Burden of Disease Air pollution among top killers

Air pollution and Our Health: Setting the agenda

Centre for Science and Environment New , February 13, 2013

Why it has become necessary to talk about air pollution and our health again….

Winter of 2012-13: Severe and consistent pollution episodes

PM10 and PM2.5 Three major pollution episodes 1) 29 October to 7 November, 2012: PM2.5 5 to 9 times higher than the standard. PM10 5 to 7 times the standard. NO2 close to twice the standard

NO2 2) 22 – 27 December 2012: Both PM10 and PM2.5 four times the standard. NO2 close to double the standard.

3) 11 January February 2013: PM levels 3 times higher than the standard. Number of days with critical pollution level skew during winter months

PM10 classification of daily levels PM2.5 classification of daily levels

NO2 classification of daily levels Aial aids…….Soke fo Punjab hogged news this year

October 2012: This is NASA image of smoke plume from agricultural burning in neighbouring states Are there clean cities in ?

Out of 180 cities monitored for SO2, NO2 and PM10 in 2010, only two towns Malapuram and Pathanamthitta in Kerala met the criteria of low pollution (50% below the standard) for all pollutants. More cities in grip of pollution

-- PM10 monitoring increased from 96 cities in 2005 to 180 cities in 2010. NO2 monitoring increased from 100

-- Low polluted cities fallen from 10 to 2. -- cities to 177 cities Critically polluted cities (1.5 times the standards) 2005: Only 1 city exceeded the increased from 49 to 89 cities. standard. 2010: 19 cities

-- 2005: 75% of cities exceeded the standard. 2010: -- 78% of cities Spot your city…….

PM10 PROFILE OF CITIES NO2 PROFILE OF CITIES Critical , West Singhbhum, , , Delhi, Howrah, Barrackpore, Badlapur, Ulhasnagar, , Durgapur, Sankrail, Yamunanagar, Usgao, Jharia, Khanna, Alwar, Raniganj, Gobindgarh, , , Bhatinda, , Ferozabad, Rishikesh, , , Haldwani, Muradabad, Satna, , , , , Byrnihat, Sindri, Khurja, , Saraikela Kharsawan, , , , Dera Bassi, Dehradun, Raniganj, , Chandrapur, Jalandhar, Patiala, Asansol, Durgapur, Haridwar, Paonta Sahib, , , Kota, Noida, Anpara, , Jalgaon, Barrackpore, , Lote, Tuticorin, Amravati, Jhansi, Howrah, Talcher, Udaipur, Jammu, Navi , , Badlapur, Angul, , Ulhasnagar, Latur, Baddi, Rourkela, Korba, Jamnagar, Nagaon, Ponda, Sankrail, Kolkata, Mumbai, , , Hissar, Nagda, Guwahati, Naya Nangal, Vijaywada, , Mahad, , Hubli Dharwad, Codli, Bicholim, , Roha, Gajraula

High Nalagarh, Nalgonda, Kurnool, Panaji, Dewas, Salem, Parwanoo, South Suburban, Delhi, Haldia, Bicholim, Jamshedpur, Meerut, Noida, Saraikela Kharsawan, Bhubaneshwar, Kolhapur, , South Suburban, , Silchar, Jalgaon, Raipur Vapi, Ujjain, , Kala Amb, Shillong, , Ankleshwar, Patencheru, Lakhimpur, , , Dimapur, Pathankot/Dera Baba, , Cuttack, Golaghat, Balasore, Vishakhapatnam, Assanora, Dawki, Ramagundam, Nalbari, Tezpur, Damtal, Solapur, Sagar, Kohima, Nellore, Gulbarga, Tura, Kothagudem, Sangli, Vasco, ,

Moderate Sibsagar, Marmagao, Singrauli, , Tinsukia, Bongaigaon, Patna, Navi Mumbai, Pune, Jharia, Mahad, Ghaziabad, Sindri, Jaipur, Amritsar, Dhanbad, Gobindgarh, Daranga, Shimla, Rayagada, Berhampur, Haldia, Trivandrum, Amona, Ranchi, Solapur, Lucknow, Kanpur, Udaipur, Roha, Ferozabad, Nagpur, West Singhbhum, Ludhiana, , Thane, Sambalpur, , Kottayam, , , Khanna, Bangalore, Dehradun, Lote, Faridabad, Jalandhar, Kota, Vadodara, Anpara, , Khurja, Wayanad, Kashipur, Hassan, Mysore, Alappuzha, , Aizwal, Jamnagar, Codli, Coimbatore, Sangli, Yamunanagar, Chandrapur, Salem, Nashik, Jabalpur, Jhansi, Chitoor, Silvassa, Dibrugarh, Curchorem, Puducherry, Tirupati, Daman, Ponda, Madurai, Alwar, Allahabad, Nagda, Vapi, Hyderabad, Ankleshwar, Surat, Trivandrum, Dera Belgaum, Palakkad, Thissur, Bassi, Talcher, Nalgonda, Patencheru, Jodhpur, Bhilai, Gajraula, Kolhapur, Hassan, Bhatinda, Muradabad, Angul, Korba, Ahmedabad, Aurangabad, Cuttack, Gwalior, Agra, Patiala, Varanasi, Rayagada

