031 Medcalf R: See Hagege J, Peraldi MN, Rondeau E, Maeda S: See Murakami T, Yi S, Maeda S, Tashiro F, Adida C, Delarue F, Medcalf R, Schleuning WD, Sraer Yamamura KI, Takahashi K, Shimada K, Araki S, 451 JD, 117 Mair S: See Dinges HP, Zatloukal K, Denk H, Smolle J, Mehta P: See Wrzolek MA, Merz PA, Kascsak R, Mair S, 69 Grundke-lqbal I, Iqbal K, Rubenstein R, Tonna-DeMasi Makino H: See Lelongt B, Kashihara N, Makino H, Kan- M, Goller NL, Mehta P, Wisniewski HM, 343 war YS, 561 Meijer CJLM: See van Kalken CK, Giaccone G, van der Mantovani A: See Jonjic N, Martin-Padura I, Pollicino T, Valk P, Kuiper CM, Hadisaputro MMN, Bosma SAA, Bernasconi S, Jilek P, Bigotti A, Mortarini R, Anichini A, Scheper RJ, Meijer CJLM, Pinedo HM: 1063 Parmiani G, Colotta F, Dejana E, Mantovani A, Natali Merz PA: See Wrzolek MA, Merz PA, Kascsak R, PG: 1323 Grundke-lqbal I, Iqbal K, Rubenstein R, Tonna-DeMasi Marcovina S: See Sugiyama N, Marcovina S, Gown AM, M, Goller NL, Mehta P, Wisniewski HM, 343 Seftel H, Joffe B, Chait A, 99 Meyling FHJG: See Parmentier HK, van Wichen DF, Marsden PA: See Kasinath BS, Fried TA, Davalath S, Meyling FHJG, Gouldsmit J, Schuurman HJ: 1209 Marsden PA, 279 Michaeli J: See Ladanyi M, Wang S, Niesvizky R, Feiner Marti HP: See Lovett DH, Johnson RJ, Marti HP, Martin J, H, Michaeli J, 949 Davies M, Couser WG, 85 Mielke V: See Sterry W, Mielke V, Konter U, Kellner 1, Martineau D: See Gonzalez AM, Buscaglia M, Fox R, Boehncke WH, 855 1540 Index of Authors AJP December 1992, Vol. 141, No. 6

Miller CJ, Vogel P, Alexander NJ, Sutjipto S, Hen- lar Genetic Alterations in the Adenoma-Carcinoma Se- drickx AG, Marx PA: Localization of SIV in the Genital quence of the Large Bowel (October), 797 Tract of Chronically Infected Female Rhesus Maca- Mufloz-Gomez J: See Campistol JM, Sol6 M, Bombi JA, ques (September), 655 Rodriguez R, Mirapeix E, Muroz-Gomez J, Revert OW, Mirapeix E: See Campistol JM, Sol6 M, Bombi JA, Rodri- 241 guez R, Mirapeix E, Munoz-Gomez J, Revert OW, 241 Munro JM, Lo SK, Corless C, Robertson MJ, Lee Mittermayer C: See Offner FA, Wirtz HC, Schiefer J, NC, Barnhill RL, Weinberg DS, Bevilacqua MP: Ex- Bigalke I, Klosterhalfen B, Bittinger F, Mittermayer C, pression of Sialyl-Lewis X, an E-Selectin Ligand, in In- Kirkpatrick CJ, 601 flammation, Immune Processes, and Lymphoid Tis- Miyake K: See Sarker AB, Akagi T, Jeon HJ, Miyake K, sues (December): 1397 Murakami 1, Yoshino T, Takahashi K, Nose S, 19 Murakami 1: See Sarker AB, Akagi T, Jeon HJ, Miyake K, Miyazono M: See Kitamoto T, Doh-ura K, Muramoto T, Murakami I, Yoshino T, Takahashi K, Nose S, 19 Miyazono M, Tateishi J, 271 Murakami T, Yi S, Maeda S, Tashiro F, Yamamura Moczar M: See Timar J, Ladanyi A, Lapis K, Moczar M, KI, Takahashi K, Shimada K, Araki S: Effect of 467 Serum Amyloid P Component Level on Transthyretin- Moller P: See Eichelmann A, Koretz K, Mechtersheimer derived Amyloid Deposition in a Transgenic Mouse G, Moller P, 729 Model of Familial Amyloidotic Polyneuropathy (Au- Monteagudo C: See Campo E, Monteagudo C, Castron- gust), 451 ovo V, Claysmith AP, Fernandez PL, Sobel ME: 1073 Muramoto T: See Kitamoto T, Doh-ura K, Muramoto T, Montenegre S: See Tarr6s MC, Martinez SM, Montene- Miyazono M, Tateishi J, 271 gro S, Llorens A, Picena JC, Naves A, 761 Murphy GM Jr, Greenberg BD, Ellis WG, Forno LS, Moore SA: See Hart MN, Fabry Z, Love-Homan L, Keiner Salamat SM, Gonzalez-DeWhitt PA, Lowery DE, J, Sadewasser KL, Moore SA, 421 Tinklenberg JR, Eng LF: Alzheimer's Disease: ,B- Morales C: See Vaquero J, Zurita M, Oya S, Arias A, amyloid Precursor Protein Expression in the Nucleus Moreno M, Morales C: 1037 Basalis of Meynert (August), 357 Moreno M: See Vaquero J, Zurita M, Oya S, Arias A, Mykiebust AT: See Beiske K, Myklebust AT, Aamdal S, Moreno M, Morales C: 1037 Langholm R, Jakobsen E, Fodstad 0, 531 Morgan E: See Dvorak AM, Warner JA, Morgan E, Kis- sell-Rainville S, Lichtenstein LM, MacGlashan DW Jr: Nagase H: See Sasaguri Y, Komiya S, Sugama K, Suzuki 1309 K, Inoue A, Morimatsu M, Nagase H, 611 Morgello S: Epstein-Barr and Human Immunodeficiency Nagura H: See Sasano H, Goukon Y, Nishihira T, Nagura Viruses in Acquired Immunodeficiency Syndrome-re- H, 545 lated Primary Central Nervous System Lymphoma (Au- Naito M, Suzuki H, Mori T, Matsumoto A, Kodama T, gust), 441 Takahashi K: Coexpression of Type and Type 11 Hu- Morimatsu M: See Sasaguri Y, Komiya S, Sugama K, man Macrophage Scavenger Receptors in Macro- in Athero- Suzuki K, Inoue A, Morimatsu M, Nagase H, 611 phages of Various Organs and Foam Cells sclerotic Lesions (September), 591 Mori S: See Aster JC, Kobayashi Y, Shiota M, Mori S, Nakamura H: See Said JW, Barrera R, Shintaku IP, Naka- Sklar J, 291 mura H, Koeffler HP: 1343 Mori T: See Naito M, Suzuki H, Mori T, Matsumoto A, Nakashima Y: See Sakuda H, Nakashima Y, Kuriyama 591 Kodama T, Takahashi K, S, Sueishi K: 1507 Morrison JH: See Bu6e L, Hof PR, Roberts DD, Dela- Natali PG: See Jonjic N, Martin-Padura 1, Pollicino T, Ber- courte A, Morrison JH, Fillit HM, 783 nasconi S, Jilek P, Bigotti A, Mortarini R, Anichini A, Mortarini R: See Jonjic N, Martin-Padura 1, Pollicino T, Parmiani G, Colotta F, Dejana E, Mantovani A, Natali Bernasconi S, Jilek P, Bigotti A, Mortarini R, Anichini A, PG: 1323 Parmiani G, Colotta F, Dejana E, Mantovani A, Natali Naves A: See Tarres MC, Martinez SM, Montenegro S, PG: 1323 Llorens A, Picena JC, Naves A, 761 Moses HL: See Johnson MD, Federspiel CF, Gold LI, Nelson HS Jr: See Fuhr JE, Kattine AA, Sullivan TA, Nel- Moses HL, 633 son HS Jr, 211 Mossman BT: See Holley JA, Janssen YMW, Mossman Newman SA: See Gonzalez-Fernandez F, Lopes MBS, BT, Taatjes DJ, 475 Garcia-Fernandez JM, Foster RG, De Grip WJ, Rosem- Mulder JWR, Offerhaus GJA, de Feyter EP, Floyd berg S, Newman SA, VandenBerg SR, 363 JJ, Kern SE, Vogelstein B, Hamilton SR: The Rela- Newman WA: See Sasseville VG, Newman WA, Lackner tionship of Quantitative Nuclear Morphology to Molecu- AA, Smith MO, Lausen NCG, Beall D, Ringler D: 1021 Index of Authors 1541 AJP December 1992, Vol. 141, No. 6

Nguyen NM: See Webb CL, Nguyen NM, Schoen FJ, Oya S: See Vaquero J, Zurita M, Oya S, Arias A, Moreno Levy RJ, 487 M, Morales C: 1037 Nichols PW: See Shibata D, Hawes D, Li ZH, Hernandez AM, Spruck CH, Nichols PW, 539 Paavonen J: See Tiitta 0, Wahlstrom T, Paavonen J, Nickoloff BJ: See Fivenson DP, Douglass MC, Nickoloff Linnala A, Sharma S, Gould VE, Virtanen I, 907 BJ: 1373 Paavonen T, Renkonen R: Selective Expression of Sia- Niesvizky R: See Ladanyi M, Wang S, Niesvizky R, lyl-Lewis X and Lewis A Epitopes, Putative Ligands for Feiner H, Michaeli J, 949 L-selectin, on Peripheral Lymph-node High Endothelial Nieto R: See Yang GCH, Nieto R, Stachura I, Gallo GR, Venules (December): 1259 409 Page C, Rose M, Yacoub M, Pigott R: Antigenic Heter- Nishihira T: See Sasano H, Goukon Y, Nishihira T, Na- ogeneity of Vascular Endothelium (September), 673 gura H, 545 Page DL: See Simpson JF, Page DL, 285 Niwa H: See Takeuchi A, Yoshizawa N, Yamamoto M, Palmiter RD: See Lo D, Quill H, Burkly L, Scott B, Pal- Sawasaki Y, Oda T, Senoo A, Niwa H, Fuse Y, 107 miter RD, Brinster RL: 1237 Nose S: See Sarker AB, Akagi T, Jeon HJ, Miyake K, Pan L: See Isaacson PG, Androulakis-Papachristou A, Murakami I, Yoshino T, Takahashi K, Nose S, 19 Diss TC, Pan L, Wright DH, 43 Nuovo GJ: See Greco MA, Wieczorek R, Sachdev R, Papoian T, Lewis W: Anthracyclines Selectively De- Kaplan C, Nuovo GJ, Demopoulos RI, 835 crease a Cardiac Actin mRNA Abundance in the Rat Heart (November): 1187 Pappolla MA, Omar RA, Sambamurti O'Brien TD: See Johnson KH, Sletten K, Hayden DW, K, Anderson O'Brien TD, Roertgen KE, Westermark P: 1013 JP, Robakis NK: The Genesis of the Senile Plaque: Oda T: See Takeuchi A, Yoshizawa N, Yamamoto M, Further Evidence in Support of its Neuronal Origin (No- Sawasaki Y, Oda T, Senoo A, Niwa H, Fuse Y, 107 vember): 1151 Offerhaus GJA: See Mulder JWR, Offerhaus GJA, de Parmentier HK, van Wichen DF, Meyling FHJG, Feyter EP, Floyd JJ, Kern SE, Vogelstein B, Hamilton Gouldsmit J, Schuurman HJ: Epitopes of Human Im- SR, 797 munodeficiency Virus Regulatory Proteins tat, nef, and Offner FA, Wirtz HC, Schiefer J, Bigalke 1, Kloster- rev Are Expressed in Normal Human Tissue (No- halfen B, Bittinger F, Mittermayer C, Kirkpatrick vember): 1209 CJ: Interaction of Human Malignant Melanoma (ST-ML- Parmiani G: See Jonjic N, Martin-Padura 1, Pollicino T, 12) Tumor Spheroids with Endothelial Cell Monolayers: Bernasconi S, Jilek P, Bigotti A, Mortarini R, Anichini A, Damage to Endothelium by Oxygen-derived Free Radi- Parmiani G, Colotta F, Dejana E, Mantovani A, Natali cals (September), 601 PG: 1323 Ohara T: See Ikeda M, Ikeda U, Ohara T, Kusano E, Kano Pasquini G: See Della Torre G, Donghi R, de Campos S, 327 Lima PO, Pasquini G, Pilotti S, Koronel R, Pierotti MA, De Palo G, Della Porta G, Rilke F: 1 181 Ohmori T: See Ward JM, Stevens JL, Konishi N, Kurata Paulauskis JD: See Huang Paulauskis Y, Uno H, Diwan BA, Ohmori T, 955 S, JD, Godleski JJ, Kobzik L, 981 Olivetti G, Quaini F, Lagrasta C, Ricci R, Tiberti G, Pearson JD: See Savage COS, Pottinger BE, Gaskin G, Capasso JM, Anversa P: Myocyte Cellular Hyper- Pusey CD, Pearson JD, 335 trophy and Hyperplasia Contribute to Ventricular Wall Penneys NS, Bogaert M, Serfling U, Sisto M: PCNA Remodeling in Anemia-induced Cardiac Hypertrophy Expression in Cutaneous Keratinous in Rats (July), 227 Neoplasms and Verruca Vulgaris (July), 139 Omar RA: See Omar Sambamurti Pappolla MA, RA, K, Pepe S: See Fontanini G, Pingitore R, Bigini D, Vignati S, Anderson JP, Robakis NK: 1151 Pepe S, Ruggiero A, Macchiarini P: 1285 Ong M: See Gonzalez AM, Buscaglia M, Fox R, Isacchi Peraldi MN: See Hagege J, Peraldi MN, Rondeau E, A, Sarmientos P, Farris J, Ong M, Martineau D, Lappi Adida C, Delarue F, Medcalf R, Schleuning WD, Sraer DA, Baird A, 661 JD, 117 Ordonez NG: See Collins CL, Ordonez NG, Schaefer R, Peters DN, Steinberg H, Anderson WI, Hornbuckle Cook CD, Xie SS, Granger J, Hsu PL, Fink L, Hsu SM, WE, Cote PJ, Gerin JL, Lewis RM, Tennant BC: 827 Immunopathology of Glomerulonephritis Associated Osborne-Pellegrin M: See Coutard M, Osborne-Pelle- with Chronic Woodchuck Hepatitis Virus Infection in grin M: 1053 Woodchucks (Marmota monax) (July), 143 Osborn M: See Domagala W, Striker G, Szadowska A, Picena JC: See Tarr6s MC, Martinez SM, Montenegro S, Dukowicz A, Weber K, Osborn M: 1003 Llorens A, Picena JC, Naves A, 761 1542 Index of Authors AJP December 1992, Vol. 141, No. 6

