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Grant Application for 2019-2021

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Grant Application for 2019-2021 ISP Uppsala Universitet Deadline Box 549 IPPS 15 August 2018 SE-751 21 Uppsala, Sweden Fax +46184713495 IPICS 2 September2018 [email protected] I Grant application for 201I 9-2021 Research Groups and Scientific Networks Submit this application and enclosures by email attachment with a scanned/photographed copy of the first signed page. Read the separate document Guidelines for Enclosures and Budget for more information. Hover your pointer over theblueunderlinedwordsin this document for specific instructions.NOTE! ISP manages personal data (with care and only as long as necessary) provided on this form and in enclosures in order to honor the agreements with you and with Sida. Program Activity code(if settled) Chemistry X Other ☐ ANRAP Mathematics ☐ Physics ☐ Applicant(Research group leader/Network coordinator: title, given name, family name) EMERITUS PROFESSOR MOHAMMED MOSIHUZZAMAN Deputy: Address Department/unit: ANRAP Secretariat University/institute: Bangladesh University of Health Sciences(BUHS), Room No:C-14 Street (visiting address): Darussalam, Mirpur P.O Box number: Post/zip code: Dhaka-1216 City:Dhaka Country: Bangladesh E-mail address(es):[email protected];[email protected] Website: www.anrap.org Telephone and telefax Office Mobile Fax 88-02-8035501-06 8801755654160 (Ext 1312) Name of Research Group/NetworK ASIAN NETWORK OF RESEARCH ON ANTIDIABETIC PLANTS (ANRAP) City: Approved by the Department: ………………………………………………………/ Date: Signature by Head of Department/Name in printing: Summary of budget request (SEK) 2019 2020 2021 Total Equipment/spare parts/service 18,000 29,000 58,000 105,000 Consumables/literature/field work 68,000 76,000 76,000 220,000 Conferences/workshops 231,000 170,000 229,000 630,000 Exchange visits by cooperating scientists 10,000 10,000 8,000 28,000 Fellowships for training: 70,000 70,000 75,000 215,000 Support to students 10,000 20,000 10,000 40,000 Costs for audit and RG meeting 10,000 10,000 30,000 50,000 NetworK (only) administration costs 53,000 65,000 64,000 182,000 Total 470,000 450,000 550,000 1,470,000 The following enclosures are submitted Yes / No City: DhaKa 1) Research plan/network program Yes Date: 01 August 2018 2) Applicant’s/Deputy’s CV Yes 3) Publications/Theses/Abstracts Yes 4) Application for improving gender balance 5) Fellowship application(s) Applicant’s signature 6) Other (Specify:…………………………………………..........) Yes 1 (26) Deadline 2018 – see isp.uu.se/documents 1. Summary of proposed research/network activity (Research plan/Network program) (Full details should be given in Enclosure 1Please, carefully read and follow guidelines) Give a summary (half a page) of the research plan/networK program by briefly describing the planned activity and its justification, and for scientific research clarify the justification in relation to previous research/literature,postulate the hypotheses to be tested/research questions to be addressed, and indicate which methods will be used.Please note that this is a summary of Enclosure 1, Sections a – c. ANRAP was launched in Dhaka in 1994 as an outcome of collaborative research between BIRDEM and Dhaka University (DU) on antidiabetic plants. Since ANRAP was initiated in Dhaka, research activities on antidiabetic plants in the laboratories of BIRDEM and DU and now atBUHS became the focal point laboratory of the network. ANRAP acted as a planning coordinator and supervising organization to integrate the activities of various laboratories in the Asian Region.Through the course of time a number of important laboratories are now working synchronically under the umbrella of ANRAP. In the coming three years ANRAP will continue with its present activities of training Research Fellows from home and abroad, conduct National, Regional and International (every 3 years) Seminers and hold the hands-on-training workshop every year. Considering the practical use of herbal medicine specially in the poorer third world countries ANRAP has expanded its activityto scientifically evaluate antidiabetic herbal medicine (HM).HM, used for the treatment of other noncommunicable diseases will also be studied. In addition, in the next three years ANRAP will particularly give emphasis on the development of interlaboratory cooperation (NetHerb) for testing of herbal medicines. With this end in view ANRAP organized an International workshop on networking of ”Afro-Asian laboratories working on herbal medicine” in Dhaka, Bangladesh on 29-30 October, 2016 followed by a second meeting with representatives from laboratories in the Afro-Asian region in Kandy, Sri Lanka in January 2018.After detailed discussionsfour laboratories agreed to collaborate. An MOU will be signed among the collaborating laboratories in the upcoming 9th ANRAP International seminar that will be held in Karachi, Pakistan on 25-27 January, 2019. So the next target is to start in-depth research on herbal medicine incorporating Chemistry, Biochemistry, Pharmacology and ultimately preclinical toxicological studies and human trial. 