A Case Study of Glaxosmithkline Plc )
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Glaxosmithkline Bangladesh Limited (GSK)
GlaxoSmithKline Bangladesh Limited (GSK) Recruitment and Selection Process of GlaxoSmithKline Bangladesh Limited: An Evaluation nd Date of Submission: 2 September, 2014 ©Daffodil International University DAFFODIL INTERNATIONAL UNIVERSITY Internship Report On Recruitment and Selection Process of GlaxoSmithKline Bangladesh Limited: An Evaluation Submitted To Dr. Zakir Hossain Dean& Professor Faculty of Business & Economics Daffodil International University Submitted By Ishrat Jahan ID: 131-14-1019 Masters of Business Administration Daffodil International University Date of Submission: 2nd September, 2014 ©Daffodil International University Letter of Transmittal September 2, 2014 To Dr. Zakir Hossain Dean & Professor Faculty of Business and Economics Daffodil International University Dhaka-1205 Subject: Submission of internship report on recruitment and selection process: An evaluation of GlaxoSmithKline Bangladesh Limited Sir, I am highly satisfied to submit my report on recruitment and selection process: an evaluation of GSK. For preparing this report I tried my best to accumulate relevant and upgraded information from available sources. In preparing this report, I tried my level best to make it a complete one and sincerely look forward to any possible correction. I am very glad because you also given the opportunity to prepare this report .I hope that this report will meet the standards of your judgments. Your Sincerely ---------------- Ishrat Jahan ©Daffodil International University i Certificate of the Supervisor This is to certify that the internship report titled ―Recruitment and Selection Process of GlaxoSmithKline Bangladesh Limited: An Evaluation‖, has been prepared by Ms. Ishrat Jahan bearing ID: 131-14-1019 under my supervision, a practical study on GlaxoSmithKline Bangladesh Limited. I think on the basic of declaration Ms. -
EMJ-5.2-2020-4.Pdf
Contents + EDITORIAL BOARD 4 + CONGRESS REVIEW Review of the European Conference on Rare Diseases, 10 15th – 16th May 2020 + FEATURE The COVID-19 Conundrum and Cancer – Making Perfect Sense of 19 Imperfect Data Utkarsh Acharya + SYMPOSIUM REVIEW Early Intervention with Anti-Tumour Necrosis Factor in Ulcerative 22 Colitis: The Missing Piece of The Puzzle? + POSTER REVIEWS Eicosapentaenoic Acid: Atheroprotective Properties and the Reduction 29 of Atherosclerotic Cardiovascular Disease Events Chlormethine Gel for Mycosis Fungoides T-cell Lymphoma: Recent 37 Real-World Data + INTERVIEWS Data from the AUGUSTUS Trial Adds an Important Piece to the 42 Complex Puzzle of Antithrombotic Treatment for Those with Nonvalvular Atrial Fibrillation with Acute Coronary Syndrome and/or Percutaneous Coronary Intervention Renato D. Lopes and Amit N. Vora Oral Prostacyclin Pathway Agents in Pulmonary Arterial Hypertension: 47 An Expert Clinical Consensus Vallerie McLaughlin and Sean Gaine 2 EMJ • June 2020 • Cover Image © Anna Grigorjeva / 123rf.com EMJ “It is more important than ever that information is disseminated rapidly and responsibly in the face of such global threats” Spencer Gore, CEO + ARTICLES Editor's Pick: Bone-Related Markers of Cardiovascular Disease 54 Ernesto Maddaloni et al. National Institute for Health and Care Excellence (NICE) Guidelines on 63 Cannabis-Based Medicinal Products: Clinical Practice Implications for Epilepsy Management Rhys H. Thomas and Jacob Brolly The Role of Next-Generation Sequencing and Reduced Time to 76 Diagnosis In Haematological Diseases: Status Quo and Prospective Overview of Promising Molecular Testing Approaches Christina Ranft Bernasconi et al. Sebaceous Carcinoma: A Rare Extraocular Presentation of the Cheek 85 Ritu Swali et al. -
Clinical Pharmacology in the UK, C. 1950–2000: Industry and Regulation