Pierotti MA: See Della Torre G, Donghi R, de Campos Quaini F: See Olivetti G, Quaini F, Lagrasta C, Ricci R, Lima PO, Pasquini G, Pilotti S, Koronel R, Pierotti MA, Tiberti G, Capasso JM, Anversa P, 227 De Palo G, Della Porta G, Rilke F: 1 181 Quaranta V: See Korhonen M, Laitinen L, Ylanne J, Kou- Pignatelli M: See Poulsom R, Pignatelli M, Stetler-Ste- koulis GK, Quaranta V, Juusela H, Gould VE, Virtanen I: venson WG, Liotta LA, Wright PA, Jeffery RE, Long- 1161 croft JM, Rogers L, Stamp GWH, 389 Quill H: See Lo D, Quill H, Burkly L, Scott B, Palmiter RD, Pigott R: See Page C, Rose M, Yacoub M, Pigott R, 673 Brinster RL: 1237 Pilotti S: See Della Torre G, Donghi R, de Campos Lima PO, Pasquini G, Pilotti S, Koronel R, Pierotti MA, De Radaszkiewicz T: See Chott A, Dragosics B, Radasz- Palo G, Della Porta G, Rilke F: 1181 kiewicz T: 1361 Pinedo HM: See van Kalken CK, Giaccone G, van der Rakowicz-Szulczynska EM, Steplewski Z, Ko- Valk P, Kuiper CM, Hadisaputro MMN, Bosma SAA, prowski H: Nuclear Translocation of Monoclonal Anti- Scheper RJ, Meijer CJLM, Pinedo HM: 1063 body Directed Against Cell-surface Carbohydrate Y De- Pingitore R: See Fontanini G, Pingitore R, Bigini D, Vig- terminant (October), 937 nati S, Pepe S, Ruggiero A, Macchiarini P: 1285 Ramaekers F: See Smedts F, Ramaekers F, Troyan- Pizzorno MC: See Wu TC, Lee WA, Pizzorno MC, Au ovsky S, Pruszczynski M, Link M, Lane B, Leigh I, Schijf WC, Chan YJ, Hruban RH, Hutchins GM, Hayward GS: C, Vooijs P, 497 1247 Regenass S: See Mackie EJ, Scott-Burden T, Hahn Pollicino T: See Jonjic N, Martin-Padura I, Pollicino T, AWA, Kern F, Bernhardt J, Regenass S, Weller A, Bernasconi S, Jilek P, Bigotti A, Mortarini R, Anichini A, BOhler FR, 377 Parmiani G, Colotta F, Dejana E, Mantovani A, Natali Renkonen R: See Paavonen T, Renkonen R: 1259 PG: 1323 Revert OW: See Campistol JM, Sole M, Bombi JA, Rodri- Polverini PJ: See Strieter RM, Kunkel SL, Elner VM, Mar- guez R, Mirapeix E, Muioz-Gomez J, Revert OW, 241 tonyi CL, Koch AE, Polverini PJ, Elner SG: 1279 Ricci R: See Olivetti G, Quaini F, Lagrasta C, Ricci R, Posner JB: See Dalmau J, Furneaux HM, Cordon-Cardo Tiberti G, Capasso JM, Anversa P, 227 C, Posner JB, 881 Rilke F: See Della Torre G, Donghi R, de Campos Lima Post M: See Jones CL, Buch S, Post M, McCulloch L, Liu PO, Pasquini G, Pilotti S, Koronel R, Pierotti MA, De E, Eddy AA: 1381 Palo G, Della Porta G, Rilke F: 1181 Pottinger BE: See Savage COS, Pottinger BE, Gaskin G, Ringler D: See Sasseville VG, Newman WA, Lackner AA, Pusey CD, Pearson JD, 335 Smith MO, Lausen NCG, Beall D, Ringler D: 1021 Poulsom R, Pignatelli M, Stetler-Stevenson WG, Robakis NK: See Pappolla MA, Omar RA, Sambamurti Liotta LA, Wright PA, Jeffery RE, Longcroft JM, K, Anderson JP, Robakis NK: 1151 Rogers L, Stamp GWH: Stromal Expression of 72 Roberts DD: See Bu6e L, Hof PR, Roberts DD, Dela- kda Type IV Collagenase (MMP-2) and TIMP-2 mRNAs courte A, Morrison JH, Fillit HM, 783 in Colorectal Neoplasia (August), 389 Robertson MJ: See Munro JM, Lo SK, Corless C, Robert- Pretlow TG 11: See Lin WC, Pretlow TP, Pretlow TG II, son MJ, Lee NC, Barnhill RL, Weinberg DS, Bevilacqua Culp LA: 1331 MP: 1397 Pretlow TP: See Lin WC, Pretlow TP, Pretlow TG II, Culp Rodriguez R: See Campistol JM, Sol6 M, Bombi JA, LA: 1331 Rodriguez R, Mirapeix E, Munoz-Gomez J, Revert OW, Price DL, Walker LC, Martin LJ, Sisodia SS: Amyloid- 241 and Alzheimer's Disease (October), 767 osis in Aging Roertgen KE: See Johnson KH, Sletten K, Hayden DW, RD, Price JE, Fujimaki T, Bucana Price JE: See Zhang O'Brien TD, Roertgen KE, Westermark P: 1013 Fidler IJ: 1 1 15 CD, Stetler-Steven- Prieditis H: See Adamson IYR, Prieditis H, Bowden DH, Rogers L: See Poulsom R, Pignatelli M, 319 son WG, Liotta LA, Wright PA, Jeffery RE, Longcroft 389 Prioleau PG: See Shea CR, McNutt NS, Volkenandt M, JM, Rogers L, Stamp GWH, Lugo J, Prioleau PG, Albino AP, 25 Rolfe MW: See Strieter RM, Kasahara K, Allen RM, Stan- Pruszczynski M: See Smedts F, Ramaekers F, Troyan- diford TJ, Rolfe MW, Becker FS, Chensue SW, Kunkel ovsky S, Pruszczynski M, Link M, Lane B, Leigh I, Schijf SL, 397 C, Vooijs P, 497 Rondeau E: See Hagege J, Peraldi MN, Rondeau E, Pusey CD: See Savage COS, Pottinger BE, Gaskin G, Adida C, Delarue F, Medcalf R, Schleuning WD, Sraer Pusey CD, Pearson JD, 335 JD, 117 Puzas JE: See Crabb ID, Hughes SS, Hicks DG, Puzas Rose M: See Page C, Rose M, Yacoub M, Pigott R, 673 JE, Tsao GJY, Rosier RN, 579 Rosemberg S: See Gonzalez-Fernandez F, Lopes MBS, Index of Authors 1543 AJP December 1992, Vol. 141, No. 6

Garcia-Fernandez JM, Foster RG, De Grip WJ, Rosem- Salvi R: See Alpini G, Aragona E, Dabeva M, Salvi R, berg S, Newman SA, VandenBerg SR, 363 Shafritz DA, Tavoloni N, 623 Rosier RN: See Crabb ID, Hughes SS, Hicks DG, Puzas Sambamurti K: See Pappolla MA, Omar RA, Samba- JE, Tsao GJY, Rosier RN, 579 murti K, Anderson JP, Robakis NK: 1151 Ross BD: See Lloyd RV, Jin L, Chang A, Kulig E, Camper Sanchez R: See Bucana CD, Fabra A, Sanchez R, Fidler SA, Ross BD, Downs TR, Frohman LA, 895 IJ: 1225 Ross CW, Schlegelmilch JA, Grogan TM, Weiss LM, Sarker AB, Akagi T, Jeon HJ, Miyake K, Murakami 1, Schnitzer B, Hanson CA: Detection of Epstein-Barr Yoshino T, Takahashi K, Nose S: Bauhinia Pur- Virus Genome in Ki-1 (CD30)-positive, Large-cell Ana- purea-A New Paraffin Section Marker for Reed-Stern- plastic Lymphomas Using the Polymerase Chain Reac- berg Cells of Hodgkin's Disease: A Comparison with tion (August), 457 Leu-M1 (CD15), LN2 (CD74), Peanut Agglutinin, and Rossi MA: Chronic Hemodynamic Unloading Regulates Ber-H2 (CD30) (July), 19 the Morphologic Development of Newborn Mouse Sarmientos P: See Gonzalez AM, Buscaglia M, Fox R, Hearts Transplanted into the Ear of Isogenic Adult Mice lsacchi A, Sarmientos P, Farris J, Ong M, Martineau D, (July), 183 Lappi DA, Baird A, 661 Ross JS, Bui HX, del Rosario A, Sonbati H, George Sasaguri Y, Komiya S, Sugama K, Suzuki K, Inoue M, Lee CY: Helicobacter pylori: Its Role in the Patho- A, Morimatsu M, Nagase H: Production of Matrix genesis of Peptic Ulcer Disease in a New Animal Model Metalloproteinases 2 and 3 (Stromelysin) by Stromal (September), 721 Cells of Giant Cell Tumor of Bone (September), 611 Rubenstein R: See Wrzolek MA, Merz PA, Kascsak R, Sasano H, Goukon Y, Nishihira T, Nagura H: In Situ Grundke-lqbal I, lqbal K, Rubenstein R, Tonna-DeMasi Hybridization and Immunohistochemistry of p53 Tumor M, Goller NL, Mehta P, Wisniewski HM, 343 Suppressor Gene in Human Esophageal Carcinoma Rudolphus A, Stolk J, van Twisk C, van Noorden (September), 545 CJF, Dijkman JH, Kramps JA: Detection of Extracel- Sasseville VG, Newman WA, Lackner AA, Smith lular Neutrophil Elastase in Hamster Lungs After Intra- MO, Lausen NCG, Beall D, Ringler D: Elevated Vas- tracheal Instillation of E. Coli Lipopolysaccharide Using cular Cell Adhesion Molecule-1 in AIDS Encephalitis In- a Fluorogenic, Elastase-specific, Synthetic Substrate duced by Simian Immunodeficiency Virus (November): (July), 153 1021 Ruef C, Kashgarian M, Coleman DL: Mesangial Cell- Sato N: See Fung MA, Sato N, lida T, Fukuyama K, Ep- matrix Interactions: Effects on Mesangial Cell Growth stein WL: 1445 and Cytokine Secretion (August), 429 Savage COS, Pottinger BE, Gaskin G, Pusey CD, Ruggiero A: See Fontanini G, Pingitore R, Bigini D, Vig- Pearson JD: Autoantibodies Developing to Myloper- nati S, Pepe S, Ruggiero A, Macchiarini P: 1285 oxidase and Proteinase 3 in Systemic Vasculitis Stimu- late Neutrophil Cytotoxicity Toward Cultured Endothe- Sachdev R: See Greco MA, Wieczorek R, Sachdev R, lial Cells (August), 335 Kaplan C, Nuovo GJ, Demopoulos RI, 835 Sawasaki Y: See Takeuchi A, Yoshizawa N, Yamamoto Sack GH Jr, Zink MC: Serum Amyloid A Gene Tran- M, Sawasaki Y, Oda T, Senoo A, Niwa H, Fuse Y, 107 scription in Synovial Cells During Retroviral Arthritis (September), 525 Schaefer R: See Collins CL, Ordonez NG, Schaefer R, Sadewasser KL: See Hart MN, Fabry Z, Love-Homan L, Cook CD, Xie SS, Granger J, Hsu PL, Fink L, Hsu SM, Keiner J, Sadewasser KL, Moore SA, 421 827 Said JW, Barrera R, Shintaku IP, Nakamura H, Schaeverbeke M: See Dubrulle MP, Terzi F, Gubler MC, Koeffler HP: Immunohistochemical Analysis of p53 Kleinknecht C, Schaeverbeke M: 1481 Expression in Malignant Lymphomas (December): Scheper RJ: See van Kalken CK, Giaccone G, van der 1343 Valk P, Kuiper CM, Hadisaputro MMN, Bosma SAA, Sakr WA: See Coltrera MD, Zarbo RJ, Sakr WA, Gown Scheper RJ, Meijer CJLM, Pinedo HM: 1063 AM, 817 Schiefer J: See Offner FA, Wirtz HC, Schiefer J, Bigalke Sakuda H, Nakashima Y, Kuriyama S, Sueishi K: Me- I, Klosterhalfen B, Bittinger F, Mittermayer C, Kirkpa- dia Conditioned by Smooth Muscle Cells Cultured in a trick CJ, 601 Variety of Hypoxic Environments Stimulates In Vitro Schijf C: See Smedts F, Ramaekers F, Troyanovsky S, Angiogenesis (December): 1507 Pruszczynski M, Link M, Lane B, Leigh I, Schijf C, Salamat SM: See Murphy GM Jr, Greenberg BD, Ellis Vooijs P, 497 WG, Forno LS, Salamat SM, Gonzalez-DeWhitt PA, Lo- Schlegelmilch JA: See Ross CW, Schlegelmilch JA, wery DE, Tinklenberg JR, Eng LF, 357 Grogan TM, Weiss LM, Schnitzer B, Hanson CA, 457 1544 Index of Authors AJP December 1992, Vol. 141, No. 6

