Annual Report 2013
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UNITED STATES SECURITIES and EXCHANGE COMMISSION Washington, D.C
UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 2)* GENOCEA BIOSCIENCES, INC. (Name of Issuer) Common Stock, Par Value $0.001 (Title of Class of Securities) 372427 10 4 (CUSIP Number) Victoria A. Whyte GlaxoSmithKline plc 980 Great West Road Brentford, Middlesex TW8 9GS England Telephone: +44 (0)208 047 5000 Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications) July 30, 2015 (Date of Event which Requires Filing of this Statement) If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box. ☐ Note: Schedules filed in paper format shall include a signed original and five copies of the schedule, including all exhibits. See Rule.13d-7 for other parties to whom copies are to be sent. * The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page. The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes). -
Corporate Governance
Strategic report Governance and remuneration Financial statements Investor information Corporate Governance In this section Chairman’s Governance statement 78 The Board 80 Corporate Executive Team 83 Board architecture 85 Board roles and responsibilities 86 Board activity and principal decisions 87 Our purpose, values and culture 90 The Board’s approach to engagement 91 Board performance 94 Board Committee information 96 Our Board Committee reports 97 Section 172 statement 108 Directors’ report 109 GSK Annual Report 2020 77 Chairman’s Governance statement In last year’s Governance statement, I explained that our primary Education and focus on Science objective for 2020 was to ensure there was clarity between the Given the critical importance of strengthening the pipeline, Board and management on GSK’s execution of strategy and its the Board has benefitted from devoting a higher proportion of operational priorities. We have aligned our long-term priorities its time in understanding the science behind our strategy and of Innovation, Performance and Trust powered by culture testing its application. It is important that the Board has a and agreed on the metrics to measure delivery against them. working understanding of the key strategic themes upon The Board’s annual cycle of meetings ensures that all major which our R&D strategy is based. These themes have been components of our strategy are reviewed over the course complemented by Board R&D science thematic deep dives. of the year. Our focus was on the fundamentals of our strategy: human The COVID-19 pandemic impacted and dominated all our genetics, the immune system and AI and ML, as well as to lives for the majority of 2020. -
DENTIN HYPERSENSITIVITY: Consensus-Based Recommendations for the Diagnosis & Management of Dentin Hypersensitivity
October 2008 | Volume 4, Number 9 (Special Issue) DENTIN HYPERSENSITIVITY: Consensus-Based Recommendations for the Diagnosis & Management of Dentin Hypersensitivity A Supplement to InsideDentistry® Published by AEGISPublications,LLC © 2008 PUBLISHER Inside Dentistry® and De ntin Hypersensitivity: Consensus-Based Recommendations AEGIS Publications, LLC for the Diagnosis & Management of Dentin Hypersensitivity are published by AEGIS Publications, LLC. EDITORS Lisa Neuman Copyright © 2008 by AEGIS Publications, LLC. Justin Romano All rights reserved under United States, International and Pan-American Copyright Conventions. No part of this publication may be reproduced, stored in a PRODUCTION/DESIGN Claire Novo retrieval system or transmitted in any form or by any means without prior written permission from the publisher. The views and opinions expressed in the articles appearing in this publication are those of the author(s) and do not necessarily reflect the views or opinions of the editors, the editorial board, or the publisher. As a matter of policy, the editors, the editorial board, the publisher, and the university affiliate do not endorse any prod- ucts, medical techniques, or diagnoses, and publication of any material in this jour- nal should not be construed as such an endorsement. PHOTOCOPY PERMISSIONS POLICY: This publication is registered with Copyright Clearance Center (CCC), Inc., 222 Rosewood Drive, Danvers, MA 01923. Permission is granted for photocopying of specified articles provided the base fee is paid directly to CCC. WARNING: Reading this supplement, Dentin Hypersensitivity: Consensus-Based Recommendations for the Diagnosis & Management of Dentin Hypersensitivity PRESIDENT / CEO does not necessarily qualify you to integrate new techniques or procedures into your practice. AEGIS Publications expects its readers to rely on their judgment Daniel W. -