Low Malapuram, Pathanamthitta in Kerala Mumbai, Vasco, Singrauli, Kottayam, Bilaspur, Bhopal, Indore, Nalagarh, Dewas, Bhubaneshwar, Kala Amb, Marmagao, Amona, Silvassa, Daman, Paonta Sahib, Rajkot, Panaji, Sagar, Kochi, Curchorem, Latur, Baddi, Naya Nangal, Chandigarh, Silchar, Vishakhapatnam, Assanora, Nalbari, Tinsukia, Byrnihat, Jammu, Guwahati, Lakhimpur, Golaghat, Chennai, Bongaigaon, Sambalpur, Kollam, Belgaum, Amravati, Nagaon, Vijaywada, Pathankot/Dera Baba, Sibsagar, Daranga, Thane, Dibrugarh, Hubli Dharwad, Ujjain, Tezpur, Gulbarga, Shimla, Berhampur, Puducherry, Pathanamthitta, Tuticorin, Parwanoo, Balasore, Ramagundam, Nellore, Wayanad, Rourkela, Guntur, Damtal, Kothagudem, Usgao, Shillong, Warangal, Kurnool, Tura, Kozhikode, Chitoor, Tirupati, Hissar, Mangalore, Dimapur, Thissur, Satna, Dawki, Aizwal, Palakkad, Kohima, Alappuzha, Malapuram

Source: Based on CPCB air quality data It is about people……

•Close to half of total urban population breath the air which 50% of cities monitored are exceeds the standard of PM10. critically polluted for PM10

One third of urban population live in …… But 60% of people i • monitored cities live in areas with cities with PM10 levels classified as critical PM10 levels critical -- close to Japan’s population.

10% of total urban population breathes the air which exceeds the standard of NO2.

Source: CSE based on CPCB air quality data and Census population data Changing positions of hotspots

Non-metro cities have higher levels of PM10

Cities with high PM10 annual Cities with high levels PM10 annual levels average in average in 2005 2010

Ghaziabad 339 Gwalior 308 Gobindgarh 241 West Singhbhum 302

Ludhiana 233 Ghaziabad 290 Raipur 203 Raipur 289 Lucknow 192 Delhi 261 Satna 190 Yamunanagar 261 Kanpur 189 Usgao 245 Jalandhar 187 Jharia 237 Agra 183 Khanna 231 Jamshedpur 166 Alwar 225

Source: Computed from the data provided by the CPCB Mixed trends in cities

--PM10: Stablised in Ahmedabad, Kolkata, Hyderabad, Chennai —Increased -- Delhi. Bangalore and Mumbai show a decline in recent years --NO2: Stabilised in -- Ahmedabad, Chennai, Hyderabad, Increasing in Delhi, and Kolkata PM10

NO2 South Asia: Very high PM10 levels

Source: Based on WHO air quality database

Delhi has lost its gains. After a short respite pollution curve turns upward

240 70 RSPM Nitrogen

60 dioxide

180 50

40 120 30

20

60 NO2microgram/cu.metrein RSPMmicrogram/cu.metrein 10

0 0 2000 2001 2002 2003 2004 2005 2006 2007 2008 2000 2001 2002 2003 2004 2005 2006 2007 2008

Based on CPCB data Ozone exceedanceThe has begun new in Jan-Febdanger: ozone

Source: Based on DPCC air quality data Percentage of days exceeding hourly Ozone standards (Siri Fort, 2008-2010)

100 90

80 2008 2009 2010 70 65 61 60 50 45 40 32 29 30 23 23 20 20 20 13 11 13 12 10 8 9 10 10 6 % of days exceeding the 8-hr standard standard 8-hr exceedingthe days of % 0 0 0 0 0 0 0 0 0 0 0 Jul-08 Jul-09 Jun-08 Oct-08 Jun-09 Oct-09 Apr-08 Apr-09 Jan-08 Apr-10 Jan-09 Jan-10 Mar-08 Mar-09 Mar-10 Nov-08 Nov-09 Feb-08 Feb-09 Feb-10 Aug-08 Aug-09 May-08 Sep-08 May-09 Sep-09 Dec-08 Dec-09 Proximity to source matters…..