CLINICAL PHARMACOLOGY IN THE UK, c. 1950–2000: INDUSTRY AND REGULATION The transcript of a Witness Seminar held by the Wellcome Trust Centre for the History of Medicine at UCL, London, on 25 September 2007 Edited by L A Reynolds and E M Tansey Volume 34 2008 ©The Trustee of the Wellcome Trust, London, 2008 First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2008 The Wellcome Trust Centre for the History of Medicine at UCL is funded by the Wellcome Trust, which is a registered charity, no. 210183. ISBN 978 085484 118 9 All volumes are freely available online at: www.history.qmul.ac.uk/research/modbiomed/wellcome_witnesses/ Please cite as: Reynolds L A, Tansey E M. (eds) (2008) Clinical Pharmacology in the UK c.1950-2000: Industry and regulation. Wellcome Witnesses to Twentieth Century Medicine, vol. 34. London: Wellcome Trust Centre for the History of Medicine at UCL. CONTENTS Illustrations and credits v Abbreviations vii Witness Seminars: Meetings and publications; Acknowledgements E M Tansey and L A Reynolds ix Introduction Professor Parveen Kumar xxiii Transcript Edited by L A Reynolds and E M Tansey 1 References 73 Biographical notes 89 Glossary 103 Index 109 ILLUSTRATIONS AND CREDITS Figure 1 AstraZeneca Clinical Trials Unit, South Manchester. Reproduced by permission of AstraZeneca. 6 Figure 2 A summary of the organization of clinical trials. Adapted from www.clinicaltrials.gov/ct2/info/glossary (visited 1 May 2008). 10 Figure 3 Clinical trial certificates (CTC) and clinical trial exemption (CTX), 1972–1985. Adapted from Speirs (1983) and Speirs (1984). -
Wellcome Four Year Phd Programme in Integrative Cell Mechanisms
2021 Wellcome Four Year PhD Programme in Integrative Cell Mechanisms Training the next generation of Molecular Cell Biologists Background and Aims of Programme The Wellcome Four Year PhD Programme in Integrative Cell Mechanisms (iCM) is closely associated with the Wellcome Centre for Cell Biology and trains the next generation of cell and molecular biologists in the application of quantitative methods to understand the inner workings of distinct cell types in different settings. A detailed understanding of normal cellular function is required to investigate the molecular cause of disease and design future treatments. However, data generated by biological research requires increasingly complex analysis with technological advances in sequencing, mass spectrometry/proteomics, super-resolution microscopy, Wellcome Centre for Cell Biology 2021 synthetic and structural biology generating increasingly large, complex datasets. In addition, innovations in computer sciences and informatics are transforming data acquisition and analysis and breakthroughs in physics, chemistry and engineering allow the development of devices, molecules and instruments that drive the biological data revolution. Exploiting technological advances to transform our understanding of cellular mechanisms will require scientists who have been trained across the distinct disciplines of natural sciences, engineering, informatics and mathematics. To address this training need, iCM PhD projects are cross-disciplinary involving two primary supervisors with complementary expertise. Supervisor partnerships pair quantitative scientists with cell biologists ensuring that students develop pioneering cross-disciplinary collaborative projects to uncover cellular mechanisms relevant to health and disease. We aim to recruit students with a variety of backgrounds across the biological and physical sciences, including Biochemistry, Biomedical Science, Cell Biology, Chemistry, Computational Data Sciences, Engineering, Genetics, Mathematics, Molecular Biology and Physics. -
Annual Report 2013
Annual Report 2013 “ Being active and having a positive outlook on life is what keeps me going every day.” Overview of 2013 “ Our performance in 2013 was defined by remarkable &R D output and further delivery of sustained financial performance for our shareholders.” Please go to page 4 for more More at gsk.com Performance highlights £26.5bn £8.0bn £7.0bn £5.2bn Group turnover Core* operating profit Total operating profit Returned to shareholders 6 112.2p 112.5p 13% Major medicines approved Core* earnings per share Total earnings per share Estimated return on R&D investment 10 6 1st 1st Potential phase III study starts in 2014/15 Potential medicines with phase III data in Access to Medicines Index Pharmaceutical company to sign AllTrials expected 2014/15 campaign for research transparency Front cover story Betty, aged 65, (pictured) has Chronic “ Health is important to me, Obstructive Pulmonary Disease (COPD). She only has 25% lung capacity. This means I try to take care of my she finds even everyday tasks difficult, but medicines and inhaled oxygen allow her to health with all the tools live as normal a life as she can. Betty’s mindset I have and do the best is to stay busy and active, so every week she goes to rehab exercise classes. that I can with it.” COPD is a disease of the lungs that leads to Betty, COPD patient, damaged airways, causing them to become North Carolina, USA narrower and making it harder for air to get in and out. 210 million people around the world are estimated to have COPD. -
Uzomis: at All Doses Compared to Those on Placebo
persistent and recurrent headache. The frequency and time to use of these additional WARNINGS treatments were also recorded. ZOMIG* (zolmitriptan) should only be used where a clear diagnosis of migraine Table 1 shows efficacy results for ZOMIG" in 5 placebo-controlled trials, 4 of which were has been established. multicenter. The percentage of patients with pain relief (grade 1/0) at 2 hours after treatment Risk of Myocardial Ischemia ami/or Infarction and Other Adverse Cardiac Events: (the primary endpoint measure) was significantly greater among patients receiving ZOMIG* 2DWB* has beMassccMedwMtmis^ chest siMfrJMkpste and 8ghtoe& UZomis: at all doses compared to those on placebo. In Study 3, which directly compared the 1 mg, which may resemble angina pectoris. Following the use of other 5-HTj 2.5 mg and 5 mg doses, there was a statistically significant greater proportion of patients with agonists, In rare cases these symptoms have been Identified as being the likely zolmitriptan tablets 2.5 mg headache response at 2 and 4 hours in the higher dose groups (2.5 mg or 5 mg) than in the result of coronary vasospasm or myocardial Ischemia. Rare cases of serious 1 mg group. There was no statistically significant difference between the 2.5 mg and 5 mg PHARMACOLOGICAL CLASSIFICATION coronary events or arrhythmia have occurred following use ot S-HTt agonists, dose groups for the primary endpoint measure of pain relief (1/0) at 2 hours, or at any other including ZOMIG*. ZOMIG* should not be given to patients who have documented 5-HTi Receptor Agonist time point measured. -
Drugs That Changed the World
Drugs That Changed the World Drugs That Changed the World How Therapeutic Agents Shaped Our Lives Irwin W. Sherman CRC Press Taylor & Francis Group 6000 Broken Sound Parkway NW, Suite 300 Boca Raton, FL 33487-2742 © 2017 by Taylor & Francis Group, LLC CRC Press is an imprint of Taylor & Francis Group, an Informa business No claim to original U.S. Government works Printed on acid-free paper Version Date: 20160922 International Standard Book Number-13: 978-1-4987-9649-1 (Hardback) This book contains information obtained from authentic and highly regarded sources. While all reasonable efforts have been made to publish reliable data and information, neither the author[s] nor the publisher can accept any legal respon- sibility or liability for any errors or omissions that may be made. The publishers wish to make clear that any views or opinions expressed in this book by individual editors, authors or contributors are personal to them and do not neces- sarily reflect the views/opinions of the publishers. The information or guidance contained in this book is intended for use by medical, scientific or health-care professionals and is provided strictly as a supplement to the medical or other professional’s own judgement, their knowledge of the patient’s medical history, relevant manufacturer’s instructions and the appropriate best practice guidelines. Because of the rapid advances in medical science, any information or advice on dosages, procedures or diagnoses should be independently verified. The reader is strongly urged to consult the relevant national drug formulary and the drug companies’ and device or material manufacturers’ printed instructions, and their websites, before administering or utilizing any of the drugs, devices or materials mentioned in this book. -
API Written Confirmation 02-08-2021