Governance and Remuneration 2014
Governance & remuneration reportStrategic In this section Our Board 72 Our Corporate Executive Team 76 Chairman’s letter 78 Corporate governance framework 79 Board report to shareholders Oversight and stewardship in 2014 and future actions 80 remuneration & Governance Leadership and effectiveness 82 Committee reports Audit & Risk 86 Nominations 92 Corporate Responsibility 94 Remuneration report Chairman’s annual statement 96 Annual report on remuneration 97 2014 Remuneration policy report 119 Financial statements Financial Investor information Investor GSK Annual Report 2014 71 Our Board Strategic reportStrategic Diversity Experience International experience Composition Tenure (Non-Executives) % % % % Scientific 19 Global 75 Executive 19 Up to 3 years 39 % % % % Finance 31 USA 100 Non-Executive 81 3-6 years 15 % % % % Industry 50 Europe 94 Male 69 7-9 years 23 % % % EMAP 63 Female 31 Over 9 years 23 Sir Christopher Gent 66 Skills and experience Chairman Sir Christopher has many years of experience of leading global businesses and a track record of delivering outstanding performance Governance & remuneration & Governance Nationality in highly competitive industries. He was appointed Managing Director British of Vodafone plc in 1985 and then became its Chief Executive Officer Appointment date in 1997 until his retirement in 2003. Sir Christopher was also a 1 June 2004 and as Chairman Non-Executive Director of Ferrari SpA and a member of the British on 1 January 2005 Airways International Business Advisory Board. Committee membership External appointments Corporate Responsibility Sir Christopher is a Senior Adviser at Bain & Co. Committee Chairman, Nominations, Remuneration and Finance Sir Philip Hampton 61 Skills and experience Chairman Designate Prior to joining GSK, Sir Philip chaired major FTSE 100 companies including J Sainsbury plc. -
Annual Report and Accounts 2019
IMPERIAL BRANDS PLC BRANDS IMPERIAL ANNUAL REPORT AND ACCOUNTS 2019 ACCOUNTS AND REPORT ANNUAL ANNUAL REPORT AND ACCOUNTS 2019 OUR PURPOSE WE CAN I OWN Our purpose is to create something Everything See it, seize it, is possible, make it happen better for the world’s smokers with together we win our portfolio of high quality next generation and tobacco products. In doing so we are transforming WE SURPRISE I AM our business and strengthening New thinking, My contribution new actions, counts, think free, our sustainability and value creation. exceed what’s speak free, act possible with integrity OUR VALUES Our values express who we are and WE ENJOY I ENGAGE capture the behaviours we expect Thrive on Listen, challenge, share, make from everyone who works for us. make it fun connections The following table constitutes our Non-Financial Information Statement in compliance with Sections 414CA and 414CB of the Companies Act 2006. The information listed is incorporated by cross-reference. Additional Non-Financial Information is also available on our website www.imperialbrands.com. Policies and standards which Information necessary to understand our business Page Reporting requirement govern our approach1 and its impact, policy due diligence and outcomes reference Environmental matters • Occupational health, safety and Environmental targets 21 environmental policy and framework • Sustainable tobacco programme International management systems 21 Climate and energy 21 Reducing waste 19 Sustainable tobacco supply 20 Supporting wood sustainability -
Oral Diagnosis: the Clinician's Guide
