Anti-TNIP1-Antibody Pack Size

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TECHNICAL DATA SHEET Cat No: Kab08831 Product Particulars: anti-TNIP1-antibody Pack Size: 100μg Pack Size: Pack Size: 100μg Purify: Immunogen affinity purified Host: Rabbit Isotype: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Ԩ for 24 months (Avoid repeated freeze / thaw cycles.) Background (Function): Inhibits NF-kappa-B activation and TNF-induced NF-kappa- B-dependent gene expression by regulating A20/TNFAIP3-mediated deubiquitination of IKBKG; proposed to link A20/TNFAIP3 to ubiquitinated IKBKG. Involved in regulation of EGF-induced ERK1/ERK2 signaling pathway; blocks MAPK3/MAPK1 nuclear translocation and MAPK1-dependent transcription. Increases cell surface CD4(T4) antigen expression. Involved in the anti- inflammatory response of macrophages and positively regulates TLR- induced activation of CEBPB. Involved in the prevention of autoimmunity; this function implicates binding to polyubiquitin. Involved in leukocyte integrin activation during inflammation; this function is mediated by association with SELPLG and dependent on phosphorylation by SRC-family kinases. Interacts with HIV-1 matrix protein and is packaged into virions and overexpression can inhibit viral replication. May regulate matrix nuclear localization, both nuclear import of PIC (Preintegration complex) and export of GAG polyprotein and viral genomic RNA during virion production. In case of infection, promotes association of IKBKG with Shigella flexneri E3 ubiquitin-protein ligase ipah9.8 p which in turn promotes polyubiquitination of IKBKG leading to its proteasome-dependent degradation and thus is perturbing NF-kappa-B activation during bacterial infection. Immunogen: TNFAIP3 interacting protein 1 Synonyms: KIAA0113, NAF1 Calculated MW: Uniprot ID: Q15025 Specificity: Human Tested Application: ELISA,WB,IHC,IF,IP Recommended Dilution: Gene ID: 10318 Gene Location: Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE" OUR KINESISDX COMMITMENT : GUARANTEED QUALITY WITH EXPERT TECHNICAL SUPPORT .

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Acute Lymphoblastic Leukemia Patient with Variant ATF7IP
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