CDH15 monoclonal antibody, clone Storage Instruction: Store at 4°C on dry atmosphere. 21G4 After reconstitution with deionized water, store at -20°C or lower. Catalog Number: MAB3922 Aliquot to avoid repeated freezing and thawing.

Regulatory Status: For research use only (RUO) GeneID: 1013

Product Description: Mouse monoclonal antibody Symbol: CDH15 raised against partial recombinant CDH15. Gene Alias: CDH14, CDH3, CDHM, MCAD Clone Name: 21G4 Gene Summary: This gene is a member of the Immunogen: Recombinant corresponding to superfamily of , encoding calcium-dependent extracellular region of human CDH15. intercellular adhesion . consist of an extracellular domain containing 5 cadherin Host: Mouse domains, a transmembrane region, and a conserved cytoplasmic domain. Transcripts from this particular Reactivity: Human cadherin are expressed in myoblasts and upregulated in myotubule-forming cells. The protein is thought to be Applications: EIA, IF, WB-Tr essential for the control of morphogenetic processes, (See our web site product page for detailed applications specifically myogenesis, and may provide a trigger for information) terminal muscle cell differentiation. [provided by RefSeq]

Protocols: See our web site at http://www.abnova.com/support/protocols.asp or product page for detailed protocols

Specificity: Cadherins are a family of transmembrane glycoproteins that play a key role in Calcium dependent cell-. Several members of the cadherin family have been identified so far, including E- (epithelial), P- (placental), N- (neuronal) and M- (muscle) cadherin. M-Cadherin is expressed in myoblasts and might be involved in skeletal muscle cell differentiation. Does not cross-react with mouse.

Form: Lyophilized

Isotype: IgG1

Recommend Usage: ELISA (0.05 ug/mL) Western Blot (1 ug/mL for AP/BCIP/NBT (MTT) detection 0.5 ug/mL for HRP/ECL detection) Immunofluorescence (5 ug/mL) The optimal working dilution should be determined by the end user.

Storage Buffer: Lyophilized from 2x PBS (PEG, sucrose, 0.09% sodium azide)

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