Stunning evidences in Delhi --- Commuters breathe far more harmful particles inside vehicles while traveling compared to the ambient concentration. -- The PM2.5 concentrations inside vehicles can be 1.5 times higher than the surrounding background air and ultra-fine levels about 8.5 times higher. -- The short-term peaks during travel can go above 1000 microgramme per cum – nearly 16 times the daily limit. (University of California, Berkeley research in Delhi)

Influence of traffic maximum upto 500 meters from roadside. Health Effects Institute estimates that about 55% of Delhi’s population live in that influence zone. (Health Effects Institute on Delhi)

Moutig gloal health evidees…..

Numerous studies of varying scale and scope

Scale of studies ---- Eg. the Arden Pope study (Journal of American Medical Association 2002) based on American Cancer Society data …..16 years, about 500,000 people in 116 metropolitan areas to arrive at irrefutable findings.

……… a mere increase of 10 microgramme per cum of PM2.5 can increase the risk of lung cancer by 8 per cent, cardiopulmonary deaths by 6 per cent, all deaths by 4 percent.

These findings are equally valid for India …. Human health is same…….

India has its own health evidences too….. Mounting evidences……

More than 72% studies after 1998 Surprise! Most studies done by doctors themselves…….

Who has done the studies?

Source: CSE Emerging evidences in Indian cities

Studies in large number of cities

Now studies on smaller cities as well Interesting …. About 60% studies have focused on exposure to traffic pollution…specially those occupationally exposed…………

Source: CSE Studies have responded to the eegig oes i ai uality…

-- Early years: Primary focus on SPM, SO2, and little on NOX – nearly 60%

-- Subsequent years: A wider pollutant basket: VOCs, PM2.5, PAH VOCs etc PAHs -- Benzene and its Ozone impacts in more than Benzene 10% of studies since CO 2000. -- VOCs and PAHs in a PM2.5 few studies since PM10 2000. Nox -- But very little on SPM ozone – only one in SO2 Delhi….. 1985 1990 1995 2000 2005 2010 Source: CSE Studies looking at a more diverse health end points….

Preditaly respiratory health syptos doiate…. Broadens to other health end points – cardiovascular, eye disorders, cellular changes, aer, preature deaths….

43 No. of studies of No.

8 6 7 6 4 3 Effects studied

Respiratory Cardio Cancer Related Eye related Cytogenetic Mortality Others

Source: CSE Global studies …. Looking beyond lungs ……

Diabetes: First large-scale population-based study links diabetes with air pollution. Increase in insulin resistance in lab test …. and an increase in markers of inflammation (which may contribute to insulin resistance) after particulate exposure. Strong and consistent association between diabetes prevalence and PM2.5 concentrations. For every 10 μg/m3 increase in PM2.5 exposure, there was a 1 percent increase in diabetes prevalence. Counties with highest versus the lowest levels of PM2.5 pollution had a more than 20% increase in diabetes, which remained after controlling for diabetes risk factors. (Diabetes Care 2011)

Heart: Acute Effects of Fine Particulate Air Pollution on Cardiac Arrhythmia:Conclusion: PM2.5 exposure within approximately 60 min was associated with increased PVC counts in healthy individuals. (He F et al 2011The APACR Study. Environ Health Perspect)

Blood pressure Traffic-related Air Pollution and Blood Pressure in Elderly Subjects With Coronary Artery Disease: Found positive associations of systolic and diastolic BP with air pollutants. The strongest associations were with organic carbon, multiday average exposures, ect. (Delfino, Ralph J.a et al 2010,, Epidemiology, May 2010)

Effect on foetus: Studies have shown damaging impact of PAH on even fetus

Source: CSE India’s unique public health challenge

• The Asiawide review of existing studies show that the estimated health effects are similar to those found in the extensive studies in western countries.

• But the risk in south Asia could be more serious. Science has yet to assess our unique risk factors

• Extremely high levels of particulates and pollution cocktail -- the problem of exposure to multiple pollutants • • Impact of poverty: Socio economic variables are not included in health studies to influence public policy. Sporadic studies elsewhere show poor are more susceptible

Understand risk transition

• Double burden of disease. Modern or community risks increasing

• This has important implication for environmental monitoring strategies

Source: CSE

The vulnerable………children, poor, elderly, city dwellers……. Children…..

Children more susceptible -- low breathing zone; time spent outdoors; immature immunity; developing organs…………..