Schieuning WD: See Hagege J, Peraldi MN, Rondeau E, Shieh YSC: See Gerber MA, Shieh YSC, Shim KS, Thung Adida C, Delarue F, Medcalf R, Schleuning WD, Sraer SN, Demetris AJ, Schwartz M, Akyol G, Dash S: 1271 JD, 117 Shimada K: See Murakami T, Yi S, Maeda S, Tashiro F, Schnitzer B: See Ross CW, Schlegelmilch JA, Grogan Yamamura KI, Takahashi K, Shimada K, Araki S, 451 TM, Weiss LM, Schnitzer B, Hanson CA, 457 Shim KS: See Gerber MA, Shieh YSC, Shim KS, Thung Schoen FJ: See Webb CL, Nguyen NM, Schoen FJ, SN, Demetris AJ, Schwartz M, Akyol G, Dash S: 1271 Levy RJ, 487 Shimokamam T: See Yamada T, Fan J, Shimokamam T, Schofield DE, Fletcher JA: Trisomy 12 in Pediatric Tokunaga 0, Watanabe T: 1435 Granulosa-Stromal Cell Tumors: Demonstration by a Shintaku IP: See Said JW, Barrera R, Shintaku IP, Naka- Modified Method of Fluorescence In-situ Hybridization mura H, Koeffler HP: 1343 on Paraffin-Embedded Material (December): 1265 Shiota M: See Aster JC, Kobayashi Y, Shiota M, Mori S, Schuurman HJ: See Parmentier HK, van Wichen DF, Sklar J, 291 Meyling FHJG, Gouldsmit J, Schuurman HJ: 1209 Simpson JF, Page DL: Altered Expression of a Struc- Schwan TG: See Czub S, Duray PH, Thomas RE, tural Protein (Fodrin) Within Epithelial Proliferative Dis- Schwan TG: 1173 ease of the Breast (August), 285 Schwartz M: See Gerber MA, Shieh YSC, Shim KS, Singer GG: See Jevnikar AM, Singer GG, Brennan DC, Thung SN, Demetris AJ, Schwartz M, Akyol G, Dash S: Xu HW, Kelley VR, 743 1271 Sisodia SS: See Price DL, Walker LC, Martin LJ, Sisodia Schwarz J: See Frizelle S, Schwarz J, Huber SA, Leslie SS, 767 K, 203 Sisto M: See Penneys NS, Bogaert M, Serfling U, Sisto Scott B: See Lo D, Quill H, Burkly L, Scott B, Palmiter RD, M, 139 Brinster RL: 1237 Sklar J: See Aster JC, Kobayashi Y, Shiota M, Mori S, Scott-Burden T: See Mackie EJ, Scott-Burden T, Hahn Sklar J, 291 AWA, Kern F, Bernhardt J, Regenass S, Weller A, Sletten K: See Johnson KH, Sletten K, Hayden DW, BOhler FR, 377 O'Brien TD, Roertgen KE, Westermark P: 1013 Seftel H: See Sugiyama N, Marcovina S, Gown AM, Sef- Sloan P: See Herrick SE, Sloan P, McGurk M, Freak L, tel H, Joffe B, Chait A, 99 McCollum CN, Ferguson MWJ: 1085 Segal GH, Wittwer CT, Fishleder AJ, Stoler MH, Smedts F, Ramaekers F, Troyanovsky S, Pruszc- Tubbs RR, Kjeldsberg CR: Identification of Monoclo- zynski M, Link M, Lane B, Leigh 1, Schijf C, Vooijs nal B-cell Populations by Rapid Cycle Polymerase P: Keratin Expression in Cervical Cancer (August), 497 Chain Reaction (December): 1291 Smith MO: See Sasseville VG, Newman WA, Lackner Seizinger BR: See Louis DN, von Deimling A, Seizinger AA, Smith MO, Lausen NCG, Beall D, Ringler D: 1021 BR, 777 Smolle J: See Dinges HP, Zatloukal K, Denk H, Smolle J, Selkoe DJ: See Yamaguchi H, Yamazaki T, Lemere CA, Mair S, 69 Frosch MP, Selkoe DJ, 249 Smoller BR: See Davis RE, Smoller BR, 691 Senoo A: See Takeuchi A, Yoshizawa N, Yamamoto M, Sobel ME: See Campo E, Monteagudo C, Castronovo V, Sawasaki Y, Oda T, Senoo A, Niwa H, Fuse Y, 107 Claysmith AP, Fernandez PL, Sobel ME: 1073 Serfling U: See Penneys NS, Bogaert M, Serfling U, Sisto Sol6 M: See Campistol JM, Sol6 M, Bombi JA, Rodriguez M, 139 R, Mirapeix E, Mufoz-Gomez J, Revert OW, 241 Shafritz DA: See Alpini G, Aragona E, Dabeva M, Salvi Sonbati H: See Ross JS, Bui HX, del Rosario A, Sonbati R, Shafritz DA, Tavoloni N, 623 H, George M, Lee CY, 721 Shainoff JR: See Valenzuela R, Shainoff JR, DiBello PM, Urbanic DA, Anderson JM, Matsueda GR, Kudryk BJ, Spratt RA: See de la Monte SM, Spratt RA, Chong J, 861 Ghanbari HA, Wands JR: 1459 Sharma S: See Tiitta 0, Wahlstrom T, Paavonen J, Lin- Spruck CH: See Shibata D, Hawes D, Li ZH, Hernandez nala A, Sharma S, Gould VE, Virtanen I, 907 AM, Spruck CH, Nichols PW, 539 Shea CR, McNutt NS, Volkenandt M, Lugo J, Sraer JD: See Hagege J, Peraldi MN, Rondeau E, Adida Prioleau PG, Albino AP: Overexpression of p53 Pro- C, Delarue F, Medcalf R, Schleuning WD, Sraer JD, 1 17 tein in Basal Cell Carcinomas of Human Skin (July), 25 Stachura 1: See Yang GCH, Nieto R, Stachura I, Gallo Shibata D, Hawes D, Li ZH, Hernandez AM, Spruck GR, 409 CH, Nichols PW: Specific Genetic Analysis of Micro- Stamp GWH: See Poulsom R, Pignatelli M, Stetler-Ste- scopic Tissue After Selective Ultraviolet Radiation Frac- venson WG, Liofta LA, Wright PA, Jeffery RE, Long- tionation and the Polymerase Chain Reaction (Sep- croft JM, Rogers L, Stamp GWH, 389 tember), 539 Standiford TJ: See Strieter RM, Kasahara K, Allen RM, Index of Authors 1545 AJP December 1992, Vol. 141, No. 6

Standiford TJ, Rolfe MW, Becker FS, Chensue SW, Takahashi K: See Naito M, Suzuki H, Mori T, Matsumoto Kunkel SL, 397 A, Kodama T, Takahashi K, 591 Steinberg H: See Peters DN, Steinberg H, Anderson WI, Takahashi K: See Sarker AB, Akagi T, Jeon HJ, Miyake Hornbuckle WE, Cote PJ, Gerin JL, Lewis RM, Tennant K, Murakami 1, Yoshino T, Takahashi K, Nose S, 19 BC, 143 Takeuchi A, Yoshizawa N, Yamamoto M, Sawasaki Steplewski Z: See Rakowicz-Szulczynska EM, Ste- Y, Oda T, Senoo A, Niwa H, Fuse Y: Basic Fibro- plewski Z, Koprowski H, 937 blast Growth Factor Promotes Proliferation of Rat Glo- Sterry W, Mielke V, Konter U, Kellner 1, Boehncke merular Visceral Epithelial Cells In Vitro (July), 107 WH: Role of 31 -Integrins in Epidermotropism of Malig- Talmage D: See Hillemanns P, Tannous-Khuri L, Koulos nant T Cells (October), 855 JP, Talmage D, Wright TC Jr, 973 Stetler-Stevenson WG: See Poulsom R, Pignatelli M, Tannous-Khuri L: See Hillemanns P, Tannous-Khuri L, Stetler-Stevenson WG, Liotta LA, Wright PA, Jeffery Koulos JP, Talmage D, Wright TC Jr, 973 RE, Longcroft JM, Rogers L, Stamp GWH, 389 Tarkkanen A: See Fuchs U, Kivela T, Summanen P, Im- Stevens JL: See Ward JM, Stevens JL, Konishi N, Kur- monen 1, Tarkkanen A, 169 ata Y, Uno H, Diwan BA, Ohmori T, 955 Tarr6s MC, Martinez SM, Montenegro S, Llorens A, Stoler MH: See Segal GH, Wittwer CT, Fishleder AJ, Picena JC, Naves A: The eSS Rat: A Model of Non-in- Stoler MH, Tubbs RR, Kjeldsberg CR: 1291 sulin-dependent Human Diabetes (September), 761 Stolk J: See Rudolphus A, Stolk J, van Twisk C, van Tashiro F: See Murakami T, Yi S, Maeda S, Tashiro F, Noorden CJF, Dijkman JH, Kramps JA, 153 Yamamura KI, Takahashi K, Shimada K, Araki S, 451 Strieter RM, Kasahara K, Allen RM, Standiford TJ, Tateishi J: See Kitamoto T, Doh-ura K, Muramoto T, Rolfe MW, Becker FS, Chensue SW, Kunkel SL: Miyazono M, Tateishi J, 271 Cytokine-induced Neutrophil-derived Interleukin-8 (Au- TSuber MG, Kennedy SL, Tureen JH, Lowenstein gust), 397 DH: Experimental Pneumococcal Meningitis Causes Strieter RM, Kunkel SL, Elner VM, Martonyi CL, Central Nervous System Pathology Without Inducing Koch AE, Polverini PJ, Elner SG: Interleukin-8 A the 72-kd Heat Shock Protein (July), 53 Corneal Factor that Induces Neovascularization (De- Tavoloni N: See Alpini G, Aragona E, Dabeva M, Salvi R, cember): 1279 Shafritz DA, Tavoloni N, 623 Striker G: See Domagala W, Striker G, Szadowska A, Taylor RG: See Hensler ME, Frojmovic M, Taylor RG, Dukowicz A, Weber K, Osborn M: 1003 Hantgan RR, Lewis JC, 707 Sueishi K: See Sakuda H, Nakashima Y, Kuriyama S, Tennant BC: See Peters DN, Steinberg H, Anderson WI, Sueishi K: 1507 Hornbuckle WE, Cote PJ, Gerin JL, Lewis RM, Tennant Sugama K: See Sasaguri Y, Komiya S, Sugama K, Su- BC, 143 zuki K, Inoue A, Morimatsu M, Nagase H, 611 Terzi F: See Dubrulle MP, Terzi F, Gubler MC, Kleink- Sugiyama N, Marcovina S, Gown AM, Seftel H, necht C, Schaeverbeke M: 1481 Joffe B, Chait A: Immunohistochemical Distribution of Thomas RE: See Czub S, Duray PH, Thomas RE, Lipoprotein Epitopes in Xanthomata from Patients with Schwan TG: 1173 Familial Hypercholesterolemia (July), 99 Thompson RC: See Ulich TR, Guo K, Yin S, del Castillo Sullivan TA: See Fuhr JE, Kattine AA, Sullivan TA, Nel- J, Yi ES, Thompson RC, Eisenberg SP, 61 son HS Jr, 211 Thung SN: See Gerber MA, Shieh YSC, Shim KS, Thung Summanen P: See Fuchs U, KivelS T, Summanen P, SN, Demetris AJ, Schwartz M, Akyol G, Dash S: 1271 Immonen 1, Tarkkanen A, 169 Tiberti G: See Olivetti G, Quaini F, Lagrasta C, Ricci R, Sutjipto S: See Miller CJ, Vogel P, Alexander NJ, Sutjipto Tiberti G, Capasso JM, Anversa P, 227 S, Hendrickx AG, Marx PA, 655 Tigges AJ: See van der Wal AC, Das PK, Tigges AJ, Suzuki H: See Naito M, Suzuki H, Mori T, Matsumoto A, Becker AE, 161 Kodama T, Takahashi K, 591 Tigges AJ: See van der Wal AC, Das PK, Tigges AJ, Suzuki K: See Sasaguri Y, Komiya S, Sugama K, Suzuki Becker AE: 1427 K, Inoue A, Morimatsu M, Nagase H, 611 Tiitta 0, Wahistrom T, Paavonen J, Linnala A, Szadowska A: See Domagala W, Striker G, Szadowska Sharma S, Gould VE, Virtanen 1: Enhanced Tena- A, Dukowicz A, Weber K, Osborn M: 1003 scin Expression in Cervical and Vulvar Koilocytotic Le- sions (October), 907 Taatjes DJ: See Holley JA, Janssen YMW, Mossman Timar J, Ladanyi A, Lapis K, Moczar M: Differential BT, Taatjes DJ, 475 Expression of Proteoglycans on the Surface of Human Takahashi K: See Murakami T, Yi S, Maeda S, Tashiro F, Melanoma Cells Characterized by Altered Experimen- Yamamura KI, Takahashi K, Shimada K, Araki S, 451 tal Metastatic Potential (August), 467 1546 Index of Authors AJP December 1992, Vol. 141, No. 6