2. Give an overview of objectives, planned outputs and expected outcomes Provide a summary of objectives, planned outputs and expected outcomes (and, if found convenient, formalized in the Logical Framework Matrix).Provide your answers under the below headings. This is a summary of Enclosure 1, Section d. 2 (26) Deadline 2018 – see isp.uu.se/documents Overall objective (impact) and relevance of the activity: ANRAP is a network of natural product scientists and participating laboratories working on or are planning to work on antidiabetic plant materials.During the last three years, research capabilities of Bangladesh University of Health Sciences (BUHS) has been strengthened. Chemistry and Pharmacology laboratories of BUHSare capable of conducting research on antidiabetic HM as well as on HM for other noncommunicable diseases. ANRAP has the following overall objectives: • Compilation of information on antidiabetic plants and herbal medicines reported in scientific literature and including those from producers,traditional healers, formal practitioners and users. • Conduct research on the chemical constituents and biological activities to assess the safety, efficacy and standardization of antidiabetic plants and herbal medicines used by millions of people across the world, and bring them within acceptable limits. • Isolation, characterization and testing of biological activity of pure compounds or fractions. • Optimize, coordinate and utilize the facilities existing in various laboratories for the purpose of fruitful research on antidiabetic plant materials and herbal medicine used for the management of diabetes and other non-communicable diseases prevalent in the region. Specific objectives for the granting period: • Training of young scientists and Fellowsincluding PhD studentsin the field of antidiabetic plant and HM research. • Holding of ANRAP Regional Workshop on Chemical Studies and Bioassay of antidiabetic plant materials (Participants will be from Bangladesh, Nepal, India, Pakistan, Sri Lanka, Malayasia and Mauritius) • Developing a network of herbal medicine(NetHerb) with representatives from different participating laboratories. • Evaluation of safety and efficacy of some antidiabetic HM and HM used for other diseases like hepatitis, hypertension and renal disorders. • Conducting preclinical and toxicological studies and clinical trial of some antidiabetic and other HM. 3 (26) Deadline 2018 – see isp.uu.se/documents • Arrange exchange of visits of scientists working in the field by arranging National, Regional and International (every 3 years) seminars on antidiabetic plants &herbal medicines and those used for other diseases. Expected outcomes of the activity: Scientific Results: • Masters and PhD thesis will be produced. Papers will bepublished in national and international journals. Patents on new scientifically evaluated herbal medicine can be produced. • More collaborative research linkage will be established. • Safety and efficacy of antidiabetic and other herbal medicine for other diseases will be evaluated. • Development of new drugs from plant and commercial herbal medicine through collaboration in national and international level. • An arrangement has been done between GK Pharma (Unani) Ltd to carry out chemical & biological studies on hepatotoxic model animals with hepatoprotective herbal drug (Holy Liv) produced in Bangladesh. Graduations: A number of post graduate students will be trained up. They will be working to produce their thesis and publish papers. Trained young scientists including post graduate students will be produced to work in the field of plant & herbal medicine research. Dissemination(publications/conference contributions,etc): • Training of young scientists and post graduate students. • National, Regional and International Workshops/Seminars on Chemistryand Biology of plant materials and herbal medicine for the management & treatment of diabetes and other diseases. • Publications of scientific articles in peer reviewed journals. • Conference reports/ Published Proceedings of Conferences. ScientificExchange A good number of exchange visits within the region and organizations of different national, regional and international Seminars & Conferences will enhance collaborative research and exchange of knowledge and skill of the researchers working in this field. 4 (26) Deadline 2018 – see isp.uu.se/documents Interactions with government and society (outreach): ANRAP has very good interaction with the Ministry of Science & Technology, Bangladesh Government
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