Wright An imprint of Elsevier Science Limited Robert Stevenson House, 1-3 Baxter's Place, Leith Walk, Edinburgh EH I 3AF First published :WOO Reprinted 2002. 238 7X69. fax: (+ 1) 215 238 2239, e-mail: [email protected]. You may also complete your request on-line via the Elsevier Science homepage (http://www.elsevier.com). by selecting'Customer Support' and then 'Obtaining Permissions·. British Library Cataloguing in Publication Data A catalogue record for this book is available from the British Library Library of Congress Cataloging in Publication Data A catalog record for this book is available from the Library of Congress ISBN 0 7236 1040 I _ your source for books. journals and multimedia in the health sciences www.elsevierhealth.com Composition by Scribe Design, Gillingham, Kent Printed and bound in China Contents Preface vii Acknowledgements ix 1 The challenge of diagnosis 1 2 The history 4 3 Examination 11 4 Diagnostic tests 33 5 Pain of dental origin 71 6 Pain of non-dental origin 99 7 Trauma 124 8 Infection 140 9 Cysts 160 10 Ulcers 185 11 White patches 210 12 Bumps, lumps and swellings 226 13 Oral changes in systemic disease 263 14 Oral consequences of medication 290 Index 299 Preface The foundation of any form of successful treatment is accurate diagnosis. Though scientifically based, dentistry is also an art. This is evident in the provision of operative dental care and also in the diagnosis of oral and dental diseases. While diagnostic skills will be developed and enhanced by experience, it is essential that every prospective dentist is taught how to develop a structured and comprehensive approach to oral diagnosis. -
Glaxosmithkline Bangladesh Limited (GSK)
GlaxoSmithKline Bangladesh Limited (GSK) Recruitment and Selection Process of GlaxoSmithKline Bangladesh Limited: An Evaluation nd Date of Submission: 2 September, 2014 ©Daffodil International University DAFFODIL INTERNATIONAL UNIVERSITY Internship Report On Recruitment and Selection Process of GlaxoSmithKline Bangladesh Limited: An Evaluation Submitted To Dr. Zakir Hossain Dean& Professor Faculty of Business & Economics Daffodil International University Submitted By Ishrat Jahan ID: 131-14-1019 Masters of Business Administration Daffodil International University Date of Submission: 2nd September, 2014 ©Daffodil International University Letter of Transmittal September 2, 2014 To Dr. Zakir Hossain Dean & Professor Faculty of Business and Economics Daffodil International University Dhaka-1205 Subject: Submission of internship report on recruitment and selection process: An evaluation of GlaxoSmithKline Bangladesh Limited Sir, I am highly satisfied to submit my report on recruitment and selection process: an evaluation of GSK. For preparing this report I tried my best to accumulate relevant and upgraded information from available sources. In preparing this report, I tried my level best to make it a complete one and sincerely look forward to any possible correction. I am very glad because you also given the opportunity to prepare this report .I hope that this report will meet the standards of your judgments. Your Sincerely ---------------- Ishrat Jahan ©Daffodil International University i Certificate of the Supervisor This is to certify that the internship report titled ―Recruitment and Selection Process of GlaxoSmithKline Bangladesh Limited: An Evaluation‖, has been prepared by Ms. Ishrat Jahan bearing ID: 131-14-1019 under my supervision, a practical study on GlaxoSmithKline Bangladesh Limited. I think on the basic of declaration Ms. -
British American Tobacco's Submission to the WHO's
British American Tobacco’s submission to the WHO’s Framework Convention on Tobacco Control This is the submission of the British American Tobacco group of companies commenting on the WHO’s Framework Convention on Tobacco Control. We are the world’s most international tobacco group with an active presence in 180 countries. Our companies sell some of the world’s best known brands including Dunhill, Kent, State Express 555, Lucky Strike, Benson & Hedges, Rothmans and Pall Mall. Executive summary • The WHO’s proposed ‘Framework Convention on Tobacco Control’ is fundamentally flawed and will not achieve its objectives. • The tobacco industry, along with other industries involved in the manufacture and distribution of legal but