Tinklenberg JR: See Murphy GM Jr, Greenberg BD, Meijer CJLM, Pinedo HM: Multidrug Resistance Ellis WG, Forno LS, Salamat SM, Gonzalez-DeWhitt Gene (P-Glycoprotein) Expression in the Human Fetus PA, Lowery DE, Tinklenberg JR, Eng LF, 357 (November): 1063 Tokunaga 0: See Yamada T, Fan J, Shimokamam T, van Noorden CJF: See Rudolphus A, Stolk J, van Twisk Tokunaga 0, Watanabe T: 1435 C, van Noorden CJF, Dijkman JH, Kramps JA, 153 Tonna-DeMasi M: See Wrzolek MA, Merz PA, Kascsak van Twisk C: See Rudolphus A, Stolk J, van Twisk C, R, Grundke-lqbal 1, Iqbal K, Rubenstein R, Tonna-De- van Noorden CJF, Dijkman JH, Kramps JA, 153 Masi M, Goller NL, Mehta P, Wisniewski HM, 343 van Wichen DF: See Parmentier HK, van Wichen DF, Troyanovsky S: See Smedts F, Ramaekers F, Troyan- Meyling FHJG, Gouldsmit J, Schuurman HJ: 1209 ovsky S, Pruszczynski M, Link M, Lane B, Leigh I, Schijf Vaquero J, Zurita M, Oya S, Arias A, Moreno M, Mo- C, Vooijs P, 497 rales C: Synaptophysin Expression in "Ependymal Tsao GJY: See Crabb ID, Hughes SS, Hicks DG, Puzas Tumors" Induced by Ethylnitosourea in Rats (No- JE, Tsao GJY, Rosier RN, 579 vember): 1037 Tubbs RR: See Segal GH, Wittwer CT, Fishleder AJ, Vignati S: See Fontanini G, Pingitore R, Bigini D, Vignati Stoler MH, Tubbs RR, Kjeldsberg CR: 1291 S, Pepe S, Ruggiero A, Macchiarini P: 1285 Tureen JH: See Tauber MG, Kennedy SL, Tureen JH, Virtanen 1: See Korhonen M, Laitinen L, Ylanne J, Kou- Lowenstein DH, 53 koulis GK, Quaranta V, Juusela H, Gould VE, Virtanen I: 1161 Ulich TR, Guo K, Yin S, del Castillo J, Yi ES, Thomp- Virtanen 1: See Tiitta 0, WahIstrOm T, Paavonen J, Lin- son RC, Eisenberg SP: Endotoxin-induced Cytokine nala A, Sharma S, Gould VE, Virtanen I, 907 Gene Expression In Vivo: IV. Expression of Interleukin- Vogel P: See Miller CJ, Vogel P, Alexander NJ, Sutjipto S, 1 a#/ and Interleukin-1 Receptor Antagonist mRNA Hendrickx AG, Marx PA, 655 During Endotoxemia and Endotoxin-initiated Local Vogelstein B: See Mulder JWR, Offerhaus GJA, de Acute Inflammation (July), 61 Feyter EP, Floyd JJ, Kern SE, Vogelstein B, Hamilton Uno H: See Ward JM, Stevens JL, Konishi N, Kurata Y, SR, 797 Uno H, Diwan BA, Ohmori T, 955 Volkenandt M: See Shea CR, McNutt NS, Volkenandt Urbanic DA: See Valenzuela R, Shainoff JR, DiBello PM, M, Lugo J, Prioleau PG, Albino AP, 25 Urbanic DA, Anderson JM, Matsueda GR, Kudryk BJ, von Deimling A: See Louis DN, von Deimling A, Sei- 861 zinger BR, 777 Vooijs P: See Smedts F, Ramaekers F, Troyanovsky S, Valenzuela R, Shainoff JR, DiBello PM, Urbanic DA, Pruszczynski M, Link M, Lane B, Leigh 1, Schijf C, Anderson JM, Matsueda GR, Kudryk BJ: Immun- Vooijs P, 497 oelectrophoretic and Immunohistochemical Character- izations of Fibrinogen Derivatives in Atherosclerotic Wahistrom T: See Tiitta 0, WahIstrOrm T, Paavonen J, Aortic Intimas and Vascular Prosthesis Pseudo-intimas Linnala A, Sharma S, Gould VE, Virtanen 1, 907 (October), 861 Waldron JA Jr: See Hsu SM, Xie SS, Hsu PL, Waldron VandenBerg SR: See Gonzalez-Fernandez F, Lopes JA Jr, 129 MBS, Garcia-Fernandez JM, Foster RG, De Grip WJ, Waldron JA Jr: See Hsu SM, Xie SS, Waldron JA Jr, 915 Rosemberg S, Newman SA, VandenBerg SR, 363 Waldron JA Jr: See Macon WR, VandenBerg SR: See Wolf BB, Lopes MBS, Vanden- Cousar JB, Waldron JA Berg SR, Gonias SL, 37 Jr, Hsu SM: 1031 van der Valk P: See van Kalken CK, Giaccone G, van Walker LC: See Price DL, Walker LC, Martin LJ, Sisodia der Valk P, Kuiper CM, Hadisaputro MMN, Bosma SS, 767 SAA, Scheper RJ, Meijer CJLM, Pinedo HM: 1063 Wands JR: See de la Monte SM, Spraft RA, Chong J, van der Wal AC, Das PK, Tigges AJ, Becker AE: Ghanbari HA, Wands JR: 1459 Adhesion Molecules on the Endothelium and Mononu- Wang CZ, Evans MJ, Cox RA, Burke AS, Zhu Q, clear Cells in Human Atherosclerotic Lesions (De- Herndon DN, Barrow RE: Morphologic Changes in cember): 1427 Basal Cells During Repair of Tracheal Epithelium (Sep- van der Wal AC, Das PK, Tigges AJ, Becker AE: tember), 753 Macrophage Differentiation in Atherosclerosis: An in Wang S: See Ladanyi M, Wang S, Niesvizky R, Feiner H, Situ Immunohistochemical Analysis in Humans (July), Michaeli J, 949 161 Ward JM, Stevens JL, Konishi N, Kurata Y, Uno H, van Kalken CK, Giaccone G, van der Valk P, Kuiper Diwan BA, Ohmori T: Vimentin Metaplasia in Renal CM, Hadisaputro MMN, Bosma SAA, Scheper RJ, Cortical Tubules of Preneoplastic, Neoplastic, Aging, Index of Authors 1547 AJP December 1992, Vol. 141, No. 6

and Regenerative Lesion of Rats and Humans (Oc- tion of a2-Macroglobulin Receptor (Low-density Lipo- tober), 955 protein Receptor-related Protein) in Human Brain (July), Warner JA: See Dvorak AM, Warner JA, Morgan E, Kis- 37 sell-Rainville S, Lichtenstein LM, MacGlashan DW Jr: Wolf ML: See Goldfarb AN, Wolf ML, Greenberg JM: 1309 1125 Warnke RA: See Gelb AB, Kamel OW, LeBrun DP, Wood GS, Freudenthal PS: CD5 Monoclonal Antibod- Warnke RA: 1453 ies React with Human Peripheral Blood Dendritic Cells Warren JS: Relationship Between Interleukin-1f3 and (October), 789 Platelet-activating Factor in the Pathogenesis of Acute Wright DH: See Isaacson PG, Androulakis-Papachristou Immune Complex Alveolitis in the Rat (September), A, Diss TC, Pan L, Wright DH, 43 551 Wright PA: See Poulsom R, Pignatelli M, Stetler-Steven- Watanabe T: See Yamada T, Fan J, Shimokamam T, son WG, Liotta LA, Wright PA, Jeffery RE, Longcroft Tokunaga 0, Watanabe T: 1435 JM, Rogers L, Stamp GWH, 389 Watkins SC: See Bogen SA, Baldwin HS, Watkins SC, Wright TC Jr: See Hillemanns P, Tannous-Khuri L, Kou- Albelda SM, Abbas AK, 843 los JP, Talmage D, Wright TC Jr, 973 Webb CL, Nguyen NM, Schoen FJ, Levy RJ: Calcifi- Wrzolek MA, Merz PA, Kascsak R, Grundke-lqbal 1, cation of Allograft Aortic Wall in a Rat Subdermal lqbal K, Rubenstein R, Tonna-DeMasi M, Goller Model: Pathophysiology and Inhibition by Al3+ and NL, Mehta P, Wisniewski HM: Immune Electron Mi- Aminodiphosphonate Preincubations (August), 487 croscopic Characterization of Monoclonal Antibodies Weber K: See Domagala W, Striker G, Szadowska A, to Alzheimer Neurofibrillary Tangles (August), 343 Dukowicz A, Weber K, Osborn M: 1003 Wu TC, Lee WA, Pizzorno MC, Au WC, Chan YJ, Weinberg DS: See Huettner PC, Weinberg DS, Lage JM, Hruban RH, Hutchins GM, Hayward GS: Localiza- 699 tion of the Human Cytomegalovirus 2.7-kb Major Early Weinberg DS: See Munro JM, Lo SK, Corless C, Robert- f-gene Transcripts by RNA In Situ Hybridization in Per- son MJ, Lee NC, Barnhill RL, Weinberg DS, Bevilacqua missive and Nonpermissive Infections (November): MP: 1397 1247 Weiss LM: See Ross CW, Schlegelmilch JA, Grogan TM, Weiss LM, Schnitzer B, Hanson CA, 457 Xie SS: See Collins CL, Ordonez NG, Schaefer R, Cook Weller A: See Mackie EJ, Scoft-Burden T, Hahn AWA, CD, Xie SS, Granger J, Hsu PL, Fink L, Hsu SM, 827 Kern F, Bernhardt J, Regenass S, Weller A, BOhler FR, Xie SS: See Hsu SM, Xie SS, Hsu PL, Waldron JA Jr, 129 377 Xie SS: See Hsu SM, Xie SS, Waldron JA Jr, 915 Westermark P: See Johnson KH, Sletten K, Hayden Xu HW: See Jevnikar AM, Singer GG, Brennan DC, Xu DW, O'Brien TD, Roertgen KE, Westermark P: 1013 HW, Kelley VR, 743 Wieczorek R: See Greco MA, Wieczorek R, Sachdev R, Kaplan C, Nuovo GJ, Demopoulos RI, 835 Yacoub M: See Page C, Rose M, Yacoub M, Pigott R, Wilkins RJ: See Gray ST, Wilkins RJ, Yun K, 301 673 Williams D: See Williams ED, Lowes AP, Williams D, Wil- Yamada T, Fan J, Shimokamam T, Tokunaga 0, liams GT, 773 Watanabe T: Induction of Fatty Streaklike Lesions In Williams ED, Lowes AP, Williams D, Williams GT: A Vitro Using a Culture Model System Simulating Arterial Stem Cell Niche Theory of Intestinal Crypt Maintenance Intima (December): 1435 Based on a Study of Somatic Mutation in Colonic Mu- Yamaguchi H, Yamazaki T, Lemere CA, Frosch MP, cosa (October), 773 Selkoe DJ: Beta Amyloid is Focally Deposited Within Williams GT: See Williams ED, Lowes AP, Williams D, the Outer Basement Membrane in the Amyloid Angio- Williams GT, 773 pathy of Alzheimer's Disease: An Immunoelectron Mi- Wirtz HC: See Offner FA, Wirtz HC, Schiefer J, Bigalke 1, croscopic Study (July), 249 Klosterhalfen B, Bittinger F, Mittermayer C, Kirkpatrick Yamamoto M: See Takeuchi A, Yoshizawa N, Yama- CJ, 601 moto M, Sawasaki Y, Oda T, Senoo A, Niwa H, Fuse Y, Wisniewski HM: See Wrzolek MA, Merz PA, Kascsak R, 107 Grundke-lqbal I, lqbal K, Rubenstein R, Tonna-DeMasi Yamamura KI: See Murakami T, Yi S, Maeda S, Tashiro M, Goller NL, Mehta P, Wisniewski HM, 343 F, Yamamura KI, Takahashi K, Shimada K, Araki S, 451 Wittwer CT: See Segal GH, Wittwer CT, Fishleder AJ, Yamanaka E: See Isik FF, McDonald TO, Ferguson M, Stoler MH, Tubbs RR, Kjeldsberg CR: 1291 Yamanaka E, Gordon D: 1 139 Wolf BB, Lopes MBS, VandenBerg SR, Gonias SL: Yamazaki T: See Yamaguchi H, Yamazaki T, Lemere Characterization and Immunohistochemical Localiza- CA, Frosch MP, Selkoe DJ, 249 1548 Index of Authors AJP December 1992, Vol. 141, No. 6

Yang GCH, Nieto R, Stachura 1, Gallo GR: Ultrastruc- Yun K: See Gray ST, Wilkins RJ, Yun K, 301 tural Immunohistochemical Localization of Polyclonal Yu QC, McNeil PL: Transient Disruptions of Aortic Endo- IgG, C3, and Amyloid P Component on the Congo thelial Cell Plasma Membranes (December): 1349 Red-negative Amyloid-like Fibrils of Fibrillary Glomeru- lopathy (August), 409 Zarbo RJ: See Coltrera MD, Zarbo RJ, Sakr WA, Gown Yi ES: See Ulich TR, Guo K, Yin S, del Castillo J, Yi ES, AM, 817 Thompson RC, Eisenberg SP, 61 Zatloukal K: See Dinges HP, Zatloukal K, Denk H, Yin S: See Ulich TR, Guo K, Yin S, del Castillo J, Yi ES, Smolle J, Mair S, 69 Thompson RC, Eisenberg SP, 61 Zeymer U, Fishbein MC, Forrester JS, Cercek B: Yi S: See Murakami T, Yi S, Maeda S, Tashiro F, Yama- Proliferating Cell Nuclear Antigen Immunohistoche- mura KI, Takahashi K, Shimada K, Araki S, 451 mistry in Rat Aorta After Balloon Denudation: Compari- Ylanne J: See Korhonen M, Laitinen L, Ylanne J, Kou- son with Thymidine and Bromodeoxyuridine Labeling koulis GK, Quaranta V, Juusela H, Gould VE, Virtanen I: (September), 685 1161 Zhang RD, Price JE, Fujimaki T, Bucana CD, Fidler Yoshida Y, Dereski MO, Garcia JH, Hetzel FW, IJ: Differential Permeability of the Blood-Brain Barrier Chopp M: Neuronal Injury After Photoactivation of in Experimental Brain Metastases Produced by Human Photofrin II (October), 989 Neoplasms Implanted into Nude Mice (November): Yoshino T: See Sarker AB, Akagi T, Jeon HJ, Miyake K, 1115 Murakami I, Yoshino T, Takahashi K, Nose S, 19 Zhu 0: See Wang CZ, Evans MJ, Cox RA, Burke AS, Zhu Yoshizawa N: See Takeuchi A, Yoshizawa N, Yama- Q, Herndon DN, Barrow RE, 753 moto M, Sawasaki Y, Oda T, Senoo A, Niwa H, Fuse Y, Zink MC: See Sack GH Jr, Zink MC, 525 107 Zurita M: See Vaquero J, Zurita M, Oya S, Arias A, Mor- Youle RJ: See Dipasquale B, Youle RJ: 1471 eno M, Morales C: 1037 The American Journal of PATHOLOGY Official Publication ofthe American Association ofPathologists VOLUME 141, 1992 (July through December)

Editor-in-Chief Editorial Board Nelson Fausto Abul K. Abbas Ricardo V. Lloyd Brown University H. Clarke Anderson James L. Madara Dorothy F. Bainton Glenn Merlino Associate Editors Hector Battifora Alfred F. Michael H. Jeffrey Cossman Frederick Miller Sandra Bigner Riccardo Dalla-Favera George F. Murphy Duke University Dennis W. Dickson Brian J. Nickoloff Francis V. Chisari Robert E. Fechner Paul K. Pattengale Scripps Research Institute Victor J. Ferrans George Perry Isaiah J. Fidler R. Neal Pinckard Stanley R. Hamilton Michael A. Gimbrone, Jr. Jordan S. Pober Johns Hopkins University James E. Goldman Juan Rosai Nicholas K. Gonatas Russell Ross Agnes B. Kane Nancy L. Harris Eric P. Sandgren Brown University Aubrey J. Hough, Jr. Gary E. Striker Steven L. Kunkel Peter M. Howley Thomas W. Tillack University of Michigan Philip M. lannaccone Manjeri A. Venkatachalam Harriet Isom Peter A. Ward Joseph A. Madri Elaine S. Jaffe Roger A. Warnke Yale University Yashpal S. Kanwar Lawrence M. Weiss Daniel M. Knowles James G. White George M. Martin Charles Kuhn Mark R. Wick University of Washington Paul E. Lacy Peter D. Yurchenco Jeffrey L. Sklar Lance A. Liotta Dorothea Zucker-Franklin Harvard University Managing Editor Marcia M. Robinson

Copyright C) 1992 By The American Association of Pathologists The American Journal of PATHOLOGY CONTENTS FOR VOLUME 141 July 1992