Effects of air pollution on the respiratory health of children: Respiratory symptoms in 32% of children in Delhi, in contrast to only 18.2% of the rural Photomicrographs showing children. (Delhi (2010) IIT Guwahati; CNCI Kolkatal particle-laden alveolar NEWS Kolkata & Health Canada) macrophages in sputum

saples of a Delhi’s shool Air pollution lung function of children in Delhi, children. Lung function reduced in 43.5% school children in Delhi as compared to 25.7% of control group.PM10 blamed for lung function deficits.(Delhi (2010) : IIT Guwahati; CNCI Kolkatal NEWS Kolkata & Health Canada)

Attention-deficit hyperactivity disorder (ADHD) in children chronically exposed to high level of vehicular pollution (2010): (IIT Guwahati; CNCI Kolkata; NEWS Kolkata; & Health Canada)

The impact of atmospheric pollution on vitamin D status of infants and toddlers: Delhi (2002): St. StephensSource: CSE Hospital, Delhi: Toxic risk

The endpoint of the toxic risk is cancer

-- In India over 700,000 new cases and 300,000 people are set to die every year, estimates the National Cancer Control Programme (NCCP).

-- NCCP’s forecast -- by 2026, more than 1.4 million people will be falling in the grip of the disease.

-- NCCP has listed greater exposure to environmental carcinogens as one of the most important reasons.

-- Mitigation strategy must reduce environmental risk from all factors – and air pollution is an important factor

Then came the shockers ………………. Global Burden of disease………

December 2012

Globally air pollution related deaths have increased by 300 per cent since 2000. About 65 per cent of these deaths occur in Asia.

Air pollution ranked among the top 10 killers in the world

Two-thirds of the death burden from outdoor air pollution occurs in developing Asia

How about India? Don’t know yet……. Cancer risk of diesel

June 2012

The WHO/ International Agency on Cancer Research reclassify diesel emissions as class 1 carcinogen, -- same class as tobacco for its strong link with lung cancer.

But India is dieselising very rapidly

Source: MP Walsh CSE asked the Delhiites: -- Has city’s air quality worsened? -- What are the dominant sources of air pollution in the city and in their vicinity? -- Frequency and type of respiratory ailments in their family Majority have complained of -- Are they aware of the pollution multiple symptoms this winter episodes? -- Are they aware of the release of the Global Burden of disease report? -- Do they know that the WHO-IARC has reclassified diesel emissions as class 1 carcinogen? -- The key mitigation strategies they support What have Delhites said?

-- 64% have said air pollution is worsening. 26% -- it has remained the same.

-- 79% blame growing number of vehicles.

-- 77% say vehicles are closest source of pollution around their residences, offices

-- 74% say air pollution cause respiratory problems and respiratory symptoms. Report increased in frequency this winter. About 14% have said this has increased school absenteeism amongst children

-- Close to half say that doctors mention air pollution as one of the causal factors

-- Close to one third of the respondents have said that they are aware of the new Global Burden of disease estimates

-- 26% of Delhiites know that the WHO and International Agency on Cancer Research have reclassified diesel emissions as class 1 carcinogen, -- same class as tobacco for its strong link with lung cancer.

Delhiites response to mitigation…..

Response to individual mitigation strategies

-- Strong support for public transport walking and cycling. (64% and 70%)

-- 47% support reduction in car numbers.

-- 62% want restraint on diesel cars and SUVs on dirty diesel. -- Support for clean fuel in power plants

-- 66% say reduce dependence on gen sets.

Policy murmur…………..

We have enough evidences to act and influence…

12th five year plan: Urban areas to meet the air quality standards by 2017.

The 12th plan highlights need for epidemiological studies

Planning Commission working on environment performance index to incentives states for environmental performance through budgetary allocation.

National Health Research Policy: will this address health concerns related to air pollution?

Clean Air Action Plan in cities….

Way forward…………..

India cannot afford to ignore health evidences anymore

Make National Ambient Air Quality Standards legally binding: The national air quality planning and city action plans need a roadmap for each source of pollution and aggressive measures. Impose penalty on cities if air quality standards are violated. Account for health cost in decision making: Valuation of acute and chronic illnesses must be linked to decision on air pollution control measures. Need stringent vehicle technology and fuel quality roadmap. Need urgent timeline for Euro V and Euro VI emissions standards. Restrain dieselization. Strengthen implementation plans for critically polluted areas

Need public information system on daily air quality with health advisories and implement smog alert and pollution emergencies measures Control and cut explosive increase in vehicle numbers by scaling up public transport, non-motorised transport, compact city planning and car restraint measures Let us manage the health risk transition well….

The cost of inaction is very high

We cannot afford to wait……………..

Let us begin the discussion….