MHRA Register of Written Confirmations For UK Active Substance Manufacturers The information published in this document was that held by the MHRA on the date of publication. Please note the site register will be updated on a Monthly basis. Date of Publication: 02/08/2021 Copyright © by the Department of Health and Social Care and MHRA, 10 South Colonnade, Canary Wharf, London E14 4PU T 020 3080 6000 – www.mhra.gov.uk NOTICES The Agency’s register is computerised. Every site and every Written Confirmation has a unique number that should be quoted when enquiries are made. NOTES FOR GUIDANCE GENERAL The Written Confirmations have been generated for UK Active Substance Manufacturing sites to support the export of Active Substances to the EEA. The Written Confirmation Number is a specific number allocated to each site. The Table of Contents contains a link to the relevant Written Confirmation for each company within this document. Table of Contents A NELSON AND COMPANY LIMITED AIR PRODUCTS PLC ALBUMEDIX LIMITED ALLIANCE MEDICAL RADIOPHARMACY LIMITED ALLIANCE MEDICAL RADIOPHARMACY LIMITED ALMAC SCIENCES (SCOTLAND) LIMITED ALMAC SCIENCES LIMITED APTUIT (OXFORD) LIMITED APTUIT (OXFORD) LIMITED ARC TRINOVA LIMITED BASILDON CHEMICAL COMPANY LIMITED BAXTER HEALTHCARE LIMITED BAXTER HEALTHCARE LIMITED BIO PRODUCTS LABORATORY LIMITED BSPG LABORATORIES LIMITED CATALENT MICRON TECHNOLOGIES LIMITED COURTIN & WARNER LIMITED CRODA EUROPE LIMITED CRODA EUROPE LIMITED DR REDDY'S LABORATORIES (EU) LIMITED DSM NUTRITIONAL PRODUCTS (UK) LIMITED EUROAPI UK LIMITED -
Blunted Endogenous Opioid Release Following an Oral Dexamphetamine Challenge in Abstinent Alcohol- Dependent Individuals
View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by Explore Bristol Research Turton, S., Myers, J. F. M., Mick, I., Colasanti, A., Venkataraman, A., Durant, C., ... Lingford-Hughes, A. (2018). Blunted endogenous opioid release following an oral dexamphetamine challenge in abstinent alcohol- dependent individuals. Molecular Psychiatry. https://doi.org/10.1038/s41380-018-0107-4 Publisher's PDF, also known as Version of record License (if available): CC BY Link to published version (if available): 10.1038/s41380-018-0107-4 Link to publication record in Explore Bristol Research PDF-document This is the final published version of the article (version of record). It first appeared online via Nature Publishing Group at https://www.nature.com/articles/s41380-018-0107-4 . Please refer to any applicable terms of use of the publisher. University of Bristol - Explore Bristol Research General rights This document is made available in accordance with publisher policies. Please cite only the published version using the reference above. Full terms of use are available: http://www.bristol.ac.uk/pure/about/ebr-terms Molecular Psychiatry https://doi.org/10.1038/s41380-018-0107-4 ARTICLE Blunted endogenous opioid release following an oral dexamphetamine challenge in abstinent alcohol-dependent individuals 1 1 1,2 3,4 1 1 Samuel Turton ● James FM Myers ● Inge Mick ● Alessandro Colasanti ● Ashwin Venkataraman ● Claire Durant ● 5 6 6 7 8,9 8,10 Adam Waldman ● Alan Brailsford ● Mark C Parkin ● Gemma Dawe ● Eugenii A Rabiner ● Roger N Gunn ● 11 1 1 Stafford L Lightman ● David J Nutt ● Anne Lingford-Hughes Received: 21 September 2017 / Revised: 9 May 2018 / Accepted: 14 May 2018 © The Author(s) 2018. -
260 Book Reviews
Book Reviews relation to the development of neurology as a arguments of Kant or Goethe, or indeed medical specialty and to knowledge of the Alexander Bain, were not? brain. (This in part perhaps reflects the lack of This “life” will give great pleasure and archival material on Head’s scientific work.) interest to many readers, perhaps most of all In particular, Head’s career as a theorist draws to those who, like Head himself, find both on the work of John Hughlings Jackson, work the sciences and the arts personally which, so Head claimed, had been almost indispensable. totally ignored. Had it? What reception did Head’s theory of sensation have? The Roger Smith, biography does not enable us to judge Head’s Moscow originality. (For Jackson, one should turn, perhaps the message is, to Jacyna’s earlier fine study, Lost words: narratives of language and Roy Church and E