Editorial 1 A New Phase for The AJP Nelson Fausto, Editor-in-Chief Short Communications 3 The NIH-3 Immunodeficient Mouse Is a Model for Lyme Borreliosis Myositis and Carditis Dana L. Defosse, Paul H. Duray, and Russell C Johnson 11 Inconsistency of the Immunophenotype of Reed-Sternberg Cells in Simultaneous and Consecutive Specimens from the Same Patients: A Paraffin Section Evaluation in 56 Patients Wei-Sing Chu, Susan L. Abbondanzo, and Glauco Frizzera 19 Bauhinia Purpurea-A New Paraffin Section Marker for Reed-Sternberg Cells of Hodgkin's Disease: A Comparison with Leu-M1 (CD15), LN2 (CD74), Peanut Agglutinin, and Ber-H2 (CD30) Ashit Baran Sarker, Tadaatsu Akagi, Ho JongJeon, Kenji Miyake, Ichiro Murakami, Tadashi Yoshino, Kiyoshi Takahashi, and Soichiro Nose 25 Overexpression of p53 Protein in Basal Cell Carcinomas of Human Skin Christopher R. Shea, N Scott McNutt, Matthias Volkenandt, Jorge Lugo, Philip G. Prioleau, and Anthony P. Albino 31 Light and Electron Microscopic Localization of 0-amyloid Protein in Muscle Biopsies of Patients with Inclusion-body Myositis Valerie Askanas, W King Engel, and Renate B. Alvarez 37 Characterization and Immunohistochemical Localization of a2-Macroglobulin Receptor (Low-density Lipoprotein Receptor-related Protein) in Human Brain Beni B. Wolf; M. Beatriz S. Lopes, Scott R. VandenBerg, and Steven L. Gonias Regular Articles 43 Follicular Colonization in Thyroid Lymphoma Peter G. Isaacson, Athina Androulak*-Papachristou, Tim C Diss, Langxing Pan, and Dennis H. Wright 53 Experimental Pneumococcal Meningitis Causes Central Nervous System Pathology Without Inducing the 72-kd Heat Shock Protein Martin G. Tauber, Stephen L. Kennedy, Jay H. Tureen, and Daniel H. Lowenstein 61 Endotoxin-induced Cytokine Gene Expression In Vivo: IV. Expression of Interleukin-l,/B and Interleukin-1 Receptor Antagonist mRNA During Endotoxemia and Endotoxin-inititated Local Acute Inflammation ThomasR. Ulich, Kaizhi Guo, Songmei Yin, Juan del Castillo, EunheeS Yi, Robert C Thompson, and Stephen P. Eisenberg 69 Alcoholic Liver Disease: Parenchyma to Stroma Relationship in Fibrosis and Cirrhosis as Revealed by Three-dimensional Reconstruction and Immunohistochemistry Hans PeterDinges, Kurt Zatloukal, HelmutDenk, JosefSmolle, and SabineMair 85 Structural Characterization of the Mesangial Cell Type IV Collagenase and Enhanced Expression in a Model of Immune Complex-mediated Glomerulonephritis DavidH. Lovett, Richard.Johnson, Hans-PeterMarti, John Martin, Malcolm Davies, and William G. Couser 99 Immunohistochemical Distribution of Lipoprotein Epitopes in Xanthomata from Patients with Familial Hypercholesterolemia NobutoshiSug:yama, SanticaMarcovina, Allen M. Gown, Harry Seftel, BarryJoffe, and Alan Chait 107 Basic Fibroblast Growth Factor Promotes Proliferation of Rat Glomerular Visceral Epithelial Cells In Vitro Akihiko Takeuchi, Nobuyuki Yoshizawa, Mikio Yamamoto, Yoshio Sawasaki, Takashi Oda, Akira Senoo, HirobumiNiwa, and Yusuke Fuse 117 Plasminogen Activator Inhibitor-1 Deposition in the Extracellular Matrix of Cultured Human Mesangial Cells J. Hagege, M N Peraldi, E. Rondeau, C. Adida, F Delarue, R. Medcalf W D. Scbleuning, andJ. D. Sraer 129 Interleukin-6, But Not Interleukin-4, Is Expressed by Reed-Sternberg Cells in Hodgkin's Disease with or without Histologic Features of Castleman's Disease Su-MingHsu, Su-SuXie, Pei-LingHsu, andJamesA. Waldron,Jr. 139 PCNA Expression in Cutaneous Keratinous Neoplasms and Verruca Vulgaris Neal S. Penneys, Maria Bogaert, Ulrike Serfling, and Manuel Sisto 143 Immunopathology of Glomerulonephritis Associated with Chronic Woodchuck Hepatitis Virus Infection in Woodchucks (Marmota monax) DavidN. Peters, HowardSteinberg, Wayne I. Anderson, William E. Hornbuckle, Paulj Cote, Jobn L. Gern, RobertM Lewis, and Bud C. Tennant 153 Detection of Extracellular Neutrophil Elastase in Hamster Lungs After Intratracheal Instillation of E. Coli Lipopolysaccharide Using a Fluorogenic, Elastase-specific, Synthetic Substrate A. Rudolphus, J. Stolk, C van Twisk, C.. F. van Noorden, J. H. Dykman, and J A. Kramps 161 Macrophage Differentiation in Atherosclerosis: An in Situ Immunohistochemical Analysis in Humans Allard C van der Wal, Pranab K Das, AlbertJ Tigges, and Anton E. Becker 169 An Immunohistochemical and Prognostic Analysis of Cytokeratin Expression in Malignant Uveal Melanoma Utrich Fuchs, Tero Kivela, Paula Summanen, Ilkka Immonen, and Ahti Tarkkanen 183 Chronic Hemodynamic Unloading Regulates the Morphologic Development of Newborn Mouse Hearts Transplanted into the Ear of Isogenic Adult Mice MarcosA. Rossi 193 The bcl-2 Gene Translocation Is Undetectable in Hodgkin's Disease by Southern Blot Hybridization and Polymerase Chain Reaction EleniAthan, Amy Chadburn, and DanielM. Knowles 203 Evaluation of the Effects of Low Molecular Weight Heparin on Inflammation and Collagen Deposition in Chronic Coxsackievirus B3-induced Myocarditis in A/J Mice S. Frizelle, J. Scbwarz, S. A. Huber, and K Leslie 211 Flow Cytometric Analysis of Pulmonary Fluids and Cells for the Detection of Malignancies Joseph E. Fuhr, Antbony A. Kattine, ThomasA. Sullivan, and H. Sperry Nelson,Jr. 217 Immunohistochemical Characterization of Amyloid Proteins in Sural Nerves and Clinical Associations in Amyloid Neuropathy Kunio Ii, RobertA. Kyle, and PeterJames Dyck 227 Myocyte Cellular Hypertrophy and Hyperplasia Contribute to Ventricular Wall Remodeling in Anemia-induced Cardiac Hypertrophy in Rats Giorgio Olivetti, Fedenco Quaini, Costanza Lagrasta, Roberto Ricci, Gianluca Tiberti, Joseph M Capassso, and Piero Anversa 241 In Vitro Spontaneous Synthesis of P2-microglobulin Amyloid Fibrils in Peripheral Blood Mononuclear Cell Culture j M. Campistol, M. Sole, J. A. Bombi, R. Rodriguez, E. Mirapeix, J Munioz-Gomez, and 0. W Revert 249 Beta Amyloid Is Focally Deposited Within the Outer Basement Membrane in the Amyloid Angiopathy of Alzheimer's Disease: An Immunoelectron Microscopic Study H. Yamaguchi, T. Yamazaki, C. A. Lemere, M. P. Frosch, and D. j Selkoe

August 1992

Short Communications 271 The Primary Structure of the Prion Protein Influences the Distribution of Abnormal Prion Protein in the Central Nervous System Tetsuyuki Kitamoto, Katsumi Dob-ura, TamakiMuramoto, MasayukiMiyazono, andJun Tateishi 279 Glomerular Epithelial Cells Synthesize Endothelin Peptides B. S. Kasinath, T A. Fried, S. Davalath, and P. A. Marsden 285 Altered Expression of a Structural Protein (Fodrin) Within Epithelial Proliferative Disease of the Breast Jean F. Simpson and David L. Page 291 Detection of the t(14;1 8) at Similar Frequencies in Hyperplastic Lymphoid Tissues from American and Japanese Patients Jon C Aster, Yukio Kobavashi, MamiShiota, Shigeo Mori, andJeffrey Sklar 301 Interstitial Collagenase Gene Expression in Oral Squamous Cell Carcinoma S. T Gray, R. J. Wilkins, and K Yun