risky products, is the subject of considerable public attention. It is important that the debate about tobacco remains open, objective, constructive and free from opportunistic criticism if we are effectively to address the real issues associated with tobacco. • British American Tobacco is responsible tobacco. We seek to operate in partnership with governments, who are significant stakeholders in our business, and other interested parties, based on our open acknowledgement that we make a risky product and therefore support sensible regulation. • British American Tobacco shares the World Health Organisation’s desire to reduce the health impact of tobacco use. This paper outlines British American Tobacco’s proposal for the sensible regulation of tobacco. • Our proposal will relieve the WHO of the cost and bureaucracy involved in its wish to become a single global tobacco regulator, leaving it free to do what it should be doing – policy orientation. Some facts about tobacco • Today over one billion adults, about one third of the world’s adult population, choose to smoke. -
Companies Subject to Exclusion
Opdateret 01-08-2021 Vellivs Ekslusionsliste Velliv ønsker ikke at investere i selskaber, som bryder med Vellivs ESG-kriterier fastlagt i politikken for ansvarlig investering og aktivt ejerskab og som ikke udviser forandringsvilje i forhold til deres håndtering af ESG-risici. Endelig ønsker Velliv ikke at investere i tobaksselselskaber, selskaber med aktivteter i kontroversielle våben eller selskaber, hvor mere end 5 pct. af omsætningen stammer fra udvinding af kul og oliesand. Selsakb Kommentar 22nd Century Group, Inc. Tobacco AECOM Contr.Weapons Aerojet Rocketdyne Holdings, Inc. Contr.Weapons Aerojet Rocketdyne, Inc. Contr.Weapons Aeroteh SA Contr.Weapons Airbus SE Contr.Weapons Al-Eqbal Co. for Investment Plc Tobacco ALLETE, Inc. Kul Alliance Holdings GP LP Coal Alliance Resource Operating Partners LP Coal Alliance Resource Partners LP Coal Alpha Metallurgical Resources, Inc Coal Alpha Natural Resources Inc Coal Altadis Emisiones Financieras SA Tobacco Altadis SA Tobacco AltaGas Ltd. Gas/ESG Altius Minerals Corporation Coal Altria Group, Inc. Tobacco Anglo American plc Kul Anglo Pacific Group plc Coal Arch Resources, Inc. Coal Arcis Resources Corp. Tobacco Aryt Industries Ltd. Contr.Weapons Asenovgrad Tabac AD Tobacco Ashtrom Group Ltd. Normviolation>human rights Athabasca Oil Corporation Oilsand Avco Corp. Contr.Weapons B.A.T. Capital Corp. Tobacco B.A.T. Finance BV Tobacco B.A.T. International Finance Plc Tobacco Babcock International Group plc Contr.Weapons BADECO ADRIA dd Tobacco BAE Systems (Finance) Ltd. Contr.Weapons BAE Systems plc Contr.Weapons Bat Brasil Tobacco Bathurst Resources Limited Coal Baytex Energy (LP) Ltd. Oilsand Baytex Energy Corp. Oilsand Bellatora, Inc. Tobacco BHP Group Limited Kul BHP Group Plc Kul BlackPearl Resources, Inc. -
Restrictive Diets and Oral Health What Youdo Need to Iknow Need to Floss?
spring/summerwinter 20172018 Vegan Gluten Free Lactose Free Restrictive Diets and Oral Health What YouDo Need to IKnow Need to Floss? PLEASEPLEASE DO DO NOT NOT REMOVE REMOVE FROM FROM RECEPTION RECEPTION AREA. AREA. VisitVisit usus onlineonline youroralhealth.cayouroralhealth.ca A valuable resource for your patients. BROUGHT TO YOU BY THE ONTARIO DENTAL ASSOCIATION CONTENTS Winter 2018 4 WELCOME Publisher Dr. Deborah Saunders Marcus Staviss Editor-In-Chief Dr. Deborah Saunders 5 OUR CONTRIBUTORS Consulting Editor 6 Dr. Ian McConnachie 6 VITAMINS, MINERALS AND NUTRIENTS Editor The impact of restrictive diets Julia Kuipers on your oral health. Creative and Graphic Design Specialist Catherine Solmes Natalia Ivashchenko Graphic Designer SIT TIGHT Ananya Bhattasali 9 The dental chair through the ages. Policy Editor Roberta MacLean Catherine Morana Copy Editor and Proofreader Jennifer D. Foster 12 IMMUNE SYSTEM DISORDERS And their effects on your oral health. Advisory Board 12 President, ODA Bonnie Dean Dr. LouAnn Visconti President-Elect, ODA 14 ASK YOUR DENTIST! Dr. David Stevenson Questions dentists want you to ask about oral health. Vice-President, ODA Donna Paris Dr. Kim Hansen Past-President, ODA 18 DORM DENTAL DANGERS Dr. Jack McLister Why a toothache should never be part of the curriculum. Advertising For more information about advertising or sponsorship Maggie Blood opportunities for YourOralHealth.ca Brought to You by the 18 ODA, please contact Jennifer DiIorio or Gillian Thomas at Dovetail Communications at 905-886-6640 or 20 ORAL MAXILLOFACIAL [email protected] or [email protected]. REHABILITATION PROGRAM Rehabilitating patients from the inside out. Disclaimer The publication of an article or advertisement Sophie Lamoureux should not be construed as an endorsement of or approval by the ODA. -