M Tansey, Burroughs the brain, 2000.) Head’s functionalist way of Wellcome & Co.: knowledge, trust, profit thinking encouraged him to mix physiological and the transformation of the British and psychological languages and therapies. pharmaceutical industry, 1880–1940, How special was this? Secondly, the book Lancaster, Crucible Books, 2007, pp. xxvii, does look “outwards” from the archive, as 564, illus. £19.99, $39.99 (paperback 97801- opposed to using the archive to illuminate the 905472-07-9). man, in two regards. The first of these, naturally, is to use the individual career to This work, based on detailed research of the illustrate contemporary medical practice. In firm’s archives, aims to tell the history of addition, however, Jacyna proposes a large Burroughs Wellcome, founded by Silas thesis, which gives the book its title, that Burroughs and Henry Wellcome in 1880, Head’s manner of life and work makes him an which eventually became the largest British exemplary “modernist”. -
British Thoracic Society Winter Meeting
February 2021 Volume 76 Supplement 1 76 S1 Volume 76 Supplement 1 Pages A1–A256 ThoraxAN INTERNATIONAL JOURNAL OF RESPIRATORY MEDICINE British Thoracic Society THORAX Winter Meeting Wednesday 17 to Friday 19 February 2021 Programme and Abstracts February 2021 February thorax.bmj.com PROGRAMME AND Thorax ABSTRACTS British Thoracic Society Winter Meeting Wednesday 17 to Friday 19 February 2021 Programme and Abstracts Approved by the Federation of the Royal Colleges of Physicians of the UK for 18 category I (external) credits (6 credits per day). Code: 133787 DAILY PROGRAMME WEDNESDAY 17 FEBRUARY 2021 All Symposia, Guest Lectures, Journal Clubs and Spoken Sessions will be shown online live at the times below, and will be available to view via the relevant ‘session type’ tab online. Poster presentations will be pre-recorded and available on demand each day and should be viewed prior to the Poster Discussion Q&A, which will be online live at the times below, all via the ‘Poster Sessions’ tab. Time Session Type Session Title 7.00am – 6.00pm Poster viewing on demand P1-P11 Lessons from COVID-19 throughout the day with live P12-P24 Lung cancer: treatment options and care pathways discussions at the programmed P38-P51 COPD: clinical science times P63-P75 Primary care and paediatric asthma P76-P88 Virtually systematic: current interventions and digital delivery in pulmonary rehabilitation 7.45am – 8.00am Symposium Daily preview 8.00am – 8.30am BTS Journal Club New insights to chronic cough 8.30am – 10.00am Symposium Neutrophilic asthma 8.30am – -
94771408.Pdf
VSB — TECHNICAL UNIVERSITY OF OSTRAVA FACULTY OF ECONOMICS DEPARTMENT OF FINANCE Zhodnocení finanční pozice společnosti GlaxoSmithKline, a.s. Evaluation of Financial Position of the Company GlaxoSmithKline plc. Student: Xinran Chen Supervisor of the bachelor thesis: Ing. Ingrid Petrová, Ph.D. Ostrava 2017 Content 1 Introduction ......................................................................................................................... 4 2 Description of the Financial Analysis Methodology ........................................................... 6 2.1 Goal of financial analysis ......................................................................................... 6 2.2 Source of data for financial analysis ......................................................................... 7 2.2.1 Balance sheet .................................................................................................. 7 2.2.2 Income statement ............................................................................................ 9 2.2.3 Cash flow statement ..................................................................................... 10 2.3 Common-size analysis ............................................................................................ 12 2.3.1 Vertical common-size analysis ..................................................................... 12 2.3.2 Horizontal common-size analysis ................................................................ 13 2.4 Financial ratio analysis ..........................................................................................