Regular Articles 307 In Vivo Effects of Endotoxin on Intraepithelial Mucosubstances in Rat Pulmonary Airways: Quantitative Histochemistry JackR. Harkema andJon A. Hotchkiss 319 Instillation of Chemotactic Factor to Silica-injected Lungs Lowers Interstitial Particle Content and Reduces Pulmonary Fibrosis I. Y R. Adamson, H. Prieditis, and D. H. Bouden 327 Recombinant Interleukin-6 Inhibits the Growth of Rat Mesangial Cells in Culture Michiyo Ikeda, Uichi Ikeda, Tomoko Ohara, Eii Kusano, and Shogo Kano 335 Autoantibodies Developing to Myloperoxidase and Proteinase 3 in Systemic Vasculitis Stimulate Neutrophil Cytotoxicity Toward Cultured Endothelial Cells Caroline 0. S. Savage, Bruce E. Pottinger, Gillian Gaskin, CharlesD. Pusey), andJeremy D. Pearson 343 Immune Electron Microscopic Characterization of Monoclonal Antibodies to Alzheimer Neurofibrillary Tangles MonikaA. Wrzolek, Patricia A. Merz, Richard Kascsak, Inge Grundke-Iqbal, Khalid Iqbal, RichardRubenstein, Maria Tonna-DeMasi, NancV L. Goller, PankajMehta, and Henryk M. Wisniewski 357 Alzheimer's Disease: P-amyloid Precursor Protein Expression in the Nucleus Basalis of Meynert GreerM Murphy,Jr., BarryD. Greenberg, William G. Ellis, Lysia S. Forno, ShabriarM. Salamat, Patricia A. Gonzalez-DeWhitt, DavidE. Lowery, Jared R. Tinklenberg, and Lawrence F. Eng 363 Expression of Developmentally Defined Retinal Phenotypes in the Histogenesis of Retinoblastoma Federico Gonzalez-Fernandez, M. Beatriz S. Lopes, Jose M. Garcia-Fernandez, Russell G. Foster, WillemJ. De Grip, Sergio Rosemberg, Steven A. Newman, and Scott R. VandenBerg 377 Expression of Tenascin by Vascular Smooth Muscle Cells: Alterations in Hypertensive Rats and Stimulation by Angiotensin 11 EleanorJ Mackie, Timothy Scott-Burden, Alfred WA.Hahn, Frances Kern, JensBernhardt, Stephan Regenass, Andreas Weller, and Fritz R. Bahler 389 Stromal Expression of 72 kda Type IV Collagenase (MMP-2) and TIMP-2 mRNAs in Colorectal Neoplasia RichardPoulsom, Massimo Pignatelli, William G. Stetler-Stevenson, LanceA. Liotta, Patricia A. Wright, Rosemary E.Jeffery, JanetM. Longcroft, Len Rogers, and Gordon W H. Stamp 397 Cytokine-induced Neutrophil-derived Interleukin-8 RobertM Strieter, Keita Kasahara, RonaldM Allen, Theodoref Standiford, Mark W Rolfe, Frank S. Becker, Stephen W Chensue, and Steven L. Kunkel 409 Ultrastructural Immunohistochemical Localization of Polyclonal IgG, C3, and Amyloid P Component on the Congo Red-negative Amyloid-like Fibrils of Fibrillary Glomerulopathy Grace C H. Yang, RaulNieto, Irene Stachura, and Gloria R. Gallo 421 Brain Microvascular Smooth Muscle and Endothelial Cells Produce Granulocyte Macrophage Colony-stimulating Factor and Support Colony Formation of Granulocyte-Macrophage-like Cells MichaelN. Hart, Zsuzsanna Fabry, Laurie Love-Homan, Judy Keiner, Kathryn L. Sadewasser, and Steven A. Moore 429 Mesangial Cell-matrix Interactions: Effects on Mesangial Cell Growth and Cytokine Secretion Christian Ruef; Michael Kashgarian, and DavidL. Coleman 441 Epstein-Barr and Human Immunodeficiency Viruses in Acquired Immunodeficiency Syndrome-related Primary Central Nervous System Lymphoma Susan Morgello 451 Effect of Serum Amyloid P Component Level on Transthyretin-derived Amyloid Deposition in a Transgenic Mouse Model of Familial Amyloidotic Polyneuropathy TatsufumiMurakami, Shigehiro Yi, Shuichiro Maeda, Fumi Tashiro, Ken-ichi Yamamura, Kiyoshi Takabashi, KazunoriShimada, and Shukuro Araki 457 Detection of Epstein-Barr Virus Genome in Ki-1 (CD30)-positive, Large-cell Anaplastic Lymphomas Using the Polymerase Chain Reaction Charles W Ross, June A. Schlegelmilch, Thomas M. Grogan, Lawrence M. Weiss, Bertram Schnitzer, and Curtis A. Hanson 467 Differential Expression of Proteoglycans on the Surface of Human Melanoma Cells Characterized by Altered Experimental Metastatic Potential Jozsef 7imar, Andrea Ladani, Karoly Lapis, and Magdalene4Moczar 475 Increased Manganese Superoxide Dismutase Protein in Type II Epithelial Cells of Rat Lungs after Inhalation of Crocidolite Asbestos or Cristobalite Silica John A. Holle, Yvonne M. W janssen, Brooke 7 Mossman, and Douglasj Taat]es 487 Calcification of Allograft Aortic Wall in a Rat Subdermal Model: Pathophysiology and Inhibition by Al3+ and Aminodiphosphonate Preincubations Catherine L. Webb, Nguyet,l4. Nguy,en, Frederickj Schoen, and Roberti. Let y 497 Keratin Expression in Cervical Cancer Frank Smedts, Frans Ramaekers, Sergei Troyanovsky, M4aciejPruszcznski, Monique Link, Birgitte Lane, Irene Leigh, Charles Schiff and Peter Voois September 1992 Commentary 519 Expression of Multi-cytokine Resistance and Multi-growth Factor Independence in Advanced Stage Metastatic Cancer: Malignant Melanoma as a Paradigm R. S. Kerbel Short Communications 525 Serum Amyloid A Gene Transcription in Synovial Cells During Retroviral Arthritis George H. Sack, Jr. and M. Christine Zink 531 Detection of Bone Marrow Metastases in Small Cell Lung Cancer Patients: Comparison of Immunologic and Morphologic Methods K Beiske, A. T Myklebust, S. Aamdal, R. Langholm, E. Jakobsen, and 0. Fodstad 539 Specific Genetic Analysis of Microscopic Tissue After Selective Ultraviolet Radiation Fractionation and the Polymerase Chain Reaction Darryl Shibata, Debra Hawes, Zhi-Hua Li, Antonio M. Hernandez, Charles H. Spruck, and Peter W Nichols 545 In Situ Hybridization and Immunohistochemistry of p53 Tumor Suppressor Gene in Human Esophageal Carcinoma Hironobu Sasano, Yuji Goukon, Tetsuro Nishihira, and Hiroshi Nagura Regular Articles 551 Relationship Between Interleukin-1 I and Platelet-activating Factor in the Pathogenesis of Acute Immune Complex Alveolitis in the Rat Jeff3rey S. Warren 561 Influence of Genetics on the Nephritogenic Potential of Proteoglycans Brigitte Lelongt, Naoki Kashihara, Hirofumi Makino, Yashpal S. Kanwar 571 Characterization of Glomerular Epithelial Cell Matrix Receptors Stephen Adler 579 Nonradioactive In Situ Hybridization Using Digoxigenin-labeled Oligonucleotides: Applications to Musculoskeletal Tissues Ian D. Crabb, Steven S. Hughes, David G. Hicks, J Edward Puzas, GraceJ. Y Tsao, and Randy N Rosier 591 Coexpression of Type and Type 11 Human Macrophage Scavenger Receptors in Macrophages of Various Organs and Foam Cells in Atherosclerotic Lesions Makoto Naito, Hiroshi Suzuki, Takashi Mori, Akiyo Matsumoto, Tatsubiko Kodama, and Kiyoshi Takahashi 601 Interaction of Human Malignant Melanoma (ST-ML-1 2) Tumor Spheroids with Endothelial Cell Monolayers: Damage to Endothelium by Oxygen-derived Free Radicals Felix Albert Offner, Hans Christian Wirtz, Johannes Schiefer, Iris Bigalke, Bernd Klosterhalfen, Fernando Bittinger, Christian Mittermayer, and CharlesJames Kirkpatrick 611 Production of Matrix Metalloproteinases 2 and 3 (Stromelysin) by Stromal Cells of Giant Cell Tumor of Bone Yasuyuki Sasaguri, Setsuro Komiya, Kazushige Sugama, Ko Suzuki, Akio Inoue, Minoru Morimatsu, and Hideaki Nagase 623 Distribution of Albumin and Alpha-fetoprotein mRNAs in Normal, Hyperplastic, and Preneoplastic Rat Liver Gianfranco Alpini, Emma Aragona, Mariana Dabeva, Roberto Salvi, David A. Shafritz, and Nicola Tavoloni 633 Transforming Growth Factor-1 and Transforming Growth Factor ,-receptor Expression in Human Meningioma Cells Mahlon D. Johnson, Charles F. Federspiel, Leslie I. Gold, and Harold L. Moses 643 Localization of Transforming Growth Factor-a in Human Appendageal Tumors Eric Finzi Tony Ho, Grant Anhalt, Wendy Hawkins, Richard Harkins, and Thomas Horn 655 Localization of SIV in the Genital Tract of Chronically Infected Female Rhesus Macaques ChristopherJ Miller, Peter Vogel, NancyJ Alexander, Suganto Sutjipto, Andrew G. Hendrickx, and Preston A. Marx 661 Basic Fibroblast Growth Factor in Dupuytren's Contracture Ana-Maria Gonzalez, Marino Buscaglia, Robert Fox, Antonella Isacchi, Paolo Sarmientos, James Farris, Michael Ong, Darlene Martineau, Douglas A Lappi, and Andrew Baird 673 Antigenic Heterogeneity of Vascular Endothelium Christopher Page, Marlene Rose, Magdi Yacoub, and Rod Pigott 685 Proliferating Cell Nuclear Antigen Immunohistochemistry in Rat Aorta After Balloon Denudation: Comparison with Thymidine and Bromodeoxyuridine Labeling Uwe Zeymer, Michael C. Fishbein, James S. Forrester, and Bojan Cercek 691 T Lymphocytes Expressing HECA-452 Epitope Are Present in Cutaneous Acute Graft-versus-Host Disease and Erythema Multiforme, But Not in Acute Graft-versus-Host Disease in Gut Organs R. Eric Davis and Bruce R. Smoller 699 Assessment of Proliferative Activity in Ovarian Neoplasms by Flow and Static Cytometry: Correlation with Prognostic Features Phyllis C. Huettner, David S. Weinberg, andJanice M. Lage 707 Platelet Morphologic Changes and Fibrinogen Receptor Localization: Initial Responses in ADP-activated Human Platelets Mary E. Hensler, Mony Fro]movic, Richard G. Taylor, Roy R. Hantgan, andJon C Lewis 721 Helicobacter pylori: Its Role in the Pathogenesis of Peptic Ulcer Disease in a New Animal Model Jeffrey S. Ross, Hai X Bui, Arthur del Rosario, Hani Sonbati, Mary George, and C. Y Lee 729 Adhesion Receptor Profile of Thymic B-cell Lymphoma Anette Eichelmann, Karin Koretz, Gunhild Mechtersheimer, and Peter Moller 743 Dexamethasone Prevents Autoimmune Nephritis and Reduces Renal Expression of la But Not Costimulatory Signals Anthony M. Jenikar, Gary G. Singer, Daniel C. Brennan, Hong-wu Xu, and Vicki Rubin Kelley 753 Morphologic Changes in Basal Cells During Repair of Tracheal Epithelium Cheng-Z. Wang, MichaelJ. Evans, Robert A Cox, Ann S Burke, Qingyan Zhu, David N Hendon, and Robert E. Barrow Animal Model 761 The eSS Rat: A Model of Non-insulin-dependent Human Diabetes Maria Cristina Tarres, Stella Maris Martinez, Silvana Montenegro, Antonio Llorens, Juan Carlos Picena, and Ariel Naves October 1992 Commentary 767 Amyloidosis in Aging and Alzheimer's Disease Donald L. Price, Lary C Walker, LeeJ. Martin, and Sangram S. Sisodia Short Communications 773 A Stem Cell Niche Theory of Intestinal Crypt Maintenance Based on a Study of Somatic Mutation in Colonic Mucosa E. D. Williams, Alison P. Lowes, D. Williams, and G. T Williams 777 A (CA)n Dinucleotide Repeat Assay for Evaluating Loss of Allelic Heterozygosity in Small and Archival Human Brain Tumor Specimens David N. louis, Andreas von Deimling, and Bernd R. Seizinger 783 Immunohistochemical Identification of Thrombospondin in Normal Human Brain and in Alzheimer's Disease Luc Buee, Patrick R. Hof, David D. Roberts, Andre Delacourte, John H. Morrison, and Howard M Fillit 789 CD5 Monoclonal Antibodies React with Human Peripheral Blood Dendritic Cells Gary S. Wood and Peter S. Freudenthal Regular Articles 797 The Relationship of Quantitative Nuclear Morphology to Molecular Genetic Alterations in the Adenoma-Carcinoma Sequence of the Large Bowel Jan-Willem R. Mulder, G. Joban A Offerhaus, Eimert P. de Feyter, JeffreyJ Floyd, Scott E. Kern, Bert Vogelstein, and Stanley R. Hamilton 805 The Altered Glomerular Filtration Slits Seen in Puromycin Aminonucleoside Nephrosis and Protamine Sulfate-treated Rats Contain the Tight Junction Protein ZO-1 Hidetake Kurihara, James Melvin Anderson, Dontscho Ker]aschki, and Mailyn Gist Farquhar 817 Markers for Dysplasia of the Upper Aerodigestive Tract: Suprabasal Expression of PCNA, p53, and CK1 9 in Alcohol-fixed, Embedded Tissue Marc D. Coltrera, RichardJ. Zarbo, Wael A. Sakr, and Allen M Gown 827 Thrombomodulin Expression in Malignant Pleural Mesothelioma and Pulmonary Adenocarcinoma Curtis L. Collins, Nelson G. Ordonez, Robert Schaefer, Christine D. Cook, Su-Su Xie, John Granger, Pei-Ling Hsu, Louis Fink, and Su-Ming Hsu 835 Phenotype of Villous Stromal Cells in Placentas with Cytomegalovirus, Syphilis, and Nonspecific Villitis M Alba Greco, Rosemary Wieczorek, Ranjit Sacbdev, Cyntbia Kaplan, GerardJ. Nuovo, and Rita I. Demopoulos 843 Association of Murine CD31 with Transmigrating Lymphocytes Following Antigenic Stimulation Steven A. Bogen, H. Scott Baldwin, Simon C Watkins, Steven M. Albelda, and Abul K Abbas 855 Role of pi -Integrins in Epidermotropism of Malignant T Cells Wolfram Sterry, Volker Mielke, Ulrich Konter, Imke Kellner, and Wolf-Henning Boebncke 861 Immunoelectrophoretic and Immunohistochemical Characterizations of Fibrinogen Derivatives in Atherosclerotic Aortic Intimas and Vascular Prosthesis Pseudo-intimas Rafael Valenzuela, John R. Shainoff; Patricia M. DiBello, David A. Urbanic, James M. Anderson, Gary R. Matsueda, and Bohdan J. Kudryk 881 The Expression of the Hu (Paraneoplastic Encephalomyelitis/Sensory Neuronopathy) Antigen in Human Normal and Tumor Tissues Josep Dalmau, Henry M Furneaux, Carlos Cordon-Cardo, andJerome B. Posner 887 Glomerular Macrophages and the Mesangial Proliferative Response in the Experimental Nephrotic Syndrome Jonathan R. Diamond, Guobua Ding, Jeffery Frye, and Ivona-Pesek Diamond 895 Morphologic Effects of hGRH Gene Expression on the Pituitary, Liver, and Pancreas of MT-hGRH Transgenic Mice: An In Situ Hybridization Analysis Ricardo V Lloyd, LongJin, Annie Chang, Elzbieta Kulig, Sally A. Camper, Brian D. Ross, Thomas R. Downs, and Lawrence A Frobman 907 Enhanced Tenascin Expression in Cervical and Vulvar Koilocytotic Lesions Outi Tiitta, Torsten Wahlstrom, Jorma Paavonen, AuUi Linnala, Shoba Sharma, Victor E. Gould, and Ismo Virtanen 915 Functional Heterogeneity and Pathogenic Significance of Interleukin-6 in B-cell Lymphomas Su-Ming Hsu, Su-Su Xie, andJames A. Waldron, Jr. 925 Early Extracellular and Cellular Lipid Deposits in Aorta of Cholesterol-fed Rabbits John R. Guyton and Keith F. Klemp 937 Nuclear Translocation of Monoclonal Antibody Directed Against Cell-surface Carbohydrate Y Determinant Ewa M. Rakowicz-Szulczynska, Zenon Steplewski, and Hilary Koprowski 949 Proto-oncogene Analysis in Multiple Myeloma Marc Ladanyi, Su Wang, Ruben Niesvizky, Helen Feiner, andJoseph Michaeli 955 Vimentin Metaplasia in Renal Cortical Tubules of Preneoplastic, Neoplastic, Aging, and Regenerative Lesions of Rats and Humans Jerrold M Ward, James L. Stevens, Noboru Konishi, Yasushi Kurata, Hiroshi Uno, Bhalchandra A. Diwan, and Takaaki Obmori 965 Continuous Secretion of Monocyte Chemotactic Factors and Fibroblast Growth Factors by Alveolar Macrophages Following a Single Exposure to Bleomycin In Vitro Elizabeth M. Denholm 973 Localization of Cellular Retinoid-binding Proteins in Human Cervical Intraepithelial Neoplasia and Invasive Carcinoma Peter Hillemanns, Lamya Tannous-Khuri, John P. Koulos, David Talmage, and Thomas C Wright, Jr. 981 Expression of Macrophage Inflammatory Protein-2 and KC mRNA in Pulmonary Inflammation Songlih Huang, Joseph D. Paulauskis, John J. Godleski, and Lester Kobzik 989 Neuronal Injury After Photoactivation of Photofrin 11 Yasuji Yoshida, Mary 0. Dereski, Julio H. Garcia, Frederic W Hetzel, and Michael Chopp

November 1992

Short Communications 1003 Cathepsin D in Invasive Ductal NOS Breast Carcinoma as Defined by Immunohistochemistry: No Correlation with Survival at 5 Years Wenancjusz Domagala, George Striker, Anna Szadowska, Andrzej Dukowicz, Klaus Weber, and Mary Osborn 1013 Pulmonary Vascular Amyloidosis in Aged Dogs: A New Form of Spontaneously Occurring Amyloidosis Derived from Apolipoprotein Al K H. Johnson, K Sletten, D. W Hayden, T D. O'Brien, K E. Roertgen, and P. Westermark 1021 Elevated Vascular Cell Adhesion Molecule-1 in AIDS Encephalitis Induced by Simian Immunodeficiency Virus Vito G. Sasseville, Walter A. Newman, Andrew A Lackner, Mary 0. Smith, Niels C. G. Lausen, Dawson Beall, and DouglasJ. Ringler 1031 Interleukin-4 May Contribute to the Abundant T-cell Reaction and Paucity of Neoplastic B Cells in T-cell-Rich B-cell Lymphomas William R. Macon, John B. Cousar, James A. Waldron, Jr., and Su-Ming Hsu 1037 Synaptophysin Expression in "Ependymal Tumors" Induced by Ethyl-nitrosourea in Rats Jestis Vaquero, Santiago Coca, Mercedes Zurita, Santiago Oya, Alicia Arias, Manuel Moreno, and Carmen Morales Regular Articles 1043 Anti-CD2 Monoclonal Antibodies Prevent Spontaneous and Adoptive Transfer of Diabetes in the BBMWor Rat Avlin K Barlow and Arthur A Like 1053 The Rat Testicular Artery: A Model of Spontaneous Aneurysmal-like Structure Formation Michble Coutard and Mary Osborne-Pellegrin 1063 Multidrug Resistance Gene (P-Glycoprotein) Expression in the Human Fetus Coenraad K van Kalken, Giuseppe Giaccone, Paul van der Valk, Catharina M. Kuiper, Meksi M. N Hadisaputro, Sabina A. A. Bosma, Rik . Scheper, ChrisJ. L. M. Meijer, and Herbert M. Pinedo 1073 Detection of Laminin Receptor mRNA in Human Cancer Cell Lines and Colorectal Tissues by In Situ Hybridization Elias Campo, Carlos Monteagudo, Vincent Castronovo, Anne P. Claysmith, Pedro L. Fernandez, and Mark E. Sobel 1085 Sequential Changes in Histologic Pattern and Extracellular Matrix Deposition During the Healing of Chronic Venous Ulcers S. E. Herrick, P. Sloan, M. McGurk, L. Freak, C N. McCollum, and M. WJ. Ferguson 1097 Characterization of hu-PBL-SCID Mice with High Human Immunoglobulin Serum Levels and Graft-versus-Host Disease Michel A. Duchosal, Sabine A. Eming, Patricia J. McConabey, and FrankJ. Dixon 1115 Differential Permeability of the Blood-Brain Barrier in Experimental Brain Metastases Produced by Human Neoplasms Implanted into Nude Mice Ruo-dan Zhang, Janet E. Price, Takamitsu Fujimaki, Corazon D. Bucana, and Isaiab J. Fidler 1125 Expression of a Chimeric Helix-Loop-Helix Gene, Id-SCL, in K562 Human Leukemic Cells Is Associated with Nuclear Segmentation Adam N Goldfarb, Martin L. Wo/f; andJames M. Greenberg 1139 Transplant Arteriosclerosis in a Rat Aortic Model F. Frank Isik, Thomas 0. McDonald, Marina Ferguson, Elaine Yamanaka, and David Gordon 1151 The Genesis of the Senile Plaque: Further Evidence in Support of its Neuronal Origin M. A. Pappolla, R. A. Omar, K Sambamurti, J. P. Anderson, and N K Robakis 1161 Integrin Distributions in Renal Cell Carcinomas of Various Grades of Malignancy Matti Korhonen, Liisa Laitinen, Jari Ylanne, George K Koukoulis, Vito Quaranta, HarriJuusela, Victor E. Gould, and Ismo Virtanen 1173 Cystitis Induced by Infection with the Lyme Disease Spirochete, Borrelia burgdorferi, in Mice Stephanie Czub, Paul H. Duray, Rex E. Thomas, and Tom G. Schwan 1181 Human Papillomavirus Genomes in Male Urethral Cells G. Della Torre, R. Donghi, P. 0. de Campos Lima, G. Pasquini, S. Pilotti, R. Koronel, M. A. Pierotti, G. De Palo, G. Della Porta, and F. Rilke