Zebrafish Behavioral Profiling Links Drugs to Biological Targets and Rest/Wake Regulation
www.sciencemag.org/cgi/content/full/327/5963/348/DC1 Supporting Online Material for Zebrafish Behavioral Profiling Links Drugs to Biological Targets and Rest/Wake Regulation Jason Rihel,* David A. Prober, Anthony Arvanites, Kelvin Lam, Steven Zimmerman, Sumin Jang, Stephen J. Haggarty, David Kokel, Lee L. Rubin, Randall T. Peterson, Alexander F. Schier* *To whom correspondence should be addressed. E-mail: [email protected] (A.F.S.); [email protected] (J.R.) Published 15 January 2010, Science 327, 348 (2010) DOI: 10.1126/science.1183090 This PDF file includes: Materials and Methods SOM Text Figs. S1 to S18 Table S1 References Supporting Online Material Table of Contents Materials and Methods, pages 2-4 Supplemental Text 1-7, pages 5-10 Text 1. Psychotropic Drug Discovery, page 5 Text 2. Dose, pages 5-6 Text 3. Therapeutic Classes of Drugs Induce Correlated Behaviors, page 6 Text 4. Polypharmacology, pages 6-7 Text 5. Pharmacological Conservation, pages 7-9 Text 6. Non-overlapping Regulation of Rest/Wake States, page 9 Text 7. High Throughput Behavioral Screening in Practice, page 10 Supplemental Figure Legends, pages 11-14 Figure S1. Expanded hierarchical clustering analysis, pages 15-18 Figure S2. Hierarchical and k-means clustering yield similar cluster architectures, page 19 Figure S3. Expanded k-means clustergram, pages 20-23 Figure S4. Behavioral fingerprints are stable across a range of doses, page 24 Figure S5. Compounds that share biological targets have highly correlated behavioral fingerprints, page 25 Figure S6. Examples of compounds that share biological targets and/or structural similarity that give similar behavioral profiles, page 26 Figure S7. -
Annual Review 2005
GS2184_Review_A\W2.qxd 7/3/06 4:58 pm Page fc1 Annual Review 2005 human being Do more, feel better, live longer GS2184_Review_A\W2.qxd 9/3/06 1:28 pm Page ifc2 01 An interview with Sir Christopher Gent, Chairman, and JP Garnier, Chief Executive Officer 05 Tachi Yamada, Chairman, Research & Development, Pharmaceuticals 06 Jean Stéphenne, President and General Manager, GSK Biologicals 08 John Clarke, President, Consumer Healthcare 11 David Stout, President, Pharmaceutical Operations 14 Performance highlights 15 Business operating review 18 The Board 19 The Corporate Executive Team 20 Summary remuneration report 23 Corporate governance 24 Responsibility statements 25 Summary financial statements 26 Summary information under US GAAP 27 Shareholder information 29 Chairman and CEO’s closing letter JP Garnier (left) and Sir Christopher Gent (right) GS2184_Review_A\W2.qxd 7/3/06 5:01 pm Page 01 “Discovering important medicines, eradicating diseases, improving the quality of people’s lives and making medicines available to a greater number of people. This is what we do – and what we do matters to people.” JP Garnier, Chief Executive Officer An interview with Sir Christopher Gent, Chairman and JP Garnier, Chief Executive Officer 2005: a year of success and progress “Thanks to the efforts of our employees around the company’s pipeline is one of the largest and most world, 2005 was a very successful year for GSK,” says promising in the industry, with 149 projects in clinical JP Garnier, Chief Executive Officer. “Not only was it development (as at the end of February 2006), our best year ever from a financial standpoint, we also including 95 new chemical entities (NCEs), 29 product made substantial progress with our pipeline of line extensions (PLEs) and 25 vaccines.