1187 Anthracyclines Selectively Decrease ot Cardiac Actin mRNA Abundance in the Rat Heart Thomas Papoian and William Lewis 1197 Efficacy of Monoclonal Antibody Against Human Recombinant Tumor Necrosis Factor in E. co/i-challenged Swine Garyjesmok, Craig Lindsey, Melinda Duerr, Michael Fournel, and Thomas Emerson, Jr. 1209 Epitopes of Human Immunodeficiency Virus Regulatory Proteins tat, nef, and rev Are Expressed in Normal Human Tissue Henk K Parmentier, Dick F van Wichen, Frits H.J. Gmelig Meyling, Jaap Goudsmit, and Henk-Jan Schuurman 1217 Expression of the L2 and E7 Genes of the Human Papillomavirus Type 16 in Female Genital Dysplasias Eeva Auvinen, Harry Kujari, Pertti Arstila, and Veyo Hukkanen 1225 Different Patterns of Macrophage Infiltration into Allogeneic-murine and Xenogeneic-human Neoplasms Growing in Nude Mice Corazon D. Bucana, Angels Fabra, Ricardo Sanchez, and IsaiabJ. Fidler 1237 A Recessive Defect in Lymphocyte or Granulocyte Function Caused by an Integrated Transgene David Lo, Helen Quill, Linda Burkly, Benadette Scott, Richard D. Palmiter, and Ralph L. Brinster 1247 Localization of the Human Cytomegalovirus 2.7-kb Major Early P-gene Transcripts by RNA In Situ Hybridization in Permissive and Nonpermissive Infections Tzyy-Choou Wu, W Anthony Lee, Marie C Pizzorno, Wei-Chun Au, Yu-Jiun Chan, Ralph H. Hruban, Grover M Hutchins, and Gary S. Hayward December 1992 Short Communications 1259 Selective Expression of Sialyl-Lewis X and Lewis A Epitopes, Putative Ligands for L-selectin, on Peripheral Lymph-node High Endothelial Venules Timo Paavonen and Risto Renkonen 1265 Trisomy 12 in Pediatric Granulosa-Stromal Cell Tumors: Demonstration by a Modified Method of Fluorescence In Situ Hybridization on Paraffin-embedded Material DeborahE. Schofield andJonathan A Fletcher 1271 Detection of Replicative Hepatitis C Virus Sequences in Hepatocellular Carcinoma MichaelA. Gerber, Y S. Carol Shieb, Kyu-Sik Shim, Swan N. Thung, A.Jake Demetris, Myron Schwartz, Gulen Akyol, and Srikanta Dash 1279 Interleukin-8: A Corneal Factor That Induces Neovascularization RobertM. Strieter, Steven L. Kunkel, VictorM. Elner, Csaba L. Martonyi, Alisa E. Koch, PeterJ. Polverini, and Susan G. Elner 1285 Growth Fraction in Non-small Cell Lung Cancer Estimated by Proliferating Cell Nuclear Antigen and Comparison with Ki-67 Labeling and DNA Flow Cytometry Data Gabriella Fontanini, Raffaele Pingitore, Daniela Bigini, Silvana Vignati, Stefano Pepe, Angela Ruggiero, and Paolo Macchiarini Regular Articles 1291 Identification of Monoclonal B-cell Populations by Rapid Cycle Polymerase Chain Reaction: A Practical Screening Method for the Detection of Immunoglobulin Gene Rearrangements Glenn H Segal, Carl T Wittwer, AndrewjJ Fishleder, Mark H Stoler, Raymond R. Tubbs, and Carl R. Kjeldsberg 1299 Development and Characterization of an Experimental Model of Brain Abscess in the Rat Nicolaos A. Flaris and William F. Hickey 1309 An Ultrastructural Analysis of Tumor-promoting Phorbol Diester-induced Degranulation of Human Basophils Ann M. Dvorak, Jane A. Warner, Ellen Morgan, Susan Kissell-Rainville, Lawrence M. Lichtenstein, and Donald W MacGlashan, Jr. 1323 Regulated Expression of Vascular Cell Adhesion Molecule-1 in Human Malignant Melanoma NivesJonjic, Ines Martin-Padura, Teresa Pollicino, Sergio Bernasconi, PetrJilek, Aldo Bigotti, Roberta Mortarini, Andrea Anichini, Giorgio Parmiani Francesco Colotta, Elisabetta Dejana, Alberto Mantovani and Pier Giorgio Natali 1331 High-resolution Analyses of Two Different Classes of Tumor Cells In Situ Tagged with Alternative Histochemical Marker Genes Wen-chang Lin, Theresa P. Pretlow, Thomas G. Pretlow II, and Lloyd A. Culp 1343 Immunohistochemical Analysis of p53 Expression in Malignant Lymphomas Jonathan W Said, Raul Barrera, I. Peter Shintaku, H. Nakamura, and H. Phillip Koeffler 1349 Transient Disruptions of Aortic Endothelial Cell Plasma Membranes Q. C. Yu and Paul L. McNeil 1361 Peripheral T-cell Lymphomas of the Intestine Andreas Chott, Brigitte Dragosics, and Thaddaus Radaszkiewicz 1373 Cutaneous Expression of Thy-1 in Mycosis Fungoides David P. Fivenson, Margaret C Douglass, and BrianJ. Nickoloff 1381 Renal Extracellular Matrix Accumulation in Acute Puromycin Aminonucleoside Nephrosis in Rats Colin L. Jones, Shilpa Buch, Martin Post, Lori McCulloch, Elaine Liu, and Allison A. Eddy 1397 Expression of Sialyl-Lewis X, an E-selectin Ligand, in Inflammation, Immune Processes, and Lymphoid Tissues J. Michael Munro, Siu K Lo, Christopher Corless, MichaelJ Robertson, Nina C Lee, Raymond L. Barnhill, David S. Weinberg, and Michael P. Bevilacqua 1409 Changes in Frequency, Morphology, and Behavior of Tumors Induced in Mice by a Polyoma Virus Mutant with a Specifically Altered Oncogene Robert Freund, ClydeJ Dawe, John P. Carroll, and Thomas L. Benjamin 1427 Adhesion Molecules on the Endothelium and Mononuclear Cells in Human Atherosclerotic Lesions Allard C. van der Wal, Pranab K Das, AlbertJ. Tigges, and Anton E. Becker 1435 Induction of Fatty Streak-like Lesions In Vitro Using a Culture Model System Simulating Arterial Intima Takahiro Yamada, Jianglin Fan, Tatsuro Shimokama, Osamu Tokunaga, and Teruo Watanabe 1445 Isolation and Characterization of Granuloma Initiation Factor Maxwell A Fung, Naoyoshi Sato, Toshihiro Iida, Kimie Fukuyama, and William L. Epstein 1453 Estimation of Tumor Growth Fractions in Archival Formalin-fixed, Paraffin-embedded Tissues Using Two Anti-PCNA/Cyclin Monoclonal Antibodies: Factors Affecting Reactivity Arnold B. Gelb, Onsi W Kamel, David P. LeBrun, and Roger A Warnke 1459 Immunohistochemical and Histopathologic Correlates of Alzheimer's Disease-associated Alz-50 Immunoreactivity Quantified in Homogenates of Cerebral Tissue Suzanne M. de la Monte, Rachel A. Spratt, Jonathan Chong, Hossein A. Ghanbarf, andJack R. Wands 1471 Programmed Cell Death in Heterokaryons: A Study of the Transfer of Apoptosis Between Nuclei Bruno Dipasquale and RichardJ. Youle 1481 Changes in Thickness and Anionic Sites of the Glomerular Basement Membrane After Subtotal Nephrectomy in the Rat M P. Dubrulle, F Terzi M C. Gubler, C Kleinknecht, and M Schaeverbeke 1491 Ultrastructural Analysis of Contractile Cell Development in Lung Microvessels in Hyperoxic Pulmonary Hypertension: Fibroblasts and Intermediate Cells Selectively Reorganize Nonmuscular Segments Rosemary Jones 1507 Media Conditioned by Smooth Muscle Cells Cultured in a Variety of Hypoxic Environments Stimulates In Vitro Angiogenesis: A Relationship to Transforming Growth Factor-pl Hitoshi Sakuda, Yutaka Nakashima, Shinichi Kuriyama, and Katsuo Sueishi Animal Model of Human Disease 1517 Pulmonary Cryptococcosis Gary B. Huffnagle and Mary F Lipscomb 1521 Index of Subjects 1529 Index of Authors ACKNOWLEDOGMENT

The Editors gratefully acknowledge the generous assistance of the following reviewers who served between November 1, 1991 and October 15, 1992:

Abul K. Abbas William Carley Harrison W. Farber Barton F. Haynes Arnulf Koeppen Dale R. Abrahamson Frank A. Carone Marilyn Gist Farquhar John T. Headington Nancy Kohl Kenneth B. Adler Stirling Carpenter Anthony Fauci Rogene Henderson Levy Kopelovich Thomas E. Adrian Richard W. Cartun Eric Fearon Gloria H. Heppner Gerri Koopman Bjorn Atzelius Ward Cassells Bruce Fenderson Meenhard Herlyn Leopold G. Koss Steven M. Albelda Tito Cavallo Victor J. Ferrans Steven H. Herrmann Monty Krieger Charles E. Alpers R. S. K. Chaganti Soldano Ferrone Joachim Herz Jeffrey 1. Kreisberg Dario C. Altieri Pierre Chambon Jacob N. Finkelstein Margaret S. Hibbs John Krolewski Ellsworth C. Alvord Gary C. Chamness Kathy Flanders William F. Hickey David J. Krutchkoff Richard F. Ambinder Helen Chan Andrew Flint Nicholas S. Hill Francis P. Kuhajda H. Clarke Anderson Irshad H. Chaudry Stuart C. Flynn Judith S. Hochman Charles Kuhn James M. Anderson Allen W. Cheever Alan M. Fogelman John Holley Steven L. Kunkel Paul Anderson David A. Cheresh Judah Folkman Ian Holt Michael Kurilla Peter G. Anderson Marco Chilosi Kenneth A. Foon William Hook James Kurnick Donald Antonioli Francis V. Chisari Henry Forman Richard L. Hoover David Lagunoff Veena B. Antony Kathleen Cho David A. Fox Dikran S. Horoupian Glen A. Laine Mark L. Armstrong F. Chytil Robert 1. Fox Susan B. Horwitz Mary Ann Lane Frederic B. Askin Richard A. Clark Blas Frangione John Hotchkiss Robert S. Langer Jon Aster Peter G. H. Clarke Wilbur A. Franklin Peter M. Howley James W. Larrick Robert C. Atkins Michael L. Cleary Jeffrey A. Frelinger Ralph H. Hruban David A. Lawrence Burr G. Atkinson Wallace A. Clyde Samuel W. French Sally Ann Huber Juan Lechago Robert Auerbach Alan S. Cohen Henry Friedman Tony E. Hugli Jeffrey Ledbetter Margaret B. Aydelotte Desire Collen Glauco Frizzera Richard L. Humphrey Virginia M-Y. Lee Richard Baer Tucker Collins Philip Frost Phillip M. lannaccone David Leffell Marco Baggiolini Kevin Cooper Robert S. Fujinami Dirk Iglehart Edward J. Leonard Cedric S. Baine Philip H. Cooper Kenneth Fukushi Donald Ingber John Leong Dorothy F. Bainton Carlos Cordon-Cardo Dan Fults Kimishige Ishizaka Jerrold S. Levine Andrew Baird Linda C. Cork Leo T. Furcht Harriet C. Isom Efrat Levy Joseph J. Baldassare Joseph A. Cornicelli Martha B. Furie Bruce S. Jacobson Gary A. Levy William H. Baricos Jeffrey Cossman Heinz Furthmayr Elaine S. Jaffe Dorothy E. Lewis Jane E. Barker John E. Craighead Giulio Gabbiani Eric A. Jaffe Peter Libby Jeffrey L. Barnes Eva B. Cramer James Gailit Joseph S. Janicki Andrew Lichtman Roland Baron John D. Crissman Kazimiera Gajl-Peczalska Andrzej Jarnawski Monica Liebert J. Carl Barrett Bruce N. Cronstein Stephen J. Galli Gilbert Jay Wilfred Lieberthal Brenda E. Barry Edmond C. Crouch Gloria Gallo Diane Jelinek Jeffrey D. Lifson Kenneth W. Barwick Richard Crowell Pierluigi Gambetti Robert Jenkins Boldhard Lindner Steven W. Barthold Christopher P. Crum Charles Ganote Robert B. Jennings Lance A. Liotta Marc Basson Myron Cybulsky Jack Gauldie J. Milburn Jessup Ricardo Lloyd Surinder K. Batra Patricia D'Amore Michael A. Gerber Randy Jirtle Joseph Locker Hector Battifora Morris Dailey A. Martin Gerdes Eugene M. Johnson, Jr. R. A. Lockshin Eugene A. Bauer Marinos C. Dalakas Ross G. Gerrity Judith P. Johnson Daniel S. Longnecker Reuben Baumal Beverly A. Dale Lazaro E. Gerschenson Kent Johnson Martin G. Low Elaine L. Bearer Riccardo Dalla-Favera Godfrey S. Getz Richard J. Johnson Robert B. Low William Beck Ivan Damjanov Joan Gil William W. Johnston Benedict R. Lucchesi Carl G. Becker James L. Daniel Philippe Gillery Robert B. Jones Nick Lukacs Elmer L. Becker James H. Dauber Seymour Glagov Rosemary Jones Francis W. Luscinskas Graeme 1. Bell Darrell Davidson Gerald J. Gleich Manel Jordana Dan Luthringer Jorge L. Benach Jeffrey M. Davidson Leslie Gold Barry M. Kacinski Edward J. Macarak Jeffrey R. Bender Peter Davies Todd Elliot Golde Marshall E. Kadin Joseph A. Madri Earl P. Benditt Harry R. Davis, Jr. Susanne M. Gollin Onsi W. Kamel Ian Magrath Van Bennett Michael A. Davitz Thomas A. Gonwa Agnes B. Kane Adel A. F. Mahmoud Michael P. Bevilacqua Peter J. Dawson Richard Goodman H. Kaneshima Eugene Major June L. Biedler Yogashwar Dayal David Gordon Jie Kang Asrar B. Malik Gregory Biesecker Ronald A. DeLellis Siamon Gordon Yashpal S. Kanwar Normande Marceau Amilo Bignami Vittorio Detendi Avrum Gotlieb Alan Kaplan Rory Marks Darell D. Bigner Achilles A. Demetriou M. Gottesman Gilles Kaplanski George M. Martin Sandra H. Bigner Dennis W. Dickson Victor E. Gould George D. Karpati George R. Martin Timothy Billiar Paul E. DiCorleto Allen M. Gown Michael Kashgarian John Martin Ranjana Bird A-M. Dierick Harvey R. Gralnick William F. Keane Thomas Martin Christine A. Biron A. B. Dodge D. Neil Granger Vicki E. Kelley Antonio Martinez-Hernandez Gail A. Bishop Claire M. Doerschuk Nicholas S. Greenhill Carolyn J. Kelly Martin Marx Sara Bodner Edwin C. Douglass Joel Greenson Scott P. Kennedy David Y. Mason Kim Boekelheide G. Paolo Dotto Joe W. Grisham Robert S. Kerbel Robert J. Mason Karl Bomsztyk Kevin Driscoll Thomas M. Grogan Scott Kern Colin L. Masters Eduardo Bonilla R. A. Dubin P. Gruppuso H. Kim Lynn M. Matrisian Wayne A. Border Michel A. Duchosal Marina 1. Gutierrez Gary T. Kinasewitz James Mauer Dov L. Boros Ann M. Dvorak Martin Haas Jean-Pierre Kinet Charles E. McCall Mario A. Bourdon Harold F. Dvorak Daniel Haber Richard J. King James McCarthy Daniel Bowen-Pope Walter Eckhart Rodger C. Haggitt Michael G. Kinsella John L. McClellan Laurence A. Boxer Richard L. Edelson Steven 1. Hajdu Thomas J. Kipps Rod McComb Douglas Brash Thomas S. Edgington Katherine A. Hajjar C. James Kirkpatrick Cahir McDevitt Jonathan Braun Pamela Edmonds Phillip F. Halloran Takashi Kishimoto James K. McDougall Lundy Braun Garth Ehrlich Stanley R. Hamilton R. Kisilevsky Timothy McKeithan Rodrigo Bravo Richard Eisen Robert E. Hammer Geoffrey Kitchingman Barbara J. McLaughlin Philip Browning J. T. Elder Elizabeth H. Hammond Michael Klagsbrun Bruce M. McManus Michael J. Buchmeier Jack A. Elias Curtis Hanson Saulo Klahr Linda M. McManus Patrick J. Buckley Steven N. Emancipator Goran K. Hansson George Klein L. Jeffrey Medeiros L. Maximillian Buja Gerda Endemann James Harper Michael Klein Daniel Medina Randall Burt Eva Engvall Curtis C. Harris A. Klein-Szanto Alexander Meissels Eugene C. Butcher Barbara Ensoli Edward Harris David S. Klimstra Myron R. Melamed Ralph Buttyan Robert A. Erlandson Nancy L. Harris Daniel M. Knowles George Melnykovych Philip Cagle Yener S. Erozan Steven A. Harris Warren Knudson Paul Meltzer Pasquale A. Cancilla Jeffrey Everitt Mark E. Haskins K. Kobayashi Stephen J. Meltzer Charles C. Capen Joseph C. Fantone Ingeborg Hauser Alisa E. Koch H. Mena Geoffrey Mendelsohn Paul K. Pattengale Barrett J. Rollins David Sidransky Raymond Tubbs Maria J. Merino Donald Payan Olga Ronnekleiv Norman J. Siegel Benjamin Tycko Glenn Merlino Angel Pellicer Richard M. Rose Mark Siegelman Mark L. Tykocinski June Rae Merwin Qian Peng Seymour Rosen Anders A. F. Sima David S. Ucker Albee Messing Neal S. Penneys Steven D. Rosen Richard L. Simmons Thomas R. Ulich Barbara Meyrick George Perry Russell Ross Jean Simpson Axel Ullrich Alfred F. Michael David H. Persing Robert Rothlein Alphonse E. Sirica Koichi Uyemura Markku Miettinen Manuel Perucho Sharon Rounds Jeffrey L. Sklar Jan Vaage Silvia Miotti Sem H. Phan Robert Rouse Dennis Slamon Harry Van Goor Fred R. Miller Kent E. Pinkerton Wolfram Ruf Bonnie F. Sloane James Varani Gary J. Miller Henry C. Pitot Bruce Ruggeri Brian Smith Manjeri A. Venkatachalam Si-Chun Ming Jeffrey L. Platt Una S. Ryan C. Wayne Smith Gregory Vercellotti John D. Minna Jordan S. Pober Jonathan W. Said Nour Sneige Ellen S. Vitetta Mack Mitchell Daniel K. Podolsky D. J. Salant Mark E. Sobel Bert Vogelstein Benjamin Mitmaker Thomas J. Podor Avery A. Sandberg Raymond A. Sobel Eric Vonderheid Johan Moan Bruce Ponder Eric P. Sandgren Enrico Solcia Franz C. von Lichtenberg Irvin Modlin Henry C. Powell David C. Sane Michael Solursh Denisa D. Wagner Roland Moll Stephen M. Prescott Daniel Santa Cruz Philip Spagnuolo Sharon Wahl Edward L. Morgan Thomas G. Pretlow Balfour Sartor Robert Spengler Cheryl L. Walker David A. Moscatelli Donald L. Price Carl Saxinger Samuel S. Spicer Kenneth A. Walsh Marsha A. Moses Jean H. Priest Thomas Schall Michael Sporn Peter A. Ward Deane F. Mosher Gail Prins Berndt Scheithauer Glenn A. Steele, Jr. Michael J. Wargovich Mary Pat Moyer Stanley B. Prusiner Raymond R. Schleef Lawrence Steinman Roger A. Warnke Elliott Mufson William A. Pryor Richard C. Schlegel Michael B. Stemerman E. A. Wayner William A. Muller William C. Pugh Richard Schlesinger David M. Stern Dennis D. Weisenburger Mary J. Murnane David T. Purtilo* Jeffrey Schlom William Stetler-Stevenson L. Leonard Weiss Ruth J. Muschel Reed Pyeritz James W. Schmidley Mark H. Stoler Lawrence M. Weiss Lee Nadler Robert Pytela Eveline E. Schneeberger Gary D. Stoner Stephen J. Weiss Ray B. Nagle S. Qualman Frederick J. Schoen Richard Straight Zena Werb H. Nakatani Andrea Quaroni Colin J. Schwartz Mette Strand A. Brian West Opendra Narayan Alex Rabinovitch Melvin M. Schwartz James A. Strauchen Janice Wherry Arthur H. Neufeld Marlene Rabinovitch Jean E. Schwarzbauer J. Wayne Streilein Theresa L. Whiteside Walter Newman Arnold B. Rabson Dawn Schwenke Gary E. Striker Max S. Wicha Brian J. Nickoloff Lorraine Racusen John H. Sedor Mark Sumi Thomas N. Wight Roberto F. Nicosia Mark Raffeld Steven S. Segal B. Sumpio Ronald L. Wilder Marcel Nimni Elaine W. Raines Pravin Sehgal F. William Sunderman, Jr. Mark C. Willingham Ralph Nixon Ahmed Rasheed Michael Seiden Fabrizio Tagliavini Cheryl Willman Sigurd J. Normann Lee Ratner Dennis Selkoe Margaret A. Tempero Curtis B. Wilson Gabriel Nunez Matthew M. Rechler Kenneth W. Sell Robert D. Terry Robert K. Winn Gerard J. Nuovo Janardan K. Reddy Ranjan Sen Francis T. Thomas Henry Wisniewski Terry D. Oberley Raymond W. Redline Donald A. Sens Nancy Thompson Robert W. Wissler G. Richard Olds John Reed Alex Sevanian Ann D. Thor Peter Witschi Eric N. Olson Michael A. Reidy Keerti Shah Snorri S. Thorgeirsson Albert Wong Jean L. Olson Daniel G. Remick M. Refaat Shalaby Robert E. Tigelaar Grace Wong Joost J. Oppenheim Helmut Rennke Abulkalam Shamsuddin Gerd 0. Till Gary S. Wood Jan M. Orenstein Catherine Reznikoff P. R. Shank Martin Tobi Craig D. Woodworth Jacqueline M. Orian James G. Rheinwald Paul Shanley N. Tomosugi Priscilla B. Wyrick Laurlee Osborn Jerry M. Rice Michael Shasby Robert L. Trelstad John H. Yardley Mary Osborn John B. Richardson Cheng-Mei Shaw Jeffrey M. Trent Raymond Yesner Ivan G. Otterness A. B. Rickinson Michael L. Shelanski Timothy J. Triche Steven G. Younkin Gary K. Owens David J. Riley Virginia L. Shepherd John 0. Trojanowski Peter D. Yurchenco George Owens Stanley Robboy F. Alan Sher John Trowsdale Sherif R. Zaki Michael J. Pabst Anita Roberts Darryl Shibata Dean A. Troyer Bruce R. Zetter Judith L. Pace Moses Rodriguez Yoji Shimizu Lawrence D. True Ellen Zimmerman David L. Page Joseph Rogers Toshimichi Shimohara Benjamin F. Trump Dorothea Zucker-Franklin Mark S. Paller Charles Rogler Stephen B. Shohet Ming-Sound Tsao Mary M. Zutter Gary R. Pasternack Marcos Rojkind Howard M. Shulman Tai-Lan Tuan Nathan J. Zvaifler * Deceased INFORMATION FOR AUTHORS (Revised July, 1992)

Scope Manuscript Submission THE AMERICAN JOURNAL OF PATHOLOGY, the Five copies of the manuscript and four sets of official journal of the American Association of Pa- figures should be addressed to: thologists, seeks to publish high-quality original Nelson Fausto, MD papers on mechanisms of disease. Editor-in-Chief We accept manuscripts that report important The American Journal of Pathology findings on disease pathogenesis or basic biolog- 9650 Rockville Pike ical mechanisms that relate to disease, without Bethesda, MD 20814-3993 preference for a specific method of analysis. High priority is given to studies on human disease and A cover letter giving the full name, address, relevant experimental models that use cellular, telephone, and fax numbers of the corresponding molecular, biochemical, and immunological ap- author must accompany each manuscript. Upon proaches in conjunction with morphology, and to receipt, a letter of acknowledgment assigning a manuscripts that report the development of new number to the manuscript will be sent to the cor- molecular probes and their application in studies responding author. This number should be used of disease pathogenesis and diagnosis. in all communications with the editorial office. Revised manuscripts should be submitted within 6 months from the date of the letter of disposition. Manuscript Categories Revisions submitted after this deadline will be renumbered and sent out for review de novo. In addition to regular papers, the journal pub- lishes Short Communications, a category in- Copyright. In accordance with The Copyright tended to provide a mechanism for the rapid pub- Revision Act of 1976, a copyright assignment form lication of timely and significant findings. Manu- will be mailed with the letter of acknowledgment scripts in this category should be concise but to the corresponding author, who should sign it definitive and must not exceed five printed pages on behalf of all co-authors and return it to the in length, including abstract, text, references, ta- editorial office. The copyright assignment has no bles, and figures (approximately 2000 words of legal effect if the manuscript is not accepted for text and a maximum of three figures). Papers sub- publication. mitted as Short Communications should follow Publication Statement. The copyright assign- the guidelines for the preparation of regular arti- ment form also includes a publication statement cles. The Materials and Methods section should affirming that the material submitted is original; be condensed but must be presented in sufficient that it has not been reported previously (other detail to permit evaluation by reviewers and repro- than in abstract form), and is not under consider- duction of experiments by other scientists. ation for publication elsewhere; that the material Reviews, editorial comment, and papers in a has been approved for submission for publication series entitled "Methods and Models for the Anal- by all the authors; and that persons cited for un- ysis of Disease Mechanisms," are generally so- published work have approved such citation. The licited by the Editor-in-Chief. Authors interested corresponding author will sign on behalf of all in submitting manuscripts under these headings co-authors. should consult with the Editor-in-Chief. Page Charges. There is a page charge of $40.00 per printed page. If an author is unable to pay this The Review Process charge, the reason should be stated in the letter of submission. Inability to pay will not influence ed- Manuscripts received by the Editor-in-Chief are itorial decisions. assigned to the Associate Editors according to their particular area of expertise. The reviews from the referees and the comments of the Asso- Manuscript Preparation ciate Editors are forwarded to the Editor-in-Chief Manuscripts should be prepared in the style of the for disposition and transmittal to the authors. We journal and in accordance with The Uniform Re- try to complete the review process in 45 days for quirements for Manuscripts Submitted to Bio- regular papers and within 2 to 3 weeks for Short medical Journals (see N Engl J Med, 1991, 324: Communications. 424-428). Standard abbreviations will be found in The corresponding author may identify four or the CBE Style Manual (5th ed., 1983). Papers five potential reviewers when submitting the should be typed double-spaced throughout (in- manuscript. cluding references, tables, and figure legends)

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